Whitening anti-aging anti-virus supramolecular liposome emulsification dispersion machine

Abstract

The utility model discloses a kind of whitening anti-aging antiviral supramolecular liposome emulsification dispersion machines, it is related to dispersion machine technical field, including equipment frame and material bucket, inner container is arranged in material bucket, equipment frame includes base, lifting boom, speed reducer and first stirring shaft, speed reducer is fixedly installed on lifting boom, material bucket includes bucket body, discharging hand wheel and discharge valve, inner container includes isolation cylinder, speed reducer and second stirring shaft, first stirring shaft is fixedly installed on the output shaft of speed reducer, inner container is detachably installed in the upper end of material bucket, speed reducer is fixedly installed in the bottom of isolation cylinder, second stirring shaft is fixedly installed in the lower end of speed reducer, the upper end of speed reducer is provided with transmission shaft cooperated with first stirring shaft. The utility model has the advantages of double-speed stirring, stable structure, easy to clean, solves the problem of poor shear force control, uneven mixing and inconvenient operation of traditional equipment.

Description

Technical Field

[0001] This utility model relates to the field of dispersion technology, specifically a supramolecular liposome emulsification and dispersion machine for whitening, anti-aging, and antiviral purposes. Background Technology

[0002] With the rapid development of the biopharmaceutical and cosmetic industries, liposomes, as a nanocarrier with excellent biocompatibility and targeting properties, have been widely used in the delivery of active ingredients in areas such as whitening, anti-aging, and antiviral applications. Traditional liposome preparation methods mostly employ single emulsification or ultrasonic disruption processes. Commonly used emulsification and dispersion equipment typically only has a single stirring structure, which is insufficient to meet the varying requirements of liposome precursors for shear force and mixing uniformity at different stages.

[0003] Existing emulsification and dispersion equipment generally suffers from the following problems: on the one hand, the high shear force generated during high-speed stirring can easily damage the molecular structure of liposome precursors, affecting their encapsulation efficiency and stability; on the other hand, low-speed mixing has limited effect and uneven material distribution, resulting in low efficiency of subsequent film formation processes, uneven particle size distribution of products, and affecting the quality consistency of the final product. Therefore, a supramolecular liposome emulsification and dispersion machine for whitening, anti-aging, and antiviral purposes is needed to solve the above problems. Utility Model Content

[0004] The purpose of this invention is to provide a supramolecular liposome emulsification and dispersion machine for whitening, anti-aging, and antiviral purposes. It has the advantages of dual-speed stirring, stable structure, and easy cleaning, and solves the problems of poor shear force control, uneven mixing, and inconvenient operation of traditional equipment.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a supramolecular liposome emulsification and dispersion machine for whitening, anti-aging, and antiviral purposes, comprising a frame and a material tank, wherein the material tank is provided with an inner liner;

[0006] The equipment frame includes a base, a lifting arm, a reduction motor, and a first stirring shaft. The reduction motor is fixedly mounted on the lifting arm. The material hopper includes a hopper body, a discharge handwheel, a discharge valve plate, and a discharge valve. The inner liner includes an isolation cylinder, a reducer, and a second stirring shaft. The first stirring shaft is fixedly mounted on the output shaft of the reduction motor. The inner liner is detachably mounted on the upper end of the material hopper. The reducer is fixedly mounted on the bottom of the isolation cylinder. The second stirring shaft is fixedly mounted on the lower end of the reducer. The upper end of the reducer is provided with a transmission shaft that cooperates with the first stirring shaft. The bottom of the isolation cylinder is provided with a side discharge port that communicates with the material hopper. The discharge valve plate is movably mounted on the lower end of the discharge port.

[0007] As a preferred embodiment of the supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes of this utility model, a spiral blade is provided on the side end face of the first stirring shaft, and a dispersing blade is provided on the side end face of the second stirring shaft, wherein the dispersing blade has a rectangular structure.

[0008] As a preferred embodiment of the whitening, anti-aging, and antiviral supramolecular liposome emulsifying and dispersing machine of this utility model, the top edge of the barrel is provided with a positioning flange, and the edge of the isolation cylinder is provided with a handle that engages with the positioning flange.

[0009] As a preferred embodiment of the supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes of this utility model, the bottom of the first stirring shaft is provided with an internal hexagonal bushing that slides with the drive shaft, the drive shaft has a hexagonal prism structure, and the top of the drive shaft has a conical structure.

