Cosmetic composition and its uses

Abstract

In some aspects, the techniques of the invention relate to a cosmetic composition having improved oxygen supply properties, the composition comprising: a spirulina extract; a carrier; an optional texturizing agent; and an antioxidant.

Description

Title of the invention: COSMETIC COMPOSITION AND ITS USES CONTEXT

[0001] Oxygen can be supplied to the skin by various methods. It is therefore desirable to increase the supply of oxygen to the skin. Summary of the invention

[0002] In certain aspects, the techniques of the invention relate to a cosmetic composition having improved oxygen delivery properties, the composition comprising: a spirulina extract; a carrier; an optional texturizing agent; and an antioxidant. DETAILED DESCRIPTION OF THE INVENTION

[0003] Reference will now be made in detail to certain aspects of the disclosed subject matter. While the disclosed subject matter will be described in conjunction with the enumerated claims, it will be understood that the disclosed subject matter illustrated by example is not intended to limit the claims to the disclosed subject matter.

[0004] Throughout this document, values ​​expressed in a range format are to be flexibly interpreted to include not only the numerical values ​​explicitly stated as limits of the range, but also to include all individual numerical values ​​or subranges within that range as if each numerical value and subrange were explicitly stated. For example, a range of "about 0.1% to about 5%" or "about 0.1% to 5%" is to be interpreted to include not only about 0.1% to about 5%, but also individual values ​​(e.g., 1%, 2%, 3%, and 4%) and subranges (e.g., 0.1% to 0.5%; 1.1% to 2.2%; 3.3% to 4.4%) within the stated range. The statement "about X to Y" has the same meaning as "about X to about Y" unless otherwise stated.Similarly, the statement "about X, Y, or about Z" has the same meaning as "about X, about Y, or about Z" unless otherwise stated.

[0005] In this document, the terms "a," "an," or "the" are used to include one or more than one, unless the context clearly indicates otherwise. The term "or" is used to refer to a non-exclusive "or" unless otherwise indicated. The statement "at least one of A and B" or "at least one of A or B" has the same meaning as "A, B, or A and B." In addition, it is to be understood that phraseology or terminology used herein, and not otherwise defined, is for the purpose of description only and not of limitation. Any use of section headings is intended to assist in the reading of the document and should not be construed as limiting; information that is relevant to a section heading may appear within or outside that particular section. A non-breaking space may be used to delimit or separate groups of digits to the left or right of a decimal point; for example, “0.000 1” is equivalent to “0.0001”.

[0006] In the methods described herein, the acts may be performed in any order without departing from the principles of the invention, except where a temporal or operational sequence is explicitly stated. Furthermore, specified acts may be performed simultaneously unless the explicit claim language states that they are performed separately. For example, a claimed action of doing X and a claimed action of doing Y may be conducted simultaneously in a single operation, and the resulting process will fall within the literal scope of the claimed process.

[0007] The term "about" as used herein may allow for a degree of variability of a value or range, for example, within 10%, within 5%, or within 1% of a stated value or stated limit of a range and includes the exact stated value or range. The term "substantially" as used herein refers to a majority, or substantially, as in at least about 50%; 60%; 70%; 80%; 90%; 95%; 96%; 97%; 98%; 99%; 99.5%; 99.9%; 99.99%; or at least about 99.999% or more; or 100%.The term "substantially free of" as used herein may mean having no or an insignificant amount of, such that the amount of material present does not affect the material properties of the composition comprising the material, such that about 0 wt% to about 5 wt% of the composition is the material, or about 0 wt% to about 1 wt%, or about 5 wt% or less, or an amount less than or equal to about 4.5 wt%; 4; 3.5; 3; 2.5; 2; 1.5; 1; 0.9; 0.8; 0.7; 0.6; 0.5; 0.4; 0.3; 0.2; 0.1; 0.01; or about 0.001 wt% or less, or about 0 wt%.

[0008] According to various aspects of the present disclosure, a cosmetic composition is capable of supplying oxygen to skin tissue. Supplying oxygen to skin tissue can be useful in many different applications. For example, the composition can be used as an anti-aging composition, a firming composition, an anti-wrinkle composition, an anti-pigment spot composition, a skin barrier and repair treatment, a skin hydrating composition, an anti-pollution and detoxifying composition, a topical skin protective and lightening preparation containing mineral and organic UV filters, active agents for tanning preparation actions or soothing agents for after-sun treatments or potentially a combination thereof. The cosmetic composition is a topical formulation: an O / W emulsion, an emulsion W / O, micro-emulsions or multiple emulsions such as a cream, a lotion, a gel, a serum, a spray, a mask, a cleanser, a micellar water, a self-tanning product, an oil (single phase or multi-phase), a sunscreen product, all being classic facial, body care and color treatments.

