A syringe

Abstract

The application provides an injector, comprising an injector cavity, a push rod, a piston, an injection part and a cleaning branch pipe. The injection part is arranged at a first end of the injector cavity, a second end of the injector cavity is provided with a first opening, and the first end of the injector cavity is opposite to the second end of the injector cavity. The push rod is connected with the piston, and the push rod drives the piston to reciprocate in the injector cavity through the first opening. A side wall of the injector cavity is provided with a second opening, and the cleaning branch pipe communicates with the injector cavity through the second opening. When the injector is cleaned, the push rod drives the piston to move to a first space in a direction away from the injection part, so that the cleaning liquid flows into the injector cavity through the cleaning branch pipe and flows out from the injection part, and the first space is a space region between the first opening and the second opening. In this way, the cleaning liquid can flow in from the cleaning branch pipe and flow out from the injection part, without manually disassembling and cleaning the injector, and mechanical damage to the injector itself and the connecting components of the pipetting station is reduced.

Description

Technical Field

[0001] This application relates to the field of laboratory syringe cleaning, specifically to a syringe. Background Technology

[0002] In various laboratory experiments, automated pipetting stations play a crucial role in the precise transfer of liquids. Among these, the syringe, as a key component of the automated pipetting station, directly impacts the accuracy and efficiency of the experiments due to the ease and effectiveness of its cleaning.

[0003] Currently, the syringes used in automated pipetting stations are mainly cleaned manually. This cleaning method usually requires removing the syringe from the automated pipetting station and then cleaning it using specialized cleaning tools and reagents.

[0004] However, manually disassembling and cleaning syringes is cumbersome and time-consuming. For example, in high-throughput drug screening experiments, hundreds of pipetting operations may be required daily. Manually cleaning the syringes after each operation would significantly extend the experimental time. Moreover, manual cleaning cannot guarantee thorough cleaning, easily leaving liquids or impurities from the previous experiment inside the syringes, leading to cross-contamination. Furthermore, frequent disassembly and assembly of syringes can cause mechanical damage to the syringes themselves and the connecting components of the pipetting station, shortening the syringes' lifespan, increasing equipment replacement costs, and even causing the pipetting station to malfunction, affecting the stability of the entire experimental system. Utility Model Content

[0005] In view of the above problems, this application provides a syringe that overcomes or at least partially solves the problems of time-consuming manual cleaning of syringes, easy cross-contamination, and reduced syringe lifespan.

[0006] This application provides a syringe, including: a syringe cavity, a plunger, a piston, an injection section, and a cleaning branch tube. The injection section is located at a first end of the syringe cavity, and a first opening is provided at a second end of the syringe cavity, with the first end of the syringe cavity and the second end of the syringe cavity facing each other. The plunger is connected to the piston, and passes through the first opening to drive the piston to reciprocate within the syringe cavity. A second opening is provided on the side wall of the syringe cavity, and the cleaning branch tube communicates with the syringe cavity through the second opening. When cleaning the syringe, the plunger drives the piston to move away from the injection section into a first space, so that cleaning fluid flows into the syringe cavity through the cleaning branch tube and flows out from the injection section. The first space is the space region between the first opening and the second opening.

[0007] This application provides a syringe with a second opening on the side wall of the syringe cavity, through which a cleaning branch tube communicates with the syringe cavity. When the syringe needs cleaning, the push rod drives the piston to move away from the injection section into a first space. This prevents the piston from blocking the second opening, thus preventing the cleaning fluid from entering the syringe cavity, or prevents the cleaning fluid from entering the syringe cavity and being blocked by the piston from flowing out of the injection section. Thus, the syringe provided by this application allows the cleaning fluid to flow in through the cleaning branch tube and out through the injection section, eliminating the need for manual disassembly and cleaning of the syringe, reducing experimental time, and minimizing mechanical damage to the syringe itself and the connecting components of the pipetting station. Moreover, the cleaning fluid can flow freely from the cleaning branch tube into the injection section, resulting in more thorough cleaning compared to manual cleaning and preventing cross-contamination.

[0008] In one alternative approach, the angle between the cleaning branch tube and the portion of the syringe cavity near the injection site is an obtuse angle.

[0009] In this way, the gravity of the cleaning fluid can be used to make it easier for the cleaning fluid to flow out from the injection section, and it is also convenient to clean the piston when the piston is near the second opening.

[0010] In one alternative embodiment, the syringe further includes a seal for sealing the first opening. The seal has a through-hole, and after the seal seals the first opening, the plunger passes through the through-hole to drive the piston to reciprocate within the syringe cavity.

