A probe device for genetic mutation detection

Abstract

The utility model discloses a kind of probe devices for gene mutation detection, including probe platform and connecting frame, the upper surface of the probe platform is equipped with multiple support columns and guide, the top of the guide and the top of multiple support columns are jointly connected with square plate, the upper surface of the square plate is equipped with electric cylinder, the output end of the electric cylinder is fixedly connected with transmission plate, the bottom surface of the transmission plate is connected with connecting box, the outer surface of the connecting box is equipped with fastener.This device is jointly constituted by square slide column in connecting box inner wall, sliding plate, spring, square block and square mouth on connecting frame and constitutes quick connection structure, when connecting frame is inserted into the strip-shaped hole of connecting box bottom surface, spring pushes sliding plate and makes square block insert into square mouth, realize the quick connection of connecting frame and connecting box, it is easy and fast to operate and install more convenient, when different specifications of probe are conveniently replaced, the replacement probe time when detecting is saved, and work efficiency is improved.

Description

Technical Field

[0001] This invention relates to the field of biological detection, and in particular to a probe device for detecting gene mutations. Background Technology

[0002] Biological detection aims to obtain information about the internal state, function, and interaction with the external environment of an organism through the analysis and detection of biological samples. It can provide basic information about the organism and provide scientific basis for disease diagnosis, environmental monitoring, and food safety assessment. Gene mutation detection is an important molecular biology technique that can be used to detect gene mutations in an individual. The principle of gene mutation detection is based on the analysis and comparison of gene sequences. By measuring the DNA sequence of the sample, it identifies whether there is a mutation. In order to quickly and accurately identify and detect gene mutation sites, probe devices are used.

[0003] Gene mutation detection plays a crucial role in modern medical and biological research. It helps doctors accurately diagnose diseases and develop personalized treatment plans, while also providing key information for the research and prevention of genetic diseases. However, existing gene mutation detection probe devices have many shortcomings, limiting the efficiency and accuracy of the detection. During use, the probes come into contact with the sample and may become contaminated or worn, which can affect the accuracy of the detection. To avoid inaccurate test results and subsequent treatment decisions caused by worn or contaminated probes, probes need to be replaced regularly to ensure the accuracy and reliability of gene detection.

[0004] According to Chinese Patent No. CN222064544U, a probe device for detecting gene mutations includes a protective tube, a battery box fixedly installed on the top of the protective tube, a T-shaped rod slidably installed above the inner cavity of the protective tube, a piston fixedly installed at the bottom of the T-shaped rod and attached to the inner cavity of the protective tube, a sensing device fixedly installed at the bottom of the piston, and a probe fixedly installed at the bottom of the sensing device.

[0005] However, in practical applications, different test samples and test equipment have different requirements for probes. For the detection of some special samples, probes of specific length or shape may be required. When it is necessary to change probes of different specifications, multiple parts often need to be opened, which is cumbersome and inconvenient. Therefore, we propose a probe device for gene mutation detection to solve the above problems. Utility Model Content

[0006] The purpose of this invention is to provide a probe device for detecting gene mutations, thereby solving the problems mentioned in the background section. To achieve the above objective, this invention provides the following technical solution: A probe device for detecting gene mutations includes a probe stage and a connecting frame. Multiple support columns and guide members are mounted on the upper surface of the probe stage. A square plate is connected to the top of the guide members and the tops of the support columns. An electric cylinder is mounted on the upper surface of the square plate. A transmission plate is fixedly connected to the output end of the electric cylinder. A connecting box is connected to the bottom surface of the transmission plate. Fasteners are mounted on the outer surface of the connecting box. A square sliding column is mounted on the inner wall of the connecting box. A fixing plate is mounted on the outer surface of the square sliding column and the inner wall of the connecting box. Two sliding plates are slidably connected to the outer surface of the square sliding column. A spring is connected to the outer surface of each sliding plate. One end of each spring is connected to the outer surface of the fixing plate. A square block and a pressing block are connected to the outer surface of each sliding plate. A square opening adapted to the square block is provided on the outer surface of the connecting frame. A probe is connected to the bottom surface of the connecting frame.

[0007] In a further embodiment, the bottom surface of the connecting box is provided with a strip-shaped hole adapted to the connecting frame, and the outer surface of the connecting box is provided with a through-hole adapted to the pressing block.

[0008] In a further embodiment, the guide includes a plurality of sliding pillars mounted on the probe stage, each of the sliding pillars having a sliding sleeve slidably connected to its outer surface, and each sliding sleeve having its outer surface connected to the outer surface of the transmission plate.

[0009] In a further embodiment, the inner wall of the connecting box is connected to a plurality of limiting plates, and the limiting plates are located below the square sliding column.

[0010] In a further embodiment, the fastener includes a frame mounted on the outer surface of the connecting box and a connecting groove plate mounted on the outer surface of the connecting frame. The outer surface of the frame is inlaid with a screw, and the screw is provided with a fastening nail inside, and the fastening nail matches the connecting groove plate.

[0011] In a further embodiment, a tray is provided on the upper surface of the probe station.

