Active compound combinations and antifungal compositions containing them - Patents.com

Abstract

The present invention relates to active compound combinations comprising methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid or mixtures thereof and at least one further specific antifungal agent, as well as compositions comprising such compound combinations and their use as bioactive agents for the control of harmful microorganisms, in particular in crop protection and the protection of industrial materials.

Description

[Technical field]

[0001] The present invention relates to an active compound combination comprising methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid or mixtures thereof as compound (A), a further specific antifungal agent as compound (B) and, optionally, one or more further antifungal agents as compound (C).Furthermore, the present invention relates to an antifungal composition comprising such a compound combination and to the use of said compound combination and said antifungal composition as bioactive agent and as plant growth regulator for the control of phytopathogenic fungi, in particular in crop protection and in the protection of industrial materials. [Background technology]

[0002] Throughout this specification, the terms "composition" and "formulation" are used interchangeably to refer to a mixture of a compound combination of the present invention and at least one agriculturally suitable adjuvant.

[0003] Methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate and 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, their preparation and the antifungal effect of said compounds are known from WO 2019 / 093522 (A1). WO 2019 / 093522 (A1) further discloses compositions comprising at least one of said compounds, as well as active compound combinations further comprising at least one of said compounds and at least one further active ingredient, in particular a further antifungal agent. Antifungal agents for agricultural or horticultural applications comprising at least one of said compounds and at least one specific further active ingredient are known from WO 2020 / 213739 (A1).

[0004] The known compound combinations comprising methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid and any of these compounds provide an excellent means of protecting plants from diseases caused by fungi. However, there is still a need to further improve these means to address the ever-increasing environmental and economic demands imposed on modern crop protection agents and compositions. This includes, for example, improvements in spectrum of action, safety profile, selectivity, application rate, residue generation, and favorable formulation capabilities, as well as the development of new compositions to address potential issues such as resistance. Summary of the Invention