[0009] The cosmetic composition comprises spirulina platensis, which is a cyanobacterium biomass. Spirulina platensis may be present in the form of an aqueous extract. In addition to spirulina, the extract may comprise glycerin. The spirulina platensis extract comprises an active ingredient which ultimately provides oxygen. This active ingredient would be phycocyanin, which is a protein belonging to the phycobili-protein family present in particular in algae. Phycocyanin can be isolated and purified from species, such as Aphanizomenonflo saqua, Arthrospiraplatentis, Spirulinafusiformis, Phormidium sp., Lyngbya sp., Synechosystis sp. and Synechococcus sp., is a protein complex of the light-harvesting family, along with phycoerythrin. It is an auxiliary pigment of chlorophyll. Each subunit is typically composed of eight α-helices. Monomers aggregate spontaneously to form ring-shaped (α[3)3) trimers, which have rotational symmetry and a central channel. Trimers aggregate in pairs to form (α[3)6) hexamers, sometimes with the help of additional linker proteins. Each phycobilisome rod typically has two or more phycocyanin hexamers. Despite the overall similarity in structure and assembly of phycobiliproteins, there is a great diversity of hexameric and rod conformations, even when considering only phycocyanins.

[0010] Based on the total concentration of the cosmetic composition, the spirulina platensis extract may be in a range of about 0.00001 wt% to about 10 wt%; about 0.00005 wt% to about 8 wt%; about 0.00008 wt% to about 0.012 wt%; an amount less than, equal to, or greater than about 0.00001 wt%; 0.00005; 0.00010; 0.000050; 0.001; 0.005; 0.01; 0.02; 0.03; 0.04; 0.05; 0.06; 0.07; 0.08; 0.09; 0.1; 0.11; 0.12; 0.13; 0.14; 0.15; 0.16; 0.17; 0.18; 0.19; 0.2; 0.3; 0.4; 0.5; 1; 1.5; 2; 2.5; 3; 3.5; 4; 4.5; 5; 5.5; 6; 6.5; 7; 7.5; 8; 8.5; 9; 9.5; or about 10% by weight.

[0011] The carrier of the cosmetic composition may be a clay or a liposome. Examples of suitable clays may include bentonite, hectorite, stearalkonium hectorite and propylene carbonate, rhassoul clay, French green clay, Fuller's earth clay, yellow clay or a mixture thereof. Stearalkonium hectorite in combination with propylene carbonate is preferred.

[0012] Liposomes are considered to be the most commonly used nanocarriers for various potentially active hydrophobic and hydrophilic molecules due to their high biocompatibility, biodegradability, and low immunogenicity. Liposomes have also demonstrated the ability to enhance the solubility and regulated distribution of drugs, as well as their surface modification capability for targeted delivery in the skin, prolonged and sustained release. Based on this composition, liposomes can be considered to have evolved from conventional, long-circulating, targeted, and immune liposomes to stimuli-responsive and actively targeted liposomes. Many liposome-based drug delivery systems are currently clinically approved to treat several diseases, such as cancer, fungal, and viral infections; more liposomes have reached advanced stages in clinical trials.According to their structures, liposomes are classified into four categories based on the size and number of bilayers: small unilamellar vesicles (SUVs), large unilamellar vesicles (LUVs), multilamellar vesicles (MLVs), and multivesicular vesicles (MWs). Liposomes have a monophospholipid bilayer in a unilamellar structure, while they have an onion-like structure in a multilamellar structure. MWs form a multilamellar arrangement with concentric phospholipid spheres since many unilamellar vesicles are produced within larger liposomes. Vesicle size is an important factor that regulates the circulating half-life of liposomes. Both the size and the number of bilayers influence the amount of the encapsulated drug.The interaction of liposomes with the cell membrane is represented by various theories: specific (receptor-mediated) or nonspecific endocytosis, local fusion (adhesion), phagocytosis, and uptake into the cell membrane. Liposome-cell interactions are influenced by a variety of factors, including composition, liposome diameters, surface charge, targeting ligand on the liposome surface, and the biological environment.

