Process

The purification process for halogenated antimicrobial agents like PCMX and PCMC addresses the issues of residual solvents and impurities by separating phases and crystallizing within a metastable zone, achieving high purity and uniform crystals without harmful solvents, enhancing product quality and environmental safety.

GB2701132APending Publication Date: 2026-04-22THOMAS SWAN & CO LTD
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Patent Information

Authority / Receiving Office
GB · GB
Patent Type
Applications
Current Assignee / Owner
THOMAS SWAN & CO LTD
Filing Date
2025-08-26
Publication Date
2026-04-22

AI Technical Summary

Technical Problem

Conventional industrial processes for producing halogenated aromatic or heteroaromatic antimicrobial agents like PCMX and PCMC face challenges in achieving high purity due to residual solvent perchloroethylene (PERC) and impurities such as meta-xylenol (MX), ortho-chloro-meta-xylenol (OCMX), and dichloro-meta-xylenol (DCMX), leading to poor crystalline form and environmental concerns.

Method used

A purification process involving separation of a crude aqueous slurry into an aqueous and non-aqueous phase, followed by dissolution in an organic solvent and controlled crystallization within the metastable zone to produce a substantially pure antimicrobial agent, avoiding the use of harmful solvents and maintaining the agent in molten form for higher yields.

Benefits of technology

The process achieves a purity of less than 20000 ppm impurities, with controlled crystal growth and uniform size distribution, reducing environmental impact and improving product stability and flow properties.

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Abstract

A process for the purification of an antimicrobial agent, comprising the steps of: (i) providing crude aqueous slurry 201 of the antimicrobial agent in combination with at least one impurity arising f
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Citation Information

Patent Citations

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  • A method for preparing 4-chloro-3,5-dimethylphenol

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  • Process for chlorinating xylenols

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