hematology analyzer

Abstract

The utility model provides a kind of blood cell analyzer, including sampling component, processing component, detection component and analysis component, sampling component includes sampling needle, sampling driving part, first pipeline, second pipeline, third pipeline, first switching structure, liquid discharge driving part and atmospheric communication part, wherein, the both ends of first pipeline are connected with sampling needle and first switching structure respectively, the both ends of second pipeline are connected with first switching structure and sampling driving part respectively, the both ends of third pipeline are connected with first switching structure and liquid discharge driving part respectively, atmospheric communication part can communicate third pipeline and atmosphere, first switching structure has first working state and second working state, so that sampling needle is inserted into closed test tube, closed test tube can be communicated with atmosphere by sampling needle, first pipeline and third pipeline and pressure relief when inserting sampling needle into closed test tube.The technical scheme of the application can effectively solve the problem of high cost and difficult to clean of the sampling needle in related technology.

Description

Technical Field

[0001] This utility model relates to the field of blood testing technology, and more specifically, to a blood cell analyzer. Background Technology

[0002] In related technologies, blood cell analyzers need to automatically puncture and draw blood samples from sealed test tubes for analysis and measurement. However, sealed test tubes often use vacuum blood collection tubes. After venous blood is collected, there will still be a certain residual negative pressure in the test tube, which will affect the accuracy of sampling.

[0003] To address these issues, some manufacturers incorporate two channels into their sampling needles: one for sampling and the other connecting to the atmosphere and a sealed test tube. This ensures the pressure inside the sealed test tube matches atmospheric pressure, improving sampling accuracy. However, this design increases the complexity of the sampling needle, leading to higher manufacturing costs and making cleaning the needle more difficult. Utility Model Content

[0004] The main objective of this invention is to provide a blood cell analyzer to solve the problems of high cost and difficulty in cleaning sampling needles in related technologies.

[0005] To achieve the above objectives, this utility model provides a blood cell analyzer, including a sampling component, a processing component, a detection component, and an analysis component. The sampling component includes a sampling needle, a sampling drive, a first tubing, a second tubing, a third tubing, a first switching structure, a draining drive, and an atmospheric connection. The first tubing is connected at both ends to the sampling needle and the first switching structure, the second tubing is connected at both ends to the first switching structure and the sampling drive, and the third tubing is connected at both ends to the first switching structure and the draining drive. The atmospheric connection is disposed on the third tubing or on the draining drive and connects the third tubing to the atmosphere. The switching structure has a first working state and a second working state. When the first switching structure is in the first working state, it connects the first and second pipelines and disconnects the third pipeline, so that the sampling needle and the sampling drive are connected. When the first switching structure is in the second working state, it connects the first and third pipelines and disconnects the second pipeline, so that the sampling needle and the draining drive are connected. The draining drive can drive the liquid in the sampling needle, the first pipeline and the third pipeline to be discharged, so that when the sampling needle is inserted into the closed test tube, the closed test tube can be depressurized by communicating with the atmosphere through the sampling needle, the first pipeline and the third pipeline.

[0006] Furthermore, the first switching structure includes a first three-way valve, which has a first valve port, a second valve port, and a third valve port. A first pipeline is connected to the first valve port, a second pipeline is connected to the second valve port, and a third pipeline is connected to the third valve port. When the first switching structure is in a first working state, the first valve port and the second valve port are connected, and the third valve port is disconnected from the first valve port and the second valve port. When the first switching structure is in a second working state, the first valve port and the third valve port are connected, and the second valve port is disconnected from the first valve port and the third valve port.

[0007] Furthermore, the first switching structure includes a first tee pipe joint, a first on / off valve, and a second on / off valve. The first tee pipe joint has a first interface, a second interface, and a third interface. The first pipeline is connected to the first interface. The first on / off valve is disposed between the second interface and the second pipeline. The second on / off valve is disposed between the third interface and the third pipeline.

[0008] Furthermore, the liquid discharge drive is a rotary air pump. When the rotary air pump is working, it pumps air into the third pipeline, the first pipeline, and the sampling needle so that the liquid in the sampling needle, the first pipeline, and the third pipeline is discharged from the sampling port of the sampling needle. The atmospheric communication device is the air inlet of the rotary air pump.

[0009] Furthermore, the sampling component also includes a second switching structure disposed on the third pipeline. The second switching structure divides the third pipeline into a first sub-pipeline close to the first switching structure and a second sub-pipeline disposed close to the drain drive. The second switching structure has a third working state and a fourth working state. When the second switching structure is in the third working state, the second switching structure connects the first sub-pipeline and the second sub-pipeline and disconnects the atmosphere. When the second switching structure is in the fourth working state, the second switching structure connects the first sub-pipeline and the atmosphere.

