Multi-windowed fluorescence immunoassay analyzer
Patent Information
- Application Number
- CN202521974228.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-09-15
- Publication Date
- 2026-09-15
- Estimated Expiration
- 2035-09-15
AI Technical Summary
[0005]然而,对于现有的这种分析仪,其仅适用于单个二维码的扫描,实际应用中,尤其是一些设置有多个二维码的多联的试剂卡(多联卡)中,显然上述的这种分析仪无法实现多个二维码信息扫码读取,因而还有待改进
本申请中,通过将扫码器设计为能够在扫码工位下沿第二方向移动,并设置第二移动机构,如此配合试剂卡上的信息码的排列方式(即沿第二方向排列),在扫码时,只需通过第二移动机构驱动扫码器沿第二方向移动,如此扫码器在沿第二方向移动过程中,便可依次对试剂卡上的信息码进行扫码读取,从而实现对多个信息码的信息读取。
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Figure CN224758537U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of biological detection instruments, and in particular to a multi-window fluorescence immunoassay analyzer. Background Technology
[0002] Fluorescence immunoassay is a commonly used detection technique in biomedical testing. This technique utilizes the property that the analyte fluoresces when excited by light of a specific wavelength for qualitative and quantitative detection. Due to its advantages such as high sensitivity, strong specificity, fast detection speed, and safety and stability, fluorescence immunoassay is widely used in clinical testing and has broad application prospects in areas such as endocrine disease detection, infectious disease detection, obstetric and gynecological disease detection, tumor marker detection, genetic disease detection, and blood and cytology testing.
[0003] The basic principle of fluorescence immunoassay is that the specific reaction process of the antibody or antigen to be tested is labeled with a fluorescent substance. Under excitation light of a specific wavelength, the fluorescent substance emits reflected fluorescence of a certain wavelength. The intensity of this fluorescence is detected by a photoelectric module, which then provides the concentration information of the analyte. Fluorescence immunoassay has advantages such as high specificity, high sensitivity, and fast detection speed, and is therefore widely used in fields such as microbial detection, viral antigen or antibody detection, hormone detection, and tumor marker detection.
[0004] Currently, there are various types of fluorescence detection devices (hereinafter referred to as analyzers) based on fluorescence immunoassay technology on the market. Among the related technologies, some analyzers, in addition to setting up a fluorescence detection module, also set up a barcode scanning module to scan the QR code on the reagent card to read the relevant information recorded in the QR code, such as the handheld fluorescence immunoassay analyzer disclosed in application number CN202420810974.5.
[0005] However, the existing analyzers are only capable of scanning a single QR code. In practical applications, especially in multi-part reagent cards with multiple QR codes, the analyzers described above are clearly unable to scan and read information from multiple QR codes, and therefore need further improvement. Utility Model Content
[0006] In order to solve at least one of the technical problems mentioned in the background art, the purpose of this application is to provide a multi-window fluorescence immunoassay analyzer.
[0007] To achieve the above objectives, this application provides the following technical solution.
[0008] This application provides a multi-window fluorescence immunoassay analyzer, comprising: The body, within which a working space is formed; A carrier for loading the reagent card to be tested; the carrier is capable of moving along a first direction within the workspace between the barcode scanning station and the testing station; A first moving mechanism is used to drive the carrier to move along a first direction; The detection module is used to perform fluorescence detection on the reagent cards that are carried into the detection station by the carrier. A barcode scanning module is used to scan and read information codes on a reagent card, wherein the reagent card has at least two information codes, and when the reagent card is loaded on a carrier, the at least two information codes are arranged sequentially along a second direction, the second direction being perpendicular to the first direction; the barcode scanning module includes at least a barcode scanner capable of scanning and reading the information codes; the barcode scanner is capable of moving along the second direction when the carrier is in the barcode scanning station; The second moving mechanism is used to drive the barcode scanner to move in the second direction when the carrier carrying the reagent card enters the barcode scanning station, so that the barcode scanner can scan and read the information codes on the reagent card in sequence.
[0009] As an optional implementation of this application, the scanning module further includes a reflective surface disposed in the workspace and capable of reflecting light. The reflective surface is configured such that when the carrier carrying the reagent card enters the scanning station, the information codes on the reagent card can be completely imaged on the reflective surface; the lens of the scanner faces the reflective surface to scan and read the information codes imaged on the reflective surface.
