Mite repellent composition and mite repellent product

Abstract

To provide a mite repellent composition having an excellent mite repellent effect against house dust mites even after a long time has elapsed and also having excellent safety for humans and animals.SOLUTION: A mite repellent composition contains: (a) 1,8-cineol and / or 1,4-cineol; and (b) a perfume component, wherein the perfume component includes one or more kinds of perfume compounds having a logP value of 2.0 to 5.5. A blending ratio (a / b) of the component (a) to the perfume compound contained in component (b) is set to 5 to 100 on a mass basis. The perfume compound contained in the component (b) is at least one selected from the group consisting of ethyl cinnamate, allyl caproate, 3-methyl-5-phenyl-1-pentanol, citronellol, δ-dodecalactone, β-ionone, benzyl benzoate, linalyl acetate, geranyl acetate, tricyclodecenyl propionate, benzyl salicylate, limonene, and amyl salicylate.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a mite repellent composition and a mite repellent product for repelling house dust mites. [Background technology]

[0002] In recent years, due to changes in the living environment, there has been an increase in cases of large-scale outbreaks of indoor dust mites, such as brown mites, house dust mites, dust mites, and chiggers. Indoor dust mites not only cause discomfort to people, but also cause problems such as allergic asthma and skin rashes. It has also become clear that the carcasses of house dust mites, which cause allergic asthma, can also cause allergies. Therefore, indoor acaricides have been developed to treat bedding such as pillows, futons, and cushions, but indoor acaricides that often come into direct contact with the skin are required to be safer.

[0003] In light of this situation, technology has been sought that does not kill indoor dust mites, but keeps mites away from people and patients, and several proposals have been made so far. For example, Patent Document 1 discloses plant essential oils such as vetiver oil, patchouli oil, and clove oil as active ingredients of indoor mite control agents. Patent Document 2 also discloses citronellal, linalool, citral, etc. Although these conventional technologies claim to be natural and considerate of safety, their repellent effect on indoor dust mites is not necessarily satisfactory.

[0004] Meanwhile, cineole has been attracting attention as a pest repellent ingredient. Patent Document 3 discloses a house dust mite repellent containing 1,8-cineole as an active ingredient. However, since 1,8-cineole and 1,4-cineole are relatively highly volatile, it has been considered difficult to maintain the mite repellent effect for a long period of time of more than 2 to 3 months. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Publication No. 6-16515 [Patent Document 2] JP 2001-294505 A [Patent Document 3] JP 2001-31508 A Summary of the Invention [Problem to be solved by the invention]

[0006] The present invention has been made in consideration of the above-mentioned problems, and aims to provide a mite repellent composition and a mite repellent product which have excellent mite repellent effect against indoor dust mites even after a long period of time has passed, and which are also safe for humans and animals. [Means for solving the problem]

[0007] The characteristic configuration of the mite repellent composition according to the present invention for solving the above problems is as follows: (a) 1,8-cineole and / or 1,4-cineole, (b) a fragrance ingredient; and A mite repellent composition comprising: The fragrance component contains one or more fragrance compounds having a logP value of 2.0 to 5.5.

[0008] The mite repellent composition of this configuration is formulated to contain (b) a fragrance component in addition to (a) 1,8-cineole and / or 1,4-cineole. Here, the fragrance component contains one or more fragrance compounds having a logP value of 2.0 to 5.5. Therefore, the excellent mite repellent effect against house dust mites due to the relatively highly volatile (a) 1,8-cineole and / or 1,4-cineole can be sustained for a long period of time by the fragrance compound having a logP value of 2.0 to 5.5 contained in (b). In addition, since the (a) and (b) components are excellent in safety for humans and animals, the mite repellent composition can be realized to have high safety.

[0009] In the mite repellent composition according to the present invention, The blending ratio (a / b) of the flavor compound contained in the component (a) to the flavor compound contained in the component (b) is preferably set to 5 to 100 on a mass basis.

