Automatic filling device based on piperacillin sodium and tazobactam sodium powder for injection

Abstract

The utility model relates to filling device technical field especially for automatic filling device based on piperacillin sodium and tazobactam sodium medicine powder for injection, including conveying line and support drive package, support drive package one end installs the storage component, the inboard of storage component is installed and is smashed and is unloaded component, and the storage component includes storage shell, and the upper end fixed connection of storage shell has the unloading cylinder, and the upper end of storage shell is opened and has the discharge hole, and the lower end fixed connection of storage shell has the guide plate, and the smashed and unloaded component includes drive motor, and the drive motor main shaft end fixed connection has first extension shaft, and first extension shaft outside fixed connection has eccentric wheel and crushing knife, and the second extension shaft is installed to the crushing knife through the clutch, and second extension shaft outside fixed connection has spiral blade, in the utility model, the device can effectively solve the caking problem of medicine powder because of hygroscopicity, ensure the uniformity of medicine powder to realize the high accuracy ration filling, guarantee the consistency of medicine quality.

Description

Technical Field

[0001] This utility model relates to the field of filling device technology, specifically to an automatic filling device based on injectable piperacillin sodium tazobactam sodium powder. Background Technology

[0002] Piperacillin sodium and tazobactam sodium for injection is a compound antibiotic preparation composed of piperacillin and tazobactam. It enhances the antibacterial effect against a variety of enzyme-producing and drug-resistant bacteria by inhibiting bacterial cell wall synthesis and blocking enzymatic degradation. It is used clinically to treat moderate to severe infections and needs to be dissolved and administered intravenously.

[0003] Piperacillin sodium tazobactam sodium for injection is a sterile lyophilized powder, usually filled into glass vials for single-dose administration. These vials need to be dissolved with an appropriate diluent before clinical use, and then further diluted before being administered via intravenous infusion.

[0004] Piperacillin sodium has strong hygroscopic properties and easily absorbs moisture from the air, leading to localized clumping and increased density of the powder. This results in uneven overall powder density, making it difficult to achieve high-precision quantitative control during filling and causing variations in fill volume, ultimately affecting the consistency of drug quality. Therefore, to address the above problems, an automatic filling device based on injectable piperacillin sodium / tazobactam sodium powder is proposed. Utility Model Content

[0005] The purpose of this invention is to provide an automatic filling device based on injectable piperacillin sodium tazobactam sodium powder to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] An automatic filling device based on injectable piperacillin sodium / tazobactam sodium powder includes a conveyor line and a support drive assembly. A storage assembly is installed at one end of the support drive assembly, and a crushing and feeding assembly is installed inside the storage assembly. The storage assembly includes a storage shell, a feeding cylinder is fixedly connected to the upper end of the storage shell, a discharge hole is opened at the upper end of the storage shell, and a guide plate is fixedly connected to the lower end of the storage shell. The crushing and feeding assembly includes a drive motor, a first extension shaft is fixedly connected to the end of the drive motor main shaft, an eccentric wheel and a crushing blade are fixedly connected to the outside of the first extension shaft, a second extension shaft is installed on the crushing blade through a clutch, and a spiral blade is fixedly connected to the outside of the second extension shaft. The housing of the drive motor is fixedly connected to the bottom end of the storage shell, and the first extension shaft is rotatably connected to the inside of the storage shell.

[0008] As a further optimization of this utility model, the bracket drive assembly includes a bracket, a servo motor is fixedly connected to the left end of the bracket, a vertical plate is fixedly connected to the end of the servo motor spindle, the vertical plate is rotatably connected to the bracket via a shaft column, and a base plate is fixedly connected to the bottom end of the vertical plate.

[0009] As a further optimization of this utility model, a crossbar is fixedly connected between the two upright plates, an electric telescopic rod is fixedly connected to the side of the left upright plate near the crossbar, and a shaft frame is fixedly connected to the right side of the electric telescopic rod.

[0010] As a further optimization of this utility model, the crossbar is fitted with a spring on its outer side, and the bearing is rotatably connected to the inner side of the shaft frame. The bearing of the shaft frame and the eccentric wheel are on the same horizontal plane.

[0011] As a further optimization of this utility model, the conveyor line intersects with the support, and the feed cylinder is aligned vertically with the left end of the conveyor line.