[0005] The present invention provides active compound combinations and compositions comprising said combinations that achieve at least to some extent the stated objectives. Thus, the present invention provides (A) as compound (A), methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid or a mixture thereof; (B) As the compound (B), (1) (1.009) Fluoxythioconazole, (1.014) Imazalil sulfate, (1.032) (1R,2S,5S)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.033) (1S,2R,5R)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.034) (2R)-2-(1-chlorocyclopropyl)-4-[(1R)-2,2-dichlorocyclopropyl]-1-( 1H-1,2,4-triazol-1-yl)butan-2-ol, (1.035)(2R)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.036)(2R)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol, (1.037)(2S)-2-(1-chlorocyclopropyl)-4-[(1R )-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.038)(2S)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.039)(2S)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol, (1.040)(R)-[3 -(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.041)(S)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.042)[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.043) 1-({(2R,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole, (1.044) 1-({(2S,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole, (1.045) 1-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl Thiocyanate, (1.046) 1-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl thiocyanate, (1.047) 1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl thiocyanate, (1.048) 2-[(2R,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione,. (1.049) 2-[(2R,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.050) 2-[(2R,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.051) 2-[(2R,4S,5S)-1-(2,4-dichlorophenyl) -5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.052) 2-[(2S,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.053) 2-[(2S,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro 3H-1,2,4-triazole-3-thione, (1.054) 2-[(2S,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.055) 2-[(2S,4S,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.056) 2-[1-( 2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.057) 2-[6-(4-bromophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol, (1.058) 2-[6-(4-chlorophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol, (1.059) 2-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.060) 2-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.061) 2-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione (1.062) 3-[2-(1-chlorocyclopropyl)-3-(3-chloro-2-fluoro-phenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile, (1.063) 5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.064) 5-(arylsulfanyl)-1-{[3- (2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole, (1.065) 5-(arylsulfanyl)-1-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole, (1.066) 5-(arylsulfanyl)-1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran- 2-yl]methyl}-1H-1,2,4-triazole, (1.068) N'-(2-chloro-5-methyl-4-phenoxyphenyl)-N-ethyl-N-methylimidoformamide, (1.069) N'-[2-chloro-4-(2-fluorophenoxy)-5-methylphenyl]-N-ethyl-N-methylimidoformamide, (1.070) N'-[5-bromo-6-(2,3-dihydro-1H-inden-2-yloxy)-2-methylpyridin-3-yl]-N-ethyl-N-methylimidoformamide, (1.071) N'-{4-[(4,5-dichloro-1,3-thiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylimidoformamide, (1.073) N'-{5-bromo-6-[(1R)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.074) N'-{5-bromo-6-[(1S)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.075) N'-{5-bromo-6-[(cis-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl an inhibitor of ergosterol synthesis selected from the group consisting of N'-{5-bromo-6-[(trans-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.076) N'-{5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.077) N'-{5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.078) N-isopropyl-N'-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-phenylethyl)phenyl]-N-methylimidoformamide. (2) (2.005) cyclobutrifluram, (2.006) fulveneteram, (2.023) 1,3-dimethyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide, (2.024) 1,3-dimethyl-N-[(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2.025) 1,3-dimethyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden- 4-yl]-1H-pyrazole-4-carboxamide, (2.026) 1-methyl-3-(trifluoromethyl)-N-[2'-(trifluoromethyl)biphenyl-2-yl]-1H-pyrazole-4-carboxamide, (2.027) 2-fluoro-6-(trifluoromethyl)-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)benzamide, (2.028) 3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole 3-(Difluoromethyl)-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2.029) 3-(difluoromethyl)-1-methyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2.030) 3-(difluoromethyl)-N-[(3R)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.031) 3-(difluoromethyl)-N-[(3S)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.032) 5,8-difluoro-N-[2-(2-fluoro-4-{[4-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)ethyl]quinazolin-4-amine, (2.033) N-[(1R,4S)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.034) Inhibitors of the respiratory chain in complex I or II selected from the group consisting of N-[(1S,4R)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.035) N-[1-(2,4-dichlorophenyl)-1-methoxypropan-2-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.036) N-[rac-(1S,2S)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)nicotinamide. (3) (3.005) Methoxystrobin, (3.017) Methallylpicoxamide, (3.023) Pyrametstrobin, (3.026) (2E)-2-{2-[({[(1E)-1-(3-{[(E)-1-fluoro-2-phenylvinyl]oxy}phenyl)ethylidene]amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide, (3.027) (2E,3Z)-5-{[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.028) (2R)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide inhibitors of the respiratory chain in complex III selected from the group consisting of (2S)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide, (3.029) (2S)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide, (3.030) N-(3-ethyl-3,5,5-trimethylcyclohexyl)-3-formamido-2-hydroxybenzamide, (3.031) (2E,3Z)-5-{[1-(4-chloro-2-fluorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.032) methyl{5-[3-(2,4-dimethylphenyl)-1H-pyrazol-1-yl]-2-methylbenzyl}carbamate, (4) (4.013) 3-chloro-5-(4-chlorophenyl)-4-(2,6-difluorophenyl)-6-methylpyridazine, (4.014) 3-chloro-5-(6-chloropyridin-3-yl)-6-methyl-4-(2,4,6-trifluorophenyl)pyridazine, (4.015) 4-(2-bromo-4-fluorophenyl)-N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.016) 4-(2-bromo-4-fluorophenyl)-N-(2-bromo-6-fluorophenyl)- (4.017) 4-(2-bromo-4-fluorophenyl)-N-(2-bromophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.018) 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.019) 4-(2-bromo-4-fluorophenyl)-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.020) 4-(2-bromo-4-fluorophenyl)-N-(2-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.021) 4-(2-chloro-4-fluorophenyl)-N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.022) 4-(2-chloro-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.023) 4-(2-chloro-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, )-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.024) 4-(2-chloro-4-fluorophenyl)-N-(2-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.025) 4-(4-chlorophenyl)-5-(2,6-difluorophenyl)-3,6-dimethylpyridazine, (4.026) N-(2-bromo-6-fluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.027) Inhibitors of mitosis and cell division selected from the group consisting of N-(2-bromophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.028) N-(4-chloro-2,6-difluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine. (5) Compounds capable of having a multi-site action selected from the group consisting of (5.001) Bordeaux mixture, (5.005) copper hydroxide, (5.006) copper naphthenate, (5.007) copper oxide, (5.008) copper oxychloride, (5.009) copper(2+) sulfate, (5.016) zinc metiram, (5.017) copper oxine, (5.019) sulfur preparations containing calcium polysulfide, (5.023) 6-ethyl-5,7-dioxo-6,7-dihydro-5H-pyrrolo[3',4':5,6][1,4]dithiino[2,3-c][1,2]thiazole-3-carbonitrile; (6) Compounds capable of inducing host defense selected from the group consisting of (6.003) fosetyl calcium, (6.004) fosetyl sodium, (6.008) tiadinil; (7) (7.003) Inhibitors of amino acid and / or protein biosynthesis selected from the group consisting of kasugamycin hydrochloride hydrate; (9) (9.008) (2E)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-1-(morpholin-4-yl)prop-2-en-1-one, (9.009) (2Z)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-1-(morpholin-4-yl)prop-2-en-1-one, (10) (10.005) Propamocarb hydrochloride, (10.006) Propamocarb fosethylate, (10.008) 1-(4-{4-[(5R)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone, (10.009) 1-(4-{4-[(5S)-5-(2,6-difluorophenyl)- 4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone, (10.010) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidine 10.011) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-chloro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.012) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-fluoro-6 -(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.013) 2-{(5R)-3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate, (10.014) Methanesulfonic acid 2-{(5S)-3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl (10.015) Methanesulfonic acid 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl 3-[2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl]methanesulfonate; (10.017) methanesulfonate; 9-Fluoro-3-[2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl sulfonate, (10.018) 3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate ,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl, (10.019) inhibitors of lipid and membrane synthesis selected from the group consisting of 3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-9-fluoro-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (15) (15.001) abscisic acid, (15.003) benzothiazole, (15.004) bethoxazin, (15.005) capsimycin, (15.006) carvone, (15.008) chlorinconazide, (15.009) khuraneb, (15.012) cyprosulfamide, (15.015) flufenoxadiazam, (15.016) flumethylsulfolim, (15.018) methyl isothiocyanate, (15.019) mildiomycin, (15.020) nickel dimethyldithiocarbamate, (15.02 1) Nitroisopropyl tartar, (15.022) Oxyfenthiin, (15.023) Pentachlorophenol and salts, (15.026) D-tagatose, (15.029) Tolnifanide, (15.030) 2-(6-benzylpyridin-2-yl)quinazoline, (15.031) 2-[6-(3-fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline, (15.032) 2-phenylphenol and salts, (15.033) 4-amino-5-fluoropyrimidin-2-ol (tautomer: 4-amino -5-fluoropyrimidin-2(1H)-one), (15.034) 4-oxo-4-[(2-phenylethyl)amino]butanoic acid, (15.035) 5-amino-1,3,4-thiadiazole-2-thiol, (15.036) 5-chloro-N'-phenyl-N'-(prop-2-yn-1-yl)thiophene-2-sulfonohydrazide, (15.037) 5-fluoro-2-[(4-fluorobenzyl)oxy]pyrimidin-4-amine, (15.038) 5-fluoro-2-[(4-methylbenzyl)oxy]pyrimidin-4 -amine, (15.039) but-3-yn-1-yl {6-[({[(Z)-(1-methyl-1H-tetrazol-5-yl)(phenyl)methylene]amino}oxy)methyl]pyridin-2-yl}carbamate, (15.040) ethyl (2Z)-3-amino-2-cyano-3-phenylacrylate, (15.041) phenazine-1-carboxylic acid, (15.042) propyl 3,4,5-trihydroxybenzoate, (15.043) quinolin-8-ol, (15.044) quinolin-8-ol sulfate (2:1), (15.045) 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.046) 1-(5-(fluoromethyl)-6-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.047) 1-(5,6-dimethylpyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.048) 1-(6-(difluoromethyl)-5-methoxy-pyridin-3-yl) -4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.049) 1-(6-(difluoromethyl)-5-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.050) 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.051) 2-{2-fluoro-6-[(8-fluoro-2-methylquinolin-3-yl)oxy]phenyl}propan-2-ol, (15.052) 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.053) 3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-8-fluoroquinoline, (15.054) 3-(4,4-difluoro-5,5-dimethyl-4,5-dihydrothieno[2,3-c]pyridin-7-yl)quinoline, (15.055) 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.056) 5-Bromo-1-(5,6-dimethylpyridin-3-yl)-3,3-dimethyl-3,4-dihydroisoquinoline, (15.057) 8-Fluoro-3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)-quinoline, (15.058) 8-Fluoro-3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-quinoline, (15.059) 8-Fluoro-N-(4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl)quinoline-3-carboxamide, (15.060) 8-Fluoro-N-[(2S)-4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl]quinoline-3-carboxamide, (15.061) 9-Fluoro-2,2-. Dimethyl-5-(quinolin-3-yl)-2,3-dihydro-1,4-benzoxazepine, (15.062) N-(2,4-dimethyl-1-phenylpentan-2-yl)-8-fluoroquinoline-3-carboxamide, (15.063) N-[(2S)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063A) N-[(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063B) 2-benzyl-N-(8-fluoro (15.063C) (2S)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.063D) (2R)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.064) 1,1-diethyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.065) 1,3-dimethoxy-1-[ [4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.066) 1-[[3-fluoro-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl]methyl]azepan-2-one, (15.067) 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.068) 1-methoxy-1-methyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.069) 1-methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.070) 1-methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.071) 2,2-difluoro-N-methyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide, (15.072) 3,3-Dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.073) 3-Ethyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.074) 4,4-Dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.075) 4,4-Dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-. 3-yl]phenyl]methyl]isoxazolidin-3-one, (15.076) 4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl dimethylcarbamate, (15.077) 5,5-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, (15.078) 5-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.079) 1-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}-1H-pyrazoline ethyl 4-carboxylate, (15.080) methyl{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}carbamate, (15.081) N-(1-methylcyclopropyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.082) N-(2,4-difluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.083) N,2-dimethy 15.084) N,N-dimethyl-1-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}-1H-1,2,4-triazol-3-amine; (15.085) N-[(E)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide; (15.086) N-[( E)-N-Methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.087) N-[(Z)-Methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.088) N-[(Z)-N-Methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.089) N-[[2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-3,3,3-trifluoro-propanamide, (15.090) N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.091) N-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]cyclopropanecarboxamide, (15.092) N-{ 2,3-Difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}butanamide, (15.093) N-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}cyclopropanecarboxamide, (15.094) N-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}propanamide, (15.095) N-Allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}propanamide 15.096) N-Allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.097) N-Ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.098) N-Methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide other antifungal agents selected from the group consisting of N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.099) N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.100) N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzenecarbothioamide, (15.101) N-methyl-N-phenyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide. (16) A biological control agent comprising: (A') (A1) (A1.01) Bacillus subtilis, in particular the strain QST713 / AQ713 (available from Bayer CropScience LP, USA as SERENADE OPTI or SERENADE ASO, NRRL Accession No. B21661, U.S. Patent No. 6,060,051); (A1.02) Bacillus sp., in particular the strain D747 (available from Kumiai Chemical Industry Co., Ltd. as DOUBLE NICKEL®), Accession No. FERM BP-8234, U.S. Patent No. 7,094,592; (A1.03) Bacillus pumilus, in particular the strain BU F-33, NRRL Accession No. 50185 (available from BASF as part of the CARTISSA® product, European Registration No. 71840-19); (A1.04) Bacillus subtilis var. amyloliquefaciens strain FZB24 Accession No. DSM10271 (available from Novozymes as TAEGRO® or TAEGRO®, ECO (EPA Registration No. 70127-5)); (A1.05) Paenibacillus sp. strain Accession No. NRRL B-50972 or Accession No. NRRL B-67129, WO 2016 / 154297; (A1.06) Bacillus subtilis strain BU1814, (available from BASF SE as VELONDIS® PLUS, VELONDIS® FLEX and VELONDIS® EXTRA); (A1.07) Bacillus mojavensis strain R3B (Accession No. NCAIM(P)B001389) (WO 2013 / 034938), from Certis USA LLC, a Mitsui & Co. subsidiary; (A1.08) Bacillus subtilis CX-9060, from Certis USA LLC, a Mitsui & Co. subsidiary; (A1.09) Paenibacillus polymyxa, in particular strain AC-1 (e.g. TOPSEED®, from Green Biotech Company Ltd.); (A1.10) Pseudomonas proradix (e.g. PRORADIX®, from Sourcon Padena); (A1.11) Pantoea agglomerans, in particular strain E325 (Accession No. NRRL B-21856) (available from Northwest Agri Products as BLOOMTIME BIOLOGICAL™ FD BIOPESTICIDE), as well as. (A2) (A2.01) Aureobasidium pullulans, in particular blastospores of the strain DSM 14940, blastospores of the strain DSM 14941 or a blastospore mixture of the strains DSM 14940 and DSM 14941 (e.g. BOTECTOR® and BLOSSOM PROTECT® from bio-ferm, Switzerland); (A2.02) Pseudozyma aphidis (disclosed in WO 2011 / 151819 (Yissum Research Development Company, The Hebrew University)); (A2.03) Saccharomyces cerevisiae, in particular the strains CNCM No. I-3936, CNCM No. I-3937, CNCM No. I-3938 or CNCM No. I-3939 (WO 2010 / 086790), Lesaffre et Compagnie, France; An antibacterial agent selected from (B') (B1) (B1.01) Bacillus subtilis, in particular the strain QST713 / AQ713 (available from Bayer CropScience LP, USA as SERENADE OPTI or SERENADE ASO, described in NRRL Accession No. B21661 and U.S. Patent No. 6,060,051); (B1.02) Bacillus pumilus, in particular the strain QST2808 (available from Bayer CropScience LP, USA as SONATA®, described in NRRL Accession No. B-30087 and U.S. Patent No. 6,245,551); (B1.03) Bacillus pumilus, in particular the strain GB34 (available from Bayer CropScience LP, USA as Yield Shield®, described in NRRL Accession No. B-30087 and U.S. Patent No. 6,245,551); AG, Germany; (B1.04) Bacillus pumilus, in particular the strain BU F-33, NRRL accession no. 50185 (available from BASF as part of the CARTISSA range, European registration no. 71840-19); (B1.05) Bacillus amyloliquefaciens, in particular the strain D747 (available from Kumiai Chemical Industry Co., Ltd. as Double Nickel™, accession no. FERM BP-8234, U.S. Patent No. 7,094,592); (B1.06) Bacillus subtilis subtilis Y1336 (available from Bion-Tech, Taiwan as BIOBAC® WP, registered in Taiwan as a biological antifungal agent under registration numbers 4764, 5454, 5096 and 5277); (B1.07) Bacillus subtilis strain MBI600 (available from BASF SE as SUBTILEX), accession number NRRL B-50595, U.S. Patent No. 5,061,495; (B1.08) Bacillus subtilis strain GB03 (available from Bayer AG, Germany as Kodiak®); (B1.09) Bacillus subtilis var. amyloliquefaciens strain FZB24, accession no. DSM10271 (available from Novozymes as TAEGRO® or TAEGRO®, ECO (EPA registration no. 70127-5)); (B1.10) Bacillus mycoides isolate J., accession no. B-30890 (available from Certis USA LLC, a Mitsui & Co. subsidiary as BMJ TGAI® or WG and LifeGard®); (B1.11) Bacillus licheniformis, in particular strain SB3086, accession no. ATCC 55406, WO 2003 / 000051 (available from Novozymes as ECOGUARD® Bio-Antifungal and GREEN RELEAF™); (B1.12) Paenibacillus sp. strain Accession No. NRRL B-50972 or Accession No. NRRL B-67129, WO 2016 / 154297; (B1.13) Bacillus subtilis strain BU1814, (available from BASF SE as VELONDIS® PLUS, VELONDIS® FLEX and VELONDIS® EXTRA); (B1.14) Bacillus subtilis CX-9060, available from Certis USA LLC, Mitsui & Co. Co. subsidiaries; (B1.15) Bacillus amyloliquefaciens strain F727 (also known as strain MBI110) (NRRL Accession No. B-50768; WO 2014 / 028521) (from Marrone Bio Innovations as STARGUS®); (B1.16) Bacillus amyloliquefaciens strain FZB42, Accession No.DSM23117 (available as RHIZOVITAL® from ABiTEP, Germany); (B1.17) Bacillus licheniformis FMCH001 and Bacillus subtilis FMCH002 (from FMC Corporation as QUARTZO® (WG) and PRESENCE® (WP)); (B1.18) Bacillus mojavensis strain R3B (Accession No. NCAIM(P)B001389) (WO 2013 / 034938) from Certis USA LLC, a Mitsui & Co. subsidiary; (B1.19) Paenibacillus polymyxa ssp. plantarum. (B1.20) Paenibacillus epiphyticus (WO 2016 / 020371), from BASF SE; (B1.21) Pseudomonas chlororaphis strain AFS009, Accession No. NRRL B-50897, WO 2017 / 019448 (e.g., from AgBiome Innovations, USA as HOWLER™ and ZIO™); (B1.22) Pseudomonas chlororaphis, in particular strain MA342 (e.g., from Bioagri and Koppert); (B1.23) Streptomyces lydicus strain WYEC108 (also known as Streptomyces lydicus strain WYCD108US) (from Novozymes as ACTINO-IRON® and ACTINOVATE®); (B1.24) Agrobacterium radiobacter strain K84 (e.g., from AgBioChem, Canada as GALLTROL-A®); (B1.25) Agrobacterium radiobacter strain K1026 (e.g., from BASF SE as NOGALL™); (B1.26) Bacillus subtilis strain KTSB (from Donaghys as FOLIACTIVE®); (B1.27) Bacillus subtilis IAB / BS03 (from STK Bio-Ag Technologies as AVIV™); (B1.28) Bacillus subtilis strain Y1336 (available from Bion-Tech, Taiwan as BIOBAC® WP, registered as a bio-antifungal agent under Taiwan registration numbers 4764, 5454, 5096 and 5277); (B1.29) Bacillus amyloliquefaciens isolate B246 (e.g., from the University of Pretoria as AVOGREENTM); (B1.30) Bacillus methylotrophicus strain BAC-9912 (from Shenyang Institute of Applied Ecology); (B1.31) Pseudomonas proradix (e.g., from Sourcon Padena as PRORADIX®); (B1.32) Streptomyces griseobilis griseoviridis strain K61 (also known as Streptomyces galbus strain K61) (Accession No. DSM 7206) (from Verdera as MYCOSTOP®; from BioWorks as PREFENCE®; see Crop Protection 2006, 25, 468-475); (B1.33) A bacterium selected from Pseudomonas fluorescens strain A506 (e.g., from NuFarm as BLIGHTBAN® A506); and (B2) (B2.01) Coniothyrium minitans, in particular the strain CON / M / 91-8 (Accession No. DSM-9660; e.g. from Bayer CropScience Biologics GmbH as Contans®); (B2.02) Metschnikowia fructicola, in particular the strain NRRL Y-30752; (B2.03) Microsphaeropsis ochracea; (B2.04) Trichoderma atroviride, in particular the strain SC1 (Accession No. CBS 122089, WO 2009 / 116106 and US Pat. No. 8,431,120 (from Bi-PA), strain 77B (from Andermatt Biocontrol as T77) or strain LU132 (e.g. from Agrimm Technologies Limited as Sentinel); (B2.05) Trichoderma harzianum strain T-22 (e.g. from Andermatt Biocontrol or Koppert as Trianum-P) or strain Cepa Simb-T5 (from Simbiose Agro); (B2.06) Gliocladium roseum (also known as Clonostachys rosea f. rosea), in particular from Adjuvants Plus as strain 321U, strain ACM941 (Efficacy of Clonostachys rosea strain ACM941 and fungicide seed treatments for controlling the root tot complex of field pea, Can Jour Plant Sci 83(3):519-524), or strain IK726 (Jensen DF, et al.Development of a biocontrol agent for plant disease control with special emphasis on the near commercial fungal antagonist Clonostachys rosea strain 'IK726'; Australas Plant Pathol. 2007;36:95-101; (B2.07) Talaromyces flavus, strain V117b; (B2.08) Trichoderma viride, in particular strain B35 (Pietr et al., 1993, Zesz. Nauk. AR w Szczecinie 161:125-137); (B2.09) Trichoderma asperellum, in particular strain SKT-1, accession no. FERM P-16510 (e.g. from Kumiai Chemical Industry as ECO-HOPE®), strain T34 (e.g. T34 (B2.10) Trichoderma atroviride, strain CNCM I-1237 (e.g. Agrauxine as Esquive® WP, from France); (B2.11) Trichoderma atroviride, strain No. V08 / 002387; (B2.12) Trichoderma atroviride, strain NMI No. V08 / 002388; (B2.13) Trichoderma atroviride, strain NMI No. V08 / 002389; (B2.14) Trichoderma atroviride, strain NMI No. V08 / 002390;(B2.15) Trichoderma atroviride, strain LC52 (e.g., from Agrimm Technologies Limited as Tenet); (B2.16) Trichoderma atroviride, strain ATCC 20476 (IMI 206040); (B2.17) Trichoderma atroviride, strain T11 (IMI352941 / CECT20498); (B2.18) Trichoderma harmatum; (B2.19) Trichoderma harzianum; (B2.20) Trichoderma harzianum rifai T39 (e.g. from Makhteshim, USA as Trichodex®); (B2.21) Trichoderma asperellum, in particular the strain kd (e.g. from Andermatt Biocontrol as T-Gro); (B2.22) Trichoderma harzianum, strain ITEM908 (e.g. from Koppert as Trianum-P); (B2.23) Trichoderma harzianum, strain TH35 (e.g. from Mycontrol as Root-Pro); (B2.24) Trichoderma virens (Gliocladium virens); virens), in particular the strain GL-21 (e.g. from Certis, USA as SoilGard); (B2.25) Trichoderma viride, strain TV1 (e.g. from Koppert as Trianum-P); (B2.26) Ampelomyces quisqualis, in particular the strain AQ10 (e.g. from IntrachemBio Italia as AQ 10®); (B2.27) Aureobasidium pullulans, in particular blastospores of the strain DSM 14940; (B2.28) Aureobasidium pullulans, in particular blastospores of the strain DSM 14941; (B2.29) Aureobasidium pullulans, in particular blastospores of the strains DSM 14940 and DSM 14941 (e.g. Botector® from bio-ferm, Switzerland); (B2.30) Cladosporium cladosporioides, strain H39, accession no. CBS 122244, US Patent Publication No. 2010 / 0291039 (Stichting Dienst Landbouwkundig Onderzoek; (B2.31) Gliocladium catenulatum (syn. Clonostachys rosea f. catenulate) strain J1446 (e.g. from Lallemand as Prestop®); (B2.32) Lecanicillium lecanii (formerly known as Verticillium lecanii) conidia of strain KV01 (e.g. from Koppert / Arysta as Vertalec®); (B2.33) Penicillium vermiculatum; (B2.34) Pichia anomala, strain WRL-076 (NRRL Y-30842), U.S. Patent No. 7,579,183; (B2.35) Trichoderma atroviride, strain SKT-1 (FERM P-16510), JP 11-253151; (B2.36) Trichoderma atroviride, strain SKT-2 (FERM P-16511), JP 11-253151; (B2.37) Trichoderma atroviride, strain SKT-3 (FERM P-17021), JP 11-253151; (B2.38) Trichoderma gamsii (formerly T. viride), strain ICC080 (IMI CC 392151 CABI, e.g. from AGROBIOSOL DE MEXICO, SA DE CV as BioDerma); (B2.39) Trichoderma harzianum, strain DB103 (available from Dagutat Biolab as T-GRO® 7456); (B2.40) Trichoderma polysporum, strain IMI206039 (available e.g. from BINAB as Binab TF WP) (B2.41) Trichoderma stromaticum, accession no. Ts3550 (e.g., from CEPLAC, Brazil as Tricovab); (B2.42) Ulocladium oudemansii strain U3, accession no. NM99 / 06216 (e.g., from Botry-Zen Ltd, New Zealand as BOTRY-ZEN® and from BioWorks, Inc. as BOTRYSTOP®); (B2.43) Verticillium albo-atrum (formerly V. dahliae), strain WCS850, accession no. WCS850, deposited at the Central Bureau for Fungi Cultures (e.g., from Tree Care, New Zealand as DUTCH TRIG®). Innovations); (B2.44) Verticillium chlamydosporium; (B2.45) Trichoderma asperellum strain ICC012 (also known as Trichoderma harzianum ICC012), accession no.A mixture of CABI CC IMI 392716 and Trichoderma gamsii (formerly T. viride) strain ICC080, accession no. IMI392151 (e.g., from Isagro USA, Inc. as BIO-TAM™ and from Agrobiosol de Mexico, SA de CV as BIODERMA®); (B2.46) Trichoderma asperelloides JM41R (accession no. NRRL B-50759) (from BASF SE as TRICHO PLUS®); (B2.47) Aspergillus flavus strain NRRL 21882 (a product known as AFLA-GUARD® from Syngenta / ChemChina); (B2.48) Chaetomium cupreum (Accession No. CABI 353812) (e.g. from AgriLife as BIOKUPRUM™); (B2.49) Saccharomyces cerevisiae, in particular the strain LASO2 (from Agro-Levures et Derives), the strain LAS117 cell wall (from Lesaffre as CEREVISANE®; from BASF SE as ROMEO®), the strains CNCM No. I-3936, CNCM No. I-3937, CNCM No. I-3938, CNCM No. I-3939 (WO 2010 / 086790) from Lesaffre et al. (B2.50) Trichoderma virens strain G-41, formerly known as Gliocladium virens (Accession No. ATCC 20906) (e.g., as ROOTSHIELD® PLUS WP and TURFSHIELD® PLUS WP from BioWorks, USA); (B2.51) Trichoderma hamatum, Accession No. ATCC 28012; (B2.52) Ampelomyces quisqualis strain AQ10, accession no. CNCM I-807 (e.g. from IntrachemBio Italia as AQ 10®); (B2.53) Phlebiopsis gigantea strain VRA1992 (from Danstar Ferment as ROTSTOP® C); (B2.54) Penicillium steckii (DSM27859; WO 2015 / 067800) from BASF SE;. (B2.55) Chaetomium globosum (available from Rivale as RIVADIOM®); (B2.56) Cryptococcus flavescens, strain 3C (NRRL Y-50378); (B2.57) Dactylaria candida; (B2.58) Dilophosphora alopecuri (available as TWIST FUNGUS®); (B2.59) Fusarium oxysporum, strain Fo47 (available from Natural Plant Protection as FUSACLEAN®); (B2.60) Pseudozyma flocculosa, strain PF-A22UL (SPORODEX® L available from Plant Products Co., Canada under the trade name '.'; (B2.61) Trichoderma gamsii (formerly '. viride'), strain ICC080 (IMI CC 392151 CABI) (available from AGROBIOSOL DE MEXICO, SA DE CV under the trade name BIODERMA®); (B2.62) Trichoderma fertile (e.g. from BASF under the product TrichoPlus); (B2.63) Muscodor roseus, in particular strain A3-5 (Accession No. NRRL 30548); (B2.64) Fungi selected from Simplicillium lanosoniveum, A biological antifungal agent selected from: (C') (C1) (C1.01) Bacillus pumilus, in particular the strain QST2808 (Accession No. NRRL No. B-30087); (C1.02) Bacillus subtilis, in particular the strain QST713 / AQ713 (described in NRRL Accession No. B-21661 and U.S. Pat. No. 6,060,051; available as SERENADE® OPTI or SERENADE® ASO from Bayer CropScience LP, USA); (C1.03) Bacillus subtilis, in particular the strain AQ30002 (Accession No. NRRL No. 13 / 330,576); (C1.04) Bacillus subtilis, in particular strain AQ30004 (and described in NRRL B-50455 and U.S. Patent Application Publication No. 13 / 330,576); (C.1.05) SinoRhizobium meliloti strain NRG-185-1 (available from Bayer CropScience as NITRAGIN® GOLD); (C.1.06) Bacillus subtilis strain BU1814, (available from BASF SE as TEQUALIS®); (C1.07) Bacillus subtilis rm303 (available from Biofilm Crop Science as RHIZOMAX®). (C1.08) Bacillus amyloliquefaciens pm414 (from Biofilm Crop Protection as LOLI-PEPTA®); (C1.09) Bacillus mycoides BT155 (NRRL No. B-50921), Bacillus mycoides EE118 (NRRL No. B-50918), (C1.10) Bacillus mycoides EE141 (NRRL No.B-50916), Bacillus mycoides BT46-3 (NRRL No. B-50922), (C1.11) Bacillus cereus family member EE128 (NRRL No. B-50917), (C1.12) Bacillus thuringiensis BT013A (NRRL No. B-50924), also known as Bacillus thuringiensis 4Q7, (C1.13) Bacillus cereus family member EE349 (NRRL No. B-50928), (C1.14) Bacillus amyloliquefaciens amyloliquefaciens SB3281 (ATCC# PTA-7542; WO 2017 / 205258), (C1.15) Bacillus amyloliquefaciens TJ1000 (available from Novozymes as QUIKROOTS®); (C1.16) Bacillus firmus, in particular the strain CNMC I-1582 (e.g. from BASF SE as VOTIVO®); (C1.17) Bacillus pumilus, in particular the strain GB34 (e.g. from Bayer Crop Science, Germany as YIELD SHIELD®); (C1.18) Bacillus amyloliquefaciens amyloliquefaciens, in particular the strain IN937a; (C1.19) Bacillus amyloliquefaciens, in particular the strain FZB42 (e.g. RHIZOVITAL® from ABiTEP, Germany); (C1.20) Bacillus amyloliquefaciens BS27 (Accession No. NRRL B-5015); (C1.21) a mixture of Bacillus licheniformis FMCH001 and Bacillus subtilis FMCH002 (available from FMC Corporation as QUARTZO® (WG), PRESENCE® (WP); (C1.22) Bacillus cereus, in particular the strain BP01 (ATCC 55675; e.g. from Arysta Lifescience, USA as MEPICHLOR®); (C1.23) Bacillus subtilis, in particular the strain MBI600 (e.g. from BASF SE as SUBTILEX®); (C1.24) Bradyrhizobium japonicum japonicum) (e.g. from Novozymes as OPTIMIZE®); (C1.25) Mesorhizobium cicer (e.g. from BASF SE as NODULATOR); (C1.26) Rhizobium leguminosarium biovar viciae (e.g. from BASF SE as NODULATOR); (C1.27) Delftia acidovorans, in particular the strain RAY209 (e.g. from Brett Young Seeds as BIOBOOST®); (C1.28) Lactobacillus sp. (e.g. from LactoPAFI as LACTOPLANT®); Paenibacillus polymyxa, in particular strain AC-1 (e.g., from Green Biotech Company Ltd. as TOPSEED®); (C1.29) Pseudomonas proradix (e.g., from Sourcon Padena as PRORADIX®); (C1.30) Azospirillum brasilense (e.g., from KALO, Inc. as VIGOR®).(C1.31) Azospirillum lipoferum (e.g., from TerraMax, Inc. as VERTEX-IFTM); (C1.32) a mixture of Azotobacter vinelandii and Clostridium pasteurianum (available from Agrinos as INVIGORATE®); (C1.33) Pseudomonas aeruginosa, in particular the strain PN1; (C1.34) Rhizobium leguminosarum, in particular the physiological type viceae strain Z25 (Accession No. CECT 4585); (C1.35) Azorhizobium carinodans caulinodans, in particular the strain ZB-SK-5; (C1.36) Azotobacter chroococcum, in particular the strain H23; (C1.37) Azotobacter vinelandii, in particular the strain ATCC12837; (C1.38) Bacillus siamensis, in particular the strain KCTC13613T; (C1.39) Bacillus tequilensis, in particular the strain NII-0943; (C1.40) Serratia marcescens, in particular the strain SRM (Accession No. MTCC 8708); (C1.41) Thiobacillus sp.) (e.g., from Cropaid Ltd UK as CROPAID®); and (C2) (C2.01) Purpureocillium lilacinum (formerly known as Paecilomyces lilacinus) strain 251 (AGAL 89 / 030550; e.g. from Bayer CropScience Biologics GmbH as BioAct); (C2.02) Penicillium bilaii, strain ATCC22348 (e.g. from Acceleron BioAg as JumpStart®), (C2.03) Talaromyces flavus strain V117b; (C2.04) Trichoderma atroviride strain CNCM I-1237 (e.g. from Agrauxine, France as Esquive® WP); (C2.05) Trichoderma viride, e.g. strain B35 (Pietr et al., 1993, Zesz. Nauk. AR w Szczecinie 161: 125-137); (C2.06) Trichoderma atroviride strain LC52 (also known as Trichoderma atroviride strain LU132; e.g. from Agrimm Technologies Limited as Sentinel); (C2.07) Trichoderma atroviride strain SC1, described in WO 2008 / 000196); (C2.08) Trichoderma aspereum asperellum strain kd (e.g., from Andermatt Biocontrol as T-Gro); (C2.09) Trichoderma asperellum strain Eco-T (Plant Health Products, South Africa); (C2.10) Trichoderma harzianum strain T-22 (e.g. from Andermatt Biocontrol or Koppert as Trianum-P); (C2.11) Myrothecium verrucaria strain AARC-0255 (e.g. from Valent Biosciences as DiTera®); (C2.12) Penicillium bilaii strain ATCC ATCC20851; (C2.13) Pythium oligandrum strain M1 (ATCC 38472; e.g. from Bioprepraty, Czech Republic as Polyversum); (C2.14) Trichoderma virens virens strain GL-21 (e.g. from Certis, USA as SoilGard®); (C2.15) Verticillium albo-atrum (formerly V. dahliae) strain WCS850 (CBS 276.92; e.g. from Tree Care Innovations as Dutch Trig); (C2.16) Trichoderma atroviride, in particular strain No. V08 / 002387, strain No. NMI No. V08 / 002388, strain No. NMI No. V08 / 002389, strain No. NMI No. V08 / 002390; (C2.17) Trichoderma harzianum harzianum, strain ITEM908; (C2.18) Trichoderma harzianum, strain TSTh20; (C2.19) Trichoderma harzianum, strain 1295-22; (C2.20) Pythium oligandrum, strain DV74; (C2.21) Rhizopogon amylopogon (e.g., contained in Myco-Sol from Helena Chemical Company); (C2.22) Rhizopogon fulvigleba (e.g., contained in Myco-Sol from Helena Chemical Company); and (C2.23) Trichoderma virens strain GI-3. A biological control agent having an effect of improving plant growth and / or plant health selected from (D) (D1) (D1.01) Bacillus thuringiensis subsp. aizawai, in particular strain ABTS-1857 (SD-1372; e.g., from Valent BioSciences as XENTARI®; (D1.02) Bacillus mycoides isolate J. (e.g., from Certis USA LLC, a Mitsui & Co. subsidiary as BmJ); (D1.03) Bacillus sphaericus, in particular serotype H5a5b strain 2362 (strain ABTS-1743) (e.g., from Valent BioSciences, USA as VECTOLEX®); (D1.04) Bacillus thuringiensis subsp. kurstaki strain BMP123 from Becker Microbial Products, Israel; (D1.05) Bacillus thuringiensis subsp. aizawai, in particular serotype H-7 (e.g., from Valent BioSciences, USA, as FLORBAC® WG); (D1.06) Bacillus thuringiensis subsp. kurstaki strain HD-1 (e.g., from Valent BioSciences, USA, as DIPEL® ES); (D1.07) Bacillus thuringiensis subsp. kurstaki strain BMP123 from Becker Microbial Products, Israel; (D1.08) Bacillus thuringiensis israelensis strain BMP144 (e.g., from Becker Microbial Products Israel as AQUABAC®); (D1.09) Burkholderia spp.), in particular Burkholderia rinojensis strain A396 (also known as Burkholderia rinojensis strain MBI305) (Accession No. NRRL B-50319; WO 2011 / 106491 and WO 2013 / 032693; e.g. from Marrone Bio Innovations as MBI-206 TGAI and ZELTO®); (D1.10) Chromobacterium subtsugae, in particular strain PRAA4-1T (MBI-203; e.g. from Marrone Bio Innovations as GRANDEVO®); (D1.11) Paenibacillus popiliae popilliae) (formerly Bacillus popilliae); e.g., from St. Gabriel Laboratories as MILKY SPORE POWDER™ and MILKY SPORE GRANULARTM; (D1.12) Bacillus thuringiensis subsp. israelensis (serotype H-14) strain AM65-52 (Accession No. ATCC 1276) (e.g., from Valent BioSciences, USA as VECTOBAC®); (D1.13) Bacillus thuringiensis var. kurstaki strain EVB-113-19 (e.g., from AEF Global as BIOPROTEC®); (D1.14) Bacillus thuringiensis subsp. tenebrionis (D1.15) Bacillus thuringiensis var. japonensis strain Buibui; (D1.16) Bacillus thuringiensis subsp. kurstaki strain ABTS351; (D1.17) Bacillus thuringiensis subsp. kurstaki strain PB54; (D1.18) Bacillus thuringiensis subsp. kurstaki strain SA11; (D1.19) Bacillus thuringiensis subsp. kurstaki strain SA12; (D1.20) Bacillus thuringiensis subsp. kurstaki strain EG2348; (D1.21) Bacillus thuringiensis var. Colmeri (e.g., from Changzhou Jianghai Chemical Factory as TIANBAOBTC); (D1.22) Bacillus thuringiensis subsp. aizawai strain GC-91; (D1.23) Serratia entomophila (e.g., from Wrightson Seeds as INVADE®); (D1.24) Serratia marcescens, in particular strain SRM (Accession No. MTCC 8708); and (D1.25) Wolbachia pipientis strain ZAP (e.g., from MosquitoMate as ZAP MALES®); and (D2) (D2.01) Isaria fumosorosea (formerly known as Paecilomyces fumosoroseus) strain apopka97; (D2.02) Beauveria bassiana strain ATCC 74040 (e.g., from Intrachem Bio Italia as NATURALIS®); (D2.03) Beauveria bassiana strain GHA (Accession No. ATCC 74250; e.g., from Laverlam International Corporation as BOTANIGUARD® ES and MYCONTROL-O®); (D2.04) Zoophtora radicans; (D2.05) Metarhizium robertii (D2.06) Metarhizium robertsii 15013-1 (deposited under NRRL Accession No. 67073), (D2.07) Metarhizium anisopliae 3213-1 (deposited under NRRL Accession No. 67074) (WO 2017 / 066094; Pioneer Hi-Bred International); (D2.08) Beauveria bassiana strain ATP02 (Accession No. DSM24665), an insecticidally active biological control agent selected from (E) a virus selected from the group consisting of Adoxophyes orana (small apple tortrix) granulosis virus (GV), Cydia pomonella (codling moth) granulosis virus (GV), Helicoverpa armigera (cotton budworm larvae) nuclear polyhedrosis virus (NPV), Spodoptera exigua (beet armyworm larvae) mNPV, Spodoptera frugiperda (stalk fall armyworm) mNPV, and Spodoptera littoralis (African cotton leafworm) NPV; (F) Agrobacterium spp., Azorhizobium caulinodans, Azospirillum spp., Azotobacter spp., Bradyrhizobium spp., Burkholderia spp., in particular Burkholderia cepacia (formerly known as Pseudomonas cepacia), Gigaspora spp., or Gigaspora monosporum, Glomus spp., Laccaria spp., Bacteria and fungi that can be added as "seed" to plants or plant parts or plant organs and that improve plant growth and plant health thanks to their specific properties, selected from the genera Lactobacillus buchneri, Paraglomus spp., Pisolithus tinctorus, Pseudomonas spp., Rhizobium spp., in particular Rhizobium trifolii, Rhizopogon spp., Scleroderma spp., Suillus spp. and Streptomyces spp.; and (G) Allium sativum, Artemisia absinthium, Azadirachtin, Biokeeper WP, Cassia nigricans, Celastrus angulatus, Chenopodium anthelminticum, Chitin, Armour-Zen, Dryopteris filix-mas, Equisetum arvense, Fortune Aza, Fungastop, Heads Up (Chenopodium quinoa Saponin Extract), Pyrethrum / Pyrethrins, Cassia amara amara, Quercus, Quillaja, Regalia, 'Requiem® insecticide', rotenone, ryania / ryanodine, Symphytum officinale, Tanacetum vulgare, thymol, Triact 70, TriCon, Tropaeulum majus, Urtica dioica, veratrine, Viscum album, Brassicaceae extracts, in particular rapeseed powder or mustard powder, as well as olive oil, in particular those with carbon chain length C, as active ingredients, for example as contained in products under the trade name FLiPPER®. 16 ~C 20 Plant extracts and products produced by microorganisms containing proteins and secondary metabolites that can be used as biological control agents selected from bioinsecticidal / acaricidal active substances obtained from unsaturated fatty acids / carboxylic acids having A biological control agent selected from and a further active compound selected from The present invention provides an active compound combination comprising: DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0006] As used herein, the term "biological control" is defined as the control of pests such as phytopathogenic fungi and / or insects and / or mites and / or nematodes by the use or action of biological control agents.

