A high-throughput cassette kit precentrifuge

Abstract

The utility model belongs to centrifuge technical field, and disclose a kind of high flux cassette kit pre-centrifuge, including box and the placing structure in the middle part of box, and the ejection structure below placing structure, the placing structure includes the disc rotatingly connected in the inside of box by bearing and four placing slots in circular array distribution, and blood group card rotor is assembled in the inside of placing slot, the inner wall of box and below the disc are equipped with servo motor for driving disc rotation, the placing slot inner wall is equipped with round hole, through the design of placing structure, four groups of placing slot and blood group card rotor form collaborative positioning structure, reagent card can be embedded in placing slot by standardization interface, and mechanical locking is realized by rotor card slot, constructs rigid connection system, servo motor as power source, driving turntable realizes fixed shaft rotation, utilize centrifugal field to make sample in reagent card complete centrifugal separation.

Description

Technical Field

[0001] This utility model relates to the field of centrifuge technology, and in particular to a high-throughput pre-centrifuge for cassette reagent kits. Background Technology

[0002] In the fields of biomedicine and clinical diagnostics, high-throughput cartridge reagent kits have seen continuous expansion in application due to their high efficiency and convenience. However, traditional centrifuges struggle to meet the processing needs of high-throughput cartridge reagent kits, exhibiting problems such as low throughput, complex operation, and poor adaptability. For example, traditional centrifuges can only process a small number of kits at a time, resulting in extremely low efficiency during large-scale nucleic acid testing or disease screening. Furthermore, different kit specifications are difficult to interchange, requiring frequent replacement of parts and cumbersome operation. Against this backdrop, high-throughput cartridge reagent pre-centrifuges have emerged. By optimizing the design of the centrifuge rotor and cartridge holder structure, they can process multiple cartridge reagent kits simultaneously, significantly improving sample processing efficiency and fully meeting the needs of large-scale testing and experiments. Simultaneously, their excellent compatibility allows them to adapt to various cartridge reagent kit specifications without frequent replacement of equipment parts. In addition, this pre-centrifuge features precise speed, time, and temperature control functions, enabling precise adjustment of centrifugation parameters according to the experimental requirements of different reagent kits, ensuring the consistency and reliability of centrifugation results and laying a solid quality foundation for subsequent sample testing and analysis.

[0003] In the process of realizing this invention, the inventors discovered that the prior art has at least the following problems: most cassette centrifuges are only equipped with a single material bin structure. Due to the physical volume and spatial layout of the material bin, the number of reagent cards that can be carried at one time has an inherent upper limit. When facing large-scale testing scenarios that lead to a significant increase in the number of cards used, due to the limited single-bin single-time processing capacity, it is necessary to achieve full sample processing through multiple batches of cyclic centrifugation operations. This will inevitably lead to an increase in the total time of pre-centrifugation operations, making it difficult to meet the actual needs for timeliness and efficiency improvement in high-throughput testing scenarios.

[0004] Therefore, the aforementioned technical problems need to be solved. Utility Model Content

[0005] In order to overcome the shortcomings of the existing technology, the basic technical solution proposed by this utility model is: a high-throughput card reagent pre-centrifuge, including a box and a placement structure located in the middle of the box, and a top-out structure located below the placement structure;

[0006] The placement structure includes a disc rotatably connected to the inside of the housing via bearings and four placement slots arranged in a circular array, as well as a blood type card rotor assembled inside the placement slots. The inner wall of the placement slots is provided with circular holes.

[0007] Preferably, a servo motor for driving the disk to rotate is installed on the inner wall of the housing and below the disk.

[0008] Preferably, the ejection structure includes two limiting frames installed at the bottom of the disc and a rotating disc slidably connected inside the limiting frames, as well as four ejection rods installed at the top of the rotating disc that are adapted to the circular holes.

[0009] Preferably, the front of the housing is provided with a movable groove, and the inner wall of the movable groove is rotatably connected to a connecting rod.

[0010] Preferably, the inner wall of the connecting rod has a circular opening, and a rotating rod is installed inside the circular opening. The rotating rod is rotatably connected to the inner wall of the movable groove.

[0011] Preferably, one end of the rotating rod extends through the movable groove to the outside of the housing, and the other end of the rotating rod is located below the rotating disk.

[0012] The beneficial effects of this utility model are:

[0013] Through the design of the placement structure, the four sets of placement slots and the blood type card rotor form a cooperative positioning structure. The reagent card can be embedded into the placement slot through a standardized interface and mechanically locked through the rotor card slot to build a rigid connection system. The servo motor serves as the power source to drive the turntable to achieve fixed-axis rotation and use the centrifugal force field to complete the centrifugal separation of the sample in the reagent card.