[0013] Based on the total concentration of the cosmetic composition, the carrier is in a range of about 0.01 wt% to about 70 wt%; about 20 wt% to about 50 wt%; an amount less than, equal to, or greater than about 0.01 wt%; 0.5; 1; 1.5; 2; 3; 4; 5; 6; 7; 8; 9; 10; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30; 31; 32; 33; 34; 35; 36; 37; 38; 39; 40; 41; 42; 43; 44; 45; 46; 47; 48; 49; 50; 51; 52; 53; 54; 55; 56; 57; 58; 59; 60; 61; 62; 63; 64; 65; 66; 67; 68; 69; or about 70% in weight.

[0014] The texturizing agent emollient (for example) may comprise a mixture of dicaprylyl carbonate and tocopherol, a mixture of caprylic / capric triglyceride, a mixture of caprylic / capric triglyceride and castor oil / ipdi copolymer, or a combination thereof. Additional examples of emollients include mono-, di-, and tri-glycerides and butters and hydrogenated versions of seed and nut oils including, but not limited to; palm oil, coconut oil, vegetable oil, avocado oil, rapeseed oil, corn oil, soybean oil, sunflower oil, safflower oil, Limnanthes douglasii seed oil, blueberry seed oil, watermelon seed oil, olive oil, cranberry oil, macadamia nut oil, argan oil, pomegranate oil, Moroccan argan oil, blueberry oil, raspberry oil, walnut oil, pecan oil, peanut oil, bay oil, mango seed oil, wing pea oil, castor oil; shea butter, jojoba oil, hydrolyzed jojoba oil, carnauba butter, carnauba wax, stearyl heptanoate succinate castor isostearate, cetyl ricinoleate, oleyl fructate, sucrose monostearate, sucrose distearate, sucrose tristearate,sucrose tetrastearate, candelabra cera, soybean wax, rapeseed wax, palm wax, beeswax, petrolatum, myristyl myristate, oleyl erucate, squalane, stearyl alcohol, cetearyl isononanoate, polyisobutene, glyceryl stearate, glyceryl distearate, cetyl alcohol, lanolin, lanolin ethoxylate, low molecular weight polyethylene waxes, low molecular weight polypropylene waxes, PEG-30 glyceryl cocoate, PEG-80 glyceryl cocoate, glyceryl stearate, PEG-8 ricinoleate, PEG-8 raspberry, linear (also known as bis) and pendant versions of including hydroxyl-terminated and methyl ether-terminated; PEG-3 to PEG-32 dimethicone (including, but not limited to: PEG-3 dimethicone, PEG-9 dimethicone, PEG-10 dimethicone, PEG-11 dimethicone, methyl ether dimethicone, PEG-12 dimethicone, PEG-14 dimethicone, PEG-17 dimethicone, PEG dimethicone),bis-PEG / PPG-20 / 20 dimethicone, PEG / PPG 20 / 23 dimethicone, PEG / PPG 20 / 22 dimethicone, butyl ether dimethicone, PEG / PPG 23 / 6 dimethicone, PEG / PPG 20 / 15 dimethicone. Alkyl Modified Dimethicone (Stearoxy Dimethicone, Behenoxy Dimethicone, Cetyl Dimethicone, Cetearyl Methicone C30-45 Alkyl Cetearyl Dimethicone Copolymer, Alkyl Dimethicone, Caprylyl Methicone, PEG-8 Dimethicone / Dimer Dilinoleic Acid Copolymer, Bis-PEG-10 Dimethicone / Dimer Dilinoleate Copolymer, Stearoxymethicone / Dimethicone Copolymer, Diphenyl Dimethicone, Lauryl Polyglycerol-3 Polydimethylsiloxyethyl Dimethicone, PEG-9 Lauryl Polydi-methylsiloxyethyl Dimethicone), Dimethicone Fluid (>20 est), Quaternized Ammonia Silicone Polymers, Amino Silicones, Quaternized Silicone-18, Amodi-Methicone, phenyl trimethicone, amino silicone polyethers, polyglycerol-3 disiloxane dimethicone, polyglycerol-3 polydimethylsiloxyethyl dimethicone, silica dimethyl silylate,bambusa arundinacea, and PEG-9 polydimethylsiloxyethyl dimethicone. ,

[0015] Relative to the total concentration of the cosmetic composition, the texturizing agent is in a range of about 10% by weight to about 60% by weight; from about 20% by weight to about 40% by weight; in an amount less than, equal to, or greater than about 10% by weight; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30; 31; 32; 33; 34; 35; 36; 37; 38; 39; 40; 41; 42; 43; 44; 45; 46; 47; 48; 49; 50; 51; 52; 53; 54; 55; 56; 57; 58; 59; or about 60% by weight.

