Dual lumen dialysis catheter based on end-side connection

Abstract

The application discloses a double-lumen dialysis catheter based on end-side connection, relates to the technical field of medical devices, and comprises a catheter main body, an arterial end catheter and a venous end catheter. A partition wall is arranged in the catheter main body and extends along the length direction of the catheter main body; the internal space of the catheter main body is separated into a first cavity and a second cavity which are independent of each other by the partition wall. One end of the arterial end catheter is connected to one end of the catheter main body, and the internal space of the arterial end catheter is in communication with the first cavity. One end of the venous end catheter is connected to one end of the catheter main body, the venous end catheter and the arterial end catheter are connected to the same end of the catheter main body, and the internal space of the venous end catheter is in communication with the second cavity. The length of the venous end catheter is greater than that of the arterial end catheter. The venous end catheter is arranged at an included angle with the catheter main body. The dialysis catheter based on end-side connection optimizes hemodynamics, reduces pressure gradient and recirculation rate, reduces blood vessel wall contact, realizes long-term blood flow smoothness and gives consideration to blood vessel protection.

Description

Technical Field

[0001] This application relates to the field of medical device technology, specifically to a dual-lumen dialysis catheter based on end-side connection. Background Technology

[0002] Hemodialysis is a crucial treatment for chronic renal failure, requiring a vascular access catheter to provide a stable blood flow during the process. Currently, commonly used central venous catheters (CVCs) employ an "end-to-end" design, where the catheter tip is inserted deep into the target vein (such as the superior vena cava or atrium) to ensure blood flow. However, this design has significant drawbacks:

[0003] 1. Narrow side holes or tip channels increase blood flow resistance, and blood extraction and reinfusion require a high pressure gradient (approximately 1 mmHg / cm or 100-200 mmHg total pressure), which puts a burden on dialysis equipment and blood vessels;

[0004] 2. The arterial and venous ports of the catheter are located close to each other, which makes recirculation more likely and reduces dialysis efficiency;

[0005] 3. The catheter is in extensive contact with the blood vessel wall. The dynamic friction generated by cardiopulmonary exercise can damage the endothelium, form a fibrous sheath, and obstruct blood flow, leading to decreased blood flow susceptibility and requiring frequent use of thrombolytic agents or catheter replacement.

[0006] Therefore, there is an urgent need for a new type of dialysis catheter that can solve the fundamental problems of high pressure gradient, high recirculation rate and vascular damage while ensuring blood flow. Utility Model Content

[0007] This application provides a dual-lumen dialysis catheter based on end-side connection to solve the problems existing in the prior art.

[0008] This application provides a dual-lumen dialysis catheter based on end-to-side connection, comprising a catheter body, an arterial end catheter, and a venous end catheter. A partition wall is disposed within the catheter body, extending along the length of the catheter body, dividing the internal space of the catheter body into a first cavity and a second cavity. One end of the arterial end catheter is connected to one end of the catheter body, and the internal space of the arterial end catheter communicates with the first cavity. One end of the venous end catheter is connected to one end of the catheter body, and the venous end catheter and the arterial end catheter are connected to the same end of the catheter body; the internal space of the venous end catheter communicates with the second cavity; the length of the venous end catheter is greater than the length of the arterial end catheter; the venous end catheter is positioned at an angle to the catheter body.

[0009] In one specific feasible implementation, the outer diameter of the catheter body is 4-5 mm.

[0010] In one specific implementation, the inner diameter of the first cavity is 1.8-2.2 mm, and the inner diameter of the second cavity is 1.8-2.2 mm.

[0011] In one specific implementation, the total length of the catheter body and the venous end catheter is 8-10 cm.

[0012] In one specific feasible implementation, the inner diameter of the venous catheter is 1.8-2.2 mm.

[0013] In one specific implementation, the angle between the venous end catheter and the catheter body is α, where 30°≤α≤45°.

[0014] In one specific implementation, the other end of the venous catheter is provided with an arc-shaped chamfer, the radius of which is 0.5-1mm.

[0015] In one specific implementation, the length difference between the arterial end catheter and the venous end catheter is 10-15 mm.

[0016] In one specific implementation, the inner diameter of the arterial end catheter is 1.8-2.2 mm.

[0017] In one specific implementation, the other end of the arterial catheter is trumpet-shaped.