[0010] Furthermore, the second switching structure includes a second three-way valve, which has a fourth valve port, a fifth valve port, and a sixth valve port. A first sub-pipeline is connected to the fourth valve port, a second sub-pipeline is connected to the fifth valve port, and the sixth valve port is open to the atmosphere. When the second switching structure is in the third working state, the fourth and fifth valve ports are connected, and the sixth valve port is disconnected from the fourth and fifth valve ports. When the second switching structure is in the fourth working state, the fourth and sixth valve ports are connected. Alternatively, the second switching structure includes a second three-way pipe joint and a third on-off valve, which has a fourth interface, a fifth interface, and a sixth interface. A first sub-pipeline is connected to the fourth interface, a second sub-pipeline is connected to the fifth interface, and the sixth interface is connected to the third on-off valve.

[0011] Furthermore, the sampling port is located on the side wall of the sampling needle, and the sampling assembly also includes a cleaning swab sleeved on the sampling needle. The sampling needle and the cleaning swab slide together and have a drainage engagement state in which the cleaning swab is located outside the sampling port.

[0012] Furthermore, the drain drive is a positive pressure source or a negative pressure source, and the atmospheric connection is a fourth shut-off valve, which is installed on the third pipeline or on the drain drive.

[0013] Furthermore, an air filter is installed on the atmospheric connector.

[0014] Furthermore, the sampling drive has a top opening and a side opening. The top opening is connected to the second pipeline. The sampling assembly also includes a fourth pipeline, a liquid storage container, and a fifth on / off valve. The liquid storage container is used to store cleaning fluid. The fourth pipeline is connected between the side opening and the liquid storage container. The fifth on / off valve is located on the fourth pipeline.

[0015] By applying the technical solution of this utility model, before sampling, the first switching structure is controlled to be in the second working state, connecting the first and third pipelines. The liquid discharge drive drives the sampling needle, the liquid in the first and third pipelines to be discharged, and the atmospheric connection connects the third pipeline to the atmosphere. Then, the sampling needle is inserted into the closed test tube to be sampled. The closed test tube is connected to the atmosphere through the sampling needle, the first pipeline, the third pipeline, and the atmospheric connection, thereby achieving pressure balance between the closed test tube and the atmospheric pressure. After achieving pressure balance, the first switching structure is controlled to switch from the second working state to the first working state, connecting the first and second pipelines, thereby connecting the sampling needle and the sampling drive through the first and second pipelines for subsequent sampling and sample separation operations. In this application, by adding the first switching structure, the third pipeline, the liquid discharge drive, and the atmospheric connection to the original pipelines to achieve pressure balance in the closed test tube, the sampling needle can be a traditional single-channel sampling needle, effectively avoiding the problems associated with using dual-channel sampling needles. Therefore, the technical solution of this application can effectively solve the problems of high cost and difficulty in cleaning sampling needles in related technologies. Attached Figure Description

[0016] The accompanying drawings, which form part of this application, are used to provide a further understanding of the present invention. The illustrative embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an undue limitation of the present invention. In the drawings:

[0017] Figure 1 A liquid circuit diagram of a sampling component of a blood cell analyzer according to the present invention is shown, wherein the first switching structure is a first three-way valve;

[0018] Figure 2 A liquid circuit diagram of a sampling component of a blood cell analyzer according to the present invention is shown, wherein the first switching structure consists of a first three-way pipe joint, a first on-off valve, and a second on-off valve;

[0019] Figure 3 A liquid circuit diagram of a sampling component of a blood cell analyzer according to the present invention is shown, wherein the draining drive is a rotary air pump and the first switching structure is a first three-way valve;

[0020] Figure 4 A liquid circuit diagram of a sampling component of a blood cell analyzer according to the present invention is shown, wherein the draining drive is a rotary air pump and the second switching structure is a second three-way valve;

[0021] Figure 5 A liquid circuit diagram of a sampling component of a blood cell analyzer according to the present invention is shown, wherein the draining drive is a rotary air pump and the second switching structure consists of a second three-way pipe joint and a third on / off valve;

[0022] Figure 6 A diagram showing the fitting relationship between the sampling needle and the cleaning swab in one embodiment of the sampling assembly of the blood cell analyzer according to the present invention is provided.

