A liquid nitrogen granulator

Abstract

The utility model relates to pelletizer technical field especially relates to a liquid nitrogen pelletizer. Its technical scheme includes heat preservation cylinder, fixed installation on heat preservation cylinder's liquid medicine entrance and liquid nitrogen entrance, installs stirring subassembly in heat preservation cylinder, still includes the screening module of sliding installation in heat preservation cylinder inside, the screening module includes with heat preservation cylinder sliding connection's support seat, fixed mounting of screen cloth has on support seat, the screening module still includes the drive mechanism of installation on heat preservation cylinder, drive support seat and carry out periodic acceleration - deceleration movement. The utility model avoids mutual cohesion between liquid drops, leads to not forming the material particle of good form, effectively reduces the operation difficulty, improved production efficiency, has expanded the application range, for the particle that is bigger, the particle that does not meet the specified particle size standard can carry on the crushing, namely can make the material reach the particle size requirement of meeting.

Description

Technical Field

[0001] This utility model relates to the field of granulator technology, and in particular to a liquid nitrogen granulator. Background Technology

[0002] Liquid nitrogen granulators are a new type of low-temperature granulation equipment that enables rapid freezing and granulation of temperature-sensitive materials in liquid nitrogen. Combined with freeze-drying equipment, it can quickly granulate materials. This type of equipment has significant application value for high-value temperature-sensitive substances such as proteins, monoclonal antibodies, and live bacteria.

[0003] However, existing liquid nitrogen granulation equipment mainly uses a drip-feeding process, which presents the following major problems in actual production: 1) The droplet particle size is generally 0.5–5 mm. The relatively large liquid particles react violently after dripping with liquid nitrogen, resulting in irregular droplet movement. Furthermore, because liquid nitrogen is difficult to form a freezing interface quickly, the droplets adhere to each other, preventing the formation of well-shaped particles. This significantly increases operational difficulty, reduces production efficiency, and limits application scope. 2) The average particle size formed by the drip-feeding process is 0.5–3 mm, which can only meet the needs of some downstream products, such as solid beverages. It cannot meet the actual needs of more applications requiring higher uniformity, such as formula milk powder, tablets, and coating materials. 3) Due to the large particle size, heat exchange is intense during the liquid nitrogen drip-feeding process, leading to liquid nitrogen splashing and large-scale nitrogen release. This not only wastes liquid nitrogen and increases operational difficulty but also poses certain production safety hazards.

[0004] Therefore, modifying existing equipment and developing a continuous liquid nitrogen granulation device capable of producing micron-sized particles of proteins, live bacteria, and other active materials has significant technical and market value. Utility Model Content

[0005] The purpose of this invention is to address the problems existing in the background technology by proposing a liquid nitrogen granulator.

[0006] The technical solution of this utility model: a liquid nitrogen granulator, comprising an insulated cylinder, a liquid medicine inlet and a liquid nitrogen inlet fixedly installed on the insulated cylinder, wherein a stirring assembly is installed inside the insulated cylinder, and further comprising:

[0007] A screening module is slidably installed inside the insulation cylinder. The screening module includes a support base slidably connected to the insulation cylinder, on which a screen is fixedly installed. The screening module also includes a drive mechanism installed on the insulation cylinder, which drives the support base to perform periodic acceleration-deceleration motion.

[0008] Optionally, the drive mechanism includes a connecting shaft fixedly mounted on a support base, a connecting rod rotatably mounted on the connecting shaft, a crank rotatably mounted on the connecting rod, a first motor fixedly mounted on the insulation cylinder, and the output shaft of the first motor fixedly connected to the crank.

[0009] Optionally, a diversion pipe is fixedly installed on the liquid inlet, and multiple atomizing nozzles are fixedly installed at the bottom of the diversion pipe.

[0010] Optionally, the liquid nitrogen inlet is located at the upper part of the insulation cylinder, and the lower part of the insulation cylinder is provided with a discharge mechanism.

[0011] Optionally, the discharge mechanism includes a discharge pipe fixedly installed at the bottom of the insulation cylinder, a lifting spiral blade rotatably installed inside the discharge pipe, and a power component connected to the discharge pipe to drive the lifting spiral blade to rotate.

[0012] Optionally, the stirring assembly includes a rotating shaft rotatably mounted inside the insulation cylinder, a plurality of stirring blades fixedly mounted on the rotating shaft, a second motor fixedly mounted on the insulation cylinder, and the output shaft of the second motor being coaxially and fixedly connected to the rotating shaft.

[0013] Optionally, the top of the insulation cylinder is provided with an exhaust port, and a valve is installed on the exhaust port.

