Bone necrosis repair stent with osteoblast implantation function

Abstract

Bone necrosis repair stent with osteoblast implantation function, comprising a metal stent (1), wherein extension blocks (3) are rigidly connected to the outside of the metal stent (1), and the metal stents (1) are pivotally connected to telescopic rods (4) via the extension blocks (3), support blocks (6) are arranged on the metal stent (1), wherein damping pivot axes (12) are rigidly connected to the top of the support blocks (6), and the top of the support blocks (6) are rotatably connected to sleeves (7) via the damping pivot axes (12), wherein fluid outlet openings (11) are formed on the surface of the sleeves (7), and the inside of the sleeves (7) is in contact with inner tubes (5), wherein through holes (16) are provided on the outside of the inner tubes (5), and piston rods (9) are movably inserted through one end of the inner tubes (5), wherein at one end of the piston rods (9) a sealing plug (17) is firmly attached,wherein the edge of the sealing plug (17) is in contact with the inner wall of the inner tubes (5), push plates are firmly connected at the other end of the piston rods (9) and limiting components are arranged on the outside of the sleeves (7).

Description

[0001] The present invention relates to the technical field of medical devices, in particular a bone necrosis repair stent with osteoblast implantation function.

[0002] In the early stages of osteonecrosis, bone strength decreases in the necrotic region. Implantation of a repair stent can effectively distribute body weight and transfer the load from the necrotic area to the surrounding healthy bone tissue, thus preventing femoral head collapse under stress. Furthermore, the repair stent helps maintain the original shape and structure of the bone and can also serve as a delivery system for the controlled release of medication.

[0003] If the bone necrosis is limited to a small area and it can be ensured that no tumor cells remain in the vicinity of the necrotic region or that there is no risk of recurrence, the entire bone does not need to be removed. Instead, treatment can consist of local debridement, removal of dead bone tissue, and bone repair. For example, in the case of localized bone infarction, dead bone fragments can be removed using minimally invasive surgery, and bone regeneration can then be promoted using methods such as bone marrow stem cell transplantation.

[0004] Some emerging treatment methods for osteonecrosis combine repair stents with stem cell therapy. Stem cells can be implanted onto the stent material and then deployed along with the stent into the necrotic region. The stent provides the stem cells with a favorable environment for survival and differentiation, and the stem cells differentiate into osteoblasts under the guidance of the stent, thereby promoting bone regeneration. This combined therapy promises improved efficacy in the treatment of osteonecrosis.

[0005] When repairing bone defects using existing techniques, the problem lies in the difficulty of controlling the implantation position of the stem cells. Ideally, the stem cells should be distributed both at the edges and within the bone defect to promote the growth of new bone in the damaged area. If the stem cells accumulate in non-critical areas... - As at the interface between the stent material and the surrounding healthy tissue - the bone defect cannot be effectively filled. Therefore, a bone necrosis repair stent with osteoblast implantation function is proposed to solve the aforementioned problem.

[0006] To compensate for the aforementioned shortcomings, the present invention provides a bone necrosis repair stent with osteoblast implantation function, which aims to improve the problem in the existing technique that the implantation position of the transplanted stem cells is difficult to regulate.

[0007] To achieve the above objective, the present invention employs the following technical solutions: a bone necrosis repair stent with osteoblast implantation function, comprising a metal stent, wherein extension blocks are rigidly connected to the outside of the metal stent, wherein the metal stents are pivotally connected to telescopic rods via the extension blocks, support blocks are arranged on the metal stent, wherein damping pivot axes are rigidly connected to the top of the support blocks, and the top of the support blocks is rotatably connected to sleeves via the damping pivot axes, wherein fluid outlet openings are formed on the surface of the sleeves, and the inside of the sleeves is in contact with inner tubes, wherein through-holes are provided on the outside of the inner tubes, piston rods are movably inserted through one end of the inner tubes, and a sealing plug is rigidly connected to one end of the piston rods.wherein the edge of the sealing plug is in contact with the inner wall of the inner tubes, push plates are firmly connected at the other end of the piston rods, and limiting components are arranged on the outside of the sleeves.

[0008] As a further description of the above technical solution, the limiting component comprises a housing attached to the outside of the sleeve, wherein a movement rod is movably inserted through the top of the housing, wherein a button is attached to the tip of the movement rod, and positioning grooves are provided on the outer wall of the inner tube.

[0009] As a further description of the above technical solution, a removable component is arranged on the metal stent, wherein the removable component comprises a screw rod which is attached to the underside of the support block, wherein a threaded hole is provided on the top of the metal stent, wherein the surface of the screw rod is screwed to the inside of the threaded hole.