[0012] Compared with the prior art, the beneficial effects of this utility model are: I. This device, through the square sliding column, sliding plate, spring, square block on the inner wall of the connecting box, and the square opening on the connecting frame, constitutes a quick connection structure. When the connecting frame is inserted into the strip hole on the bottom of the connecting box, the spring pushes the sliding plate to insert the square block into the square opening, realizing the quick connection between the connecting frame and the connecting box. The operation is simple and quick, and the installation is more convenient. It also makes it easier to change probes of different specifications, saving probe replacement time during testing and improving work efficiency.

[0013] Second, this device uses fasteners including a frame, a screw barrel, fastening nails, and a connecting groove plate. By screwing the fastening nails into the screw barrel and matching them with the connecting groove plate, the connecting frame and the connecting box can be further fixed, preventing the connecting frame from loosening or falling off during the testing process. This ensures the stability of the probe device during the testing process and thus ensures the reliability of the testing results. Attached Figure Description

[0014] Figure 1 This is a frontal three-dimensional schematic diagram of a probe device for detecting gene mutations.

[0015] Figure 2 This is a posterior cross-sectional view of a probe device for detecting gene mutations.

[0016] Figure 3 This is a schematic diagram showing the separation of the connecting box and the connecting frame in a probe device for gene mutation detection.

[0017] Figure 4 This is a rear cross-sectional view of the connection box in a probe device for gene mutation detection.

[0018] In the diagram: 1. Probe station; 2. Storage tray; 3. Guide component; 301. Support column; 302. Sliding sleeve; 4. Support column; 5. Square plate; 6. Electric cylinder; 7. Transmission plate; 8. Connecting box; 9. Fastener; 901. Frame; 902. Screw; 903. Fastening nail; 904. Connecting slot plate; 10. Connecting frame; 11. Probe; 12. Square opening; 13. Strip hole; 14. Fixing plate; 15. Square sliding column; 16. Sliding plate; 17. Square block; 18. Spring; 19. Pressing block; 20. Limiting plate. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0020] Please see Figures 1-4 In this utility model, a probe device for detecting gene mutations includes a probe station 1 and a connecting frame 10. Multiple support columns 4 and guide members 3 are installed on the upper surface of the probe station 1. The top of the guide member 3 and the top of the multiple support columns 4 are connected to a square plate 5. An electric cylinder 6 is installed on the upper surface of the square plate 5. A transmission plate 7 is fixedly connected to the output end of the electric cylinder 6. A connecting box 8 is connected to the bottom surface of the transmission plate 7. Specifically, fasteners 9 are installed on the outer surface of the connecting box 8, and square sliding columns 15 are installed on the inner wall of the connecting box 8. Fixing plates 14 are installed on the outer surface of the square sliding columns 15 and the inner wall of the connecting box 8. Two sliding plates 16 are slidably connected to the outer surface of the square sliding columns 15. A spring 18 is connected to the outer surface of each sliding plate 16. The reset performance of the spring 18 is mainly reflected in its ability to automatically return to its original state after the external force is removed. The spring 18 stores energy through its elastic deformation. When the external force disappears, this energy will be released, so that the spring 18 returns to its original shape and position. In this design, one end of each spring 18 is connected to the outer surface of the fixed plate 14, and the outer surface of each sliding plate 16 is connected to a square block 17 and a pressing block 19. The outer surface of the connecting frame 10 has a square opening 12 that matches the square block 17. A probe 11 is connected to the bottom surface of the connecting frame 10. The electric cylinder 6 on the probe station 1 can drive the connecting box 8 to move up and down through the transmission plate 7 at the output end. This allows the connecting frame 10 and the probe 11 on the bottom surface of the connecting frame 10 to be precisely positioned in the vertical direction to suit the needs of the connecting frame 10. To meet different testing needs and sample locations, and to ensure that the probe 11 can accurately contact the test sample, thereby improving the accuracy of gene mutation detection, the square sliding column 15, sliding plate 16, spring 18, square block 17, and square opening 12 on the connecting frame 10 together constitute a quick connection structure. When the connecting frame 10 is inserted into the strip hole 13 on the bottom surface of the connecting box 8, the spring 18 pushes the sliding plate 16 to insert the square block 17 into the square opening 12, which can realize the quick connection and disassembly of the connecting frame 10 and the connecting box 8. The operation is simple and quick, and the installation is more convenient.

[0021] Furthermore, in this embodiment of the present invention, the guide member 3 includes a plurality of sliding pillars 301 mounted on the probe station 1. Each sliding pillar 301 has a sliding sleeve 302 slidably connected to its outer surface. The outer surface of each sliding sleeve 302 is connected to the outer surface of the transmission plate 7. The guide member 3 is composed of a plurality of sliding pillars 301 and sliding sleeves 302. The sliding sleeves 302 are connected to the transmission plate 7. The sliding pillars 301 provide stable guidance for the movement of the transmission plate 7, ensuring that the transmission plate 7 will not deviate or shake when it moves. This allows the connecting box 8, the connecting frame 10 and the probe 11 to move along an accurate trajectory, further improving the positioning accuracy of the probe 11.

