A medicine raw material crushing and screening integrated device

Abstract

The application relates to the technical field of pharmaceutical raw material production, in particular to a pharmaceutical raw material crushing and screening integrated equipment, which comprises a support, one side of the support is provided with a stirring and screening mechanism, the top of the stirring and screening mechanism is provided with a crushing mechanism, the top of the crushing mechanism is provided with a feeding hopper, and the bottom of the stirring and screening mechanism is provided with a discharging hopper. The utility model discloses a stirring cylinder, a hollow stirring rod, a heating and pumping box and other components. The mutual cooperation between the circulating pump in the heating and pumping box and the bidirectional heat conduction pipes in the hollow stirring rod enables the heating and pumping box to drive the heat conduction oil through the circulating pump, forms bidirectional circulation paths in the outer layer and the inner layer heat conduction pipes of the hollow stirring rod, uniformly heats the pharmaceutical raw materials in the stirring cylinder, and the device can heat the screened pharmaceutical raw materials through the heat circulation assembly, and the crushing efficiency is improved.

Description

Technical Field

[0001] This application relates to the field of pharmaceutical raw material production technology, and in particular to an integrated equipment for crushing and screening pharmaceutical raw materials. Background Technology

[0002] In the field of pharmaceutical raw material production, traditional crushing, sieving, and mixing processes often require multiple machines to complete in stages. This not only occupies a large amount of production space but also suffers from problems such as poor process coordination and low efficiency. Moreover, a single heating method makes it difficult to accurately control the temperature, which can easily lead to uneven heating of raw materials and affect drug quality. At the same time, ordinary mixing equipment is insufficient for grinding raw materials, making it difficult to meet the stringent requirements of modern pharmaceuticals for the fineness and uniformity of raw materials.

[0003] A search revealed Chinese Patent Publication No. CN222816933U, which discloses an integrated equipment for pulverizing and sieving pharmaceutical raw materials, relating to the field of pharmaceutical production technology. This invention includes a first support frame, a second support frame, a processing tank, and a discharge limiting frame. The processing tank is rotatably engaged with one side of the first support frame, and two grinding tubes are threaded through and engaged with one end of the processing tank. Each grinding tube has ventilation openings at both ends. A second support frame is located on one side of the first support frame, and a rotating frame is engaged with one end of the second support frame. Multiple fine screens are threaded through and engaged on the outer circumference of the rotating frame. The discharge limiting frame is attached to the bottom of the rotating frame, and a pressure sensing component is engaged with the bottom of the discharge limiting frame. This invention, by incorporating the first support frame, the second support frame, the processing tank, and the discharge limiting frame, solves the problems of difficulty in controlling the amount of each size of pharmaceutical particles during multi-stage pulverization, low efficiency in cooling the equipment casing, and the need for air filtration when using pumped-in cold air for cooling.

[0004] Regarding the aforementioned technologies, the inventors have discovered the following drawbacks: the device lacks a heating component and relies solely on the ventilation openings of the grinding tube for temperature regulation, making it difficult to achieve uniform heating of the raw materials and potentially affecting the physicochemical properties of the drug raw materials. Furthermore, the equipment relies on the grinding tube to crush the raw materials, lacking a targeted stirring and grinding structure, thus failing to perform refined processing of the raw materials and potentially resulting in uneven particle size. Utility Model Content

[0005] In order to solve the problems mentioned in the background art, this application provides an integrated equipment for pulverizing and screening pharmaceutical raw materials.

[0006] This application provides an integrated equipment for pulverizing and sieving pharmaceutical raw materials, which adopts the following technical solution: An integrated equipment for pulverizing and sieving pharmaceutical raw materials includes a support frame, a stirring and sieving mechanism on one side of the support frame, a pulverizing mechanism on the top of the stirring and sieving mechanism, a feed funnel on the top of the pulverizing mechanism, and a discharge funnel at the bottom of the stirring and sieving mechanism; the stirring and sieving mechanism includes a stirring drum for processing raw materials, a heat circulation component for heating raw materials, and a stirring component for stirring and grinding raw materials. The heat circulation component includes a heating pump box on the left and right sides of the stirring drum, a hollow stirring rod with built-in heat transfer oil, and a chuck for sealing the stirring drum. The hollow stirring rod is divided into an outer annular array of heat transfer pipes and an inner annular array of heat transfer pipes, wherein the outer and inner heat transfer pipes are respectively provided with one-way valves in opposite directions. The heating pump box is equipped with a circulation pump. The chuck seals both ends of the stirring drum, fixes the position of the hollow stirring rod, and prevents heat transfer oil leakage and raw material overflow.

