Sample preparation cartridge with upward protrusion

Abstract

The sample preparation box with upward protruding part comprises a sampling spoon, a containing part and a cover part; the sampling spoon comprises a rotating part and a spoon part; the rotating part is fixedly connected with the spoon part; the cover part comprises a rotating connecting part; the rotating part is connected with the rotating connecting part; the containing part comprises an A cavity and a B cavity; a filter partition is arranged between the A cavity and the B cavity; in a closed state, the cover part covers an opening part of the A cavity, and the spoon part is in the A cavity; the bottom of the A cavity comprises an upward protruding part, and the top of the upward protruding part enters a rotating space of the sampling spoon. A center column is arranged at the rotating center position of the spoon, so as to force the feces to separate from the bottom of the spoon, and at the same time, the center column drives water flow to impact the bottom of the spoon during the rotation, so that the feces on the bottom of the spoon is quickly disintegrated and enters a rotating and crushing state.

Description

Technical Field

[0001] This application belongs to the field of detection and analysis technology, and specifically relates to reagent kits and carrier devices used in the field of automated detection. Background Technology

[0002] Before biological samples can be tested and analyzed, they need to undergo processing procedures corresponding to the specific testing requirements, followed by the detection of the underlying principles. Different testing principles necessitate different pre-treatment requirements and procedures for samples. Raw samples typically require specialized operations such as dilution, staining, centrifugation, and concentration. These preparation operations usually require testing personnel to follow standardized procedures. However, human operational capabilities and precision are limited, and many intricate operations gradually exceed the limits of human ability. This is especially true in veterinary hospitals, where there are many different types of animals and an increasing number of testing requirements. However, due to cost constraints and limited personnel, many testing procedures are difficult to conduct in veterinary hospitals.

[0003] Therefore, both human and veterinary hospitals need to fully automate the testing process, minimizing the steps that require human intervention.

[0004] In fecal testing, sample preparation is automated, leading to the development of sampling preparation kits that combine sample collection and mixing. However, these kits have several problems in practical use. For instance, during the rotation of the spoon, feces adhere to the bottom, hindering effective mixing. Summary of the Invention

[0005] In this application, to prevent feces from sticking to the bottom of the spoon during the stirring process and causing the stirring to fail to be completed effectively, the applicant proposes to set a central column at the center of the spoon's rotation to force the feces to detach from the bottom of the spoon. At the same time, during the rotation, the central column drives water flow to impact the bottom of the spoon, causing the feces at the bottom of the spoon to quickly disintegrate and enter a rotating pulverizing state.

[0006] The technical solution of this application to solve the above-mentioned technical problems is a sample preparation box with an upward protrusion, including: a sampling spoon, a receiving part, and a cover; the sampling spoon includes a rotating part and a spoon part; the rotating part and the spoon part are fixedly connected; the cover includes a rotating connecting part; the rotating part and the rotating connecting part are connected; the receiving part includes cavity A and cavity B; a filter partition is provided between cavity A and cavity B; in the closed state, the cover covers the opening of cavity A, and the spoon part is in cavity A; the bottom of cavity A includes an upward protrusion, and the top of the upward protrusion enters the rotating space of the sampling spoon.

[0007] Yes, the upward-protruding part can be columnar.

[0008] It is possible that the center of the upward protrusion is offset from the rotation center of the sampling spoon.

[0009] It is possible that the cross-section of the upward-protruding part is paddle-shaped.

[0010] It could be that the cross-section of the upward-protruding part is fish-shaped, with the center of the fish head at the center of rotation.

[0011] It is possible that the height of the upward-protruding part is less than the height of the base of the spoon.

[0012] Yes, the columnar object has fins on its exterior.

[0013] It is possible that the bottom of part of cavity A and part of cavity B are on a continuous inclined surface, with the lowest point of the inclined surface at the bottom of cavity B, and the upward protrusion is set on the inclined surface.

[0014] It can be that the filter baffle includes an inclined portion that is inclined toward cavity B, and the inclined portion expands the opening area of ​​cavity A; the cover also includes a liquid filling hole; in the closed state, the liquid filling hole is used to add reagents, dyes or diluents to cavity A.

[0015] It could be that the cross-section of the spoon is an arc; the curvature of the cross-section of the main body of the spoon is greater than 180 degrees; and the top of the spoon covers the lower body of the spoon.

[0016] One of the technical effects of the above-mentioned solution is that the bottom of cavity A includes an upwardly protruding portion. This upward protrusion is used to push apart solid substances in the sample, thereby achieving dispersion and preventing the sample from agglomerating at the bottom center. When solid substances in a normal fecal sample clump together, only rotation can cause the entire clump to rotate, further agglomerating the sample. After the suspension rotates, it will concentrate and gather at the bottom. This structure can prevent agglomeration at the bottom center.

[0017] One of the technical effects of the above-mentioned technical solution is that the upper protrusion is columnar, which forces the feces to detach from the bottom of the spoon during the insertion of the sampling spoon.

