A membrane separation apparatus for active biological enzymes

Abstract

The utility model discloses a membrane separation equipment for active bioenzyme, including membrane separator, the membrane separator outside wall fixedly connected with temperature control ring, the temperature control ring inside is established with heating chamber, the heating chamber inside is provided with heating assembly, the heating assembly is away from the one side of membrane separator central and is provided with separation mechanism, the temperature control ring outside is provided with liquid injection pipe spare. The utility model discloses through the cooperation of heating assembly, separation mechanism and liquid injection pipe spare, has realized the efficient, even heating and cooling control of membrane separator. Thus effectively solved the problem that active bioenzyme is sensitive to temperature in the membrane separation process, needs accurate temperature control, can provide stable heating insulation when needing, can also realize rapid cooling, has kept the activity of bioenzyme to the maximum, has improved the efficiency of separation process and product quality.

Description

Technical Field

[0001] This utility model relates to the field of membrane separation equipment technology, specifically to a membrane separation device for active biological enzymes. Background Technology

[0002] Membrane separation technology is one of the key methods in the separation, purification, and concentration of active biological enzymes. However, as proteins with catalytic activity, biological enzymes are extremely sensitive to temperature. Excessively high or low temperatures can lead to enzyme denaturation and inactivation, thus seriously affecting separation efficiency and the quality of the final product.

[0003] Currently, most common temperature control methods for membrane separation equipment employ external jacketed heat exchange structures. These structures typically introduce heating or cooling media into the jacket, where they indirectly exchange heat with the membrane separator through the jacket wall. This method has significant limitations: First, due to the fixed gap between the jacket and the vessel wall or poor medium flow, the heat exchange efficiency is low, the temperature response is sluggish, and it is difficult to achieve rapid heating and cooling switching. Second, in order to achieve heating and cooling functions, two independent pipelines and control systems are often required, which makes the equipment structure complex, bulky, and costly. Third, traditional heating methods, such as externally wrapped heating tape, are prone to uneven heating of the outer wall of the membrane separator, generating local hot spots, which can damage temperature-sensitive active biological enzymes.

[0004] Therefore, we propose to design a membrane separation device for active biological enzymes. Utility Model Content

[0005] The purpose of this section is to outline some aspects of the embodiments of this utility model and to briefly introduce some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of this application, to avoid obscuring the purpose of these documents; however, such simplifications or omissions should not be used to limit the scope of this utility model.

[0006] To solve the above-mentioned technical problems, according to one aspect of the present invention, the present invention provides the following technical solution: A membrane separation device for active biological enzymes includes a membrane separator, a temperature control ring fixedly connected to the outer wall of the membrane separator, a heating chamber inside the temperature control ring, a heating component inside the heating chamber, a separation mechanism on the side of the heating component away from the center of the membrane separator, and a liquid injection pipe outside the temperature control ring.

[0007] In a preferred embodiment of the membrane separation device for active biological enzymes described in this utility model, the heating component includes an arc-shaped heating box with a heating wire embedded and fixedly connected inside. The heating box fits snugly against the outer wall surface of the membrane separator. During heating, the heating box perfectly conforms to the outer wall of the membrane separator, thus facilitating temperature adjustment at corresponding locations within the membrane separator.

[0008] In a preferred embodiment of the membrane separation device for active biological enzymes described in this utility model, the heating wires are evenly distributed in the heating box, and the heating box is filled with heat-conducting oil to facilitate the uniform application of the heat from the heating wires to the outer wall of the heating box, thereby ensuring uniform heating of the outer wall of the membrane separator.

[0009] In a preferred embodiment of the membrane separation device for active biological enzymes described in this utility model, the top and bottom of the heating box are smoothly fitted to the top and bottom of the heating chamber, respectively.

[0010] In a preferred embodiment of the membrane separation device for active biological enzymes described in this utility model, the separation mechanism includes a separation box fixed to the outer wall of a temperature control ring. A movable rod is slidably connected inside the separation box. An electromagnet is embedded and fixedly connected to the outer end of the separation box. A magnet is fixedly connected to the end of the movable rod. A spring assembly is fixedly connected between the magnet and the separation box. When the electromagnet is energized, it generates magnetic force, which repels the magnetic poles of the magnet, facilitating the movement of the movable rod into the temperature control ring.

[0011] As a preferred embodiment of the membrane separation device for active biological enzymes described in this utility model, the inner wall of the temperature control ring is uniformly distributed with supports, and the supports have connection holes in the middle, through which liquid injected into the temperature control ring can flow during cooling.

[0012] In a preferred embodiment of the membrane separation device for active biological enzymes described in this utility model, the liquid injection fitting includes an inlet pipe fixed to the bottom of the temperature control ring and a drain pipe fixed to the top of the temperature control ring, with the inlet pipe and drain pipe corresponding to different heating chambers. Cold medium is injected through the inlet pipe and gradually flows into another heating chamber through the connection hole, finally being discharged through the drain pipe, facilitating rapid cooling of the membrane separator.