[0007] Optionally, the stirring assembly includes a bearing side cover for fixing the reduction gearbox and servo motor, a rotating shaft fixedly connected to the output end of the reduction gearbox, a positioning plate for fixing the stirring scraper, and a stirring scraper for stirring and grinding. The stirring scraper is arc-shaped and its shape fits the inner wall of the stirring cylinder. The bearing side cover fixes the reduction gearbox and servo motor, supports the rotation of the rotating shaft, and ensures the stability of the stirring assembly.

[0008] Optionally, in the heat circulation assembly, the one-way valve of the outer heat-conducting pipe flows clockwise, and the one-way valve of the inner heat-conducting pipe flows counterclockwise, forming a bidirectional heat-conducting oil circulation path.

[0009] Optionally, a servo motor is provided on one side of the crushing mechanism to drive the crushing blades inside the crushing mechanism; the top of the crushing mechanism is connected to the feed funnel, and the bottom is connected to the mixing drum; the discharge funnel is fixedly installed at the bottom of the mixing drum.

[0010] Optionally, the rotating shaft is fixedly connected to one side of the positioning plate, and the rotating shaft is movably installed on one side of the bearing side cover. The positioning plate fixes the position of the stirring scraper to ensure that it moves in contact with the inner wall of the stirring drum.

[0011] Optionally, the distance between the stirring scraper and the inner wall of the stirring cylinder is 1mm, and the side of the stirring scraper near the inner wall of the stirring cylinder is provided with an abrasive surface, which is a frosted surface.

[0012] Optionally, a detachable screen is provided between the discharge funnel and the stirring drum for screening the pulverized drug raw materials.

[0013] Optionally, the chucks are symmetrically arranged at both ends of the mixing drum to seal the mixing drum and fix the position of the hollow mixing rod.

[0014] In summary, this application includes the following beneficial technical effects:

[0015] 1. This utility model, by setting up components such as a stirring drum, a hollow stirring rod, and a heating pump box, and through the cooperation between the circulating pump in the heating pump box and the bidirectional heat conduction pipes in the hollow stirring rod, enables the heating pump box to drive the heat transfer oil through the circulating pump, forming a bidirectional circulation path in the outer and inner heat conduction pipes of the hollow stirring rod, so as to uniformly heat the drug raw materials in the stirring drum. Thus, this device can pre-treat and heat the screened drug raw materials through the heat circulation component, thereby improving the pulverization efficiency.

[0016] 2. This utility model, by setting up components such as a rotating shaft, a positioning plate, and a stirring scraper, and through the mutual cooperation between the rotating shaft, the positioning plate, and the stirring scraper, enables the rotating shaft to drive the stirring scraper through the positioning plate to stir and grind the drug raw materials in the stirring drum. The arc-shaped design and frosted surface of the stirring scraper can adhere to the drum wall to scrape off the material and refine the particles, thereby achieving the effect of this device being able to fully stir and refine the screened drug raw materials through the stirring components. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure in an embodiment of this application;

[0018] Figure 2 This is a partial structural diagram of an embodiment of this application;

[0019] Figure 3 This is a partial structural diagram of the stirring and screening mechanism in an embodiment of this application;

[0020] Figure 4 This is a schematic diagram of the partial structure installation of the stirring and screening mechanism in the embodiments of this application.

[0021] Reference numerals: 1. Support; 2. Stirring and screening mechanism; 201. Stirring drum; 202. Bearing side cover; 203. Rotating shaft; 204. Heating pump box; 205. Chuck; 206. Hollow stirring rod; 207. Positioning plate; 208. Stirring scraper; 209. Abrasive surface; 3. Crushing mechanism; 4. Feed funnel; 5. Discharge funnel. Detailed Implementation

[0022] The following is in conjunction with the appendix Figure 1-4 This application will be described in further detail.

