A high throughput screening device
By introducing a magnetic stirring device and quick-release assembly into the high-throughput screening device, uniform force connection between the top plate and the orifice plate is achieved, solving the sealing problem caused by top plate warping, improving sealing performance and ease of disassembly, and preventing sample leakage.
Patent Information
- Application Number
- CN202521105950.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-31
- Publication Date
- 2026-08-25
- Estimated Expiration
- 2035-05-31
AI Technical Summary
In existing high-throughput screening devices, the top and bottom plates are prone to warping due to uneven stress during the driving process, which affects the sealing performance and may lead to leakage of fermentation products and cross-contamination of samples.
A magnetic stirring device is used, and a uniform force connection between the top plate and the orifice plate is achieved through the installation of a sleeve, a motor-driven lead screw, and a threaded sleeve. Quick-release components and guide slides are used to improve connection stability and ease of disassembly, ensuring sealing.
It improves the sealing between the top plate, bottom plate, and orifice plate, preventing sample leakage and simplifying the disassembly and maintenance process of the device.
Smart Images

Figure CN224678026U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of screening device technology, and in particular to a high-throughput screening device. Background Technology
[0002] High throughput refers to the ability to process a large number of samples, data or complete a large number of tasks in a short period of time. It is widely used in scientific research, industry, medical and other fields. Its core characteristics are automation, scalability and high efficiency. Through technological innovation and process optimization, it breaks through the efficiency bottleneck of traditional methods.
[0003] Chinese Patent CN222715345U, authorized publication number, discloses a high-throughput yeast screening device, including a perforated plate body. A bottom plate is located below the perforated plate body, and a top plate is located above the perforated plate body. Screening chambers are evenly distributed on the perforated plate body. A fitting groove is formed at the bottom end of the outer wall of each screening chamber. Fitting frames are evenly installed on the top end of the bottom plate, inserted into the fitting groove. The fitting frames are U-shaped, with their outer walls tightly attached to the inner walls of the fitting grooves, and their inner sidewalls flush with the inner sidewalls of the screening chambers. In operation, the perforated plate body has evenly distributed screening chambers, and the fitting grooves are formed at the bottom of the inner walls of the screening chambers. The U-shaped fitting frames are evenly installed on the top end of the bottom plate, allowing them to be embedded into the fitting grooves. The cooperation between the fitting grooves and the fitting frames prevents fermentation material from entering other screening chambers through the gap between the perforated plate body and the bottom plate, thus facilitating fermentation.
[0004] However, the above-mentioned technical solution still has the following shortcomings in actual use. In order to allow the top plate and bottom plate to move up and down, and for the two insert plates to press the bottom plate and top plate against the perforated plate body, the insert plates are located in the middle of the sides of the bottom plate and top plate. When the two sets of insert plates drive the bottom plate and top plate to fit together, the force is easily applied to the sides of the bottom plate and top plate. This uneven force distribution can easily cause the front and rear sides of the bottom plate and top plate to warp, thereby damaging the sealing of the screening chamber on the perforated plate body, which may lead to fermentation product leakage and sample cross-contamination. Therefore, we propose a high-throughput screening device to solve the above problems. Utility Model Content
[0005] The purpose of this invention is to provide a high-throughput screening device to solve the problems mentioned in the background art.
[0006] To achieve the above objectives, this utility model provides the following technical solution: a high-throughput screening device, comprising a magnetic stirring device, wherein the magnetic stirring device is provided with a perforated plate body, a bottom plate, and a top plate; two sets of side sleeves are installed on both sides of the perforated plate body, the bottom plate, and the top plate; transverse connecting rods are provided on both sides of the perforated plate body and the top plate; both sides of the two sets of transverse connecting rods are connected to the side sleeves outside the perforated plate body and the top plate via quick-release components; two sets of guide slide rods are installed on both sides of the top of the magnetic stirring device; the side sleeves are all fitted over the guide slide rods; the top of the magnetic stirring device... Both sides are equipped with sleeves, and a first lead screw and a second lead screw are rotatably connected inside the sleeves. The first lead screw and the second lead screw are respectively connected to a first threaded sleeve and a second threaded sleeve. A first motor and a second motor are installed at the top of the sleeves. The output ends of the first motor and the second motor are respectively connected to the top of the first lead screw and the second lead screw. Two sets of guide grooves are opened at opposite ends of the two sets of sleeves. The first threaded sleeve and the second threaded sleeve are respectively connected to the horizontal connecting rod outside the top plate and the perforated plate through connecting brackets. The connecting brackets all pass through the inside of the guide grooves.