[0010] In a preferred embodiment of this invention, a supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes, the feeding valve plate is installed at the lower end of the feeding port and rotatably connected to the isolation cylinder. A first lead screw is provided on the side end face of the feeding handwheel, and a screw hole that mates with the first lead screw is provided on the side end face of the material barrel.

[0011] As a preferred embodiment of the supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes of this utility model, the lower end face of the feeding valve plate is provided with a vertical plate, and the front end of the first lead screw has a dome structure.

[0012] As a preferred embodiment of the supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes of this utility model, the base is provided with a clamping arm on its side end face, a second lead screw is provided on the clamping arm with a threaded connection, and a clamping plate is provided on the side end face of the second lead screw with a rotatable connection.

[0013] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0014] 1. This utility model solves the problem of liposome precursor damage caused by single shear force in traditional emulsification equipment by using a double-layer structure design of inner liner and material tank, combined with the linkage of low-speed and high-speed stirring shafts. The first stirring shaft in the inner liner achieves axial mixing and uniform distribution of materials in the upper and lower layers through the low-speed rotation of spiral blades, avoiding damage to the precursor structure by high shear force. After the mixed material enters the material tank through the discharge port, the second stirring shaft drives the dispersing blades to rotate at high speed, completing the crushing of large particles and liposome film formation. The staged processing not only protects the integrity of active ingredients, but also promotes the efficient formation of functional liposomes through high-speed centrifugation.

[0015] 2. This utility model solves the problems of inner tank misalignment, transmission instability, and material barrel shaking during equipment operation through the snap-fit ​​design of the positioning flange and handle, the cooperation between the hexagonal prism drive shaft and the internal hexagonal bushing, and the fixing structure of the second lead screw clamp. The positioning flange and handle prevent the inner tank from rotating and ensure precise alignment between the discharge port and the valve plate; the cooperation between the hexagonal prism drive shaft and the conical top ensures the stability of power transmission; the second lead screw squeezes the material barrel through the clamp to avoid vibration of the material barrel during high-speed dispersion. These designs improve the reliability of equipment operation and ensure the uniformity of liposome dispersion. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0017] Figure 2 This is a top view of the present invention;

[0018] Figure 3 For the present utility model Figure 2 Sectional view of AA in the middle;

[0019] Figure 4 This is a schematic diagram of the material bucket structure of this utility model;

[0020] Figure 5 For the present utility model Figure 3 Enlarged view at point B in the middle;

[0021] Figure 6 For the present utility model Figure 3 Enlarged view at point C;

[0022] Figure 7 This is a schematic diagram showing the engagement state of the transmission shaft, reducer, and second stirring shaft of this utility model.

[0023] In the diagram: 1. Equipment frame; 101. Base; 102. Lifting boom; 103. Clamping arm; 1031. Second lead screw; 1032. Clamping plate; 104. Gear motor; 105. First stirring shaft; 1051. Spiral blade; 1052. Hexagonal socket bushing; 2. Material bucket; 201. Bucket body; 2011. Positioning flange; 2012. Screw hole; 202. Discharge handwheel; 2021. First lead screw; 203. Discharge valve; 3. Inner liner; 301. Isolation cylinder; 3011. Discharge port; 3012. Handle; 302. Reducer; 303. Second stirring shaft; 3031. Dispersing blade; 304. Discharge valve plate; 3041. Vertical plate; 305. Drive shaft. Detailed Implementation

[0024] Please see Figures 1-7 A supramolecular liposome emulsification and dispersion machine for whitening, anti-aging and antiviral purposes includes a frame 1 and a material tank 2, with an inner liner 3 inside the material tank 2;

[0025] The equipment frame 1 includes a base 101, a lifting arm 102, a reduction motor 104, and a first stirring shaft 105. The reduction motor 104 is fixedly installed on the lifting arm 102. The material tank 2 includes a tank body 201, a discharge handwheel 202, and a discharge valve 203. The inner liner 3 includes an isolation cylinder 301, a reducer 302, and a second stirring shaft 303. The first stirring shaft 105 is fixedly installed on the output shaft of the reduction motor 104. The inner liner 3 is detachably installed on the upper end of the material tank 2. The reducer 302 is fixedly installed on the bottom of the isolation cylinder 301. The second stirring shaft 303 is fixedly installed on the lower end of the reducer 302. The upper end of the reducer 302 is provided with a transmission shaft 305 that cooperates with the first stirring shaft 105. The bottom of the isolation cylinder 301 is provided with a side discharge port 3011 that communicates with the material tank 2. The discharge valve plate 304 is movably installed on the lower end of the discharge port 3011.

