A cyclic peptide membrane permeability observation device
By introducing components such as a moving block, a limiting mechanism, and a slider into the cyclic peptide membrane permeability observation device, the problems of laborious and unsafe movement of the device during movement are solved, achieving safe and convenient movement and stable observation.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- GUANGXI UNIV FOR NATITIES
- Filing Date
- 2025-07-17
- Publication Date
- 2026-07-07
AI Technical Summary
Existing cyclic peptide membrane permeability observation devices require manual handling during relocation, which is laborious and unsafe.
A device base was designed, comprising components such as a moving block, a limiting mechanism, a slider, and wheels. The slider and wheels enable automatic movement of the device, while the limiting mechanism and a fixing clamp secure the cyclic peptide membrane, ensuring the stability of the observation.
This enables the safe and convenient movement of the cyclic peptide membrane permeability observation device, improving the stability and practicality of the observation.
Smart Images
Figure CN224471531U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of cyclic peptide membrane observation, and in particular to a cyclic peptide membrane permeability observation device. Background Technology
[0002] Cyclic peptide membranes are thin film materials constructed with cyclic peptides as the core functional component. They combine the molecular recognition properties of cyclic peptides with the separation and barrier functions of membrane materials, and are mainly used in molecular sieving, substance separation, sensors, or biomedicine. In the research process, in order to accurately and quantitatively evaluate the permeability, selectivity, and dynamic processes of cyclic peptide membranes to different substances, permeability observation devices are required.
[0003] The existing technology has the following drawbacks: most existing cyclic peptide membrane permeability observation devices are placed on a platform. If the entire device needs to be moved to another location on the platform during subsequent use, it needs to be manually moved. Since the device itself has a certain weight, physical effort is required during the moving process, and care must be taken to handle it gently. Therefore, a cyclic peptide membrane permeability observation device is proposed to solve the above problems. Utility Model Content
[0004] To overcome the above shortcomings, this utility model provides a cyclic peptide membrane permeability observation device, which aims to improve the problem that existing cyclic peptide membrane permeability observation devices cannot be safely moved.
[0005] To achieve the above objectives, the present invention adopts the following technical solution: a cyclic peptide membrane permeability observation device, comprising a device base, a movable block slidably connected through the inner wall of the device base, a limiting mechanism provided on the inner wall of the movable block, a square block fixedly connected to the inner wall of the device base, a slider elastically connected to the top inner wall of the device base via a tension spring, a wheel provided at the bottom of the slider, multiple sets of sliders provided, the multiple sets of sliders connected to each other via a crossbar, a detection device provided at the top of the device base, a container provided at the top of the device base, and a fixing component provided on the inner wall of the container;
[0006] The limiting mechanism includes an L-shaped plate that passes through and is slidably connected to the inner wall of the moving block. The L-shaped plate is elastically connected to the moving block by a compression spring and is slidably connected to the left side of the block.
[0007] As a further description of the above technical solution:
[0008] The fixing assembly includes a fastening bolt that passes through and is threaded onto the inner wall of the container. A fixing clamp is rotatably connected to the right side of the fastening bolt. A round rod passes through and is slidably connected to the inner wall of the fixing clamp. A movable clamp is elastically connected to the fixing clamp via a helical spring.
[0009] As a further description of the above technical solution:
[0010] The top inner wall of the device base is fixedly connected to one end of the tension spring, and the other end of the tension spring is fixedly connected to the top of the slider.
[0011] As a further description of the above technical solution:
[0012] The bottom of the L-shaped plate is fixedly connected to one end of the compression spring, and the other end of the compression spring is fixedly connected to the bottom inner wall of the moving block.
[0013] As a further description of the above technical solution:
[0014] The right side of the slider contacts the left side of the moving block, and the slider is slidably connected to the inner wall of the device base.
[0015] As a further description of the above technical solution:
[0016] The right side of the fixed clamp is fixedly connected to one end of the helical spring, and the other end of the helical spring is fixedly connected to the left side of the movable clamp.
[0017] As a further description of the above technical solution:
[0018] The crossbar is slidably connected to the inner wall of the device base.
[0019] As a further description of the above technical solution:
[0020] The movable clamp is fixedly connected to the right side of the round rod.
[0021] This utility model has the following beneficial effects:
[0022] 1. In this utility model, by setting up moving blocks, L-shaped plates, sliders, wheels and other components, the wheels can be quickly exposed from the device and made to contact the ground, which facilitates the subsequent adjustment of the position of the entire device on the plane, thus changing the defect that some cyclic peptide membrane permeability observation devices cannot be moved safely.