[0014] Meanwhile, in conjunction with the design of the ejection structure, the lever transmission principle is adopted. By pressing one end of the connecting rod, mechanical displacement is generated, and torque is transmitted with the rotating rod as the fulcrum. This drives the turntable assembly to move vertically under the constraint of the limit frame. The ejection column contacts the bottom surface of the blood type card rotor through the through-hole structure, forming a uniform lifting force, making it more convenient to pick up the reagent card. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the overall structure of Embodiment 1 of the present invention. Figure 1 ;

[0016] Figure 2 This is a schematic diagram of the overall structure of the present utility model. Figure 2 ;

[0017] Figure 3 This is a top view of the present invention;

[0018] Figure 4 This is a schematic diagram of the overall cross-sectional structure of this utility model;

[0019] Figure 5 This is a schematic diagram of the overall structure of the present utility model. Figure 3 ;

[0020] Figure 6 This is a schematic diagram of the placement structure and the ejection structure of this utility model.

[0021] Explanation of reference numerals in the attached figures:

[0022] 1. Box body; 2. Placement structure; 21. Disc; 22. Placement slot; 23. Blood type card rotor; 24. Servo motor; 3. Ejection structure; 31. Limit frame; 32. Rotary disk; 33. Ejection rod; 34. Connecting rod; 35. Rotating rod. Detailed Implementation

[0023] The following will be combined with the appendix Figure 1 To be continued Figure 6 The technical solutions in the embodiments of this utility model are clearly and completely described. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. Based on the embodiments of this utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of this utility model.

[0024] It should be noted that, in the embodiments of this utility model, the directions shown in the accompanying drawings shall prevail, such as front and back. Figure 1 For the sake of accuracy, the specific details should be as follows: Figure 1 The left side is the front. Figure 1 The right side is the rear; at the same time, as Figure 2 As shown, the horizontal direction is roughly defined as left and right, and the vertical direction is defined as up and down. If a specific orientation changes, the directional indication will also change accordingly.

[0025] Example 1

[0026] Please see Figure 1 - Figure 6 As shown, this embodiment provides a high-throughput card-type reagent kit pre-centrifuge, including a box body 1 and a placement structure 2 located in the middle of the box body 1, and a top-out structure 3 located below the placement structure 2. The box body 1 is equipped with a box lid, which needs to be closed during centrifugation.

[0027] The placement structure 2 includes a disc 21 rotatably connected to the inside of the housing 1 via bearings and four placement slots 22 arranged in a circular array, as well as a blood type card rotor 23 assembled inside the placement slots 22. The inner wall of the placement slots 22 has a circular hole. The blood type card rotor 23 is an existing structure that is already quite mature in the field, so it will not be described in detail.

[0028] This invention addresses the limitation of existing cassette centrifuges in terms of physical volume due to their single-material-bin structure, which limits the number of reagent cards that can be carried at one time. In large-scale testing scenarios, multiple batches of cyclic centrifugation operations are required, leading to an increase in the total pre-centrifugation time and making it difficult to meet the timeliness and efficiency requirements of high-throughput testing. Therefore, through the design of the placement structure 2, four sets of placement slots 22 and blood type card rotor 23 form a cooperative positioning structure. The reagent card can be embedded into the placement slot 22 through a standardized interface and mechanically locked through the rotor slot, constructing a rigid connection system. The servo motor 24 serves as the power source, driving the turntable to achieve fixed-axis rotation and using the centrifugal force field to complete the centrifugal separation of the sample in the reagent card.

[0029] Meanwhile, in conjunction with the design of the ejection structure 3, the lever transmission principle is adopted. By pressing one end of the connecting rod 34, mechanical displacement is generated, and torque is transmitted with the rotating rod 35 as the fulcrum. The turntable assembly is driven to move vertically under the constraint of the limiting frame 31. The ejection column contacts the bottom surface of the blood type card rotor 23 through the through-hole structure, forming a uniform lifting force, making it more convenient to pick up the reagent card.

[0030] Example 2

[0031] like Figure 2 - Figure 6 As shown, a servo motor 24 for driving the rotation of the disk 21 is installed on the inner wall of the housing 1 and below the disk 21. The ejection structure 3 includes two limiting frames 31 installed at the bottom of the disk 21 and a rotating disk 32 slidably connected inside the limiting frames 31, as well as four ejection rods 33 adapted to the circular holes installed on the top of the rotating disk 32. A movable groove is opened on the front of the housing 1. A connecting rod 34 is rotatably connected to the inner wall of the movable groove. A circular opening is opened on the inner wall of the connecting rod 34. A rotating rod 35 is installed inside the circular opening. The rotating rod 35 is rotatably connected to the inner wall of the movable groove. One end of the rotating rod 35 extends through the movable groove to the outside of the housing 1, and the other end of the rotating rod 35 is located below the rotating disk 32.