[0013] Compared with the prior art, the beneficial effects of this utility model are: This invention achieves efficient and uniform heating and cooling control of the membrane separator through the coordinated operation of the heating component, separation mechanism, and liquid injection pipe. This effectively solves the problem of active bioenzymes being sensitive to temperature and requiring precise temperature control during membrane separation. It provides stable heating and insulation when needed, and also enables rapid cooling, maximizing the preservation of bioenzyme activity and improving the efficiency of the separation process and product quality. Attached Figure Description

[0014] To more clearly illustrate the technical solutions of the embodiments of this utility model, the present utility model will be described in detail below with reference to the accompanying drawings and detailed embodiments. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Among them: Figure 1 This is a perspective view of a membrane separation device for active biological enzymes according to the present invention; Figure 2 This is a schematic diagram of the cross-sectional structure of a temperature control ring for a membrane separation device for active biological enzymes according to the present invention. Figure 3 This is a schematic diagram of a heating component for a membrane separation device for active biological enzymes according to the present invention; Figure 4 This is a schematic diagram of the separation mechanism of a membrane separation device for active biological enzymes according to the present invention.

[0015] Legend: 1. Membrane separator; 2. Temperature control ring; 201. Support; 202. Connection hole; 3. Heating chamber; 4. Heating assembly; 401. Heating box; 402. Heating wire; 403. Heat transfer oil; 5. Separation mechanism; 501. Separation box; 502. Movable rod; 503. Electromagnet; 504. Magnetic plate; 505. Spring assembly; 6. Inlet pipe; 7. Drain pipe. Detailed Implementation

[0016] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be further described in detail below with reference to the accompanying drawings.

[0017] Secondly, this utility model is described in detail with reference to the schematic diagrams. When describing the embodiments of this utility model, for ease of explanation, the cross-sectional views showing the device structure may be partially enlarged, not according to the usual scale. Furthermore, the schematic diagrams are merely examples and should not limit the scope of protection of this utility model. In addition, in actual manufacturing, the three-dimensional spatial dimensions of length, width, and depth should be included.

[0018] Please see Figure 1-4This utility model provides a membrane separation device for active biological enzymes, including a membrane separator 1, a temperature control ring 2 fixedly connected to the outer wall of the membrane separator 1, a heating chamber 3 opened inside the temperature control ring 2, and a heating component 4 arranged inside the heating chamber 3.

[0019] The heating assembly 4 includes an arc-shaped heating box 401, in which a heating wire 402 is embedded and fixedly connected. The heating box 401 fits into the outer wall surface of the membrane separator 1. When heating, the heating box 401 can perfectly fit into the outer wall of the membrane separator 1, thereby facilitating temperature adjustment at corresponding positions in the membrane separator 1.

[0020] In this embodiment, the heating wire 402 is evenly distributed in the heating box 401, and the heating box 401 is filled with heat-conducting oil 403, so that the heat of the heating wire 402 can be evenly applied to the outer wall of the heating box 401, thereby making the outer wall of the membrane separator 1 evenly heated.

[0021] In this embodiment, the top and bottom of the heating box 401 are smoothly attached to the top and bottom of the heating cavity 3, respectively, and can move stably when driven by the subsequent separation mechanism 5.

[0022] A separation mechanism 5 is provided on the side of the heating component 4 away from the center of the membrane separator 1; The separation mechanism 5 includes a separation box 501 fixed to the outer wall of the temperature control ring 2. A movable rod 502 is slidably connected inside the separation box 501. An electromagnet 503 is embedded and fixedly connected to the outer end of the separation box 501. A magnet 504 is fixedly connected to the end of the movable rod 502. A spring assembly 505 is fixedly connected between the magnet 504 and the separation box 501. When the electromagnet 503 is energized, it generates magnetic force, which repels the magnetic poles of the magnet 504, facilitating the movement of the movable rod 502 into the temperature control ring 2.

[0023] The temperature control ring 2 is externally equipped with a liquid injection pipe, which includes an inlet pipe 6 fixed to the bottom of the temperature control ring 2 and a drain pipe 7 fixed to the top of the temperature control ring 2. The inlet pipe 6 and the drain pipe 7 correspond to different heating chambers 3. Cold medium is injected through the inlet pipe 6 and can gradually flow into other heating chambers 3 through the connection hole 202, and finally discharged through the drain pipe 7, which facilitates rapid cooling of the membrane separator 1.

[0024] In this embodiment, the inner wall of the temperature control ring 2 is uniformly distributed with brackets 201, and the brackets 201 have connecting holes 202 in the middle. The liquid injected into the temperature control ring 2 can flow through each connecting hole 202 when cooling.