[0023] The above figures include the following reference numerals:

[0024] 10. Sampling needle; 11. Sampling port;

[0025] 20. Sampling drive component; 21. Top opening; 22. Side opening;

[0026] 30. First pipeline; 40. Second pipeline; 50. Third pipeline; 51. First sub-pipeline; 52. Second sub-pipeline;

[0027] 60. First switching structure; 61. First three-way valve; 62. First three-way pipe joint; 63. First on / off valve; 64. Second on / off valve;

[0028] 70. Drainage drive component; 71. Rotary air pump;

[0029] 90. Second switching structure; 91. Second three-way valve; 92. Second three-way pipe joint; 93. Third shut-off valve;

[0030] 100. Cleaning swab; 110. Air filter; 120. Fourth pipeline; 130. Liquid storage container; 140. Fifth shut-off valve. Detailed Implementation

[0031] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. The following description of at least one exemplary embodiment is merely illustrative and is in no way intended to limit the present utility model or its application or use. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the scope of protection of the present utility model.

[0032] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0033] Unless otherwise specifically stated, the relative arrangement, numerical expressions, and values ​​of the components and steps described in these embodiments do not limit the scope of this invention. It should also be understood that, for ease of description, the dimensions of the various parts shown in the drawings are not drawn to actual scale. Techniques, methods, and devices known to those skilled in the art may not be discussed in detail, but where appropriate, such techniques, methods, and devices should be considered part of the specification. In all examples shown and discussed herein, any specific values ​​should be interpreted as merely exemplary and not as limitations. Therefore, other examples of exemplary embodiments may have different values. It should be noted that similar reference numerals and letters in the following drawings denote similar items; therefore, once an item is defined in one drawing, it need not be further discussed in subsequent drawings.

[0034] like Figure 1As shown, this application provides a blood cell analyzer. An embodiment of the blood cell analyzer includes a sampling component, a processing component, a detection component, and an analysis component. The sampling component includes a sampling needle 10, a sampling drive 20, a first conduit 30, a second conduit 40, a third conduit 50, a first switching structure 60, a draining drive 70, and an atmospheric communication component. The two ends of the first conduit 30 are connected to the sampling needle 10 and the first switching structure 60, respectively. The two ends of the second conduit 40 are connected to the first switching structure 60 and the sampling drive 20, respectively. The two ends of the third conduit 50 are connected to the first switching structure 60 and the draining drive 70, respectively. The atmospheric communication component is disposed on the third conduit 50 or on the draining drive 70 and connects the third conduit 50 to the atmosphere. The first switching structure 60... The switching structure 60 has a first working state and a second working state. When the first switching structure 60 is in the first working state, it connects the first pipeline 30 and the second pipeline 40 and disconnects the third pipeline 50, so that the sampling needle 10 and the sampling drive 20 are connected. When the first switching structure 60 is in the second working state, it connects the first pipeline 30 and the third pipeline 50 and disconnects the second pipeline 40, so that the sampling needle 10 and the drain drive 70 are connected. The drain drive 70 can drive the liquid in the sampling needle 10, the first pipeline 30 and the third pipeline 50 to be discharged, so that when the sampling needle 10 is inserted into the closed test tube, the closed test tube can be depressurized by communicating with the atmosphere through the sampling needle 10, the first pipeline 30 and the third pipeline 50.

[0035] Applying the technical solution of this embodiment, before sampling, the first switching structure 60 is controlled to be in the second working state, so that the first pipeline 30 and the third pipeline 50 are connected. The liquid discharge drive 70 drives the liquid in the sampling needle 10, the first pipeline 30 and the third pipeline 50 to be discharged, and the atmospheric connector connects the third pipeline 50 to the atmosphere. Then, the sampling needle 10 is inserted into the closed test tube to be sampled. The closed test tube is connected to the atmosphere through the sampling needle 10, the first pipeline 30, the third pipeline 50 and the atmospheric connector, thereby achieving a balance between the pressure in the closed test tube and the atmospheric pressure. After the pressure balance is achieved, the first switching structure 60 is controlled to switch from the second working state to the first working state, so that the first pipeline 30 and the second pipeline 40 are connected, thereby connecting the sampling needle 10 and the sampling drive 20 through the first pipeline 30 and the second pipeline 40 for subsequent sampling and sample separation operations. In this embodiment, by adding a first switching structure 60, a third pipeline 50, a drain drive component 70, and an atmospheric communication component to the original pipeline, pressure balance in the sealed test tube is achieved. This allows the sampling needle 10 to use a traditional single-channel sampling needle, which has advantages such as easy cleaning, simple structure, low manufacturing cost, high strength, and high reliability. It effectively avoids the problems associated with using dual-channel sampling needles. Therefore, the technical solution of this embodiment effectively solves the problems of high cost and difficulty in cleaning sampling needles in related technologies.

[0036] The blood cell analyzer includes a sampling component, a processing component, a detection component, and an analysis component. The sampling component is used to extract blood samples from sealed test tubes and transport them to the processing component. The processing component is used to process the blood samples, such as diluting them or mixing them with reagents like hemolysants. The detection component is used to detect the processed blood samples using optical and / or electrical detection methods. The analysis component is used to process and analyze the data acquired by the detection component to generate a test report.

