Heparin sodium purification and separation equipment

By designing a multi-component heparin sodium purification and separation device, the problem of the device being limited to a single container size was solved. This enabled stable clamping of containers of different sizes and effective removal of impurities, thereby improving the applicability and purification efficiency of the device.

CN224270415UActive Publication Date: 2026-05-26NANTONG TIANRUI BIOLOGICAL TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
NANTONG TIANRUI BIOLOGICAL TECH CO LTD
Filing Date
2025-06-05
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

Existing heparin sodium purification and separation equipment can only be used with containers of a single size, and cannot be adapted to containers of different sizes, resulting in reduced equipment applicability.

Method used

A structure including a fixed frame, drive shaft, placement seat, rotating shaft, turntable, transmission groove, sliding frame and arc-shaped clamping plate is designed. The structure can clamp and fix containers of different sizes through components such as knobs, worm gears and worm wheels, and use a motor to drive the placement cylinder to rotate, combined with centrifugal force to remove insoluble matter and impurities.

Benefits of technology

It achieves stable clamping and fixation of containers of different sizes, facilitating the purification and separation of heparin sodium, and effectively removes insoluble matter and impurities from the liquid through centrifugal force.

✦ Generated by Eureka AI based on patent content.

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Abstract

This utility model discloses a heparin sodium purification and separation device, including a fixed frame, a drive shaft rotatably connected inside the fixed frame, a placement seat fixedly connected to one end of the drive shaft, a rotating shaft rotatably connected inside the placement seat, a turntable fixedly connected to one end of the rotating shaft, transmission grooves evenly spaced inside the turntable, and a sliding frame slidably connected inside the placement seat. This utility model relates to the field of separation equipment technology. This heparin sodium purification and separation device achieves the function of clamping and fixing containers of different sizes by setting a knob, worm gear, worm wheel, rotating shaft, turntable, transmission groove, push rod, sliding frame, and arc-shaped clamping plate, facilitating subsequent purification and separation of heparin sodium. By setting a motor, drive shaft, placement seat, placement cylinder, and filter cylinder, it achieves the function of driving the placement cylinder to rotate, thereby removing insoluble matter and impurities from the liquid through centrifugal force, making it convenient to use.
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Description

Technical Field

[0001] This utility model relates to the field of separation equipment technology, specifically to a heparin sodium purification and separation equipment. Background Technology

[0002] Heparin sodium is an anticoagulant that interferes with many stages of the blood clotting process, exhibiting anticoagulant effects both in vivo and in vitro. The purification and separation of heparin sodium is a complex process. First, the raw material needs to be washed to remove impurities and fats. Then, specific enzymes are used to enzymatically hydrolyze the raw material to release heparin sodium. During enzymatic hydrolysis, parameters such as pH, temperature, and time need to be controlled to achieve optimal results. After hydrolysis, insoluble substances and impurities need to be separated to obtain an enzymatic hydrolysate containing heparin sodium.

[0003] Existing heparin sodium purification and separation equipment typically only works with containers of a single size, making it inconvenient to fix containers of different sizes, reducing the equipment's applicability and making it inconvenient to use. Therefore, we propose a heparin sodium purification and separation device. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides a heparin sodium purification and separation device, which solves the problem that heparin sodium purification and separation devices can usually only be used with containers of a single size, making it inconvenient to fix containers of different sizes and reducing the applicability of the device.

[0005] To achieve the above objectives, this utility model provides the following technical solution:

[0006] A heparin sodium purification and separation device includes a fixed frame, a drive shaft rotatably connected inside the fixed frame, a placement seat fixedly connected to one end of the drive shaft, a rotating shaft rotatably connected inside the placement seat, a turntable fixedly connected to one end of the rotating shaft, transmission grooves equally spaced inside the turntable, a sliding frame slidably connected inside the placement seat, a push rod fixedly connected to one side of the sliding frame for use with the transmission grooves, an arc-shaped clamp fixedly connected to the side of the sliding frame away from the push rod, the arc-shaped clamp slidingly connected to the placement seat, a placement cylinder on the top of the placement seat, a sealing cap threadedly connected to the top of the placement cylinder, and a filter cylinder threadedly connected to the bottom of the sealing cap; the placement cylinder can be clamped and fixed by multiple sets of arc-shaped clamps, and the rotation of the placement cylinder facilitates the removal of insoluble substances and impurities from the liquid.

[0007] Preferably, one side of the arc-shaped clamp is provided with an anti-slip pad, and the top of the sealing cover is provided with a feed inlet. The anti-slip pad can provide an anti-slip effect, and the feed inlet facilitates the addition of liquid to the filter cartridge.

[0008] Preferably, a motor is fixedly connected to the bottom of the fixing frame, and the output end of the motor is fixedly connected to the drive shaft, so that the motor drives the drive shaft to rotate.

[0009] Preferably, the inner wall of the placement seat is fixedly connected with fixed rods at equal intervals, and the sliding frame is slidably connected to the fixed rods. The movement of the sliding frame can be limited by the setting of the fixed rods.