[0010] As a further description of the above technical solution, the number of positioning grooves is three, wherein the three positioning grooves have the same hole diameter and are arranged symmetrically at equal intervals, and wherein the lower ends of the movement rods each interact appropriately with the three positioning grooves.

[0011] As a further description of the above technical solution, a nut is screwed onto the surface of the screw rod, with the nut resting against the side facing the metal stent. There are several threaded holes, arranged symmetrically in a ring at equal intervals.

[0012] As a further description of the above technical solution, the number of liquid outlet openings is three, with the three liquid outlet openings having the same hole diameter and being arranged symmetrically at equal intervals. The through-holes provided on the outer wall of the sleeve interact appropriately with the three liquid outlet openings.

[0013] As a further description of the above technical solution, a limiting ring is firmly attached to the surface of the moving rod, with the edge of the limiting ring being in contact with the inner wall of the housing and being slidably connected.

[0014] As a further description of the above technical solution, a spring is attached to the surface of the moving rod, with one end of the spring being fixedly connected to the top of the limiting ring, the other end being fixedly connected to the inner wall of the housing, and the lower end of the moving rod movably penetrating the outer surface of the sleeve and bearing against the outer surface of the inner tube.

[0015] As a further description of the above technical solution, a threaded groove is provided at one end of the sleeve, with the wall of the threaded groove being screwed to the screw.

[0016] The utility model has the following beneficial effects: 1. In the present invention, the provided metal stent is placed in the cleaned bone defect to provide uniform support. Using syringe principles, the cell suspension is injected into the interior of the metal stent. This method allows for more precise delivery of the cells to specific positions. By adjusting the overlap position between the through-holes and the fluid outlet openings according to the required placement of the bone cells, the implantation position for the osteoblasts can be regulated. 2. In the present invention, the sleeve and screw can be adjusted to different locations by tightening the screw rod in threaded holes at different positions, thereby improving flexibility in the repair of necrotic bone. The use of a detachable connection facilitates the assembly and disassembly of the upper sleeve and the screw. 3. In the present invention, the inner tube can be limited under the vertical elastic potential energy of the spring by pressing the lower end of the moving rod against the positioning groove formed on the outer surface of the inner tube. This ensures the fixation effect after the positions of the through-holes and the fluid outlet openings have overlapped, and guarantees the continuity of the osteoblast implantation. Fig. Figure 1 shows a main view of a bone necrosis repair stent with osteoblast implantation function according to the present invention. Fig. Figure 2 shows a schematic representation of the support block, the damping axis of rotation, the sleeve, the inner tube and the piston rod of a bone necrosis repair stent with osteoblast implantation function according to the present invention. Fig. Figure 3 shows a schematic exploded view of the sleeve, inner tube, piston rod and sealing plug of a bone necrosis repair stent with osteoblast implantation function according to the present invention. Fig. Figure 4 shows a schematic sectional view of the support block, the damping axis of rotation, the sleeve, the inner tube and the piston rod of a bone necrosis repair stent with osteoblast implantation function according to the present invention. Fig. Figure 5 shows an enlarged view of area A of a bone necrosis repair stent with osteoblast implantation function according to the present invention.

[0017] As in Fig. 1, Fig. 2 to Fig. Figure 3 shows an embodiment of the bone necrosis repair stent with osteoblast implantation function provided by the present invention, comprising a metal stent 1, wherein extension blocks 3 are rigidly connected to the outside of the metal stent 1. Telescopic rods 4 are pivotally connected between the metal stents 1 via the extension blocks 3, so that the center of the metal stent 1 can adjust its length via the pivotally connected telescopic rods 4. A support block 6 is arranged on the metal stent 1, a damping pivot 12 is rigidly connected to the upper side of the support block 6, and the upper side of the support block 6 is rotatably connected to a sleeve 7 via the damping pivot 12. The rotation of the sleeve 7 is effected by the damping pivot 12, and the fixing effect after rotation is achieved by frictional damping. A threaded groove is provided at one end of the sleeve 7, the wall of which is screwed to it with a screw 8.The screw 8 serves to firmly connect the bone to the metal stent 1 by screwing the screw 8 into the bone tissue. Fluid outlet openings 11 are formed on the surface of the sleeve 7, through which osteoblasts can be transported more precisely to specific positions. The inside of the sleeve 7 is in contact with an inner tube 5, and through-holes 16 are formed on the outer surface of the inner tube 5. If the through-holes 16 formed on the outer wall of the inner tube 5 align with the fluid outlet openings 11, this facilitates the injection of osteoblasts into the interior of the inner tube 5. A piston rod 9 is movably pierced and connected at one end of the inner tube 5. A sealing plug 17 is fixedly connected to one end of the piston rod 9, the edges of which are in contact with the inner wall of the inner tube 5.The piston rod 9 and the sealing plug 17 move along the inner wall of the inner tube 5, and the cell suspension is injected into the interior of the metal stent 1 using a syringe principle. This method allows for more precise delivery of the cells to specific positions. A push plate is fixed to the other end of the piston rod 9, facilitating its movement. There are three fluid outlet openings 11, all of which have the same diameter and are symmetrically spaced at equal intervals. The through-holes 16 formed in the outer wall of the sleeve 7 are each aligned with the three fluid outlet openings 11. This allows the overlap between the through-holes 16 and the fluid outlet openings 11 to be adjusted according to the required implantation position of the bone cells.A limiting component is arranged on the outside of sleeve 7.

