An intelligent solid-phase extraction column activation device

Abstract

This utility model discloses an intelligent solid-phase extraction column activation device, including a vacuum chamber and a vacuum pump. A movable groove is provided at the bottom of the vacuum chamber, and a movable structure is provided within the movable groove. A sealing ring is fixedly connected to the upper surface of the vacuum chamber. Two snap-fit ​​holes are provided on the opposite side of the vacuum chamber. A cover plate is slidably connected to the upper surface of the vacuum chamber. This utility model, by incorporating a servo motor, threaded rod, movable block, movable box, waste liquid frame, sample tube rack, test tubes, waste liquid tank, and extraction tank, allows the servo motor to drive the movable block via the threaded rod before elution. The movable block then drives the movable box, which in turn moves the waste liquid frame and sample tube rack via the waste liquid tank and extraction tank, respectively. This moves multiple test tubes on the sample tube rack to the bottom of their corresponding outlet tubes, eliminating the need to open the cover plate to remove the waste liquid frame and then place it back into the sample tube rack. This simplifies operation and improves extraction efficiency.

Description

Technical Field

[0001] This utility model relates to the field of solid phase extraction technology, and in particular to an intelligent solid phase extraction column activation device. Background Technology

[0002] Solid-phase extraction column activation device is a system for pretreatment of solid-phase extraction columns. It activates the adsorbent through specific steps and components to optimize subsequent separation. Compared with traditional liquid-liquid extraction, solid-phase extraction column activation device is simpler to operate, saves time and effort, and can significantly improve the purity and recovery rate of analytes.

[0003] However, in existing equipment, the solution after activation, sample loading and rinsing needs to be collected in a waste liquid frame, and then the cover plate is opened to take out the waste liquid frame, the sample tube rack is placed in the vacuum chamber, and then the cover plate is closed again for elution. The operation of opening and closing the cover plate multiple times is cumbersome and affects the extraction efficiency. Therefore, an intelligent solid phase extraction column activation device is proposed. Utility Model Content

[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing an intelligent solid-phase extraction column activation device.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: an intelligent solid-phase extraction column activation device, comprising a vacuum chamber and a vacuum pump, wherein a movable groove is provided at the bottom of the vacuum chamber, a movable structure is provided in the movable groove, a sealing ring is fixedly connected to the upper surface of the vacuum chamber, two snap-fit ​​holes are provided on the opposite side of the vacuum chamber, a cover plate is slidably connected to the upper surface of the vacuum chamber, two quick-release components are provided on the cover plate, a plurality of first valve bodies are fixedly connected through the upper surface of the cover plate, a liquid outlet pipe is fixedly connected to the bottom of each first valve body, and an extraction column body is inserted into the liquid inlet end of each first valve body;

[0006] The moving structure includes a threaded rod rotatably connected inside the moving groove, and a servo motor is fixedly connected to the outer side of the vacuum chamber. The output shaft of the servo motor is fixedly connected to one end of the threaded rod.

[0007] As a further description of the above technical solution:

[0008] A movable block is threadedly connected to the threaded rod, and the movable block is slidably connected inside the movable groove.

[0009] As a further description of the above technical solution:

[0010] A movable box is fixedly connected to the upper surface of the movable block. A waste liquid tank and an extraction tank are provided on the upper surface of the movable box. A waste liquid frame is slidably connected inside the waste liquid tank. A sample tube rack is slidably connected inside the extraction tank. Test tubes are movably provided on the upper surface of the sample tube rack.

[0011] As a further description of the above technical solution:

[0012] The quick-release assembly includes a fixed frame fixedly connected to one side of the cover plate. Two sliding rods are fixedly connected to one side of the fixed frame. A movable plate is slidably connected to both sliding rods. Two snap-fit ​​posts are fixedly connected to one side of the movable plate. Each snap-fit ​​post is slidably connected through the cover plate to the corresponding side and is adapted to the corresponding snap-fit ​​hole.

[0013] As a further description of the above technical solution:

[0014] Each of the sliding rods is fitted with a spring, one end of each spring is fixedly connected to the inside side of the fixed frame, and the other end is fixedly connected to one side of the moving plate.