[0007] As an improved technical solution, the quick-release assembly includes sliding grooves on both sides of the front end of the cross link, each sliding groove being slidably connected to a slider. Each of the two sets of sliders on the sliding groove has a plug rod fixed at one end facing away from the other. Each side sleeve has a plug hole, and the end of each plug rod can be inserted into the plug hole. Each of the two sets of sliders has a return spring at one end facing away from the other, and a lever is installed at the end of each slider away from the top plate.
[0008] As an improved technical solution, each guide slide rod is provided with a positioning bolt at its top end, and the top end of the guide slide rod is provided with a threaded hole that matches the positioning bolt. The guide slide rod is threadedly connected to the positioning bolt.
[0009] As an improved technical solution, the input ends of the second motor and the guide slide are both electrically connected to an external controller via wires.
[0010] As an improved technical solution, the outer wall of the connecting bracket is fully fitted with the inner wall of the guide groove on the sleeve, and the connecting bracket and the guide groove form a sliding connection.
[0011] As an improved technical solution, the outer wall of the insertion rod is fully fitted with the inner wall of the insertion hole on the side sleeve.
[0012] As an improved technical solution, the surface of the dial plate is provided with anti-slip texture.
[0013] After adopting the above technical solution, the beneficial effects of this utility model are: I. This utility model features sleeves installed on both sides of the top of a magnetic stirring device, with a first motor and a second motor mounted on the top of the sleeves. The first and second motors drive the first lead screw and the second threaded sleeve to rotate, thereby moving the first threaded sleeve and the second threaded sleeve along the axial direction of the lead screw. This causes the first and second threaded sleeves to lift and lower two sets of horizontal connecting rods, which in turn adjust the vertical position of the side sleeves on the top plate and the perforated plate body. This ensures that the two sets of side sleeves are evenly stressed on both sides of the top plate and the perforated plate body, thus ensuring that the top plate, the perforated plate body, and the bottom plate can fit tightly together. This improves the tightness of the connection and effectively avoids warping caused by single-point force application. It also significantly improves the sealing between the top plate, the bottom plate, and the perforated plate body, preventing sample leakage.
[0014] II. This utility model features a movable slider mounted on the cross link. A lever can be moved to compress the return spring of the slider, allowing the slider to quickly pull the insertion rod out of the insertion hole on the side sleeve. This allows the cross link to quickly disconnect from the top plate and the perforated plate body, facilitating the disassembly of the top plate and the perforated plate body. It also facilitates the lifting of the top plate / perforated plate body and the bottom plate from the two sets of guide slides, making it easier to clean and maintain the inside of the perforated plate body. Attached Figure Description
[0015] Figure 1 This is a three-dimensional structural diagram of the present invention; Figure 2 This is a partial cross-sectional structural diagram of the present invention; Figure 3 For the present utility model Figure 2 A magnified structural diagram at point A; Figure 4 For the present utility model Figure 2 A magnified structural diagram at point B.
[0016] In the diagram: 1. Magnetic stirring device; 2. Orifice plate body; 3. Bottom plate; 4. Top plate; 5. Side sleeve; 6. Horizontal connecting rod; 7. Sleeve seat; 8. First lead screw; 9. Second lead screw; 10. First threaded sleeve; 11. Second threaded sleeve; 12. Connecting bracket; 13. First motor; 14. Second motor; 15. Guide slide rod; 16. Positioning bolt; 17. Slide groove; 18. Slider; 19. Insert rod; 20. Insertion hole; 21. Pulley; 22. Return spring; 23. Guide groove. Detailed Implementation
[0017] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings.