[0026] The geared motor 104 drives the first stirring shaft 105 to rotate and stir the material in the inner liner 3 at low speed, so that the material is initially mixed and the high shear force is avoided to destroy the liposome precursor structure. Then, the material flows into the bottom of the material tank 2 through the discharge port. The first stirring shaft 105 drives the second stirring shaft 303 to rotate at high speed through the reducer 302, thereby centrifuging the material at high speed, breaking large particles and promoting liposome film formation. The second stirring shaft 303 is installed on the input shaft of the reducer 302, and the transmission shaft 305 is fixedly installed on the output shaft of the reducer 302 to improve the transmission ratio.

[0027] Furthermore, the side end face of the first stirring shaft 105 is provided with a spiral blade 1051, and the side end face of the second stirring shaft 303 is provided with a dispersing blade 3031, the dispersing blade 3031 having a rectangular structure.

[0028] The first stirring shaft 105 drives the spiral blades 1051 to rotate, promoting material mixing. The spiral blades 1051 can also drive the material to move axially, promoting the mixing of upper and lower layers of material and improving the mixing effect. Meanwhile, the rectangular dispersing blades 3031 have low resistance and can drive the material to disperse at high speed.

[0029] Furthermore, the top edge of the barrel 201 is provided with a positioning flange 2011, and the edge of the isolation cylinder 301 is provided with a handle 3012 that engages with the positioning flange 2011.

[0030] By using the handle 3012 and the positioning flange 2011, the isolation cylinder 301 is prevented from rotating on its own, and the isolation cylinder 301 and the material bucket 2 are positioned to ensure that the valve plate can be longitudinally aligned with the first lead screw 2021. The handle 3012 also makes it easy to lift the inner liner 3 and remove it for rinsing.

[0031] Furthermore, the bottom of the first stirring shaft 105 is provided with an internal hexagonal bushing 1052 that slides with the drive shaft 305. The drive shaft 305 has a hexagonal prism structure and a conical structure at the top.

[0032] The hexagonal prism-shaped drive shaft 305 is engaged with the internal hexagonal bushing 1052, which enables the first stirring shaft 105 to stably drive the drive shaft 305 to rotate. The top of the drive shaft 305 is designed as a tapered structure to facilitate the docking and engagement of the drive shaft 305 and the internal hexagonal bushing 1052.

[0033] Furthermore, the discharge valve plate 304 is installed at the lower end of the discharge port 3011 and is rotatably connected to the isolation cylinder 301. The side end face of the discharge handwheel 202 is provided with a first lead screw 2021, and the side end face of the material barrel 2 is provided with a screw hole 2012 that mates with the first lead screw 2021.

[0034] The feeding handwheel 202 drives the lead screw to rotate, thereby controlling the feed length of the lead screw. The first lead screw 2021 squeezes the feeding valve plate 304, thereby controlling the opening and closing of the feeding valve plate 304 and discharging the mixed material in the inner liner 3 into the material bucket 2 for dispersion.

[0035] Furthermore, a vertical plate 3041 is provided on the lower end face of the feeding valve plate 304, and the front end of the first lead screw 2021 is a dome structure.

[0036] By raising the lever arm through the vertical plate 3041, the first lead screw 2021 of the dome structure further reduces the frictional resistance between the lead screw and the vertical plate 3041, thereby improving the smoothness of adjustment.

[0037] Furthermore, a clamping arm 103 is provided on the side end face of the base 101, and a second lead screw 1031 with threaded connection is provided on the clamping arm 103. A clamping plate 1032 with rotatable connection is provided on the side end face of the second lead screw 1031.

[0038] By rotating the second lead screw 1031, the clamping plate 1032 is pressed against the material barrel 2, thereby fixing the material barrel 2 and preventing the material barrel 2 from shaking during the dispersion process.