[0023] This application discloses an integrated equipment for pulverizing and screening pharmaceutical raw materials.

[0024] like Figures 1 to 3 As shown, an integrated pharmaceutical raw material pulverizing and sieving device includes a support frame 1. A stirring and sieving mechanism 2 is arranged on one side of the support frame 1. The stirring and sieving mechanism 2 includes a stirring drum 201 for processing raw materials, a heat circulation component for heating the raw materials, and a stirring component for stirring and grinding the raw materials. The heat circulation component includes a heating pump box 204 arranged on the left and right sides of the stirring drum 201, a hollow stirring rod 206 with built-in heat-conducting oil, and a chuck 205 for sealing the stirring drum 201. The hollow stirring rod 206 is divided into an outer annular array of heat-conducting pipes and an inner annular array of heat-conducting pipes. One-way valves in opposite directions are respectively installed inside the outer and inner heat-conducting pipes. A circulation pump is installed inside the heating pump box 204. The heat circulation component drives the heat-conducting oil to flow bidirectionally in the inner and outer heat-conducting pipes of the hollow stirring rod 206 through the circulation pump, continuously providing uniform and stable heat to the raw materials in the stirring drum 201 to meet the temperature requirements for processing different pharmaceutical raw materials.

[0025] like Figure 2 and Figure 3 As shown, the mixing assembly includes a bearing side cover 202 for fixing the reduction gearbox and servo motor, a rotating shaft 203 fixedly connected to the output end of the reduction gearbox, a positioning disk 207 for fixing the mixing scraper 208, and the mixing scraper 208 for mixing and polishing. The mixing scraper 208 is arc-shaped and its shape conforms to the inner wall of the mixing cylinder 201. The rotating shaft 203 is fixedly connected to one side of the positioning disk 207 and movably mounted on one side of the bearing side cover 202. Driven by the servo motor, the mixing assembly drives the positioning disk 207 and the arc-shaped mixing scraper 208 to rotate via the rotating shaft 203. The scraper, which conforms to the cylinder wall, can both fully mix the raw materials and polish them, improving the uniformity and fineness of the raw material processing.

[0026] like Figure 1 As shown, a crushing mechanism 3 is installed at the top of the stirring and screening mechanism 2, a feed hopper 4 is installed at the top of the crushing mechanism 3, and a discharge hopper 5 is installed at the bottom of the stirring and screening mechanism 2. In the heat circulation assembly, the one-way valve of the outer heat-conducting pipe flows clockwise, and the one-way valve of the inner heat-conducting pipe flows counterclockwise, forming a bidirectional heat-conducting oil circulation path. The crushing mechanism 3 can initially crush the raw materials conveyed by the feed hopper, the bidirectional heat-conducting oil circulation path makes the heat distribution more even, and the discharge hopper 5 provides a discharge channel for the processed raw materials, connecting to the subsequent production process.

[0027] like Figure 1As shown, a servo motor is installed on one side of the pulverizing mechanism 3 to drive the pulverizing blades inside the pulverizing mechanism 3; the top of the pulverizing mechanism 3 is connected to the feed funnel 4, and the bottom is connected to the mixing drum 201; the discharge funnel 5 is fixedly installed at the bottom of the mixing drum 201. A detachable screen is installed between the discharge funnel 5 and the mixing drum 201 for screening the pulverized drug raw materials. The servo motor drives the pulverizing blades to rotate at high speed, breaking large pieces of raw materials into particles. The detachable screen can screen the particle size of the pulverized raw materials to ensure that the material entering the mixing drum 201 meets the processing requirements and is easy to clean and maintain.

[0028] like Figures 2 to 4 As shown, the distance between the stirring scraper 208 and the inner wall of the stirring cylinder 201 is 1mm. An abrasive surface 209, which is abrasive, is provided on the side of the stirring scraper 208 closest to the inner wall of the stirring cylinder 201. Chucks 205 are symmetrically arranged at both ends of the stirring cylinder 201 to seal the stirring cylinder 201 and fix the position of the hollow stirring rod 206. The abrasive surface enhances the grinding effect of the stirring scraper 208 on the raw materials. The chuck 205 seals the stirring cylinder 201 and fixes the hollow stirring rod 206, ensuring the sealing and stability of the thermal circulation system, while also maintaining the precise position of the stirring scraper 208 during rotation, thus improving processing quality.