[0016] Antioxidants slow down, protect against, and promote repair of the undesirable effects of oxidative degradation. The antioxidant may comprise a mixture of diethylhexyl syringylidenemalonate and caprylic / capric triglyceride, or a combination thereof. Other antioxidants include vitamin C and its derivatives, niacinamide, resveratrol, vitamin E and its derivatives, retinol and its derivatives, coenzyme Q10, as well as polyphenols and diethylhexyl syringylidenemalonate. Based on the total concentration of the cosmetic composition, the antioxidant is in a range of about 0.05% by weight to about 20%; from about 5% by weight to about 15% by weight; in an amount less than, equal to, or greater than 2% by weight; 3; 4; 5; 6; 7; 8; 9; 10; 11; 12; 13; 14; 15; 16; 17; 18; 19; or about 20% by weight.

[0017] A specific example of a cosmetic composition in which spirulina platensis is present in a liposomal carrier comprises the composition shown in Table 1.

[0018] [Table 1] Component (INCI) % by weight LECITHIN AND ALCOHOL 3 to 8 GLYCERIN 10 to 20 PROPYLENE GLYCOL 3 to 8 GLYCERIN AND WATER AND SPIRULINA PLATENSIS EXTRACT 3 to 8 DIETHYLHEXYL SYRINGYLIDENEMALONATE AND CA-PRYLIC / CAPRIC TRIGLYCERIDE 0.05 to 0.15 WATER 60 to 70 BENZYL ALCOHOL AND BENZOIC ACID AND DEHYDROACETIC ACID 0.5 to 1.5 WATER AND SODIUM HYDROXIDE 0.05 to 0.30

[0019] A specific example of a cosmetic composition in which spirulina platensis is present in a clay support having the composition presented in Table 2.

[0020] [Table 2]: Component (INCI) % by weight DICAPRYLYL CARBONATE AND TOCOPHEROL 35 to 45 CAPRYLIC / CAPRIC TRIGLYCERIDE 10 to 15 CAPRYLIC / CAPRIC TRIGLYCERIDE AND CASTOR OIL / IPDI COPOLYMER 0.25 to 0.75 SILICA DIMETHYL SILYLATE 0.5 to 2 TOCOPHERYL ACETATE 0.25 to 0.75 WATER AND GLYCERIN AND SPIRULINA PLATENSIS EXTRACT 3 to 7 DIE-ETHYLHEXYL SYRINGYLIDENEMALONATE AND CAPRYLIC / CAPRIC TRIGLYCERIDE 0.05 to 0.15 CAPRYLIC / CAPRIC TRIGLYCERIDE AND STEARALKONIUM HECTORITE AND CARBONATE PROPYLENE 35 to 45

[0021] In addition to the aforementioned components, the cosmetic composition may comprise any compound generally accepted in the cosmetic and dermatological fields. The invention makes it possible to obtain a multitude of compositions.

[0022] The cosmetic composition may comprise anti-aging and / or anti-wrinkle compounds, alone or in a mixture, chosen from the group comprising adenosine, hyaluronic acid, coca leaf extract and tocopheryl acetate. It is particularly advantageous to combine phycocyanin and a compound having anti-wrinkle, anti-aging or antioxidant activity so as to obtain compositions having increased anti-aging activity.

[0023] The cosmetic composition may comprise a moisturizing and soothing compound such as mineral water and glycerin. The cosmetic composition may comprise gelling and texturizing compounds, alone or in a mixture, chosen from the group consisting of a crosslinked polyacrylate polymer; a crosslinked polymethyl polymer; polymethyl methacrylate; talc; boron nitride; isocetyl stearate; xanthan gum; hydroxypropylmethylcellulose; hydroxyethylcellulose; a hydroxyethyl acrylate / sodium acryloyldemethyltaurate copolymer and water and squalane and polysorbate 60 and sorbitan isostearate; acrylates / C10-30 alkyl acrylate crosspolymer; water and acrylates / vinyl neodecanoate crosspolymer; hydroxyethyl acrylate / sodium acrylmimethyl taurate copolymer and polysorbate 60 and sorbitan isostearate and water; magnesium aluminum silicate; carrageenan; alginate; calcium alginate; sodium polyacrylate starch; (hydroxypropyl) starch; starch powders (from rice, corn, cassava or tapioca); hydroxypropyl starch phosphate and water; pectin; gelatin; agar; gellan gum; sclerotium gum; tragacanth; tapioca starch; guar gum; locust bean gum; acacia gum; gum arabic.