[0018] In one specific implementation, a positioning ring is fitted around the outside of the catheter body, the positioning ring being slidable relative to the catheter body; at least a portion of the surface of the positioning ring is a rough surface; the dimension of the positioning ring along the length direction of the catheter body is 5-10 mm.

[0019] In one specific implementation scheme, the inner wall of the conduit body is provided with a first mounting groove and a second mounting groove, the first mounting groove and the second mounting groove extending along the length direction of the conduit body respectively, and the first mounting groove and the second mounting groove are spaced apart in the circumferential direction of the conduit body; the partition wall is inserted into the first mounting groove and the second mounting groove.

[0020] In one specific implementation scheme, the first mounting groove has a U-shaped cross-section along the radial direction of the conduit body, and the second mounting groove has a U-shaped cross-section along the radial direction of the conduit body; the end face of the partition wall that is inserted into the first mounting groove is U-shaped, and the end face of the partition wall that is inserted into the second mounting groove is U-shaped.

[0021] Compared with the prior art, the beneficial effects of this application are as follows:

[0022] The dual-lumen dialysis catheter based on end-to-side connection provided in this application allows the arterial end catheter to utilize the relatively wide blood flow channel at the junction of the tributary vein and the target vein to achieve multi-directional blood flow inflow, mimicking natural blood flow inflow and reducing the resistance of blood being drawn out from the arterial end catheter. At the same time, the venous end catheter, which is set at an angle to the catheter body, can point downstream of the target vein and can be returned downstream, reducing the resistance of blood being returned from the venous end catheter to the vein. The synergistic effect of the arterial end catheter and the venous end catheter can reduce the pressure gradient.

[0023] The length of the venous catheter is greater than that of the arterial catheter, and the venous catheter is set at an angle to the main body of the catheter. This can extend the blood outflow path and the blood return path, keep the recirculation rate at a low level, and improve dialysis efficiency.

[0024] End-to-side connection can be used, which allows blood to be drawn out through the wide blood flow channel at the junction and to be returned downstream of the target vein, thus ensuring smooth blood flow for a relatively long period of time. On the other hand, it can also protect blood vessels, reduce contact with the vessel wall, reduce endothelial damage, and lower the risk of fibrosis and thrombosis. Attached Figure Description

[0025] Figure 1 This paper shows a schematic diagram of the structure of a dual-lumen dialysis catheter based on end-side connection provided in an embodiment of this application;

[0026] Figure 2 A schematic cross-sectional view of the catheter body of a dual-lumen dialysis catheter based on end-side connection provided in an embodiment of this application is shown along its radial direction.

[0027] Figure 3 This illustration shows a cross-sectional view of the catheter body of the dual-lumen dialysis catheter based on end-side connection provided in this application after the partition wall has been removed.

[0028] Figure label:

[0029] 1-Catheter body; 11-First cavity; 12-Second cavity; 13-First mounting groove; 14-Second mounting groove; 2-Arterial end catheter; 3-Venous end catheter; 4-Separation wall; 5-Positioning ring; 6-Branch vein; 7-Target vein. Detailed Implementation

[0030] To make the objectives, technical solutions, and advantages of this application clearer, the embodiments of this application will be described in further detail below with reference to the accompanying drawings. However, the exemplary embodiments can be implemented in many forms and should not be construed as limited to the embodiments set forth herein. The same reference numerals in the figures denote the same or similar structures, and therefore repeated descriptions of them will be omitted. The terms expressing position and direction described in the embodiments of this application are illustrative based on the accompanying drawings, but changes can be made as needed, and all such changes are included within the scope of protection of this application. The accompanying drawings of the embodiments of this application are only for illustrating relative positional relationships and do not represent actual scale.

[0031] Specific details are set forth in the following description to aid in understanding this application; however, embodiments of this application can be implemented in various ways other than those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the embodiments of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0032] As one possible application scenario, the dual-lumen dialysis catheter based on end-side connection provided in this application embodiment can be used in hemodialysis to provide dialysis patients with stable blood flow, reduce complications, and has clear medical application value.

[0033] First refer to Figure 1 , Figure 1 A schematic diagram of the structure of a dual-lumen dialysis catheter based on end-side connection provided in an embodiment of this application is shown. Figure 1 As shown, the dual-lumen dialysis catheter based on end-to-side connection provided in this application embodiment may include a catheter body 1, an arterial end catheter 2, and a venous end catheter 3. Figure 2 This illustration shows a radial cross-sectional view of the catheter body of a dual-lumen dialysis catheter based on end-side connection, as provided in an embodiment of this application. Figure 2 As shown, a partition wall 4 is provided inside the catheter body 1. The partition wall 4 extends along the length direction of the catheter body 1 and the length of the partition wall 4 is the same as the length of the catheter body 1. The internal space of the catheter body 1 is divided into a first cavity 11 and a second cavity 12 that are independent of each other by the partition wall 4.