[0012] As a further optimization of this utility model, the guide plate has a through hole on its inner side, and the guide plate is slidably connected to the crossbar through the through hole. Both the left and right sides of the guide plate are fixedly connected to springs. The upper and lower ends of the storage shell have rotating holes. The upper end of the storage shell has a feeding hole, and a rubber plug is installed inside the feeding hole of the storage shell.

[0013] As a further optimization of this utility model, the outer sides of both the first and second extension shafts are fixedly connected with sealing rings, and both the first and second extension shafts are sealed to the inside of the rotating hole of the storage shell through the sealing rings. The second extension shaft is rotatably connected to the inside of the rotating hole of the storage shell.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] In this invention, by setting up a support drive assembly, a material storage assembly, and a crushing and feeding assembly, the device integrates crushing and filling functions into one unit, reducing intermediate processes and improving the convenience of filling piperacillin sodium and tazobactam sodium powder. At the same time, through vibration and crushing action, it can effectively solve the problem of powder clumping caused by hygroscopicity, ensuring the uniformity of the powder, thereby achieving high-precision quantitative filling and ensuring the consistency of drug quality. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0017] Figure 2 This is a schematic diagram of the support drive assembly structure of this utility model;

[0018] Figure 3This is a schematic diagram of the shaft frame structure of this utility model;

[0019] Figure 4 This is a cross-sectional structural diagram of the material storage component of this utility model;

[0020] Figure 5 This utility model Figure 4 A schematic diagram of the structure at point A;

[0021] Figure 6 This is a schematic diagram of the crushing and feeding assembly of this utility model.

[0022] In the diagram: 1. Conveyor line;

[0023] 2. Bracket drive assembly; 21. Bracket; 22. Servo motor; 23. Base plate; 24. Vertical plate; 25. Electric telescopic rod; 26. Shaft bracket; 27. Crossbar; 28. Spring;

[0024] 3. Material storage assembly; 31. Material storage shell; 32. Feeding cylinder; 33. Discharge hole; 34. Guide plate;

[0025] 4. Crushing and feeding assembly; 41. Drive motor; 42. First extension shaft; 43. Eccentric wheel; 44. Crushing blade; 45. Clutch; 46. Second extension shaft; 47. Spiral blade. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0028] Please see Figures 1-6 This utility model provides a technical solution:

[0029] An automatic filling device based on injectable piperacillin sodium and tazobactam sodium powder includes a conveyor line 1 and a support drive assembly 2. A storage assembly 3 is installed at one end of the support drive assembly 2, and a crushing and feeding assembly 4 is installed inside the storage assembly 3. The storage assembly 3 includes a storage shell 31, a feeding cylinder 32 is fixedly connected to the upper end of the storage shell 31, a discharge hole 33 is opened at the upper end of the storage shell 31, and a guide plate 34 is fixedly connected to the lower end of the storage shell 31. The crushing and feeding assembly 4 includes a drive motor 41, a first extension shaft 42 is fixedly connected to the end of the main shaft of the drive motor 41, an eccentric wheel 43 and a crushing blade 44 are fixedly connected to the outside of the first extension shaft 42, a second extension shaft 46 is installed on the crushing blade 44 through a clutch 45, a spiral blade 47 is fixedly connected to the outside of the second extension shaft 46, the housing of the drive motor 41 is fixedly connected to the bottom end of the storage shell 31, and the first extension shaft 42 is rotatably connected to the inside of the storage shell 31.

[0030] As a further implementation of this solution, the support drive assembly 2 includes a support 21. A servo motor 22 is fixedly connected to the left end of the support 21. A vertical plate 24 is fixedly connected to the end of the main shaft of the servo motor 22. The vertical plate 24 is rotatably connected to the support 21 through a shaft column. A bottom plate 23 is fixedly connected to the bottom end of the vertical plate 24. With the above settings, the rotation drive of the entire material storage assembly 3 and the crushing and feeding assembly 4 can be realized, which provides convenience for smooth transfer and conveying during the filling process.