[0037] Specifically, the liquid discharge drive 70 can be a power source for pushing liquid out or a power source for sucking liquid; this application does not limit this.

[0038] It should be noted that when performing pressure equalization in the sealed test tube, the sampling needle 10, the first tubing 30, and the third tubing 50 must first be connected to the atmosphere, i.e., a drainage operation must be performed first. After the drainage operation is completed, the sampling needle 10 is inserted into the sealed test tube to release pressure. When inserting the sampling needle 10 into the sealed test tube, the sampling port 11 of the sampling needle 10 must be positioned above the liquid surface inside the sealed test tube. After the pressure is released, the inner and outer walls of the sampling needle 10 need to be cleaned, and then the sampling needle 10, the first tubing 30, and the second tubing 40 are refilled with liquid.

[0039] After the liquid filling is completed, the residual pressure in the sealed test tube is almost completely released. The sampling needle 10, the first tubing 30, and the second tubing 40 are filled with liquid (except for the isolation air column stored in the needle tip). The liquid can be considered an incompressible medium, i.e., a rigid fluid. The sampling needle 10 can directly aspirate the sample, and the aspirated sample volume is basically the same as the preset sample volume, which has the advantages of high sampling accuracy and good repeatability. After sampling is completed, before the sample is divided for measurement, in order to further ensure accuracy, only a small portion of the preset sample near the needle tip and the needle tail of the sampling needle 10 needs to be discarded (e.g., 1-3 μL). There is no need to discard a large portion of the sample at the needle tip and the needle tail (usually 5-8 μL is left at the needle tip and the needle tail). There is no need to increase the sampling volume to compensate for the retraction of the sample in the needle that has not been fully depressurized. This scheme can achieve accurate sampling and division with a small sampling volume.

[0040] like Figure 1 As shown, the first switching structure 60 includes a first three-way valve 61, which has a first valve port, a second valve port, and a third valve port. A first pipeline 30 is connected to the first valve port, a second pipeline 40 is connected to the second valve port, and a third pipeline 50 is connected to the third valve port. When the first switching structure 60 is in a first working state, the first and second valve ports are connected, and the third valve port is disconnected from both the first and second valve ports. When the first switching structure 60 is in a second working state, the first and third valve ports are connected, and the second valve port is disconnected from both the first and third valve ports. Specifically, the first valve port is the C-end (common end) of the first three-way valve 61, the second valve port is the NO-end (normally open end) of the first three-way valve 61, and the third valve port is the NC-end (normally closed end) of the first three-way valve 61. Using the three-way valve as the first switching structure 60 enables the connection between the first pipeline 30 and the second pipeline 40 or the third pipeline 50, offering advantages such as simple structure and ease of control.

[0041] Besides using a three-way valve as the first switching structure 60, a three-way pipe fitting can also be used in conjunction with two on / off valves as the first switching structure 60. Specifically, such as... Figure 2As shown, the first switching structure 60 includes a first three-way connector 62, a first on-off valve 63, and a second on-off valve 64. The first three-way connector 62 has a first interface, a second interface, and a third interface. The first pipeline 30 is connected to the first interface. The first on-off valve 63 is located between the second interface and the second pipeline 40. The second on-off valve 64 is located between the third interface and the third pipeline 50. By controlling the first on-off valve 63 and the second on-off valve 64 to be open or closed, the first switching structure 60 can switch between a first working state and a second working state, which has the advantages of simple structure and easy control. Specifically, when pressure balancing is required, the first on-off valve 63 is controlled to be in the open state and the second on-off valve 64 is controlled to be in the open state; when sampling and sample separation are required, the first on-off valve 63 is controlled to be in the open state and the second on-off valve 64 is controlled to be in the closed state.

[0042] like Figures 3 to 5 As shown, the draining drive 70 is a rotary air pump 71. When the rotary air pump 71 is working, it pumps air into the third pipeline 50, the first pipeline 30, and the sampling needle 10, so that the liquid in the sampling needle 10, the first pipeline 30, and the third pipeline 50 is discharged from the sampling port 11 of the sampling needle 10. The atmospheric connection is the air inlet of the rotary air pump 71. Using the rotary air pump 71 as the draining drive 70 allows the air inlet of the rotary air pump 71 to be directly used as an atmospheric connection, eliminating the need for an additional valve structure as an atmospheric connection. This reduces the cost of pipeline layout and simplifies the control during the pressure balancing process.

