An ultrafiltration centrifuge tube

Abstract

The utility model provides a kind of ultrafiltration centrifugal tube, including filter, inner tube, outer tube;The filter is arranged in inner tube;The inner tube sleeve is set in outer tube;The inner tube and filter are integrally formed using the same material joint mode. By ingeniously combining filter and inner tube, the existing technique sleeve mode under the action of centrifugal force, leading to membrane and tube body falling off, resulting in the situation of protein leakage is solved;At the same time, the problem of multiple components of the existing ultrafiltration tube and the problem of introducing the third medium are solved.

Description

Technical Field

[0001] This utility model relates to the field of ultrafiltration centrifuge tube technology, specifically, to an ultrafiltration centrifuge tube. Background Technology

[0002] Currently, the ultrafiltration centrifuge tube industry generally employs a multi-structure approach, using ultrasonic welding or adhesive bonding to connect different components. This often leads to cracks in the ultrafiltration centrifuge tube under centrifugal force, damaging the overall structure; or the sealing effect is limited, resulting in leaks under centrifugal force; some methods use the deformation of rubber elastomers to achieve a sealing effect, but this introduces a third substance, inevitably affecting the filtration quality of the ultrafiltration tube under centrifugal force. Therefore, it is particularly important to innovate an ultrafiltration centrifuge tube that can reduce the number of parts and improve the overall structural stability. Utility Model Content

[0003] To address the shortcomings of existing technologies, the purpose of this invention is to provide an ultrafiltration centrifuge tube that effectively combines the inner tube and the filter, achieving true one-piece molding. This avoids the structural instability issues caused by multi-structure mechanical bonding methods, while ensuring the consistency of the overall material and preventing the impact caused by the introduction of various substances.

[0004] An ultrafiltration centrifuge tube according to the present invention includes a filter, an inner tube, and an outer tube;

[0005] The filter is disposed inside the inner tube;

[0006] The inner tube is fitted inside the outer tube;

[0007] The inner tube and the filter are integrally formed by joining the same material.

[0008] Furthermore, the filter includes a filter membrane and a filter element;

[0009] The filter membrane is placed on one side of the filter sheet;

[0010] The filter element is provided with several flow channels to support the filter membrane;

[0011] A flow guide hole is provided below the flow guide groove.

[0012] Furthermore, the part where the filter sheet connects to the inner tube has a concave-convex structure.

[0013] Furthermore, the concave-convex structure is a stepped structure.

[0014] Furthermore, the filter is provided with at least two filter elements and a filter membrane.

[0015] Furthermore, the inner tube has an inverted conical design, and the filter is located at the V-shaped bottom of the inner tube; the filter membrane is positioned facing inwards from the inner tube.

[0016] Furthermore, a liquid storage space is left between the guide hole and the inside of the inner tube.

[0017] Furthermore, the filter has a positioning structure on its outer side, which can play a positioning role when the filter and the inner tube are integrally formed.

[0018] Furthermore, the outer tube is also equipped with a cap. After the inner tube is placed into the inner cavity of the outer tube, the cap is put on, and the tube can be placed in a centrifuge for operation.

[0019] Furthermore, the inner tube and the filter are integrally formed by injection molding.

[0020] Furthermore, the positioning structure is designed with at least two raised positioning points, which are symmetrically arranged on the outside of the filter element, so that the filter is fixed in the mold by the positioning points and prevents it from shifting in the mold.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] 1. By cleverly combining the filter and inner tube into one unit, the problem of protein leakage caused by the membrane and tube detaching under centrifugal force in existing sleeve-type technologies is solved.

[0023] 2. By organically combining the filter and the inner tube, the ultrafiltration centrifuge tube solves the problems of multiple components in existing ultrafiltration tubes and the problem of introducing a third medium in practical use. Attached Figure Description

[0024] Other features, objects, and advantages of this invention will become more apparent from the following detailed description of non-limiting embodiments with reference to the accompanying drawings:

[0025] Figure 1 This is a schematic diagram of the inner tube and filter of the ultrafiltration centrifuge tube of this utility model;

[0026] Figure 2 This is a schematic diagram of the overall structure of the utility model ultrafiltration centrifuge tube.

[0027] The diagram shows: 10 filter, 20 inner tube, 30 outer tube, 101 filter membrane, 102 filter sheet, 103 concave-convex structure, 104 vent hole, 105 positioning structure, 106 liquid storage space, 112 flow guide groove, 122 flow guide hole, and 301 cover. Detailed Implementation

[0028] The present invention will now be described in detail with reference to specific embodiments. These embodiments will help those skilled in the art to further understand the present invention, but do not limit the present invention in any way. It should be noted that those skilled in the art can make several changes and improvements without departing from the concept of the present invention. These all fall within the protection scope of the present invention.