[0010] As an optional embodiment of this application, the reflective surface is inclined, and an angle α is formed between the reflective surface and the first direction, wherein the angle α is between 30° and 60°.
[0011] As an optional implementation of this application, the scanning module includes a reflector, the mirror surface of which constitutes the reflective surface; and / or the workspace is provided with a supplementary light source for providing supplementary light during scanning.
[0012] As an optional embodiment of this application, the reagent card is provided with at least two detection areas, which are configured such that when the reagent card is loaded onto the carrier, the at least two detection areas are arranged sequentially along a second direction; the second moving mechanism is further used to drive the detection module to move along the second direction to sequentially detect the detection areas on the reagent card when the carrier enters the detection station.
[0013] As an optional embodiment of this application, the second moving mechanism includes a slide that can move along a second direction, and the detection module and the barcode scanner are both mounted on the slide; and the barcode scanner is located to the side of the detection module so that an unobstructed light channel is formed between the barcode scanner and the reflective surface.
[0014] As an optional embodiment of this application, the first moving mechanism is a lead screw linear module; and / or the second moving mechanism is a gear and rack linear module.
[0015] As an optional embodiment of this application, the detection module includes a base, an excitation light source, and a receiving sensor. The base is driven to move along a second direction by a second moving mechanism. The excitation light source and the receiving sensor are both mounted on the base. During detection, the excitation light source irradiates the detection area of the reagent card to excite the fluorescent material in the detection area to radiate fluorescence. The intensity information of the radiated fluorescence is sensed by the receiving sensor.
[0016] As an optional embodiment of this application, the detection module further includes a sealing ring and a filter both mounted on the base; the filter is located on the input side of the receiving sensor and is pressed together by the sealing ring.
[0017] As an optional embodiment of this application, the analyzer further includes a first guiding mechanism for guiding the movement of the carrier in a first direction; and / or the analyzer further includes a second guiding mechanism for guiding the movement of the barcode scanner in a second direction.
[0018] Compared with the prior art, this application has the following advantages: In this application, by designing the barcode scanner to move along a second direction at the scanning station and setting a second moving mechanism, in conjunction with the arrangement of the information codes on the reagent card (i.e., arranged along the second direction), during scanning, the barcode scanner only needs to be driven to move along the second direction through the second moving mechanism. In this way, the barcode scanner can sequentially scan and read the information codes on the reagent card during the movement along the second direction, thereby realizing the reading of information from multiple information codes.
[0019] It should be understood that the description in this section is not intended to identify key or essential features of the embodiments of this application, nor is it intended to limit the scope of this application. Other features of this application will become readily apparent from the following description. Attached Figure Description
[0020] The above and other objects, features, and advantages of exemplary embodiments of this application will become readily apparent from the following detailed description taken in conjunction with the accompanying drawings. Several embodiments of this application are illustrated in the drawings by way of example and not limitation, in which: In the accompanying drawings, the same or corresponding reference numerals indicate the same or corresponding parts.
[0021] Figure 1 A schematic diagram of the structure of this application is shown; Figure 2 An exploded view of this application is shown; Figure 3A schematic diagram of the internal structure of this application is shown; Figure 4 A partial cross-sectional view of this application is shown; Figure 5 A schematic diagram of the connector portion of this application is shown; Figure 6 A schematic diagram of the structure of the carrier of this application is shown; Figure 7 A schematic diagram of the bottom structure of the carrier of this application is shown; Figure 8 A schematic diagram of the structure at the base of this application is shown.
