Blood radioactivity decay detector

Abstract

The application discloses a blood radioactivity decay detector, and relates to the field of medical care information processing equipment, and comprises a detector body and a neck collar, wherein the neck collar is in a semi-enclosing structure, the neck collar is used for being mounted on the neck of a human body, the detector body is detachably connected with the neck collar, the neck collar is provided with a mounting hole for the detector body to pass through, and one end of the detector body is used for abutting against the neck of the human body; a tension connecting piece is connected between two end portions of the neck collar, and the tension connecting piece is detachably connected with one end of the neck collar. When the blood radioactivity of the human body is detected for multiple times continuously, the detector body does not need to be repeatedly positioned to the carotid artery of the human body, and the application is more convenient and efficient.

Description

Technical Field

[0001] This application relates to the field of healthcare information processing equipment, and more particularly to a blood radioactive decay detector. Background Technology

[0002] Pharmacokinetics, or pharmacodynamics for short, primarily studies the dynamic changes in how the body processes drugs. This includes the absorption, distribution, biochemical transformation (or metabolism), and excretion of drugs within the body, particularly the changes in blood drug concentration over time.

[0003] A blood radioactivity analyzer is a detection instrument suitable for real-time measurement of blood radioactivity in pharmacokinetics. By measuring the arterial input function (AIF) and combining it with data images obtained from PET scans, the analyzer uses PMOD software for kinetic modeling and image analysis to determine the metabolic status of radioactive substances in the in vivo. The blood radioactivity analyzer is of great significance for determining various parameters in pharmacokinetics and provides important guidance for clinical drug evaluation and efficacy assessment.

[0004] Blood radioactivity detectors are suitable for small laboratory animals and humans. When used with arteriovenous shunts, blood does not need to be drawn out of the body during measurement, making the test more convenient. However, since blood radioactivity testing usually requires multiple consecutive measurements, the blood radioactivity detector must be aimed at the carotid artery of the human body for each measurement, which is cumbersome and inconvenient. Summary of the Invention

[0005] To address the inconvenience of repeatedly aligning the blood radioactivity detector with the carotid artery during multiple consecutive tests, this application provides a blood radioactivity decay detector.

[0006] The blood radioactive decay detector provided in this application adopts the following technical solution: A blood radioactive decay detector includes a detector body and a neck clamp. The neck clamp has a semi-enclosed structure and is used to be installed on the neck of a human body. The detector body is detachably connected to the neck clamp. The neck clamp has an installation hole for the detector body to pass through. One end of the detector body is used to abut against the neck of a human body. A tensioning connector is connected between the two ends of the neck clamp, and the tensioning connector is detachably connected to one end of the neck clamp.

[0007] By adopting the above technical solution, when using the blood radioactive decay detector, a neck brace is worn around the subject's neck. After the neck brace is worn, it is tightened using a tensioning connector. The detector body is detachably mounted on the neck brace, and one end of the detector body rests against the neck under the tension of the tensioning connector, allowing the detector body to detect the radioactive decay in the blood of the carotid artery. During the detection process, the detector body remains mounted on the neck brace, keeping its position on the subject's neck constant and ensuring it remains aligned with the carotid artery. When performing multiple consecutive blood radioactivity tests, it is not necessary to repeatedly position the detector body against the carotid artery, making it convenient and efficient.

[0008] Optionally, the neck clamp is provided with an annular mounting seat, which is installed in the mounting hole; the detector body is fitted with a connecting sleeve, which has an external thread, and the annular mounting seat has an internal thread that matches the external thread.

[0009] By adopting the above technical solution, when the detector body is installed on the neck brace, it is first installed on the connecting sleeve, and then the connecting sleeve is threaded to the annular mounting seat. By causing the connecting sleeve and the annular mounting seat to rotate relative to each other, the detector body can be moved closer to or away from the human neck, thereby changing the tightness of contact between the detector body and the human neck. The external thread is set on the connecting sleeve, and the structure where the external thread is located needs to have a large wall thickness. The material of the connecting sleeve can be relatively lightweight materials such as plastic or aluminum alloy. In this case, the outer shell of the detector body can be set as a thin-walled steel structure, which is beneficial to controlling the weight of the detector body.