[0018] As in Fig. 4 and Fig. As shown in Figure 5, the limiting component comprises a housing 13 that is attached to the outside of the sleeve 7. A movement rod 18 is movably pierced and connected to the top of the housing 13, and a button 19 is fixedly attached to the end of the movement rod 18. This facilitates vertical movement of the button 19 by medical personnel by pulling it. Positioning grooves 10 are arranged on the outer wall of the inner tube 5. There are three positioning grooves 10, all of which have the same diameter and are symmetrically spaced at equal intervals. The lower end of the movement rod 18 is fitted with each of the three positioning grooves 10. By successively inserting the movement rod 18 into the three positioning grooves 10, the distance of the inner tube 5 within the sleeve 7 can be adjusted. A limiting ring 21 is fixedly attached to the surface of the movement rod 18.The edge of the limiting ring 21 is in contact with the inner wall of the housing 13 and is slidably connected to it. The sliding of the limiting ring 21 on the inner wall of the housing 13 achieves the limiting effect for the moving rod 18. A spring 20 is attached to the surface of the moving rod 18. One end of the spring 20 is fixed to the top of the limiting ring 21, and the other end of the spring 20 is fixed to the inner wall of the housing 13. The lower end of the moving rod 18 movably pierces the outer surface of the sleeve 7 and rests against the outer surface of the inner tube 5.Under the vertical elastic potential energy of the spring 20, the lower end of the moving rod 18 presses against the positioning groove 10 formed on the outer surface of the inner tube 5, thereby limiting the inner tube 5 and ensuring the fixing effect after the overlap of the positions of the through holes 16 and the liquid outlet openings 11.

[0019] As in Fig. 1, Fig. 2 and Fig.As shown in Figure 4, a removable component is arranged on the metal stent 1. The removable component comprises a threaded rod 14, which is fixedly connected to the underside of the support block 6. Threaded holes 2 are provided on the top of the metal stent 1, and the surface of the threaded rod 14 is screwed to the inside of the threaded holes 2. The use of a detachable connection facilitates the assembly and disassembly of the upper sleeve 7 and the screw 8. A nut 15 is screwed onto the surface of the threaded rod 14, with the side of the nut 15 adjacent to the metal stent 1 in contact with it. The arrangement of the nut 15 improves the stability of the threaded rod 14 after assembly. There are several threaded holes 2, arranged symmetrically in a ring at equal intervals.By tightening the screw rod 14 in threaded holes 2 at different positions, the sleeve 7 and the screw 8 can be adjusted to different positions, thereby improving flexibility in the repair of the necrotic bone area.

[0020] Working principle: First, a suitable anesthetic procedure is selected according to the location of the bone necrosis and the patient's circumstances. A suitable surgical incision is made at the site of bone necrosis. The incision must be large enough to completely expose the necrotic bone tissue while minimizing damage to the surrounding tissues. The necrotic bone is carefully removed through the incision, after which the metal stent 1 is placed at the prepared bone defect site. During implantation of the metal stent 1, its center point must align with the center point of the femoral head, and the rim of the metal stent 1 must conform closely to the edge of the femoral head to ensure even support.By moving the inner tube 5 on the inside of the sleeve 7, the position of the inner tube 5 is adjusted until the through-holes 16 formed on the outer wall of the inner tube 5 align with the fluid outlet openings 11. Osteoblasts are then injected into the interior of the inner tube 5. Next, the screw 8 is screwed into the bone tissue to firmly connect the bone to the metal stent 1. The button 19 is pulled, causing it to move the actuating rod 18 upwards. The limiting ring 21 moves upwards with the actuating rod 18, compressing the spring 20 until the lower end of the actuating rod 18 is separated from the positioning groove 10. The inner tube 5 is then positioned within the sleeve 7, with the overlap position between the through-holes 16 and the fluid outlet openings 11 being precisely adjusted to achieve the required implantation position for bone cells.After the desired implantation position has been determined, the button 19 is released. Under the influence of the vertical elastic potential energy of the spring 20, the actuating rod 18 rebounds, and its lower end comes into contact with the positioning groove 10 formed on the outer wall of the inner tube 5. This ensures reliable positional limitation for the inner tube 5 and guarantees the fixation effect after the overlap of the through-holes 16 with the fluid outlet openings 11. Subsequently, the push plate is manipulated laterally, so that the button 19 moves the piston rod 9 and the sealing plug 17 along the inner wall of the inner tube 5. Based on the syringe principle, the cell suspension is injected into the interior of the metal stent 1 – this procedure ensures highly precise delivery of the cells to the predetermined implantation site. Reference symbol list 1 metal stent 2 threaded holes 3 Extension block 4 telescopic poles 5 inner tube 6 Support block 7 Sleeve 8 screws 9 Piston rod 10 Positioning groove 11 Liquid outlet 12 Damping pivot axis 13 cases 14 screw rod 15 mother 16 through hole 17 sealing plugs 18 Movement bar 19 key 20 springs 21 Boundary ring