[0011] In one alternative embodiment, the syringe further includes a sealing ring, wherein the end of the seal facing the syringe cavity has a groove, and the sealing ring is disposed within the groove.

[0012] Thus, through the double sealing of the sealing ring and the sealing element, the syringe provided in this application embodiment can achieve good sealing performance.

[0013] In one alternative approach, multiple cleaning branches can be used to speed up the cleaning process.

[0014] In one alternative approach, when there are two cleaning branch pipes, the two cleaning branch pipes are arranged opposite each other to make the cleaning more thorough.

[0015] In one alternative configuration, the push rod has external threads, the piston has internal threads, and the push rod and piston are connected by threads.

[0016] In one alternative embodiment, the end of the push rod away from the piston is provided with a clamping part, so that the telescopic module clamps the clamping part and drives the push rod to reciprocate.

[0017] In one alternative approach, the cleaning branch pipe is provided with a pipe interface, and the cleaning branch pipe is connected to the outlet of the cleaning fluid through the pipe interface.

[0018] The above description is merely an overview of the technical solutions of the embodiments of this application. In order to better understand the technical means of the embodiments of this application and to implement them in accordance with the contents of the specification, and to make the above and other objects, features and advantages of the embodiments of this application more obvious and understandable, specific implementation methods of this application are described below. Attached Figure Description

[0019] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 This is a schematic diagram of the structure of a syringe provided for some embodiments of this application.

[0021] Figure 2 This is a schematic diagram of the structure of a seal provided in some embodiments of this application.

[0022] Figure 3 This is a schematic diagram of the structure of the seal and sealing ring provided in some embodiments of this application.

[0023] Figure 4 Schematic diagram of syringe installation provided for some embodiments of this application Figure 1 .

[0024] Figure 5 Schematic diagram of syringe installation provided for some embodiments of this application Figure 2 .

[0025] Figure 6 This is a schematic diagram illustrating the cleaning of a syringe according to some embodiments of this application.

[0026] Figure 7 This is a schematic diagram illustrating another syringe cleaning process provided in some embodiments of this application. Detailed Implementation

[0027] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0028] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used herein in the specification of the application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

[0029] The terms "comprising" and "having," and any variations thereof, used in the specification, claims, and drawings of this application are intended to cover without excluding other meanings. The words "a" or "an" do not exclude the presence of multiples.

[0030] The term "embodiment" as used herein means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of the phrase "embodiment" in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a separate or alternative embodiment mutually exclusive with other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0031] Furthermore, the terms "first," "second," etc., in the specification and claims of this application or in the aforementioned drawings are used to distinguish different objects rather than to describe a specific order, and may explicitly or implicitly include one or more of the features.

[0032] In the description of this application, unless otherwise stated, "multiple" means two or more (including two), and similarly, "multiple groups" means two or more (including two groups).

[0033] In the description of this application, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linkage" should be interpreted broadly. For example, "connection" or "linkage" in mechanical structures can refer to a physical connection, such as a fixed connection, for example, a connection fixed by fasteners, such as a connection fixed by screws, bolts, or other fasteners; a physical connection can also be a detachable connection, such as a snap-fit ​​or interlocking connection; a physical connection can also be an integral connection, such as a connection formed by welding, bonding, or integral molding. In circuit structures, "connection" or "linkage" can refer not only to a physical connection but also to an electrical connection or a signal connection. For example, it can be a direct connection, i.e., a physical connection, or an indirect connection through at least one intermediate component, as long as the circuit is connected; it can also refer to the internal connection of two components. Signal connection can refer not only to signal connection through a circuit but also to signal connection through a media, such as radio waves. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0034] Figure 1This is a schematic diagram of the structure of a syringe provided in some embodiments of this application, with reference to... Figure 1 The present application provides a syringe comprising: a syringe cavity 01, a plunger 02, a piston 03, an injection section 04, and a cleaning branch tube 05.

[0035] In some embodiments, there can be multiple cleaning branch pipes 05. For example, when there are two cleaning branch pipes, the two cleaning branch pipes can be arranged relative to each other.

[0036] The injection part 04 is located at the first end of the syringe cavity 01, and the second end of the syringe cavity 01 is provided with a first opening. The first end of the syringe cavity 01 is opposite to the second end of the syringe cavity 01.

[0037] The push rod 02 is connected to the piston 03. The push rod 02 passes through the first opening and drives the piston 03 to reciprocate within the syringe cavity 01. Specifically, the end of the push rod 02 near the piston 03 has an external thread, and the piston 03 has an internal thread. The push rod 02 and the piston 03 are connected by threads. The syringe cavity 01 is made of a transparent material, such as glass, to facilitate observation of the liquid flow inside the syringe cavity 01 and the movement of the piston 03.