[0025] Working principle: When the membrane separation process requires heating or maintaining a certain temperature: First, the separation mechanism 5 is activated by energizing the electromagnet 503, causing it to generate the same magnetic poles as the magnet 504. Based on the principle of like poles repelling each other, the electromagnet 503 generates a repulsive force on the magnet 504. This repulsive force overcomes the elastic force of the spring assembly 505, pushing the movable rod 502 towards the center of the temperature control ring 2. Since the end of the movable rod 502 is connected to the heating box 401, the heating box 401 is pushed to fit tightly against the outer wall of the membrane separator 1.

[0026] Subsequently, the heating assembly 4 is activated, energizing the heating wire 402 to generate heat, which is then conducted to the heat-conducting oil 403 filling the heating box 401. Due to the excellent thermal conductivity and temperature uniformity of the heat-conducting oil, and the even distribution of the heating wire 402 within the heating box, heat can be evenly transferred through the wall of the heating box 401 to the outer wall of the membrane separator 1, which is tightly fitted to it. This provides uniform and stable heating to the interior of the membrane separator 1, creating a suitable temperature environment for the active biological enzymes and preventing localized overheating that could lead to enzyme inactivation.

[0027] When it is necessary to quickly reduce the temperature of membrane separator 1, firstly, the separation mechanism 5 is controlled to de-energize the electromagnet 503. Through the elastic force of the spring assembly 505, the movable rod 502 is driven to move away from the center of the temperature control ring 2, causing the heating box 401 to detach from the surface of the membrane separator 1. In specific design, the spring assembly 505 with sufficient elastic force needs to be set according to the weight of the heating box 401.

[0028] Subsequently, a cooling medium, such as coolant, is injected into the heating chamber 3 inside the temperature control ring 2 through the injection pipe. The cooling medium enters the corresponding heating chamber 3 from the inlet pipe 6, and under pressure, flows into the adjacent heating chamber 3 through the connection hole 202 on the bracket 201, and is finally discharged from the drain pipe 7.

[0029] During this process, the cooling medium directly or indirectly washes the outer wall of the membrane separator 1 and flows through the channel formed after being pushed open, quickly carrying away the heat generated or that needs to be dissipated during the operation of the membrane separator 1, thereby achieving rapid and uniform cooling.

[0030] In practical use, the heating temperature can be precisely adjusted by controlling the power of the heating wire 402. The cooling rate and final temperature can be precisely controlled by controlling the flow rate and temperature of the cooling medium. The switching between heating and cooling modes is mainly controlled by turning the electromagnet 503 in the separation mechanism 5 on and off to control the bonding and separation state of the heating box 401, which is simple to operate and responds quickly.

[0031] Although the present invention has been described above with reference to embodiments, various modifications can be made and components can be replaced with equivalents without departing from the scope of the present invention. In particular, as long as there is no structural conflict, the features in the embodiments disclosed in this invention can be combined with each other in any way. The lack of an exhaustive description of these combinations in this specification is merely for the sake of brevity and resource conservation. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A membrane separation device for active biological enzymes, comprising a membrane separator (1), characterized in that, A temperature control ring (2) is fixedly connected to the outer wall of the membrane separator (1). A heating chamber (3) is opened inside the temperature control ring (2). A heating component (4) is installed inside the heating chamber (3). A separation mechanism (5) is installed on the side of the heating component (4) away from the center of the membrane separator (1). An injection pipe is installed outside the temperature control ring (2).

2. The membrane separation device for active biological enzymes according to claim 1, characterized in that, The heating assembly (4) includes an arc-shaped heating box (401), in which an electric heating wire (402) is embedded and fixedly connected, and the heating box (401) fits against the outer wall surface of the membrane separator (1).

3. The membrane separation device for active biological enzymes according to claim 2, characterized in that, The heating wire (402) is evenly distributed in the heating box (401), and the heating box (401) is filled with heat-conducting oil (403).

4. The membrane separation device for active biological enzymes according to claim 2, characterized in that, The top and bottom of the heating box (401) are smoothly fitted to the top and bottom of the heating cavity (3), respectively.

5. A membrane separation device for active biological enzymes according to claim 1, characterized in that, The separation mechanism (5) includes a separation box (501) fixed to the outer wall of the temperature control ring (2). A movable rod (502) is slidably connected inside the separation box (501). An electromagnet (503) is embedded and fixedly connected to the outer end of the separation box (501). A magnet (504) is fixedly connected to the end of the movable rod (502). A spring assembly (505) is fixedly connected between the magnet (504) and the separation box (501).

6. The membrane separation device for active biological enzymes according to claim 1, characterized in that, The inner wall of the temperature control ring (2) is evenly distributed with brackets (201), and a connecting hole (202) is opened in the middle of the brackets (201).

7. The membrane separation device for active biological enzymes according to claim 1, characterized in that, The liquid injection fitting includes an inlet pipe (6) fixed to the bottom of the temperature control ring (2) and a drain pipe (7) fixed to the top of the temperature control ring (2). The inlet pipe (6) and the drain pipe (7) correspond to different heating chambers (3).

Images