[0024] The cosmetic composition may comprise preservatives, alone or in a mixture, chosen from the group consisting of chlorphenesin, o-cymen-5-ol and 1,2-hexanediol; benzyl alcohol; benzoic acid; dehydroacetic acid; Musa Sapientum (banana) extract; sodium benzoate and potassium sorbate; ethylhexylglycerin; or a mixture thereof.

[0025] The cosmetic composition may comprise emulsifying agents, alone or in a mixture, chosen from the group consisting of potassium cetyl phosphate, C20-22 alkyl phosphate and C20-22 alcohols, glyceryl stearate, PEG-100 stearate, polysorbate 60, cetyl alcohol, stearyl alcohol, stearic acid and palmitic acid, polyglyceryl-6 stearate and polyglyceryl-6, PEG-20 tribehine esters, cetearyl alcohol and cetearyl glucoside, hydrogenated coconut glycerides, PEG-40 hydrogenated castor oil, glyceryl stearate (SE), PEG-100 stearate and glyceryl, or a mixture thereof.

[0026] The cosmetic composition may comprise thickening agents, alone or in a mixture, chosen from the group consisting of cetyl alcohol, vegetable waxes such as jojoba ester and black acacia flower wax, black acacia flower and annual sunflower seed wax, beeswax (cera alba), carnauba wax, and mixtures thereof.

[0027] The cosmetic composition may comprise film-forming agents, alone or in a mixture, selected from the group consisting of isononyl isononanoate, di-methicone and plant gels such as tara extract, kappaphycus alvarezii extract, kappaphycus alvarrezii extract, konjac mannan, chitosan, and gum with added biosaccharide, capryloyl glycerin / sebacic acid copolymer, other bio-based polymers made from tung or rapeseed or other plant oils, ethylcellulose and diisopropyl adipate, or a mixture thereof.

[0028] The cosmetic composition may comprise solvents, alone or in a mixture, chosen from the group consisting of water, dicaprylyl carbonate, propylene glycol, dipropylene glycol, ethanol, butylene glycol, or a mixture thereof.

[0029] The cosmetic composition may comprise pH adjusting agents, alone or in a mixture, chosen from the group consisting of citric acid, sodium hydroxide and trometamol.

[0030] The cosmetic composition may comprise lipid regeneration agents, alone or in a mixture, chosen from the group consisting of squalane and shea butter, as well as butters derived from mango seed, olive, almond, cocoa, coconut, macadamia nut, or babassu.

[0031] The cosmetic composition may comprise stabilizing agents, alone or in a mixture, as well as emulsifiers chosen from the functional ingredients mentioned above.

[0032] The cosmetic composition may comprise hydrogenated vegetable oil, co-camidopropyl betaine and glyceryl oleate, mica, tin oxide and titanium dioxide or other pigments and pearl powders.

[0033] The cosmetic composition may comprise anti-UV agents, alone or in a mixture, chosen from the group consisting of butylmethoxydibenzoylmethane, octocrylene, ethylhexyl methoxycinnamate, octyl salicylate, ethylhexyltriazone and bis-ethylhexyloxyphenolmethoxyphenyltriazine.

[0034] The cosmetic composition may also comprise caffeine, niacinamide, vitamins of groups E, A, C and F and their derivatives, creatine palmitoyl tripeptide-5, panthenol, or mixtures thereof. EXAMPLES

[0035] The compositions among those listed in Table 1 and Table 2 were investigated in terms of oxygen loading capabilities. To carry out the oxygen loading, a VisionAire 5 oxygen concentrator from CAIRE Inc., US is used. With the oxygen concentrator, air is drawn into the device through its air inlets, where the air passes through a molecular sieve. The oxygen is separated from the nitrogen and only pure oxygen can exit the device. This results in a high concentration stream of pure (medical) quality. A specific connected tubing transports the pure oxygen to its destination in the carriers which are prepared as described below.