[0007] As used herein, the term "biological control agent" is defined as an organism other than a pest and / or a protein or secondary metabolite produced by such an organism for the purpose of biological control. Mutants of a second organism should be included within the definition of a biological control agent. The term "mutant" refers to variants of a parent strain as well as methods of obtaining mutants or variants whose pesticidal activity is greater than that expressed by the parent strain. "Parent strain" is defined herein as the original strain prior to mutagenesis. To obtain such mutants, the parent strain may be treated with chemicals such as N-methyl-N'-nitrosoguanidine, ethyl methanesulfone, or by irradiation with gamma, x-ray, or UV radiation, or by other means known to those skilled in the art. A known mechanism of biological control agents comprises enterobacteria that control root rot caused by fungi that outcompete for space on the root surface. Bacterial toxins such as antibiotics have been used to control pathogenic bacteria. The toxin can be isolated and sprayed directly on the plant, or a bacterial species may be administered, which produces the toxin in situ.

[0008] A "variant" is a strain that has all of the identifying characteristics of the NRRL or ATCC accession number set forth in the text and can be identified as having a genome that hybridizes to the genome of the NRRL or ATCC accession number under highly stringent conditions.

[0009] "Hybridization" refers to a reaction in which one or more polynucleotides react to produce a complex stabilized by hydrogen bonds between the bases of the nucleotide residues. Hydrogen bonds may occur by Watson-Crick base pairing, Hoogstein binding, or in other sequence-specific manner. The complex may comprise two strands forming a double-stranded structure, three or more strands forming a multi-stranded complex, single-stranded self-hybridizing strands, or any combination of these. Hybridization reactions can be performed under conditions of different "stringency." In general, low stringency hybridization reactions are performed at about 40°C in 10X SSC or in solutions of equivalent ionic strength / temperature. Moderate stringency hybridizations are typically performed at about 50°C in 6X SSC, and high stringency hybridization reactions are typically performed at about 60°C in 1X SSC.

[0010] A variant of the indicated NRRL or ATCC accession number may be further defined as a strain having a genome sequence that is more than 85%, more preferably more than 90% or more preferably more than 95% sequence identity to the genome of the indicated NRRL or ATCC accession number. A polynucleotide or polynucleotide region (or a polypeptide or polypeptide region), when aligned, has a certain percentage (e.g., 80%, 85%, 90%, or 95%) of "sequence identity" to another sequence means that the percentage of bases (or amino acids) are the same in a comparison of the two sequences. The sequence and percent homology or percent sequence identity can be determined using software programs known in the art, such as those described in Current Protocols in Molecular Biology (FM Ausubel et al., eds., 1987).

[0011] NRRL is an abbreviation for Agricultural Research Service Culture Collection, an international depository for the purpose of depositing microbial strains under the Budapest Treaty on the International Recognition of the Deposit of Microorganisms for the Purposes of Patent Procedure, National Center for Agricultural Utilization Research, Agricultural Research service, USDA department of Agriculture, 1815 North university Street, Peroira, Illinois 61604 USA.

[0012] ATCC is the abbreviation for American Type Culture Collection, an international depository for the purposes of depositing microbial strains under the Budapest Treaty on the International Recognition of the Deposit of Microorganisms for the Purposes of Patent Procedure, ATCC Patent Depository, 10801 University Blvd., Manassas, VA 10110 USA.

[0013] The active compound combination according to the invention comprises as compound (A) methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid or mixtures thereof, which may be present in the form of their salts or N-oxides, which also have antifungal properties.

[0014] Methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate is represented by the formula (I-1):

[0015] [ka]

[0016] The compound is also referred to as (I-1) or simply (I-1) as follows. 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid is represented by the formula (I-2):

[0017] [ka]

[0018] The compound is also referred to as (I-2) or simply (I-2) as follows:

[0019] As is evident from formulae (I-1) and (I-2), compounds (I-1) and (I-2) comprise a stereocenter at the carbon atom bearing the hydroxy group. The compounds can therefore exist in the form of optical isomers, their racemic or scalemic mixtures in all proportions (the term "scalemic" denotes a mixture of enantiomers in different proportions).The compounds (I-1) and (I-2) may be used in the active compound combination according to the invention in any of the abovementioned forms, i.e. (I-1) is methyl (2R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, methyl (2S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, methyl (2R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3- Racemic mixtures of methyl (1,2,4-triazol-1-yl)propanoate and methyl (2S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate, and racemic mixtures of methyl (2R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate and methyl (2S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate and (I-2) may exist as a scalemic mixture of either (2R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid, (2S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid, (2R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid, It may exist as a racemic mixture of either (2R)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid and (2S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoic acid.

[0020] Preferably, the active compound combination according to the invention comprises compound (I-1) as compound (A).

[0021] The active compound combination according to the invention comprises an active ingredient selected from the compounds indicated above as compound (B).

[0022] The compound (B) is preferably - inhibitors of ergosterol synthesis selected from: (1.009) fluoxythioconazole and (1.014) imazalil sulfate, - (2.005) inhibitors of the respiratory chain in complex I or II selected from cyclobutrifluram, (2.006) fulveneteram, - inhibitors of the respiratory chain in complex III selected from: (3.005) cumoxystrobin, (3.017) methallylpicoxamide, (3.023) pyrametostrobin, - compounds capable of having a multi-site action selected from the group consisting of: (5.001) Bordeaux mixture, (5.005) copper hydroxide, (5.006) copper naphthenate, (5.007) copper oxide, (5.008) copper oxychloride, (5.009) copper(2+) sulfate, (5.016) zinc metiram, (5.017) copper oxine, (5.019) sulfur preparations containing calcium polysulfide, - compounds capable of inducing host defense selected from (6.003) fosetyl calcium, (6.004) fosetyl sodium, (6.008) tiadinil, - (7.003) inhibitors of amino acid and / or protein biosynthesis selected from kasugamycin hydrochloride hydrate, - inhibitors of lipid synthesis or transport, or membrane synthesis, selected from (10.005) propamocarb hydrochloride and (10.006) propamocarb fosetylate, -(15.001) abscisic acid, (15.003) benthazole, (15.004) bethoxazin, (15.005) capsimycin, (15.006) carvone, (15.008) chlorinconazide, (15.009) khuraneb, (15.012) cyprosulfamide, (15.015) flufenoxadiazam, (15.016) flumethylsulfolim, (15.018) methyl isothiocyanate, (15.019) mildiomycin, (15.020) nickel dimethyldithiocarbamate, (15.021) Nitrothalisopropyl, (15.022) Oxyfenthiin, (15.023) Pentachlorophenol and salts, (15.026) D-tagatose, (15.029) Tornifanide, (15.045) 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.046) 1-(5-(fluoromethyl)-6-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15. 047) 1-(5,6-dimethylpyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.048) 1-(6-(difluoromethyl)-5-methoxy-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.049) 1-(6-(difluoromethyl)-5-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.050) 1-(6,7-dimethylpyrazolo[1, 5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.051) 2-{2-fluoro-6-[(8-fluoro-2-methylquinolin-3-yl)oxy]phenyl}propan-2-ol, (15.052) 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.053) 3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-8-fluoroquinoline, (15.054) 3-(4,4-difluoro-5,5-dimethyl-4,5-dihydrothieno[2,3-c]pyridin-7-yl)quinoline, (15.055) 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.056) 5-bromo-1-(5,6-dimethylpyridin-3-yl)-3,3-dimethyl-3,4-dihydroisoquinoline, (15.057) 8-fluoro-3-(5-fluoro-3,3,4,4-tetramethyl-3,4 -dihydroisoquinolin-1-yl)-quinoline, (15.058) 8-fluoro-3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-quinoline, (15.059) 8-fluoro-N-(4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl)quinoline-3-carboxamide, (15.060) 8-fluoro-N-[(2S)-4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl]quinoline-3-carboxamide , (15.061) 9-fluoro-2,2-dimethyl-5-(quinolin-3-yl)-2,3-dihydro-1,4-benzoxazepine, (15.062) N-(2,4-dimethyl-1-phenylpentan-2-yl)-8-fluoroquinoline-3-carboxamide, (15.063) N-[(2S)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063A) N-[(2R)-2,4-dimethyl-1-phenylpentan- 2-yl]-8-fluoroquinoline-3-carboxamide, (15.063B) 2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.063C) (2S)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide and (15.063D) (2R)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide. - (A1.01) Bacillus subtilis, strain QST713 / AQ713 (available as SERENADE OPTI or SERENADE ASO from Bayer CropScience LP, USA, NRRL Accession No. B21661, U.S. Patent No. 6,060,051), (A1.06) Bacillus subtilis strain BU1814 (available as VELONDIS® PLUS, VELONDIS® FLEX and VELONDIS® EXTRA from BASF SE), (B1.02) Bacillus pumilus strain QST2808 (available as SONATA® from Bayer CropScience LP, USA, NRRL Accession No. No. 6,245,551; (B1.03) Bacillus pumilus, strain GB34 (available from Bayer AG, Germany as Yield Shield®); (B1.04) Bacillus pumilus, strain BU F-33, NRRL Accession No. 50185 (available from BASF as part of the CARTISSA products, EPA Registration No. 71840-19); (B1.07) Bacillus subtilis strain MBI600 (available from BASF SE as SUBTILEX), Accession No. NRRL B-50595; U.S. Pat. No. 5,061,495; (B1.08) Bacillus subtilis, strain BU F-33, NRRL Accession No. 50185 (available from BASF SE as SUBTILEX), EPA Registration No. 71840-19; subtilis strain GB03 (available as Kodiak® from Bayer AG, Germany), (B1.19) Paenibacillus polymyxa ssp. Plantarum (WO 2016 / 020371) from BASF SE, (B1.20) Paenibacillus epiphyticus (WO 2016 / 020371) from BASF SE (B1.25) Agrobacterium radiobacter strain K1026 (e.g. from BASF SE as NOGALL™), (B2.01) Coniothyrium minitans, strain CON / M / 91-8 (Accession No. DSM 9660; e.g. from Bayer CropScience Biologics GmbH as Contans®), (B2.54) Penicillium steckii (DSM 27859; WO 2015 / 067800) from BASF SE, (B2.62) Trichoderma fertile (e.g. from BASF as the product TrichoPlus), (C.1.05) SinoRhizobium meliloti strain NRG-185-1 (available from Bayer CropScience as NITRAGIN® GOLD), (C.1.06) Bacillus subtilis strain BU1814 (available from BASF SE as TEQUALIS®), (C1.16) Bacillus firmus, strain CNMC I-1582 (e.g. from BASF SE as VOTIVO®), (C1.17) Bacillus pumilus, strain GB34 (e.g. from Bayer Crop Science, Germany as YIELD SHIELD®), (C1.23) Bacillus subtilis, strain MBI600 (e.g. from BASF SE as SUBTILEX®). SE), (C1.25) MesoRhizobium cicer (e.g., from BASF SE as NODULATOR), (C1.26) Rhizobium leguminosarium biovar viciae (e.g. from BASF SE as NODULATOR) as well as (G1) unsaturated fatty acids / carboxylic acids obtained from olive oil with carbon chain length C16-C20 as active ingredients available as products under the trade name FLiPPER®. A biological control agent selected from is selected from.

[0023] The compound (B) is more preferably - inhibitors of ergosterol synthesis selected from: (1.009) fluoxythioconazole and (1.014) imazalil sulfate, - (2.005) inhibitors of the respiratory chain in complex I or II selected from cyclobutrifluram, (2.006) fulveneteram, - inhibitors of the respiratory chain in complex III selected from: (3.005) cumoxystrobin, (3.017) methallylpicoxamide, (3.023) pyrametostrobin, - compounds capable of having a multi-site action selected from the group consisting of: (5.001) Bordeaux mixture, (5.005) copper hydroxide, (5.006) copper naphthenate, (5.007) copper oxide, (5.008) copper oxychloride, (5.009) copper(2+) sulfate, (5.016) zinc metiram, (5.017) copper oxine, (5.019) sulfur preparations containing calcium polysulfide, - compounds capable of inducing host defense selected from (6.003) fosetyl calcium, (6.004) fosetyl sodium, (6.008) tiadinil, - (7.003) inhibitors of amino acid and / or protein biosynthesis selected from kasugamycin hydrochloride hydrate, (10.005) Inhibitors of lipid synthesis or transport, or membrane synthesis, selected from propamocarb hydrochloride and (10.006) propamocarb fosetylate, and -(15.001) Abscisic acid, (15.003) Benthazole, (15.004) Bethoxazin, (15.005) Capsimycin, (15.006) Carvone, (15.008) Chlorinconazide, (15.009) Kufuraneb, (15.012) Cyprosulfamide, (15.015) Flufenoxadiazam, (15.016) Flumethylsulfolim, (15.018) Methyl isothiocyanate, (15.019) Mildiomycin, (15.020) Nickel dimethyldithiocarbamate, (15.021) Nitrothalisopropyl (15.022) Oxyfenthiin, (15.023) Pentachlorophenol and salts, (15.026) D-tagatose, (15.029) Tornifanide, (15.045) 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.050) 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.059) 8-fluoro-N-(4,4,4 -trifluoro-2-methyl-1-phenylbutan-2-yl)quinoline-3-carboxamide, (15.060) 8-fluoro-N-[(2S)-4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl]quinoline-3-carboxamide, (15.062) N-(2,4-dimethyl-1-phenylpentan-2-yl)-8-fluoroquinoline-3-carboxamide, (15.063) N-[(2S)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063A) N - [(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063B) 2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.063C) (2S)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide and (15.063D) (2R)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, is selected from.

[0024] Compound (B) is even more preferably (1.009) fluoxythioconazole, (2.005) cyclobutrifluram, (3.017) methallyl picoxamide, (15.015) Flufenoxadiazam, (15.016) Flumethylsulfolim, (15.045) 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.050) 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.06 0) 8-Fluoro-N-[(2S)-4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl]quinoline-3-carboxamide, (15.063A) N-[(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide and (15.063D) (2R)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide is selected from. Compound (B) is most preferably (3.017) methallyl picoxamide.

