An immunofluorescence test strip analysis device
By incorporating a fixing frame, locking blocks, and guide rods within the card compartment, the problem of unstable insertion and clamping of test strips when their specifications change is solved, ensuring stable fixation of the test strips during the testing process and guaranteeing the accuracy of the test results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHANGHAI MANMAN BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-05-21
- Publication Date
- 2026-06-26
Smart Images
Figure CN224416879U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of analyzer technology, and in particular to an immunofluorescence test strip analysis device. Background Technology
[0002] According to a miniature fluorescence immunoassay analyzer and its image processing method disclosed in Chinese Publication No. CN114486841B, the method includes: acquiring at least two frames of fluorescence images, filtering them respectively to obtain a first fluorescence image and a second fluorescence image; obtaining a first threshold based on the fluorescence intensity curve; comparing the pixel values of corresponding pixels in the first and second fluorescence images, and obtaining a third fluorescence image based on the first threshold; processing the third fluorescence image using the maximum inter-class variance method to obtain a second threshold, and performing binarization segmentation on the third fluorescence image based on the second threshold to obtain a binarized image; iteratively scanning all pixels in the binarized image, marking similar pixels and recording them in a labeling matrix to obtain a target region; calculating the average gray value of the target region, and obtaining the concentration of antigen or antibody in the sample based on the proportional relationship between the gray value and the fluorescence signal intensity. This invention reduces detection errors and ensures the accuracy of detection results.
[0003] The aforementioned and existing dry fluorescence analyzers typically employ a fixed slot design, which can only accommodate test strips of a specific width and thickness. If the specifications of the test strip change, it cannot be placed into the slot, or the strip may not be securely clamped, leading to displacement during the test and affecting the accuracy of the test results. Utility Model Content
[0004] The purpose of this invention is to address the shortcomings of existing technologies, such as the inability to insert test strips into the card compartment when the specifications of the test strips are changed, and the displacement of the test strips during the testing process due to insecure clamping. Therefore, an immunofluorescence test strip analysis device is proposed.
[0005] To achieve the above objectives, the present invention adopts the following technical solution: an immunofluorescence test strip analysis device, comprising an analyzer, a slot on the surface of the analyzer, a card compartment inside the slot, two first fixing brackets on the top surface of the card compartment, second fixing brackets on both sides of the card compartment, a test strip body inside the card compartment, two first locking blocks on the top of the test strip body, second locking blocks on both sides of the test strip body, two guide rods on the surface of each of the two first locking blocks and the two second locking blocks, a return spring on the outside of each of the eight guide rods, a moving block on the top surface of each of the two second fixing brackets, a screw on one side of the card compartment, a guide rod on the side of the card compartment away from the screw, a fluorescence detector on the top of the card compartment, a processor on the side of the fluorescence detector away from the card compartment, a battery at the bottom of the processor, a partition between the battery and the card compartment, a guide rod on the surface of the partition near the card compartment, and a brushless motor on the side of the screw away from the moving block.
[0006] Preferably, the card compartment, fluorescence detector, processor, battery, separator, brushless motor, guide rod, and screw are all located inside the analyzer. The card compartment is installed inside the card slot. The fluorescence detector and processor are bolted to the analyzer, and the battery is snapped into the analyzer. The separator is integrally formed with the analyzer.
[0007] Preferably, the two first fixing frames, the two second fixing frames, and the two moving blocks are all integrally formed with the card compartment, the test strip body is installed inside the card compartment, the two second fixing frames and the two moving blocks are mirror images of the card compartment, and the positions of the two first fixing frames correspond one-to-one.
[0008] Preferably, the two first card blocks and the two second card blocks are all located inside the card compartment, and the positions of the two first card blocks correspond one-to-one with the positions of the two first fixing frames, and the positions of the two second card blocks correspond one-to-one with the positions of the two second fixing frames.
[0009] Preferably, both first locking blocks and both second locking blocks are integrally formed with the two guide rods on the surface, and the return springs are all sleeved with the guide rods.
[0010] Preferably, the two guide rods on the surfaces of the two first card blocks both penetrate the first fixing frame, and the two guide rods on the surfaces of the two second card blocks both penetrate the second fixing frame.
[0011] Preferably, the guide rod and the two brushless motors are all bolted to the partition plate, and the positions of the guide rod and the brushless motors correspond one-to-one with the positions of the two moving blocks. The screw is axially connected to the brushless motor, and one end of the screw and the guide rod both pass through the moving blocks.