[0010] Optionally, the detector body has a detection end at one end that abuts against the neck of the human body, and a wiring end at the other end. The wiring end of the detector body is inserted into the connecting sleeve. A limiting protrusion is provided circumferentially on the inner wall of the end of the connecting sleeve away from the detection end of the detector body. The limiting protrusion is used to abut against the wiring end of the detector body.

[0011] By adopting the above technical solution, the limiting protrusion has a limiting effect on the relative position between the detector body and the connecting sleeve, making it difficult for the detector body to move relative to the connecting sleeve under the push of the reverse force of the human neck.

[0012] Optionally, the connecting sleeve includes two arc-shaped half-section plates, which are combined to form a cylindrical structure; one of the two arc-shaped half-section plates is designated as the first half-section plate and the other as the second half-section plate, and a hinge is formed between the straight edge of the first half-section plate and the straight edge of the second half-section plate.

[0013] By adopting the above technical solution, the connecting sleeve is formed by combining two arc-shaped half-section plates, making it easier for the detector body to be installed inside the connecting sleeve; the external thread on the outer circumference of the connecting sleeve is formed on both the first and second half-section plates, and the first and second half-section plates are hinged, so that the relative positions of the first and second half-section plates along the length direction are relatively fixed, thereby making the external thread on the outer surface of the connecting sleeve as continuous and smooth as possible, which is conducive to smoother relative helical movement between the connecting sleeve and the annular mounting seat.

[0014] Optionally, the first half-section plate has a plurality of continuously arranged first insert teeth on its edge away from the hinge side, and the second half-section plate has a plurality of continuously arranged second insert teeth on its edge away from the hinge side. The second insert teeth are staggered and adapted to the first insert teeth. The first insert teeth are provided with a first pin hole, and the second insert teeth are provided with a second pin hole. Both the first pin hole and the second pin hole are through holes, and the length direction of both the first pin hole and the second pin hole is along the axial direction of the connecting sleeve. The plurality of first insert teeth and the plurality of second insert teeth are connected to a pin through the first pin hole and the second pin hole.

[0015] By adopting the above technical solution, the first insert on the first half-section plate and the second insert on the second half-section plate are staggered and adapted, which helps to further stabilize the relative position of the first half-section plate and the second half-section plate along the length direction; and the first insert on the first half-section plate and the second insert on the second half-section plate are connected by pins, making it difficult for the second half-section plate to open up to each other, thereby forming a reliable connection between the first half-section plate and the second half-section plate.

[0016] Optionally, the annular mounting base and the mounting hole form a rotatable connection; the outer peripheral surface of the connecting sleeve is provided with a guide groove along the axial direction, and a guide member is provided on the outer side of the neck clamp, and the guide member and the guide groove are slidably connected along the extension direction of the guide groove.

[0017] By adopting the above technical solution, the connecting sleeve and the neck clamp form a sliding connection through the guide groove and guide component. When the annular mounting seat rotates, the annular mounting seat and the connecting sleeve move in a relative spiral motion, thereby forcing the connecting sleeve and the detector body to slide closer to or away from the human neck. During this process, the detector body does not need to rotate around its own axis, making it less likely for the guide connecting the detector body to be twisted. This helps to reduce the resistance during the position adjustment process of the detector body and also helps to reduce the damage of the wires due to long-term torsional deformation.

[0018] Optionally, the annular mounting base includes a tubular body, with a limiting flange at one end of the tubular body away from the center of the neck clamp, the limiting flange abutting against the outer edge of the mounting hole, a limiting snap ring at one end of the tubular body away from the limiting flange, and a snap ring groove on the outer circumferential surface of the tubular body for engaging the limiting snap ring.

[0019] By adopting the above technical solution, the limiting flange and the limiting snap ring together restrict the axial relative position between the annular mounting seat and the mounting hole, allowing the annular mounting seat to rotate only relative to the mounting hole. A detachable connection is formed between the limiting snap ring and the snap ring groove of the annular mounting seat, allowing the annular mounting seat to be assembled and disassembled as needed.