[0023] 2. In this utility model, by rotating the fastening bolt, the fixed clamping plate and the moving clamping plate are moved toward the cyclic peptide membrane, which better fixes the cyclic peptide membrane in the container, ensures the stability of cyclic peptide membrane observation, and improves the practicality of the device. Attached Figure Description
[0024] Figure 1 This is a three-dimensional schematic diagram of the overall structure of the cyclic peptide membrane permeability observation device proposed in this utility model;
[0025] Figure 2This is a cross-sectional schematic diagram of the base of a cyclic peptide membrane permeability observation device proposed in this utility model;
[0026] Figure 3 This is a three-dimensional schematic diagram of the moving block, L-shaped plate, slider, wheel, tension spring and crossbar components of the cyclic peptide membrane permeability observation device proposed in this utility model;
[0027] Figure 4 This is a cross-sectional schematic diagram of the moving block of a cyclic peptide membrane permeability observation device proposed in this utility model;
[0028] Figure 5 This is a three-dimensional schematic diagram of the components of a cyclic peptide membrane permeability observation device proposed in this utility model, including a container, a fastening screw, a fixed clamping plate, a movable clamping plate, a helical spring, and a round rod.
[0029] Legend:
[0030] 1. Device base; 2. Moving block; 3. L-shaped plate; 4. Compression spring; 5. Square block; 6. Slider; 7. Wheel; 8. Tension spring; 9. Crossbar; 10. Detection device; 11. Container; 12. Fastening bolt; 13. Fixed clamp; 14. Moving clamp; 15. Helical spring; 16. Round rod. Detailed Implementation
[0031] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0032] Reference Figures 1-3This utility model provides an embodiment of a cyclic peptide membrane permeability observation device, including a device base 1. The entire device is a small observation device, which can be stored and used manually using wheels 7. A movable block 2 is slidably connected through the inner wall of the device base 1. A slot for the movable block 2 is opened on the surface of the device base 1 to allow the movable block 2 to move along the slot. A limit mechanism is provided on the inner wall of the movable block 2. A square block 5 is fixedly connected to the inner wall of the device base 1. The square block 5 can block the L-shaped plate 3 to prevent the movable block 2 from bouncing back. A slider 6 is elastically connected to the top inner wall of the device base 1 through a tension spring 8. The right side of the slider 6 is inclined. When the surface is squeezed, the slider 6 will move vertically. The bottom of the slider 6 is equipped with wheels 7, which can drive the entire device to move, saving manpower for handling. There are multiple sets of sliders 6, which are connected by crossbars 9. The crossbars 9 can connect multiple sliders 6 to ensure that multiple sliders 6 move at the same time. The top of the device base 1 is equipped with a detection device 10 and a container 11. The container 11 is made of stainless steel to prevent contamination when in contact with the cyclic peptide membrane. The container 11 is a detachable part on the device base 1, and the inner wall of the container 11 is equipped with fixing components.
[0033] The limiting mechanism includes an L-shaped plate 3, which is L-shaped and slidably connected to the inner wall of the moving block 2. The surface of the moving block 2 has a corresponding groove for the L-shaped plate 3, which allows the L-shaped plate 3 to move along the groove. The L-shaped plate 3 is elastically connected to the moving block 2 by a compression spring 4. When the L-shaped plate 3 is pressed down, it will compress the compression spring 4. When it is reset, the compression spring 4 will reset the L-shaped plate 3. The L-shaped plate 3 is slidably connected to the left side of the block 5, which can fix the wheel 7 and prevent it from rebounding when the moving device is in motion.
[0034] Reference Figure 5The fixing assembly includes a fastening bolt 12, which is threaded through and connected to the inner wall of the container 11. The surface of the container 11 has a corresponding slot for the fastening bolt 12, allowing the fastening bolt 12 to move along the slot. A fixing plate 13 is rotatably connected to the right side of the fastening bolt 12, allowing the fixing plate 13 to move parallel. A round rod 16 is slidably connected through the inner wall of the fixing plate 13. The surface of the fixing plate 13 has a corresponding slot for the round rod 16, allowing the round rod 16 to move along the slot. The fixing plate 13... The helical spring 15 is elastically connected to a movable clamping plate 14. The movable clamping plate 14 is made of stainless steel, which is highly corrosion-resistant and can prevent rust from contaminating the cyclic peptide membrane. The right side of the fixed clamping plate 13 is fixedly connected to one end of the helical spring 15, and the other end of the helical spring 15 is fixedly connected to the left side of the movable clamping plate 14. When the movable clamping plate 14 is subjected to force and moves outward, it will compress the helical spring 15. When resetting, the helical spring 15 drives the movable clamping plate 14 to reset. The movable clamping plate 14 is fixedly connected to the right side of the round rod 16, which allows the movable clamping plate 14 to move parallel.