[0018] One of the technical effects of the above-mentioned technical solution is that the protruding parts around the upper convex part make it easier to scrape the feces away from the bottom of the spoon.

[0019] One of the technical effects of the above-mentioned technical solution is that the upper protrusion is a columnar object. During the rotation process, the columnar object drives the water flow to impact the bottom of the spoon, causing the feces at the bottom of the spoon to quickly disintegrate and enter the rotating pulverizing state.

[0020] One of the technical effects of the above-mentioned technical solution is that the center of the upward protrusion is offset from the rotation center of the sampling spoon, which can prevent the sample from gathering at the center position.

[0021] One of the technical effects of the above-mentioned technical solution is that the cross-section of the upper protrusion is paddle-shaped, which is beneficial for dispersing the sample during rotation.

[0022] One of the technical effects of the above-mentioned technical solution is that the cross-section of the upper protrusion is fish-shaped, with the center of the fish head at the center of rotation and a narrow space formed at the tail, which makes the cross-section of the flow channel at the edge relatively small, making it easy to form a flow velocity difference, which is beneficial to the dispersion of solid samples.

[0023] One of the technical effects of the above-mentioned technical solution is that the height of the upper protrusion is less than the height of the base of the spoon, which can ensure that the two work together more efficiently within the space of the sampling spoon.

[0024] One of the technical effects of the above-mentioned technical solution is that the fins on the outside of the column help to disperse the sample during rotation.

[0025] One of the technical effects of the above-mentioned technical solution is that the upward protrusion is set on the inclined surface, which is conducive to the sample being dispersed and enriched into cavity B at the same time.

[0026] One of the technical effects of the above-mentioned technical solution is that the inclined part increases the opening area of ​​cavity A, which is beneficial for sample addition and dispersion; the liquid addition hole facilitates the addition of various liquids or intermediate reagents, making it convenient to use.

[0027] One of the technical effects of the above-mentioned technical solution is that the cross-section of the spoon is an arc with a curvature greater than 180 degrees, which helps to confine the upper protrusion within the space of the spoon and enhance the dispersion effect; the top of the spoon covers the lower main body of the spoon, further restricting the sample space and enhancing the dispersion effect. Attached Figure Description

[0028] Figure 1 This is a schematic diagram of a perspective view of Embodiment 1; Figure 2 This is a schematic diagram of an exploded view of Embodiment 1; Figure 3 This is a schematic diagram of a partial exploded view of Embodiment 1; Figure 4 This is a schematic diagram of the dissection of Example 1; Figure 5 This is a schematic diagram of the horizontal cross-section of the columnar object and the rotating spoon. Figure 1 ; Figure 6 This is a schematic diagram of the horizontal cross-section of the columnar object and the rotating spoon. Figure 2 ; Figure 7 This is a schematic diagram of the horizontal cross-section of the columnar object and the rotating spoon. Figure 3 ; Figure 8 This is a schematic diagram of a top perspective view of the receiving part in Embodiment 2; Figure 9 This is a schematic diagram of an exploded view of Example 3; Figure 10This is a schematic diagram of a perspective view of Embodiment 3; Figure 11 This is a schematic diagram of the centerline cross-sectional view of Example 3. Detailed Implementation

[0029] The content of this application will be further described in detail below with reference to the accompanying drawings. It should be noted that the following description is of preferred embodiments of this application and does not constitute any limitation on this application. The description of the preferred embodiments is merely an explanation of the general principles of this application. The use of terms such as "first," "second," and "A," "B" in this application is for ease of explanation only and does not represent a temporal or spatial order. The combinations of letters and numbers "S," "M," and "H" in this application are also for ease of explanation, and their specific meanings are determined by the specific content they refer to.

[0030] like Figure 1 The perspective view of Embodiment 1 includes: a sampling spoon, a receiving part 0110, and a cover part 0120.

[0031] like Figure 2 An exploded view of Embodiment 1; the sampling spoon 0210 includes a rotating part 0211 and a spoon part 0212; the rotating part and the spoon part are fixedly connected; the cover part 0120 includes a rotating connecting part 0230; the rotating part 0211 is connected to the rotating connecting part 0230. In the closed state, the cover part covers the opening of cavity A, and the spoon part is in cavity A.

[0032] like Figure 3 Partial exploded view of Embodiment 1; the receiving part includes cavity A 0310 and cavity B 0320; a filter partition 0330 is provided between cavity A and cavity B; the receiving part includes a groove 0350, and the filter partition 0330 is inserted into the groove 0350.

[0033] like Figure 3 The filter baffle includes an inclined portion 0331, which is inclined toward cavity B, thereby increasing the opening area of ​​cavity A.

[0034] like Figure 2 The cover also includes a liquid filling hole 0231; in the closed state, the liquid filling hole is used to add reagents, dyes or diluents to cavity A.

[0035] like Figure 4 The bottom of cavity A 0310 includes an upward protrusion, the top of which leads into the rotation space of the sampling spoon. This upward protrusion is a columnar part 0410.