[0029] Example

[0030] Laboratory R&D Scene

[0031] When developing new drugs in the laboratory, researchers pour the raw materials to be processed into the equipment through the feed funnel 4. After the raw materials enter the crushing mechanism 3, a servo motor on one side of the crushing mechanism 3 drives the internal crushing blades to initially crush the raw materials. The initially crushed raw materials enter the stirring drum 201 of the stirring and screening mechanism 2 from the bottom of the crushing mechanism 3.

[0032] At this point, the researchers activated the thermal circulation and stirring components. The circulation pump inside the heating pump box 204 started working, driving the built-in heat transfer oil to circulate in the hollow stirring rod 206. Since the one-way valve of the outer heat transfer pipe flows clockwise and the one-way valve of the inner heat transfer pipe flows counterclockwise, the heat transfer oil forms a bidirectional circulation path, uniformly heating the raw materials in the stirring drum 201. Simultaneously, the reduction gearbox and servo motor fixed to the bearing side cover 202 drive the rotating shaft 203 to rotate, and the rotating shaft 203 drives the positioning disk 207 and the stirring scraper 208 fixed on it to rotate. The arc-shaped stirring scraper 208, which fits against the inner wall of the stirring drum 201, stirs the raw materials at a 1mm interval, and its abrasive surface 209 further polishes the raw materials.

[0033] After being stirred, ground, and heated, the raw materials are discharged through the discharge funnel 5 at the bottom of the stirring drum 201. A detachable screen is set between the discharge funnel 5 and the stirring drum 201 to screen the pulverized drug raw materials. Researchers can select a screen with an appropriate mesh size according to experimental needs to obtain raw materials that meet the requirements for subsequent experiments.

[0034] The implementation principle of the integrated drug raw material pulverization and sieving equipment in this application embodiment is as follows:

[0035] First, the raw material enters the crushing mechanism 3 through the feed hopper 4 at the top of the equipment. The servo motor inside drives the crushing blades to rotate at high speed, which initially crushes the block or granular raw material. The crushed material falls into the mixing and screening mechanism 2 below through the bottom outlet of the crushing mechanism 3 to complete the coarse processing stage. In this process, the particle size of the raw material is reduced to a range suitable for subsequent mixing and processing through the mechanical shearing and impact action of the crushing blades.

[0036] Secondly, after the material enters the mixing drum 201, the heating pump boxes 204 on both sides start the circulation pump, driving the built-in heat transfer oil to flow into the hollow stirring rod 206. Since the outer heat transfer pipe one-way valve flows clockwise and the inner one-way valve flows counterclockwise, a two-way heat transfer oil circulation path is formed. The heat is evenly transferred to the inner wall of the mixing drum 201 through the hollow rod to heat and soften the material. At the same time, the servo motor of the stirring component drives the rotating shaft 203 to rotate through the reduction gear box. The positioning disk 207 fixed on the rotating shaft 203 drives the arc-shaped stirring scraper 208 to rotate against the drum wall, fully mixing the heated material to prepare for subsequent fine processing.

[0037] Next, as the stirring scraper 208 continues to rotate, its abrasive surface 209 (1mm away from the inner wall) near the cylinder wall generates friction and grinding action on the material, further breaking up the protruding or agglomerated parts on the surface of the particles. At the same time, the heat transfer oil circulation system maintains a constant temperature environment inside the cylinder, avoiding local overheating and deterioration of the raw materials due to frictional heat generation, or reducing the hardness of the material by heating, thereby improving grinding efficiency.

[0038] Next, the processed material falls to the bottom of the mixing drum 201, where a detachable screen between it and the discharge hopper 5 screens the material: particles that meet the set particle size pass through the screen into the discharge hopper 5 and are discharged as finished products; larger particles are retained by the screen and continue to remain in the mixing drum 201 to participate in the next round of mixing and grinding. The screen aperture can be changed according to production needs to ensure that the particle size of the finished product is accurate and controllable.