[0010] Preferably, a worm gear is rotatably connected inside the placement base, and a worm wheel that works with the worm gear is fixedly connected to the outside of the rotating shaft. A knob is fixedly connected to one end of the worm gear, and the worm gear is rotated by turning the knob. The worm gear then drives the rotating shaft to rotate through the worm wheel.

[0011] Preferably, a fixing block is fixedly connected to the outer side of the placement base, a sliding rod is slidably connected inside the fixing block, a slider is fixedly connected to one end of the sliding rod, a spring is sleeved on the outer side of the sliding rod and on one side of the slider, a locking tooth is fixedly connected to one side of the slider, and a limiting tooth ring that cooperates with the locking tooth is fixedly connected to the outer side of the knob. The slider is driven to move by the sliding rod, and the spring can drive the slider to move and reset. The slider drives the locking tooth to move and fit tightly against the limiting tooth ring, thereby locking the position of the knob and preventing accidental contact.

[0012] This invention provides a heparin sodium purification and separation device. Compared with the prior art, it has the following advantages:

[0013] 1. This heparin sodium purification and separation equipment, through the setting of knobs, worm gears, worm wheels, rotating shafts, turntables, transmission grooves, push rods, sliding frames, and arc-shaped clamps, enables the clamping and fixing of containers of different sizes, facilitating subsequent purification and separation operations of heparin sodium.

[0014] 2. This heparin sodium purification and separation equipment is equipped with a motor, drive shaft, placement seat, placement cylinder, and filter cylinder to drive the placement cylinder to rotate, thereby removing insoluble substances and impurities from the liquid through centrifugal force, making it convenient to use. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model.

[0016] Figure 2 This is a structural schematic diagram of the placement base of this utility model.

[0017] Figure 3 This is a schematic diagram of the internal structure of the placement base of this utility model.

[0018] Figure 4 This is a schematic diagram of the structure of the turntable of this utility model.

[0019] Figure 5 This is a structural schematic diagram of the fixing block of this utility model.

[0020] Figure 6 This is a structural schematic diagram of the fixing frame of this utility model.

[0021] Figure 7 This is a schematic diagram of the sealing cap of this utility model.

[0022] In the diagram: 1. Fixing frame; 2. Placement seat; 3. Arc-shaped clamp; 4. Sealing cover; 5. Placement cylinder; 6. Fixing block; 7. Knob; 8. Sliding frame; 9. Fixing rod; 10. Turntable; 11. Limiting gear ring; 12. Worm gear; 13. Transmission groove; 14. Push rod; 15. Worm wheel; 16. Rotating shaft; 17. Slide rod; 18. Slider; 19. Locking gear; 20. Spring; 21. Motor; 22. Drive shaft; 23. Filter cylinder; 24. Feed inlet. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figures 1 to 7 This utility model provides a technical solution:

[0025] A heparin sodium purification and separation device includes a fixed frame 1, a drive shaft 22 rotatably connected inside the fixed frame 1, a placement seat 2 fixedly connected to one end of the drive shaft 22, a rotating shaft 16 rotatably connected inside the placement seat 2, a turntable 10 fixedly connected to one end of the rotating shaft 16, transmission grooves 13 equally spaced inside the turntable 10, a sliding frame 8 slidably connected inside the placement seat 2, a push rod 14 cooperating with the transmission grooves 13 fixedly connected to one side of the sliding frame 8, an arc-shaped clamping plate 3 fixedly connected to the side of the sliding frame 8 away from the push rod 14, the arc-shaped clamping plate 3 slidably connected to the placement seat 2, a placement cylinder 5 provided on the top of the placement seat 2, and a threaded connection on the top of the placement cylinder 5. The sealing cover 4 has a filter cylinder 23 threadedly connected to its bottom. The drive shaft 22 drives the placement seat 2 to rotate, which in turn drives the placement cylinder 5 to rotate, allowing the liquid to enter the interior of the placement cylinder 5. Insoluble matter and impurities remain inside the filter cylinder 23, making it easier to remove insoluble matter and impurities from the liquid. The rotating shaft 16 drives the turntable 10 to rotate, which causes the transmission groove 13 to cooperate with the push rod 14. During the rotation of the turntable 10, it will squeeze and drive the push rod 14 to move. The push rod 14 drives the sliding frame 8 to slide, and the sliding frame 8 drives the arc-shaped clamping plate 3 to move. The placement cylinder 5 can be clamped and fixed by multiple sets of arc-shaped clamping plates 3.

[0026] Furthermore, an anti-slip pad is provided on one side of the arc-shaped clamping plate 3, and a feed inlet 24 is provided on the top of the sealing cover 4. The anti-slip pad can achieve the anti-slip effect, and the feed inlet 24 facilitates the addition of liquid to the filter cartridge 23.

[0027] Furthermore, a motor 21 is fixedly connected to the bottom of the mounting bracket 1, and the output end of the motor 21 is fixedly connected to the drive shaft 22, so that the drive shaft 22 is rotated by the motor 21.

[0028] Furthermore, the inner wall of the placement seat 2 is fixedly connected with fixed rods 9 at equal intervals, and the sliding frame 8 is slidably connected to the fixed rods 9. The movement of the sliding frame 8 can be limited by the setting of the fixed rods 9.

