Prefilled syringe flame processing apparatus and processing equipment

Abstract

The application relates to a pre-filled syringe flame processing device and a processing equipment, the pre-filled syringe flame processing device comprises a cutting assembly and a blow-through assembly, the cutting assembly comprises a cutting torch for spraying a plurality of parallel flames, the cutting torch is arranged before a separation station of a pre-filled syringe forming equipment and is aligned with a cutting position of a glass tube; the blow-through assembly comprises a blow-through torch for spraying a single flame, the blow-through torch is arranged after the separation station of the pre-filled syringe forming equipment and is aligned with two closed ends of the glass tube after being cut by the flame; wherein the cutting torch and the blow-through torch are connected with an external hydrogen source. The application uses a flame cutting mode to replace a mechanical cutting mode, the cutting process does not cause mechanical vibration to the glass tube, the cutting quality is high and the material is uniformly separated, meanwhile, the torch does not cause abrasion, does not need to be adjusted, maintained and stopped, the cutting quality is stable and efficient, the cutting quality and the production efficiency of the pre-filled syringe are improved, and the torch uses hydrogen as energy, which is more environmentally friendly.

Description

Technical Field

[0001] This application relates to the technical field of pharmaceutical neutral borosilicate pre-filling equipment, and more specifically, to a flame processing device and processing equipment for pre-filled syringes. Background Technology

[0002] With the development of pharmaceutical packaging materials, pre-filled syringes have become a preferred packaging method for many high-end drugs due to their advantages such as pre-sealed drugs, single use, reduced risk of contamination, and simplified injection process. Pre-filled syringes have strict requirements for dimensional processing. Most existing pre-filling production equipment uses a mechanical cutter to cut the glass tube during production to further manufacture the pre-filled syringe. However, mechanical cutters are prone to cutting defects, resulting in uneven cut surfaces and gaps in the glass tube, leading to uneven material distribution and ultimately, substandard dimensions of the pre-filled syringe after molding. Furthermore, mechanical cutters are constantly wearing down, requiring continuous feed adjustments. Failure to adjust in a timely manner can result in poor cutting, making subsequent processing incompatible and affecting product quality. Utility Model Content

[0003] This application provides a flame processing device and equipment for pre-filled syringes to solve the problems in the prior art of using a mechanical cutter to cut glass tubes to make pre-filled syringes. Due to the uneven cut surface and uneven material distribution of the mechanical cutter, as well as the problems of wear and inconvenience in adjustment, the production quality and efficiency of pre-filled syringes are affected.

[0004] A flame processing apparatus for pre-filled syringes according to this application includes:

[0005] The cutting assembly includes a cutting nozzle that sprays multiple parallel flames. The cutting nozzle is positioned before the separation station of the pre-filled syringe molding equipment and is aimed at the part of the glass tube to be cut.

[0006] The blow-through assembly includes a blow-through nozzle that sprays a single beam of flame. The blow-through nozzle is located after the separation station of the pre-filled syringe molding equipment and is respectively aimed at the two ends of the glass tube that are sealed after being cut by the flame.

[0007] Both the cutting nozzle and the blowing nozzle are connected to an external hydrogen gas source.

[0008] In some embodiments, multiple sets of cutting nozzles are provided, and the multiple sets of cutting nozzles are arranged sequentially from front to back before the separation station of the pre-filled syringe forming equipment, and the multiple sets of cutting nozzles together heat the same part of the glass tube to be cut.

[0009] In some embodiments, the flame intensity of each cutting nozzle increases progressively from front to back.

[0010] In some embodiments, the cutting nozzle consists of one or more parallel ten-hole nozzles, with a flame hole at the top of the parallel ten-hole nozzle and an air supply port at the rear side of the parallel ten-hole nozzle.

[0011] In some embodiments, the diameter of the flame holes of the parallel ten-hole nozzle is 0.3 mm.