[0022] Explanation of the labels in the diagram: L1, First direction; L2, Second direction; M, Reagent card; M1, QR code; M2, Detection area; 1. Main body; 10. Working space; 11. Upper shell; 12. Bottom shell; 13. Connecting base; 14. Display screen; 15. Printing module; 2. Carrier; 21. Cross-section; 22. Side positioning surface; 23. Top positioning surface; 24. Front positioning surface; 25. Elastic components; 3. First moving mechanism; 31. First motor; 32. Lead screw; 33. Lead nut; 4. First guide mechanism; 41. First slide rail; 42. First slide block; 5. Second moving mechanism; 51. Second motor; 52. Rack and pinion; 6. Second guide mechanism; 61. Second slide rail; 62. Second slide block; 7. Barcode scanning module; 71. Barcode scanner; 72. Reflector; 73. Supplemental lighting source; 8. Detection module; 81. Base; 811. First optical path channel; 812. Second optical path channel; 82. Excitation light source; 83. Receiving sensor; 84. Filter; 85. Sealing ring. Detailed Implementation
[0023] To make the objectives, features, and advantages of this application more apparent and understandable, the technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0024] Reference Figures 1-8As shown, this embodiment provides a multi-window fluorescence immunoassay analyzer (hereinafter referred to as the analyzer). This analyzer is applicable to reagent cards M with multiple detection zones M2, i.e., multi-part cards. Correspondingly, at least two information codes are formed on the reagent card M by means of brushing, printing or affixing. The information codes record the relevant information of the reagent card M, such as the reagent type, class name, etc. of each detection zone M2. The specific information can be entered according to actual needs.
[0025] The information code here can be a QR code, a barcode, or any other code that can be scanned to read information. No specific limitation is made here. For ease of understanding, this embodiment will use a QR code as an example for specific explanation.
[0026] The analyzer provided in this application mainly includes a body 1, a carrier 2, a first moving mechanism 3, a detection module 8, a barcode scanning module 7, and a second moving mechanism 5. The following is a detailed description of each component.
[0027] In this embodiment, as Figure 4 As shown, a working space 10 is formed inside the body 1; subsequent scanning and fluorescence detection are all carried out within this working space 10.
[0028] In some embodiments, the workspace 10 is specifically formed as follows: Figure 1 and Figure 2 As shown, the body 1 includes a bottom shell 12 and an upper shell 11, which together form the working space 10. Furthermore, a port for inserting a reagent card M is provided on the front side of the body 1, communicating with the working space 10. A connecting seat 13 is also fixedly connected within the working space 10.
[0029] In addition, in some embodiments, a display screen 14 is provided on the outer surface of the body 1, preferably on the top surface of the upper shell 11. The display screen 14 is preferably a touch screen. In this way, the display screen 14 can display some information during the detection process, and the user can also perform related operations by touch, such as controlling the detection module 8 to start, etc.
[0030] Of course, in some embodiments, this analyzer also includes a printing module 15, which prints out the detection and analysis results in paper form. The specific structure of the printing module can be referred to the printing structure in existing printers, and will not be described in detail here.
[0031] The carrier 2 is mainly used to load the reagent card M to be tested; the carrier 2 can move along the first direction L1 between the scanning station and the testing station in the workspace 10.
[0032] The scanning station refers to the station where the QR code M1 on the reagent card M is scanned. The detection station refers to the station where the fluorescence of the reagent card M is detected.
[0033] like Figure 1 As shown, the first direction L1 is the horizontal direction. In this embodiment, the first direction L1 can also be understood as the length direction of the body 1. For ease of explanation, the direction that is horizontal and perpendicular to the first direction L1 is denoted as the second direction L2. At this time, the second direction L2 can be understood as the width direction of the base.
[0034] like Figure 4 As shown, after the reagent card M is correctly loaded onto the carrier 2, the surface of the reagent card M is basically parallel to the first direction L1 and the second direction L2, that is, the surface of the reagent card M is basically horizontal.
[0035] In some embodiments, a specific carrier 2 is provided, such as Figure 6 As shown, a specific structure of the carrier 2 is illustrated. The carrier 2 mainly includes a horizontal cross surface 21. The cross surface 21 has two opposing side positioning surfaces 22 on both sides in the second direction L2. In addition, a front positioning surface 24 is provided at the front end of the cross surface 21. Both sides of the side positioning surfaces 22 are provided with a top positioning surface 23 extending inward. The carrier 2 is open on the side of the front positioning surface 24 in the second direction L2 as an insertion end, which corresponds to the insertion port of the body 1. During loading, the reagent card M is inserted into the carrier 2 through the insertion port and the insertion end.