[0029] Furthermore, a worm gear 12 is rotatably connected inside the placement base 2, and a worm wheel 15 that works with the worm gear 12 is fixedly connected to the outside of the rotating shaft 16. A knob 7 is fixedly connected to one end of the worm gear 12, and the worm gear 12 is rotated by the knob 7. The worm gear 12 then drives the rotating shaft 16 to rotate through the worm wheel 15.

[0030] Furthermore, a fixing block 6 is fixedly connected to the outer side of the placement base 2, and a sliding rod 17 is slidably connected inside the fixing block 6. A slider 18 is fixedly connected to one end of the sliding rod 17. A spring 20 is sleeved on the outer side of the sliding rod 17 and on one side of the slider 18. A locking tooth 19 is fixedly connected to one side of the slider 18. A limiting tooth ring 11 that cooperates with the locking tooth 19 is fixedly connected to the outer side of the knob 7. The slider 18 is moved by the sliding rod 17, and the spring 20 can move the slider 18 to return to its original position. The slider 18 moves the locking tooth 19 to fit tightly against the limiting tooth ring 11, thereby locking the position of the knob 7 and preventing accidental contact.

[0031] Working principle:

[0032] In use, open the cover of the feed port 24, add the liquid to be purified and separated into the filter cartridge 23, and place the placement cartridge 5 on top of the placement seat 2. Pull the slide rod 17, which causes the slider 18 to move, compressing the spring 20. The slider 18 then causes the locking tooth 19 to move away from the limiting tooth ring 11, allowing the knob 7 to be rotated. The knob 7 drives the worm wheel 15 to rotate via the worm gear 12, and the worm wheel 15 drives the turntable 10 to rotate via the rotating shaft 16. This causes the transmission groove 13 to engage with the push rod 14, and during the rotation of the turntable 10, it will compress and carry... The push rod 14 moves, causing the sliding frame 8 to slide along the fixed rod 9. The sliding frame 8 then moves the arc-shaped clamping plate 3. Multiple sets of arc-shaped clamping plates 3 can clamp and fix the placement cylinder 5. The anti-slip pads provide an anti-slip effect. The motor 21 is started, and the motor 21 drives the placement seat 2 to rotate via the drive shaft 22, which in turn drives the placement cylinder 5 to rotate. This allows the liquid to enter the interior of the placement cylinder 5, while insoluble substances and impurities remain inside the filter cylinder 23, facilitating the removal of insoluble substances and impurities from the liquid and making it easy to use.

[0033] Furthermore, any content not described in detail in this specification is existing technology known to those skilled in the art.

[0034] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, the phrase "comprising an element defined as..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0035] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A heparin sodium purification and separation device, comprising a fixed frame (1), characterized in that: The fixed frame (1) is rotatably connected to a drive shaft (22), one end of which is fixedly connected to a placement seat (2). The placement seat (2) is rotatably connected to a rotating shaft (16), one end of which is fixedly connected to a turntable (10). The turntable (10) has equidistant transmission grooves (13) inside. The placement seat (2) is equidistantly slidably connected to a sliding frame (8). One side of the sliding frame (8) is fixedly connected to a push rod (14) that works with the transmission groove (13). The side of the sliding frame (8) away from the push rod (14) is fixedly connected to an arc-shaped clamp (3). The arc-shaped clamp (3) is slidably connected to the placement seat (2). The top of the placement seat (2) is provided with a placement cylinder (5). The top of the placement cylinder (5) is threadedly connected to a sealing cap (4). The bottom of the sealing cap (4) is threadedly connected to a filter cylinder (23).

2. The heparin sodium purification and separation equipment according to claim 1, characterized in that: The arc-shaped clamp (3) has an anti-slip pad on one side, and the top of the sealing cover (4) has a feed inlet (24).

3. The heparin sodium purification and separation equipment according to claim 1, characterized in that: A motor (21) is fixedly connected to the bottom of the fixed frame (1), and the output end of the motor (21) is fixedly connected to the drive shaft (22).

4. The heparin sodium purification and separation equipment according to claim 1, characterized in that: The inner wall of the placement seat (2) is fixedly connected with fixed rods (9) at equal intervals, and the sliding frame (8) is slidably connected to the fixed rods (9).

5. The heparin sodium purification and separation equipment according to claim 1, characterized in that: The placement seat (2) is rotatably connected to a worm gear (12), and the outer side of the rotating shaft (16) is fixedly connected to a worm wheel (15) that works with the worm gear (12). A knob (7) is fixedly connected to one end of the worm gear (12).

6. The heparin sodium purification and separation equipment according to claim 5, characterized in that: A fixing block (6) is fixedly connected to the outside of the placement seat (2). A slide rod (17) is slidably connected inside the fixing block (6). A slider (18) is fixedly connected to one end of the slide rod (17). A spring (20) is sleeved on the outside of the slide rod (17) and on one side of the slider (18). A locking tooth (19) is fixedly connected to one side of the slider (18). A limiting tooth ring (11) that cooperates with the locking tooth (19) is fixedly connected to the outside of the knob (7).