[0036] The air flow rate was 1 to 5 L / min. The chosen phycocyanin support system (composition from Table 1 or Table 2) is loaded into a beaker (covered with plastic film) with slow to medium speed stirring using a conventional Raynerie Turbotest (VMI, France) or IKA RW 20 Digital mixer. Mixer (IKA Werke, Germany). The newly produced O2 flows from the O2 concentrator through a special silicone tubing (Westmed, Inc., US) into the holder. The loading time and flow rate depend on the volumes to be loaded from 100 mL to 5 L. The protocol is optimized by choosing a loading time of 1 to 30 minutes with a flow rate of 1 to 5 L / min.

[0037] The results are shown below in Figures 1 and 2. [Fig.l] shows the partial O2 concentration in a liposomal carrier composition. The liposomal carrier composition is as shown in Table 1. The partial O2 concentration values ​​are plotted on the ordinate and time is plotted on the abscissa. [Fig.2] shows the partial O2 concentration in a stearalkonium hectorite carrier composition. The stearalkonium hectorite carrier composition is as shown in Table 2. The partial O2 concentration values ​​are plotted on the ordinate and time is plotted on the abscissa.

[0038] The amount of oxygen increase in cells treated with the compositions according to Table 1 and Table 2, respectively, was studied. The results are shown in [Fig. 3]. To generate the data, hypoxia states were induced in normal human fibroblasts using dimethyloxa-lylglycine treatment. Once hypoxia was generated, the cells were then incubated with the respective compositions. The intracellular oxygen content was quantified using the Winkler method. The Winkler method typically involves completely filling a sample vial with water (the absence of air ensures that the assay is not biased). The dissolved oxygen is then “fixed” using a series of reagents that form an acidic compound that is titrated. The titration involves the dropwise addition of a reagent that neutralizes the acidic compound and causes a color change in the solution.The point of color change is called the "end point" and is equivalent to the amount of dissolved oxygen in the sample. The sample is usually fixed and titrated on site at the sampling site. However, it is possible to prepare the sample on site and transport it to a laboratory for titration. The oxygen content was compared to untreated cells. Examples of aspects

[0039] The following examples of aspects are provided, their numbering should not be interpreted as indicative of levels of importance.

[0040] Aspect 1 provides a cosmetic composition having improved oxygen delivery properties, the composition comprising:

[0041] a spirulina extract;

[0042] a support;

[0043] a texturizing agent; and

[0044] an antioxidant.

[0045] Aspect 2 provides the cosmetic composition of aspect 1, wherein the spirulina platensis extract is an aqueous extract.

[0046] Aspect 3 provides the cosmetic composition of aspect 2, wherein the spirulina platensis extract is an aqueous extract and further comprises glycerin.

[0047] Aspect 4 provides the cosmetic composition of any one of aspects 1 to 3, wherein the active spirulina platensis extract is in a range of about 1% by weight to about 10% by weight.

[0048] Aspect 5 provides the cosmetic composition of any one of aspects 1 to 4, wherein the spirulina platensis extract is in a range of about 3 wt% to about 8 wt%.

[0049] Aspect 6 provides the cosmetic composition of any one of aspects 1 to 5, wherein the spirulina platensis extract comprises an active ingredient.

[0050] Aspect 7 provides the cosmetic composition of aspect 6, wherein the active ingredient comprises phycocyanin.

[0051] Aspect 8 provides the cosmetic composition of any one of aspects 1 to 7, wherein the carrier comprises a clay or a liposome and the liposome optionally comprises a cationic charge and an EGF ligand.

[0052] Aspect 9 provides the cosmetic composition of aspect 8; wherein the clay comprises bentonite hectorite

[0053] Aspect 10 provides the cosmetic composition of any one of aspects 1 to 9, wherein the carrier is in a range of about 1 wt% to about 60 wt%.

[0054] Aspect 11 provides the cosmetic composition of any one of aspects 1 to 10, wherein the carrier is in a range of about 20 wt% to about 50 wt%.

[0055] Aspect 12 provides the cosmetic composition of any one of aspects 1 to 11, wherein the texturizing agent comprises a mixture of, or a combination thereof.

[0056] Aspect 13 provides the cosmetic composition of any one of aspects 1 to 12, wherein the texturizing agent is in a range of about 10 wt% to about 60 wt%.

[0057] Aspect 14 provides the cosmetic composition of any one of aspects 1 to 13, wherein the texturizing agent is in a range of about 20 wt% to about 40 wt%.

[0058] Aspect 15 provides the cosmetic composition of any one of aspects 1 to 14, wherein the antioxidant comprises a mixture of diethylhexyl syringylidenemalonate and caprylic / capric triglyceride, or a combination thereof.