[0043] like Figure 3 As shown, when the C end of the first three-way valve 61 is connected to the NO end, the interior of the first three-way valve 61 is connected to the sampling drive 20, and the liquid in the first pipeline 30, the first three-way valve 61 and the second pipeline 40 can flow under the action of the sampling drive 20, avoiding the long-term retention of liquid between the C end and the NO end of the first three-way valve 61; when the C end of the first three-way valve 61 is connected to the NC end, the rotary air pump 71 blows air into the third pipeline 50, the first three-way valve 61 and the first pipeline 30, which can also prevent the long-term retention of liquid between the C end and the NC end of the first three-way valve 61.

[0044] Because the rotary air pump 71 has a unidirectional structure, air can only be injected into the third pipe 50 from the air inlet of the rotary air pump 71, and the gas inside the sealed test tube cannot be discharged outward through the rotary air pump 71. In other words, using the rotary air pump 71 as the discharge drive 70 is only suitable for scenarios where the sealed test tube is under negative pressure and air needs to be injected into the sealed test tube, but it is not suitable for scenarios where the sealed test tube is under positive pressure and gas needs to be discharged into the atmosphere.

[0045] To solve the above problems, such as Figure 4 and Figure 5As shown, the sampling assembly also includes a second switching structure 90 disposed on the third conduit 50. The second switching structure 90 divides the third conduit 50 into a first sub-conduit 51 located near the first switching structure 60 and a second sub-conduit 52 located near the draining drive 70. The second switching structure 90 has a third working state and a fourth working state. When the second switching structure 90 is in the third working state, it connects the first sub-conduit 51 and the second sub-conduit 52 and disconnects from the atmosphere. When the second switching structure 90 is in the fourth working state, it connects the first sub-conduit 51 and the atmosphere. By adding the second switching structure 90, after the draining drive 70 drains the liquid from the sampling needle 10, the first conduit 30, and the third conduit 50, the third conduit 50 can be connected to the atmosphere through the second switching structure 90 to balance the positive pressure inside the sealed test tube.

[0046] In this embodiment, the sampling channel (specifically including the first tube 30 and the second tube 40) is reused to depressurize the pressure inside the sealed test tube. This allows for complete pressure release within the test tube and can accommodate various residual pressure ranges within the sealed test tube. The amount of blood sample discarded from the head and tail of the sampling needle 10 is small, resulting in a low total blood volume required. Furthermore, due to the reduced number of components in the sampling assembly, the system structure is simple, offering advantages such as low cost and easier miniaturization of the instrument.

[0047] The sampling channel needs to be made of rigid tubing and should be as short as possible to resist the impact of tubing deformation on sampling accuracy.

[0048] like Figure 4As shown, the second switching structure 90 includes a second three-way valve 91, which has a fourth valve port, a fifth valve port, and a sixth valve port. A first sub-pipeline 51 is connected to the fourth valve port, a second sub-pipeline 52 is connected to the fifth valve port, and the sixth valve port is open to the atmosphere. When the second switching structure 90 is in the third operating state, the fourth and fifth valve ports are connected, and the sixth valve port is disconnected from both the fourth and fifth valve ports. When the second switching structure 90 is in the fourth operating state, the fourth and sixth valve ports are connected. Specifically, the fourth valve port is the C-end (common end) of the second three-way valve 91, the fifth valve port is the NO-end (normally open end) of the second three-way valve 91, and the sixth valve port is the NC-end (normally closed end) of the second three-way valve 91. When drainage of the sampling needle 10, the first tubing 30, and the third tubing 50 is required, the second switching structure 90 is controlled to the third operating state; when communication between the closed test tube and the atmosphere is required (especially for cases where the closed test tube has positive pressure), the second switching structure 90 is controlled to the fourth operating state. A three-way valve is used as the second switching structure 90 to allow the third tubing 50 to be directly connected to the atmosphere, enabling the sampling assembly to be suitable for various pressure ranges within the closed test tube (e.g., the closed test tube can be under positive or negative pressure).

[0049] Besides using a three-way valve as the second switching structure 90, a combination of a three-way pipe fitting and an on / off valve can also be used as the second switching structure 90. For example... Figure 5 As shown, the second switching structure 90 includes a second three-way connector 92 and a third on-off valve 93. The second three-way connector 92 has a fourth interface, a fifth interface, and a sixth interface. The first sub-pipeline 51 is connected to the fourth interface, the second sub-pipeline 52 is connected to the fifth interface, and the sixth interface is connected to the third on-off valve 93. When it is necessary to drain the sampling needle 10, the first pipeline 30, and the third pipeline 50, the third on-off valve 93 is controlled to be in the off state, so that the draining drive 70 is connected to the first sub-pipeline 51 through the second three-way connector 92. When it is necessary to connect the closed test tube to the atmosphere (especially for cases where there is positive pressure inside the closed test tube), the third on-off valve 93 is controlled to be in the on state, so that the third pipeline 50 can be directly connected to the atmosphere.

