An automated device for inducing hypertrophy of the ligamentum flavum in mice

Abstract

This utility model relates to the technical field of experimental devices for inducing mouse hypertrophy, specifically disclosing an automated device for inducing ligamentum flavum hypertrophy in mice. The device includes: a water tank and a water container mounted on one side of the water tank; a wastewater tank is located on one side of the water container and is fixedly installed on the adjacent outer wall of the water tank; multiple experimental tubes are arranged in a linear array inside the water tank; filter holes are penetrating the bottom and lower outer end of each experimental tube; a funnel-shaped cap is provided on the top of each experimental tube, and an iron mesh is fixedly installed on the inner wall of the cap; this utility model effectively reduces water waste and achieves automation through timed and quantitative water release and wastewater discharge, reducing the burden on operators and improving the practicality of the device.

Description

Technical Field

[0001] This invention belongs to the technical field of experimental devices for inducing mouse growth, specifically relating to an automated device for inducing hypertrophy of the ligamentum flavum in mice. Background Technology

[0002] In the field of biomedical research, inducing hypertrophy of specific tissues (such as the ligamentum flavum) in mice is a common experimental technique used to simulate related disease states in humans, thereby exploring the pathogenesis, development process, and potential treatment methods of the diseases. Such experiments usually require placing mice in a specific experimental environment and observing and recording changes in the tissues within the mice by controlling environmental factors or providing specific stimuli.

[0003] However, existing experimental devices for inducing ligamentum flavum hypertrophy in mice often lack effective wastewater filtration and purification systems, leading to direct discharge of experimental wastewater. This not only wastes valuable water resources but also potentially pollutes the environment. Furthermore, due to the lack of automated control, researchers need to frequently operate the device manually to maintain the water quality and quantity in the tank, increasing their workload and potentially causing instability in experimental conditions due to human factors, which could affect the experimental results. Therefore, the applicant proposes an automated device for inducing ligamentum flavum hypertrophy in mice to address these problems. Utility Model Content

[0004] The purpose of this invention is to provide an automated device for inducing hypertrophy of the ligamentum flavum in mice, so as to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution:

[0006] An automated device for inducing hypertrophy of the ligamentum flavum in mice, comprising:

[0007] A water tank and a water container mounted on one side of the water tank, a wastewater tank is provided on one side of the water container and the wastewater tank is fixedly installed on the adjacent outer side wall of the water tank, and multiple experimental cylinders are arranged in a linear array inside the water tank;

[0008] Each of the experimental tubes has a water filter hole penetrating its bottom and lower outer end, and each of the experimental tubes has a tube cover on its top, and the tube cover is funnel-shaped, with an iron mesh fixedly installed on the inner wall of the tube cover.

[0009] A water supply pipe is connected to one side of the water tank, and the end of the water supply pipe away from the water tank extends through the side wall of the water tank into the inside of the water tank. A sewage pipe is connected to one side of the water tank, and the end of the sewage pipe away from the water tank is connected to the inside of the sewage tank. Solenoid valves are installed on the outside of both the water supply pipe and the sewage pipe.

[0010] A filtration mechanism connected to a sewage tank and a water tank is provided on one side of the water tank. A discharge pipe is connected to the side of the sewage tank away from the filtration mechanism, and a valve is installed on the outside of the discharge pipe.

[0011] Preferably, the filtration mechanism includes a filter box disposed on one side of the sewage tank. One side of the filter box is open, and a drawer is provided inside the filter box. The top of the drawer is open, and a handle is installed on one side of the drawer. A filter screen is provided inside the drawer, and the bottom of the filter screen is fixedly installed to the bottom of the drawer. The side of the sewage tank near the filter box is connected to the drawer through an inlet pipe, and the other side of the filter box is fixedly installed to the outer wall adjacent to the water tank.

[0012] Preferably, the filtration mechanism further includes a water pump disposed on one side of the filter box, both ends of which are connected to transmission pipes. One end of the transmission pipe away from the water pump is connected to the inside of the drawer box, and the other end of the transmission pipe away from the water pump is connected to the filter box. The side of the filter box away from the water pump is connected to the inside of the water tank through an ultrafiltration membrane outlet pipe. The bottom of the water pump is fixedly installed to the adjacent outer wall of the water tank through a mounting plate.