[0035] Reference Figures 2-4 The top inner wall of the device base 1 is fixedly connected to one end of the tension spring 8, and the other end of the tension spring 8 is fixedly connected to the top of the slider 6. When the slider 6 moves downward, it will stretch the tension spring 8. When resetting, the tension spring 8 will bring the slider 6 back to its original position. The right side of the slider 6 is in contact with the left side of the moving block 2. The slider 6 is slidably connected to the inner wall of the device base 1, so that the wheel 7 can be taken out and retracted. The crossbar 9 is slidably connected to the inner wall of the device base 1. The inner wall of the device base 1 has a corresponding groove for the crossbar 9, which can satisfy the crossbar 9 to move along the groove.
[0036] Working principle: First, when the entire device needs to be moved, press the L-shaped plate 3 downwards to make it enter the interior of the moving block 2, push the moving block 2 to the left, and the moving block 2 will press the inclined surface of the slider 6 to make it move downwards, so that the wheel 7 exceeds the bottom of the device base 1. Release the L-shaped plate 3 to make it pop out and lock its upper half on the left side of the block 5, so that the moving block 2 will not be forced to bounce back. Move the observation device by the wheel 7. When retracting the wheel 7, simply press the L-shaped plate 3 downwards to make it enter the interior of the moving block 2, pull the moving block 2 to the right to reset it, the slider 6 loses the downward pressing force of the moving block 2, the tension spring 8 drives the slider 6 to reset and the wheel 7 retracts. When the moving block 2 resets, release the L-shaped plate 3 to make it pop out, and the retraction is completed.
[0037] When it is necessary to fix the cyclic peptide membrane, the fixing plate 13 and the moving plate 14 can be moved toward the cyclic peptide membrane by rotating the fastening bolt 12. When the moving plate 14 touches the cyclic peptide membrane, it will be subjected to force and will compress the helical spring 15. The reverse elastic force of the helical spring 15 will be used to keep the moving plate 14 in contact with the surface of the cyclic peptide membrane. After the observation is completed, the fastening bolt 12 can be rotated in the opposite direction to loosen the moving plate 14 from the cyclic peptide membrane, and then the cyclic peptide membrane can be removed.
[0038] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A device for observing the permeability of cyclic peptide membranes, comprising a device base (1), characterized in that: The inner wall of the device base (1) is slidably connected to a moving block (2), the inner wall of the moving block (2) is provided with a limit mechanism, the inner wall of the device base (1) is fixedly connected to a block (5), the top inner wall of the device base (1) is elastically connected to a slider (6) by a tension spring (8), the bottom of the slider (6) is provided with a wheel (7), the slider (6) is provided with multiple sets, the multiple sets of sliders (6) are connected by a crossbar (9), the top of the device base (1) is provided with a detection device (10), the top of the device base (1) is provided with a container (11), the inner wall of the container (11) is provided with a fixing component; The limiting mechanism includes an L-shaped plate (3), which is slidably connected to the inner wall of the moving block (2). The L-shaped plate (3) is elastically connected to the moving block (2) by a compression spring (4), and the L-shaped plate (3) is slidably connected to the left side of the block (5).
2. The cyclic peptide membrane permeability observation device according to claim 1, characterized in that: The fixing assembly includes a fastening bolt (12) that is threaded through and connected to the inner wall of the container (11). A fixing clamp (13) is rotatably connected to the right side of the fastening bolt (12). A round rod (16) is slidably connected through the inner wall of the fixing clamp (13). A movable clamp (14) is elastically connected to the fixing clamp (13) by a helical spring (15).
3. The cyclic peptide membrane permeability observation device according to claim 1, characterized in that: The top inner wall of the device base (1) is fixedly connected to one end of the tension spring (8), and the other end of the tension spring (8) is fixedly connected to the top of the slider (6).
4. The cyclic peptide membrane permeability observation device according to claim 1, characterized in that: The bottom of the L-shaped plate (3) is fixedly connected to one end of the compression spring (4), and the other end of the compression spring (4) is fixedly connected to the bottom inner wall of the moving block (2).
5. The cyclic peptide membrane permeability observation device according to claim 1, characterized in that: The right side of the slider (6) contacts the left side of the moving block (2), and the slider (6) is slidably connected to the inner wall of the device base (1).
6. The cyclic peptide membrane permeability observation device according to claim 2, characterized in that: The right side of the fixed clamp (13) is fixedly connected to one end of the helical spring (15), and the other end of the helical spring (15) is fixedly connected to the left side of the movable clamp (14).
7. The cyclic peptide membrane permeability observation device according to claim 1, characterized in that: The crossbar (9) is slidably connected to the inner wall of the device base (1).
8. The cyclic peptide membrane permeability observation device according to claim 2, characterized in that: The movable clamp (14) is fixedly connected to the right side of the round rod (16).