[0012] Beneficial effects
[0013] In this invention, when the test strip is placed into the card compartment, the test strip body simultaneously presses against the first and second locking blocks in the card compartment, causing the first and second locking blocks to move along the direction of the guide rod. When the test strip body is fully installed in the card compartment, the first locking block moves downward through a return spring and presses against the test strip body to prevent it from moving up and down. Both second locking blocks are pressed towards the center of the card compartment through return springs to prevent the test strip body from moving left and right. This completes the all-round fixation of the test strip body, solving the shortcomings of being unable to be placed into the card compartment when the test strip specifications change and the test strip displacement during the testing process due to insecure clamping. Attached Figure Description
[0014] Figure 1 This is an isometric drawing of the present invention;
[0015] Figure 2 This is a front view of the present invention;
[0016] Figure 3 For the present utility model Figure 2 Sectional view at point AA;
[0017] Figure 4 For the present utility model Figure 2 Sectional view at BB;
[0018] Figure 5 This is a partial perspective view of the present invention;
[0019] Figure 6 This is a partial top view of the present invention;
[0020] Figure 7 For the present utility model Figure 6 Sectional view at CC.
[0021] Legend:
[0022] 1. Analyzer; 2. Card slot; 3. Card compartment; 4. Fluorescence detector; 5. Processor; 6. Battery; 7. Separator; 8. Brushless motor; 9. Screw; 10. Guide rod; 11. Test strip body; 12. First fixing frame; 13. Second fixing frame; 14. First locking block; 15. Second locking block; 16. Guide rod; 17. Return spring; 18. Moving block. Detailed Implementation
[0023] To make the technical means, creative features, and achieved objectives and effects of this utility model easier to understand, the present utility model is further described below with reference to specific embodiments and accompanying drawings. However, the following embodiments are merely preferred embodiments of this utility model and not all of them. Other embodiments obtained by those skilled in the art based on the embodiments described in the implementation plan without creative effort are all within the protection scope of this utility model.
[0024] The specific embodiments of this utility model are described below with reference to the accompanying drawings. Specific Implementation Example 1:
[0026] Reference Figure 1-7An immunofluorescence test strip analysis device includes an analyzer 1. The analyzer 1 has a slot 2 on its surface, and a card compartment 3 inside the slot 2. Two first fixing brackets 12 are located on the top surface of the card compartment 3, and second fixing brackets 13 are located on both sides of the card compartment 3. A test strip body 11 is located inside the card compartment 3. Two first locking blocks 14 are located on the top of the test strip body 11, and second locking blocks 15 are located on both sides of the test strip body 11. Two guide rods 16 are located on the surfaces of the two first locking blocks 14 and the two second locking blocks 15. Return springs 17 are located on the exterior of the eight guide rods 16. Moving blocks 18 are located on the top surfaces of the two second fixing brackets 13. A screw 9 is provided on one side of the card compartment 3. A guide rod 10 is provided on the side of the card compartment 3 away from the screw 9. A fluorescence detector 4 is provided on the top of the card compartment 3. A processor 5 is provided on the side of the fluorescence detector 4 away from the card compartment 3. A battery 6 is provided at the bottom of the processor 5. A partition 7 is provided between the battery 6 and the card compartment 3. A guide rod 10 is provided on the surface of the partition 7 near the card compartment 3. A brushless motor 8 is provided on the side of the screw 9 away from the moving block 18. The card compartment 3, fluorescence detector 4, processor 5, battery 6, partition 7, brushless motor 8, guide rod 16, and screw 9 are all located inside the analyzer 1. The card compartment 3 is installed inside the card slot 2. The fluorescence detector 4 and processor 5 are all located inside the card slot 2. The analyzer 1 is bolted to the analyzer 1, and the battery 6 is snapped into the analyzer 1. The partition 7 is integrally formed with the analyzer 1. The two first fixing frames 12, the two second fixing frames 13, and the two moving blocks 18 are all integrally formed with the card compartment 3. The test strip body 11 is installed inside the card compartment 3. The two second fixing frames 13 and the two moving blocks 18 are mirror images of the card compartment 3, and the positions of the two first fixing frames 12 correspond one-to-one. The two first locking blocks 14 and the two second locking blocks 15 are all located inside the card compartment 3. The positions of the two first locking blocks 14 correspond one-to-one with the positions of the two first fixing frames 12, and the positions of the two second locking blocks 15 correspond one-to-one with the positions of the two second fixing frames 12. The positions of the frame 13 are one-to-one. The two first locking blocks 14 and the two second locking blocks 15 are integrally formed with the two guide rods 16 on the surface, and the return springs 17 are sleeved with the guide rods 16. The two guide rods 16 on the surface of the two first locking blocks 14 pass through the first fixed frame 12, and the two guide rods 16 on the surface of the two second locking blocks 15 pass through the second fixed frame 13. The guide rod 10 and the two brushless motors 8 are bolted to the partition plate 7, and the positions of the guide rod 10 and the brushless motors 8 are one-to-one with the positions of the two moving blocks 18. The screw 9 is shaft-connected to the brushless motor 8, and one end of the screw 9 and the guide rod 10 both pass through the moving block 18.