Claims

[1] Bone necrosis repair stent with osteoblast implantation function, comprising a metal stent (1), wherein extension blocks (3) are rigidly connected to the outside of the metal stent (1), and the metal stents (1) are pivotally connected to telescopic rods (4) via the extension blocks (3), support blocks (6) are arranged on the metal stent (1), wherein damping pivot axes (12) are rigidly connected to the top of the support blocks (6), and the top of the support blocks (6) are rotatably connected to sleeves (7) via the damping pivot axes (12), wherein fluid outlet openings (11) are formed on the surface of the sleeves (7), and the inside of the sleeves (7) is in contact with inner tubes (5), wherein through holes (16) are provided on the outside of the inner tubes (5), and piston rods (9) are movably inserted through one end of the inner tubes (5), wherein at one end of the Piston rods (9) are firmly connected to a sealing plug (17),wherein the edge of the sealing plug (17) is in contact with the inner wall of the inner tubes (5), push plates are firmly connected at the other end of the piston rods (9) and limiting components are arranged on the outside of the sleeves (7). [2] Bone necrosis repair stent according to claim 1, characterized by , that the limiting component comprises a housing (13) which is attached to the outside of the sleeve (7), wherein a movement rod (18) is movably inserted through the top of the housing (13), a button (19) is attached to the tip of the movement rod (18), and positioning grooves (10) are provided on the outer wall of the inner tube (5). [3] Bone necrosis repair stent according to claim 1 or 2, characterized by, that a removable component is arranged on the metal stent (1), wherein the removable component comprises a screw rod (14) which is attached to the underside of the support block (6), and that a threaded hole (2) is provided on the top of the metal stent (1), wherein the surface of the screw rod (14) is screwed to the inside of the threaded hole (2). [4] Bone necrosis repair stent according to claim 2, characterized by , that the number of positioning grooves (10) is three, wherein the three positioning grooves (10) have the same hole diameter and are arranged symmetrically at equal intervals, and wherein the lower ends of the movement rods (18) each interact appropriately with the three positioning grooves (10). [5] Bone necrosis repair stent according to claim 3, characterized by, that a nut (15) is screwed onto the surface of the screw rod (14), the nut (15) being located on the side facing the metal stent (1), and that the number of threaded holes (2) is several, which are arranged symmetrically in a ring shape at equal intervals. [6] Bone necrosis repair stent according to any of the preceding claims, characterized by , that the number of liquid outlet openings (11) is three, wherein the three liquid outlet openings (11) have the same hole diameter and are arranged symmetrically at equal intervals, and that the through holes (16) provided on the outer wall of the sleeve (7) each interact appropriately with the three liquid outlet openings (11). [7] Bone necrosis repair stent according to claim 2, characterized by, that a limiting ring (21) is firmly attached to the surface of the moving rod (18), wherein the edge of the limiting ring (21) is in contact with the inner wall of the housing (13) and is slidably connected. [8] Bone necrosis repair stent according to claim 2, characterized by , that a spring (20) is mounted on the surface of the moving rod (18), wherein one end of the spring (20) is fixedly connected to the top of the limiting ring (21), the other end is fixedly connected to the inner wall of the housing (13), and that the lower end of the moving rod (18) movably penetrates the outer surface of the sleeve (7) and rests against the outer surface of the inner tube (5). [9] Bone necrosis repair stent according to claim 3, characterized by , that a threaded groove is provided at one end of the sleeve (7), wherein the wall of the threaded groove is screwed to the screw (8).

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