[0012] In some embodiments, the blow-through assembly is provided with at least two blow-through nozzles, one of which is vertically upward and aligned with the closed bottom of the glass tube, and the other is vertically downward and aligned with the closed top of the glass tube.

[0013] In some embodiments, two blow-through nozzles are respectively located at different stations behind the separation station of the pre-filled syringe molding equipment.

[0014] In some embodiments, the blow nozzle is a split isobaric cutting nozzle.

[0015] In some embodiments, both the cutting assembly and the piercing assembly include an adjustable nozzle holder, through which the cutting nozzle and the piercing nozzle are positioned and installed.

[0016] According to another aspect of this application, a pre-filled syringe processing apparatus is provided, comprising: a pre-filled syringe forming apparatus and the pre-filled syringe flame processing apparatus as described above.

[0017] This application discloses a flame processing device for pre-filled syringes, comprising a cutting assembly and a piercing assembly. The cutting assembly includes a cutting nozzle that sprays multiple parallel flames, positioned before the separation station of the pre-filled syringe forming equipment and aligned with the portion of the glass tube to be cut. The piercing assembly includes a piercing nozzle that sprays a single flame, positioned after the separation station of the pre-filled syringe forming equipment and aligned with the two ends of the glass tube sealed after being flame-cut. Both the cutting nozzle and the piercing nozzle are connected to an external hydrogen gas source. This application utilizes flame cutting to divide the glass tube using the cutting assembly, and then pierces both ends of the glass tube using the piercing assembly for subsequent installation of needles, pistons, and other structures. The cutting process causes no mechanical vibration to the glass tube, resulting in high-quality cutting, uniform material distribution, and no gaps. Furthermore, the nozzles do not experience wear, eliminating the need for downtime for adjustment and maintenance. The cutting quality is stable and efficient, improving the cutting quality and production efficiency of pre-filled syringes. Simultaneously, this application uses hydrogen as the cutting gas source, which is more environmentally friendly than natural gas or other fuels. Attached Figure Description

[0018] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with this application and, together with the description, serve to explain the principles of this application.

[0019] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 This diagram shows the positions of the processing station and the mechanical cutting blade in an existing pre-filled syringe molding equipment;

[0021] Figure 2 This diagram shows the installation position of the pre-filled syringe flame processing device in the pre-filled syringe forming equipment.

[0022] Figure 3 A schematic diagram of the cutting nozzle structure of the pre-filled syringe flame processing device of this application is shown;

[0023] Figure 4 This paper shows a front view of the blow-through nozzle of the pre-filled syringe flame processing apparatus of this application;

[0024] Figure 5 A top view of the blow-through nozzle of the pre-filled syringe flame processing apparatus of this application is shown.

[0025] The above figures include the following reference numerals:

[0026] 1. Cutting assembly; 11. Cutting nozzle; 111. Flame hole; 112. Gas supply interface; 2. Blow-through assembly; 21. Blow-through nozzle; 3. Mechanical cutting blade. Detailed Implementation

[0027] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0028] It should be noted that the following detailed descriptions are illustrative and intended to provide further explanation of this application. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application pertains.

[0029] For ease of description, spatial relative terms such as "above," "on top of," "on the upper surface of," "above," etc., are used herein to describe the spatial positional relationship of a device or feature as shown in the figures to other devices or features. It should be understood that spatial relative terms are intended to encompass different orientations in use or operation beyond the orientation of the device as described in the figures. For example, if the device in the figures were inverted, a device described as "above" or "on top of" other devices or structures would subsequently be positioned as "below" or "under" other devices or structures. Thus, the exemplary term "above" can include both "above" and "below." The device may also be positioned in other different ways, rotated 90 degrees, or in other orientations, and the spatial relative descriptions used herein will be interpreted accordingly.