[0059] Aspect 16 provides the cosmetic composition of any one of aspects 1 to 15, wherein the antioxidant is in a range of about 2% by weight to about 20% by weight of the composition.

[0060] Aspect 17 provides the cosmetic composition of any one of aspects 1 to 16, wherein the antioxidant is in a range of about 5 wt% to about 15 wt% of the composition.

[0061] Aspect 18 provides a cosmetic composition comprising:

[0062] [Table 3] Component (INCI) % by weight LECITHIN AND ALCOHOL 3 to 8 GLYCERIN 10 to 20 PROPYLENE GLYCOL 3 to 8 GLYCERIN AND Water AND SPIRULINA PLATENSIS EXTRACT 3 to 8 DIE-THYLHEXYL SYRINGYLIDENEMALONATE AND CAPRYLIC / CAPRIC TRIGLYCERIDE 0.05 to 0.15 WATER 60 to 70 BENZYL ALCOHOL AND BENZOIC ACID AND DEHYDRACETIC ACID 0.5 to 1.5 WATER AND SODIUM HYDROXIDE 0.05 to 0.30

[0063] Aspect 19 provides a cosmetic composition comprising:

[0064] [Table 4] Component (INCI) % by weight DICAPRYLYL CARBINATE AND TOCOPHEROL 35 to 45 CAPRYLIC / CAPRIC TRIGLYCERIDE 10 to 15 CAPRYLIC / CAPRIC TRIGLYCERIDE AND CASTOR OIL / IPDI COPOLYMER 0.25 to 0.75 SILICA DIMETHYL SILYLATE 0.5 to 2 TOCOPHERYL ACETATE 0.25 to 0.75 WATER AND GLYCERIN AND SPIRULINA PLATENSIS EXTRACT 3 to 7 DIE-SYRINGYLIDENEMALONATE 0.05 to 0.15 THYLHEXYL AND CA-PRYLIC / CAPRIC TRIGLYCERIDE CAPRYLIC / CAPRIC TRIGLYCERIDE AND STEARALKONIUM HECTORITE AND PROPYLENE CARBONATE 35 to 45

[0065] Aspect 20 provides the cosmetic composition of any one of aspects 1 to 19, wherein the composition is an anti-aging composition, a firming composition, an anti-wrinkle composition, an anti-pigment spot composition, a skin barrier and repair treatment, a skin hydrating composition, an anti-pollution and detoxifying composition, a topical skin protectant and lightening preparation containing mineral and organic UV filters, active agents for tanning preparation actions or soothing agents for after-sun treatments or potentially a combination thereof.The cosmetic composition is a topical formulation: an O / W emulsion, an W / O emulsion, micro-emulsions or multiple emulsions such as a cream, a lotion, a gel, a serum, a spray, a mask, a cleanser, a micellar water, a self-tanning product, an oil (single phase or multi-phase), a sunscreen product, all being classic facial, body care and color treatments.

[0066] Aspect 21 provides a method of manufacturing the cosmetic composition of any one of aspects 1 to 20, the method comprising mixing the spirulina extract; the carrier; the optional texturizing agent; and the antioxidant.

[0067] Aspect 22 provides a cosmetic carrier comprising:

[0068] a support comprising a clay or a liposome; and optionally;

[0069] an oxygen supply for bubbling into the support.

[0070] Aspect 23 provides a method of using the composition of any one of aspects 1 to 22, the method comprising applying the composition to skin tissue.

Claims

Claims

1. A cosmetic composition having improved oxygen delivery properties, the composition comprising: a spirulina extract; a carrier; an optional texturizing agent; and an antioxidant.

2. A cosmetic composition according to claim 1, wherein the spirulina platensis extract is an aqueous extract.

3. A cosmetic composition according to claim 2, wherein the spirulina platensis extract is an aqueous extract and further comprises glycerin.

4. A cosmetic composition according to any one of claims 1 to 3, wherein the aqueous extract of spirulina platensis is in a range of about 1% by weight to about 10% by weight.

5. A cosmetic composition according to any one of claims 1 to 4, wherein the spirulina platensis extract is in a range of about 3% by weight to about 8% by weight.

6. Cosmetic composition according to any one of claims 1 to 5, in which the spirulina platensis extract comprises an active ingredient.

7. A cosmetic composition according to claim 6, wherein the active ingredient comprises phytocyanin.

8. A cosmetic composition according to any one of claims 1 to 7, wherein the carrier comprises a clay or a liposome and the liposome optionally comprises a cationic charge and an EGF ligand.