[0014] In summary, this application includes at least one of the following beneficial technical effects:

[0015] To prevent droplets from sticking together and failing to form well-shaped material particles, this method effectively reduces operational difficulty, improves production efficiency, and expands the application range. For larger particles that do not meet the specified particle size standard, they can be crushed to bring the material to the required particle size. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of a liquid nitrogen granulator;

[0017] Figure 2 This is a schematic diagram of the internal structure of the insulation cylinder;

[0018] Figure 3 This is a magnified view of a portion of the screening module.

[0019] Reference numerals in the attached diagram: 1. Insulated cylinder; 2. Liquid inlet; 201. Diverter pipe; 202. Atomizing nozzle; 3. Liquid nitrogen inlet; 4. Rotating shaft; 401. Stirring blade; 402. Second motor; 5. Support base; 501. Screen; 502. Connecting shaft; 503. First motor; 504. Crank; 505. Connecting rod; 6. Discharge pipe; 601. Lifting spiral blade; 7. Exhaust port; 8. Liquid nitrogen level sensor. Detailed Implementation

[0020] The technical solution of this utility model will be further described below with reference to the accompanying drawings and specific embodiments.

[0021] like Figures 1 to 3 As shown, the liquid nitrogen granulator proposed in this utility model includes an insulated cylinder 1, a liquid medicine inlet 2 and a liquid nitrogen inlet 3 fixedly installed on the insulated cylinder 1. Liquid nitrogen enters the interior of the insulated cylinder 1 through the liquid nitrogen inlet 3 and accumulates and fills the lower middle part of the insulated cylinder 1. A diversion pipe 201 is fixedly installed on the liquid medicine inlet 2, and multiple atomizing nozzles 202 are fixedly installed at the bottom of the diversion pipe 201. The liquid medicine is sprayed out through the atomizing nozzles 202 and solidifies after contacting the liquid nitrogen, and then falls downward. An exhaust port 7 is provided at the top of the insulated cylinder 1, and a valve is installed on the exhaust port 7. Since the liquid nitrogen will gradually vaporize, the gas needs to be discharged through the exhaust port 7 to ensure the normal pressure inside the insulated cylinder. A liquid nitrogen level sensor 8 for detecting the liquid nitrogen level is installed inside the insulated cylinder 1.

[0022] The upper end of the diversion pipe 201 is connected to the insulation cylinder 1 by a clamp. The height of the diversion pipe 201 can be changed by adjusting the tightness of the clamp, so that the height of the atomizing nozzle 202 is adjustable. The larger the material particles, the farther away they should be from the liquid nitrogen surface to ensure that the formed particles are regular and consistent.

[0023] The insulation cylinder 1 can be designed as a vacuum double-layer to improve the insulation effect and thus reduce the vaporization of liquid nitrogen.

[0024] like Figures 1 to 3 As shown, in this embodiment, a stirring assembly is installed inside the insulation cylinder 1. Stirring can prevent the solidified material from sticking together. Furthermore, the stirring assembly includes a rotating shaft 4 rotatably installed inside the insulation cylinder 1. Multiple stirring blades 401 are fixedly installed on the rotating shaft 4. A second motor 402 is fixedly installed on the insulation cylinder 1. The output shaft of the second motor 402 is coaxially and fixedly connected to the rotating shaft 4. By driving the rotating shaft 4 to rotate through the second motor 402, the stirring blades 401 can be rotated, thereby stirring the liquid nitrogen through the stirring blades, keeping the liquid nitrogen in a flowing state, and preventing the liquid medicine from sticking together.

[0025] like Figures 1 to 3As shown, this embodiment also includes a screening module slidably installed inside the insulation cylinder 1. The screening module includes a support base 5 slidably connected to the insulation cylinder 1, and a screen 501 is fixedly installed on the support base 5. The screening module also includes a drive mechanism installed on the insulation cylinder 1. The drive mechanism drives the support base 5 to perform periodic acceleration-deceleration motion. In order to improve the granulation accuracy and prevent the solidified particles from sticking together, the material can be screened by the screening module. When the material sticks together, the larger particle size cannot pass through the screen 501. By accelerating the screen 501, the material that cannot pass through the screen 501 can be accelerated upward and thrown out. At this time, the material is easy to contact the stirring blade 401, thereby crushing it, so that the material can meet the particle size requirements.

[0026] Furthermore, the drive mechanism includes a connecting shaft 502 fixedly mounted on the support base 5, a connecting rod 505 rotatably mounted on the connecting shaft 502, a crank 504 rotatably mounted on the connecting rod 505, and a first motor 503 fixedly mounted on the insulation cylinder 1. The output shaft of the first motor 503 is fixedly connected to the crank 504. The first motor 503 can drive the crank 504 to rotate, and the rotating crank 504 will drive the connecting rod 505 to rotate. The rotating connecting rod 505 can then push the connecting shaft 502 to move, thereby driving the support base 5 and the screen 501 to move.