[0013] Preferably, the filtration mechanism further includes two activated carbon plates, each with a retaining plate at its top and bottom. Each retaining plate has a slot on its side near the activated carbon plate that matches the sidewall of the activated carbon plate. The side of each retaining plate away from the activated carbon plate is fixedly installed to the inner wall adjacent to the filter box. Each of the two activated carbon plates has a slot on its top side.

[0014] Preferably, two connecting plates are symmetrically fixedly installed on one side of the top of the filter box, and the connecting plates are inverted U-shaped. A pull rod is provided inside the connecting plate. The bottom end of the pull rod passes through the top of the filter box and the adjacent card plate and is inserted into the slot. A pull block is fixedly installed through the top of the connecting plate at the top of the pull rod. A spring is sleeved on the outside of the pull rod. The two ends of the spring are fixedly connected to the bottom of the pull block and the top of the connecting plate, respectively.

[0015] Preferably, the bottom sides of the plurality of experimental tubes are fixedly installed to the bottom of the water tank by fixing blocks, the top surface of the experimental tubes are provided with slots on both sides, and the outer sides of the tube cover are fixedly installed with locking blocks that are compatible with the slots.

[0016] Preferably, a water bottle is detachably connected inside the cap and located on the wire mesh.

[0017] Compared with the prior art, the beneficial effects of this utility model are:

[0018] (1) Wastewater from the sewage tank enters the extraction box through the input pipe. The filter screen removes larger slag and impurities. The water pump pumps the filtered wastewater to the filter box, where it is filtered layer by layer by two activated carbon plates to adsorb smaller impurities. The filtered water is further purified through the ultrafiltration membrane outlet pipe to meet the reuse standard and is then discharged into the water tank to complete the circulation filtration, effectively reducing water waste. At the same time, the solenoid valve releases water and discharges wastewater in a timed and quantitative manner, achieving automation, reducing the burden of personnel operation, and improving the practicality of the device.

[0019] (2) When personnel hold the pull block and pull the pull rod, the bottom end of the pull block is separated from the activated carbon plate slot to release the positioning. At this time, the activated carbon plate can be removed from the slot for replacement or maintenance. When installing, align the activated carbon plate with the slot and slide it in. Release the pull block to allow the spring to return elastically and pull the pull block to drive the pull rod back into the slot to complete the fixation. No bolts or other fasteners are needed, which makes it convenient for personnel to quickly disassemble the activated carbon plate, reduce the operating burden, ensure that the activated carbon plate maintains a good filtration effect, and further improve the practicality of the device. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the main structure of this utility model;

[0021] Figure 2 This is a schematic diagram of the cross-sectional structure of the experimental tube of this utility model;

[0022] Figure 3 This is a schematic diagram of the transmission tube structure of this utility model;

[0023] Figure 4 This is a schematic diagram of the water pump structure of this utility model;

[0024] Figure 5 This is a schematic diagram of the activated carbon plate structure of this utility model;

[0025] In the diagram: 1. Filtration mechanism; 101. Input pipe; 102. Filter box; 103. Drawer box; 104. Filter screen; 105. Water pump; 106. Transmission pipe; 107. Filter box; 108. Ultrafiltration membrane outlet pipe; 109. Activated carbon plate; 110. Clamping plate; 111. Connecting plate; 112. Pull block; 113. Pull rod; 114. Spring; 2. Water tank; 3. Water tank; 4. Wastewater tank; 5. Experimental cylinder; 6. Cylinder cover; 7. Iron mesh; 8. Clamping block; 9. Discharge pipe; 10. Water supply pipe; 11. Sewage discharge pipe; 12. Solenoid valve. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] In the description of this utility model, it should be noted that the terms "upper," "lower," "inner," "outer," "front end," "rear end," "both ends," "one end," and "the other end," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0028] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installed," "equipped with," and "connected," etc., should be interpreted broadly. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0029] Example 1:

[0030] Please see Figures 1-5 As shown, an automated device for inducing hypertrophy of the ligamentum flavum in mice includes: a water tank 2 and a water tank 3 assembled on one side of the water tank 2. A wastewater tank 4 is provided on one side of the water tank 3, and the wastewater tank 4 is fixedly installed on the adjacent outer wall of the water tank 2. Multiple experimental tubes 5 are arranged in a linear array inside the water tank 2.