[0010] According to the mite repellent composition of this configuration, the blending ratio (a / b) of the fragrance compounds contained in component (a) and component (b) is set within an appropriate range, so that it is possible to achieve both excellent mite repellent effect against house dust mites and high safety for humans and animals.

[0011] In the mite repellent composition according to the present invention, The fragrance compound contained in component (b) is preferably at least one selected from the group consisting of ethyl cinnamate, allyl caproate, 3-methyl-5-phenyl-1-pentanol, citronellol, δ-dodecalactone, β-ionone, benzyl benzoate, linalyl acetate, geranyl acetate, tricyclodecenyl propionate, benzyl salicylate, limonene, and amyl salicylate.

[0012] According to the mite repellent composition of the present invention, since an appropriate fragrance compound is selected for inclusion in component (b), the excellent mite repellent effect of component (a) can be stably maintained for a long period of time.

[0013] The characteristic configuration of the mite repellent product according to the present invention for solving the above problems is as follows: A solid carrier containing any one of the above mite repellent compositions; A breathable packaging material for storing or packaging the solid carrier; The purpose of the present invention is to include the following.

[0014] According to the mite repellent product of this configuration, a solid carrier containing the mite repellent composition of the present invention is stored or packaged in a breathable packaging material, so that a mite repellent product can be realized that is low cost yet has excellent mite repellent effect against indoor dust mites and is highly safe for humans and animals.

[0015] In the mite repellent product according to the present invention, The solid carrier is preferably in the form of particles having an average particle size of 1 to 8 mm.

[0016] According to the mite repellent product of this configuration, since the average particle diameter of the solid carrier is appropriately adjusted, the mite repellent composition can be volatilized stably from the solid carrier for a long period of time. In addition, the mite repellent product can be easy to use and highly practical.

[0017] In the mite repellent product according to the present invention, The solid carrier preferably contains 20 to 400 mg of the component (a) per 1 g.

[0018] According to the mite repellent product of the present composition, since the solid carrier contains an appropriate amount of component (a), it is possible to exhibit excellent mite repellent effect against house dust mites while maintaining a high level of safety. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0019] The mite repellent composition and mite repellent product of the present invention will be described below. However, the present invention is not intended to be limited to the configurations and examples described below.

[0020] <Mite repellent composition> The mite repellent composition of the present invention contains 1,8-cineole and / or 1,4-cineole (component (a)) and a fragrance component (component (b)). Here, component (b) contains at least one fragrance compound having a logP value of 2.0 to 5.5, as described below.

[0021] [Component (a)] 1,8-cineole and / or 1,4-cineole used as the component (a) act as a mite repellent component. 1,8-cineole is a substance contained in eucalyptus essential oil, and 1,4-cineole is a substance contained in Limonium littoralis essential oil, and both have a refreshing scent. 1,8-cineole and 1,4-cineole are generally known as cough suppressants and antiviral agents, and are considered to be low-toxic, non-irritating, and non-sensitizing to humans. In addition, as described in the Background Art section, 1,8-cineole and 1,4-cineole are relatively highly volatile, so when used as a mite repellent component, it has been considered difficult to maintain the mite repellent effect for a long period of time of 2 to 3 months or more.

[0022] However, the present inventors have intensively studied the adjustment of the volatility of a mite repellent composition containing 1,8-cineole and / or 1,4-cineole as component (a), and have found that by blending a fragrance compound having a logP value of 2.0 to 5.5 contained in component (b) described below, the volatility of 1,8-cineole and / or 1,4-cineole can be effectively adjusted, and excellent mite repellent effect against house dust mites can be obtained even after a long period of time has passed. Furthermore, the mite repellent composition of the present invention is highly safe for humans and animals, and is therefore extremely practical and useful.