[0036] In the loaded state, the front end of reagent card M abuts against the front positioning surface 24. In the second direction L3, reagent card M is basically positioned between the side positioning surfaces 22 on both sides. In the vertical direction, reagent card M is basically positioned between the top positioning surface 23 and the cross surface 21. Of course, in order to improve the clamping effect, in some other optional embodiments, one or more elastic members 25 that can vertically expand and contract relative to the cross surface 21 can be provided on the cross surface 21. After reagent card M is inserted into the carrier 2, the elastic member 25 can generate an upward elastic thrust on the bottom of reagent card M, so that reagent card M can be firmly abutted against the top positioning surface 23. Here, the elastic member 25 can be an elastic pin with a ball bearing structure at the top.
[0037] The first moving mechanism 3 is used to drive the carrier 2 to move along the first direction L1, so that the carrier 2 carrying the reagent card M to be tested moves between the testing station and the scanning station.
[0038] In some embodiments, the first moving mechanism 3 is preferably a lead screw linear module.
[0039] like Figure 7As shown, this embodiment provides a specific lead screw linear module, which includes a first motor 31, a lead screw 32, and a lead screw nut 33. The first motor 31 is fixed in the working space 10, for example, fixed on the connecting seat 13. The lead screw 32 extends along the first direction L1 and is rotatably connected to the bottom of the carrier 2. The lead screw nut 33 is threadedly connected to the lead screw 32 and fixed to the bottom of the carrier 2. The first motor 31 is used to drive the lead screw 32 to rotate. Thus, by driving the lead screw 32 to rotate through the first motor 31, the lead screw nut 33 and the carrier 2 as a whole move linearly along the first direction L1.
[0040] In addition, in order to guide the movement of the carrier 2 so that it can move stably along the first direction L1, in some embodiments, the analyzer further includes a first guide mechanism 4 for guiding the movement of the carrier 2 along the first direction L1.
[0041] In some embodiments, such as Figure 7 As shown, a specific first guiding mechanism 4 is provided, which mainly includes a first slide rail 41 and a first slide block 42 slidably connected to the first slide rail 41. The first slide rail 41 is fixed within the working space 10 and extends along the first direction L1, for example, fixed to the bottom wall of the connecting seat 13; while the first slide block 42 is fixed to the bottom of the carrier 2. Thus, guided by the first slide rail 41 and the first slide block 42, the carrier 2 can move stably along the first direction L1.
[0042] It is worth noting that in some existing analyzers, the carrier 2 is usually driven by a gear and rack transmission, which causes significant vibration during operation and thus makes the operation unstable.
[0043] Based on this, this embodiment uses a lead screw linear module to drive the carrier 2 to move along the first direction L1. Compared with the existing gear and rack transmission method, it has less vibration during operation and is therefore more stable.
[0044] The scanning module 7 is used to scan and read the QR code M1 on the reagent card M. The reagent card M has at least two QR codes M1. This embodiment shows the case where two QR codes M1 are set on one reagent card M.
[0045] In the reagent card M to which this application applies, the arrangement of its two QR codes M1 is limited such that, when the reagent card M is correctly mounted on the carrier 2, as shown... Figure 5 As shown, the two QR codes M1 are arranged side by side along the second direction L2, that is, they are on the same straight line parallel to the second direction L2.
[0046] Taking reagent card M as an example, each QR code M1 is arranged sequentially along the width of reagent card M.
[0047] like Figure 5 As shown, the scanning module 7 includes at least a scanner 71 capable of scanning and reading the QR code M1. The scanner 71 has been widely used and described in the prior art, so it will not be described in detail here.
[0048] The barcode scanner 71 is able to move along the second direction L2 when the carrier 2 is in the barcode scanning station, and its movement is mainly driven by the second moving mechanism 5.
[0049] The second moving mechanism 5 is used to drive the barcode scanner 71 to move along the second direction L2 when the carrier 2 carries the reagent card M into the barcode scanning station, so that the barcode scanner 71 can scan and read the QR code M1 on the reagent card M in sequence.
