Industrial use of cell nucleus (chromosome) exchange (replacement) egg cells and resource depletion prevention method

Abstract

To solve a problem that, although animals other than mammals basically hatch and grow after being laid as eggs, among these animals, there are those that are used for industrial purposes such as food and materials for processed products, and it is difficult to sustainably and stably secure target animals, such as those whose complete hatching from eggs is difficult even if they are farmed, and those whose numbers in the natural world are decreasing and whose resources are likely to become depleted in the future.SOLUTION: By applying a technique such as genome editing, a cell nucleus of an animal targeted for industrial use is exchanged (replaced) with a cell nucleus of an egg cell of a sperm egg of a related species animal to hatch the animal targeted for industrial use. This method increases the production of animals for industrial use and solves the problems of difficulty in complete culture and possibility of resource depletion in the future.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to cell-related technologies such as genome editing and applied technologies of hatching and breeding technologies.

Background Art

[0002] Genome editing technology

[0003] Technologies for hatching and breeding industries such as aquaculture [[ID=1S]]

Summary of the Invention

Problems to be Solved by the Invention

[0004] Animals other than mammals such as birds, fish and shellfish, insects, and amphibians hatch and grow from eggs in principle. Among these, even in aquaculture technologies that efficiently produce animals with high added value among animals used in industries such as food and raw materials for processed products, complete aquaculture is difficult and stable production is difficult. There were problems such as a decrease in the number of individuals in nature and a possible future resource depletion.

Means for Solving the Problems

[0005] Apply technologies such as genome editing technology to exchange (replace) the cell nucleus (chromosome) of an animal targeted for industrial use with the cell nucleus (chromosome) of the egg cell of a fertilized egg of a related species of animal. Transplant the cell nucleus of an animal targeted for industrial use into the egg cell of a fertilized egg of a related species of animal. (At this time, the cell nucleus of the egg cell of the fertilized egg to be transplanted is removed in advance.) By this exchange (replacement) of the cell nucleus, it is possible to hatch an animal targeted for industrial use, thus solving the difficulties of complete aquaculture and the possible future resource depletion, which are conventional problems. (Since the cell nucleus of an animal targeted for industrial use is the same regardless of which cell it is in, use the one from an easily obtainable cell.)

Claims

1. By applying techniques such as genome editing technology, the nucleus (chromosome) within the egg cell of a fertilized egg is removed, and the nucleus (chromosome) of another organism (related species) different from the organism that laid the egg is transplanted, and then the organism with the transplanted nucleus (chromosome) is hatched. A method of using the repeated hatching and breeding as products in industries such as aquaculture, poultry farming, and leather processing industries. Also, a method of preventing the depletion of natural resources such as fisheries by repeating hatching, breeding, and releasing. By applying techniques such as genome editing technology, the nucleus (chromosome) within the fertilized egg of "organisms with low added value in industrial use" and "organisms with a large number of habitats in nature and no problem in species conservation" is exchanged with the nucleus (chromosome) of "organisms with high added value in industrial use" and "organisms with a small number of habitats in nature and in crisis of species conservation" (related species), and then hatched and bred for industrial use, or released into nature to prevent the depletion of natural resources. (Since the nucleus (chromosome) of an organism with high added value in industrial use and being the target of hatching and breeding is the same regardless of which cell it is removed from, the nucleus (chromosome) of a cell that is easy to obtain (collect) is used.)

2. In the method according to Claim 1, instead of removing the nucleus (chromosome) within the egg cell of a fertilized egg and transplanting the nucleus (chromosome) of another organism (related species), the entire egg cell of the fertilized egg is removed, and a cell having a differentiation function into various cells such as stem cells, iPS cells, and ES cells of another organism (related species) is transplanted, and then the organism with the transplanted cell is hatched. A method of using the repeated hatching and breeding as products in industries such as aquaculture, poultry farming, and leather processing industries. Also, a method of preventing the depletion of natural resources such as fisheries by repeating hatching, breeding, and releasing. Instead of exchanging (replacing) the nucleus (chromosome) of an organism that laid the egg of a fertilized egg with that of another organism (related species), the egg cell of the organism that laid the egg within the fertilized egg is exchanged with a cell having a differentiation function into various cells such as stem cells, iPS cells, and ES cells of another organism (related species), and then hatched and bred for industrial use, or released into nature to prevent the depletion of natural resources.

3. An organism hatched using the method described in Claim 1 and Claim 2.

4. Services and undertakings using the organism described in Claim 3.