[0034] One end of the arterial catheter 2 is connected to one end of the catheter body 1, and the internal space of the arterial catheter 2 communicates with the first cavity 11. One end of the venous catheter 3 is connected to one end of the catheter body 1, and the venous catheter 3 and the arterial catheter 2 are connected to the same end of the catheter body 1. The internal space of the venous catheter 3 communicates with the second cavity 12. The length of the venous catheter 3 can be greater than the length of the arterial catheter 2, and the venous catheter 3 and the catheter body 1 can be set at an angle.

[0035] The dual-lumen dialysis catheter based on end-to-side connection provided in this application embodiment can be inserted into the patient's tributary vein 6 (such as the right internal jugular vein) in practical application. The port of the arterial end catheter 2 (the opening at the end of the arterial end catheter 2 that is not connected to the catheter body 1) is positioned at the junction of the tributary vein 6 and the target vein 7 (such as the brachiocephalic vein), and penetrates the target vein 7 to a certain length (such as 2-5 mm). Since the venous end catheter 3 is set at an angle to the catheter body 1, that is, the venous end catheter 3 is pre-bent, the port of the venous end catheter 3 (the opening at the end of the venous end catheter 3 that is not connected to the catheter body 1) can point downstream of the target vein 7. The port of the catheter body 1 (the opening at the end of the catheter body 1 that is not connected to the arterial end catheter 2 and the venous end catheter 3) is connected to the dialysis equipment, thereby realizing the flow of blood between the patient and the dialysis equipment, thus realizing hemodialysis.

[0036] The unique structural design of this dialysis catheter allows for an end-to-side connection. The arterial end catheter 2 is located at the junction of the tributary vein 6 and the target vein 7. This allows for multi-directional blood flow through the relatively wide blood flow channel (approximately 10-15 mm in diameter), reducing resistance to blood flow into the arterial end catheter 2 and facilitating blood extraction from the vein to the dialysis device via the arterial end catheter 2 and the first cavity 11 of the catheter body 1. Simultaneously, the venous end catheter 3, angled to the catheter body 1 and pointing downstream of the target vein 7, allows blood returned from the dialysis device to flow downstream along the main blood flow direction of the target vein 7, reducing return resistance. Furthermore, the venous end catheter 3 is longer than the arterial end catheter 2, effectively separating the blood extraction and return paths and minimizing the risk of recirculation.

[0037] This dialysis catheter can achieve the following technical effects:

[0038] Arterial catheter 2 can utilize the relatively wide blood flow channel at the junction of tributary vein 6 and target vein 7 to achieve multi-directional blood flow, mimicking natural blood flow and reducing the resistance of blood flowing out of arterial catheter 2. At the same time, venous catheter 3, which is set at an angle to the catheter body 1, can point downstream of the target vein 7 and can be returned downstream, reducing the resistance of blood returning from venous catheter 3 to the vein. The synergistic effect of arterial catheter 2 and venous catheter 3 can reduce the pressure gradient.

[0039] The length of the venous catheter 3 is greater than that of the arterial catheter 2, and the venous catheter 3 is set at an angle to the catheter body 1. This can extend the blood outflow path and the blood return path, keep the recirculation rate at a low level, and improve dialysis efficiency.

[0040] End-to-side connection can be used. On the one hand, the wide blood flow channel at the junction can be used to draw out blood and to return it downstream of the target vein 7, which can ensure smooth blood flow for a relatively long time. On the other hand, it can also protect blood vessels, reduce contact with the blood vessel wall, reduce endothelial damage, and reduce the risk of fibrosis and thrombosis.

[0041] Overall, this dialysis catheter is based on end-to-side connection. The arterial end catheter 2 is placed at the junction of the tributary vein 6 and the target vein 7, and the venous end catheter 3 is pre-bent and pointed downstream of the target vein 7. This optimizes hemodynamics, reduces pressure gradient and recirculation rate, reduces vascular wall contact, achieves long-term blood flow patency while protecting blood vessels, and solves the problems of high pressure gradient, high recirculation rate and vascular damage in hemodialysis therapy.