[0015] As a further description of the above technical solution:

[0016] A sliding column is fixedly connected to one side of the movable plate. One end of the sliding column is slidably connected to one side of the fixed frame and is rotatably connected to a fork. One side of the fork is in contact with the outer side of the fixed frame.

[0017] As a further description of the above technical solution:

[0018] The vacuum pump has a hose fixedly connected to its suction end, and a second valve is fixedly connected to one end of the hose. The suction port of the second valve extends to one side of the vacuum chamber and is fixedly connected thereto.

[0019] This utility model has the following beneficial effects:

[0020] 1. Compared with existing technologies, this intelligent solid-phase extraction column activation device, by setting up a servo motor, threaded rod, moving block, moving box, waste liquid frame, sample tube rack, test tubes, waste liquid tank, and extraction tank, etc., before elution, the servo motor drives the moving block to move via the threaded rod, the moving block drives the moving box to move, and the moving box drives the waste liquid frame and sample tube rack to move via the waste liquid tank and extraction tank, respectively. This allows multiple test tubes on the sample tube rack to move to the bottom of their corresponding outlet tubes. There is no need to open the cover to remove the waste liquid frame and then put it back into the sample tube rack, which makes the operation convenient and improves the extraction efficiency.

[0021] 2. Compared with existing technologies, this intelligent solid-phase extraction column activation device uses a fixed frame, sliding rod, moving plate, snap-fit ​​column, spring, sliding column and fork, etc. Moving the fork moves the moving plate through the sliding column. The moving plate moves the corresponding snap-fit ​​column out of the snap-fit ​​hole and compresses the spring, then opens the cover plate, which allows the staff to quickly remove the sample tube rack. Then the waste liquid frame is moved to the outlet of the vacuum chamber by the moving structure, and then the waste liquid frame is removed again to clean the waste liquid inside. Attached Figure Description

[0022] Figure 1 This is a three-dimensional structural diagram of an intelligent solid-phase extraction column activation device proposed in this utility model;

[0023] Figure 2 This is a plan view of an intelligent solid-phase extraction column activation device proposed in this utility model;

[0024] Figure 3 This is a cross-sectional view of an intelligent solid-phase extraction column activation device proposed in this utility model;

[0025] Figure 4 This is a schematic diagram of the moving structure of an intelligent solid-phase extraction column activation device proposed in this utility model;

[0026] Figure 5 This is an exploded view of the moving structure of an intelligent solid-phase extraction column activation device proposed in this utility model;

[0027] Figure 6 This is a schematic diagram of the quick-disassembly component of an intelligent solid-phase extraction column activation device proposed in this utility model;

[0028] Figure 7 Exploded view of the quick-disassembly component of an intelligent solid-phase extraction column activation device proposed in this utility model;

[0029] Figure 8 This is an exploded view of the vacuum chamber and sealing ring of an intelligent solid-phase extraction column activation device proposed in this utility model.

[0030] Legend:

[0031] 1. Vacuum chamber; 2. Moving tank; 3. Moving structure; 301. Servo motor; 302. Threaded rod; 303. Moving block; 304. Moving box; 305. Waste liquid frame; 306. Sample tube rack; 307. Test tube; 308. Waste liquid tank; 309. Extraction tank; 4. Sealing ring; 5. Cover plate; 6. Extraction column body; 7. Quick-release assembly; 701. Fixing frame; 702. Sliding rod; 703. Moving plate; 704. Snap-fit ​​column; 705. Spring; 706. Sliding column; 707. Fork; 8. Second valve; 9. Hoses; 10. Vacuum pump. Detailed Implementation