[0031] As a further implementation of this scheme, a crossbar 27 is fixedly connected between the two upright plates 24. An electric telescopic rod 25 is fixedly connected to the side of the left upright plate 24 near the crossbar 27. A shaft frame 26 is fixedly connected to the right side of the electric telescopic rod 25. A spring 28 is sleeved on the outside of the crossbar 27. A bearing is rotatably connected to the inside of the shaft frame 26. The bearing of the shaft frame 26 and the eccentric wheel 43 are on the same horizontal plane. Through the above arrangement, the electric telescopic rod 25 can control the position of the shaft frame 26, thereby controlling the vibration of the material storage assembly 3. The elastic force of the spring 28 plays the role of resetting the material storage assembly 3.

[0032] As a further implementation of this solution, the conveyor line 1 intersects with the support 21, and the discharge cylinder 32 is aligned vertically with the left end of the conveyor line 1. Through the above settings, it can be ensured that the powder is accurately filled into the glass vials, avoiding powder spillage or waste, and improving filling efficiency and drug utilization.

[0033] As a further implementation of this solution, a through hole is provided on the inner side of the guide plate 34. The guide plate 34 is slidably connected to the crossbar 27 through the through hole. Both the left and right sides of the guide plate 34 are fixedly connected to the spring 28. Rotating holes are provided at the upper and lower ends of the storage shell 31. A feeding hole is provided at the upper end of the storage shell 31. A rubber plug is installed inside the feeding hole of the storage shell 31. Through the above settings, the position of the guide plate 34 can be flexibly adjusted to ensure that the guide plate 34 slides smoothly on the crossbar 27. At the same time, the fixed connection between the guide plate 34 and the spring 28 can enhance the stability of the guide plate 34, avoid deviation or jamming during sliding, ensure the smoothness of the powder conveying process, and improve filling efficiency. Meanwhile, the feeding hole and rubber plug at the upper end of the storage shell 31 can facilitate the addition and sealing of the powder, prevent the powder from getting damp or contaminated, and ensure the quality of the powder.

[0034] As a further implementation of this solution, sealing rings are fixedly connected to the outer sides of both the first extension shaft 42 and the second extension shaft 46. Both the first extension shaft 42 and the second extension shaft 46 are sealed to the inside of the rotating hole of the storage shell 31 through the sealing rings. The second extension shaft 46 is rotatably connected to the inside of the rotating hole of the storage shell 31. Through the above arrangement, the sealing between the first extension shaft 42 and the second extension shaft 46 and the rotating hole of the storage shell 31 can be achieved, preventing leakage of the medicine powder during the transportation process, avoiding waste of medicine powder and environmental pollution, while ensuring the purity of the medicine powder during the transportation process, avoiding the mixing of external impurities, and ensuring the consistency and safety of the medicine quality.

[0035] Workflow: Before filling piperacillin sodium / tazobactam sodium powder, the uniformity of the powder needs to be controlled. First, the rubber stopper at the top of the storage shell 31 is removed. The piperacillin sodium / tazobactam sodium powder is added into the storage shell 31 until the material grinding clutch 45 is at the lower end of the spiral blade 47. After addition, the rubber stopper is reinstalled on the top of the storage shell 31. At this time, the drive motor 41 is started, driving the first extension shaft 42 to rotate. The clutch 45 is then engaged. In the "disengaged" state, the first extension shaft 42 rotates, causing the eccentric wheel 43 and the crushing blade 44 to rotate simultaneously. At the same time, the electric telescopic rod 25 is activated, moving the shaft frame 26 closer to the eccentric wheel 43. When the bearing on the shaft frame 26 moves to a designated distance, the eccentric wheel 43 rotates and contacts the bearing on the shaft frame 26. The bearing on the shaft frame 26 reduces the friction when the eccentric wheel 43 rotates. Simultaneously, the rotation of the eccentric wheel 43 causes the entire crushing and feeding assembly 4 to move left and right, thus creating a vibration effect on the crushing and feeding assembly 4. The action of the movement causes the clumps of material inside the storage shell 31 to settle downwards. The pulverizing blade 44 then pulverizes the clumps. When the material is pulverized to a certain extent, the servo motor 22 is activated, which drives the entire storage assembly 3 and the pulverizing and feeding assembly 4 to rotate via the vertical plate 24 and the bottom plate 23. When the feeding cylinder 32 faces the left end of the conveyor line 1, the clutch 45 is engaged, and the electric telescopic rod 25 drives the shaft frame 26 away from the eccentric wheel 43. At the same time, the first extension shaft 42 drives the clutch 45 and the second extension shaft 46 to move away from each other. The material is conveyed by the spiral blade 47 as it rotates simultaneously with the spiral blade 47. The conveyed material enters the feed cylinder 32 through the discharge hole 33 and then flows out from the feed cylinder 32, thus being filled into the glass vials on the conveyor line 1. Based on the above principles, the device can control the uniformity of piperacillin sodium tazobactam sodium powder during the filling process. The filling and crushing are integrated into one structure, reducing the transfer process, improving the convenience of filling piperacillin sodium tazobactam sodium powder, and ensuring the consistency of the final drug quality.