[0023] The mite repellent composition of the present invention is prepared by adding various ingredients to the component (a) and the component (b) described below, and can be applied to various types of mite repellent products. The amount of the component (a) to be blended with respect to the total amount of the mite repellent product varies depending on the type of the mite repellent product, but is preferably set to about 0.02 to 1.0 g per mite repellent product, and in the case of pillows and cushions, it is easy to use one application. In the case of large bedding such as futons and mats, the number of applications may be appropriately increased as necessary. In the present invention, the component (a) may be 1,8-cineole or 1,4-cineole alone, or eucalyptus essential oil or Limonium littoralis essential oil containing a large amount of these may be used as the active ingredient. For example, eucalyptus essential oil containing 70% by mass or more of 1,8-cineole is widely available as a commercial product. Although it is possible to use a mixture of 1,8-cineole and 1,4-cineole as component (a), it is preferable to use 1,8-cineole from the viewpoint of mite repellent effect.

[0024] The blending amount of component (a) in the mite repellent composition is preferably from 10 to 90 mass %, and more preferably from 20 to 85 mass %.

[0025] [(b) component] The fragrance component used as the (b) component acts as a volatilization control component. Here, the (b) component contains one or more fragrance compounds having a logP value of 2.0 to 5.5. That is, the fragrance component includes not only one type of fragrance compound, but also those containing two or more types of fragrance compounds. When the fragrance component contains one type of fragrance compound, the logP value of the fragrance compound is 2.0 to 5.5. When the fragrance component contains two or more types of fragrance compounds, it is preferable that each of the fragrance compounds has a logP value of 2.0 to 5.5, but it is sufficient that at least one type of fragrance compound has a logP value of 2.0 to 5.5. By blending the (b) component containing a fragrance compound having a logP value of 2.0 to 5.5 in the mite repellent composition, the volatility of the (a) component can be effectively adjusted, and excellent mite repellent effect against house dust mites can be exhibited even after a long period of time. The logP value of the fragrance compound contained in the (b) component is preferably in the range of 3.0 to 5.0. Here, the logP value is a coefficient indicating the affinity of an organic compound to water and 1-octanol. The 1-octanol / water partition coefficient P is the distribution equilibrium when a trace amount of a compound is dissolved as a solute in a two-phase solvent of 1-octanol and water, and is the ratio of the equilibrium concentrations of the compound in each solvent, and is generally expressed in the form of their logarithm logP to the base 10. Note that the logP values ​​described in this specification are not actual measured values, but calculated values ​​calculated using a dedicated application (Advanced Chemistry Development (ACD / Labs) Software V11.02).

[0026] The fragrance compound contained in component (b) having a logP value of 2.0 to 5.5 is not particularly limited, but a monocyclic or chain fragrance compound can be used. Examples of fragrance compounds having a logP value of 2.0 to 5.5 include the following. The number in [ ] after the fragrance compound indicates the logP value.