[0025] The active compound combination according to the present invention may, if necessary, comprise as compound (C) the following compounds (1') to (15'): (1') (1.001) cyproconazole, (1.002) difenoconazole, (1.003) epoxiconazole, (1.004) fenbuconazole, (1.005) fenhexamid, (1.006) fenpropidin, (1.007) fenpropimorph, (1.008) fenpyrazamine, (1.009) fluoxythioconazole, (1.010) fluquinconazole, (1.011) flutriafol, (1.012) hexaconazole, (1.013) imazalil, (1.014) imazalil sulfate, (1 .015) Ipconazole, (1.016) Ipfentrifluconazole, (1.017) Mefentrifluconazole, (1.018) Metconazole, (1.019) Myclobutanil, (1.020) Paclobutrazol, (1.021) Penconazole, (1.022) Prochloraz, (1.023) Propiconazole, (1.024) Prothioconazole, (1.025) Pyrizoxazole, (1.026) Spiroxamine, (1.027) Tebuconazole, (1.028) Tetraconazole, (1.029) Triconazole Azimenol, (1.030) Tridemorph, (1.031) Triticonazole, (1.032) (1R,2S,5S)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.033) (1S,2R,5R)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.034) (2R)-2-(1-chlorocyclopropyl)cyclopentanol )-4-[(1R)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.035)(2R)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.036)(2R)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol, (1.037) (2S)-2-(1-chlorocyclopropyl)-4-[(1R)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.038) (2S)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.039) (2S)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl )phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol, (1.040)(R)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.041)(S)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.042 ) [3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.043) 1-({(2R,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole, (1.044) 1-({(2S,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4- Methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole, (1.045) 1-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl thiocyanate, (1.046) 1-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl thiocyanate, (1.047) 1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl thiocyanate, (1.048) 2-[(2R,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.049) 2-[(2R,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.050) 2-[(2R,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione 1.051) 2-[(2R,4S,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.052) 2-[(2S,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione Triazole-3-thione, (1.053) 2-[(2S,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.054) 2-[(2S,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.055) 2-[(2S,4S,5S)-1-(2,4-di 2-[1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.056) 2-[1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.057) 2-[6-(4-bromophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol, (1.058) 2-[6-(4-chlorophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol, (1.059) 2-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.060) 2-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.061) 2-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.062) 3-[2-(1-chlorocyclopropyl)-3-(3-chloro-2-fluoro-phenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile, (1.063) 5-(4-chlorobenzyl)- 2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.064) 5-(arylsulfanyl)-1-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole, (1.065) 5-(arylsulfanyl)-1-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2, 4-Triazole, (1.066) 5-(arylsulfanyl)-1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole, (1.068) N'-(2-chloro-5-methyl-4-phenoxyphenyl)-N-ethyl-N-methylimidoformamide, (1.069) N'-[2-chloro-4-(2-fluorophenoxy)-5-methylphenyl]-N-ethyl-N-methylimidoformamide, (1.070) N'-[5-bromo-6-(2,3-dihydro-1H-inden-2-yloxy)-2-methylpyridin-3-yl]-N-ethyl-N-methylimidoformamide, (1.071) N'-{4-[(4,5-dichloro-1,3-thiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylimidoformamide, (1.072) N'-{5-bromo-2-methyl-6-[(1-propoxy propan-2-yl)oxy]pyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.073) N'-{5-bromo-6-[(1R)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.074) N'-{5-bromo-6-[(1S)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.075) N'-{5-bromo-6-[(cis-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.076) N'-{5-bromo-6-[(trans-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1 .077) an inhibitor of ergosterol synthesis selected from the group consisting of N'-{5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.078) N-isopropyl-N'-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-phenylethyl)phenyl]-N-methylimidoformamide. (2') (2.001) benzovindiflupyr, (2.002) bixafen, (2.003) boscalid, (2.004) carboxin, (2.005) cyclobutrifluram, (2.006) fluveneteram, (2.007) fluindapyr, (2.008) fluopyram, (2.009) flutolanil, (2.010) fluxapyroxad, (2.011) furametpyr, (2.012) impilfluxam, (2.013) isofetamide, (2.014) isoflucipram, (2.015) isopyrazam, (2.016) penflufe , (2.017) penthiopyrad, (2.018) pydiflumetofen, (2.019) pyrapropoin, (2.020) pyraziflumide, (2.021) sedaxane, (2.022) thifluzamide, (2.023) 1,3-dimethyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide, (2.024) 1,3-dimethyl-N-[(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2. 025) 1,3-dimethyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2.026) 1-methyl-3-(trifluoromethyl)-N-[2'-(trifluoromethyl)biphenyl-2-yl]-1H-pyrazole-4-carboxamide, (2.027) 2-fluoro-6-(trifluoromethyl)-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)benzamide, (2.028) 3-(difluoromethyl)-1-methyl (2.029) 3-(difluoromethyl)-1-methyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2.030) 3-(difluoromethyl)-N-[(3R)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.040) 3-(difluoromethyl)-N-[(3R)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.050) 3-(difluoromethyl)-N-[(3R)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.060)031) 3-(difluoromethyl)-N-[(3S)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.032) 5,8-difluoro-N-[2-(2-fluoro-4-{[4-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)ethyl]quinazolin-4-amine, (2.033) N-[(1R,4S)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.0 34) Inhibitors of the respiratory chain in complex I or II selected from the group consisting of N-[(1S,4R)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.035) N-[1-(2,4-dichlorophenyl)-1-methoxypropan-2-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.036) N-[rac-(1S,2S)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)nicotinamide. (3') (3.001) amethoctrazine, (3.002) amisulbrom, (3.003) azoxystrobin, (3.004) methoxystrobin, (3.005) cumoxystrobin, (3.006) cyazofamid, (3.007) cymoxystrobin, (3.008) enoxastrobin, (3.009) famoxadone, (3.010) fenamidone, (3.011) fenpicoxamide, (3.012) flurylpicoxamide, (3.013) flufenoxystrobin, (3.014) ) fluoxastrobin, (3.015) kresoxim-methyl, (3.016) mandestrobin, (3.017) methallylpicoxamide, (3.018) metominostrobin, (3.019) methyltetraprole, (3.020) orysastrobin, (3.021) picoxystrobin, (3.022) pyraclostrobin, (3.023) pyrametostrobin, (3.024) pyraoxystrobin, (3.025) trifloxystrobin, (3.026) (2E)-2-{2-[({[(1E )-1-(3-{[(E)-1-fluoro-2-phenylvinyl]oxy}phenyl)ethylidene]amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide, (3.027) (2E,3Z)-5-{[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.028) (2R)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide Inhibitors of the respiratory chain in complex III selected from the group consisting of: (2S)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide, (3.029) (2S)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide, (3.030) N-(3-ethyl-3,5,5-trimethylcyclohexyl)-3-formamido-2-hydroxybenzamide, (3.031) (2E,3Z)-5-{[1-(4-chloro-2-fluorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.032) methyl {5-[3-(2,4-dimethylphenyl)-1H-pyrazol-1-yl]-2-methylbenzyl}carbamate,(4') (4.001) carbendazim, (4.002) diethofencarb, (4.003) ethaboxam, (4.004) fluopicolide, (4.005) fluopimomide, (4.006) metrafenone, (4.007) pencycuron, (4.008) pyridaclomethyl, (4.009) pyriophenone (clazafenone), (4.010) thiabendazole, (4.011) thiophanate-methyl, (4.012) zoxamide, (4.013) 3-chloro-5-(4-chlorophenyl)-4-(2,6-difluoro phenyl)-6-methylpyridazine, (4.014) 3-chloro-5-(6-chloropyridin-3-yl)-6-methyl-4-(2,4,6-trifluorophenyl)pyridazine, (4.015) 4-(2-bromo-4-fluorophenyl)-N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.016) 4-(2-bromo-4-fluorophenyl)-N-(2-bromo-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.017) 4-(2- bromo-4-fluorophenyl)-N-(2-bromophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.018) 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.019) 4-(2-bromo-4-fluorophenyl)-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.020) 4-(2-bromo-4-fluorophenyl)-N-(2-fluorophenyl)- 1,3-dimethyl-1H-pyrazol-5-amine, (4.021) 4-(2-chloro-4-fluorophenyl)-N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.022) 4-(2-chloro-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.023) 4-(2-chloro-4-fluorophenyl)-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.024) 4-(2-chloro-4-fluorophenyl)-N-(2-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.025) 4-(4-chlorophenyl)-5-(2,6-difluorophenyl)-3,6-dimethylpyridazine, (4.026) N-(2-bromo-6-fluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.027) N-(2-bromophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.028) N-(4-chloro-2,6-difluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, inhibitors of mitosis and cell division selected from the group consisting of: (5') (5.001) Bordeaux mixture, (5.002) captafol, (5.003) captan, (5.004) chlorothalonil, (5.005) copper hydroxide, (5.006) copper naphthenate, (5.007) copper oxide, (5.008) copper oxychloride, (5.009) copper(II) sulfate, (5.010) dithianon, (5.011) dodine, (5.012) folpet, (5.013) mancozeb, (5.014) maneb, (5.015) metiram, (5.0 16) Compounds capable of having a multi-site action selected from the group consisting of metiram zinc, (5.017) oxine copper, (5.018) propineb, (5.019) sulfur preparations containing sulfur and calcium polysulfide, (5.020) thiram, (5.021) zineb, (5.022) ziram, (5.023) 6-ethyl-5,7-dioxo-6,7-dihydro-5H-pyrrolo[3',4':5,6][1,4]dithiino[2,3-c][1,2]thiazole-3-carbonitrile; (6') Compounds which may induce host defense selected from the group consisting of (6.001) acibenzolar-S-methyl, (6.002) fosetyl aluminum, (6.003) fosetyl calcium, (6.004) fosetyl sodium, (6.005) isotianil, (6.006) phosphorous acid and its salts, (6.007) probenazole, (6.008) tiadinil; (7') inhibitors of amino acid and / or protein biosynthesis selected from the group consisting of (7.001) cyprodinil, (7.002) kasugamycin, (7.003) kasugamycin hydrochloride hydrate, (7.004) oxytetracycline, (7.005) pyrimethanil, (8') (8.001) the inhibitor of ATP production selected from the group consisting of silthiofam, (9') inhibitors of cell wall synthesis selected from the group consisting of (9.001) benthiavalicarb, (9.002) dimethomorph, (9.003) flumorph, (9.004) iprovalicarb, (9.005) mandipropamide, (9.006) pyrimorph, (9.007) valifenalate, (9.008) (2E)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-1-(morpholin-4-yl)prop-2-en-1-one, (9.009) (2Z)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-1-(morpholin-4-yl)prop-2-en-1-one, (10') (10.001) Fluoxapiproline, (10.002) Natamycin, (10.003) Oxathiapiproline, (10.004) Propamocarb, (10.005) Propamocarb hydrochloride, (10.006) Propamocarb fosetylate, (10.007) Tolclofos-methyl, (10.008) 1-(4-{4-[(5R)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluorophenyl)phenyl]piperidin-1-yl] (10.009) 1-(4-{4-[(5S)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone, (10.010) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-(prop-2-yn-1-yloxy)phenyl]- 4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.011) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-chloro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.012) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl ]-1-[4-(4-{5-[2-fluoro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.013) 2-{(5R)-3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate, (10.014) 2-{(5S)-3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate, (10.015) 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidine- 4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}phenyl methanesulfonate, (10.016) 3-[2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (10.017) 9-fluoro-2,4-benzodioxepin-6-yl methanesulfonate, Fluoro-3-[2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (10.018) 3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol- 4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (10.019) 3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-9-fluoro-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (11') (11.001) tolprocarb, (11.002) tricyclazole, (12') inhibitors of nucleic acid synthesis selected from the group consisting of (12.001) benalaxyl, (12.002) benalaxyl-M (chiralaxyl), (12.003) metalaxyl, (12.004) metalaxyl-M (mefenoxam), (13') signal transduction inhibitors selected from the group consisting of (13.001) fludioxonil, (13.002) iprodione, (13.003) procymidone, (13.004) proquinazide, (13.005) quinoxyfen, (13.006) vinclozolin, (14') (14.001) fluazinam, (14.002) meptyldinocap, a compound capable of acting as an uncoupler selected from the group consisting of (15') (15.001) abscisic acid, (15.002) aminopyrifen, (15.003) benthazole, (15.004) bethoxazin, (15.005) capsimycin, (15.006) carvone, (15.007) quinomethionate, (15.008) chloroinconazide, (15.009) cufuraneb, (15.010) cyflufenamid, (15.011) cymoxanil, (15.012) cyprosulfamide, (15.013) dipimethitron, (15.014) flutianil, (15.015) flufenoxadiazam, (1 5.016) Flumethylsulfolim, (15.017) Ipflufenoquine, (15.018) Methyl isothiocyanate, (15.019) Mildiomycin, (15.020) Nickel dimethyldithiocarbamate, (15.021) Nitrothalisopropyl, (15.022) Oxyfenthiine, (15.023) Pentachlorophenol and salts, (15.024) Picarburazox, (15.025) Quinovumelin, (15.026) D-tagatose, (15.027) Tebufloquine, (15.028) Tecloftalam, (15.029) Totho Lunifanide, (15.030) 2-(6-benzylpyridin-2-yl)quinazoline, (15.031) 2-[6-(3-fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline, (15.032) 2-phenylphenol and salts, (15.033) 4-amino-5-fluoropyrimidin-2-ol (tautomer: 4-amino-5-fluoropyrimidin-2(1H)-one), (15.034) 4-oxo-4-[(2-phenylethyl)amino]butanoic acid, (15.035) 5-amino-1,3,4-thiadiazole-2-thiazol ol, (15.036) 5-chloro-N'-phenyl-N'-(prop-2-yn-1-yl)thiophene-2-sulfonohydrazide, (15.037) 5-fluoro-2-[(4-fluorobenzyl)oxy]pyrimidin-4-amine, (15.038) 5-fluoro-2-[(4-methylbenzyl)oxy]pyrimidin-4-amine, (15.039) but-3-yn-1-yl {6-[({[(Z)-(1-methyl-1H-tetrazol-5-yl)(phenyl)methylene]amino}oxy)methyl]pyridin-2-yl}carbamate, (15.040) Ethyl (2Z)-3-amino-2-cyano-3-phenylacrylate, (15.041) Phenazine-1-carboxylic acid, (15.042) Propyl 3,4,5-trihydroxybenzoate, (15.043) Quinolin-8-ol, (15.044) Quinolin-8-ol sulfate (2:1), (15.045) 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.046) 1-(5-(fluoromethyl)-6-methyl -pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.047) 1-(5,6-dimethylpyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.048) 1-(6-(difluoromethyl)-5-methoxy-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.049) 1-(6-(difluoromethyl)-5-methyl-pyridin-3-yl)-4,4-difluoro 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.050) 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.051) 2-{2-fluoro-6-[(8-fluoro-2-methylquinolin-3-yl)oxy]phenyl}propan-2-ol, (15.052) 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.053) 3-(4 ,4-Difluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-8-fluoroquinoline, (15.054) 3-(4,4-difluoro-5,5-dimethyl-4,5-dihydrothieno[2,3-c]pyridin-7-yl)quinoline, (15.055) 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.056) 5-bromo-1-(5,6-dimethylpyridin-3-yl)-3,3-dimethyl-3,4-dihydroisoquinoline, (15.057) 8-Fluoro-3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)-quinoline, (15.058) 8-Fluoro-3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-quinoline, (15.059) 8-Fluoro-N-(4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl)quinoline-3-carboxamide, (15.060) 8-Fluoro-N-[(2S)-4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl]quinoline-3-carboxamide N-[(2S)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063A) N-[(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.064) N-[(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.065) N-[(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.066) N-[(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide Fluoroquinoline-3-carboxamide, (15.063B) 2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.063C) (2S)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.063D) (2R)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.064) 1,1-diethyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxo sadiazol-3-yl]phenyl]methyl]urea, (15.065) 1,3-dimethoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.066) 1-[[3-fluoro-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl]methyl]azepan-2-one, (15.067) 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.068) 1-Methoxy-1-methyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.069) 1-Methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.070) 1-Methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.071) 2,2-Difluoro-N-methyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide, (15.072) 3,3-Dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide (15.073) 3-ethyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl] piperidin-2-one, (15.074) 4,4-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl] pyrrolidin-2-one, (15.075) 4,4-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl] isoxazolidin-3-one, (15.076) 4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl Dimethyl carbamate, (15.077) 5,5-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, (15.078) 5-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.079) 1-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}-1H-pyrazole-4-carboxylate ethyl, (15.080) methyl {4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}carbamate, (15.081) N-(1-methylcyclopropyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.082) N-(2,4-difluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.083) N,2-dimethoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.084) N,N-dimethyl-1-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide (15.085) N-[(E)-Methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.086) N-[(E)-N-Methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.087) N-[(Z)-Methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, fluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.088) N-[(Z)-N-methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.089) N-[[2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-3,3,3-trifluoro-propanamide, (15.090) N-[[4-[5-(trifluoromethyl)-1,2, 4-Oxadiazol-3-yl]phenyl]methyl]propanamide, (15.091) N-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]cyclopropanecarboxamide, (15.092) N-{2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}butanamide, (15.093) N-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}cyclopropanecarboxamide, (15.094) N-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}propanamide, (15.095) N-allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]acetamide, (15.096) N-allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.097) N-ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl. other antifungal agents selected from the group consisting of N-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.098) N-methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]cyclopropanecarboxamide, (15.099) N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.100) N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzenecarbothioamide, (15.101) N-methyl-N-phenyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide; wherein said at least one further active compound (C) is different from compound (A) and compound (B).

[0026] The compound (C) is preferably (1.002) difenoconazole, (1.009) fluoxythioconazole, (1.015) ipconazole, (1.017) mefentrifluconazole, (1.024) prothioconazole, (1.026) spiroxamine, (1.027) tebuconazole, (2.001) benzovindiflupyr, (2.002) bixafen, (2.007) fluindapyr, (2.008) fluopyram, (2.010) fluxapyroxad, (2.012) inpirfluxam, (2.014) isoflucipram, (2.016) penflufen, (2.017) penthiopyrad, (2.018) pydiflumetofen, (2.021) sedaxane, (3.003) azoxystrobin, (3.011) fenpicoxamid, (3.014) fluoxastrobin, (3.016) mandestrobin, (3.021) picoxystrobin, (3.022) pyraclostrobin, (3.025) trifloxystrobin, (4.007) Pencycuron, (4.009) Pyriophenone (clazaphenone), (4.011) Thiophanate-methyl, (5.004) Chlorothalonil, (5.011) Dodine, (5.012) Folpet, (5.013) Mancozeb, (5.018) Propineb, (6.005) Isotianil, (7.005) pyrimethanil, (12.003) Metalaxyl, (12.004) Metalaxyl-M (mefenoxam), (13.001) fludioxonil, (13.004) proquinazide, (14.001) Fluazinam, (14.002) Meptyldinocap, (15.010) Cyflufenamid and (15.025) Quinofumelin is selected from. Compound (C) is most preferably (1.015) ipconazole, (1.017) mefentrifluconazole, (1.024) prothioconazole, (1.026) spiroxamine, (1.027) tebuconazole, (2.002) bixafen, (2.008) fluopyram, (2.012) impirfluxam, (2.014) isoflucipram, (2.016) penflufen, (3.011) fenpicoxamid, (3.014) fluoxastrobin, (3.025) trifloxystrobin, (4.007) Pencycuron, (5.004) chlorothalonil, (5.013) mancozeb, (5.018) propineb, (6.005) Isotianil, (12.003) Metalaxyl, (12.004) Metalaxyl-M (mefenoxam), (13.001) fludioxonil, (13.004) proquinazide, (15.010) Cyflufenamid and (15.025) Quinofumelin is selected from.

[0027] The compound combination according to the invention may comprise one, two or even more compounds (C). If a compound (C) is present in the compound combination according to the invention, the compound combination according to the invention preferably comprises one or two compounds (C), more preferably exactly one compound (C).

[0028] In the following, compound (B) and compound (C) will also be referred to briefly by their respective numbers given above, e.g., (1.009) fluoxythioconazole will be referred to briefly as (1.009), (1.014) imazalil sulfate will be referred to briefly as (1.014) and (2.005) cyclobutrifluram will be referred to briefly as (2.005).