[0020] Optionally, the surface of the limiting flange facing away from the center of the neck clamp is provided with an indexing mark in the circumferential direction.

[0021] By adopting the above technical solution, when the annular mounting seat rotates, the rotation angle of the annular mounting seat can be determined by observing the indexing marks on the limiting flange, thereby determining the distance that the detector body moves relative to the neck hoop along the axial direction.

[0022] Optionally, the guide includes a guide portion and a connecting portion, both of which are sheet-like structures. The outer side of the neck clamp is provided with a positioning groove that is adapted to the connecting portion. The positioning groove communicates with the mounting hole, and the limiting flange abuts against the connecting portion.

[0023] By adopting the above technical solution, the connecting part of the guide is installed in the positioning groove, and the limiting flange of the annular mounting seat abuts against the connecting part to prevent the connecting part from coming out of the positioning groove, thereby positioning the guide.

[0024] Optionally, the connecting part is an annular structure, the tubular body passes through the connecting part, and the outer contour of the connecting part is elliptical; two guide parts are provided, and they are respectively located at both ends of the long axis of the connecting part.

[0025] By adopting the above technical solution, the connecting part is set as an annular structure with an elliptical outer contour, which can realize the positioning of the connecting part by using the positioning groove, and at the same time make the binding force of the positioning groove on the connecting part more balanced; and the tubular body passes through the connecting part, and the limiting flange can keep abutting the guide part throughout the entire circumference, making the installation state of the guide part more stable; the guide member forms a guiding effect on the connecting sleeve through two symmetrically arranged guide parts, making the guiding effect of the guide member on the connecting sleeve more reliable.

[0026] In summary, this application includes at least one of the following beneficial technical effects: 1. During the detection process, the detector body is installed on the neck brace, keeping the detector body in a constant position on the subject's neck and keeping it aligned with the carotid artery. When performing multiple consecutive blood radioactivity tests, it is not necessary to repeatedly position the detector body to the carotid artery, which is more convenient and efficient.

[0027] 2. The connecting sleeve and the neck clamp form a sliding connection through the guide groove and guide component. The detector body does not need to rotate around its own axis, which makes it less likely for the guide connecting the detector body to be twisted. This helps to reduce the resistance during the position adjustment process of the detector body and also helps to reduce the damage of the wire due to long-term torsional deformation. Attached Figure Description

[0028] Figure 1 This is a schematic diagram of the overall structure of this embodiment.

[0029] Figure 2 This is a cross-sectional view used in this embodiment to illustrate the positional relationship between the detector body and the mounting hole.

[0030] Figure 3 This is an exploded view used in this embodiment to illustrate the connection relationship between the detector body and the annular mounting base.

[0031] Figure 4 This is a structural schematic diagram illustrating the open state of the connecting sleeve in this embodiment.

[0032] Explanation of reference numerals in the attached figures: 1. Detector body; 2. Neck clamp; 21. Mounting hole; 22. Elastic abutment; 23. Positioning groove; 3. Tensioning connector; 31. Elastic band; 32. Hook and loop fastener; 4. Annular mounting base; 41. Tubular body; 42. Limiting flange; 421. Indexing mark; 43. Limiting snap ring; 44. Snap ring groove; 5. Connecting sleeve; 50. Arc-shaped half-section plate; 51. First half-section plate; 511. First insert tooth; 512. First pin hole; 52. Second half-section plate; 521. Second insert tooth; 522. Second pin hole; 53. Pin; 531. Pin head; 54. Connecting groove; 55. Guide groove; 56. Limiting protrusion; 6. Guide component; 61. Connecting part; 62. Guide part. Detailed Implementation

[0033] The following is in conjunction with the appendix Figure 1-4 This application will be described in further detail.