[0027] Analyzer 1, serving as the carrier and control center of the entire device, provides installation space for internal components and protects the internal structure from external interference. Existing analyzers 1 typically feature an operating interface, allowing users to input commands, initiate the detection process, and set relevant parameters. It also has a display function, providing a clear view of the test results for easy reading. The slot 2 provides a precise insertion path for the test strip body 11, guiding it accurately into the card compartment 3, ensuring that the test strip body 11 can be accurately grasped and secured by subsequent components. The card compartment 3 is the key component for housing the test strip body 11. The top and side surfaces of the card compartment 3 are respectively equipped with a first fixing frame 12 and a second fixing frame 13, which provide the mounting and support foundation for the first locking block 14, the second locking block 15, and their associated guide rods 16 and return springs 17. Simultaneously, the card compartment 3 is integrally formed with the moving block 18. Driven by the moving block 18, the entire card compartment 3 can be moved, thereby transporting the test strip body 11 within the card compartment 3 to the area below the fluorescence detector 4 for detection. The fluorescence detector 4, based on fluorescence detection technology, emits excitation light of a specific wavelength. When the excitation light shines on the test strip body 11, if there are fluorescently labeled substances on the test strip, these substances will absorb the energy of the excitation light and emit fluorescence. The fluorescence detector 4 can capture these fluorescence signals and convert them into electrical signals, which are then transmitted to the processor 5 for processing. The processor 5 acts as the "brain" of the device, responsible for receiving the electrical signals from the fluorescence detector 4. After receiving the signals, the processor 5 analyzes, calculates, and processes the electrical signals according to preset algorithms and programs. On the one hand, it can determine the concentration of the detected substance, the presence of specific pathogens, etc.; on the other hand, the processor 5 also bears the important responsibility of controlling the coordinated operation of various components of the instrument. The battery 6 provides a continuous and stable power supply for the entire device. Through internal chemical reactions, the battery 6 converts chemical energy into electrical energy, providing the energy required for the operation of all electrical components inside the analyzer 1, such as the fluorescence detector 4, the processor 5, and the brushless motor 8, ensuring that the instrument can work normally without an external power source. The partition 7 mainly serves as isolation and support. A guide rod 10 is installed on the surface of the partition 7 near the cartridge 3, providing a mounting point for the guide rod 10 and ensuring its stability within the device. The brushless motor 8 operates using the principle of electromagnetic induction, converting electrical energy into mechanical energy. Upon receiving a command from the processor 5, the brushless motor 8 begins to operate, its motor shaft driving the screw 9, which is shaft-connected to it, to rotate, thus providing power for the subsequent movement of the cartridge 3. The screw 9 is shaft-connected to the brushless motor 8 and rotates under its drive. The outer surface of the screw 9 has threads that engage with the internal threads of the moving block 18. When the screw 9 rotates, according to the principle of threaded transmission, the moving block 18 moves linearly along the axial direction of the screw 9, thereby moving the cartridge 3, which is integrally formed with the moving block 18.One end of the guide rod 10 is fixed to the partition 7, and its function is to guide the movement of the moving block 18 and the card compartment 3. During the movement of the moving block 18 along the screw 9, the guide rod 10 restricts the moving block 18 to move only in a specific straight direction, preventing it from deviating, shaking, or rotating during movement, ensuring that the card compartment 3 can move smoothly and accurately to the bottom of the fluorescence detector 4 for detection. The first fixing frame 12 is fixed to the top surface of the card compartment 3, providing installation and guiding support for the first card block 14 and its matching guide rod 16. The guide rod 16 on the first card block 14 passes through the first fixing frame 12, allowing the first card block 14 to move only up and down along the axial direction of the guide rod 16, ensuring that the movement trajectory of the first card block 14 is accurate and stable when fixing and releasing the test strip