[0032] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0033] Reference Figures 1 to 8 This utility model provides an intelligent solid-phase extraction column activation device, which includes a vacuum chamber 1 and a vacuum pump 10. The suction end of the vacuum pump 10 is fixedly connected to a hose 9, and one end of the hose 9 is fixedly connected to a second valve 8. The suction port of the second valve 8 extends to the inside of the vacuum chamber 1 and is fixedly connected. A moving groove 2 is provided at the bottom of the vacuum chamber 1, and a moving structure 3 is provided in the moving groove 2. A sealing ring 4 is fixedly connected to the upper surface of the vacuum chamber 1. The sealing ring 4 can improve the sealing performance of the vacuum chamber 1. Two snap-fit ​​holes are provided on the opposite side of the vacuum chamber 1. A cover plate 5 is slidably connected to the upper surface of the vacuum chamber 1. Two quick-release components 7 are provided on the cover plate 5. Multiple first valve bodies are fixedly connected through the upper surface of the cover plate 5. A liquid outlet pipe is fixedly connected to the bottom of each first valve body. An extraction column body 6 is inserted into the liquid inlet end of each first valve body. A PLC control module is fixedly installed on one side of the vacuum chamber 1. The PLC control module is electrically connected to the servo motor 301 and the vacuum pump 10 to facilitate the control of the operation of the servo motor 301 and the vacuum pump 10.

[0034] To achieve the purpose of movement, the moving structure 3 includes a threaded rod 302 rotatably connected inside the moving groove 2. A servo motor 301 is fixedly connected to one side of the vacuum box 1. The output shaft of the servo motor 301 is fixedly connected to one end of the threaded rod 302. A moving block 303 is threadedly connected to the threaded rod 302. The moving block 303 is slidably connected inside the moving groove 2. A moving box 304 is fixedly connected to the upper surface of the moving block 303. A waste liquid tank 308 and an extraction tank 309 are provided on the upper surface of the moving box 304. A waste liquid frame 305 is slidably connected inside the waste liquid tank 308. The extraction tank 309 is located inside... A sample tube rack 306 is slidably connected, and test tubes 307 are movably mounted on the upper surface of the sample tube rack 306. Before elution, a servo motor 301 drives a moving block 303 to move via a threaded rod 302. The moving block 303 drives a moving box 304 to move. The moving box 304 drives a waste liquid frame 305 and a sample tube rack 306 to move via a waste liquid tank 308 and an extraction tank 309, respectively. This allows multiple test tubes 307 on the sample tube rack 306 to move to the bottom of their corresponding outlet tubes. There is no need to open the cover plate 5 to remove the waste liquid frame 305 and then put it back into the sample tube rack 306. This makes the operation convenient and improves the extraction efficiency.

[0035] To achieve rapid assembly and disassembly, the quick-release assembly 7 includes a fixed frame 701 fixedly connected to one side of the cover plate 5. Two sliding rods 702 are fixedly connected to one side of the fixed frame 701. A movable plate 703 is slidably connected to both sliding rods 702. A spring 705 is fitted onto each sliding rod 702. One end of each spring 705 is fixedly connected to the inside of the fixed frame 701, and the other end is fixedly connected to one side of the movable plate 703. Two locking posts 704 are fixedly connected to one side of the movable plate 703. Each locking post 704 is slidably connected through the corresponding side of the cover plate 5 and is adapted to a corresponding locking hole. A sliding column 706 is fixedly connected, with one end of the sliding column 706 slidably connected to one side of the fixed frame 701 and rotatably connected to a fork 707. One side of the fork 707 is in contact with the outer side of the fixed frame 701. After elution, the fork 707 is moved, and the fork 707 drives the moving plate 703 to move through the sliding column 706. The moving plate 703 drives the corresponding snap-fit ​​column 704 to disengage from the snap-fit ​​hole and compresses the spring 705. Then the cover plate 5 is opened to facilitate the staff to quickly remove the sample tube rack 306. Then the waste liquid frame 305 is moved to the discharge port of the vacuum chamber 1 through the moving structure 3. Then the waste liquid frame 305 is removed again to clean the waste liquid inside.