[0018] This utility model provides a technical solution: such as Figures 1 to 4As shown, in this embodiment, a high-throughput screening device includes a magnetic stirring device 1. The magnetic stirring device 1 is equipped with a perforated plate body 2, a bottom plate 3, and a top plate 4. Two sets of side sleeves 5 are installed on both sides of the perforated plate body 2, bottom plate 3, and top plate 4. Horizontal connecting rods 6 are provided on both sides of the perforated plate body 2 and top plate 4. Both sides of the two sets of horizontal connecting rods 6 are connected to the side sleeves 5 outside the perforated plate body 2 and top plate 4 via quick-release components. Two sets of guide slide rods 15 are installed on both sides of the top of the magnetic stirring device 1, and the side sleeves 5 are fitted over the guide slide rods 15. Sleeve seats 7 are installed on both sides of the top of the magnetic stirring device 1. The inner rotating connection includes a first lead screw 8 and a second lead screw 9. The first lead screw 8 and the second lead screw 9 are respectively connected to the first threaded sleeve 10 and the second threaded sleeve 11. The top of the sleeve 7 is equipped with a first motor 13 and a second motor 14. The output ends of the first motor 13 and the second motor 14 are respectively connected to the top of the first lead screw 8 and the second lead screw 9. The two sets of sleeves 7 have two sets of guide grooves 23 at opposite ends. The first threaded sleeve 10 and the second threaded sleeve 11 are both connected to the horizontal connecting rod 6 on the outside of the top plate 4 and the perforated plate 2 through the connecting bracket 12. The connecting bracket 12 passes through the inside of the guide groove 23.
[0019] By installing sleeves 7 on both sides of the top of the magnetic stirring device 1, and installing a first motor 13 and a second motor 14 on the top of the sleeves 7, the first motor 13 and the second motor 14 drive the first lead screw 8 and the second lead screw 9 to rotate, thereby driving the first threaded sleeve 10 and the second threaded sleeve 11 to move along the lead screw axis. This allows the first threaded sleeve 10 and the second threaded sleeve 11 to drive the two sets of horizontal connecting rods 6 to rise and fall. The two sets of horizontal connecting rods 6 then adjust the vertical position of the side sleeves 5 outside the top plate 4 and the perforated plate body 2, ensuring that the top plate 4 and the perforated plate body 2 are evenly stressed on both sides. This ensures that the top plate 4, the perforated plate body 2 and the bottom plate 3 can fit tightly together, improving the tightness of the connection and effectively avoiding the warping problem caused by single-point force application. It also significantly improves the sealing between the top plate 4, the bottom plate 3 and the perforated plate body 2, preventing sample leakage.
[0020] In other embodiments, the quick-release assembly includes slide grooves 17 on both sides of the front end of the cross link 6. Each slide groove 17 is slidably connected to a slider 18. Each of the two sets of sliders 18 on the slide groove 17 has a plug rod 19 fixed at one of their opposite ends. Each side sleeve 5 has a plug hole 20. The end of each plug rod 19 can be inserted into the plug hole 20. Each of the two sets of sliders 18 has a return spring 22 at one of their opposite ends. Each slider 18 has a lever plate 21 installed at the end away from the top plate 4. By installing a movable slider 18 on the cross link 6, the lever 21 can be turned to compress the return spring 22, allowing the slider 18 to quickly withdraw the insertion rod 19 from the insertion hole 20 on the side sleeve 5. This allows the cross link 6 to quickly disconnect from the top plate 4 and the perforated plate 2, facilitating the disassembly of the top plate 4 and the perforated plate 2. When the lever 21 is released, the return spring 22 releases its elastic force to push the insertion rod 19 back into the insertion hole 20 on the side sleeve 5, completing the connection between the top plate 4, the perforated plate 2, and the cross link 6.
[0021] In other embodiments, a positioning bolt 16 is provided at the top of the guide slide rod 15, and a screw hole matching the positioning bolt 16 is opened at the top of the guide slide rod 15, and the guide slide rod 15 is threadedly connected to the positioning bolt 16. This design facilitates the quick installation and removal of the positioning bolt 16 at the top of the guide slide rod 15, allowing the positioning bolt 16 to limit the top of the guide slide rod 15 and prevent the side sleeve 5 on the top plate 4 from leaving the guide slide rod 15.
[0022] In other embodiments, the input ends of the second motor 14 and the guide slide 15 are both electrically connected to an external controller via wires; This design allows an external controller to control the start and stop of the second motor 14 and the guide slide 15 in real time, enabling the second motor 14 and the guide slide 15 to start in staggered order.