[0042] In practice, the catheter body 1 can be made of biocompatible materials, such as silicone or polyurethane. The outer diameter of the catheter body 1 can be 4-5 mm, the inner diameter of the first cavity 11 can be 1.8-2.2 mm, and the inner diameter of the second cavity 12 can be 1.8-2.2 mm. The catheter body 1 is connected to the dialysis device, and a blood flow rate of 200-350 ml / min can be achieved during hemodialysis.

[0043] The total length of the catheter body 1 and the venous end catheter 3 can be 8-10 cm. The length of the venous end catheter 3 can be 3-5 cm. The venous end catheter 3 and the catheter body 1 can be connected by a threaded structure, or the venous end catheter 3 and the catheter body 1 can be sleeved and interference-fitted, or the venous end catheter 3 and the catheter body 1 can be integrally formed. The inner diameter of the venous end catheter 3 can be 1.8-2.2 mm. The included angle between the venous end catheter 3 and the catheter body 1 is α, exemplarily 30°≤α≤45°, realizing the pre-bent setting of the venous end catheter 3. The end of the venous end catheter 3 connected to the catheter body 1 has a bent section with a fixed shape, so that the venous end catheter 3 can maintain the included angle α. The other end of the venous end catheter 3 (the end not connected to the catheter body 1) can be provided with an arc-shaped chamfer, the radius of which can be 0.5-1 mm, and the chamfer can be formed by molding. The chamfered design can reduce endothelial damage and reduce shear force and turbulence during blood return. The chamfered design, together with the pre-bent venous end catheter 3, can further optimize hemodynamics and ensure long-term unobstructed blood flow.

[0044] The length difference between the arterial end catheter 2 and the venous end catheter 3 can be 10-15 mm. The arterial end catheter 2 and the catheter body 1 can be connected by a threaded structure, or the arterial end catheter 2 and the catheter body 1 can be sleeved and interference-fitted, or the arterial end catheter 2 and the catheter body 1 can be integrally molded. The inner diameter of the arterial end catheter 2 can be 1.8-2.2 mm. The other end of the arterial end catheter 2 (the end not connected to the catheter body 1) can be funnel-shaped, which can further reduce the resistance of blood flow into the port of the arterial end catheter 2, making it easier for blood to flow into the arterial end catheter 2 and facilitating the drainage of blood from the vein to the dialysis device.

[0045] In practical implementation, a positioning ring 5 can be fitted onto the outside of the catheter body 1. In actual application, the positioning ring 5 is fixed subcutaneously, for example, 5-10 cm from the skin inlet, thus securing the dialysis catheter to the subcutaneous tissue and tributary vein 6. The positioning ring 5 is slidably connected to the catheter body 1, allowing it to slide relative to the catheter body 1, facilitating adjustment of the dialysis catheter's position according to clinical conditions. The positioning ring 5 can have a length of 5-10 mm along the length of the catheter body 1, meaning its width can be 5-10 mm. The positioning ring 5 can be made of materials such as polyester, and at least a portion of its surface can be roughened to promote tissue ingrowth, thus improving the positional stability of the positioning ring 5 and consequently, the overall positional stability of the dialysis catheter.

[0046] In one possible embodiment, the catheter body 1, the venous end catheter 3, and the arterial end catheter 2 are all made of silicone. The outer diameter of the catheter body 1 is 4 mm, and the inner diameters of the first cavity 11 and the second cavity 12 are 1.9 mm, respectively. The total length of the catheter body 1 and the venous end catheter 3 is 8 cm. The inner diameter of the venous end catheter 3 is 1.9 mm, the angle α between the venous end catheter 3 and the catheter body 1 is 45°, and the radius of the chamfer at the end of the venous end catheter 3 is 0.5 mm. The length of the arterial end catheter 2 is 10 mm shorter than the length of the venous end catheter 3, and the inner diameter of the arterial end catheter 2 is 1.9 mm. The positioning ring 5 is made of polyester and has a width of 5 mm. In practical applications, the port of the arterial end catheter 2 mm penetrates into the junction of the right internal jugular vein and the brachiocephalic vein, while the venous end catheter 3 points downstream of the brachiocephalic vein.