[0050] In this embodiment, the second switching structure 90 includes a second three-way connector 92 and a third shut-off valve 93. The second three-way connector 92 has a fourth interface, a fifth interface, and a sixth interface. The first sub-pipe 51 is connected to the fourth interface, the second sub-pipe 52 is connected to the fifth interface, and the sixth interface is connected to the third shut-off valve 93. Liquid is unlikely to remain inside the three-way connector structure for extended periods. Even if liquid remains in the second three-way connector 92 and its connected pipes, it can be removed by blowing air into it using a rotary air pump 71.

[0051] Specifically, such as Figure 5As shown, the NC end of the first three-way valve 61 can be disconnected, the third shut-off valve 93 can connect the second three-way connector 92 to the atmosphere, and air can be blown into the pipeline by the rotary air pump 71 to blow away the liquid in the second sub-pipe 52, the second three-way connector 92 and the third shut-off valve 93; the NC end of the first three-way valve 61 can be connected to the C end, the third shut-off valve 93 can block the second three-way connector 92 from the atmosphere, and air can be blown into the pipeline by the rotary air pump 71 to blow away the liquid in the second sub-pipe 52, the second three-way connector 92, the first sub-pipe 51, the first three-way valve 61, the first pipeline 30 and the sampling needle 10.

[0052] like Figure 6 As shown, the sampling port 11 is located on the side wall of the sampling needle 10. The sampling assembly also includes a cleaning swab 100 sleeved on the sampling needle 10. The sampling needle 10 and the cleaning swab 100 are slidably engaged and have a drainage engagement state where the cleaning swab 100 is located outside the sampling port 11. When a drainage drive 70, such as a rotary air pump 71, is used to push liquid outward, the sampling needle 10 and the cleaning swab 100 are controlled to be in the drainage engagement state, so that the liquid in the third pipeline 50, the first pipeline 30, and the sampling needle 10 can enter the cleaning swab 100 through the sampling port 11 and then be discharged through the cleaning swab 100.

[0053] Specifically, such as Figure 6 As shown, the cleaning swab 100 has an inlet and an outlet. The inlet is located below the outlet and is connected to the cleaning fluid storage chamber. The outlet is connected to the waste fluid chamber. The cleaning swab 100 can be used to clean the outer wall of the sampling needle 10. When cleaning the outer wall of the sampling needle 10, cleaning fluid is injected into the cleaning swab 100 through the inlet. Then, the sampling needle 10 and the cleaning swab 100 slide relative to each other, allowing the cleaning fluid to thoroughly clean the outer wall of the sampling needle 10. The cleaning fluid is then discharged into the waste fluid chamber through the outlet. When draining the liquid from the third tubing 50, the first tubing 30, and the sampling needle 10, the drained liquid first enters the cleaning swab 100 and then is discharged into the waste fluid chamber through the outlet of the cleaning swab 100.

[0054] In some feasible implementations, the draining drive 70 is a positive pressure source (e.g., a positive pressure gas storage tank) or a negative pressure source, and the atmospheric connection is a fourth on-off valve, which is installed on the third pipeline 50 or on the draining drive 70. During the draining operation, the fourth on-off valve is controlled to be in the off state to prevent the third pipeline 50 or the draining drive 70 from being connected to the atmosphere and affecting the draining operation; after the draining operation is completed, the fourth on-off valve is controlled to be in the on state, allowing the third pipeline 50 to be connected to the atmosphere for pressure balancing of the sealed test tube.

[0055] The drain drive 70 can also be a diaphragm liquid pump or a diaphragm air pump.

[0056] like Figure 3 As shown, an air filter 110 is installed on the atmospheric connector. When outside air passes through the atmospheric connector and enters the sealed test tube via the third pipe 50, the first pipe 30, and the sampling needle 10, the air filter 110 can block dust, lint, and other impurities in the air, preventing the sample in the sealed test tube from being contaminated.

[0057] Similarly, as Figure 4 As shown, when an additional second switching structure 90 is provided to connect the third pipeline 50 to the atmosphere, an air filter can also be provided at the atmosphere connection end of the second switching structure 90.

[0058] like Figures 1 to 5 As shown, the sampling drive unit 20 has a top opening 21 and a side opening 22. The top opening 21 is connected to the second pipeline 40. The sampling assembly also includes a fourth pipeline 120, a liquid storage container 130, and a fifth on / off valve 140. The liquid storage container 130 is used to store cleaning fluid. The fourth pipeline 120 is connected between the side opening 22 and the liquid storage container 130. The fifth on / off valve 140 is disposed on the fourth pipeline 120. The top opening 21 is connected to the second pipeline 40, allowing the sampling drive unit 20 to drive the sampling needle 10 to perform sampling and sample separation through the second pipeline 40 and the first pipeline 30. The side opening 22 is connected to the liquid storage container 130 through the fourth pipeline 120 to draw diluent from the inside of the liquid storage container 130 to clean the various pipelines and the sampling needle 10.