[0027] Alcohol-based fragrance compounds such as eugenol [2.4], α-terpineol [2.7], linalool [2.8], geraniol [2.9], 3-methyl-5-phenyl-1-pentanol [3.2], citronellol [3.2], phenylhexanol [3.4], and tetrahydrolinalool [3.5]; methyl cinnamate [2.5], γ-decalactone [2.5], and dihydrolinalool [3.6]. Methyl drojasmonate [2.6], ethyl benzoate [2.6], cinnamyl acetate [2.6], hexyl acetate [2.8], ethyl cinnamate [3.0], γ-undecalactone [3.0], δ-undecalactone [3.0], tricyclodecenyl acetate [3.1], allyl caproate [3.1], benzyl phenylacetate [3.5], γ-dodecalactone [3.5], δ-dodecalactone [3.5] Calactone [3.5], benzyl cinnamate [3.8], benzyl benzoate [3.8], linalyl acetate [3.9], geranyl acetate [3.9], 2-phenylethyl phenylacetate [3.9], tricyclodecenyl propionate [4.0], benzyl salicylate [4.2], cyclohexyl salicylate [4.5], amyl salicylate [4.6], hexyl salicylate [5.1] Examples of fragrance compounds include ester-based fragrance compounds such as pentalide [5.2], ketone-based fragrance compounds such as β-damascone [3.3], α-damascone [3.4], β-ionone [3.6], and α-ionone [3.7], aldehyde-based fragrance compounds such as amylcinnamic aldehyde [4.4] and hexylcinnamic aldehyde [4.9], and hydrocarbon-based fragrance compounds such as limonene [4.6].Among these, the following fragrance compounds are monocyclic or chain-type fragrance compounds with logP values ​​of 3.0 or more and 5.0 or less: 3-methyl-5-phenyl-1-pentanol [3.2], citronellol [3.2], phenylhexanol [3.4], tetrahydrolinalool [3.5], ethyl cinnamate [3.0], γ-undecalactone [3.0], δ-undecalactone [3.0], tricyclodecane acetate [3.0], and ethyl cinnamate [3.0]. Cenyl [3.1], allyl caproate [3.1], benzyl phenylacetate [3.5], gamma-dodecalactone [3.5], delta-dodecalactone [3.5], benzyl cinnamate [3.8], benzyl benzoate [3.8], linalyl acetate [3.9], geranyl acetate [3.9], 2-phenylethyl phenylacetate [3.9], tricyclodecenyl propionate [4.0], benzyl salicylate [4.2], salicylate It is preferable that the cyclohexyl licylate [4.5], amyl salicylate [4.6], β-damascone [3.3], α-damascone [3.4], β-ionone [3.6], α-ionone [3.7], amyl cinnamic aldehyde [4.4], hexyl cinnamic aldehyde [4.9] and limonene [4.6] are one or more selected from the group consisting of ethyl cinnamate [3.0] and aryl caproate. Preferred are benzoyl [3.1], 3-methyl-5-phenyl-1-pentanol [3.2], citronellol [3.2], δ-dodecalactone [3.5], β-ionone [3.6], benzyl benzoate [3.8], linalyl acetate [3.9], geranyl acetate [3.9], tricyclodecenyl propionate [4.0], benzyl salicylate [4.2], limonene [4.6], and amyl salicylate [4.6]. These fragrance compounds may be used alone or in a mixture of two or more kinds.

[0028] Incidentally, the logP value of 1,8-cineole and / or 1,4-cineole used as component (a) is 1,8-cineole [2.8] and 1,4-cineole [2.4]. The logP values ​​of these components (a) and the logP values ​​of the fragrance compounds contained in the above-mentioned component (b) are partially overlapping or close to each other, so that the components (a) and (b) are compatible at the molecular level. This is presumably the reason why the component (b) containing the above-mentioned fragrance compounds effectively adjusts the volatility of the component (a), and provides the effect of the present invention in that the compound has an excellent mite repellent effect against house dust mites such as flour mites, house dust mites, dust mites, and chiggers even after a long period of time.

[0029] The blending amount of the fragrance compound contained in component (b) in the mite repellent composition is preferably from 0.01 to 20 mass %, and more preferably from 0.1 to 10 mass %.

[0030] The blending ratio (a / b) of the fragrance compounds contained in the component (a) and the component (b) is preferably set to 5 to 100 on a mass basis, and more preferably set to 5 to 80. When the blending ratio (a / b) is within the above range, the volatility of the 1,8-cineole and / or 1,4-cineole (a) can be effectively adjusted, and an excellent mite repellent effect against house dust mites can be exhibited even after a long period of time while ensuring high safety. Therefore, it is possible to achieve both an excellent mite repellent effect against house dust mites and high safety for humans and animals.

[0031] [Other ingredients] In addition to the above-mentioned components (a) and (b), the mite repellent composition of the present invention may contain various solvents such as alcohol-based solvents such as water, ethanol, and isopropanol, glycol-based solvents such as 1,3-butylene glycol, propylene glycol, and dipropylene glycol, glycol ether-based solvents such as diethylene glycol monobutyl ether and propylene glycol monomethyl ether, and aliphatic hydrocarbon-based solvents such as normal paraffin and isoparaffin, as well as surfactants (solubilizers).The mite repellent composition of the present invention may also be prepared without adding other components such as solvents in addition to the above-mentioned components (a) and (b).

