一种高血脂样本血清微型分离装置
By designing a micro-separation device for hyperlipidemic serum samples, using a 0.22 μm filter membrane and external pressure from a pressure device, fat particles and lipoproteins in hyperlipidemic blood can be effectively removed. This solves the dilution error and hemolysis problems in the processing of hyperlipidemic blood samples in existing technologies, and improves the accuracy and ease of operation of biochemical indicator detection.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- ZHEJIANG UNIV
- Filing Date
- 2025-06-11
- Publication Date
- 2026-07-17
AI Technical Summary
Existing technologies for processing hyperlipidemic samples present risks of dilution error and protein denaturation with chemical methods, while physical methods require high-performance centrifuges and may lead to hemolysis, affecting the accuracy of biochemical indicator detection.
A micro-separation device for high blood lipid samples was designed, which combines a pressure device, a filter and a collector. By optimizing the pore size of the filter membrane to 0.22 μm, external pressure is applied by the pressure device to remove fat particles and lipoproteins, thus avoiding damage to biochemical indicators.
It improves the accuracy of biochemical indicator detection, simplifies the operation process, reduces equipment costs, and does not affect the biochemical indicator components in serum.
Smart Images
Figure CN224506754U_ABST
Abstract
Claims
1. A hyperlipidemic sample serum micro-separation device, characterized by, The device includes a pressure device, a filter, and a collector. The filter has a first interface at the top and a second interface at the bottom. The first interface is connected to the pressure device, and the second interface is connected to the collector. The filter has a filter membrane inside.
2. The apparatus of claim 1, wherein, The collector includes an adapter, a collection tube, and a base. The adapter includes a third interface and a base plate. The third interface is connected to a second interface at the bottom of the filter. The base plate has multiple vent holes.
3. The apparatus of claim 1, wherein, The filter membrane has a pore size of 0.22 μm and an internal volume of 50~100 μL.
4. The apparatus of claim 1, wherein, The pressure device includes a push rod and a metering cylinder. The metering cylinder includes an inlet and an outlet. The push rod includes a handle, a squeezing end, and a connecting rod. The handle is located at the inlet of the metering cylinder, and the squeezing end is located inside the metering cylinder.
5. The apparatus of claim 4, wherein, The collection tube includes a tube body and a cap. The outer side of the tube body opening and the inner side of the cap are threaded, and the thread of the collection tube opening is compatible with the thread of the cap.
6. The apparatus of claim 5, wherein, The diameter of the first interface of the filter is larger than the diameter of the second interface.
7. The apparatus of claim 6, wherein, The outlet diameter of the metering cylinder is adapted to the first interface diameter of the filter, and the second interface diameter of the filter is adapted to the third interface diameter of the adapter.
8. The apparatus of claim 7, wherein, The bottom of the collection tube is conical, and the diameter of the tube is adapted to the diameter of the base.
9. The apparatus of claim 8, wherein, The diameter of the collecting tube is smaller than the diameter of the adapter base plate.
10. The apparatus of claim 9, wherein, The filter is spindle-shaped.