[0059] The following describes the steps for depressurizing a sealed test tube using the sampling assembly of this embodiment:

[0060] In the initial state, the sampling needle 10, the first tube 30 and the second tube 40 are filled with liquid, the first switching structure 60 is in the first working state, and the sampling needle 10, the first tube 30, the second tube 40 and the sampling drive 20 are connected.

[0061] The first switching structure 60 is controlled to switch from the first working state to the second working state, that is, the sampling needle 10 is connected to the draining drive 70 through the first tube 30 and the third tube 50. The draining drive 70 is activated to either draw out or drain the liquid in the third tube 50, the first tube 30 and the sampling needle 10 (when draining, the draining drive 70 flushes the liquid out from the sampling port 11 of the sampling needle 10 and drains it away by the cleaning swab 100; when drawing out, the liquid is drawn into the draining drive 70 and then drained, or directly drained by the draining drive 70), and the third tube 50 is connected to the atmosphere.

[0062] The sampling needle 10 is inserted into the sealed test tube, and the sampling port 11 is higher than the liquid level of the sample. The gas inside the sealed test tube is connected to the atmosphere by the sampling channel of the sampling needle 10, the first tube 30 and the third tube 50, so as to release pressure and gas.

[0063] Remove the sampling needle 10 from the sealed test tube, clean the inner and outer walls of the sampling needle 10, and refill the sampling needle 10, the first tubing 30, and the second tubing 40 with liquid.

[0064] When cleaning the inner wall of the sampling needle 10, the fifth on / off valve 140 is controlled to be in the conducting state. The diluent in the storage container 130 fills the sampling needle 10 through the fourth pipeline 120, the sampling drive 20, the second pipeline 40 and the first pipeline 30, and cleans the inner wall of the sampling needle 10. When cleaning the outer wall of the sampling needle 10, the outer wall of the sampling needle 10 is cleaned by injecting cleaning fluid into the cleaning swab 100 and controlling the relative sliding of the sampling needle 10 and the cleaning swab 100.

[0065] In the description of this utility model, it should be understood that "multiple" means two or more. Directional terms such as "front, back, up, down, left, right," "horizontal, vertical, perpendicular, horizontal," and "top, bottom" indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings. These terms are used solely for the convenience of describing this utility model and simplifying the description. Unless otherwise stated, these directional terms do not indicate or imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore should not be construed as limiting the scope of protection of this utility model. The directional terms "inner" and "outer" refer to the inner or outer contours relative to the outline of each component itself.

[0066] For ease of description, spatial relative terms such as "above," "on top of," "on the upper surface of," "above," etc., are used herein to describe the spatial positional relationship of a device or feature as shown in the figures to other devices or features. It should be understood that spatial relative terms are intended to encompass different orientations in use or operation beyond the orientation of the device as described in the figures. For example, if the device in the figures were inverted, a device described as "above" or "on top of" other devices or structures would subsequently be positioned as "below" or "under" other devices or structures. Thus, the exemplary term "above" can include both "above" and "below." The device may also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used herein will be interpreted accordingly.

[0067] Furthermore, it should be noted that the use of terms such as "first" and "second" to define components is merely for the purpose of distinguishing the corresponding components. Unless otherwise stated, the above terms have no special meaning and therefore cannot be construed as limiting the scope of protection of this utility model.

[0068] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A blood cell analyzer, comprising a sampling component, a processing component, a detection component, and an analysis component, characterized in that, The sampling assembly includes a sampling needle (10), a sampling drive (20), a first conduit (30), a second conduit (40), a third conduit (50), a first switching structure (60), a drain drive (70), and an atmospheric communication component, wherein... The two ends of the first conduit (30) are connected to the sampling needle (10) and the first switching structure (60) respectively; the two ends of the second conduit (40) are connected to the first switching structure (60) and the sampling drive (20) respectively; the two ends of the third conduit (50) are connected to the first switching structure (60) and the drain drive (70) respectively; and the atmospheric connector is disposed on the third conduit (50) or on the drain drive (70) and is capable of connecting the third conduit (50) and the atmosphere. The first switching structure (60) has a first working state and a second working state. When the first switching structure (60) is in the first working state, the first switching structure (60) connects the first pipeline (30) and the second pipeline (40) and disconnects the third pipeline (50) so that the sampling needle (10) and the sampling drive (20) are connected. When the first switching structure (60) is in the second working state, the first switching structure (60) connects the first pipeline (30) and the third pipeline (50) and disconnects the second pipeline (40) so that the sampling needle (10) and the drain drive (70) are connected. The drain drive (70) can drive the liquid in the sampling needle (10), the first pipeline (30) and the third pipeline (50) to be discharged so that when the sampling needle (10) is inserted into the closed test tube, the closed test tube can be depressurized by communicating with the atmosphere through the sampling needle (10), the first pipeline (30) and the third pipeline (50).

