Anti-pollution tubercle drug sensitivity detection sealed culture tube

Abstract

The utility model discloses a kind of anti-pollution's tubercle drug sensitivity detection sealed incubation tube, it is related to incubation tube technical field, including outer tube, the upper of outer tube is equipped with sealing cover, the outside of outer tube is equipped with sealing mechanism, the sealing mechanism includes two pull components, connecting component and sealing component, pull component, connecting component and sealing component are mutually matched and used, pull component includes rotating block, rotating block is fixedly connected at the outside of outer tube, rotating block is rotatably connected with rotating shaft in its inside.The utility model discloses a kind of anti-pollution's tubercle drug sensitivity detection sealed incubation tube, through the sealing mechanism being set, can be to incubation tube multiple layer fixed and sealed, avoid because of mistake and pour and lead to sample leakage in incubation tube inside, improve the sealing property of incubation tube, also avoid the problem that sealing effect can be influenced possibly because of temperature change or material deformation when long-term culture, structure is simple, and practicality is stronger.

Description

Technical Field

[0001] This utility model relates to the field of culture tube technology, and in particular to a contamination-proof sealed culture tube for tuberculosis drug sensitivity testing. Background Technology

[0002] The tuberculosis drug susceptibility testing sealed culture tube is a contamination-proof culture device specifically designed for drug susceptibility testing of Mycobacterium tuberculosis. It consists of a double-layer tube body, an intelligent sealing cap, and a leak-proof structure. It is used to culture drug samples for tuberculosis drug testing. Currently, most culture tubes used in tuberculosis drug susceptibility testing adopt a simple plug or screw cap design, which has poor sealing performance.

[0003] Based on the aforementioned technologies, the applicant believes that during transportation or experimental operations, the tube cap is prone to loosening due to vibration or collision, leading to leakage of culture medium or aerosols. This not only pollutes the environment but may also pose a biosafety risk to laboratory personnel. Traditional tube caps lack a stable fixing structure, and during long-term culture, temperature changes or material deformation may affect the sealing effect. To address the above problems, we have launched a pollution-proof sealed culture tube for tuberculosis drug sensitivity testing. Utility Model Content

[0004] This utility model discloses a pollution-proof sealed culture tube for tuberculosis drug sensitivity testing, aiming to solve the technical problem that the tube cap is easily loosened due to vibration or collision, leading to leakage of culture medium or aerosol, which not only pollutes the environment but may also pose a biosafety risk to laboratory personnel. Traditional tube caps lack a stable fixing structure, and the sealing effect may be affected by temperature changes or material deformation during long-term culture.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A contamination-resistant sealed culture tube for tuberculosis drug sensitivity testing includes an outer tube with a sealing cap at the top. A sealing mechanism is located on the outer side of the outer tube. The sealing mechanism includes two pulling components, a connecting component, and a sealing component. These components cooperate with each other. Each pulling component includes a rotating block fixedly connected to the outer side of the outer tube. A rotating shaft is rotatably connected inside the rotating block, and a connecting plate is fixedly connected to the outer side of the rotating shaft. A rubber pulling strip is fixedly connected to the top of the connecting plate, and a pulling plate is fixedly connected to the top of the rubber pulling strip. The sealing cap has symmetrically arranged slots on its top, which cooperate with the pulling plates.

[0007] The sealing mechanism allows for multi-layer fixation and sealing of the culture tube, preventing sample leakage due to accidental contact or tipping. This improves the sealing performance of the culture tube and avoids the problem of temperature changes or material deformation affecting the sealing effect during long-term culture. The structure is simple and highly practical.

[0008] In a preferred embodiment, the connecting assembly includes a fixing block fixedly connected to the outside of the outer tube, an adjusting shaft rotatably connected inside the fixing block, and an L-shaped connecting rod fixedly connected to the outside of the adjusting shaft, the L-shaped connecting rod being fixedly connected to the outer side of the sealing cap.

[0009] The fixing block and adjusting shaft of the connecting component allow the L-shaped connecting rod to be angled, ensuring the fit between the sealing cover and the outer tube, preventing the cover from loosening due to external vibration, improving the stability of the overall structure, and making it suitable for operation scenarios with frequent opening and closing.