[0029] Preferred compound combinations are selected from the group (T1) consisting of the following mixtures: (I-1)+(1.009)、(I-1)+(1.014)、(I-1)+(1.032)、(I-1)+(1.033)、(I-1)+(1.034)、(I-1)+(1.035)、(I-1)+(1.036)、(I-1)+(1.037)、(I-1)+(1.038)、(I-1)+(1.039)、(I-1)+(1.040)、I+(1.041)、(I-1)+(1.042)、(I-1)+(1.043)、(I-1)+(1.044)、(I-1)+(1.045)、(I-1)+(1.046)、(I-1)+(1.047)、(I-1)+(1.048)、(I-1)+(1.049)、(I-1)+(1.050)、I+(1.051)、(I-1)+(1.052)、(I-1)+(1.053)、(I-1)+(1.054)、(I-1)+(1.055)、(I-1)+(1.056)、(I-1)+(1.057)、(I-1)+(1.058)、(I-1)+(1.059)、(I-1)+(1.060)、I+(1.061)、(I-1)+(1.062)、(I-1)+(1.063)、(I-1)+(1.064)、(I-1)+(1.065)、(I-1)+(1.066)、(I-1)+(1.068)、(I-1)+(1.069)、(I-1)+(1.070)、I+(1.071)、(I-1)+(1.073)、(I-1)+(1.074)、(I-1)+(1.075)、(I-1)+(1.076)、(I-1)+(1.077)、(I-1)+(1.078)、 (I-1)+(2.005)、(I-1)+(2.006)、(I-1)+(2.023)、(I-1)+(2.024)、(I-1)+(2.025)、(I-1)+(2.026)、(I-1)+(2.027)、(I-1)+(2.028)、(I-1)+(2.029)、(I-1)+(2.030)、(I-1)+(2.031)、(I-1)+(2.032)、(I-1)+(2.033)、(I-1)+(2.034)、(I-1)+(2.035)、(I-1)+(2.036)、 (I-1)+(3.005)、(I-1)+(3.017)、(I-1)+(3.023)、(I-1)+(3.026)、(I-1)+(3.027)、(I-1)+(3.028)、(I-1)+(3.029)、(I-1)+(3.030)、(I-1)+(3.031)、(I-1)+(3.032)、 (I-1)+(4.013)、(I-1)+(4.014)、(I-1)+(4.015)、(I-1)+(4.016)、(I-1)+(4.017)、(I-1)+(4.018)、(I-1)+(4.019)、(I-1)+(4.020)、(I-1)+(4.021)、(I-1)+(4.022)、(I-1)+(4.023)、(I-1)+(4.024)、(I-1)+(4.025)、(I-1)+(4.026)、(I-1)+(4.027)、(I-1)+(4.028)、 (I-1)+(5.001)、(I-1)+(5.005)、(I-1)+(5.006)、(I-1)+(5.007)、(I-1)+(5.008)、(I-1)+(5.009)、(I-1)+(5.016)、(I-1)+(5.017)、(I-1)+(5.019)、(I-1)+(5.023)、 (I-1)+(6.003)、(I-1)+(6.004)、(I-1)+(6.008)、 (I-1)+(7.003)、 (I-1)+(9.008)、(I-1)+(9.009)、 (I-1)+(10.005)、(I-1)+(10.006)、(I-1)+(10.008)、(I-1)+(10.009)、(I-1)+(10.010)、(I-1)+(10.011)、(I-1)+(10.012)、(I-1)+(10.013)、(I-1)+(10.014)、(I-1)+(10.015)、(I-1)+(10.016)、(I-1)+(10.017)、(I-1)+(10.018)、(I-1)+(10.019)、 (I-1)+(15.001)、(I-1)+(15.003)、(I-1)+(15.004)、(I-1)+(15.005)、(I-1)+(15.006)、(I-1)+(15.008)、(I-1)+(15.009)、(I-1)+(15.012)、(I-1)+(15.015)、(I-1)+(15.016)、(I-1)+(15.018)、(I-1)+(15.019)、(I-1)+(15.020)、(I-1)+(15.021)、(I-1)+(15.022)、(I-1)+(15.023)、(I-1)+(15.026)、(I-1)+(15.029)、(I-1)+(15.030)、(I-1)+(15.031)、(I-1)+(15.032)、(I-1)+(15.033)、(I-1)+(15.034)、(I-1)+(15.035)、(I-1)+(15.036)、(I-1)+(15.037)、(I-1)+(15.038)、(I-1)+(15.039)、(I-1)+(15.040)、(I-1)+(15.041)、(I-1)+(15.042)、(I-1)+(15.043)、(I-1)+(15.044)、(I-1)+(15.045)、(I-1)+(15.046)、(I-1)+(15.047)、(I-1)+(15.048)、(I-1)+(15.049)、(I-1)+(15.050)、(I-1)+(15.051)、(I-1)+(15.052)、(I-1)+(15.053)、(I-1)+(15.054)、(I-1)+(15.055)、(I-1)+(15.056)、(I-1)+(15.057)、(I-1)+(15.058)、(I-1)+(15.059)、(I-1)+(15.060)、(I-1)+(15.061)、(I-1)+(15.062)、(I-1)+(15.063)、(I-1)+(15.063A)、(I-1)+(15.063B)、(I-1)+(15.063C)、(I-1)+(15.063D)、(I-1)+(15.064)、(I-1)+(15.065)、(I-1)+(15.066)、(I-1)+(15.067)、(I-1)+(15.068)、(I-1)+(15.069)、(I-1)+(15.070)、(I-1)+(15.071)、(I-1)+(15.072)、(I-1)+(15.073), (I-1)+(15.074), (I-1)+(15.075), (I-1)+(15.076), (I-1)+(15.077), (I-1)+(15.078), (I-1)+(15.079), (I-1)+(15.0) 80), (I-1)+(15.081), (I-1)+(15.082), (I-1)+(15.083), (I-1)+(15.084), (I-1)+(15.085), (I-1)+(15.086), (I-1)+(15.087) ), (I-1)+(15.088), (I-1)+(15.089), (I-1)+(15.090), (I-1)+(15.091), (I-1)+(15.092), (I-1)+(15.093), (I-1)+(15.094) , (I-1)+(15.095), (I-1)+(15.096), (I-1)+(15.097), (I-1)+(15.098), (I-1)+(15.099), (I-1)+(15.100), (I-1)+(15.101),. (I-1)+(A1.01), (I-1)+(A1.06), (I-1)+(B1.01), (I-1)+(B1.02), (I-1)+(B1.03) , (I-1)+(B1.04), (I-1)+(B1.07), (I-1)+(B1.08), (I-1)+(B1.19), (I-1)+(B1.25 ), (I-1)+(B2.01), (I-1)+(B2.54), (I-1)+(C1.05), (I-1)+(C1.06), (I-1)+(C1.1 6), (I-1)+(C1.17), (I-1)+(C1.23), (I-1)+(C1.25), (I-1)+(C1.26), (I-1)+(G1).

[0030] Preferred compound combinations are also selected from the group (T2) consisting of the following mixtures: (I-2)+(1.009)、(I-2)+(1.014)、(I-2)+(1.032)、(I-2)+(1.033)、(I-2)+(1.034)、(I-2)+(1.035)、(I-2)+(1.036)、(I-2)+(1.037)、(I-2)+(1.038)、(I-2)+(1.039)、(I-2)+(1.040)、I+(1.041)、(I-2)+(1.042)、(I-2)+(1.043)、(I-2)+(1.044)、(I-2)+(1.045)、(I-2)+(1.046)、(I-2)+(1.047)、(I-2)+(1.048)、(I-2)+(1.049)、(I-2)+(1.050)、I+(1.051)、(I-2)+(1.052)、(I-2)+(1.053)、(I-2)+(1.054)、(I-2)+(1.055)、(I-2)+(1.056)、(I-2)+(1.057)、(I-2)+(1.058)、(I-2)+(1.059)、(I-2)+(1.060)、I+(1.061)、(I-2)+(1.062)、(I-2)+(1.063)、(I-2)+(1.064)、(I-2)+(1.065)、(I-2)+(1.066)、(I-2)+(1.068)、(I-2)+(1.069)、(I-2)+(1.070)、I+(1.071)、(I-2)+(1.073)、(I-2)+(1.074)、(I-2)+(1.075)、(I-2)+(1.076)、(I-2)+(1.077)、(I-2)+(1.078)、 (I-2)+(2.005)、(I-2)+(2.006)、(I-2)+(2.023)、(I-2)+(2.024)、(I-2)+(2.025)、(I-2)+(2.026)、(I-2)+(2.027)、(I-2)+(2.028)、(I-2)+(2.029)、(I-2)+(2.030)、(I-2)+(2.031)、(I-2)+(2.032)、(I-2)+(2.033)、(I-2)+(2.034)、(I-2)+(2.035)、(I-2)+(2.036)、 (I-2)+(3.005)、(I-2)+(3.017)、(I-2)+(3.023)、(I-2)+(3.026)、(I-2)+(3.027)、(I-2)+(3.028)、(I-2)+(3.029)、(I-2)+(3.030)、(I-2)+(3.031)、(I-2)+(3.032)、 (I-2)+(4.013)、(I-2)+(4.014)、(I-2)+(4.015)、(I-2)+(4.016)、(I-2)+(4.017)、(I-2)+(4.018)、(I-2)+(4.019)、(I-2)+(4.020)、(I-2)+(4.021)、(I-2)+(4.022)、(I-2)+(4.023)、(I-2)+(4.024)、(I-2)+(4.025)、(I-2)+(4.026)、(I-2)+(4.027)、(I-2)+(4.028)、 (I-2)+(5.001)、(I-2)+(5.005)、(I-2)+(5.006)、(I-2)+(5.007)、(I-2)+(5.008)、(I-2)+(5.009)、(I-2)+(5.016)、(I-2)+(5.017)、(I-2)+(5.019)、(I-2)+(5.023)、 (I-2)+(6.003)、(I-2)+(6.004)、(I-2)+(6.008)、 (I-2)+(7.003)、 (I-2)+(9.008)、(I-2)+(9.009)、 (I-2)+(10.005)、(I-2)+(10.006)、(I-2)+(10.008)、(I-2)+(10.009)、(I-2)+(10.010)、(I-2)+(10.011)、(I-2)+(10.012)、(I-2)+(10.013)、(I-2)+(10.014)、(I-2)+(10.015)、(I-2)+(10.016)、(I-2)+(10.017)、(I-2)+(10.018)、(I-2)+(10.019)、 (I-2)+(15.001)、(I-2)+(15.003)、(I-2)+(15.004)、(I-2)+(15.005)、(I-2)+(15.006)、(I-2)+(15.008)、(I-2)+(15.009)、(I-2)+(15.012)、(I-2)+(15.015)、(I-2)+(15.016)、(I-2)+(15.018)、(I-2)+(15.019)、(I-2)+(15.020)、(I-2)+(15.021)、(I-2)+(15.022)、(I-2)+(15.023)、(I-2)+(15.026)、(I-2)+(15.029)、(I-2)+(15.030)、(I-2)+(15.031)、(I-2)+(15.032)、(I-2)+(15.033)、(I-2)+(15.034)、(I-2)+(15.035)、(I-2)+(15.036)、(I-2)+(15.037)、(I-2)+(15.038)、(I-2)+(15.039)、(I-2)+(15.040)、(I-2)+(15.041)、(I-2)+(15.042)、(I-2)+(15.043)、(I-2)+(15.044)、(I-2)+(15.045)、(I-2)+(15.046)、(I-2)+(15.047)、(I-2)+(15.048)、(I-2)+(15.049)、(I-2)+(15.050)、(I-2)+(15.051)、(I-2)+(15.052)、(I-2)+(15.053)、(I-2)+(15.054)、(I-2)+(15.055)、(I-2)+(15.056)、(I-2)+(15.057)、(I-2)+(15.058)、(I-2)+(15.059)、(I-2)+(15.060)、(I-2)+(15.061)、(I-2)+(15.062)、(I-2)+(15.063)、(I-2)+(15.063A)、(I-2)+(15.063B)、(I-2)+(15.063C)、(I-2)+(15.063D)、(I-2)+(15.064)、(I-2)+(15.065)、(I-2)+(15.066)、(I-2)+(15.067)、(I-2)+(15.068)、(I-2)+(15.069)、(I-2)+(15.070)、(I-2)+(15.071)、(I-2)+(15.072)、(I-2)+(15.073), (I-2)+(15.074), (I-2)+(15.075), (I-2)+(15.076), (I-2)+(15.077), (I-2)+(15.078), (I-2)+(15.079), (I-2)+(15.0) 80), (I-2)+(15.081), (I-2)+(15.082), (I-2)+(15.083), (I-2)+(15.084), (I-2)+(15.085), (I-2)+(15.086), (I-2)+(15.087) ), (I-2)+(15.088), (I-2)+(15.089), (I-2)+(15.090), (I-2)+(15.091), (I-2)+(15.092), (I-2)+(15.093), (I-2)+(15.094) , (I-2)+(15.095), (I-2)+(15.096), (I-2)+(15.097), (I-2)+(15.098), (I-2)+(15.099), (I-2)+(15.100), (I-2)+(15.101),. (I-2)+(A1.01), (I-2)+(A1.06), (I-2)+(B1.01), (I-2)+(B1.02), (I-2)+(B1.03) , (I-2)+(B1.04), (I-2)+(B1.07), (I-2)+(B1.08), (I-2)+(B1.19), (I-2)+(B1.25 ), (I-2)+(B2.01), (I-2)+(B2.54), (I-2)+(C1.05), (I-2)+(C1.06), (I-2)+(C1.1 6), (I-2)+(C1.17), (I-2)+(C1.23), (I-2)+(C1.25), (I-2)+(C1.26), (I-2)+(G1).

[0031] Preferred compound combinations are also selected from the group (T3) consisting of the following mixtures: (I-1)+(I-2)+(1.009)、(I-1)+(I-2)+(1.014)、(I-1)+(I-2)+(1.032)、(I-1)+(I-2)+(1.033)、(I-1)+(I-2)+(1.034)、(I-1)+(I-2)+(1.035)、(I-1)+(I-2)+(1.036)、(I-1)+(I-2)+(1.037)、(I-1)+(I-2)+(1.038)、(I-1)+(I-2)+(1.039)、(I-1)+(I-2)+(1.040)、I+(1.041)、(I-1)+(I-2)+(1.042)、(I-1)+(I-2)+(1.043)、(I-1)+(I-2)+(1.044)、(I-1)+(I-2)+(1.045)、(I-1)+(I-2)+(1.046)、(I-1)+(I-2)+(1.047)、(I-1)+(I-2)+(1.048)、(I-1)+(I-2)+(1.049)、(I-1)+(I-2)+(1.050)、I+(1.051)、(I-1)+(I-2)+(1.052)、(I-1)+(I-2)+(1.053)、(I-1)+(I-2)+(1.054)、(I-1)+(I-2)+(1.055)、(I-1)+(I-2)+(1.056)、(I-1)+(I-2)+(1.057)、(I-1)+(I-2)+(1.058)、(I-1)+(I-2)+(1.059)、(I-1)+(I-2)+(1.060)、I+(1.061)、(I-1)+(I-2)+(1.062)、(I-1)+(I-2)+(1.063)、(I-1)+(I-2)+(1.064)、(I-1)+(I-2)+(1.065)、(I-1)+(I-2)+(1.066)、(I-1)+(I-2)+(1.068)、(I-1)+(I-2)+(1.069)、(I-1)+(I-2)+(1.070)、I+(1.071)、(I-1)+(I-2)+(1.073)、(I-1)+(I-2)+(1.074)、(I-1)+(I-2)+(1.075)、(I-1)+(I-2)+(1.076)、(I-1)+(I-2)+(1.077)、(I-1)+(I-2)+(1.078)、 (I-1)+(I-2)+(2.005)、(I-1)+(I-2)+(2.006)、(I-1)+(I-2)+(2.023)、(I-1)+(I-2)+(2.024)、(I-1)+(I-2)+(2.025)、(I-1)+(I-2)+(2.026)、(I-1)+(I-2)+(2.027)、(I-1)+(I-2)+(2.028)、(I-1)+(I-2)+(2.029)、(I-1)+(I-2)+(2.030)、(I-1)+(I-2)+(2.031)、(I-1)+(I-2)+(2.032)、(I-1)+(I-2)+(2.033)、(I-1)+(I-2)+(2.034)、(I-1)+(I-2)+(2.035)、(I-1)+(I-2)+(2.036)、 (I-1)+(I-2)+(3.005)、(I-1)+(I-2)+(3.017)、(I-1)+(I-2)+(3.023)、(I-1)+(I-2)+(3.026)、(I-1)+(I-2)+(3.027)、(I-1)+(I-2)+(3.028)、(I-1)+(I-2)+(3.029)、(I-1)+(I-2)+(3.030)、(I-1)+(I-2)+(3.031)、(I-1)+(I-2)+(3.032)、 (I-1)+(I-2)+(4.013)、(I-1)+(I-2)+(4.014)、(I-1)+(I-2)+(4.015)、(I-1)+(I-2)+(4.016)、(I-1)+(I-2)+(4.017)、(I-1)+(I-2)+(4.018)、(I-1)+(I-2)+(4.019)、(I-1)+(I-2)+(4.020)、(I-1)+(I-2)+(4.021)、(I-1)+(I-2)+(4.022)、(I-1)+(I-2)+(4.023)、(I-1)+(I-2)+(4.024)、(I-1)+(I-2)+(4.025)、(I-1)+(I-2)+(4.026)、(I-1)+(I-2)+(4.027)、(I-1)+(I-2)+(4.028)、 (I-1)+(I-2)+(5.001)、(I-1)+(I-2)+(5.005)、(I-1)+(I-2)+(5.006)、(I-1)+(I-2)+(5.007)、(I-1)+(I-2)+(5.008)、(I-1)+(I-2)+(5.009)、(I-1)+(I-2)+(5.016)、(I-1)+(I-2)+(5.017)、(I-1)+(I-2)+(5.019)、(I-1)+(I-2)+(5.023)、 (I-1)+(I-2)+(6.003)、(I-1)+(I-2)+(6.004)、(I-1)+(I-2)+(6.008)、 (I-1)+(I-2)+(7.003)、 (I-1)+(I-2)+(9.008)、(I-1)+(I-2)+(9.009)、 (I-1)+(I-2)+(10.005)、(I-1)+(I-2)+(10.006)、(I-1)+(I-2)+(10.008)、(I-1)+(I-2)+(10.009)、(I-1)+(I-2)+(10.010)、(I-1)+(I-2)+(10.011)、(I-1)+(I-2)+(10.012)、(I-1)+(I-2)+(10.013)、(I-1)+(I-2)+(10.014)、(I-1)+(I-2)+(10.015)、(I-1)+(I-2)+(10.016)、(I-1)+(I-2)+(10.017)、(I-1)+(I-2)+(10.018)、(I-1)+(I-2)+(10.019)、 (I-1)+(I-2)+(15.001)、(I-1)+(I-2)+(15.003)、(I-1)+(I-2)+(15.004)、(I-1)+(I-2)+(15.005)、(I-1)+(I-2)+(15.006)、(I-1)+(I-2)+(15.008)、(I-1)+(I-2)+(15.009)、(I-1)+(I-2)+(15.012)、(I-1)+(I-2)+(15.015)、(I-1)+(I-2)+(15.016)、(I-1)+(I-2)+(15.018)、(I-1)+(I-2)+(15.019)、(I-1)+(I-2)+(15.020)、(I-1)+(I-2)+(15.021)、(I-1)+(I-2)+(15.022)、(I-1)+(I-2)+(15.023)、(I-1)+(I-2)+(15.026)、(I-1)+(I-2)+(15.029)、(I-1)+(I-2)+(15.030)、(I-1)+(I-2)+(15.031)、(I-1)+(I-2)+(15.032)、(I-1)+(I-2)+(15.033)、(I-1)+(I-2)+(15.034)、(I-1)+(I-2)+(15.035)、(I-1)+(I-2)+(15.036)、(I-1)+(I-2)+(15.037)、(I-1)+(I-2)+(15.038)、(I-1)+(I-2)+(15.039)、(I-1)+(I-2)+(15.040)、(I-1)+(I-2)+(15.041)、(I-1)+(I-2)+(15.042)、(I-1)+(I-2)+(15.043)、(I-1)+(I-2)+(15.044)、(I-1)+(I-2)+(15.045)、(I-1)+(I-2)+(15.046)、(I-1)+(I-2)+(15.047)、(I-1)+(I-2)+(15.048)、(I-1)+(I-2)+(15.049)、(I-1)+(I-2)+(15.050)、(I-1)+(I-2)+(15.051)、(I-1)+(I-2)+(15.052)、(I-1)+(I-2)+(15.053)、(I-1)+(I-2)+(15.054)、(I-1)+(I-2)+(15.055)、(I-1)+(I-2)+(15.056)、(I-1)+(I-2)+(15.057)、(I-1)+(I-2)+(15.058)、(I-1)+(I-2)+(15.059)、(I-1)+(I-2)+(15.060)、(I-1)+(I-2)+(15.061)、(I-1)+(I-2)+(15.062)、(I-1)+(I-2)+(15.063)、(I-1)+(I-2)+(15.063A)、(I-1)+(I-2)+(15.063B)、(I-1)+(I-2)+(15.063C)、(I-1)+(I-2)+(15.063D)、(I-1)+(I-2)+(15.064)、(I-1)+(I-2)+(15.065)、(I-1)+(I-2)+(15.066)、(I-1)+(I-2)+(15.067)、(I-1)+(I-2)+(15.068)、(I-1)+(I-2)+(15.069)、(I-1)+(I-2)+(15.070)、(I-1)+(I-2)+(15.071)、(I-1)+(I-2)+(15.072)、(I-1)+(I-2)+(15.073)、(I-1)+(I-2)+(15.074)、(I-1)+(I-2)+(15.075)、(I-1)+(I-2)+(15.076)、(I-1)+(I-2)+(15.077)、(I-1)+(I-2)+(15.078)、(I-1)+(I-2)+(15.079)、(I-1)+(I-2)+(15.080)、(I-1)+(I-2)+(15.081)、(I-1)+(I-2)+(15.082)、(I-1)+(I-2)+(15.083)、(I-1)+(I-2)+(15.084)、(I-1)+(I-2)+(15.085)、(I-1)+(I-2)+(15.086)、(I-1)+(I-2)+(15.087)、(I-1)+(I-2)+(15.088)、(I-1)+(I-2)+(15.089)、(I-1)+(I-2)+(15.090)、(I-1)+(I-2)+(15.091)、(I-1)+(I-2)+(15.092)、(I-1)+(I-2)+(15.093)、(I-1)+(I-2)+(15.094)、(I-1)+(I-2)+(15.095)、(I-1)+(I-2)+(15.096)、(I-1)+(I-2)+(15.097)、(I-1)+(I-2)+(15.098)、(I-1)+(I-2)+(15.099)、(I-1)+(I-2)+(15.100)、(I-1)+(I-2)+(15.101)、. (I-1)+(I-2)+(A1.01), (I-1)+(I-2)+(A1.06), (I-1)+(I-2)+(B1.01), (I-1)+(I-2)+(B1.02), (I-1)+(I-2)+(B1.03) , (I-1)+(I-2)+(B1.04), (I-1)+(I-2)+(B1.07), (I-1)+(I-2)+(B1.08), (I-1)+(I-2)+(B1.19), (I-1)+(I-2)+(B1.25 ), (I-1)+(I-2)+(B2.01), (I-1)+(I-2)+(B2.54), (I-1)+(I-2)+(C1.05), (I-1)+(I-2)+(C1.06), (I-1)+(I-2)+(C1.1 6), (I-1)+(I-2)+(C1.17), (I-1)+(I-2)+(C1.23), (I-1)+(I-2)+(C1.25), (I-1)+(I-2)+(C1.26), (I-1)+(I-2)+(G1).