[0032] It is worth noting that the connecting rod 34 and the rotating rod 35 form a lever structure. By pressing one end of the connecting rod 34 externally (the lever arm), the rotating disk 32 is driven to move upward with a small force using the mechanical lever principle. This design converts the manual pressure of the operator into the vertical lifting force of the ejector rod 33, reducing the intensity of manual operation. It is especially suitable for scenarios where samples are frequently loaded and unloaded. Furthermore, as shown in the attached figure, the movable groove restricts the rotation position of the rotating rod 35, reducing the problem of excessive rotation and failure to return to the original position. The limiting frame 31 forms a rigid constraint on the rotating disk 32 in the vertical direction, ensuring that the ejector rod 33 moves only along the axis of the circular hole, avoiding damage or jamming of the reagent card caused by deviation.

[0033] Work steps:

[0034] First, the reagent card is embedded into the placement slot 22 through a standardized interface. The slot structure of the blood type card rotor 23 is used to achieve mechanical locking, so that the reagent card and the placement structure 2 form a rigid connection system. Multiple placement slots 22 arranged in a circular array can load multiple sets of reagent cards simultaneously, significantly improving the sample processing capacity per batch. After loading, the servo motor 24 drives the disk 21 to rotate on a fixed axis as a power source. The motor precisely controls the speed and, under the action of centrifugal force, the sample in the reagent card completes phase separation. After the centrifugation operation is completed, the operator presses one end of the connecting rod 34 in the movable slot on the front of the box 1. The lever structure formed by the connecting rod 34 and the rotating rod 35 forms a torque transmission with the rotating rod 35 as the fulcrum. Using the mechanical lever principle, the manual pressure is converted into a vertical lifting force, driving the rotating disk 32 to move upward in the vertical direction under the rigid constraint of the limiting frame 31. At this time, the ejection rod 33, which is adapted to the circular hole at the top of the rotating disk 32, contacts the bottom surface of the blood type card rotor 23 through the through-hole structure and forms a uniform lifting force, pushing the reagent card out synchronously.

[0035] Based on the disclosure and teachings of the above specification, those skilled in the art can make changes and modifications to the above embodiments. Therefore, this utility model is not limited to the specific embodiments disclosed and described above, and some modifications and changes to this utility model should also fall within the protection scope of the claims of this utility model. Furthermore, although some specific terms are used in this specification, these terms are only for convenience of explanation and do not constitute any limitation on this utility model.

Claims

1. A high-throughput cartridge reagent pre-centrifuge, characterized in that: It includes a box (1) and a placement structure (2) located in the middle of the box (1), and an ejection structure (3) located below the placement structure (2). The placement structure (2) includes a disc (21) rotatably connected to the inside of the housing (1) via bearings and four placement slots (22) arranged in a circular array, as well as a blood type card rotor (23) assembled inside the placement slots (22), and the inner wall of the placement slots (22) is provided with a circular hole.

2. The high-throughput cartridge reagent pre-centrifuge according to claim 1, characterized in that: A servo motor (24) for driving the disk (21) to rotate is installed on the inner wall of the housing (1) and below the disk (21).

3. A high-throughput cartridge reagent pre-centrifuge according to claim 2, characterized in that: The ejection structure (3) includes two limiting frames (31) installed at the bottom of the disc (21) and a rotating disc (32) slidably connected inside the limiting frames (31), as well as four ejection rods (33) installed on the top of the rotating disc (32) that are adapted to the circular holes.

4. A high-throughput cartridge reagent pre-centrifuge according to claim 3, characterized in that: The front of the box (1) is provided with a movable groove, and the inner wall of the movable groove is rotatably connected to a connecting rod (34).

5. A high-throughput cartridge reagent pre-centrifuge according to claim 4, characterized in that: The inner wall of the connecting rod (34) has a circular opening, and a rotating rod (35) is installed inside the circular opening. The rotating rod (35) is rotatably connected to the inner wall of the movable groove.

6. A high-throughput cartridge reagent pre-centrifuge according to claim 5, characterized in that: One end of the rotating rod (35) extends through the movable groove to the outside of the box (1), and the other end of the rotating rod (35) is located below the rotating disk (32).

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