[0029] In this embodiment, an ultrafiltration centrifuge tube includes a filter 10, an inner tube 20, and an outer tube 30. The filter 10 is disposed inside the inner tube 20, and the inner tube 20 and the filter 10 are integrally formed by injection molding. The inner tube 20 is sleeved inside the outer tube 30. The filter 10 includes a filter membrane 101 and a filter element 102, with the filter membrane 101 placed on one side of the filter element 102. The filter element 102 is provided with several guide grooves 112 to support the filter membrane 101. Guide holes 122 are provided below the guide grooves 112, through which the filtered filtrate flows into the outer tube 30 under centrifugal force. The portion where the filter 10 connects to the inner tube 20 has a concave-convex structure 103, which increases the contact area and makes the connection between the filter 10 and the inner tube 20 more secure. Specifically, the concave-convex structure 103 of the filter 10 is designed as a multi-layered stepped structure with a longer middle and shorter ends. This allows the filter 10 and the inner tube 20 to be more firmly connected during secondary injection molding. At the same time, the stepped structure also prevents damage to the filter membrane 101 during the hot-melt process.

[0030] The filter membrane 101 adopts a double-layer structure, consisting of a filter layer and a substrate layer. The filter layer is used for material filtration, while the substrate layer is mainly used to improve the processability of the membrane material, for bonding between the membrane material and plastic, to increase the centrifugal force of the membrane material itself, and to improve the durability of the filter layer.

[0031] The inner tube 20 has an inverted conical design. The filter 10 is located at the V-shaped bottom of the inner tube 20, with the filter membrane 101 facing inwards. A guide hole 122 is located at the bottom of the filter 10, through which the filtered liquid flows out. A liquid storage space 106 is left between the guide hole 122 and the inside of the inner tube 20 to receive the filtered sample, preventing sample loss or drying out after excessive centrifugation. A positioning structure 105 is provided on the outside of the filter 10, which can play a positioning role when the filter 10 and the inner tube 20 are integrally formed. An exhaust port 104 is also provided at the opening of the inner tube 20, which can play a role in balancing the air pressure when the ultrafiltration tube is operating in the centrifuge.

[0032] Specifically, the filter 10 may be provided with multiple filter elements 102 and filter membranes 101. In this embodiment, the filter 10 is provided with two filter elements 102 and filter membranes 101. The two filter elements 102 are symmetrically arranged in a V-shape at the bottom of the inner tube 20.

[0033] The outer tube 30 is also equipped with a cover 301. After the inner tube 20 is placed into the inner cavity of the outer tube 30, the cover 301 is put on before it is put into the centrifuge for operation.

[0034] Instructions for use: Add the sample solution to the inner tube 20, insert the inner tube 20 into the outer tube 30, cover with the cap 301, and place in a centrifuge for centrifugation. Under the action of centrifugal force, the solution in the inner tube 20 passes through the filter membrane 101, achieving desalting and concentration, thereby replacing different solutions and screening for different molecular weights.

[0035] The specific manufacturing process of the ultrafiltration centrifuge tube in this embodiment includes the following steps:

[0036] Step 1: Weld the filter membrane 101 onto the filter element 102 to form the filter 10. Specifically, the filter element 102 is pre-formed from plastic and has a hollow membrane placement area. Hot-melt welding at a temperature of 100℃-180℃ is used to weld the filter membrane onto the filter element. Specifically, the filter element 102 has welding strips. When the filter membrane 101 comes into contact with the welding strips, the welding strips melt into a narrow plane, covering the perimeter of the filter membrane 101, achieving a tight weld between the filter element 102 and the filter membrane 101. This results in better adhesion between the filter membrane 101 and the filter element 102, increases the tear resistance of the filter membrane 101, and avoids the "membrane vibration effect" that can occur with ultrasonic welding, which could damage the filter membrane 101.

[0037] Step 2: Fix the filter 10 under the mold, which has the same shape as the inner tube 20. Specifically, the side of the filter 10 with the positioning structure 105 is pressed against and positioned in the placement groove of the mold by the fixing structure 105, fixing the filter 10 under the mold and preventing it from shifting within the mold. The placement groove is a recess of the same size as one side of the filter 10, and it has a positioning groove that nests with the positioning structure 105. During positioning, the positioning structure 105 nests within the positioning groove, achieving the positioning of the filter 10 and preventing it from shifting within the mold.

[0038] The filter is designed with two raised positioning points to fix the filter in the mold and prevent it from shifting in the mold.