[0034] This application discloses a blood radioactive decay detector. (Refer to...) Figure 1 and Figure 2The blood radioactive decay detector includes a detector body 1, a neck collar 2, and a tensioning connector 3. The neck collar 2 has a semi-enclosed structure and is used to be installed on the human neck. The detector body 1 uses a high-sensitivity SIPM detector as its detection element, and the scintillator is a LYSO crystal, with interference shielded by a tungsten alloy shield. The detector body 1 and the neck collar 2 are detachably connected. The neck collar 2 has a mounting hole 21 through which the detector body 1 passes. One end of the detector body 1 is used to abut against the human neck, and the end of the detector body 1 used to abut against the human neck is the detection end, while the other end is the wiring end. The tensioning connector 3 connects both ends of the neck collar 2, and the tensioning connector 3 and one end of the neck collar 2 form a detachable connection.

[0035] Reference Figure 1 The neck brace 2 is an elastic plastic component. Two elastic abutment members 22 are provided on the concave side of the middle part of the neck brace 2, arranged sequentially along the length of the neck brace 2. The elastic abutment members 22 are made of silicone. When the neck brace 2 is installed on the neck, the elastic abutment members 22 are under pressure and deformation, which helps to keep the neck brace 2 taut.

[0036] Reference Figure 1 The tensioning connector 3 is an elastic band 31. One end of the elastic band 31 is fixedly connected to one end of the neck clamp 2, and the other end of the elastic band 31 is connected to the other end of the neck clamp 2 by a hook and loop fastener 32.

[0037] Reference Figure 2 and Figure 3 The neck clamp 2 is provided with an annular mounting seat 4, which is installed in the mounting hole 21; the instrument body 1 is provided with a connecting sleeve 5, which is made of lightweight materials such as plastic or aluminum alloy. The connecting sleeve 5 is provided with an external thread, and the annular mounting seat 4 is provided with an internal thread that matches the external thread.

[0038] Reference Figure 2 and Figure 3 The wiring terminal of the detector body 1 is inserted into the connecting sleeve 5. A limiting protrusion 56 is provided circumferentially on the inner wall of the end of the connecting sleeve 5 furthest from the detection end of the detector body 1. The limiting protrusion 56 is used to abut against the wiring terminal of the detector body 1. Under the limiting action of the limiting protrusion 56, when the detector body 1 abuts against the human neck, the detector body 1 is not easily moved relative to the connecting sleeve 5 under the reverse force of the human neck.

[0039] Reference Figure 3 and Figure 4 The connecting sleeve 5 includes two arc-shaped half-section plates 50, which are combined to form a cylindrical structure. One of the two arc-shaped half-section plates 50 is designated as the first half-section plate 51, and the other is designated as the second half-section plate 52. The straight edge of the first half-section plate 51 and the straight edge of the second half-section plate 52 are hinged together.

[0040] The first half-section plate 51 has a plurality of continuously arranged first insert teeth 511 on its edge away from the hinge side, and the second half-section plate 52 has a plurality of continuously arranged second insert teeth 521 on its edge away from the hinge side. The second insert teeth 521 are staggered and adapted to the first insert teeth 511. The first insert teeth 511 are provided with a first pin hole 512, and the second insert teeth 521 are provided with a second pin hole 522. Both the first pin hole 512 and the second pin hole 522 are through holes, and the length direction of both the first pin hole 512 and the second pin hole 522 is along the axial direction of the connecting sleeve 5.

[0041] Multiple first insert teeth 511 and multiple second insert teeth 521 pass through a first pin hole 512 and a second pin hole 522 together to provide a pin 53. The pin 53 has a needle-like structure, with a pin head 531 at one end. The diameter of the pin head 531 is larger than the diameter of the first pin hole 512 and the diameter of the second pin hole 522. The end of the pin 53 away from the pin head 531 is set as a pointed tip so that the pin 53 can be more easily inserted into the first pin hole 512 and the second pin hole 522.

[0042] Both of the two arc-shaped half-section plates 50 are provided with rubber damping layers on their concave sides. The arc-shaped half-section plates 50 abut against the outer circumference of the detector body 1 through the rubber damping layers. When the two arc-shaped half-section plates 50 are in the closed state, the rubber damping layers are in the pre-compression deformation state, making the connection between the detector body 1 and the connecting sleeve 5 more stable.