[0050] In some embodiments, such as Figure 6 As shown, the second moving mechanism 5 can be a rack and pinion linear module. Specifically, it includes a second motor 51 and a rack 52 with meshing teeth on the upper wall. The rack 52 extends along the second direction L2 and is fixed in the working space 10, for example, the rack 52 is fixed on the connecting seat 13. A gear that meshes with the rack 52 is fixed on the main shaft of the second motor 51. The second motor 51 drives the gear (not shown in the figure due to perspective) to rotate. Under the action of the rack 52, the second motor 51 and the gear as a whole can move along the second direction L2 on the rack 52.
[0051] In addition, such as Figure 6 As shown, the analyzer provided in this embodiment also includes a second guide mechanism 6. The second guide mechanism 6 mainly includes a second slide rail 61 and a second slide block 62 slidably connected to the second slide rail 61. The second slide rail 61 extends along the second direction L2 to be parallel to the rack 52, and the second slide rail 61 is fixed in the working space 10, for example, fixed on the connecting seat 13. The second motor 51 is fixed on the second slide block 62. When the second motor 51 drives the gear to rotate to move along the second direction L2, the second slide block 62 will move synchronously along the second direction L2.
[0052] The barcode scanner 71 and the detection module 8 are both mounted on the second slide 62 and are driven by the second slide 62 to move along the second direction L2.
[0053] It is worth noting that, such as Figure 6 As shown, the barcode scanner 71 is located to the side of the detection module 8 so that an unobstructed light channel is formed between the barcode scanner 71 and the reflective surface, that is, the presence of the detection module 8 will not obstruct the scanning path of the barcode scanner 71.
[0054] After the carrier 2 is correctly loaded onto the carrier 2, when scanning is required, the first moving mechanism 3 drives the carrier 2 to move along the first direction L1 to the scanning station; then, the scanner 71 is turned on, and the second moving mechanism 5 drives the scanner 71 to move along the second direction L2. During this process, the scanner 71 can scan the QR code M1 on the reagent card M in sequence to read the information of the QR code M1.
[0055] This method allows for the scanning of multiple QR codes M1 on a single reagent card M.
[0056] In addition, in order to prevent the overall size of the analyzer from being too large, especially the height, some embodiments provide a specific barcode scanning module 7, which uses a mirror reflection method for barcode scanning.
[0057] Specifically, in combination Figure 4 and Figure 5 As shown, the scanning module 7 also includes a reflective surface disposed within the working space 10 and capable of reflecting light. For example, the scanning module 7 includes a reflector 72, one of the mirror surfaces of the reflector 72 serving as the reflective surface.
[0058] The reflective surface is configured such that when the carrier 2, carrying the reagent card M, enters the scanning station, the QR code M1 on the reagent card M can be completely imaged on the reflective surface; the lens of the scanner 71 faces the reflective surface to scan and read the QR code M1 imaged on the reflective surface.
[0059] As a specific implementation method, such as Figure 4 As shown, the reflective surface forms an angle α with the first direction L1, the angle α being between 30° and 60°, preferably 45°.
[0060] When carrier 2 carries reagent card M into the scanning station, all QR codes M1 on reagent card M are located below reflector 72 and are imaged in reflector 72. The lens of scanner 71 is not directly facing the QR codes M1 on reagent card M, but facing the mirror. Scanner 71 scans the QR codes M1 imaged on reflector 72. In this way, scanner 71 can scan QR codes M1 during movement.
[0061] In simple terms, the QR code M1 on the reagent card M is reflected by the reflector 72 and projected onto the lens of the scanner 71, where it is scanned and received. The light reflection path can be roughly described as follows: Figure 4 The path shown in L3.
[0062] As can be seen, in this embodiment, the barcode scanner 71 does not directly scan the QR code M1 on the reagent card M, but scans the QR code M1 by reflecting it through the mirror 72. This setting makes the whole device more compact and does not increase the height of the analyzer too much.
[0063] Additionally, due to the dim lighting in the workspace 10, in order for the barcode scanner 71 to scan clearly, in some embodiments, such as... Figure 4 As shown, the workspace 10 is provided with a supplementary light source 73 for supplementary lighting during barcode scanning. For example, a supplementary light is provided and installed on the inner top of the upper shell 11.
[0064] The detection module 8 provided in this embodiment is mainly used to perform fluorescence detection on the reagent card M carried by the carrier 2 into the detection station.