[0023] In other embodiments, the outer wall of the connecting bracket 12 is fully fitted with the inner wall of the guide groove 23 on the sleeve 7, and the connecting bracket 12 and the guide groove 23 form a sliding connection. This design prevents the connecting bracket 12 from shaking during movement when the first threaded sleeve 10 or the second threaded sleeve 11 drives the connecting bracket 12 to move up and down along the inside of the guide groove 23.
[0024] In other embodiments, the outer wall of the insertion rod 19 is fully fitted with the inner wall of the insertion hole 20 on the side sleeve 5; With this design, when the end of the insertion rod 19 is inserted into the insertion hole 20, the cross link 6 can form a stable connection with the side sleeve 5 through the insertion rod 19, thereby improving the stability of the equipment connection.
[0025] In other embodiments, the surface of the dial 21 is provided with anti-slip texture; This design effectively increases the friction between the dial 21 and the user's hand, making it easier to move the dial 21 effectively.
[0026] The electrical components mentioned in this article are all electrically connected to an external main controller and industrial power supply, and the main controller can be a conventional known device such as a computer that provides control.
[0027] It should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solution of this utility model without departing from the spirit and scope of the technical solution of this utility model, and all such modifications or substitutions should be covered within the scope of the claims of this utility model.
Claims
1. A high-throughput screening device, comprising a magnetic stirring device (1), wherein the magnetic stirring device (1) is provided with a perforated plate body (2), a bottom plate (3) and a top plate (4), characterized in that: Two sets of side sleeves (5) are installed on both sides of the perforated plate body (2), bottom plate (3), and top plate (4). A horizontal connecting rod (6) is provided on both sides of the perforated plate body (2) and top plate (4). Both sets of horizontal connecting rods (6) are connected to the side sleeves (5) outside the perforated plate body (2) and top plate (4) via quick-release components. Two sets of guide slide rods (15) are installed on both sides of the top of the magnetic stirring device (1). The side sleeves (5) are fitted onto the outside of the guide slide rods (15). A sleeve seat (7) is installed on both sides of the top of the magnetic stirring device (1). A first lead screw (8) and a second lead screw (9) are rotatably connected inside the sleeve seat (7). The first lead screw (8)... The first threaded sleeve (10) and the second threaded sleeve (11) are respectively connected to the outside of the second lead screw (9). The first motor (13) and the second motor (14) are installed on the top of the sleeve (7). The output ends of the first motor (13) and the second motor (14) are respectively connected to the top of the first lead screw (8) and the second lead screw (9). Two sets of guide grooves (23) are opened at opposite ends of the two sets of sleeves (7). The first threaded sleeve (10) and the second threaded sleeve (11) are respectively connected to the horizontal connecting rod (6) outside the top plate (4) and the perforated plate (2) through the connecting bracket (12). The connecting bracket (12) passes through the inside of the guide groove (23).
2. The high-throughput screening device according to claim 1, characterized in that: The quick-release assembly includes sliding grooves (17) on both sides of the front end of the cross link (6). Each sliding groove (17) is slidably connected to a slider (18). Each of the two sets of sliders (18) on the sliding groove (17) has a plug rod (19) fixed at one end opposite to the other. Each side sleeve (5) has a socket (20) for inserting the end of the plug rod (19) into the socket (20). Each of the two sets of sliders (18) has a return spring (22) at one end opposite to the other. Each slider (18) has a lever (21) installed at the end away from the top plate (4).
3. The high-throughput screening device according to claim 1, characterized in that: The top of each guide slide rod (15) is provided with a positioning bolt (16), and the top of the guide slide rod (15) is provided with a screw hole that matches the positioning bolt (16). The guide slide rod (15) and the positioning bolt (16) are threadedly connected.
4. The high-throughput screening device according to claim 1, characterized in that: The input ends of the second motor (14) and the guide slide (15) are electrically connected to an external controller via wires.
5. A high-throughput screening device according to claim 1, characterized in that: The outer wall of the connecting bracket (12) is fully fitted with the inner wall of the guide groove (23) on the sleeve (7), and the connecting bracket (12) and the guide groove (23) form a sliding connection.
6. A high-throughput screening device according to claim 2, characterized in that: The outer wall of the insertion rod (19) is fully fitted with the inner wall of the insertion hole (20) on the side sleeve (5).
7. A high-throughput screening device according to claim 2, characterized in that: The surface of the dial (21) is provided with anti-slip texture.
Citation Information
Patent Citations
Yeast high-throughput screening device
CN222715345U