[0039] Step 3: The mold is injection molded at a temperature between 170℃ and 280℃ using an injection molding machine, with the injection molding time controlled between 1 and 3 seconds. Specifically, the concave-convex structure 103 of the filter 10 is designed as a multi-layered stepped structure with a longer middle and shorter ends. This design allows for a stronger connection between the filter 10 and the inner tube 20 during secondary injection molding, while the stepped structure also prevents damage to the filter membrane 101 during the hot-melt process.

[0040] Injection molding overmolding utilizes the molten state of the plastic material to fix the filter 10 in the mold of the inner tube, achieving one-piece molding. This improves the product's integrity, overall strength, and simplifies its structure. Specifically, ABS, PP, PMMA, and other plastic materials can be used for injection molding, and the material used can be consistent with that of the filter 10. In this embodiment, both the filter 10 and the inner tube 10 are made of more compatible ABS plastic, and the injection molding temperature is between 190℃ and 220℃, which significantly improves the overall strength of the product. By using injection molding overmolding to integrally mold the filter 10 and the inner tube 20, not only is the "membrane vibration effect" caused by conventional ultrasonic welding, which damages the critical filter membrane structure, avoided, but it also avoids the drawbacks of introducing a third substance through the use of rubber or other adhesives, thus preventing the ultrafiltration centrifuge tube from affecting its stability under centrifugal force.

[0041] Step 4: After injection molding is completed, cool for 15-40 seconds and demold to obtain an integrally formed inner tube 20 with filter 10.

[0042] Compared to existing ultrafiltration centrifuge tubes, the ultrafiltration centrifuge tubes of this product show a significant improvement in performance under different centrifugal forces, as shown in the table below:

[0043] product Centrifugal force of angular rotor time Is there a crack in the inner tube? Is the inner tube broken? This product 9000g 30 minutes none none Product A 9000g 30 minutes yes none Product B 9000g 30 minutes yes yes

[0044] As can be seen from the table above, the ultrafiltration centrifuge tubes manufactured using the above process can withstand stronger centrifugal forces compared to most products currently on the market. Under the same intensity of centrifugal force, the inner tube of this product remains intact, which means it can clearly withstand stronger centrifugal forces. This effectively solves the problem in existing products where cracks occur under centrifugal force due to the manufacturing process itself, leading to damage to the overall structure.

[0045] In the description of this application, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0046] The specific embodiments of this utility model have been described above. It should be understood that this utility model is not limited to the specific embodiments described above, and those skilled in the art can make various changes or modifications within the scope of the claims, which do not affect the substantive content of this utility model. Unless otherwise specified, the embodiments and features described in this application can be arbitrarily combined with each other.

Claims

1. An ultrafiltration centrifuge tube, characterized in that, Includes filter (10), inner tube (20), and outer tube (30); The filter (10) is disposed inside the inner tube (20); The inner tube (20) is fitted inside the outer tube (30); The filter (10) includes a filter membrane (101) and a filter sheet (102); The filter membrane (101) is placed on one side of the filter sheet (102); The filter sheet (102) is provided with a plurality of flow channels (112) to support the filter membrane (101). A flow guide hole (122) is provided below the flow guide groove (112); The inner tube (20) and the filter (10) are integrally formed by joining the same material.

2. The ultrafiltration centrifuge tube according to claim 1, characterized in that, The part where the filter (102) connects to the inner tube (20) has a concave-convex structure (103).

3. The ultrafiltration centrifuge tube according to claim 2, characterized in that, The concave-convex structure (103) is a stepped structure.

4. The ultrafiltration centrifuge tube according to claim 1, characterized in that, The filter (10) is provided with at least two filter elements (102) and a filter membrane (101).

5. The ultrafiltration centrifuge tube according to claim 1, characterized in that, The inner tube (20) is designed in an inverted cone shape, and the filter (10) is located at the bottom V-shaped part of the inner tube (20); the filter membrane (101) is arranged facing the inside of the inner tube (20).

6. The ultrafiltration centrifuge tube according to claim 1, characterized in that, A liquid storage space (106) is left between the flow guide hole (122) and the inside of the inner tube (20).

7. The ultrafiltration centrifuge tube according to claim 1, characterized in that, The filter (10) is provided with a positioning structure (105) on the outside, which can play a positioning role when the filter (10) and the inner tube (20) are integrally formed.

8. The ultrafiltration centrifuge tube according to claim 1, characterized in that, The outer tube (30) is also provided with a cover (301).

9. The ultrafiltration centrifuge tube according to claim 1, characterized in that, The inner tube (20) and the filter (10) are integrally formed by injection molding.

10. The ultrafiltration centrifuge tube according to claim 7, characterized in that, The positioning structure (105) is designed with at least two raised positioning points, which are symmetrically arranged on the outside of the filter (102), so that the filter (10) is fixed in the mold by the positioning points to prevent it from shifting in the mold.

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