[0065] This embodiment provides a specific detection module 8, such as Figure 3 and Figure 4 As shown, the detection module 8 includes a base 81, an excitation light source 82 (e.g., an excitation lamp), and a receiving sensor 83. The base 81 is driven by the second moving mechanism 5 to move along the second direction L2, that is, the base 81 is fixed on the second slide 62.
[0066] Both the excitation light source 82 and the receiving sensor 83 are mounted on the base 81. During detection, the excitation light source 82 irradiates the detection area M2 of the reagent card M to excite the fluorescent material in the detection area M2 to emit fluorescence. The intensity information of the emitted fluorescence is sensed by the receiving sensor 83.
[0067] In addition, in some embodiments, the detection module 8 further includes a sealing ring 85 and a filter 84 both mounted on the base 81; the filter 84 is disposed on the input side of the receiving sensor 83 and is pressed by the sealing ring 85.
[0068] Specifically, such as Figure 4 As shown, the sealing ring 85 has a ring-shaped structure and is basically nested around the receiving sensor 83. The base 81 has a mounting groove for mounting the filter 84. The filter 84 is embedded in the mounting groove. The inner edge of the sealing ring 85 extends to the outer peripheral area of the end side of the filter 84 to press the filter 84 tightly in the mounting groove. The function of the sealing ring 85 is twofold: first, to press and fix the filter 84; and second, under the seal of the sealing ring 85, a sealed space can be formed between the filter 84 and the receiving sensor 83 to prevent dust from entering the sealed space.
[0069] Specifically, a first optical path channel 811 is provided in the base 81 corresponding to the position of the excitation light source 82, and a second optical path channel 812 is provided in the base 81 corresponding to the position of the receiving sensor 83.
[0070] During detection, the base 81 moves to the detection area M2 of the reagent card M, where the excitation light source 82 emits light, which is then directed to the detection area M2 through the first optical path channel 811 to excite the fluorescent substance in the detection area M2 to emit fluorescence. The emitted fluorescence is then directed to the receiving sensor 83 through the second optical path channel 812, where the receiving sensor 83 senses and detects the intensity information of the fluorescence and performs analysis accordingly. For example, the concentration information of the substance to be detected can be obtained based on the fluorescence intensity information.
[0071] In order to accommodate the detection of multi-part reagent cards M (i.e., multi-part cards), in this embodiment, the second moving mechanism 5 is also configured to drive the detection module 8 to move along the second direction L2 when the carrier 2 enters the detection station so as to sequentially detect the detection area M2 on the reagent card M.
[0072] like Figure 5 As shown, the multi-card in this embodiment is constructed such that the reagent card M has at least two detection areas M2. For example, this embodiment shows a case with three detection areas M2. The distribution of each detection area M2 is such that when the reagent card M is loaded onto the carrier 2, each detection area M2 is arranged sequentially along the second direction L2. It can also be understood that each detection area M2 is arranged side by side along the width direction of the reagent card M.
[0073] In this specific embodiment, both the detection module 8 and the barcode scanner 71 are mounted on the second slide 62 of the second moving mechanism 5. Specifically, the base 81 of the detection module 8 is fixed on the second slide 62, and the barcode scanner 71 is directly fixed on the second slide 62 or fixed on the base 81. In addition, some related circuit boards in the detection module 8 are fixed on the base 81 and / or the second slide 62.
[0074] As the second slide 62 moves along the second direction L2, it can drive the entire detection module 8 and the barcode scanner 71 to move synchronously along the second direction L2, so as to achieve continuous barcode scanning or sequential detection of multiple detection areas M2.
[0075] Taking the detection of multiple detection areas M2 as an example, the first moving mechanism 3 first moves the carrier 2, which is correctly loaded with reagent card M, along the first direction L1 to the detection station. Then, the second moving mechanism 5 drives the detection module 8 to move to the first detection area M2 of the first reagent card M for one detection. After the detection of the first detection area M2 is completed, the second moving mechanism 5 continues to drive the detection module 8 along the second direction L2 to the next detection area M2 for detection. This process is repeated to achieve the detection of multiple detection areas M2.
[0076] It should be understood that the various forms of processes shown above can be used to rearrange, add, or delete steps. For example, the steps described in this application can be executed in parallel, sequentially, or in different orders, as long as the desired result of the technical solution disclosed in this application can be achieved, and this is not limited herein.
