A device for purifying a pharmaceutical intermediate

Abstract

The utility model relates to a kind of medical intermediates purification processing device, especially suitable for Chinese herbal medicine extraction.The device includes cylindrical tank and openable top cover, bottom cover.Cylindrical tank outer wall is attached to spiral heating pipe, and the outer side of heating pipe is covered with shell to form closed cavity, its air inlet end is connected with air inlet pipe through upper groove on the top of shell, and air outlet end is connected with air outlet pipe through lower outlet on the bottom, and sealing ring is arranged on the outer side of top cover to form sealed passage with upper groove.Cylindrical tank inner wall is uniformly distributed with layered mi-shaped rods to prevent drug powder from sticking to wall.Bottom cover is locked by diamond-shaped rod through the cooperation of diamond-shaped hole of L-shaped fixing rod of support table and bottom connecting rod.Working time, drug powder and water are indirectly heated by high-temperature steam in tank through heating pipe, and medicinal ingredients are outputted by condensation purification through top cover exhaust pipe with steam.The utility model improves heat efficiency by spiral heating pipe, layered rods ensure uniform heating, diamond-shaped rod mechanism realizes quick disassembly of bottom cover, and solves the problems of low extraction rate and inconvenient waste residue cleaning in traditional process.

Description

Technical Field

[0001] This utility model belongs to the technical field of pharmaceutical intermediate processing equipment, specifically relating to a pharmaceutical intermediate purification and processing equipment. Background Technology

[0002] Pharmaceutical intermediates are chemical raw materials or products used in drug synthesis processes. They can be produced in ordinary chemical plants, and as long as they reach a certain level, they can be used in drug synthesis. Currently, pharmaceutical intermediate purification equipment generally faces three major technical bottlenecks:

[0003] (1) Uneven heating leads to low extraction rate: Traditional jacketed heating tanks have a large diameter, and the powder is easily compacted under gravity after water is added. The heat conduction efficiency in the central area is insufficient, resulting in incomplete release of active ingredients.

[0004] (2) Low efficiency of waste cleaning: The mainstream equipment uses flange bolts to fix the bottom cover. Each disassembly requires turning 12-16 bolts, which is time-consuming and labor-intensive. In addition, the bolts are prone to rust and jamming under high temperature conditions.

[0005] (3) Insufficient thermal energy utilization: The existing equipment adopts a direct steam exhaust design and does not utilize waste heat, and the effective components are lost with the waste gas;

[0006] In summary, to address the issues of uneven heating, inefficient slag removal, and excessive energy consumption mentioned above, we provide a pharmaceutical intermediate purification and processing apparatus. Utility Model Content

[0007] In order to overcome the problems in the background art, the present invention provides a pharmaceutical intermediate purification and processing device.

[0008] To achieve the above objectives, this utility model is implemented through the following technical solution:

[0009] A pharmaceutical intermediate purification and processing apparatus mainly includes a cylindrical tank; the tank has an openable top cover and an openable bottom cover, the top cover has a discharge port and an exhaust pipe, the exhaust pipe is connected to a steam output pipe via a flange; a spiral heating tube is fitted to the outer wall of the tank, the heating tube is covered by an outer shell, the inner side of the outer shell and the outer wall of the tank form a sealed cavity, the heating tube is housed in the cavity; the bottom of the outer shell has a lower outlet, and the top has an upper groove; the air inlet end of the heating tube extends from the upper groove and is connected to an air inlet pipe, the air outlet end extends from the lower outlet and is connected to an air outlet pipe; the outer side of the top cover has an annular sealing ring, which is fixed to the top of the outer shell by fixing bolts and cooperates with the upper groove to form a sealed channel for the air inlet end of the heating tube; the bottom of the tank has a support platform, and the outer shell is installed on the support platform by bottom fixing bolts; the bottom cover and the bottom of the tank adopt a damping type closing structure.

[0010] Furthermore, the inner wall of the tank is uniformly distributed with cross-shaped layered bars.

[0011] Furthermore, the outer wall of the outer shell is symmetrically provided with ear seats for suspending and fixing the entire device.

[0012] Furthermore, two connecting rods are vertically fixed to the bottom of the bottom cover, and two L-shaped fixing rods are symmetrically arranged at the bottom of the support platform; the ends of the connecting rods and the ends of the fixing rods are aligned with each other to form diamond-shaped holes, and the diamond-shaped rods pass through all the diamond-shaped holes to achieve mechanical locking of the bottom cover.