[0031] Multiple experimental cylinders 5 have water filter holes penetrating their bottom and lower outer ends. Multiple experimental cylinders 5 are equipped with cylinder covers 6 on their tops, and the cylinder covers 6 are funnel-shaped. Iron mesh 7 is fixedly installed on the inner wall of the cylinder cover 6.

[0032] A water supply pipe 10 is connected to one side of the water tank 3, and the end of the water supply pipe 10 away from the water tank 3 extends through the side wall of the water tank 2 into the interior of the water tank 2. A sewage pipe 11 is connected to one side of the water tank 2, and the end of the sewage pipe 11 away from the water tank 2 is connected to the interior of the sewage tank 4. Solenoid valves 12 are installed on the outside of both the water supply pipe 10 and the sewage pipe 11.

[0033] A filter mechanism 1 is provided on one side of the water tank 2, which is connected to the sewage tank 4 and the water tank 3. A discharge pipe 9 is connected to the side of the sewage tank 4 away from the filter mechanism 1, and a valve is installed on the outside of the discharge pipe 9.

[0034] As can be seen from the above, when it is nighttime, the solenoid valve 12 is activated and the small water pump built into the water tank 3 is activated to transfer water through the water pipe 10 to the water tank 2. The mice in the experimental tube 5 are then tested. The water that the mice come into contact with and the mice's excrement then enter the sewage tank 4 through the sewage pipe 11. The sewage tank 4 is lower than the water tank 2, so when the sewage passes through the sewage pipe 11, it will automatically flow into the sewage tank 4 due to the gravity of the water flow. Then, the wastewater is filtered and purified by the filter mechanism 1 and transferred back to the water tank 3 to complete the circulation filtration, which is convenient for subsequent use and thus reduces the waste of water resources. With the solenoid valve 12, the water tank 2 can be drained or the wastewater in the water tank 2 can be sent to the sewage tank 4 at timed and quantitative intervals, thereby achieving the effect of automation, reducing the burden of manual operation, and improving the practicality of the device. The water pump 105, the solenoid valve 12, and the small water pump built into the water tank 3 are all connected to an external controller and power supply, which is existing technology and will not be described in detail here.

[0035] For details, please refer to Figure 4 As shown, the filtration mechanism 1 includes a filter box 102 disposed on one side of the sewage tank 4. One side of the filter box 102 is open, and a drawer box 103 is provided inside the filter box 102. The top of the drawer box 103 is open, and a handle is installed on one side of the drawer box 103. A filter screen 104 is provided inside the drawer box 103, and the bottom of the filter screen 104 is fixedly installed to the bottom of the drawer box 103. The side of the sewage tank 4 near the filter box 102 is connected to the drawer box 103 through an inlet pipe 101. The other side of the filter box 102 is fixedly installed to the outer wall adjacent to the water tank 2.

[0036] As can be seen from the above, through the setup of filter box 102 and drawer box 103, the wastewater produced by the mice in the sewage tank 4 enters the drawer box 103 inside filter box 102 through the inlet pipe 101. Then, the larger slag and impurities in the wastewater are filtered out by the filter screen 104. After the experiment is completed, the personnel can hold the handle and pull out the drawer box 103 to remove the impurities, so that the drawer box 103 maintains a good filtration effect.

[0037] For details, please refer to Figure 4As shown, the filtration mechanism 1 also includes a water pump 105 disposed on one side of the filter box 102. Both ends of the water pump 105 are connected to transmission pipes 106. One end of one transmission pipe 106 away from the water pump 105 is connected to the inside of the drawer box 103, and the other end of the transmission pipe 106 away from the water pump 105 is connected to the filter box 107. The side of the filter box 107 away from the water pump 105 is connected to the inside of the water tank 3 through an ultrafiltration membrane outlet pipe 108. The bottom of the water pump 105 is fixedly installed on the adjacent outer wall of the water tank 2 through a mounting plate.