[0032] More preferred compound combinations are selected from the group (T1A) consisting of the following mixtures: (I-1)+(1.009), (I-1)+(1.014), (I-1)+(2.005), (I-1)+(2.006), (I-1)+(3.005), (I-1)+(3.017), (I-1)+( 3.023), (I-1)+(5.001), (I-1)+(5.005), (I-1)+(5.006), (I-1)+(5.007), (I-1)+(5.008), (I-1)+(5.009), ( I-1)+(5.016), (I-1)+(5.017), (I-1)+(5.019), (I-1)+(6.003), (I-1)+(6.004), (I-1)+(6.008), (I-1)+(7. 003), (I-1)+(10.005), (I-1)+(10.006), (I-1)+(15.001), (I-1)+(15.003), (I-1)+(15.004), (I-1)+(15.00) 5), (I-1)+(15.006), (I-1)+(15.008), (I-1)+(15.009), (I-1)+(15.012), (I-1)+(15.015), (I-1)+(15.016) ), (I-1)+(15.018), (I-1)+(15.019), (I-1)+(15.020), (I-1)+(15.021), (I-1)+(15.022), (I-1)+(15.023), (I-1)+(15.026), (I-1)+(15.029), (I-1)+(15.045), (I-1)+(15.050), (I-1)+(15.059), (I-1)+(15.060), (I -1)+(15.062), (I-1)+(15.063), (I-1)+(15.063A), (I-1)+(15.063B), (I-1)+(15.063C), (I-1)+(15.063D).

[0033] More preferred compound combinations are also selected from the group (T2A) consisting of the following mixtures: (I-2)+(1.009), (I-2)+(1.014), (I-2)+(2.005), (I-2)+(2.006), (I-2)+(3.005), (I-2)+(3.017), (I-2)+( 3.023), (I-2)+(5.001), (I-2)+(5.005), (I-2)+(5.006), (I-2)+(5.007), (I-2)+(5.008), (I-2)+(5.009), ( I-2)+(5.016), (I-2)+(5.017), (I-2)+(5.019), (I-2)+(6.003), (I-2)+(6.004), (I-2)+(6.008), (I-2)+(7. 003), (I-2)+(10.005), (I-2)+(10.006), (I-2)+(15.001), (I-2)+(15.003), (I-2)+(15.004), (I-2)+(15.00) 5), (I-2)+(15.006), (I-2)+(15.008), (I-2)+(15.009), (I-2)+(15.012), (I-2)+(15.015), (I-2)+(15.016) ), (I-2)+(15.018), (I-2)+(15.019), (I-2)+(15.020), (I-2)+(15.021), (I-2)+(15.022), (I-2)+(15.023), (I-2)+(15.026), (I-2)+(15.029), (I-2)+(15.045), (I-2)+(15.050), (I-2)+(15.059), (I-2)+(15.060), (I -2)+(15.062), (I-2)+(15.063), (I-2)+(15.063A), (I-2)+(15.063B), (I-2)+(15.063C), (I-2)+(15.063D).

[0034] More preferred compound combinations are also selected from the group (T3A) consisting of the following mixtures: (I-1)+(I-2)+(1.009)、(I-1)+(I-2)+(1.014)、(I-1)+(I-2)+(2.005)、(I-1)+(I-2)+(2.006)、(I-1)+(I-2)+(3.005)、(I-1)+(I-2)+(3.017)、(I-1)+(I-2)+(3.023)、(I-1)+(I-2)+(5.001)、(I-1)+(I-2)+(5.005)、(I-1)+(I-2)+(5.006)、(I-1)+(I-2)+(5.007)、(I-1)+(I-2)+(5.008)、(I-1)+(I-2)+(5.009)、(I-1)+(I-2)+(5.016)、(I-1)+(I-2)+(5.017)、(I-1)+(I-2)+(5.019)、(I-1)+(I-2)+(6.003)、(I-1)+(I-2)+(6.004)、(I-1)+(I-2)+(6.008)、(I-1)+(I-2)+(7.003)、(I-1)+(I-2)+(10.005)、(I-1)+(I-2)+(10.006)、(I-1)+(I-2)+(15.001)、(I-1)+(I-2)+(15.003)、(I-1)+(I-2)+(15.004)、(I-1)+(I-2)+(15.005)、(I-1)+(I-2)+(15.006)、(I-1)+(I-2)+(15.008)、(I-1)+(I-2)+(15.009)、(I-1)+(I-2)+(15.012)、(I-1)+(I-2)+(15.015)、(I-1)+(I-2)+(15.016)、(I-1)+(I-2)+(15.018)、(I-1)+(I-2)+(15.019)、(I-1)+(I-2)+(15.020)、(I-1)+(I-2)+(15.021)、(I-1)+(I-2)+(15.022)、(I-1)+(I-2)+(15.023)、(I-1)+(I-2)+(15.026)、(I-1)+(I-2)+(15.029)、(I-1)+(I-2)+(15.045)、(I-1)+(I-2)+(15.050)、(I-1)+(I-2)+(15.059)、(I-1)+(I-2)+(15.060)、(I-1)+(I-2)+(15.062)、(I-1)+(I-2)+(15.063)、(I-1)+(I-2)+(15.063A)、(I-1)+(I-2)+(15.063B), (I-1)+(I-2)+(15.063C), (I-1)+(I-2)+(15.063D). .

[0035] Even more preferred compound combinations are selected from the group (T1B) consisting of the following mixtures: (I-1)+(1.009), (I-1)+(2.005), (I-1)+(3.017), (I-1)+(15.015), (I-1)+(15.016), (I -1)+(15.045), (I-1)+(15.050), (I-1)+(15.060), (I-1)+(15.063A), (I-1)+(15.063D).

[0036] Even more preferred compound combinations are also selected from the group (T2B) consisting of the following mixtures: (I-2)+(1.009), (I-2)+(2.005), (I-2)+(3.017), (I-2)+(15.015), (I-2)+(15.016), (I -2)+(15.045), (I-2)+(15.050), (I-2)+(15.060), (I-2)+(15.063A), (I-2)+(15.063D).

[0037] Even more preferred compound combinations are also selected from the group (T3B) consisting of the following mixtures: (I-1)+(I-2)+(1.009), (I-1)+(I-2)+(2.005), (I-1)+(I-2)+(3.017), (I-1)+(I-2)+(15.015), (I-1)+(I-2)+(15.016), (I -1)+(I-2)+(15.045), (I-1)+(I-2)+(15.050), (I-1)+(I-2)+(15.060), (I-1)+(I-2)+(15.063A), (I-1)+(I-2)+(15.063D).

[0038] Even more preferred compound combinations are selected from the group (T1C) consisting of the following combinations: (I-1)+(3.017), (I-2)+(3.017), (I-1)+(I-2)+(3.017).

[0039] Most preferred is the compound combination (I-1)+(3.017), i.e. a mixture of the compounds (I-1) methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate and (3.017) methallylpicoxamide.

[0040] In the combinations according to the invention comprising mixtures of (I-1) and (I-2), and in particular in the mixtures of groups (T3), (T3A), (T3B) and (T1C), the compounds (I-1) and (I-2) can be present in a wide range of effective weight ratios of (I-1):(I-2), for example in the range of 1,000,000:1 to 1:100, preferably 1,000,000:1 to 1:50, more preferably 1,000,000:1 to 1:20, and most preferably 100,000:1 to 1:20. Further ratios of (I-1):(I-2) which can be used according to the invention are 95:1 to 1:95, 90:1 to 1:90, 85:1 to 1:85, 80:1 to 1:80, 75:1 to 1:75, 70:1 to 1:70, 65:1 to 1:65, 60:1 to 1:60, 55:1 to 1:55, 45:1 to 1:45, 40:1 to 1:40, 35:1 to 1:35, 30:1 to 1:30, 25:1 to 1:25, 15:1 to 1:15, 10:1 to 1:10, 5:1 to 1:5, 4:1 to 1:4, 3:1 to 1:3, 2:1 to 1:2, with the given order of increasing preference.

[0041] Further ratios of (I-1):(I-2) that can be used according to the invention are 1,000,000:1 to 1:1, 1,00,000:1 to 1:1, 10,000:1 to 1:1, 1,000:1 to 1:1, 100:1 to 1:1, 95:1 to 1:1, 90:1 to 1:1, 85:1 to 1:1, 80:1 to 1:1, 75: 1~1:1, 70:1~1:1, 65:1~1:1, 60:1~1:1, 55:1~1:1, 45:1~1:1, 40:1~1:1, 35:1~1:1, 30:1~1:1, 25:1~1:1, 15:1~1:1, 10:1~1:1, 5:1~1:1, 4:1~1:1, 3:1~1:1, 2:1~1:1.

[0042] Further ratios of (I-1):(I-2) which can be used according to the invention are 1:1 to 1:95, 1:1 to 1:90, 1:1 to 1:85, 1:1 to 1:80, 1:1 to 1:75, 1:1 to 1:70, 1:1 to 1:65, 1:1 to 1:60, 1:1 to 1:55, 1:1 to 1:45, 1:1 to 1:40, 1:1 to 1:35, 1:1 to 1:30, 1:1 to 1:25, 1:1 to 1:15, 1:1 to 1:10, 1:1 to 1:5, 1:1 to 1:4, 1:1 to 1:3, 1:1 to 1:2.

[0043] In the combination according to the invention, compounds (A) and (B) may be present in a wide range of effective weight ratios of A:B, for example, 5,000:1 to 1:5,000, 2,500:1 to 1:2,500, 2,000:1 to 1:2,000, 1,500:1 to 1:1,500, 1,000:1 to 1:1,000, 500:1 to 1:500, 400:1 to 1:400, 300:1 to 1:300, 250:1 to 1:250, 200:1 to 1:200, 150:1 to 1:150, 100:1 to 1:100, preferably 50:1 to 1:50 weight ratio, most preferably 20:1 to 1:20 weight ratio. Further ratios of A:B which can be used according to the invention are 95:1 to 1:95, 90:1 to 1:90, 85:1 to 1:85, 80:1 to 1:80, 75:1 to 1:75, 70:1 to 1:70, 65:1 to 1:65, 60:1 to 1:60, 55:1 to 1:55, 45:1 to 1:45, 40:1 to 1:40, 35:1 to 1:35, 30:1 to 1:30, 25:1 to 1:25, 15:1 to 1:15, 10:1 to 1:10, 5:1 to 1:5, 4:1 to 1:4, 3:1 to 1:3, 2:1 to 1:2, with the given order of increasing preference.

[0044] Further ratios of A:B that can be used according to the invention are 5,000:1 to 1:1, 2,500:1 to 1:1, 2,000:1 to 1:1, 1,500:1 to 1:1, 1,000:1 to 1:1, 500:1 to 1:1, 250:1 to 1:1, 100:1 to 1:1, 95:1 to 1:1, 90:1 to 1:1, 85:1 to 1:1, 80:1 ~1:1, 75:1~1:1, 70:1~1:1, 65:1~1:1, 60:1~1:1, 55:1~1:1, 45:1~1:1, 40:1~1:1, 35:1~1:1, 30:1~1:1, 25:1~1:1, 15:1~1:1, 10:1~1:1, 5:1~1:1, 4:1~1:1, 3:1~1:1, 2:1~1:1.

[0045] Further ratios of A:B that can be used according to the invention are 1:1 to 1:5,000, 1:1 to 1:2,500, 1:1 to 1:2,000, 1:1 to 1:1,500, 1:1 to 1:1,000, 1:1 to 1:500, 1:1 to 1:250, 1:1 to 1:100, 1:1 to 1:95, 1:1 to 1:90, 1:1 to 1:85, 1:1 to 1:80, 1:1~1:75, 1:1~1:70, 1:1~1:65, 1:1~1:60, 1:1~1:55, 1:1~1:45, 1:1~1:40, 1:1~1:35, 1:1~1:30, 1:1~1:25, 1:1~1:15, 1:1~1:10, 1:1~1:5, 1:1~1:4, 1:1~1:3, 1:1~1:2.

[0046] In the combinations according to the invention comprising at least one further antifungally active compound as defined above as compound (C), the compounds (A) and (C) may be present in a wide range of effective weight ratios of A:C, for example from 5,000:1 to 1:5,000, 2,500:1 to 1:2,500, 2,000:1 to 1:2,000, 1,500:1 to 1:1,500, 1,000:1 to 1:1,000, 500:1 to 1:500, 400:1 to 1:400, 300:1 to 1:300, 250:1 to 1:250, 200:1 to 1:200, 150:1 to 1:150, 100:1 to 1:100, preferably in a weight ratio of 50:1 to 1:50, most preferably in a weight ratio of 20:1 to 1:20. Further ratios of A:C which can be used according to the invention are 95:1 to 1:95, 90:1 to 1:90, 85:1 to 1:85, 80:1 to 1:80, 75:1 to 1:75, 70:1 to 1:70, 65:1 to 1:65, 60:1 to 1:60, 55:1 to 1:55, 45:1 to 1:45, 40:1 to 1:40, 35:1 to 1:35, 30:1 to 1:30, 25:1 to 1:25, 15:1 to 1:15, 10:1 to 1:10, 5:1 to 1:5, 4:1 to 1:4, 3:1 to 1:3, 2:1 to 1:2, with the given order of increasing preference.

[0047] Further ratios of A:C that can be used according to the invention are 5,000:1 to 1:1, 2,500:1 to 1:1, 2,000:1 to 1:1, 1,500:1 to 1:1, 1,000:1 to 1:1, 500:1 to 1:1, 250:1 to 1:1, 100:1 to 1:1, 95:1 to 1:1, 90:1 to 1:1, 85:1 to 1:1, 80:1 ~1:1, 75:1~1:1, 70:1~1:1, 65:1~1:1, 60:1~1:1, 55:1~1:1, 45:1~1:1, 40:1~1:1, 35:1~1:1, 30:1~1:1, 25:1~1:1, 15:1~1:1, 10:1~1:1, 5:1~1:1, 4:1~1:1, 3:1~1:1, 2:1~1:1.

[0048] Further ratios of A:C that can be used according to the invention are 1:1 to 1:5,000, 1:1 to 1:2,500, 1:1 to 1:2,000, 1:1 to 1:1,500, 1:1 to 1:1,000, 1:1 to 1:500, 1:1 to 1:250, 1:1 to 1:100, 1:1 to 1:95, 1:1 to 1:90, 1:1 to 1:85, 1:1 to 1:80, 1:1~1:75, 1:1~1:70, 1:1~1:65, 1:1~1:60, 1:1~1:55, 1:1~1:45, 1:1~1:40, 1:1~1:35, 1:1~1:30, 1:1~1:25, 1:1~1:15, 1:1~1:10, 1:1~1:5, 1:1~1:4, 1:1~1:3, 1:1~1:2.

[0049] In the combinations according to the invention comprising at least one further antifungally active compound defined above as compound (C), furthermore, compounds (B) and (C) can be present in a wide range of effective weight ratios B:C, the respective weight ratios being derived from the automatically selected weight ratios A:B and A:C.

[0050] When more than one compound (C), e.g. two or three, are present, the weight ratio refers to the total amount of compounds (C), i.e. the sum of the amounts of each compound (C) present in the combination. This applies mutatis mutandis when a mixture of two compounds (A), i.e. (I-1) and (I-2), is present.

[0051] Isomers As already outlined above, compounds (I-1) and (I-2) may exist in different stereoisomeric forms. Depending on the nature of the substituents of compounds (B) and (C), compounds (B) and (C) may also exist in the compound combination of the present invention in different stereoisomeric forms. These stereoisomers are, for example, enantiomers, diastereomers, atropisomers or geometric isomers. Thus, the present invention encompasses both pure stereoisomers and any mixtures of these isomers. If a compound can exist in two or more tautomeric forms in equilibrium, referring to a compound by one tautomer shall be considered to include all tautomers. If a compound can exist in stereoisomeric and / or tautomeric forms, it is understood that such compounds include, where applicable, the corresponding isomers and / or tautomers or mixtures thereof in the above and below of this specification, even if these are not specifically mentioned in each case.

[0052] Salt / N-oxide Depending on the nature of the substituents, the compounds present in the compound combinations of the invention may exist in the form of free compounds and / or their solvates and / or pesticidal active salts and / or N-oxides.

[0053] Pesticidal active salts include acid addition salts of inorganic and organic acids and salts of customary bases. Examples of inorganic acids are hydrohalic acids such as hydrofluoric acid, hydrochloric acid, hydrobromic acid and hydrogen iodide, sulfuric acid, phosphoric acid and nitric acid, as well as acid salts such as sodium bisulfate and potassium bisulfate. Useful organic acids include, for example, formic acid, carbonic acid and alkanoic acids such as acetic acid, trifluoroacetic acid, trichloroacetic acid and propionic acid, as well as glycolic acid, thiocyanic acid, lactic acid, succinic acid, citric acid, benzoic acid, cinnamic acid, oxalic acid, saturated or monounsaturated or diunsaturated fatty acids having 6 to 20 carbon atoms, alkyl sulfate monoesters, alkyl sulfonic acids (sulfonic acids having linear or branched alkyl radicals having 1 to 20 carbon atoms), aryl sulfonic acids or aryl disulfonic acids (sulfonic acids having one or two aryl groups). Examples of suitable phosphonic acids include the following: aromatic phenyl and naphthyl radicals having a sulfonic acid group), alkylphosphonic acids (phosphonic acids having a straight or branched alkyl radical having 1 to 20 carbon atoms), arylphosphonic acids or aryldiphosphonic acids (aromatic radicals such as phenyl and naphthyl having one or two phosphonic acid groups), said alkyl and said aryl radicals may carry further substituents, for example p-toluenesulfonic acid, salicylic acid, p-aminosalicylic acid, 2-phenoxybenzoic acid, 2-acetobenzoic acid.

[0054] Solvates of the compounds or their salts present in the compound combinations of the invention are stoichiometric compositions of the compound with a solvent.

[0055] The N-oxides of the compounds present in the compound combinations of the present invention or of their intermediates can be obtained in a simple manner by customary methods, for example by N-oxidation with hydrogen peroxide (HO), peracids, for example peroxysulfuric acid or peroxycarboxylic acids such as metachloroperoxybenzoic acid or peroxymonosulfuric acid (Caro's acid).

[0056] For example, the corresponding N-oxides may be prepared starting from the respective compounds by conventional oxidation methods, for example by treating the compounds with organic peroxy acids such as metachloroperbenzoic acid (e.g., WO 2003 / 64572 or J. Med. Chem. 38 (11), 1892-1903, 1995); or inorganic oxidizing agents such as hydrogen peroxide (e.g., J. Heterocyc. Chem. 18 (7), 1305-1308, 1981) or oxone (e.g., J. Am. Chem. Soc. 123 (25), 5962-5973, 2001). The oxidation may result in pure mono N-oxides or in different N-oxides, the latter of which can be separated by conventional methods such as chromatography.

[0057] Crystal morphology The compounds present in the compound combinations of the present invention may exist in multiple crystalline and / or amorphous forms. Crystalline forms include non-solvated crystalline forms, solvates and hydrates.

[0058] formulation The present invention further relates to a composition for controlling unwanted microorganisms, said composition comprising a compound combination according to the invention. The composition may be applied to the microorganisms and / or their habitat.

[0059] The compositions comprise a compound combination of the present invention and at least one agriculturally suitable adjuvant, such as a carrier and / or a surfactant.

[0060] Carriers are generally inert solid or liquid, natural or synthetic, organic or inorganic materials. Carriers generally improve the spreading of active compounds, for example, to plants, plant parts or seeds. Examples of suitable solid carriers include, but are not limited to, ammonium salts, natural rock powders such as kaolin, clay, talc, chalk, quartz, attapulgite, montmorillonite and diatomaceous earth, and synthetic rock powders such as fine silica, alumina and silicates. Examples of commonly useful solid carriers for granulation manufacturing include, but are not limited to, crushed and divided natural stones such as calcite, marble, pumice, sepiolite and dolomite, synthetic granules of inorganic and organic powders, and granules of organic materials such as paper, sawdust, coconut shell flour, corn cob and tobacco stalk. Examples of suitable liquid carriers include, but are not limited to, water, organic solvents and combinations thereof. Examples of suitable organic solvents include, for example, polar and non-polar organic chemical liquids from the classes of aromatic and non-aromatic hydrocarbons (such as cyclohexane, paraffins, alkylbenzenes, xylenes, toluene, alkylnaphthalenes, chlorinated aromatics or chlorinated aliphatic hydrocarbons, such as chlorobenzene, chloroethylene or methylene chloride), alcohols and polyols (which may be substituted, etherified and / or esterified, such as butanol or glycols), ketones (acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone), esters (including fats and oils) and (poly)ethers, unsubstituted and substituted amines, amides (such as dimethylformamide), lactams (N-alkylpyrrolidones) and lactones, sulfones and sulfoxides (such as dimethylsulfoxide). The carrier may also be a liquefied gas extender, i.e. a liquid that is a gas at standard temperature and pressure, such as, for example, an aerosol propellant, such as halohydrocarbons, butane, propane, nitrogen and carbon dioxide. The amount of the carrier is usually in the range of 1 to 99.99% by weight, preferably 5 to 99.9% by weight, more preferably 10 to 99.5% by weight, and most preferably 20 to 99% by weight of the composition.