[0013] Furthermore, the rhomboid rod and the rhomboid hole are fitted with an interference fit.

[0014] Furthermore, the wall thickness of the tank is less than 5mm, and high-temperature steam is introduced into the heating pipe to indirectly heat the material inside the tank.

[0015] Furthermore, the steam output pipe is equipped with a storage tank for condensing steam.

[0016] The beneficial effects of this utility model are:

[0017] (1) Improved purification efficiency: The combination of spiral heating tube and thin-walled tank provides hot steam to heat the internal materials and water to fully mix and dilute them, which greatly improves the purification efficiency; at the same time, the cross-shaped structure of the layered rod creates a three-dimensional turbulent flow field inside the tank, and the three-phase mixing of raw materials, water and steam improves the purification efficiency and solves the problem of insufficient heating in the central area of ​​the material.

[0018] (2) Improved ease of maintenance: The diamond-shaped rod locking mechanism enables quick disassembly of the bottom cover, and the assembly of this device is safe and convenient. Cleaning and replacement of each component is also very simple and easy.

[0019] (3) Energy consumption optimization: The pharmaceutical intermediates are purified by direct condensation of steam in the storage tank, which reduces heat loss. At the same time, the steam travels a longer distance in the spiral heating tube than in the direct-flow type, which increases the heat release time and greatly reduces the temperature difference of the tank, thus improving the purification efficiency. Attached Figure Description

[0020] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Figure 1 This is a three-dimensional schematic diagram of the device of this utility model;

[0022] Figure 2 This is an internal sectional view of the device of this utility model;

[0023] Figure 3 This is an exploded schematic diagram of the device of this utility model;

[0024] Figure 4 This is a schematic diagram of the tank structure of this utility model;

[0025] Figure 5 This is a schematic diagram of the outer shell structure of this utility model;

[0026] 1-Tank body, 11-Top cover, 111-Discharge port, 112-Exhaust pipe, 113-Steam output pipe, 12-Bottom cover, 121-Connecting rod, 122-Rhombus hole, 13-Layering rod, 2-Heating pipe, 21-Inlet pipe, 22-Outlet pipe, 3-Outer shell, 30-Cavity, 31-Lower outlet, 32-Upper groove, 33-Fixing bolt, 34-Ear seat, 4-Sealing ring, 5-Support platform, 51-L-shaped fixing rod, 6-Rhombus rod, 7-Gas storage tank. Detailed Implementation

[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0028] Example 1

[0029] See Figures 1 to 5 This utility model discloses a pharmaceutical intermediate purification and processing device. In the design process, the overall structure of the tank 1 must first be established. The core structure connection method is as follows: the top flange of the cylindrical tank 1 is connected to an openable top cover 11, and the bottom is connected to a bottom cover 12 through a hinge mechanism; the top cover 11 is welded with a discharge port 111 (diameter 200mm) in the center, and the side is welded with an exhaust pipe 112 at a 30° angle. The exhaust pipe 112 is rigidly connected to a steam output pipe 113 through a flange; the large diameter design of the discharge port 111 avoids material blockage, and the inclined layout of the exhaust pipe 112 prevents condensate backflow.

[0030] Meanwhile, the heating system of this device is constructed as follows: the spiral heating tube 2 is tightly wound around the outer wall of the tank 1 in a spiral manner, and the outer shell 3 is fastened to the outside of the heating tube 2 to form an annular sealed cavity 30; the air inlet end of the heating tube 2 passes through the upper groove 32 at the top of the outer shell 3 and is connected to the air inlet pipe 21, and the air outlet end passes through the lower outlet 31 at the bottom and is connected to the air outlet pipe 22; the key to the sealing of this device is that the rubber sealing ring 4 is embedded on the outside of the top cover 11 and is pressed to the top of the outer shell 3 by four sets of fixing bolts 33. The gap between the inner edge of the sealing ring 4 and the upper groove 32 is less than 0.5mm, forming a high-temperature steam sealing channel.

[0031] Furthermore, the wall thickness of tank 1 is limited to 4mm austenitic stainless steel, and 160℃ saturated steam is introduced into heating pipe 2, which raises the temperature of the liquid medicine in the tank to the boiling point within 5 minutes; the end flange of steam output pipe 113 is connected to gas storage tank 7 to realize the direct condensation and liquefaction of medicinal vapor.