body 11. The second fixing frame 13 is installed on both sides of the card compartment 3, and its function is similar to that of the first fixing frame 12, providing installation and guiding support for the second card block 15 and its matching guide rod 16. The guide rod 16 on the second locking block 15 passes through the second fixing frame 13, allowing the second locking block 15 to move only left and right along the axial direction of the guide rod 16. This ensures that the second locking block 15 can accurately fix the test strip body 11 laterally during fixing and releasing operations. When the test strip body 11 is inserted into the card compartment 3, the top of the test strip body 11 presses against the first locking block 14, causing it to move upward along the guide rod 16, while simultaneously compressing the return spring 17. After the test strip is fully inserted, the return spring 17 returns to its original shape, pushing the first locking block 14 downward, thereby tightly pressing the top of the test strip body 11, restricting the vertical movement of the test strip, ensuring that the test strip does not shift vertically during testing, and guaranteeing the accuracy of the test results. When the test strip body 11 is inserted into the card compartment 3, the two sides of the test strip body 11 press against the second locking block 15, causing it to move to both sides along the guide rod 16, similarly compressing the return spring 17. Once the test strip is fully inserted, the return spring 17 returns to its original shape, pushing the second locking block 15 towards the center of the cartridge 3. This tightly presses the sides of the test strip body 11, restricting its horizontal movement and preventing it from wobbling during testing, thus ensuring testing stability. The guide rod 16 is integrally formed with the first locking block 14 and the second locking block 15, respectively, and passes through the corresponding first fixing frame 12 and second fixing frame 13. The guide rod 16 provides precise guidance for the movement of the first locking block 14 and the second locking block 15, ensuring that the blocks move smoothly in a straight line when pressed by the test strip and pushed by the return spring 17, thereby accurately fixing and releasing the test strip body 11. Specific Implementation Example 2:
[0029] Reference Figure 1-7An immunofluorescence test strip analysis device, further based on the basic structure in Specific Embodiment 1, allows the user to insert the test strip body 11 into the card compartment 3 via the slot 2 when preparing for testing. During insertion, the top of the test strip body 11 presses against the first locking block 14, causing it to move upward along the guide rod 16, while the sides press against the second locking blocks 15, causing them to move laterally along the guide rod 16. During this process, the return spring 17 is compressed. After the test strip body 11 is fully inserted into the card compartment 3, the return spring 17 returns to its original state, pushing the first locking block 14 downward to press the top of the test strip body 11, and the second locking block 15 presses against the sides of the test strip body 11 towards the center of the card compartment 3, thus fixing the test strip body 11 in all directions from top to bottom and left to right, ensuring the positional stability of the test strip during the testing process.
[0030] Next, the user issues a detection command through the operating interface of the analyzer 1. Upon receiving the command, the processor 5 starts the brushless motor 8. The brushless motor 8 drives the screw 9 to rotate. Because the moving block 18 is threadedly engaged with the screw 9 and guided and restricted by the guide rod 10, the moving block 18 will move linearly along the axis of the screw 9, thereby driving the cartridge 3, which is integrally formed with the moving block 18, to move. The cartridge 3 stops after moving to the bottom of the fluorescence detector 4.
[0031] At this point, the processor 5 controls the fluorescence detector 4 to start, and the fluorescence detector 4 emits excitation light of a specific wavelength to illuminate the test strip body 11 in the card compartment 3. If there is a fluorescent marker on the test strip that binds to the target analyte in the sample, it will emit fluorescence under the excitation light. The fluorescence detector 4 captures the fluorescence signal and converts it into an electrical signal, which is then transmitted to the processor 5. The processor 5 analyzes, calculates, and processes the electrical signal, converting it into a specific detection result according to a preset algorithm. Finally, the result is presented to the user through the display interface of the analyzer 1, thus completing the entire detection process of the immunofluorescence test strip.