[0027] Since the crank 504, connecting rod 505 and connecting shaft 502 form a crank-slider mechanism, it can be known that the movement speed of the slider, i.e. the connecting shaft 502, is sinusoidal, that is, the connecting shaft 502 performs periodic acceleration and deceleration motion.

[0028] like Figures 1 to 3 As shown in this embodiment, the lower part of the insulation cylinder 1 is provided with a discharge mechanism. The discharge mechanism includes a discharge pipe 6 fixedly installed at the bottom of the insulation cylinder 1. A lifting spiral blade 601 is rotatably installed inside the discharge pipe 6. The discharge pipe 6 is connected to a power component that drives the lifting spiral blade 601 to rotate. The power component drives the lifting spiral blade 601 to rotate, and the rotating lifting spiral blade 601 will drive the material to move outward, thereby discharging the material.

[0029] The lifting spiral blade 601 can be equipped with sieve holes, which can separate pharmaceutical particles and liquid nitrogen during the lifting process. Different sieve hole sizes can also be used to separate materials of different particle sizes.

[0030] In this embodiment, the atomized medicine solidifies into particles upon contact with liquid nitrogen and falls downwards. The second motor 402 drives the rotating shaft 4 to rotate, which in turn rotates the stirring blade 401. This stirring blade agitates the liquid nitrogen, keeping it in a flowing state and preventing the medicine from sticking together. To improve granulation accuracy and prevent the solidified particles from sticking together, the material can be screened using a sieving module. When the material sticks together, larger particles cannot pass through the screen 501. By accelerating the movement of the screen 501, the material that cannot pass through the screen 501 can be accelerated upwards and thrown out. At this point, the material is more likely to come into contact with the stirring blade 401, thereby breaking it up and ensuring that the material meets the particle size requirements.

[0031] Based on the technical solution of this utility model and the relevant teachings of the above embodiments, those skilled in the art can make various alternative combinations and improvements to the above specific embodiments using several novel optional embodiments.

Claims

1. A liquid nitrogen granulator, comprising an insulated cylinder (1), a liquid medicine inlet (2) and a liquid nitrogen inlet (3) fixedly installed on the insulated cylinder (1), wherein a stirring assembly is installed inside the insulated cylinder (1), characterized in that, Also includes: A screening module is slidably installed inside the insulation cylinder (1). The screening module includes a support seat (5) slidably connected to the insulation cylinder (1). A screen (501) is fixedly installed on the support seat (5). The screening module also includes a drive mechanism installed on the insulation cylinder (1). The drive mechanism drives the support seat (5) to perform periodic acceleration-deceleration motion.

2. The liquid nitrogen granulator according to claim 1, characterized in that, The drive mechanism includes a connecting shaft (502) fixedly mounted on a support base (5), a connecting rod (505) rotatably mounted on the connecting shaft (502), a crank (504) rotatably mounted on the connecting rod (505), and a first motor (503) fixedly mounted on the insulation cylinder (1). The output shaft of the first motor (503) is fixedly connected to the crank (504).

3. The liquid nitrogen granulator according to claim 2, characterized in that, A diversion pipe (201) is fixedly installed on the liquid inlet (2), and multiple atomizing nozzles (202) are fixedly installed at the bottom of the diversion pipe (201).

4. A liquid nitrogen granulator according to claim 3, characterized in that, The liquid nitrogen inlet (3) is located at the upper part of the insulation cylinder (1), and the lower part of the insulation cylinder (1) is provided with a discharge mechanism.

5. A liquid nitrogen granulator according to claim 4, characterized in that, The discharge mechanism includes a discharge pipe (6) fixedly installed at the bottom of the insulation cylinder (1), a lifting spiral blade (601) is rotatably installed inside the discharge pipe (6), and the discharge pipe (6) is connected to a power component that drives the lifting spiral blade (601) to rotate.

6. A liquid nitrogen granulator according to claim 5, characterized in that, The stirring assembly includes a rotating shaft (4) rotatably installed inside the heat-insulating cylinder (1), a plurality of stirring blades (401) are fixedly installed on the rotating shaft (4), and a second motor (402) is fixedly installed on the heat-insulating cylinder (1). The output shaft of the second motor (402) is coaxially and fixedly connected to the rotating shaft (4).

7. A liquid nitrogen granulator according to claim 6, characterized in that, The top of the insulation cylinder (1) is provided with an exhaust hole (7), and a valve is installed on the exhaust hole (7).

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