[0038] The syringe cavity 01 has a second opening on its side wall, and the cleaning branch tube 05 communicates with the syringe cavity 01 through the second opening. The second opening is located in the side wall of the syringe cavity 01 near the first opening.

[0039] When cleaning the syringe, the push rod 02 drives the piston 03 to move away from the injection part 04 into the first space, so that the cleaning fluid flows into the syringe cavity 01 through the cleaning branch tube 05 and flows out from the injection part 04. The first space is the space area between the first opening and the second opening.

[0040] It should be noted that in practical applications, the automatic pipetting station includes a telescopic module, which is used to drive the push rod 02 to reciprocate in the direction of approaching or moving away from the injection section 04.

[0041] In some embodiments, the end of the push rod 02 away from the piston 03 is provided with a clamping part 06 so that the telescopic module can clamp the clamping part 06 and drive the push rod 02 to reciprocate.

[0042] This application provides a syringe with a second opening on the side wall of the syringe cavity 01. A cleaning branch tube 05 communicates with the syringe cavity 01 through the second opening. When the syringe needs cleaning, the push rod 02 drives the piston 03 to move away from the injection part 04 into the first space. This prevents the piston 03 from blocking the second opening, thus preventing the cleaning fluid from entering the syringe cavity 01, or prevents the cleaning fluid from entering the syringe cavity 01 and being blocked by the piston 03 from flowing out of the injection part 04. Thus, the syringe provided by this application allows the cleaning fluid to flow in through the cleaning branch tube 05 and out through the injection part 04, eliminating the need for manual disassembly and cleaning of the syringe, reducing experimental time, and minimizing mechanical damage to the syringe itself and the connecting components of the pipetting station. Moreover, the cleaning fluid can flow in through the cleaning branch tube 05 and out through the injection part 04, resulting in more thorough cleaning compared to manual cleaning and preventing cross-contamination.

[0043] In some embodiments, the angle α between the cleaning branch tube 05 and the portion of the syringe cavity 01 near the injection section 04 is an obtuse angle.

[0044] In this way, the gravity of the cleaning fluid can be used to make it easier for the cleaning fluid to flow out from the injection part 04. Moreover, when the piston 03 is located near the second opening and does not block the second opening, it is also convenient to clean the piston 03.

[0045] Figure 2 This is a schematic diagram of the structure of the seal provided in some embodiments of this application. Figure 3 This is a schematic diagram of the structure of the seal and sealing ring provided in some embodiments of this application, with reference to... Figure 2 and Figure 3 In some embodiments, the syringe may further include a seal 07 for sealing the first opening. The seal 07 may be made of borosilicate glass or polytetrafluoroethylene (PTFE) plastic.

[0046] The seal 07 has a through hole. After the seal 07 seals the first opening, the push rod 02 passes through the through hole and drives the piston 03 to reciprocate within the syringe cavity 01.

[0047] In some embodiments, the syringe may further include a sealing ring 08, wherein a groove 071 is provided at one end of the seal 07 facing the syringe cavity 01, and the sealing ring 08 is disposed within the groove 071. The sealing ring 08 may be made of an elastic material such as rubber or silicone, and has good elasticity and sealing performance to prevent leakage of cleaning fluid or experimental liquid.

[0048] Thus, through the double sealing of the sealing ring 08 and the sealing element 07, the syringe provided in this application embodiment can achieve better sealing performance.

[0049] In some embodiments, the cleaning branch pipe 05 is provided with a pipe interface 051. For example, the pipe interface 051 can be a flexible hose, and the cleaning branch pipe 05 can be connected to the outlet of the cleaning fluid through the pipe interface 051.

[0050] Figure 4 Schematic diagram of syringe installation provided for some embodiments of this application Figure 1 , Figure 5 Schematic diagram of syringe installation provided for some embodiments of this application Figure 2 The following is combined with Figures 4-5 The installation and operation process of a syringe provided in some embodiments of this application are described.

[0051] In practical applications, some embodiments of this application provide a syringe that, during installation, refers to... Figure 3 First, the sealing ring 08 can be placed in the groove 071 of the sealing element 07, for reference. Figure 4 Then, push rod 02 is passed through the through hole of seal 07, as shown in the reference. Figure 5 Then, the plunger 02 and piston 03 are connected by threads. Then, the plunger 02, piston 03 and seal 07 are put into the syringe cavity 01. The seal 07 and sealing ring 08 are used to seal the first opening. In this way, the installed syringe can be used for normal cleaning, liquid aspiration and liquid dispensing operations.