[0030] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0031] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of this application described herein can be implemented, for example, in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0032] Refer to this application Figure 1 As shown, in existing pre-filled syringe molding equipment, the main body of the equipment may include two parts, left and right, each with multiple processing stations for glass tubes (see reference). Figure 1As shown in sections A and B, the left and right equipment have overlapping processing stations at adjacent locations to achieve process integration. Section A on the left includes processing stations A1-A16, and section B on the right includes processing stations B1-B10. Station B2 overlaps with station A6, forming a separation station. Before the separation station, section A uses a mechanical cutter 3 to cut the glass tube. Section B separates the cut glass tube at the separation station using methods such as clamping and lifting. However, the mechanical cutter 3 causes mechanical vibration to the glass tube during cutting, which can easily lead to poor cutting, resulting in gaps and uneven material distribution, affecting the size of the pre-filled syringe after glass tube forming. Furthermore, the mechanical cutter 3 wears quickly, requiring periodic machine stops to adjust the feed position. Failure to adjust in time will result in poor cutting, affecting the product quality of the pre-filled syringe.

[0033] This application proposes improvements to address the aforementioned issues by designing a flame processing device for pre-filled syringe molding equipment to overcome the problem of poor cutting by the mechanical cutting blade 3 affecting product quality.

[0034] like Figures 2 to 5 As shown, this application discloses a flame processing device for pre-filled syringes, comprising: a cutting assembly 1, which includes a cutting nozzle 11 that sprays multiple parallel flames, the cutting nozzle 11 being positioned before the separation station of the pre-filled syringe forming equipment and aligned with the portion of the glass tube to be cut; and a piercing assembly 2, which includes a piercing nozzle 21 that sprays a single flame, the piercing nozzle 21 being positioned after the separation station of the pre-filled syringe forming equipment and aligned with the two ends of the glass tube that will be sealed after being cut by the flame. Both the cutting nozzle 11 and the piercing nozzle 21 are connected to an external hydrogen gas source.

[0035] Through the above structural design, this application utilizes flame cutting instead of traditional mechanical cutting. The cutting component 1 divides the glass tube, and after division, the flame-cut ends of the glass tube are opened by the piercing component 2, allowing for subsequent installation of needles, pistons, and other structures to achieve the desired shape. During the cutting process, this application causes no mechanical vibration to the glass tube, resulting in high-quality cutting, uniform material distribution, and no gaps. Furthermore, the flame nozzle does not experience wear, eliminating the need for downtime for adjustment and maintenance. The cutting quality is stable and efficient, improving the cutting quality and production efficiency of the pre-filled syringe. Simultaneously, this application uses hydrogen as the cutting fuel source, which is more environmentally friendly than natural gas or other fuels.

[0036] In some embodiments of this application, such as Figure 2 As shown, multiple sets of cutting nozzles 11 are provided, arranged sequentially from front to back before the separation station of the pre-filled syringe molding equipment. These multiple sets of cutting nozzles 11 heat the same area of ​​the glass tube to be cut. By using multiple sets of cutting nozzles 11, the heating time of the glass tube can be extended to smooth the heating process, preventing the glass tube from breaking due to intense heating and ensuring smooth and high-quality cutting.

[0037] In some embodiments of this application, such as Figure 2 As shown, there are three sets of cutting nozzles 11. The three sets of cutting nozzles 11 are respectively arranged at the three work stations in front of the separation station (i.e., processing stations A3, A4 and A5). The flame height of the three cutting nozzles 11 is the same as that of the glass tube, and they are aimed at the same position of the glass tube to heat it, so as to realize the preheating, cutting and melting of the glass tube, realize sequential heating and cutting, and improve the cutting quality.

[0038] In some embodiments of this application, such as Figure 2 As shown, from front to back, the flame intensity of each cutting nozzle 11 increases progressively to achieve preheating, cutting, and melting of the glass tube, respectively. Specifically, this can be achieved by installing valves with different opening degrees on the gas supply lines of the cutting nozzle 11.