[0010] In a preferred embodiment, the sealing assembly includes a sealing disc fixedly connected to the top of the sealing cover, a sealing groove being formed at the bottom of the sealing cover, annular grooves being symmetrically formed inside the sealing groove, and rubber strips being symmetrically fixedly connected to the outer side of the outer tube, the rubber strips and the annular grooves cooperating with each other.

[0011] The sealing assembly's sealing disc and sealing groove work together, combined with the elastic seal of the annular groove and rubber strip, to form a double leak-proof structure. This effectively prevents the leakage of culture medium or aerosols, reduces the risk of infection for laboratory personnel, and enhances the sealing performance for long-term culture.

[0012] In a preferred embodiment, an inner tube is fixedly connected to the inside of the outer tube, and the inside of the inner tube is provided with a conical sedimentation tank.

[0013] The inner tube design makes the culture environment more stable, and the conical sedimentation tank facilitates sample sedimentation and collection, reduces sample disturbance during stirring or movement, improves detection accuracy, and reduces the risk of aerosol generation.

[0014] In a preferred embodiment, a 2-3 mm buffer cavity is formed between the outer tube and the inner tube.

[0015] A 2-3 mm buffer cavity is formed between the outer tube and the inner tube, which ensures gas exchange (such as oxygen and carbon dioxide permeation) and reduces the impact of external temperature fluctuations on the culture environment, thereby improving the growth stability of Mycobacterium tuberculosis.

[0016] In a preferred embodiment, the outer tube is made of transparent polycarbonate with a thickness of 1.5-2 mm, and the inner tube is made of breathable polytetrafluoroethylene with 0.2-0.4 μm gas exchange micropores in its wall.

[0017] The outer tube is made of transparent polycarbonate, which makes it easy to observe the culture status, while the inner tube is made of breathable polytetrafluoroethylene to ensure gas exchange while blocking microbial contamination, making the culture environment closer to the ideal conditions and improving the accuracy of drug sensitivity testing.

[0018] The contamination-resistant sealed culture tube for tuberculosis drug sensitivity testing provided by this utility model has the following advantages:

[0019] Firstly, the sealing mechanism can fix and seal the culture tube in multiple layers, preventing leakage of the sample inside the culture tube due to accidental contact or tipping, thus improving the sealing performance of the culture tube. It also avoids the problem that the sealing effect may be affected by temperature changes or material deformation during long-term culture. The structure is simple and highly practical.

[0020] Secondly, the inner tube design makes the culture environment more stable. The conical sedimentation tank facilitates sample sedimentation and collection, reduces sample disturbance during stirring or movement, improves detection accuracy, and reduces the risk of aerosol generation. A 2-3 mm buffer cavity is formed between the outer and inner tubes, which ensures gas exchange (such as oxygen and carbon dioxide permeation) while reducing the impact of external temperature fluctuations on the culture environment, thus improving the growth stability of Mycobacterium tuberculosis. The outer tube is made of transparent polycarbonate, which facilitates observation of the culture status, while the inner tube is made of breathable polytetrafluoroethylene, which ensures gas exchange while blocking microbial contamination, making the culture environment closer to ideal conditions and improving the accuracy of drug sensitivity testing. Attached Figure Description

[0021] Figure 1 This is a three-dimensional schematic diagram of a contamination-proof sealed culture tube for tuberculosis drug sensitivity testing proposed in this utility model.

[0022] Figure 2 This is a three-dimensional cross-sectional schematic diagram of a contamination-proof sealed culture tube for tuberculosis drug sensitivity testing proposed in this utility model.

[0023] Figure 3 This is a three-dimensional schematic diagram of the sealing cap of a tuberculosis drug sensitivity testing sealed culture tube that is designed to prevent contamination, as proposed in this utility model.

[0024] Figure 4 This is a three-dimensional schematic diagram of the sealing cap of a tuberculosis drug sensitivity testing sealed culture tube that is designed to prevent contamination, as proposed in this utility model.

[0025] Figure 5 This invention proposes a contamination-proof sealed culture tube for tuberculosis drug sensitivity testing. Figure 1 A magnified diagram of point A.

[0026] Figure 6 This invention proposes a contamination-proof sealed culture tube for tuberculosis drug sensitivity testing. Figure 2 The enlarged diagram of point B.