[0032] It should be noted that the inner wall of tank 1 is laser-welded with a cross-shaped layered bar 13, with three groups in each layer distributed in a 120° rotation; the boiling liquid impacts the layered bar 13 to generate turbulent vortices, breaking the material adhesion, and the cross-shaped structure greatly improves the heat exchange efficiency in the central area.

[0033] Example 2

[0034] See Figures 1 to 5 This utility model discloses a pharmaceutical intermediate purification and processing device. The working process of this device is as follows:

[0035] Step 1: Feeding and heating

[0036] The powdered medicine is fed into the tank 1 through the feed port 111, and water is added to 80% of the volume; 160℃ steam is introduced into the spiral heating tube 2 through the air inlet pipe 21.

[0037] Step 2: Purification and Collection

[0038] The active ingredients are carried by the steam through the exhaust pipe 112 into the gas storage tank 7, and the active ingredients in the condensate are stored in the gas storage tank 7; the spiral heating tube 2 extends the steam travel to 4.2m, greatly improving the thermal energy utilization rate.

[0039] Step 3: Waste Residue Cleanup

[0040] After the machine stops, the interference fit is released by hammering the end of the diamond rod 6, and the bottom cover 12 falls automatically by gravity; the dregs fall directly into the conveyor belt and are transported out. At the same time, when cleaning the waste residue, the inner wall of the tank 1 can be rinsed with clean water from the discharge port 111 to clean the tank 1 and make it convenient for the next use.

[0041] The preferred embodiments of this utility model disclosed above are merely illustrative of the present utility model. These preferred embodiments do not exhaustively describe all details, nor do they limit the utility model to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of this utility model, thereby enabling those skilled in the art to better understand and utilize it. This utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A pharmaceutical intermediate purification and processing apparatus, characterized in that, The main components include a cylindrical tank (1); the tank (1) has an openable top cover (11) at the top and an openable bottom cover (12) at the bottom. The top cover (11) has a discharge port (111) and an exhaust pipe (112). The exhaust pipe (112) is connected to a steam output pipe (113) via a flange. A spiral heating tube (2) is fitted to the outer wall of the tank (1). The heating tube (2) is covered with an outer shell (3). A sealed cavity (30) is formed between the inner side of the outer shell (3) and the outer wall of the tank (1). The heating tube (2) is housed in the cavity (30). The bottom of the outer shell (3) has a lower outlet (31), and the top has an upper groove (32). The air inlet end of the heating tube (2) extends from the upper groove (32) and is connected to an air inlet pipe (21). The air outlet end extends from the lower outlet (31) and is connected to an air outlet pipe (22). An annular sealing ring (4) is provided on the outer side of the top cover (11). The ring (4) is fixed to the top of the outer shell (3) by fixing bolts (33) and cooperates with the upper groove (32) to form a sealed channel for the air inlet of the heating tube (2); the bottom of the tank (1) is provided with a support platform (5), and the outer shell (3) is installed on the support platform (5) by bottom fixing bolts (33); the bottom cover (12) and the bottom of the tank (1) adopt a damping cover structure; the inner wall of the tank (1) is evenly distributed with cross-shaped layered rods (13); the bottom of the bottom cover (12) is vertically fixed with two connecting rods (121), and the bottom of the support platform (5) is symmetrically provided with two L-shaped fixing rods (51); the end of the connecting rod (121) is aligned with the end of the fixing rod (51) to open a diamond hole (122), and the diamond rod (6) passes through all the diamond holes (122) to realize the mechanical locking of the bottom cover (12); the wall thickness of the tank (1) is less than 5mm, and high temperature steam is introduced into the heating tube (2) to indirectly heat the material in the tank.

2. The pharmaceutical intermediate purification and processing apparatus according to claim 1, characterized in that: The outer wall of the outer shell (3) is symmetrically provided with ear seats (34) for suspending and fixing the entire device.

3. The pharmaceutical intermediate purification and processing apparatus according to claim 1, characterized in that: The rhomboid rod (6) and the rhomboid hole (122) are fitted with an interference fit.

4. The pharmaceutical intermediate purification and processing apparatus according to claim 1, characterized in that: The steam output pipe (113) is equipped with a gas storage tank (7) for condensing steam.

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