[0032] Examples of the surfactant include nonionic surfactants such as polyoxyethylene hydrogenated castor oil, polyoxyethylene higher alkyl ethers (polyoxyethylene lauryl ether, polyoxyethylene oleyl ether), polyoxyethylene higher fatty acid esters, polyoxyethylene polyoxypropylene alkyl ethers, and higher alkylamine oxide surfactants such as laurylamine oxide, stearylamine oxide, and lauric acid amidopropyl dimethylamine oxide. The above surfactants may be used alone or as a mixture of two or more of them.

[0033] The mite repellent composition of the present invention may also be appropriately blended with antibacterial components, antifungal components, deodorant components, fragrance components, insecticidal components, repellent components, stabilizers, pH adjusters, colorants, gelling agents, etc. Furthermore, for example, leaf alcohol (cis-3-hexen-1-ol) and leaf aldehyde, which are known as the "green scent," may also be added, which can impart a relaxing effect and promote sound sleep.

[0034] Examples of antibacterial components include phenolic antibacterial components such as isopropylmethylphenol (IPMP), carvacrol, thymol, triclosan, methylparaben, ethylparaben, propylparaben, butylparaben, 4-chloro-3,5-dimethylphenol, orthophenylphenol, o-cresol, m-cresol, and p-cresol; benzalkonium salts such as benzalkonium chloride, benzalkonium methosulfate, and benzalkonium organic acid salts; benzethonium salts such as benzethonium chloride, benzethonium methosulfate, and benzethonium organic acid salts; cetylpyridinium salts such as cetylpyridinium chloride, cetylpyridinium methosulfate, and cetylpyridinium organic acid salts; didecyldimethylammonium salts such as didecyldimethylammonium chloride and didecyldimethylammonium methosulfate; dilauryldimethylammonium salts such as dilauryldimethylammonium chloride and dilauryldimethylammonium methosulfate; distearyldimethylammonium chloride, distearyldimethylammonium chloride, distearyldimethylammonium salts such as 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dibromide, 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dichloride, 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dimethosulfate and other cationic surfactant-based antibacterial ingredients such as 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane salts such as 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dimethosulfate; biguanide-based antibacterial ingredients; tebuconazole, enilconazole, antibacterial ingredients such as azole, fruit seed extract-based antibacterial ingredients such as grapefruit seed extract, oyster seed extract, grape seed extract, etc., glycerin mono fatty acid ester-based antibacterial ingredients such as monolaurin, monocaprin, monocaprylin, etc., chlorhexidine salts such as chlorhexidine gluconate and chlorhexidine hydrochloride, chlorhexidine-based antibacterial ingredients such as chlorhexidine, octadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride,Dodecyldiisopropyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride, hexadecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, hexadecyldiethyl(3-triethoxysilylpropyl)ammonium Examples of the antibacterial components include silicon-based antibacterial components such as ammonium chloride, hexadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, and octadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride; carboxylic acid-based antibacterial components such as benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyl diethylaminoglycine, and polylysine, or salts thereof; dehydroacetic acid, chloramine, 3-iodo-2-propyl-N-butylcarbamate (IPBC), phenoxyethanol, and silver-based antibacterial components such as silver zeolite; zinc pyrithione, thiamine lauryl sulfate, milt protein, and hydroxyalkyl chitosan or salts thereof. The above antibacterial components may be used alone or as a mixture of two or more kinds.