9. A cosmetic composition according to claim 8, wherein the clay comprises stearalkonium hectorite.

10. A cosmetic composition according to any one of claims 1 to 9, wherein the carrier is in a range of about 1% by weight to about 70% by weight.

11. A cosmetic composition according to any one of claims 1 to 10, wherein the carrier is in a range of about 20% by weight to about 50% by weight.

12. A cosmetic composition according to any one of claims 1 to 11, wherein the texturizing agent comprises a mixture of

13.

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16.

17.

18. dicaprylyl carbonate and tocopherol, a mixture of caprylic / capric triglyceride, a mixture of caprylic / capric triglyceride and castor oil / ipdi copolymer, or a combination thereof. The cosmetic composition of any one of claims 1 to 12, wherein the texturizing agent is in a range of about 10% by weight to about 60% by weight. A cosmetic composition according to any one of claims 1 to 13, wherein the texturizing agent is in a range of about 20% by weight to about 40% by weight. A cosmetic composition according to any one of claims 1 to 14, wherein the antioxidant comprises a mixture of diethylhexyl syringylidenemalonate and caprylic / capric triglyceride, tocopheryl acetate, or a combination thereof. A cosmetic composition according to any one of claims 1 to 15, wherein the antioxidant is in a range of about 2% by weight to about 20% by weight of the composition. A cosmetic composition according to any one of claims 1 to 16, wherein the antioxidant is in a range of about 5% by weight to about 15% by weight of the composition. Cosmetic composition comprising: Component (INCI) % by weight LECITHIN AND ALCOHOL 3 to 8 GLYCERIN 10 to 20 PROPYLENE GLYCOL 3 to 8 GLYCERIN AND Water AND SPIRULINA PLATENSIS EXTRACT 3 to 8 DIE-THYLHEXYL SYRINGYLIDENEMALONATE AND CAPRYLIC / CAPRIC TRIGLYCERIDE 0.05 to 0.15 WATER 60 to 70 BENZYL ALCOHOL AND BENZOIC ACID AND DEHYDROACETIC ACID 0.5 to 1.5 WATER AND SODIUM HYDROXIDE 0.05 to 0.30

19. Cosmetic composition comprising: Component (INCI) % by weight DICAPRYLYL CARBINATE AND TOCOPHEROL 35 to 45 CAPRYLIC / CAPRIC TRIGLYCERIDE 10 to 15 CAPRYLIC / CAPRIC TRIGLYCERIDE AND CASTOR OIL / IPDI COPOLYMER 0.25 to 0.75 SILICA DIMETHYL SILYLATE 0.5 to 2 TOCOPHERYL ACETATE 0.25 to 0.75 WATER AND GLYCERIN AND SPIRULINA PLATENSIS EXTRACT 3 to 7 DIE-ETHYLHEXYL SYRINGYLIDENEMALONATE AND CAPRYLIC / CAPRIC TRIGLYCERIDE 0.05 to 0.15 CAPRYLIC / CAPRIC TRIGLYCERIDE AND STEARALKONIUM HECTORITE AND PROPYLENE CARBONATE 35 to 45

20. A cosmetic composition according to any one of claims 1 to 19, wherein the composition is an anti-aging composition, a firming composition, an anti-wrinkle composition, an anti-pigment spot composition, a skin barrier and repair treatment, a skin hydrating composition, an anti-pollution and detoxifying composition, a topical skin protective and lightening preparation containing mineral and organic UV filters, active agents for tanning preparation actions or soothing agents for after-sun treatments or potentially a combination thereof.Cosmetic composition which is a topical formulation: an O / W emulsion, a W / O emulsion, micro-emulsions or multiple emulsions such as a cream, a lotion, a gel, a serum, a spray, a mask, a cleanser, a micellar water, a self-tanning product, an oil (single phase or multi-phase), a sunscreen product, all being classic facial, body care and color treatments.

21. A method of manufacturing the cosmetic composition of any one of claims 1 to 20, the method comprising mixing the spirulina extract; the carrier; the texturizing agent; and the antioxidant.

22. A cosmetic carrier comprising: a spirulina extract, a carrier comprising a clay or a liposome; and an oxygen supply for bubbling into the carrier.

23. 3 A method of using the composition of any one of claims 1 to 20 or 22, the method comprising applying the composition to skin tissue.

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