[0039] Finally, qualified materials are collected through discharge funnel 5 and enter subsequent processes. After the equipment is stopped, the hollow stirring rod 206 and stirring scraper 208 can be removed by disassembling the screen and loosening the chucks 205 at both ends. The inner wall of the stirring drum 201 and each component can be cleaned or repaired. The sealing design of the heat circulation system (chuck 205 fixes the hollow rod and one-way valve prevents heat transfer oil leakage) ensures safe and convenient maintenance and meets the high requirements of the pharmaceutical industry for equipment cleanliness and maintenance efficiency.

[0040] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. An integrated equipment for pulverizing and sieving pharmaceutical raw materials, comprising a support frame (1), characterized in that: A stirring and screening mechanism (2) is provided on one side of the support (1), a crushing mechanism (3) is provided on the top of the stirring and screening mechanism (2), a feeding funnel (4) is provided on the top of the crushing mechanism (3), and a discharge funnel (5) is provided on the bottom of the stirring and screening mechanism (2). The stirring and screening mechanism (2) includes a stirring drum (201) for processing raw materials, a heat circulation component for heating raw materials, and a stirring component for stirring and grinding raw materials. The heat circulation component includes a heating pump box (204) provided on the left and right sides of the stirring drum (201), a hollow stirring rod (206) with built-in heat transfer oil, and a chuck (205) for sealing the stirring drum (201). The hollow stirring rod (206) is divided into an outer ring array of heat-conducting pipes and an inner ring array of heat-conducting pipes. The outer heat-conducting pipes and the inner heat-conducting pipes are respectively provided with one-way valves in opposite directions. The heating pump box (204) is provided with a circulation pump.

2. The integrated pharmaceutical raw material pulverizing and sieving equipment according to claim 1, characterized in that: The stirring assembly includes a bearing side cover (202) for fixing the reduction gearbox and servo motor, a rotating shaft (203) fixedly connected to the output end of the reduction gearbox, a positioning plate (207) for fixing the stirring scraper (208), and a stirring scraper (208) for stirring and polishing. The stirring scraper (208) is arc-shaped and its shape fits the inner wall of the stirring cylinder (201).

3. The integrated equipment for pulverizing and sieving pharmaceutical raw materials according to claim 1, characterized in that: In the heat circulation assembly, the one-way valve of the outer heat pipe flows clockwise, while the one-way valve of the inner heat pipe flows counterclockwise, forming a bidirectional heat-guiding oil circulation path.

4. The integrated pharmaceutical raw material pulverizing and sieving equipment according to claim 1, characterized in that: A servo motor is provided on one side of the crushing mechanism (3) to drive the crushing blades inside the crushing mechanism (3); the top of the crushing mechanism (3) is connected to the feed funnel (4), and the bottom is connected to the stirring cylinder (201); the discharge funnel (5) is fixedly installed at the bottom of the stirring cylinder (201).

5. The integrated pharmaceutical raw material pulverizing and sieving equipment according to claim 2, characterized in that: The rotating shaft (203) is fixedly connected to one side of the positioning disk (207), and the rotating shaft (203) is movably installed on one side of the bearing side cover (202).

6. The integrated pharmaceutical raw material pulverizing and sieving equipment according to claim 2, characterized in that: The distance between the stirring scraper (208) and the inner wall of the stirring cylinder (201) is 1 mm. The stirring scraper (208) has an abrasive surface (209) on the side close to the inner wall of the stirring cylinder (201). The abrasive surface (209) is a frosted surface.

7. The integrated pharmaceutical raw material pulverizing and sieving equipment according to claim 1, characterized in that: A detachable screen is provided between the discharge funnel (5) and the stirring drum (201) for screening the pulverized drug raw materials.

8. The integrated equipment for pulverizing and sieving pharmaceutical raw materials according to claim 1, characterized in that: The chucks (205) are symmetrically arranged at both ends of the mixing drum (201) to seal the mixing drum (201) and fix the position of the hollow mixing rod (206).

Images