COMPOSITIONS AND METHODS FOR IDENTIFYING RARE CELLS

DE602017092487T2Active Publication Date: 2025-10-29X ZELL INC
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Patent Information

Application Number
DE602017092487
Authority / Receiving Office
DE · DE
Patent Type
Patents
Current Assignee / Owner
Priority Date
2016-12-06
Filing Date
2017-03-06
Publication Date
2025-10-29
Estimated Expiration
2037-03-06

AI Technical Summary

Technical Problem

Existing methods for identifying circulating tumor cells (CTCs) are limited by high false positives, damage to cells during preparation, loss of RNA, and difficulty in staining multiple biomarkers, leading to inaccurate detection and analysis.

Method used

A computer-implemented method using image processing and machine learning to identify CTCs by measuring pixel intensity and fluorescence, combined with specific staining and fixing techniques to preserve cell integrity and enhance contrast, along with a reagent system for fixing and blocking non-specific binding sites.

Benefits of technology

Enhances the ability to accurately detect and characterize CTCs at a molecular level, improving cancer screening and reducing the need for invasive procedures.

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