[0043] Reference Figure 2 and Figure 3 The annular mounting base 4 and the mounting hole 21 form a rotatable connection. A guide groove 55 is axially formed on the outer circumferential surface of the connecting sleeve 5, with both ends of the guide groove 55 passing through it. An external thread runs through the guide groove 55 along the axial direction of the connecting sleeve 5. A guide member 6 is provided on the outer side of the neck clamp 2, and the guide member 6 is slidably connected to the guide groove 55 along its extension direction. The connecting sleeve 5 and the neck clamp 2 form a sliding fit through the guide groove 55 and the guide member 6. When the annular mounting base 4 rotates, the internal thread of the annular mounting base 4 meshes with the external thread of the connecting sleeve 5, forcing the connecting sleeve 5 to slide closer to or away from the human neck.

[0044] Reference Figure 3 The annular mounting base 4 includes a tubular body 41. A limiting flange 42 is provided at one end of the tubular body 41 away from the center of the neck clamp 2. The limiting flange 42 abuts against the outer edge of the opening of the mounting hole 21. An indexing mark 421 is provided circumferentially on the surface of the limiting flange 42 away from the center of the neck clamp 2. The indexing mark 421 is a recessed engraving line. A limiting snap ring 43 is provided at one end of the tubular body 41 away from the limiting flange 42. A snap ring groove 44 for engaging the limiting snap ring 43 is provided on the outer circumferential surface of the tubular body 41. The limiting flange 42 and the limiting snap ring 43 together limit the axial position of the annular mounting base 4.

[0045] When it is necessary to move the detector body 1 closer to or further away from the human neck, this can be done by rotating the limiting flange 42. Additionally, by observing the change in the rotation angle of the graduation mark 421 on the limiting flange 42, the sliding adjustment distance of the connecting sleeve 5 can be determined. Furthermore, when the operator of the detector needs to rotate the annular mounting base 4, they can place their finger against the area of ​​the graduation mark 421 and use friction to rotate the annular mounting base 4.

[0046] Reference Figure 3 The guide member 6 includes a connecting part 61 and two guide parts 62. Both the connecting part 61 and the guide parts 62 are thin sheet structures. The connecting part 61 is an annular structure and is sleeved on the tubular body 41. The inner hole of the connecting part 61 is a round hole, and the outer contour of the connecting part 61 is elliptical. The outer side of the neck clamp 2 is provided with a positioning groove 23 that is adapted to the connecting part 61. The positioning groove 23 communicates with the mounting hole 21. The limiting flange 42 abuts against the connecting part 61, so that the connecting part 61 is positioned.

[0047] Two guide portions 62 are located at both ends of the long axis of the connecting portion 61 and are symmetrically arranged along the short axis of the guide portions 62. The guide member 6 is slidably connected to the connecting sleeve 5 through the two guide portions 62, so that the guide member 6 provides a relatively reliable guiding effect on the connecting sleeve 5. The surface of the guide portion 62 is parallel to the long axis of the connecting portion 61, and the guide portion 62 can be used as a reference object for the rotational movement angle of the indexing mark 421.

[0048] The implementation principle of a blood radioactive decay detector according to an embodiment of this application is as follows: When using the blood radioactive decay detector, a neck brace 2 is worn around the neck of the subject. After the neck brace 2 is worn, it is tightened using a tensioning connector 3 to make the neck brace 2 as tight as possible. The detector body 1 is detachably installed on the neck brace 2. At the same time, by rotating the annular mounting base 4, the detector body 1 can be brought close to and pressed against the human neck, allowing the detector body 1 to detect the radioactive decay in the blood of the human carotid artery. During the detection process, the position of the detector body 1 on the subject's neck remains unchanged, eliminating the need to repeatedly position the detector body 1 to the human carotid artery, which is more convenient and efficient.