[0061] The surfactants may be ionic (cationic or anionic) or non-ionic surfactants, such as, for example, ionic or non-ionic emulsifiers, foaming agents, dispersing agents, wetting agents and any mixtures thereof. Examples of suitable surfactants include, but are not limited to, polyacrylates, lignosulfonates, phenolsulfonates or naphthalenesulfonates, polycondensates of ethylene oxide and / or propylene oxide with aliphatic alcohols, fatty acids or fatty amines (polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, e.g., alkylaryl polyglycol ethers), substituted phenols (preferably alkylphenols or arylphenols), sulfosuccinic acid esters, taurine derivatives (preferably alkyl taurates), phosphoric acid esters of polyethoxylated alcohols or phenols, fatty esters of polyols and derivatives of compounds including sulfates, sulfonates, phosphates (e.g., alkylsulfonates, alkyl sulfates, arylsulfonates) and protein hydrolysates, lignosulfite waste liquors and methylcellulose. Surfactants are usually used when the compounds and / or carriers of the compound combination of the present invention are water-insoluble and spraying is carried out with water. When present, the amount of surfactant will typically range from 5 to 40% by weight based on the total weight of the composition.

[0062] Further examples of suitable auxiliaries include water repellents, drying agents, binders (adhesives, tackifiers, fixatives, such as, for example, carboxymethylcellulose, natural and synthetic polymers in the form of powders, granules or latexes, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, natural and synthetic phospholipids, such as cephalin and lecithin, polyvinylpyrrolidone and tylose), thickeners, stabilizers (for example, cold stabilizers, preservatives, antioxidants, light stabilizers or other agents which improve chemical and / or physical stability), dyes or pigments (inorganic pigments, such as, for example, iron oxide, titanium oxide and Prussian blue). roux; organic dyes, such as alizarin, azo and metal phthalocyanine dyes, defoamers (such as silicone defoamers and magnesium stearate), preservatives (such as dichlorophen and benzyl alcohol hemiformal), secondary thickeners (cellulose derivatives, acrylic acid derivatives, xanthan, modified clays and finely divided silica), fixing agents, gibberellins and processing aids, mineral and vegetable oils, fragrances, waxes, nutrients (such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc, including micronutrients), protective colloids, thixotropic substances, penetrating agents, sequestering agents and complexing agents.

[0063] The choice of auxiliary agent is related to the desired method of application and / or physical properties of the compound combination of the present invention.Furthermore, auxiliary agents may be selected to impart specific properties (technical, physical and / or biological properties) to the formulation / composition or to use the form produced therefrom.The choice of auxiliary agent may allow the composition to be customized to specific needs.

[0064] The compositions may be in any conventional form, such as liquids (e.g., aqueous liquids), emulsifiable concentrates, wettable powders, water- and oil-based suspensions, dusts, powders, pastes, water-soluble, soluble granules, granules for general application, suspoemulsion concentrates, natural or synthetic products impregnated with the compound combination of the present invention, microencapsulation of fertilizers and polymeric materials, etc. The compound combination of the present invention may be present in suspended, emulsified or dissolved form.

[0065] The abovementioned formulations can be prepared in a manner known per se, for example by mixing the active ingredient with at least one auxiliary agent.

[0066] The compositions may be provided to the end user as a ready-to-use formulation, i.e., the composition may be applied directly to the plants or seeds by suitable equipment such as a sprayer or duster, or alternatively, the compositions may be provided to the end user in the form of a concentrated formulation that must be diluted, preferably with water, before use.

[0067] The formulations generally contain 0.01-99% by weight, 0.05-98% by weight, preferably 0.1-95% by weight, more preferably 0.5-90% by weight, and most preferably 1-80% by weight of the compound combination of the present invention. When the composition comprises two or more active ingredients, the outlined ranges represent the total amount of the compound combination of the present invention.

[0068] The formulations can be used to control undesirable microorganisms by applying them to the microorganisms and / or their habitat.

[0069] In one particular embodiment of the present invention, the compound combination is provided in a sprayable form that allows for spray application. In this embodiment, the compound combination according to the present invention is provided as a composition / formulation comprising the active ingredient and at least one suitable liquid carrier.

[0070] Suitable liquid carriers are preferably selected from water, organic solvents and combinations thereof. More preferably, the liquid carrier is water or a mixture of water and an organic solvent.

[0071] Preferred suitable organic solvents are those already mentioned above.

[0072] The amount of the liquid carrier will usually be in the range of 1 to 99.99% by weight, preferably 5 to 99.9% by weight, more preferably 10 to 99.5% by weight, and most preferably 20 to 99% by weight of the composition.

[0073] Preferably, the sprayable composition further comprises at least one surfactant. Suitable surfactants are disclosed above. It may also comprise at least one further auxiliary agent as outlined above.

[0074] Preferably, the sprayable composition is provided as an emulsifiable concentrate or suspension concentrate, more preferably as an emulsifiable concentrate comprising the active ingredient in a total amount of 20 to 400 g / L, preferably 40 to 200 g / L, or as a suspension concentrate comprising the active ingredient in a total amount of 50 to 500 g / L, preferably 100 to 400 g / L.

[0075] The preparation of said concentrates is well known to those skilled in the art. For example, emulsifiable concentrates (EC) can be prepared by dissolving the desired amount of active ingredient, e.g., a 20-400 g / liter concentrate, and at least one surfactant, e.g., a 50-100 g / liter concentrate, in a water-insoluble organic solvent, e.g., an aromatic hydrocarbon, or a water-soluble organic solvent, e.g., N-methyl-2-pyrrolidone (NMP), dimethyl sulfoxide (DMSO), γ-butyrolactone. Suspension concentrates (SC) can be prepared by mixing the desired amount of active ingredient, e.g., a 50-500 g / liter concentrate, at least one surfactant, e.g., a 20-100 g / liter concentrate, and at least one binder and / or secondary thickener, e.g., a 1-20 g / liter concentrate, and suspending the mixture in water.

[0076] Preferably, the concentrate is diluted with water before it is sprayed on plants or parts thereof. More preferably, the emulsifiable concentrate or suspension concentrate is mixed with water in an amount such that a total concentration of active ingredient in the resulting mixture is between 0.1 and 5, preferably between 0.2 and 2, more preferably between 0.25 and 1 g / l.

[0077] Further active ingredients The compound combinations according to the invention can be used as such or in compositions / formulations thereof or can be mixed with further known active ingredients, e.g. antibacterials, acaricides, nematicides or insecticides, for example in order to broaden the activity spectrum or to prevent resistance development in this way.

[0078] Useful mixing partners include, for example, insecticides, acaricides, nematicides and antimicrobial agents (see also Pesticide Manual, 14th ed.).

[0079] Mixtures with other known active ingredients, such as herbicides, or fertilizers and growth regulators, safeners and / or semiochemicals are also possible.

[0080] The terms "insecticide" and "insecticidal" refer to the ability of a substance to increase mortality or inhibit the growth rate of insects. As used herein, the term "insects" comprises all organisms in the class "Insecta".

[0081] "Nematicide" and "nematicidal" refer to the ability of a substance to increase mortality or inhibit the growth rate of nematodes. In general, the term "nematodes" comprises eggs, larvae, juveniles and adult forms of said organisms.

[0082] "Acaricide" and "acaricidal" refer to the ability of a substance to increase mortality or inhibit the growth rate of ectoinfestations of the class Arachnida, subclass Acarina.

[0083] Examples of insecticides, acaricides and nematicides, respectively, which can be mixed with the compound combinations of the present invention are as follows: (1) Acetylcholinesterase (AChE) inhibitors, preferably carbamates selected from alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb, XMC and xylylcarb; or acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, cadusafos, chlorethoxyphos, chlorfenvinphos, chlormephos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos / DDVP, dicrotophos, dimethoate an organic phosphate selected from among phosphate, dimethylvinphos, disulfoton, EPN, ethion, ethoprophos, famfur, fenamiphos, fenitrothion, fenthion, fosthiazate, heptenophos, imicyaphos, isofenphos, isopropyl O-(methoxyaminothiophosphoryl)salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton methyl, parathion methyl, phenthoate, phorate, phosalone, phosmet, phosphamidon, phoxim, pirimiphos methyl, profenofos, propetamphos, prothiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimphos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon and vamidothion.

[0084] (2) GABA-gated chloride channel blockers, preferably cyclodiene-organochlorines selected from chlordane and endosulfan, or phenylpyrazoles (fiproles) selected from ethiprole and fipronil.

[0085] (3) Sodium channel modulators, preferably acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, bioallethrin, bioallethrin s-cyclopentenyl isomer, bioresmethrin, cycloprothrin, cyfluthrin, β-cyhalothrin, cyhalothrin, λ-cyhalothrin, γ-cyhalothrin, cypermethrin, α-cypermethrin, β-cypermethrin, θ-cypermethrin, zeta-cypermethrin, cyphenothrin [(1R)-trans isomer], deltamethrin, empenthrin [(EZ)-( pyrethroids selected from: esfenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, taufluvalinate, halfenprox, imiprothrin, kadesrin, momfluorothrin, permethrin, fenothrin [(1R)-trans isomer], prallethrin, pyrethrins (pyrethrum), resmethrin, silafluofen, tefluthrin, tetramethrin, tetramethrin [(1R)-isomer)], tralomethrin and transfluthrin or DDT or methoxychlor.

[0086] (4) Nicotinic acetylcholine receptor (nAChR) competitive modulators, preferably neonicotinoids selected from acetamide, clothianidin, dinotefuran, imidacloprid, nithembiram, thiacloprid and thiamethoxam, or nicotine, or sulfoximines selected from sulfoxaflor, or butenolides selected from flupyradifurone, or mesoions selected from triflumezopyrim.

[0087] (5) Nicotinic acetylcholine receptor (nAChR) allosteric modulators (site I), preferably spinosyns selected from spinetoram and spinosad.

[0088] (6) Glutamate-gated chloride channel (GluCl) allosteric modulators, preferably avermectins / mibemycins selected from abamectin, emamectin benzoate, lepimectin and milbemectin.

[0089] (7) Juvenile hormone mimetics, preferably juvenile hormone analogs selected from hydroprene, kinoprene and methoprene or fenoxycarb or pyriproxyfen.

[0090] (8) Various non-specific (multipoint) inhibitors, preferably alkyl halides selected from methyl bromide and other alkyl halides; or methyl isocyanate generating agents selected from chloropicrin or sulfuryl fluoride or borax or tartar emetic or dazomet and metam.

[0091] (9) Chordotonal TRPV channel modulators, preferably pyridineazomethanes selected from pymetrozine and pyrifluquinazone, or pyropenes selected from afidopyropene.

[0092] (10) A mite growth inhibitor acting on CHS1 selected from clofentezine, hexythiazox, diflovidazine and etoxazole.

[0093] (11) A microbial disruptor of an insect gut membrane selected from Bacillus thuringiensis subsp. israelensis, Bacillus sphaericus, Bacillus thuringiensis subsp. aizawai, Bacillus thuringiensis subsp. kurstaki, and Bacillus thuringiensis subsp. tenebrionis, and a Bt plant protein selected from Cry1Ab, Cry1Ac, Cry1Fa, Cry1A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, and Cry34Ab1 / 35Ab1.

[0094] (12) Inhibitors of mitochondrial ATP synthase, preferably ATP disruptors selected from diafenthiuron, or organotin compounds selected from azocyclotin, cyhexatin and fenbutatin oxide, or propargite or tetradifon.

[0095] (13) Uncouplers of oxidative phosphorylation by disruption of the proton gradient selected from chlorfenapyr, DNOC, and sulfluramide.

[0096] (14) A nicotinic acetylcholine receptor channel blocker selected from bensultap, cartap hydrochloride, thiosultap sodium salt.

[0097] (15) Inhibitors of chitin biosynthesis acting on CHS1, preferably benzoylureas selected from bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron and triflumuron.

[0098] (16) An inhibitor of chitin biosynthesis selected from buprofezin, type 1.

[0099] (17) A molting disruptor selected from cyromazine (especially for Diptera, i.e., for insects of the order Diptera).

[0100] (18) An ecdysone receptor agonist preferably selected from chromafenozide, halofenozide, methoxyfenozide and tebufenozide.

[0101] (19) An octopamine receptor agonist selected from amitraz.

[0102] (20) A mitochondrial electron transport chain complex III inhibitor selected from hydramethylnon, acequinocyl, fluacrypyrim and bifenazate.

[0103] (21) Mitochondrial electron transport chain complex I inhibitors, preferably METI acaricides and insecticides selected from fenazaquin, fenpyroximate, pyrimidifen, pirdaben, tebufenpyrad and tolfenpyrad, or rotenone (Derris).

[0104] (22) Voltage-dependent sodium channel inhibitors, preferably oxadiazines selected from indoxacarb, or semicarbazones selected from metaflumizone.

[0105] (23) Inhibitors of acetyl-CoA carboxylase, preferably tetronic and tetramic acid derivatives selected from spirodiclofen, spiromesifen, spiropydione and spirotetramate.

[0106] (24) Mitochondrial electron transport chain complex IV inhibitors, preferably phosphines selected from aluminum phosphide, calcium phosphide, phosphorus hydride and zinc phosphide, or cyanides selected from calcium cyanide, potassium cyanide and sodium cyanide.

[0107] (25) Mitochondrial electron transport complex II inhibitors, preferably β-ketonitrile derivatives selected from cyenopyrafen and cyflumetofen, or carboxanilides selected from piflubumid.

[0108] (26) Ryanodine receptor modulators, preferably diamides selected from chlorantraniliprole, cyantraniliprole, flubendiamide and tetraniliprole.

[0109] (27) Chordotonal organ modulators selected from flonicamide (with unclear target site).

[0110] (28) GABA-gated chloride ion channel allosteric modulators, preferably meta-diamides selected from broflanilide, or isoxazoles selected from fluxamethamide.

[0111] (29) A baculovirus, preferably a granulovirus (GV) selected from Cydia pomonella GV and Thaumatotibia leucotreta (GV), or a nuclear polyhedrosis virus (NPV) selected from Anticarsia gemmatalis MNPV, flucipiriprole and Helicoverpa armigera NPV.

[0112] (30) Nicotinic acetylcholine receptor allosteric modulators (site II) selected from GS-ω / κHXTX-Hv1a peptides.

[0113] (31) Acinonapyr, afoxolaner, azadirachtin, benclotiaz, benzoximate, benzpyrimoxane, bromopropylate, quinomethionate, chlorprallethrin, cryolite, cyclobutrifluram, cycloxapride, sietopyrafen, cyhalodiamide, cyprofuranilide (CAS 2375110-88-4), chlormezothiaz, dicofol, dinpropylidaz, epsilon-metofluthrin, epsilon-momfluthrin, flometoquin, fluazaindolizine, flucipiriprole (CAS 2375110-88-4) 1771741-86-6), fluensulfone, flufenerim, flufenoxystrobin, flufiprole, fluhexafon, fluopyram, flupirimine, fluralaner, flufenozide, flupentiofenox, guadipyr, heptafluthrin, imidaclothiz, iprodione, isocycloceram, kappa-bifenthrin, kappa-tefluthrin, lotilaner, meperfluthrin, nicofluprole (CAS 1771741-86-6), oxazosulfil, paichondine, pyridalyl, pyrifluquinazon, pyriminostrobin, sarolaner, spidoxamate, spirodiclofen, tetramethylfluthrin, tetrachlorantraniliprole, tigoranel, thioxazafen, thiofluoximate, cyclopyrazoflor, iodomethane; Bacillus pharmaceuticals (Bacillus Further active compounds selected from further formulations based on I. firmus (I-1582, Votivo) and azadirachtin (BioNeem), further compounds: 1-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}-3-(trifluoromethyl)-1H-1,2,4-triazol-5-amine (known from WO 2006 / 043635) (CAS 885026-50-6), 2-chloro-N-[2-{1-[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl]piperidin-4-yl}-4-(trifluoromethyl)phenyl]isonicotinamide (known from WO 2006 / 003494) (CAS 872999-66-1), 3-(4-chloro-2,6-dimethylphenyl)-4-hydroxy-8-methoxy-1,8-Diazaspiro[4.5]dec-3-en-2-one (known from WO 2010 / 052161) (CAS 1225292-17-0), ethyl 3-(4-chloro-2,6-dimethylphenyl)-8-methoxy-2-oxo-1,8-diazaspiro[4.5]dec-3-en-4-yl carbonate (known from European Patent Application Publication No. 2647626) (CAS 1440516-42-6), PF1364 (known from JP 2010-018586) (CAS 1204776-60-2), (3E)-3-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-1,1,1-trifluoro-propan-2-one (known from WO 2013 / 144213) (CAS 1461743-15-6), N-[3-(benzylcarbamoyl)-4-chlorophenyl]-1-methyl-3-(pentafluoroethyl)-4-(trifluoromethyl)-1H-pyrazole-5-carboxamide (known from WO 2010 / 051926) (CAS 1226889-14-0), 5-bromo-4-chloro-N-[4-chloro-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloro-2-pyridyl)pyrazole-3-carboxamide (known from Chinese Patent No. 103232431) (CAS 1449220-44-3), 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-N-(cis-1-oxido-3-thietanyl)-benzamide, 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-N-(trans-1-oxido-3-thietanyl)-benzamide amide and 4-[(5S)-5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-N-(cis-1-oxido-3-thietanyl)benzamide (known from WO 2013 / 050317(A1)) (CAS 1332628-83-7), N-[3-chloro-1-(3-pyridinyl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)sulfinyl]-propanamide, (+)-N-[3-chloro-1-(3-pyridinyl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)sulfinyl]-propanamide and (-)-N-[3-chloro-1-(3-pyridinyl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)sulfinyl]-propanamide (known from WO 2013 / 162715 (A2), WO 2013 / 162716 (A2), U.S. Patent Application Publication No. 2014 / 0213448 (A1)) (CAS 1477923-37-7), 5-[[(2E)-3-chloro-2-propen-1-yl]amino]-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile (known from China Patent Application Publication No. 101337937) (CAS 1105672-77-2), 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)thioxomethyl]phenyl]-1-(3-chloro-2 -pyridinyl)-1H-pyrazole-5-carboxamide, (Liudaibenjiaxuanan, known from China Patent Application Publication No. 103109816) (CAS 1232543-85-9); N-[4-chloro-2-[[(1,1-dimethylethyl)amino]carbonyl]-6-methylphenyl]-1-(3-chloro-2-pyridinyl)-3-(fluoromethoxy)-1H-pyrazole-5-carboxamide (known from WO 2012 / 034403(A1)) (CAS 1268277-22-0), N-[2-(5-amino-1,3,4-thiadiazol-2-yl)-4-chloro-6-methylphenyl]-3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide (known from WO 2011 / 085575(A1)) (CAS 1233882-22-8), 4-[3-[2,6-dichloro-4-[(3,3-Dichloro-2-propen-1-yl)oxy]phenoxy]propoxy]-2-methoxy-6-(trifluoromethyl)-pyrimidine (known from Chinese Patent Application Publication No. 101337940) (CAS 1108184-52-6); (2E)- and 2(Z)-2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(difluoromethoxy)phenyl]-hydrazinecarboxamide (known from Chinese Patent Application Publication No. 101715774) (CAS 1232543-85-9); 3-(2,2-dichloroethenyl)-2,2-dimethyl-4-(1H-benzimidazol-2-yl)phenyl-cyclopropanecarboxylic acid ester (known from Chinese Patent Application Publication No. 103524422) (CAS 1542271-46-4;(4aS)-7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-[(trifluoromethyl)thio]phenyl]amino]carbonyl]-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic acid methyl ester (known from China Patent Application Publication No. 102391261) (CAS 1370358-69-2);6-deoxy-3-O-ethyl-2,4-di-O-methyl-,1-[N-[4-[1-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-1H-1,2,4-triazol-3-yl]phenyl]carbamate]-α-L-mannopyranose (known from US Patent Application Publication No. 2014 / 0275503(A1)) (CAS 1181213-14-8); 8-(2-cyclopropylmethoxy-4-trifluoromethyl-phenoxy)-3-(6-trifluoromethyl-pyridazin-3-yl)-3-aza-bicyclo[3.2.1]octane (CAS 1253850-56-4), (8-anti)-8-(2-cyclopropylmethoxy-4-trifluoromethyl-phenoxy)-3-(6-trifluoromethyl-pyridazin-3-yl)-3-aza-bicyclo[3.2.1]octane (CAS 933798-27-7), (8-syn)-8-(2-cyclopropylmethoxy-4-trifluoromethyl-phenoxy)-3-(6-trifluoromethyl-pyridazin-3-yl)-3-aza-bicyclo[3.2.1]octane (known from WO 2007 / 040280(A1) and WO 2007 / 040282(A1)) (CAS 934001-66-8), N-[4-(aminothioxomethyl)-2-methyl-6-[(methylamino)carbonyl]phenyl]-3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide (known from China Patent Application Publication No. 103265527) (CAS 1452877-50-7), 3-(4-chloro-2,6-dimethylphenyl)-8-methoxy-1-methyl-1,8-diazaspiro[4.5]decane-2,4-dione (known from WO 2014 / 187846(A1)) (CAS 1638765-58-8), 3-(4-chloro-2,6-dimethylphenyl)-8-methoxy-1-methyl-2-oxo-1,8-diazaspiro[4.5]dec-3-en-4-yl-carbonic acid ethyl ester (known from WO 2010 / 066780(A1), WO 2011151146(A1)) (CAS 1229023-00-0), N-[1-[(2,6-difluorophenyl)-1H-pyrazol-3-yl]-2-(trifluoromethyl)benzamide (known from WO 2014 / 053450(A1)) (CAS 1594624-87-9), N-[(2,6-difluorophenyl)-2H-1,2,3-triazol-4-yl]-2-(trifluoromethyl)benzamide (known from WO 2014 / 053450(A1)) (CAS 1594637-65-6), N-[1-(3,5-difluoro-2-pyridinyl)-1H-pyrazol-3-yl]-2-(trifluoromethyl)benzamide (known from WO 2014 / 053450(A1)) (CAS 1594626-19-3), (3R)-3-(2-chloro-5-thiazolyl)-2,3-dihydro-8-methyl-5,7-dioxo-6-phenyl-5H-thiazolo[3,2-a]pyrimidinium inner salt (known from WO 2018 / 177970(A1)) (CAS 2246757-58-2; 3-(2-chloro-5-thiazolyl)-2,3-dihydro-8-methyl-5,7-dioxo-6-phenyl-5H-thiazolo[3,2-a]pyrimidinium inner salt (known from WO 2018 / 177970(A1)) (CAS 2246757-56-0); N-[3-chloro-1-(3-pyridinyl)-1H-pyrazol-4-yl]-2-(methylsulfonyl)-propanamide (known from WO 2019 / 236274(A1)) (CAS 2396747-83-2), N-[2-bromo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]-2-fluoro-3-[(4-fluorobenzoyl)amino]-benzamide (known from WO 2019 / 059412(A1)) (CAS 1207977-87-4), 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4,6-dichloro-3-fluoro-2-[(methylamino)carbonyl]phenyl]-1H-pyrazole-5-carboxamide (fluchlorodiamide; Chinese patent no. (CAS: 2129147-03-9).