[0038] As can be seen from the above, by setting up the water pump 105, the filtered wastewater in the drawer 103 is drawn out through one of the transmission pipes 106 and then transmitted to the filter box 107 through the other transmission pipe 106. At the same time, the wastewater passes through two activated carbon plates 109 for layer-by-layer filtration, which intercepts and adsorbs smaller impurities in the wastewater, thereby achieving the effect of filtering the wastewater cleanly. Then, the filtered water is smoothly discharged through the ultrafiltration membrane outlet pipe 108. The ultrafiltration membrane itself can intercept most of the suspended solids, colloids, bacteria, viruses and other impurities in the water, thereby purifying the filtered water and achieving the effect of reuse. Finally, the water is discharged into the water tank 3 to complete the circulation filtration effect. There is no need for personnel to use a large amount of fresh water, reducing the waste of water resources. The solenoid valve 12, water pump 105 and other components are controlled by an external controller, so that the whole device achieves the effect of automation, reduces the burden of personnel operation, and improves the practicality of the device.

[0039] For details, please refer to Figure 5 As shown, the filter mechanism 1 also includes two activated carbon plates 109. Each of the two activated carbon plates 109 has a retaining plate 110 at its top and bottom. Each retaining plate 110 has a slot on the side of its side that is close to the activated carbon plate 109 that is adapted to the side wall of the activated carbon plate 109. Each retaining plate 110 is fixedly installed on the side of its side away from the activated carbon plate 109 adjacent to the inner wall of the filter box 107. Each of the two activated carbon plates 109 has a slot on the top side.

[0040] As can be seen from the above, by setting the card plate 110, the card plate 110 adapts to the side of the activated carbon plate 109 through the card slot, which can limit the activated carbon plate 109 and prevent the activated carbon plate 109 from shifting or tilting during use.

[0041] Example 2:

[0042] refer to Figure 5As shown, two connecting plates 111 are symmetrically fixedly installed on one side of the top of the filter box 107, and the connecting plates 111 are inverted U-shaped. A pull rod 113 is provided inside the connecting plate 111. The bottom end of the pull rod 113 passes through the top of the filter box 107 and the adjacent card plate 110 and is inserted into the slot. The top end of the pull rod 113 passes through the top of the connecting plate 111 and is fixedly installed with a pull block 112. A spring 114 is sleeved on the outside of the pull rod 113. The two ends of the spring 114 are fixedly connected to the bottom of the pull block 112 and the top of the connecting plate 111, respectively.

[0043] As can be seen from the above, by using the spring 114, personnel can pull the lever 113 by holding the pull block 112 to move it so that its bottom end separates from the slot and releases the positioning of the activated carbon plate 109. At this time, the pull block 112 will stretch the spring 114, and personnel can remove the activated carbon plate 109 from the slot for replacement or maintenance. During installation, the activated carbon plate 109 is aligned with the slot and slid in. Then, the pull block 112 is released, causing the spring 114 to lose tension and elastically recover, pulling the pull block 112 to drive the lever 113 back into the slot to complete the fixation. This allows personnel to quickly disassemble the activated carbon plate 109 without the need for bolts or other fasteners, reducing the burden on personnel and maintaining the good filtration effect of the activated carbon plate 109, thus improving the practicality of the device.

[0044] refer to Figure 2 As shown, the bottom sides of multiple experimental tubes 5 are fixedly installed to the bottom of the water tank 2 by fixing blocks. The top surfaces of the experimental tubes 5 are provided with slots on both sides, and the outer sides of the tube cover 6 are fixedly installed with locking blocks 8 that are compatible with the slots.

[0045] A water bottle is detachably connected inside the cap 6 and located on the wire mesh 7.

[0046] As can be seen from the above, by setting the slot and the block 8, the personnel can lock the two blocks 8 into the slot at the top of the experimental tube 5, thereby securing the tube cover 6 at the top of the experimental tube 5. This makes it convenient for the personnel to install and remove the tube cover 6 to take out the mice. At the same time, the personnel can place food or water bottles on the wire mesh 7 to facilitate feeding the mice. By inserting the straw part of the water bottle into the experimental tube 5, the mice can easily drink water.