[0032] In summary:
[0033] 1. When the test strip body 11 is placed into the card compartment 3, the test strip body 11 will simultaneously squeeze the first card block 14 and the second card block 15 in the card compartment 3, causing the first card block 14 and the second card block 15 to move along the direction of the guide rod 16 respectively. When the test strip body 11 is fully installed into the card compartment 3, the first card block 14 moves downward through the return spring 17 and squeezes the test strip body 11 to prevent the test strip body 11 from moving up and down. Both second card blocks 15 are squeezed towards the center of the card compartment 3 through the return spring 17 to prevent the test strip body 11 from moving left and right. This completes the all-round fixation of the test strip body 11, solving the shortcomings of the test strip being unable to be placed into the card compartment 3 when the specifications are changed and the test strip displacement caused by the insecure clamping during the testing process.
[0034] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.
[0035] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.
Claims
1. An immunofluorescence test strip analysis device, comprising an analyzer (1), characterized in that: The analyzer (1) has a slot (2) on its surface, and a card compartment (3) is provided inside the slot (2). The top surface of the card compartment (3) is provided with two first fixing brackets (12), and the two sides of the card compartment (3) are provided with second fixing brackets (13). The card compartment (3) has a test strip body (11) inside, and the top of the test strip body (11) is provided with two first locking blocks (14). The two sides of the test strip body (11) are provided with second locking blocks (15). The surfaces of the two first locking blocks (14) and the two second locking blocks (15) are provided with two guide rods (16). The exterior of the eight guide rods (16) is provided with a return spring (17). The top surfaces of the two second fixing frames (13) are provided with moving blocks (18), the card compartment (3) is provided with a screw (9) on one side, the card compartment (3) is provided with a guide rod (10) on the side away from the screw (9), the top of the card compartment (3) is provided with a fluorescence detector (4), the side of the fluorescence detector (4) away from the card compartment (3) is provided with a processor (5), the bottom of the processor (5) is provided with a battery (6), the middle of the battery (6) and the card compartment (3) is provided with a partition (7), the surface of the partition (7) near the card compartment (3) is provided with a guide rod (10), and the side of the screw (9) away from the moving block (18) is provided with a brushless motor (8).
2. The immunofluorescence test strip analysis device according to claim 1, characterized in that: The card compartment (3), fluorescence detector (4), processor (5), battery (6), partition (7), brushless motor (8), guide rod (16) and screw (9) are all located inside the analyzer (1). The card compartment (3) is installed inside the card slot (2). The fluorescence detector (4) and processor (5) are bolted to the analyzer (1), and the battery (6) is snapped into the analyzer (1). The partition (7) is integrally formed with the analyzer (1).
3. The immunofluorescence test strip analysis device according to claim 1, characterized in that: The two first fixing frames (12), the two second fixing frames (13), and the two moving blocks (18) are all integrally formed with the card compartment (3). The test strip body (11) is installed inside the card compartment (3). The two second fixing frames (13) and the two moving blocks (18) are all mirrored with the card compartment (3) as the center, and the positions of the two first fixing frames (12) correspond one-to-one.
4. The immunofluorescence test strip analysis device according to claim 1, characterized in that: The two first card blocks (14) and the two second card blocks (15) are all located inside the card compartment (3). The positions of the two first card blocks (14) correspond one-to-one with the positions of the two first fixing frames (12), and the positions of the two second card blocks (15) correspond one-to-one with the positions of the two second fixing frames (13).
5. The immunofluorescence test strip analysis device according to claim 1, characterized in that: Both first locking blocks (14) and two second locking blocks (15) are integrally formed with the two guide rods (16) on the surface, and the reset springs (17) are sleeved with the guide rods (16).
6. The immunofluorescence test strip analysis device according to claim 1, characterized in that: The two guide rods (16) on the surfaces of the two first card blocks (14) both penetrate the first fixing frame (12), and the two guide rods (16) on the surfaces of the two second card blocks (15) both penetrate the second fixing frame (13).
7. The immunofluorescence test strip analysis device according to claim 1, characterized in that: The guide rod (10) and the two brushless motors (8) are all bolted to the partition (7), and the positions of the guide rod (10) and the brushless motors (8) correspond one-to-one with the positions of the two moving blocks (18). The screw (9) is axially connected to the brushless motors (8), and one end of the screw (9) and the guide rod (10) both pass through the moving block (18).