[0047] Figure 3 This illustration shows a cross-sectional view of the catheter body after the partition wall has been removed, representing an embodiment of the dual-lumen dialysis catheter based on end-side connection provided in this application. Figure 3As shown, the inner wall of the catheter body 1 may be provided with a first mounting groove 13 and a second mounting groove 14. The first mounting groove 13 and the second mounting groove 14 extend along the length direction of the catheter body 1, and are spaced apart in the circumferential direction of the catheter body 1. A partition wall 4 is inserted into the first mounting groove 13 and the second mounting groove 14, dividing the internal space of the catheter body 1 into two independent cavities 11 and 12. The partition wall 4 is detachably connected to the catheter body 1, so that the partition wall 4 can be removed from the inside of the catheter body 1 according to the actual clinical situation, making the catheter body 1 a single-lumen structure, thereby increasing the flexibility of the application of this dialysis catheter. For example, when the catheter body 1 of this dialysis catheter is a single-lumen structure, it can be used for time-sharing blood outflow and inflow operations.

[0048] In specific implementation, the first mounting groove 13 can have a U-shaped cross-section along the radial direction of the conduit body 1, that is, the first mounting groove 13 has a U-shaped opening on the cross-section along the radial direction of the conduit body 1. The second mounting groove 14 can also have a U-shaped cross-section along the radial direction of the conduit body 1. Correspondingly, the end face of the partition wall 4 that is inserted into the first mounting groove 13 is U-shaped, and the end face of the partition wall 4 that is inserted into the second mounting groove 14 is U-shaped. The position of the partition wall 4 inside the conduit body 1 is relatively stable, and the disassembly of the partition wall 4 is also relatively convenient.

[0049] The above are merely specific embodiments of this application, but the scope of protection of this application is not limited to the above embodiments. Obviously, those skilled in the art can make various modifications and variations to this application without departing from the scope and spirit of this application. If these modifications and variations fall within the scope of the claims of this application and their equivalents, then the intent of this application also includes these modifications and variations.

Claims

1. A dual-lumen dialysis catheter based on end-side connection, characterized in that, It includes the catheter body, the arterial end catheter, and the venous end catheter; The catheter body is provided with a partition wall that extends along the length of the catheter body, and the internal space of the catheter body is divided into a first cavity and a second cavity by the partition wall. One end of the arterial end catheter is connected to one end of the catheter body, and the internal space of the arterial end catheter is in communication with the first cavity; One end of the venous catheter is connected to one end of the catheter body, and the venous catheter and the arterial catheter are connected to the same end of the catheter body. The internal space of the venous catheter is in communication with the second cavity. The length of the venous catheter is greater than the length of the arterial catheter. The venous catheter and the catheter body are set at an angle.

2. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The outer diameter of the catheter body is 4-5 mm.

3. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The inner diameter of the first cavity is 1.8-2.2 mm, and the inner diameter of the second cavity is 1.8-2.2 mm.

4. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The total length of the catheter body and the venous end catheter is 8-10 cm.

5. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The inner diameter of the venous catheter is 1.8-2.2 mm.

6. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The angle between the venous end catheter and the catheter body is α, where 30°≤α≤45°.

7. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The other end of the venous catheter is provided with an arc-shaped chamfer with a radius of 0.5-1mm.

8. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The length difference between the arterial end catheter and the venous end catheter is 10-15 mm.

9. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The inner diameter of the arterial end catheter is 1.8-2.2 mm.

10. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The other end of the arterial catheter is trumpet-shaped.

11. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, A positioning ring is fitted around the outside of the catheter body, and the positioning ring can slide relative to the catheter body. At least a portion of the surface of the positioning ring is a rough surface; The positioning ring has a dimension of 5-10 mm along the length of the catheter body.

12. The dual-lumen dialysis catheter based on end-side connection according to claim 1, characterized in that, The inner wall of the catheter body is provided with a first mounting groove and a second mounting groove. The first mounting groove and the second mounting groove extend along the length direction of the catheter body, and the first mounting groove and the second mounting groove are spaced apart in the circumferential direction of the catheter body. The partition wall is inserted into the first mounting slot and the second mounting slot.

13. The dual-lumen dialysis catheter based on end-side connection according to claim 12, characterized in that, The first mounting groove has a U-shaped cross-section along the radial direction of the conduit body, and the second mounting groove has a U-shaped cross-section along the radial direction of the conduit body; The end face of the partition wall that is inserted into the first mounting slot is U-shaped, and the end face of the partition wall that is inserted into the second mounting slot is U-shaped.

Images