[0047] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An automated device for inducing mouse ligamentum flavum hypertrophy, characterized by, include: A water tank (2) and a water tank (3) assembled on one side of the water tank (2). A sewage tank (4) is provided on one side of the water tank (3), and the sewage tank (4) is fixedly installed on the adjacent outer wall of the water tank (2). Multiple experimental cylinders (5) are arranged in a linear array inside the water tank (2). The bottom and lower outer end of the multiple experimental tubes (5) are all provided with water filter holes, and the top of the multiple experimental tubes (5) is provided with a tube cover (6), and the tube cover (6) is funnel-shaped. The inner wall of the tube cover (6) is fixedly installed with an iron mesh (7). A water supply pipe (10) is connected to one side of the water tank (3), and the end of the water supply pipe (10) away from the water tank (3) extends through the side wall of the water tank (2) into the interior of the water tank (2). A sewage pipe (11) is connected to one side of the water tank (2), and the end of the sewage pipe (11) away from the water tank (2) is connected to the interior of the sewage tank (4). Solenoid valves (12) are installed on the outside of both the water supply pipe (10) and the sewage pipe (11). A filter mechanism (1) is provided on one side of the water tank (2) and connected to the sewage tank (4) and the water tank (3). A discharge pipe (9) is connected to the side of the sewage tank (4) away from the filter mechanism (1), and a valve is installed on the outside of the discharge pipe (9).

2. The automated device for inducing mouse ligamentum flavum hypertrophy according to claim 1, wherein: The filtration mechanism (1) includes a filter box (102) disposed on one side of the sewage tank (4). One side of the filter box (102) is open, and a drawer box (103) is provided inside the filter box (102). The top of the drawer box (103) is open, and a handle is installed on one side of the drawer box (103). A filter screen (104) is provided inside the drawer box (103), and the bottom of the filter screen (104) is fixedly installed to the bottom of the drawer box (103). The side of the sewage tank (4) near the filter box (102) is connected to the drawer box (103) through an inlet pipe (101). The other side of the filter box (102) is fixedly installed to the outer wall adjacent to the water tank (2).

3. The automated device for inducing mouse ligamentum flavum hypertrophy according to claim 1, wherein: The filtration mechanism (1) also includes a water pump (105) disposed on one side of the filter box (102). Both ends of the water pump (105) are connected to transmission pipes (106). One end of the transmission pipe (106) away from the water pump (105) is connected to the inside of the drawer (103). The other end of the transmission pipe (106) away from the water pump (105) is connected to the filter box (107). The side of the filter box (107) away from the water pump (105) is connected to the inside of the water tank (3) through an ultrafiltration membrane outlet pipe (108). The bottom of the water pump (105) is fixedly installed to the adjacent outer wall of the water tank (2) through an mounting plate.

4. The automated device for inducing hypertrophy of the ligamentum flavum in mice according to claim 1, characterized in that: The filtration mechanism (1) also includes two activated carbon plates (109). The top and bottom of the two activated carbon plates (109) are provided with a retaining plate (110). The retaining plates (110) are provided with a slot on the side of the activated carbon plate (109) that is adapted to the side wall of the activated carbon plate (109). The retaining plates (110) are fixedly installed on the side of the filter box (107) adjacent to the side wall of the filter box (107) on the side away from the activated carbon plate (109). The top side of the two activated carbon plates (109) is provided with a slot.

5. The automated device for inducing hypertrophy of the ligamentum flavum in mice according to claim 3, characterized in that: Two connecting plates (111) are symmetrically fixedly installed on one side of the top of the filter box (107), and the connecting plates (111) are inverted U-shaped. A pull rod (113) is provided inside the connecting plate (111). The bottom end of the pull rod (113) passes through the top of the filter box (107) and the adjacent card plate (110) and is inserted into the slot. The top end of the pull rod (113) passes through the top of the connecting plate (111) and is fixedly installed with a pull block (112). A spring (114) is sleeved on the outside of the pull rod (113). The two ends of the spring (114) are fixedly connected to the bottom of the pull block (112) and the top of the connecting plate (111) respectively.

6. The automated device for inducing hypertrophy of the ligamentum flavum in mice according to claim 1, characterized in that: The bottom sides of the multiple experimental tubes (5) are fixedly installed to the bottom of the water tank (2) by fixing blocks. The top surfaces of the experimental tubes (5) are provided with slots on both sides. The outer sides of the tube cover (6) are fixedly installed with locking blocks (8) that are compatible with the slots.

7. The automated device for inducing hypertrophy of the ligamentum flavum in mice according to claim 1, characterized in that: A water bottle is detachably connected inside the cap (6) and located on the wire mesh (7).

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