[0027] In the attached diagram: 1. Outer tube; 2. Sealing cap; 31. Rotating block; 32. Rotating shaft; 33. Connecting plate; 34. Rubber pull strip; 35. Pulling plate; 36. Slot; 41. Fixing block; 42. Adjusting shaft; 43. L-shaped connecting rod; 44. Sealing disc; 45. Sealing groove; 46. Annular groove; 47. Rubber strip; 5. Inner tube; 6. Conical sedimentation tank. Detailed Implementation

[0028] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. The components of the embodiments of this application described and marked in the accompanying drawings can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of this application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but merely represents selected embodiments of this application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without inventive effort are within the scope of protection of this application.

[0029] The present invention discloses a contamination-proof sealed culture tube for tuberculosis drug sensitivity testing, which is mainly used in culture tube applications.

[0030] Reference Figures 1-6 A contamination-resistant sealed culture tube for tuberculosis drug sensitivity testing includes an outer tube 1, a sealing cap 2 at the top of the outer tube 1, and a sealing mechanism on the outside of the outer tube 1. The sealing mechanism includes two pulling components, a connecting component, and a sealing component, which work together. The pulling components include a rotating block 31, which is fixedly connected to the outside of the outer tube 1. A rotating shaft 32 is rotatably connected inside the rotating block 31, and a connecting plate 33 is fixedly connected to the outside of the rotating shaft 32. A rubber pulling strip 34 is fixedly connected to the top of the connecting plate 33, and a pulling plate 35 is fixedly connected to the top of the rubber pulling strip 34. The top of the sealing cap 2 has symmetrically opened slots 36, which work together with the pulling plates 35. The connecting component includes a fixing block 41, which is fixedly connected to the outside of the outer tube 1. An adjusting shaft 42 is rotatably connected inside the fixing block 41, and an L-shaped connecting rod 43 is fixedly connected to the outside of the adjusting shaft 42. The L-shaped connecting rod 43 is fixedly connected to the outer side of the sealing cap 2. The sealing assembly includes a sealing disc 44, which is fixedly connected to the top of the sealing cover 2. A sealing groove 45 is provided at the bottom of the sealing cover 2. An annular groove 46 is symmetrically provided inside the sealing groove 45. A rubber strip 47 is symmetrically fixedly connected to the outside of the outer tube 1. The rubber strip 47 and the annular groove 46 cooperate with each other.

[0031] In this embodiment: the sealed culture tube achieves stable closure through the cooperation of the groove 36 of the sealing cap 2 and the pull plate 35, and the L-shaped connecting rod 43 of the connecting assembly ensures that the sealing cap 2 and the outer tube 1 fit tightly together.

[0032] When opening is required, pull the rubber pull strip 34 to disengage the pull plate 35 from the inside of the slot 36, and then rotate the shaft 32 to smoothly lift the sealing cover 2, avoiding aerosol diffusion caused by sudden opening. The sealing disc 44 and the annular groove 46 of the sealing groove 45, together with the rubber strip 47, form a double seal to prevent sample leakage. Through the set sealing mechanism, the culture tube can be fixed and sealed in multiple layers, avoiding sample leakage inside the culture tube due to accidental bumping or tilting, improving the sealing performance of the culture tube, and avoiding the problem that the sealing effect may be affected by temperature changes or material deformation during long-term culture. The structure is simple and highly practical.

[0033] In the above technical solution, considering that the tube cap is prone to loosening due to vibration or impact, leading to leakage of culture medium or aerosols, which not only pollutes the environment but may also pose a biosafety risk to laboratory personnel, traditional tube caps lack a stable fixing structure, and the sealing effect may be affected by temperature changes or material deformation during long-term culture. To solve these problems, the specific operation is as follows:

[0034] Reference Figures 1-6 In a preferred embodiment, an inner tube 5 is fixedly connected inside the outer tube 1, and a conical sedimentation tank 6 is provided inside the inner tube 5. A buffer cavity of 2-3 mm is formed between the two tubes, the outer tube 1 and the inner tube 5. The outer tube 1 is made of transparent polycarbonate material with a thickness of 1.5-2 mm, and the inner tube 5 is made of breathable polytetrafluoroethylene material, with 0.2-0.4 μm gas exchange micropores on the tube wall.