[0077] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "a plurality of" means two or more, unless otherwise explicitly specified.
[0078] The above description is merely a specific embodiment of this application, but the scope of protection of this application is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in this application should be included within the scope of protection of this application. Therefore, the scope of protection of this application should be determined by the scope of the claims.
Claims
1. A multi-window fluorescence immunoassay analyzer, characterized in that, include: The body, within which a working space is formed; A carrier for loading the reagent card to be tested; the carrier is capable of moving along a first direction within the workspace between the barcode scanning station and the testing station; A first moving mechanism is used to drive the carrier to move along a first direction; The detection module is used to perform fluorescence detection on the reagent cards that are carried into the detection station by the carrier. A barcode scanning module is used to scan and read information codes on a reagent card, wherein the reagent card has at least two information codes, and when the reagent card is loaded on a carrier, the at least two information codes are arranged sequentially along a second direction, the second direction being perpendicular to the first direction; the barcode scanning module includes at least a barcode scanner capable of scanning and reading the information codes; the barcode scanner is capable of moving along the second direction when the carrier is in the barcode scanning station; The second moving mechanism is used to drive the barcode scanner to move in the second direction when the carrier carrying the reagent card enters the barcode scanning station, so that the barcode scanner can scan and read the information codes on the reagent card in sequence.
2. The multi-window fluorescence immunoassay analyzer according to claim 1, characterized in that, The scanning module also includes a reflective surface located in the workspace that can reflect light. The reflective surface is configured such that when the carrier carrying the reagent card enters the scanning station, the information code on the reagent card can be completely imaged on the reflective surface. The scanner's lens faces the reflective surface to scan and read the information code imaged on the reflective surface.
3. The multi-window fluorescence immunoassay analyzer according to claim 2, characterized in that, The reflective surface is inclined, and an angle α is formed between the reflective surface and the first direction, the angle α being between 30° and 60°.
4. The multi-window fluorescence immunoassay analyzer according to claim 2, characterized in that, The scanning module includes a reflector, the mirror surface of which constitutes the reflective surface; and / or the workspace is provided with a supplementary light source for providing supplementary light during scanning.
5. The multi-window fluorescence immunoassay analyzer according to claim 1, characterized in that, The reagent card has at least two detection areas, which are configured such that when the reagent card is loaded onto the carrier, the at least two detection areas are arranged sequentially along a second direction; the second moving mechanism is also used to drive the detection module to move along the second direction to sequentially detect the detection areas on the reagent card when the carrier enters the detection station.
6. The multi-window fluorescence immunoassay analyzer according to claim 1, characterized in that, The second moving mechanism includes a slide that can move along a second direction, and the detection module and the barcode scanner are both mounted on the slide; and the barcode scanner is located to the side of the detection module so that an unobstructed light channel is formed between the barcode scanner and the reflective surface.
7. The multi-window fluorescence immunoassay analyzer according to any one of claims 1-6, characterized in that, The first moving mechanism is a lead screw linear module; and / or the second moving mechanism is a gear and rack linear module.
8. The multi-window fluorescence immunoassay analyzer according to any one of claims 1-6, characterized in that, The detection module includes a base, an excitation light source, and a receiving sensor. The base is driven to move along a second direction by a second moving mechanism. The excitation light source and the receiving sensor are both mounted on the base. During detection, the excitation light source irradiates the detection area of the reagent card to excite the fluorescent material in the detection area to emit fluorescence. The intensity information of the emitted fluorescence is sensed by the receiving sensor.
9. The multi-window fluorescence immunoassay analyzer according to claim 8, characterized in that, The detection module also includes a sealing ring and a filter, both mounted on the base; the filter is located on the input side of the receiving sensor and is pressed together by the sealing ring.
10. The multi-window fluorescence immunoassay analyzer according to claim 1, characterized in that, The analyzer further includes a first guiding mechanism for guiding the movement of the carrier in a first direction; and / or the analyzer further includes a second guiding mechanism for guiding the movement of the barcode scanner in a second direction.
Citation Information
Patent Citations
Handheld fluorescence immunoassay analyzer
CN222280475U