[0039] In use, the inner liner 3 is attached to the upper end of the material hopper 2 via the handle 3012 and the positioning flange 2011 at the top of the material hopper 2. The second lead screw 1031 on the clamping arm 103 rotates, causing the clamping plate 1032 to squeeze the material hopper 2, thus fixing the material hopper 2 onto the equipment frame 1. The first stirring shaft 105 and the drive shaft 305 are then connected. Material is placed into the inner liner 3, and the reduction motor 104 is started, driving the first stirring shaft 105 to rotate. The spiral blades 1051 on the side end face of the first stirring shaft 105 rotate, promoting initial mixing and axial movement of the material, achieving mixing of the upper and lower layers. The mixed material is then further processed by rotating... The feeding handwheel 202 drives the first lead screw 2021 to rotate, and the first lead screw 2021 squeezes the feeding valve plate 304, so that the material flows into the bottom of the material barrel 2 through the side feeding port 3011. At this time, the inner hexagonal bushing 1052 at the bottom of the first stirring shaft 105 cooperates with the transmission shaft 305, driving the transmission shaft 305 of the reducer 302 to rotate, and then the second stirring shaft 303 is rotated at high speed through the reducer 302. The rectangular dispersion blades 3031 on the side end face of the second stirring shaft 303 drive the material to centrifuge at high speed, break large particles and promote liposome film formation, and complete the emulsification and dispersion of supramolecular liposomes for whitening, anti-aging and antiviral.

[0040] The above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A supramolecular liposome emulsification and dispersion machine for whitening, anti-aging, and antiviral purposes, comprising a frame (1) and a material tank (2), characterized in that: The material barrel (2) is provided with an inner liner (3); The equipment frame (1) includes a base (101), a lifting arm (102), a reduction motor (104), and a first stirring shaft (105). The reduction motor (104) is fixedly mounted on the lifting arm (102). The material bucket (2) includes a bucket body (201), a discharge handwheel (202), and a discharge valve (203). The inner liner (3) includes an isolation cylinder (301), a reducer (302), a discharge valve plate (304), and a second stirring shaft (303). The first stirring shaft (105) is fixedly mounted on the reduction motor (104). On the output shaft, the inner liner (3) is detachably installed on the upper end of the material barrel (2), the reducer (302) is fixedly installed on the bottom of the isolation cylinder (301), the second stirring shaft (303) is fixedly installed on the lower end of the reducer (302), the upper end of the reducer (302) is provided with a transmission shaft (305) that cooperates with the first stirring shaft (105), the bottom of the isolation cylinder (301) is provided with a side discharge port (3011) that communicates with the material barrel (2), and the discharge valve plate (304) is movably installed on the lower end of the discharge port (3011).

2. The supramolecular liposome emulsification and dispersion machine for whitening, anti-aging, and antiviral purposes as described in claim 1, characterized in that: The first stirring shaft (105) has a spiral blade (1051) on its side end face, and the second stirring shaft (303) has a dispersing blade (3031) on its side end face. The dispersing blade (3031) has a rectangular structure.

3. The supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes as described in claim 1, characterized in that: The top edge of the barrel (201) is provided with a positioning flange (2011), and the edge of the isolation cylinder (301) is provided with a handle (3012) that engages with the positioning flange (2011).

4. The supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes as described in claim 1, characterized in that: The bottom of the first stirring shaft (105) is provided with an internal hexagonal bushing (1052) that slides with the drive shaft (305). The drive shaft (305) has a hexagonal prism structure and the top of the drive shaft (305) has a conical structure.

5. The supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes as described in claim 1, characterized in that: The discharge valve plate (304) is installed at the lower end of the discharge port (3011) and is rotatably connected to the isolation cylinder (301). The side end face of the discharge handwheel (202) is provided with a first lead screw (2021), and the side end face of the material bucket (2) is provided with a screw hole (2012) that cooperates with the first lead screw (2021).

6. The supramolecular liposome emulsification and dispersion machine for whitening, anti-aging, and antiviral purposes as described in claim 5, characterized in that: The lower end face of the feeding valve plate (304) is provided with a vertical plate (3041), and the front end of the first lead screw (2021) is a dome structure.

7. The supramolecular liposome emulsifying and dispersing machine for whitening, anti-aging, and antiviral purposes as described in claim 1, characterized in that: The base (101) has a clamping arm (103) on its side end face, and a second lead screw (1031) with a threaded connection is provided on the clamping arm (103). The side end face of the second lead screw (1031) has a rotatably connected clamping plate (1032).

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