[0052] In practical work, the automatic pipetting station also includes a controller and a cleaning fluid supply module. The cleaning fluid outlet is located in the cleaning fluid supply module. Both the telescopic module and the cleaning fluid supply module can be connected to the controller. The controller can preset the telescopic range of the telescopic module during cleaning, suction and dispensing, as well as the total amount of cleaning fluid and the time provided by the cleaning fluid supply module.

[0053] Figure 6 This is a schematic diagram illustrating the cleaning process of a syringe according to some embodiments of this application. Figure 7 This is a schematic diagram illustrating another syringe cleaning process provided in some embodiments of this application. Figure 6 and Figure 7 This diagram illustrates the cleaning operation when piston 03 is in different positions within the first space. (Reference) Figure 6 and Figure 7When cleaning the syringe, the telescopic module can drive the push rod 02 to move away from the piston 03 according to the preset telescopic range. Then, the push rod 02 can drive the piston 03 to move away from the injection part 04 into the first space. The cleaning fluid can flow into the syringe cavity 01 through the cleaning branch tube 05 and flow out from the injection part 04. After the preset total amount of cleaning fluid and time are reached, the telescopic module can drive the push rod 02 to move closer to the piston 03 according to the preset telescopic range until the piston 03 contacts the injection part 04 to empty the cleaning fluid. In this way, the cleaning operation is completed without the need for manual disassembly and cleaning of the syringe.

[0054] When the syringe draws liquid, the telescopic module can move the push rod 02 towards the piston 03 according to the preset telescopic range until the piston 03 contacts the injection part 04. At this time, the second opening is above the piston 03, and the piston 03, syringe cavity 01, and injection part 04 form a sealed space. When the injection part 04 is aligned with the experimental liquid to be drawn, the telescopic module continues to move the push rod 02 away from the piston 03 according to the preset telescopic range. Under negative pressure, the experimental liquid is drawn into the syringe cavity 01. When the syringe is moved to the desired discharge position, the telescopic module can again move the push rod 02 towards the piston 03 according to the preset telescopic range to discharge the experimental liquid from the syringe, completing the discharge operation. It is worth noting that during both the aspiration and discharge processes, the piston 03 is outside the first space to facilitate precise aspiration and discharge.

[0055] Those skilled in the art will understand that although some embodiments herein include certain features included in other embodiments, combinations of features from different embodiments are intended to be within the scope of this application and form different embodiments. For example, in the claims, any of the claimed embodiments can be used in any combination.

[0056] The above-described embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this application.

Claims

1. A syringe, characterized in that, The syringe includes: a syringe cavity, a plunger, a piston, an injection section, and a cleaning branch tube; The injection section is located at the first end of the syringe cavity, and the second end of the syringe cavity is provided with a first opening. The first end of the syringe cavity and the second end of the syringe cavity are opposite to each other. The push rod is connected to the piston, and the push rod passes through the first opening to drive the piston to reciprocate within the syringe cavity; The side wall of the syringe cavity is provided with a second opening, and the cleaning branch tube communicates with the syringe cavity through the second opening; When cleaning the syringe, the push rod drives the piston to move away from the injection part into the first space, so that the cleaning fluid flows into the syringe cavity through the cleaning branch and flows out from the injection part, wherein the first space is the space area between the first opening and the second opening.

2. The syringe according to claim 1, characterized in that, The angle between the cleaning branch tube and the portion of the syringe cavity near the injection section is an obtuse angle.

3. The syringe according to claim 1, characterized in that, The syringe also includes a seal for sealing the first opening; The sealing element has a through hole. After the sealing element seals the first opening, the push rod passes through the through hole and drives the piston to reciprocate within the syringe cavity.

4. The syringe according to claim 3, characterized in that, The syringe also includes a sealing ring, and the sealing element has a groove at one end facing the syringe cavity, with the sealing ring disposed in the groove.

5. The syringe according to claim 1, characterized in that, There are multiple cleaning branch pipes.

6. The syringe according to claim 1, characterized in that, When there are two cleaning branch pipes, the two cleaning branch pipes are arranged opposite to each other.

7. The syringe according to claim 1, characterized in that, The push rod has an external thread, the piston has an internal thread, and the push rod and the piston are connected by a thread.

8. The syringe according to claim 1, characterized in that, The push rod is provided with a clamping part at the end away from the piston, so that the telescopic module can clamp the clamping part and drive the push rod to reciprocate.

9. The syringe according to claim 1, characterized in that, The cleaning branch pipe is provided with a pipe interface, and the cleaning branch pipe is connected to the outlet of the cleaning fluid through the pipe interface.

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