[0036] Working principle: Servo motor 301 drives moving block 303 via threaded rod 302, which in turn drives moving box 304. Moving box 304, through waste liquid tank 308 and extraction tank 309, drives waste liquid frame 305 and sample tube rack 306 respectively, moving waste liquid frame 305 to the bottom of multiple outlet tubes. Then, during activation, sample loading, and rinsing, the waste solution flows into waste liquid frame 305 through the outlet tubes. Before elution, servo motor 301 drives moving block 303 via threaded rod 302, which in turn drives moving box 304. Moving box 304, through waste liquid tank 308 and extraction tank 309, drives waste liquid frame 305 and sample tube rack respectively. The sample tube rack 306 is moved so that the multiple test tubes 307 on the sample tube rack 306 are moved to the bottom of the corresponding liquid outlet tubes. There is no need to open the cover plate 5 to take out the waste liquid frame 305 and then put it back into the sample tube rack 306. The operation is convenient and the extraction efficiency is improved. After elution, the fork 707 is turned. The fork 707 drives the moving plate 703 to move through the sliding column 706. The moving plate 703 drives the corresponding locking column 704 to disengage from the locking hole and compress the spring 705. Then the cover plate 5 is opened so that the staff can quickly take out the sample tube rack 306. Then the waste liquid frame 305 is moved to the discharge port of the vacuum box 1 through the moving structure 3. Then the waste liquid frame 305 is taken out again and the waste liquid inside is cleaned.

[0037] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. An intelligent solid-phase extraction column activation device, comprising a vacuum chamber (1) and a vacuum pump (10), characterized in that: The vacuum chamber (1) has a movable groove (2) at its inner bottom, and a movable structure (3) is provided in the movable groove (2). A sealing ring (4) is fixedly connected to the upper surface of the vacuum chamber (1). Two snap-fit ​​holes are provided on the opposite side of the vacuum chamber (1). A cover plate (5) is slidably connected to the upper surface of the vacuum chamber (1). Two quick-release components (7) are provided on the cover plate (5). Multiple first valve bodies are fixedly connected through the upper surface of the cover plate (5). A liquid outlet pipe is fixedly connected to the bottom of each first valve body. An extraction column body (6) is inserted into the liquid inlet end of each first valve body. The moving structure (3) includes a threaded rod (302) rotatably connected inside the moving groove (2). A servo motor (301) is fixedly connected to the outer side of the vacuum box (1). The output shaft of the servo motor (301) is fixedly connected to one end of the threaded rod (302).

2. The intelligent solid-phase extraction column activation device according to claim 1, characterized in that: The threaded rod (302) is threadedly connected to a movable block (303), which is slidably connected inside the movable groove (2).

3. The intelligent solid-phase extraction column activation device according to claim 2, characterized in that: A movable box (304) is fixedly connected to the upper surface of the movable block (303). A waste liquid tank (308) and an extraction tank (309) are provided on the upper surface of the movable box (304). A waste liquid frame (305) is slidably connected inside the waste liquid tank (308). A sample tube rack (306) is slidably connected inside the extraction tank (309). A test tube (307) is movably provided on the upper surface of the sample tube rack (306).

4. The intelligent solid-phase extraction column activation device according to claim 1, characterized in that: The quick-release assembly (7) includes a fixed frame (701) fixedly connected to one side of the cover plate (5). Two sliding rods (702) are fixedly connected to one side of the fixed frame (701). A moving plate (703) is slidably connected to both sliding rods (702). Two snap-fit ​​posts (704) are fixedly connected to one side of the moving plate (703). Each snap-fit ​​post (704) is slidably connected through the cover plate (5) on the corresponding side and is adapted to the corresponding snap-fit ​​hole.

5. The intelligent solid-phase extraction column activation device according to claim 4, characterized in that: Each of the sliding rods (702) is fitted with a spring (705), one end of each spring (705) is fixedly connected to one side of the inside of the fixed frame (701), and the other end is fixedly connected to one side of the moving plate (703).

6. The intelligent solid-phase extraction column activation device according to claim 4, characterized in that: A sliding column (706) is fixedly connected to one side of the movable plate (703). One end of the sliding column (706) is slidably connected to one side of the fixed frame (701) and is rotatably connected to a fork (707). One side of the fork (707) is in contact with the outer side of the fixed frame (701).

7. The intelligent solid-phase extraction column activation device according to claim 1, characterized in that: The vacuum pump (10) has a hose (9) fixedly connected to its suction end. One end of the hose (9) is fixedly connected to a second valve (8). The suction port of the second valve (8) extends to the inside of the vacuum chamber (1) and is fixedly connected.

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