[0022] Furthermore, the bottom surface of the connecting box 8 is provided with a strip-shaped hole 13 that matches the connecting frame 10, and the outer surface of the connecting box 8 is provided with a through-hole that matches the pressing block 19. The strip-shaped hole 13 facilitates the movement, disassembly, and installation of the connecting frame 10. The through-hole on the outer surface of the connecting box 8 matches the pressing block 19. When it is necessary to disassemble the connecting frame 10, the operator can press the pressing block 19 to overcome the elastic force of the spring 18 and make the square block 17 disengage from the square opening 12, ensuring the safety and controllability of the operation. The inner wall of the connecting box 8 is connected with multiple limiting plates 20, and the limiting plates 20 are located below the square sliding column 15. The upper surface of the probe station 1 is provided with a storage tray 2. The limiting plates 20 are located below the square sliding column 15, which can limit the range of upward movement of the connecting frame 10 and ensure its smooth installation. The storage tray 2 can be used to place tools, samples, or other related items required during the testing process, making it easier for the operator to access them.

[0023] Furthermore, the fastener 9 includes a frame 901 mounted on the outer surface of the connecting box 8 and a connecting groove plate 904 mounted on the outer surface of the connecting bracket 10. The outer surface of the frame 901 is inlaid with a screw 902, and the screw 902 is provided with a fastening nail 903 inside, and the fastening nail 903 matches the connecting groove plate 904. When the connecting frame 10 is inserted into the connecting box 8, its connecting slot plate 904 can be inserted into the frame 901. After being inserted into place, it can be moved in the screw cylinder 902 by fastening nail 903, so that the fastening nail 903 can contact the connecting slot plate 904 to position it, further fixing the connecting frame 10 and the connecting box 8, preventing the connecting frame 10 from loosening or falling off during the detection process, ensuring the stability of the probe 11 device during the detection process, and thus ensuring the reliability of the detection results; During disassembly, the fastening pin 903 must be tightened first to release the fastener from the connecting slot plate 904 so that it can be disassembled later.

[0024] The working principle of this utility model is as follows: When it is necessary to replace different probes 11, the probes 11 and the connecting bracket 10 can be inserted into the connecting box 8 through the strip hole 13. At the same time, push the pressing block 19 so that the pressing block 19 pushes the sliding plate 16 to slide along the square sliding post 15 to generate pressure on the spring 18. After inserting the square opening 12 on the connecting bracket 10 into the connecting box 8, the pressing block 19 can be released. The elastic restoring performance of the spring 18 will allow the square block 17 on the sliding plate 16 to be inserted into the square opening 12 on the connecting bracket 10, thus completing the installation of the probe 11. When disassembly is required, the above steps can be reversed to disassemble it.

[0025] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0026] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A probe device for detecting gene mutations, characterized in that, include: The probe station (1) has multiple support columns (4) and guides (3) installed on its upper surface. The top of the guides (3) and the top of the multiple support columns (4) are connected to a square plate (5). An electric cylinder (6) is installed on the upper surface of the square plate (5). The output end of the electric cylinder (6) is fixedly connected to a transmission plate (7). A connecting box (8) is connected to the bottom surface of the transmission plate (7). Fasteners (9) are installed on the outer surface of the connecting box (8). A square sliding column (15) is installed on the inner wall of the connecting box (8). A fixing plate (14) is installed on the outer surface of the square sliding column (15) and the inner wall of the connecting box (8). Two sliding plates (16) are slidably connected to the outer surface of the square sliding column (15). A spring (18) is connected to the outer surface of each sliding plate (16). One end of each spring (18) is connected to the outer surface of the fixing plate (14). A square block (17) and a pressing block (19) are connected to the outer surface of each sliding plate (16). The connecting frame (10) has a square opening (12) on its outer surface that is compatible with the square block (17), and a probe (11) is connected to the bottom surface of the connecting frame (10).

2. The probe device for detecting gene mutations according to claim 1, characterized in that, The bottom surface of the connecting box (8) is provided with a strip hole (13) that is compatible with the connecting frame (10). The outer surface of the connecting box (8) is provided with an opening that is compatible with the pressing block (19).

3. The probe device for detecting gene mutations according to claim 1, characterized in that, The guide (3) includes multiple sliding columns (301) mounted on the probe station (1), and each sliding column (301) has a sliding sleeve (302) slidably connected to its outer surface. The outer surface of each sliding sleeve (302) is connected to the outer surface of the transmission plate (7).

4. The probe device for detecting gene mutations according to claim 1, characterized in that, The inner wall of the connecting box (8) is connected to a plurality of limiting plates (20), and the limiting plates (20) are located below the square sliding column (15).

5. The probe device for detecting gene mutations according to claim 1, characterized in that, The fastener (9) includes a frame (901) mounted on the outer surface of the connecting box (8) and a connecting groove plate (904) mounted on the outer surface of the connecting frame (10). The outer surface of the frame (901) is inlaid with a screw cylinder (902); The screw barrel (902) is equipped with a fastening pin (903) inside, which matches the connecting groove plate (904).

6. The probe device for detecting gene mutations according to claim 5, characterized in that, The upper surface of the probe station (1) is provided with a tray (2).

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