2. The blood cell analyzer according to claim 1, characterized in that, The first switching structure (60) includes a first three-way valve (61), which has a first valve port, a second valve port, and a third valve port. The first pipeline (30) is connected to the first valve port, the second pipeline (40) is connected to the second valve port, and the third pipeline (50) is connected to the third valve port. When the first switching structure (60) is in the first working state, the first valve port and the second valve port are connected, and the third valve port is disconnected from the first valve port and the second valve port. When the first switching structure (60) is in the second working state, the first valve port and the third valve port are connected, and the second valve port is disconnected from the first valve port and the third valve port.

3. The blood cell analyzer according to claim 1, characterized in that, The first switching structure (60) includes a first three-way pipe joint (62), a first on / off valve (63), and a second on / off valve (64). The first three-way pipe joint (62) has a first interface, a second interface, and a third interface. The first pipeline (30) is connected to the first interface. The first on / off valve (63) is disposed between the second interface and the second pipeline (40). The second on / off valve (64) is disposed between the third interface and the third pipeline (50).

4. The blood cell analyzer according to any one of claims 1 to 3, characterized in that, The drain drive (70) is a rotary air pump (71). When the rotary air pump (71) is working, it pumps air into the third pipeline (50), the first pipeline (30) and the sampling needle (10) so that the liquid in the sampling needle (10), the first pipeline (30) and the third pipeline (50) is discharged from the sampling port (11) of the sampling needle (10). The atmospheric communication device is the air inlet of the rotary air pump (71).

5. The blood cell analyzer according to claim 4, characterized in that, The sampling component further includes a second switching structure (90) disposed on the third pipeline (50). The second switching structure (90) divides the third pipeline (50) into a first sub-pipeline (51) near the first switching structure (60) and a second sub-pipeline (52) near the drain drive (70). The second switching structure (90) has a third working state and a fourth working state. When the second switching structure (90) is in the third working state, the second switching structure (90) connects the first sub-pipeline (51) and the second sub-pipeline (52) and disconnects from the atmosphere. When the second switching structure (90) is in the fourth working state, the second switching structure (90) connects the first sub-pipeline (51) and the atmosphere.

6. The blood cell analyzer according to claim 5, characterized in that, The second switching structure (90) includes a second three-way valve (91), which has a fourth valve port, a fifth valve port, and a sixth valve port. The first sub-pipeline (51) is connected to the fourth valve port, the second sub-pipeline (52) is connected to the fifth valve port, and the sixth valve port is open to the atmosphere. When the second switching structure (90) is in the third working state, the fourth valve port and the fifth valve port are connected, and the sixth valve port is disconnected from the fourth and fifth valve ports. When the second switching structure (90) is in the fourth working state, the fourth valve port and the sixth valve port are connected; or... The second switching structure (90) includes a second three-way pipe joint (92) and a third on / off valve (93). The second three-way pipe joint (92) has a fourth interface, a fifth interface and a sixth interface. The first sub-pipe (51) is connected to the fourth interface, the second sub-pipe (52) is connected to the fifth interface, and the sixth interface is connected to the third on / off valve (93).

7. The blood cell analyzer according to claim 4, characterized in that, The sampling port (11) is disposed on the side wall of the sampling needle (10). The sampling assembly also includes a cleaning swab (100) sleeved on the sampling needle (10). The sampling needle (10) and the cleaning swab (100) are slidably engaged and the cleaning swab (100) is located outside the sampling port (11) in a draining engagement state.

8. The blood cell analyzer according to any one of claims 1 to 3, characterized in that, The drain drive (70) is a positive pressure source or a negative pressure source, and the atmospheric connection is a fourth shut-off valve. The fourth shut-off valve is installed on the third pipeline (50) or on the drain drive (70).

9. The blood cell analyzer according to any one of claims 1 to 3, characterized in that, An air filter (110) is provided on the atmospheric communication component.

10. The blood cell analyzer according to any one of claims 1 to 3, characterized in that, The sampling drive (20) has a top opening (21) and a side opening (22). The top opening (21) is connected to the second pipeline (40). The sampling assembly also includes a fourth pipeline (120), a liquid storage container (130), and a fifth on / off valve (140). The liquid storage container (130) is used to store cleaning fluid. The fourth pipeline (120) is connected between the side opening (22) and the liquid storage container (130). The fifth on / off valve (140) is disposed on the fourth pipeline (120).

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