[0036] like Figure 5A schematic diagram of a horizontal cross-section of a columnar object and a rotating spoon; the center 0510 of the upward protrusion is offset from the rotation center 0521 of the sampling spoon 0520. During the rotation of the sampling spoon, the eccentric setting of the upward protrusion causes the impact pressure to change continuously, forcing the feces to detach from the spoon.

[0037] like Figure 6 A schematic diagram of a horizontal cross-section of a columnar object and a rotating spoon; the cross-section of the upwardly protruding part is paddle-shaped (0610), and the cross-section of the sampling spoon is (0620). The paddle-shaped edge forces the feces out of the spoon during rotation.

[0038] like Figure 7 A schematic diagram of a horizontal cross-section of a columnar object and a rotating spoon; the cross-section of the upwardly protruding part is fish-shaped 0710, and the cross-section of the sampling spoon is 0720; the center of the fish head is at the center of rotation. The fish shape can be one end large and one end small, with the small end biased towards the direction of rotation. With this shape, feces are less likely to get stuck at the tail.

[0039] like Figure 4 The height of the upward-protruding part is less than the height of the base of the spoon. When the spoon is inserted, the bottom of the spoon does not contact the upward-protruding part. like Figure 8 The schematic diagram of the top perspective of the receiving part in Embodiment 2 shows that the columnar object is provided with fins 0810.

[0040] like Figure 10 A schematic diagram of a three-dimensional view of Example 3; as shown Figure 9 A schematic diagram of the exploded view of Embodiment 3; Embodiment 3 includes: a sampling spoon 0910, a receiving part 0920, and a cover part 0930; a filter partition 0953 is provided between cavity A 0951 and cavity B 0952.

[0041] like Figure 11 A schematic diagram of the centerline cross-section of Embodiment 3; the bottom portions of cavity A 0951 and cavity B 0952 are on a continuous inclined surface 1110, with the lowest point 1111 of the inclined surface at the bottom of cavity B. A columnar object 1150 is disposed on the continuous inclined surface 1110.

[0042] like Figure 11 It also includes cavity C 1130, which is used to place the absorbent block; cavity C is located on the other side of cavity B away from cavity A.

[0043] like Figure 9 The cross-section of the spoon part is an arc 0911; the cross-section of the main body of the spoon part has an arc greater than 180 degrees; the top of the spoon 0912 covers the lower main body of the spoon part.

[0044] While this application has been described and illustrated with reference to preferred embodiments and several alternatives, it is not intended to be limited to the specific descriptions herein. Other alternatives or equivalent components may also be used to practice this application.

Claims

1. A sample preparation box with an upwardly protruding portion, characterized in that, include: Sampling spoon, receiving part, lid; The sampling spoon includes a rotating part and a spoon part; the rotating part and the spoon part are fixedly connected. The cover includes a rotatable connecting part; the rotatable part is connected to the rotatable connecting part; The receiving part includes cavity A and cavity B; a filter partition is provided between cavity A and cavity B; In the closed state, the cover covers the opening of cavity A, and the spoon is inside cavity A; The bottom of cavity A includes an upward protrusion, the top of which enters the rotation space of the sampling spoon.

2. The sample preparation box with an upwardly protruding portion according to claim 1, characterized in that, The upward protrusion is columnar.

3. The sample preparation box with an upwardly protruding portion according to claim 1, characterized in that, The center of the upward protrusion is offset from the rotation center of the sampling spoon.

4. The sample preparation box with an upwardly protruding portion according to claim 1, characterized in that, The cross-section of the upwardly protruding part is paddle-shaped.

5. The sample preparation box with an upwardly protruding portion according to claim 1, characterized in that, The cross-section of the upward protrusion is fish-shaped, with the center of the fish head at the center of rotation.

6. The sample preparation box with an upwardly protruding portion according to claim 1, characterized in that, The height of the upward protrusion is less than the height of the base of the spoon.

7. The sample preparation box with an upwardly protruding portion according to claim 2, characterized in that, The column is provided with fins on its exterior.

8. The sample preparation box with an upwardly protruding portion according to claim 2, characterized in that, The bottom of cavity A and part of cavity B are on a continuous inclined surface, with the lowest point of the inclined surface at the bottom of cavity B. The upward protrusion is provided on the inclined surface; the column is provided on the continuous inclined surface.

9. The sample preparation box with an upwardly protruding portion according to claim 1 or 4, characterized in that, The filter baffle includes an inclined portion that is inclined toward cavity B, thereby increasing the opening area of ​​cavity A; the cover also includes a liquid inlet; in the closed state, the liquid inlet is used to add reagents, dyes, or diluents to cavity A.

10. The sample preparation box with an upwardly protruding portion according to claim 1, characterized in that, The cross-section of the spoon part is an arc; the arc of the cross-section of the main body of the spoon part is greater than 180 degrees; the top of the spoon covers the lower body of the spoon part.

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