[0035] Examples of the antifungal component include phenolic antifungal components such as isopropylmethylphenol (IPMP), carvacrol, thymol, triclosan, methylparaben, ethylparaben, propylparaben, butylparaben, 4-chloro-3,5-dimethylphenol, orthophenylphenol, o-cresol, m-cresol, and p-cresol; benzalkonium salts such as benzalkonium chloride, benzalkonium methosulfate, and benzalkonium organic acid salts; benzethonium chloride, benzethonium methosulfate, and the like. benzethonium salts such as cetylpyridinium chloride, cetylpyridinium methosulfate, cetylpyridinium organic acid salts, cetylpyridinium salts such as cetylpyridinium chloride, cetyldimethylammonium salts such as didecyldimethylammonium chloride, didecyldimethylammonium methosulfate, dilauryldimethylammonium salts such as dilauryldimethylammonium chloride, dilauryldimethylammonium methosulfate, distearyldimethylammonium chloride, distearyldimethylammonium Distearyl dimethyl ammonium salts such as 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dibromide, 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dichloride, 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dimethosulfate and other cationic surfactant-based antifungal ingredients such as 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane salts such as 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dimethosulfate, biguanide-based antifungal ingredients, tebuconazole, enilconazole antifungal ingredients such as azole-based antifungal ingredients such as benzoyl, fruit seed extract-based antifungal ingredients such as grapefruit seed extract, oyster seed extract, grape seed extract, etc.; antifungal ingredients such as glycerin mono fatty acid ester-based antifungal ingredients such as monolaurin, monocaprin, monocaprylin, etc.; antifungal ingredients such as chlorhexidine salts such as chlorhexidine gluconate and chlorhexidine hydrochloride, and chlorhexidine-based antifungal ingredients such as chlorhexidine; octadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride,Dodecyldiisopropyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride, hexadecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, hexadecyldiethyl(3-triethoxysilylpropyl)ammonium Examples of the antifungal agents include silicon-based antifungal agents such as hexadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, and octadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride; carboxylic acid-based antifungal agents such as benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyl diethylaminoglycine, and polylysine, or salts thereof; dehydroacetic acid, chloramine, 3-iodo-2-propyl-N-butylcarbamate (IPBC), phenoxyethanol, and silver-based antifungal agents such as silver zeolite; zinc pyrithione, thiamine lauryl sulfate, milt protein, hydroxyalkyl chitosan or its salt, and antifungal fragrances. The above antifungal agents may be used alone or as a mixture of two or more.

[0036] Examples of deodorizing components include plant-derived deodorizing components. Examples of plant-derived deodorizing components include plant extracts extracted from plants of the Poaceae, Theaceae, Ginkgoaceae, Oleaceae, Mulberry, Rutaceae, Cantharinaceae, Ebenaceae, etc. The above plant extracts may be used alone or as a mixture of two or more kinds, and representative examples include green tea extract and persimmon extract.

[0037] Examples of gelling agents include carrageenan, xanthan gum, gellan gum, gelatin, aluminum octylate, 12-hydroxystearic acid, etc. The above gelling agents may be used alone or as a mixture of two or more kinds.

[0038] <Mite repellent products> The mite repellent product of the present invention contains the above-mentioned mite repellent composition of the present invention, and can be prepared in various forms such as solid, liquid, gel, etc. according to the scene of use and the needs of consumers. Among them, a product form in which the mite repellent composition is impregnated or held in a solid carrier and stored or packaged in a breathable material is preferable. Such a mite repellent product can be realized at low cost, with excellent mite repellent effect against indoor dust mites and high safety for humans and animals, simply by placing it under or near a pillow, cushion, or futon, mat, etc., and the mite repellent component effectively volatilizes from the solid carrier.

[0039] Examples of solid carriers include pulps such as cellulose pulp, linters, rayon, and other fibrous carriers, cellulose (regenerated cellulose) beads or foams, inorganic porous carriers such as silicates, silica, zeolites, and sublimable carriers such as trioxane, adamantane, etc. Among these, pulps such as cellulose pulp, linters, rayon, and other fibrous carriers, and cellulose (regenerated cellulose) beads are preferred, and cellulose pulp is more preferred.

[0040] When the solid carrier is a bead (granule), its average particle size is usually 1 to 8 mm, preferably 3 to 8 mm, and more preferably 4 to 7 mm. The apparent specific gravity of the solid carrier is usually about 0.10 to 0.35, and preferably 0.15 to 0.30. For example, by adding about 20 to 400 mg, preferably 30 to 300 mg, of the (a) 1,8-cineole and / or 1,4-cineole per gram of cellulose pulp and storing it in an air-permeable packaging material, a useful and highly practical mite repellent product of the present invention can be obtained.