[0035] In this embodiment: the inner tube 5 makes the culture environment more stable, the conical sedimentation tank 6 facilitates sample sedimentation and collection, reduces sample disturbance during stirring or moving, improves detection accuracy, and reduces the risk of aerosol generation. A 2-3 mm buffer cavity is formed between the outer tube 1 and the inner tube 5, which ensures gas exchange (such as oxygen and carbon dioxide permeation) and reduces the impact of external temperature fluctuations on the culture environment, thus improving the growth stability of Mycobacterium tuberculosis. The outer tube 1 is made of transparent polycarbonate material, which makes it easy to observe the culture status. The inner tube 5 is made of breathable polytetrafluoroethylene to ensure gas exchange while blocking microbial contamination, making the culture environment closer to ideal conditions and improving the accuracy of drug sensitivity detection.

[0036] Working principle: The sealed culture tube achieves stable closure through the cooperation of the groove 36 of the sealing cap 2 and the pull plate 35. The L-shaped connecting rod 43 of the connecting component ensures that the sealing cap 2 and the outer tube 1 are tightly fitted.

[0037] When it is necessary to open, pull the rubber pull strip 34 to disengage the pull plate 35 from the inside of the slot 36, and then rotate the shaft 32 to lift the sealing cover 2 smoothly, avoiding aerosol diffusion caused by sudden opening. The sealing disc 44 and the annular groove 46 of the sealing groove 45 cooperate with the rubber strip 47 to form a double seal to prevent sample leakage. The ventilated micropores of the inner tube 5 allow gas exchange and block contaminants. The conical sedimentation tank 6 reduces sample disturbance, and the buffer cavity maintains environmental stability. The overall structure ensures good growth of tuberculosis bacteria while preventing contamination.

[0038] The above description is merely a preferred embodiment of this utility model, but the protection scope of this utility model is not limited thereto. The substitutions may be replacements of some structures, devices, or method steps, or they may be complete technical solutions. Equivalent substitutions or modifications made based on the technical solution and inventive concept of this utility model should all be covered within the protection scope of this utility model.

Claims

1. A contamination-proof sealed culture tube for tuberculosis drug sensitivity testing, comprising an outer tube (1), characterized in that: A sealing cap (2) is provided above the outer tube (1), and a sealing mechanism is provided on the outside of the outer tube (1). The sealing mechanism includes two pulling components, a connecting component and a sealing component, which are used in cooperation with each other. The pulling assembly includes a rotating block (31), which is fixedly connected to the outside of the outer tube (1). A rotating shaft (32) is rotatably connected inside the rotating block (31). A connecting plate (33) is fixedly connected to the outside of the rotating shaft (32). A rubber pulling strip (34) is fixedly connected to the top of the connecting plate (33). A pulling plate (35) is fixedly connected to the top of the rubber pulling strip (34). A slot (36) is symmetrically opened on the top of the sealing cover (2). The slot (36) and the pulling plate (35) cooperate with each other.

2. The anti-contamination sealed culture tube for tuberculosis drug sensitivity testing according to claim 1, characterized in that: The connecting assembly includes a fixing block (41), which is fixedly connected to the outside of the outer tube (1). An adjusting shaft (42) is rotatably connected inside the fixing block (41). An L-shaped connecting rod (43) is fixedly connected to the outside of the adjusting shaft (42). The L-shaped connecting rod (43) is fixedly connected to the outer side of the sealing cover (2).

3. The anti-contamination sealed culture tube for tuberculosis drug sensitivity testing according to claim 1, characterized in that: The sealing assembly includes a sealing disc (44), which is fixedly connected to the top of the sealing cover (2). The bottom of the sealing cover (2) is provided with a sealing groove (45), and the interior of the sealing groove (45) is symmetrically provided with annular grooves (46). Rubber strips (47) are symmetrically fixedly connected to the outside of the outer tube (1). The rubber strips (47) and the annular grooves (46) cooperate with each other.

4. The anti-contamination sealed culture tube for tuberculosis drug sensitivity testing according to claim 1, characterized in that: The inner tube (5) is fixedly connected to the inner tube (1), and the inner tube (5) is provided with a conical sedimentation tank (6).

5. The anti-contamination sealed culture tube for tuberculosis drug susceptibility testing according to claim 1, characterized in that: A 2-3 mm buffer cavity is formed between the two tubes, the outer tube (1) and the inner tube (5).

6. The anti-contamination sealed culture tube for tuberculosis drug sensitivity testing according to claim 4, characterized in that: The outer tube (1) is made of transparent polycarbonate with a thickness of 1.5-2mm, and the inner tube (5) is made of breathable polytetrafluoroethylene with 0.2-0.4μm gas exchange micropores on the tube wall.

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