[0049] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A blood radioactive decay detector, characterized in that: The device includes a detector body (1) and a neck brace (2). The neck brace (2) has a semi-enclosed structure and is used to be installed on the neck of a human body. The detector body (1) and the neck brace (2) are detachably connected. The neck brace (2) has an installation hole (21) through which the detector body (1) passes. One end of the detector body (1) is used to abut against the neck of a human body. A tensioning connector (3) is connected between the two ends of the neck brace (2). The tensioning connector (3) and one end of the neck brace (2) are detachably connected. The neck clamp (2) is provided with an annular mounting seat (4), which is installed in the mounting hole (21); the detector body (1) is fitted with a connecting sleeve (5), which is provided with an external thread, and the annular mounting seat (4) is provided with an internal thread that is compatible with the external thread; The annular mounting base (4) and the mounting hole (21) are rotatably connected; the outer circumferential surface of the connecting sleeve (5) is provided with a guide groove (55) along the axial direction; the outer side of the neck clamp (2) is provided with a guide member (6); the guide member (6) and the guide groove (55) are slidably connected along the extension direction of the guide groove (55).

2. The blood radioactive decay detector according to claim 1, characterized in that: The detector body (1) has a detection end at one end that abuts against the neck of the human body and a wiring end at the other end. The wiring end of the detector body (1) is inserted into the connecting sleeve (5). The inner wall of the connecting sleeve (5) at the end away from the detection end of the detector body (1) is provided with a limiting protrusion (56) along the circumference. The limiting protrusion (56) is used to abut against the wiring end of the detector body (1).

3. The blood radioactive decay detector according to claim 2, characterized in that: The connecting sleeve (5) includes two arc-shaped half-section plates (50), which are combined to form a cylindrical structure; one of the two arc-shaped half-section plates (50) is designated as the first half-section plate (51), and the other is designated as the second half-section plate (52), and the straight side of the first half-section plate (51) and the straight side of the second half-section plate (52) are hinged together.

4. A blood radioactive decay detector according to claim 3, characterized in that: The first half-section plate (51) has a plurality of continuously arranged first insert teeth (511) on its edge away from the hinge side, and the second half-section plate (52) has a plurality of continuously arranged second insert teeth (521) on its edge away from the hinge side. The second insert teeth (521) are staggered and adapted to the first insert teeth (511). The first insert teeth (511) are provided with a first pin hole (512), and the second insert teeth (521) are provided with a second pin hole (522). The first pin hole (512) and the second pin hole (522) are both through holes. The length direction of the first pin hole (512) and the second pin hole (522) are both along the axial direction of the connecting sleeve (5). The plurality of first insert teeth (511) and the plurality of second insert teeth (521) are connected by a pin (53) through the first pin hole (512) and the second pin hole (522).

5. A blood radioactive decay detector according to claim 1, characterized in that: The annular mounting base (4) includes a tubular body (41). The end of the tubular body (41) away from the center of the neck clamp (2) is provided with a limiting flange (42). The limiting flange (42) abuts against the outer edge of the opening of the mounting hole (21). The end of the tubular body (41) away from the limiting flange (42) is provided with a limiting snap ring (43). The outer circumferential surface of the tubular body (41) is provided with a snap ring groove (44) for snapping the limiting snap ring (43).

6. A blood radioactive decay detector according to claim 5, characterized in that: The limiting flange (42) has an indexing mark (421) on its surface away from the center of the neck band (2) along the circumferential direction.

7. A blood radioactive decay detector according to claim 5, characterized in that: The guide (6) includes a guide part (62) and a connecting part (61). Both the connecting part (61) and the guide part (62) are thin sheet structures. The outer side of the neck band (2) is provided with a positioning groove (23) that is adapted to the connecting part (61). The positioning groove (23) communicates with the mounting hole (21). The limiting flange (42) abuts against the connecting part (61).

8. A blood radioactive decay detector according to claim 7, characterized in that: The connecting part (61) is a ring structure, the tubular body (41) passes through the connecting part (61), and the outer contour of the connecting part (61) is elliptical; there are two guide parts (62), which are located at the two ends of the long axis of the connecting part (61).

Images