[0041] Examples of breathable packaging materials include nonwoven bags, cotton bags, net cases, and perforated plastic containers. Among these, nonwoven bags are preferred in terms of ease of use. Examples of materials for nonwoven bags include polyester (PET), polyethylene (PE), polypropylene (PP), polyamide, polylactic acid, and rayon. The nonwoven bag may be made of a single fiber, or may be a laminate or blend such as polyester laminated with paper or polypropylene / rayon. Among these, polyester, polyethylene, and polypropylene are preferred in that the amount of volatilization of the (a) 1,8-cineole and / or 1,4-cineole can be secondarily adjusted by partially adsorbing the 1,8-cineole and / or 1,4-cineole. The shape and configuration of the nonwoven bag can also be appropriately determined. For example, both sides may be made of nonwoven fabric of the material, or one side may be made of nonwoven fabric of the material and the other side may be made of a plastic film having a large number of small holes, and these may be bonded together.

[0042] The application location of the mite repellent product of the present invention thus obtained is not particularly limited, but it can be installed under or near carpets, tatami mats, pillows, cushions, futons, mats, etc., and is particularly suitable for use as bedding such as pillows, cushions, futons, and mats. If it is installed under or near a pillow, cushion, or futon or mat, the mite repellent component will volatilize from the solid carrier through the breathable material, and will have a practical repellent effect for a long period of 1 month to 6 months against various pests such as weevils, dermestid beetles, booklice, beetles, cockroaches, ants, mosquitoes, moths, midges, flies, moths, and burrs, as well as house dust mites such as flour mites, house dust mites, dust mites, and cheyletids. The mite repellent product of the present invention can effectively exert a repellent effect against house dust mites such as flour mites, house dust mites, dust mites, and cheyletids. EXAMPLES

[0043] The present invention will now be described in detail with reference to examples.

[0044] Example 1 A mite repellent composition was prepared by mixing 400 mg of 1,8-cineole as component (a) and 8 mg of 3-methyl-5-phenyl-1-pentanol as component (b). The entire amount of this mite repellent composition was impregnated into approximately 8 g of cellulose pulp granules with an average particle size of 5.5 mm and an apparent specific gravity of 0.21. The cellulose pulp granules impregnated with the mite repellent composition were then placed in a nonwoven bag (9 x 12 cm) made of a breathable polyethylene / polypropylene blend nonwoven fabric on both sides, to obtain the mite repellent product of Example 1.

[0045] [Examples 2 to 11, Comparative Examples 1 to 2, Reference Examples 1 to 3] A mite repellent composition containing components (a) and (b) in the formulation shown in Table 1 was prepared in accordance with Example 1, and various mite repellent products of Examples 2 to 11, Comparative Examples 1 and 2, and Reference Examples 1 to 3 were obtained using the same procedures as in Example 1.

[0046] [Table 1]

[0047] [Mite repellent efficacy test] Each of the mite repellent products of Examples 1 to 11, Comparative Examples 1 to 2, and Reference Examples 1 to 3 was wrapped in a wool blanket, a 4 kg weight was placed on top of it, and left to stand at room temperature for 2 months, after which each mite repellent product was collected.

[0048] Next, a medium containing about 100,000 test Dermatophagoides pteronyssinus was evenly spread in the center of a 50 cm square cotton cloth. Each of the above-mentioned mite repellent products after two months of standing was placed on a pillow and covered with a pillowcase, 1 g of the attractant medium was spread on the surface, and the pillow was placed in the center of the cotton cloth, which was used as a treatment area. The same operation was also performed using a pillow without the mite repellent product, which was used as a non-treatment area. Then, the number of mites that had invaded the pillowcase after 24 hours was counted, and the mite repellent effect (repellency rate) was calculated according to the following formula. Mite repellency (%) = (N0-N1) / N0 x 100 N0: Number of invaded mites in the untreated area N1: Number of invaded mites in the treated area

[0049] The results of the mite repellent efficacy test are shown in Table 2.