[0039] In some embodiments of this application, such as Figure 3 As shown, the cutting nozzle 11 consists of one or more parallel ten-hole nozzles. A flame hole 111 is provided at the top of each parallel ten-hole nozzle, and a gas inlet 112 is provided at the side and rear of each parallel ten-hole nozzle. The parallel ten-hole nozzle ensures uniform heating throughout the glass tube, resulting in consistent glass deformation, preventing the glass tube from cracking or deforming unevenly, and improving the cut quality of the glass tube.

[0040] In some embodiments of this application, the nozzle orifice 111 of the parallel ten-hole nozzle has a diameter of 0.3 mm, which has a small flame size to achieve precise cutting. At the same time, the small flame orifice 111 also facilitates the use of an ultra-thin parallel ten-hole nozzle to reduce the volume of the cutting assembly 1, save space, and facilitate structural layout.

[0041] In some embodiments of this application, such as Figure 2 As shown, the blow-through assembly 2 is provided with at least two blow-through nozzles 21. One of the two blow-through nozzles 21 is set vertically upward, aimed at the closed bottom of the glass tube, and blows upward to pierce the closed separation layer generated at the bottom of the glass tube after flame cutting; the other is set vertically downward, aimed at the closed top of the glass tube, and blows downward to pierce the closed separation layer generated at the top of the glass tube after flame cutting.

[0042] In some embodiments of this application, such as Figure 2 As shown, two blow-through nozzles 21 are respectively set at different stations after the separation station of the pre-filled syringe forming equipment to cooperate with different subsequent processing stations to achieve syringe forming. For example, a downward blow-through nozzle 21 is set at station B4 of the equipment in section B, which blows downward to break through the closed top of the glass tube and cooperates with the subsequent needle mounting station; an upward blow-through nozzle 21 is set at station A9 of the equipment in section A, which blows upward to break through the closed bottom of the glass tube and cooperates with the subsequent piston mounting station.

[0043] In some embodiments of this application, such as Figure 4 and Figure 5 As shown, the blow-through nozzle 21 is a split-type isobaric cutter. Isobaric cutters have advantages such as long service life, high efficiency, and reliable safety. The split-type structure also facilitates cleaning and use by workers. The split-type isobaric cutter includes a cutter body, a mixer, a cutter outer sleeve, and a cutter inner nozzle, etc., with preheating oxygen holes, cutting oxygen holes, and cutting fuel gas holes on the front (e.g., Figure 5 (As shown). The blow-through nozzle 21 can directly use commercially available standard cutting nozzles, such as those conforming to national standards G01-G03, etc., the structure of which will not be described in detail here.

[0044] In some embodiments of this application, both the cutting assembly 1 and the blow-through assembly 2 further include an adjustable nozzle holder. The cutting nozzle 11 and the blow-through nozzle 21 are positioned and installed through the nozzle holder, and their positions can be adjusted through the nozzle holder to adapt to different batches of products and produce pre-filled syringes of different specifications.

[0045] According to another aspect of this application, a pre-filled syringe processing device is also disclosed. This device includes a pre-filled syringe forming device and a pre-filled syringe flame processing apparatus as shown in any of the above embodiments. This application improves cutting quality by replacing traditional mechanical cutting with flame cutting, resulting in flush cuts and uniform material distribution in the glass tubes, thus increasing the dimensional compliance rate of the pre-filled syringes. Furthermore, since the flame-jet processing method eliminates contact wear, frequent downtime for adjustments is unnecessary, reducing downtime probability, increasing continuous operation time, and improving the production efficiency of pre-filled syringes. Additionally, this application uses hydrogen energy as the cutting energy source, making it more environmentally friendly.

