CRYSTALLINE FORM OF LORLATINIB FREE BASE

CY1126565T1Undetermined Publication Date: 2026-07-31PFIZER INC
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Patent Information

Application Number
CY20241100044T
Authority / Receiving Office
CY · CY
Patent Type
Patents
Current Assignee / Owner
Priority Date
2016-06-20
Filing Date
2024-01-23
Publication Date
2026-07-31
Estimated Expiration
2044-01-23
Patent Text Reader

Abstract

The present invention relates to a pharmaceutical composition comprising a crystalline form of the free base of (10R-7-amino-12-fluoro-2,10,16-trimethyl-5-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecayne-3-carbonitrile (lorlatinib), and to methods of using such compositions in the treatment of pathological cell growth, such as cancer, in a mammal.
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