[0036] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An automated filling device based on piperacillin sodium / tazobactam sodium powder for injection, comprising a conveyor line (1) and a support drive assembly (2), characterized in that: One end of the support drive assembly (2) is equipped with a material storage assembly (3), and a crushing and feeding assembly (4) is installed inside the material storage assembly (3). The storage assembly (3) includes a storage shell (31), a feeding cylinder (32) is fixedly connected to the upper end of the storage shell (31), a discharge hole (33) is opened at the upper end of the storage shell (31), and a guide plate (34) is fixedly connected to the lower end of the storage shell (31). The crushing and feeding assembly (4) includes a drive motor (41), a first extension shaft (42) is fixedly connected to the end of the main shaft of the drive motor (41), an eccentric wheel (43) and a crushing blade (44) are fixedly connected to the outside of the first extension shaft (42), the crushing blade (44) is mounted with a second extension shaft (46) through a clutch (45), a spiral blade (47) is fixedly connected to the outside of the second extension shaft (46), and the housing of the drive motor (41) is fixedly connected to the bottom end of the storage shell (31); The first extension shaft (42) is rotatably connected to the inside of the storage shell (31).

2. The automatic filling device based on piperacillin sodium / tazobactam sodium powder for injection according to claim 1, characterized in that: The bracket drive assembly (2) includes a bracket (21), a servo motor (22) is fixedly connected to the left end of the bracket (21), a vertical plate (24) is fixedly connected to the end of the main shaft of the servo motor (22), the vertical plate (24) is rotatably connected to the bracket (21) through a shaft column, and a base plate (23) is fixedly connected to the bottom end of the vertical plate (24).

3. The automatic filling device based on piperacillin sodium / tazobactam sodium powder for injection according to claim 2, characterized in that: A crossbar (27) is fixedly connected between the two upright plates (24). An electric telescopic rod (25) is fixedly connected to the side of the left upright plate (24) near the crossbar (27). A shaft frame (26) is fixedly connected to the right side of the electric telescopic rod (25).

4. The automatic filling device based on piperacillin sodium / tazobactam sodium powder for injection according to claim 3, characterized in that: A spring (28) is sleeved on the outside of the crossbar (27), and a bearing is rotatably connected to the inside of the shaft frame (26). The bearing of the shaft frame (26) and the eccentric wheel (43) are on the same horizontal plane.

5. The automatic filling device based on piperacillin sodium / tazobactam sodium powder for injection according to claim 1, characterized in that: The conveyor line (1) intersects with the support (21), and the feed cylinder (32) is aligned vertically with the conveyor line (1) on the left.

6. The automatic filling device based on piperacillin sodium / tazobactam sodium powder for injection according to claim 1, characterized in that: The guide plate (34) has a through hole on its inner side. The guide plate (34) is slidably connected to the crossbar (27) through the through hole. The left and right sides of the guide plate (34) are fixedly connected to the spring (28). The upper and lower ends of the storage shell (31) are provided with rotating holes. The upper end of the storage shell (31) is provided with a feeding hole. A rubber plug is installed inside the feeding hole of the storage shell (31).

7. The automatic filling device based on piperacillin sodium / tazobactam sodium powder for injection according to claim 1, characterized in that: A sealing ring is fixedly connected to the outer side of the first extension shaft (42) and the second extension shaft (46). The first extension shaft (42) and the second extension shaft (46) are sealed to the inside of the rotating hole of the storage shell (31) through the sealing ring. The second extension shaft (46) is rotatably connected to the inside of the rotating hole of the storage shell (31).

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