[0046] In summary, the pre-filled syringe flame processing device of this application includes a cutting component 1 and a blow-through component 2. The cutting component 1 includes a cutting nozzle 11 that sprays multiple parallel flames. The cutting nozzle 11 is set before the separation station of the pre-filled syringe forming equipment and is aimed at the part of the glass tube to be cut. The blow-through component 2 includes a blow-through nozzle 21 that sprays a single flame. The blow-through nozzle 21 is set after the separation station of the pre-filled syringe forming equipment and is aimed at the two ends of the glass tube that are sealed after being cut by the flame. Both the cutting nozzle 11 and the blow-through nozzle 21 are connected to an external hydrogen gas source. This application utilizes a flame cutting method to divide a glass tube using a cutting component 1. After division, the two ends of the glass tube are opened by a blow-through component 2 for subsequent installation of needles, pistons, and other structural components. During the cutting process, there is no mechanical vibration on the glass tube, resulting in high cutting quality, uniform material distribution, and no gaps. Furthermore, the flame nozzle does not experience wear, eliminating the need for machine downtime for adjustment and maintenance. The cutting quality is stable and efficient, improving the cutting quality and production efficiency of pre-filled syringes. Simultaneously, this application uses hydrogen as the cutting fuel source, which is more environmentally friendly compared to natural gas and other fuels.

[0047] The above are merely preferred embodiments of this application and are not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A flame processing device for pre-filled syringes, characterized in that, include: The cutting assembly (1) includes a cutting nozzle (11) that sprays multiple parallel flames. The cutting nozzle (11) is set before the separation station of the pre-filled syringe forming equipment and is aimed at the part of the glass tube to be cut. The blow-through assembly (2) includes a blow-through nozzle (21) that sprays a single beam of flame. The blow-through nozzle (21) is located after the separation station of the pre-filled syringe molding equipment and is aligned with the two ends of the glass tube that are sealed after being cut by the flame. Both the cutting nozzle (11) and the blowing nozzle (21) are connected to an external hydrogen gas source.

2. The flame processing device for pre-filled syringes according to claim 1, characterized in that, The cutting nozzle (11) is provided in multiple sets. The multiple sets of cutting nozzles (11) are arranged sequentially from front to back in front of the separation station of the pre-filled syringe forming equipment. The multiple sets of cutting nozzles (11) together heat the same part of the glass tube to be cut.

3. The flame processing device for pre-filled syringes according to claim 2, characterized in that, From front to back, the flame intensity of each of the cutting nozzles (11) increases progressively.

4. The flame processing device for pre-filled syringes according to claim 2, characterized in that, The cutting nozzle (11) consists of one or more parallel ten-hole nozzles, with a flame hole (111) at the top of the parallel ten-hole nozzle and a gas supply port (112) at the side and rear of the parallel ten-hole nozzle.

5. The flame processing apparatus for pre-filled syringes according to claim 4, characterized in that, The diameter of the flame hole (111) of the parallel ten-hole nozzle is 0.3 mm.

6. The flame processing device for pre-filled syringes according to claim 1, characterized in that, The blow-through assembly (2) is provided with at least two blow-through nozzles (21), one of which is set vertically upward and aligned with the closed bottom of the glass tube, and the other is set vertically downward and aligned with the closed top of the glass tube.

7. The flame processing apparatus for pre-filled syringes according to claim 6, characterized in that, The two blow-through nozzles (21) are respectively located at different stations behind the separation station of the pre-filled syringe molding equipment.

8. The flame processing apparatus for pre-filled syringes according to claim 6, characterized in that, The blow-through nozzle (21) is a split-type equal pressure cutting nozzle.

9. The flame processing device for pre-filled syringes according to claim 1, characterized in that, Both the cutting assembly (1) and the blow-through assembly (2) include an adjustable nozzle holder, and the cutting nozzle (11) and the blow-through nozzle (21) are positioned and installed through the nozzle holder.

10. A pre-filled syringe processing device, characterized in that, include: The pre-filled syringe forming equipment and the pre-filled syringe flame processing apparatus as described in any one of claims 1 to 9.

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