[0050] [Table 2]

[0051] It was found that all of the mite repellent products of Examples 1 to 11 exhibited excellent mite repellent effects of 80% or more even after two months. This is thought to be because the component (b) containing a fragrance compound with a logP value of 2.0 to 5.5 effectively regulated the volatilization of (a) 1,8-cineole and / or 1,4-cineole, which is why the mite repellent products of Examples 1 to 11 achieved excellent mite repellent effects even after a long period of time. Among them, the mite repellent products of Examples 1, 3 to 7, 10, and 11, which contained (a) 1,8-cineole and the component (b) containing a fragrance compound with a logP value of 3.0 to 5.0, all exhibited mite repellent effects of 85% or more even after two months, and were found to be more excellent.

[0052] On the other hand, the mite repellent product of Reference Example 1, which contains cyclohexadecanolide (logP value: 5.7) with a logP value of more than 5.5 as component (b), and the mite repellent product of Reference Example 2, which contains butyl acetate (logP value: 1.8) with a logP value of less than 2.0, showed a decreased mite repellent effect after a long period of time compared to the mite repellent products of Examples 1 to 11. This is probably due to the fact that the volatile control of 1,8-cineole is somewhat poor in fragrance compounds with logP values ​​outside the range of 2.0 to 5.5. Comparing Examples 1 to 11 and Reference Examples 1 to 3, it was found that the mite repellent effect after a long period of time can be further improved by adding component (b) containing a fragrance compound with a logP value of 2.0 to 5.5 to (a) 1,8-cineole and / or 1,4-cineole.

[0053] Moreover, the mite repellent products of Comparative Examples 1 and 2, which contained other citronellal or vetiver oil as component (a), showed insufficient mite repellent effect after a long period of time, even when they contained component (b) containing a fragrance compound with a logP value of 2.0 to 5.5. From this, it is considered that the phenomenon in which the fragrance compound with a logP value of 2.0 to 5.5 contained in component (b) effectively regulates the volatilization of the pest repellent component is specific to (a) 1,8-cineole and / or 1,4-cineole. [Industrial Applicability]

[0054] The mite repellent composition and mite repellent product of the present invention can be suitably used for repelling indoor dust mites that lurk in bedding (mite repellent composition and mite repellent product for bedding), but can naturally also be used for repelling a wide range of pests in addition to indoor dust mites.

Claims

1. (a) 1,8-cineole and / or 1,4-cineole, (b) a fragrance ingredient; and A mite repellent composition comprising: The component (b) contains one or more fragrance compounds having a log P value of 2.0 to 5.5, The fragrance compound contained in the component (b) is citronellol and / or geranyl acetate, The blending ratio (a / b) of the fragrance compound contained in the component (a) to the fragrance compound contained in the component (b) is A mite repellent composition set at 5 to 100 on a mass basis (excluding those containing 3-(3,4-methylenedioxyphenyl)-2-methylpropanal and / or 3,4-methylenedioxybenzaldehyde).

2. (a) 1,8-cineole and / or 1,4-cineole, (b) a fragrance ingredient; and A mite repellent composition comprising: The component (b) contains one or more fragrance compounds having a log P value of 2.0 to 5.5, The fragrance compound contained in the component (b) is limonene, The blending ratio (a / b) of the fragrance compound contained in the component (a) to the fragrance compound contained in the component (b) is A mite repellent composition set at 5 to 80 on a mass basis (excluding those containing 3-(3,4-methylenedioxyphenyl)-2-methylpropanal and / or 3,4-methylenedioxybenzaldehyde).

3. A solid carrier containing the mite repellent composition according to claim 1 or 2; A breathable packaging material for storing or packaging the solid carrier; Tick ​​repellent products, including:

4. 4. The mite repellent product according to claim 3, wherein the solid carrier is a granular material having an average particle size of 1 to 8 mm.

5. 5. The mite repellent product according to claim 3, wherein the solid carrier contains 20 to 400 mg of the component (a) per gram.

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