[0114] Examples of nematicides which may be mixed with the compound combinations and compositions of the present invention are: (Group N-1) Acetylcholinesterase (AChE) inhibitors, preferably (N-1A) carbamates selected from alanycarb, benfuracarb, carbofuran, carbosulfan and thiodicarb, or (N-1B) organic phosphates selected from cadusafos, ethoprophos, fenamiphos, fosthiazate, imicyaphos, phorate and terbufos; (Group N-2) GluCl-gated chloride channel (GluCl) allosteric modulators, preferably avermectins selected from abamectin and emamectin benzoate; (Group N-3) Mitochondrial electron transport complex II inhibitors, in particular, succinic coenzyme Q reductase inhibitors, preferably pyridinylmethyl-benzamides selected from fluopyram; (Group N-4) Lipid synthesis / growth regulation modulators, in particular inhibitors of acetyl-CoA carboxylase, preferably tetronic and tetramic acid derivatives selected from spirotetramats; (Groups N-UN) Compounds with unknown or uncertain modes of action that interact with various chemicals selected from fluensulfone, fluazaindolizine, furfural, iprodione and thioxazaphene; (Groups N-UNX) Compounds of unknown or uncertain mode of action: putative multi-point inhibitors, preferably volatile sulfur generators selected from carbon disulfide and dimethyl disulfide (DMDS), or carbon disulfide liberators selected from sodium tetrathiocarbonate, or alkyl halides selected from methyl bromide and methyl iodide (iodomethane), or halogenated hydrocarbons selected from 1,2-dibromo-3-chloropropane (DBCP) and 1,3-dichloropropene, or methyl isothiocyanate generators selected from allyl isothiocyanate, diazomet, metam potassium and metam sodium; (Group N-UNB) Bacterial agents of unknown or uncertain mode of action (non-Bt), preferably Burkholderia spp., such as rinojensis A396, Bacillus spp., such as firmus, licheniformis, amyloliquefaciens or subtilis, Pasteuria spp., such as penetrans or nishizawae, Pseudomonas spp., such as chlororaphis or fluorescens, and Streptomyces spp. spp.), for example a bacterium or a bacterium-derived bacterium selected from lydicus, dicklowii or albogriseolus, (Group N-UNF) Fungal agents with unknown or uncertain mode of action, preferably Actinomyces spp., for example, streptococcus, Arthrobotrys spp., for example, oligospora, Aspergillus spp., for example, niger, Muscodor spp., for example, verrucaria, Paecilomyces spp., for example, lilacinus (Purpureocillium lilacinum), carneus or fumosoroseus, Pochonia chlamydosporia. fungi or fungal-derived fungi selected from the genera Chlamydosporia, and Trichoderma spp., for example Harzianum, Virens, Atroviride or Viride; (Group N-UNE) Plant or animal derived drugs including synthetic extracts and unrefined oils with unknown or uncertain mode of action, preferably plant or animal derived drugs selected from azadirachtin, camellia seed cake, essential oils, garlic extract, pongamia oil, terpenes such as carvacrol, and Quillaja saponaria extract; It is.

[0115] Examples of herbicides which may be mixed with the compound combination of the present invention are: Acetochlor, Acifluorfen, Acifluorfen-methyl, Acifluorfen-sodium, Aclonifen, Alachlor, Allidochlor, Alloxydim, Alloxydim-sodium, Ametryn, Amicarbazone, Amidochlor, Amidosulfuron, 4-Amino-3-chloro-6-(4-chloro-2-fluoro-3-methylphenyl)-5-fluoropyridine-2-carboxylic acid, Aminocyclopyrachlor, Aminocyclopyrachlor-potassium, Aminocyclopyrachlor-methyl, Aminopyralid, Aminopyralid-dimethylammoni Aminopyralid-trypromine, Amitrole, Ammonium sulfamate, Anilofos, Asulam, Asulam-potassium, Asulam-sodium, Atrazine, Azafenidine, Azimsulfuron, Beflubutamid, (S)-(-)-Beflubutamid, Beflubutamid-M, Benazolin, Benazolin-ethyl, Benazolin-dimethylammonium, Benazolin-potassium, Benfluralin, Benfuresate, Bensulfuron, Bensulfuron-methyl, Bensulide, Bentazon, Bentazon-sodium, Benzobicyclon, Benzophenone Nap, bicyclopyrone, bifenox, bilanaphos, bilanaphos-sodium, bipyrazone, bispyribac, bispyribac-sodium, bixlozone, bromacil, bromacil-lithium, bromacil-sodium, bromobutide, bromofenoxime, bromoxynil, bromoxynil-butyrate, potassium, heptanoate, and octanoate, busoxynone, butachlor, butafenacil, butamifos, butenachlor, butralin, butroxydim, butyrate, cafenstrole, cambenziclor, carbetamide , carfentrazone, carfentrazone-ethyl, chloramben, chloramben-ammonium, chloramben-diolamine, chloramben-methyl, chloramben-methylammonium, chloramben-sodium, chlorbromuron, chlorfenac, chlorfenac-ammonium, chlorfenac-sodium, chlorfenprop, chlorfenprop-methyl, chlorflurenol, chlorflurenol-methyl, chloridazon, chlorimuron, chlorimuron-ethyl, chlorphthalim, chlorotoluron, chlorsulfuron,Chlorthal, chlorthal-dimethyl, chlorthal-monomethyl, cinidon, cinidon-ethyl, cinmethylin, exo-(+)-cinmethylin, i.e., (1R,2S,4S)-4-isopropyl-1-methyl-2-[(2-methoxybenzyl)oxy]-7-oxabicyclo[2.2.1]heptane, exo-(-)-cinmethylin, i.e., (1R,2S,4S)-4-isopropyl-1-methyl-2-[(2-methoxybenzyl)oxy]-7-oxabicyclo[2.2.1]heptane, cinosulfuron, clasifos, clethodim, closulfuron, clasifos, clethodim, Dinafop, clodinafop-ethyl, clodinafop-propargyl, clomazone, clomeprop, clopyralid, clopyralid-methyl, clopyralid-olamine, clopyralid-potassium, clopyralid-trypomine, cloransulam, cloransulam-methyl, cumyluron, cyanamide, cyanazine, cycloate, cyclopyranyl, cyclopyrimorate, cyclosulfamuron, cycloxydim, cyhalofop, cyhalofop-butyl, cyprazine, 2,4-D (ammonium, -butyric acid, -butyl, choline, dimethylammonium, - ... Dimethylammonium, -diolamine, -doboxyl, -dodecylammonium, ethyxyl, ethyl, 2-ethylhexyl, heptylammonium, isobutyl, isooctyl, isopropyl, isopropylammonium, lithium, meptyl, methyl, potassium, tetradecylammonium, triethylammonium, triisopropanolammonium, tryptophan and tetraolamine salts), 2,4-DB, 2,4-DB-butyl, dimethylammonium, isooctyl, potassium and sodium, dymron (dymron), dara ... Pon, dalapon-calcium, dalapon-magnesium, dalapon-sodium, dazomet, dazomet-sodium, n-decanol, 7-deoxy-D-sedoheptulose, desmedipham, destosyl-pyrazolate (DTP), dicamba and its salts, such as dicamba-biproamine, dicamba-N,N-bis(3-aminopropyl)methylamine, dicamba-butotyl, dicamba-choline, dicamba-diglycolamine, dicamba-dimethylammonium, dicamba-diethanolamine ammonium, dicamba-diethylammonium,Dicamba-isopropylammonium, Dicamba-methyl, Dicamba-monoethanolamine, Dicamba-olamine, Dicamba-potassium, Dicamba-sodium, Dicamba-triethanolamine, Dicamba-triethanolamine, Dichlobenil, 2-(2,4-dichlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one, 2-(2,5-dichlorobenzyl)-4,4-dimethyl-1,2-oxazolidin-3-one, Dichlorprop, Dichlorprop-butotyl, Dichlorprop-dimethylammonium, Dichlorprop-ethoxy sil, dichlorprop-ethylammonium, dichlorprop-isooctyl, dichlorprop-methyl, dichlorprop-potassium, dichlorprop-sodium, dichlorprop-P, dichlorprop-P-dimethylammonium, dichlorprop-P-ethexyl, dichlorprop-P-potassium, dichlorprop-sodium, diclofop, diclofop-methyl, diclofop-P, diclofop-P-methyl, diclosulam, difenzoquat, difenzoquat-methyl sulfate, difenzoquat Lufenican, Diflufenzopyr, Diflufenzopyr-Sodium, Dimefuron, Dimepiperate, Dimethasulfazate, Dimethachlor, Dimethamethrin, Dimethenamid, Dimethenamid-P, Dimetrasulfuron, Dinitramine, Dinoterb, Dinoterb-Acetate, Diphenamide, Diquat, Diquat-Dibromide, Diquat-Dichloride, Dithiopyr, Diuron, DNOC, DNOC-Ammonium, DNOC-Potassium, DNOC-Sodium, Endothal, Endothal-Diammonium, Endothal -dipotassium, endothal-disodium, epirifenacil (S-3100), EPTC, esprocarb, ethalfluralin, ethametsulfuron, ethametsulfuron-methyl, ethiozin, ethofumesate, ethoxyphene, ethoxyphene-ethyl, ethoxysulfuron, etobenzanide, F-5231, i.e., N-{2-chloro-4-fluoro-5-[4-(3-fluoropropyl)-4,5-dihydro-5-oxo-1H-tetrazol-1-yl]phenyl}ethanesulfonamide, F-7967, i.e.,3-[7-chloro-5-fluoro-2-(trifluoromethyl)-1H-benzimidazol-4-yl]-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione, fenoxaprop, fenoxaprop-P, fenoxaprop-ethyl, fenoxaprop-P-ethyl, fenoxasulfone, fenpyrazone, fenquinotrione, fentrazamide, flamprop, flamprop-isopropyl, flamprop-methyl, flamprop-M-isopropyl, flamprop-M-methyl, furaza Sulfuron, Florasulam, Florpyrauxifen, Florpyrauxifen-benzyl, Fluazifop, Fluazifop-butyl, Fluazifop-methyl, Fluazifop-P, Fluazifop-P-butyl, Flucarbazone, Flucarbazone-sodium, Flucetosulfuron, Fluchloralin, Flufenacet, Flufenpyr, Flufenpyr-ethyl, Flumetsulam, Flumicrac, Flumicrac-pentyl, Flumioxazin, Fluometuron, Flurenol, Flurenol-butyl, -dimethylammonium and -methylammonium. Fluoroglycofen, Fluoroglycofen-ethyl, Flupropanate, Flupropanate-sodium, Flupyrsulfuron, Flupyrsulfuron-methyl, Flupyrsulfuron-methyl-sodium, Fluridone, Flurochloridone, Fluroxypyr, Fluroxypyr-butomethyl, Fluroxypyr-meptyl, Flurtamone, Fluthiacet, Fluthiacet-methyl, Fomesafen, Fomesafen-sodium, Foramsulfuron, Foramsulfuron-sodium salt, Fosamin, Fosamin-ammonium, Glufosinate, Glufosinate Glufosinate-ammonium, glufosinate-sodium, L-glufosinate-ammonium, L-glufosinate-sodium, glufosinate-P-sodium, glufosinate-P-ammonium, glyphosate, glyphosate-ammonium, -isopropylammonium, -diammonium, -dimethylammonium, -potassium, -sodium, sesquisodium and trimesium, H-9201, i.e., O-(2,4-dimethyl-6-nitrophenyl)-O-ethyl-isopropylphosphoramidothioate, halaxifen,Haloxifene-methyl, halosafen, halosulfuron, halosulfuron-methyl, haloxyfop, haloxyfop-P, haloxyfop-ethoxyethyl, haloxyfop-P-ethoxyethyl, haloxyfop-methyl, haloxyfop-P-methyl, haloxyfop-sodium, hexazinone, HNPC-A8169, i.e., (2S)-2-{3-[(5-tert-butylpyridin-2-yl)oxy]phenoxypropanoate prop-2-yn-1-yl, HW-02, i.e., 1-(dimethoxyphosphoryl)-ethyl-(2 ,4-Dichlorophenoxy)acetate, Hydantocidin, Imazamethabenz, Imazamethabenz-methyl, Imazamox, Imazamox-ammonium, Imazapic, Imazapic-ammonium, Imazapyr, Imazapyr-isopropylammonium, Imazaquin, Imazaquin-ammonium, Imazaquin-methyl, Imazethapyr, Imazethapyr-immonium, Imazosulfuron, Indanofan, Indaziflam, Iodosulfuron, Iodosulfuron-methyl, Iodosulfuron-methyl-sodium, Ioxynil, Ioxy nyl-lithium, -octanoate, -potassium and -sodium, ipfencarbazone, isoproturon, isouron, isoxaben, isoxaflutole, carbutilate, KUH-043, i.e., 3-({[5-(difluoromethyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl}sulfonyl)-5,5-dimethyl-4,5-dihydro-1,2-oxazole, ketospiradox, ketospiradox-potassium, lactofen, lancotrione, lenacil, linuron, MCPA, -Butotyl, -Butyl, -Dimethylammonium, -Diolamine, -2-Ethylhexyl, -Ethyl, -Isobutyl, -Isopropyl, -Isopropylammonium, -Methyl, -Olamine, -Potassium, -Sodium and -Trolamine, MCPB, MCPB-Methyl, -Ethyl and -Sodium, Mecoprop, Mecoprop-Butotyl, Mecoprop-Dimethylammonium, Mecoprop-Diolamine, Mecoprop-Ethexyl, Mecoprop-Ethadyl, Mecoprop-Isooctyl, Mecoprop-Methyl, Mecoprop-Potassium,Mecoprop-sodium, and mecoprop-trolamine, mecoprop-P, mecoprop-P-butotyl, -dimethylammonium, -2-ethylhexyl, and -potassium, mefenacet, mefluidide, mefluidide-diolamine, mefluidide-potassium, mesosulfuron, mesosulfuron-methyl, mesosulfuron sodium salt, mesotrione, methabenzthiazuron, metam, metamifop, metamitron, Metazachlor, metazosulfuron, methabenzthiazuron, methiopyrsulfuron, methiozolin, methyl isothiocyanate, metobromuron, metolachlor, S-metolachlor, metoslam, methoxuron, metribuzin, metsulfuron, metsulfuron-methyl, molinate, monolinuron, monosulfuron, monosulfuron-methyl, MT-5950, i.e., N-[3-chloro-4-(1-methylethyl)-phenyl]-2-methylpentanamide, NGGC-011, napropamide, NC-310, i.e., 4-(2,4 -dichlorobenzoyl)-1-methyl-5-benzyloxypyrazole, NC-656, i.e., 3-[(isopropylsulfonyl)methyl]-N-(5-methyl-1,3,4-oxadiazol-2-yl)-5-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridine-8-carboxamide, nebulon, nicosulfuron, nonanoic acid (pelargonic acid), norflurazon, oleic acid (fatty acid), orbencarb, orthosulfamuron, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefo oxyfluorfen, paraquat, paraquat-dichloride, paraquat-dimethylsulfate, pebulate, pendimethalin, penoxsulam, pentachlorphenol, pentoxazone, petoxamide, petroleum, phenmedipham, phenmedipham-ethyl, picloram, picloram-dimethylammonium, picloram-ethexyl, picloram-isooctyl, picloram-methyl, picloram-olamine, picloram-potassium, picloram-triethylammonium, picloram-tryplomine, picloram-trolamine, Picolinafen, pinoxaden, piperophos, pretilachlor, primisulfuron, primisulfuron-methyl, prodiamine, profoxydim, prometon, prometryn, propachlor, propanil, propaquizafop, propazine, propham, propisochlor, propoxycarbazone, propoxycarbazone-sodium, propyrisulfuron, propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraflufen, pyraflufen-ethyl, pyrasulfotole, pyrazolinate (pyrazolate), pyrazosulfuron,Pyrazosulfuron-ethyl, Pyrazoxyfen, Pyrivambenz, Pyrivambenz-isopropyl, Pyrivambenz-propyl, Pyribenzoxim, Pyributicarb, Pyridafol, Pyridate, Pyriftalid, Pyriminobac, Pyriminobac-methyl, Pyrimisulfan, Pyrithiobac, Pyrithiobac-sodium, Pyroxasulfone, Pyroxsulam, Quinclorac, Quinclorac-dimethylammonium, Quinclorac-methyl, Quinmelac, Quinoclamine, Quizalofop, Quizalofop-ethyl, Quizalofop-P, Quizalofop -P-ethyl, Quizalofop-P-tefuryl, QYM201, i.e., 1-{2-chloro-3-[(3-cyclopropyl-5-hydroxy-1-methyl-1H-pyrazol-4-yl)carbonyl]-6-(trifluoromethyl)phenyl}piperidin-2-one, Rimsulfuron, Saflufenacil, Sethoxydim, Siduron, Simazine, Simetryne, SL-261, Sulcotrione, Sulfentrazone, Sulfometuron, Sulfometuron-methyl, Sulfosulfuron, SYP-249, i.e., 1-ethoxy-3-methyl-1-oxobutan-2-one, 3-en-2-yl-5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate, SYP-300, i.e. 1-[7-fluoro-3-oxo-4-(prop-2-yn-1-yl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]-3-propyl-2-thiooxoimidazolidine-4,5-dione, 2,3,6-TBA, TCA (trichloroacetic acid) and its salts, e.g. TCA-ammonium, TCA-calcium, TCA-ethyl, TCA-magnesium, TCA-sodium, tebuthiuron, Tefuryltrione, tembotrione, tepraloxydim, terbacil, terbugalb, terbumeton, terbuthylazine, terbutryn, tetflupyrolimet, saxtomin, thenylchlor, thiazopyr, thiencarbazone, thiencarbazone-methyl, thifensulfuron, thifensulfuron-methyl, thiobencarb, thiaphenacyl, torpiralate, topramezone, tralkoxydim, triafamone, tri-allate, triasulfuron, triaziflam, tribenuron, tribenuron-methyl, triclopyr, triclopyr-butotyl,Triclopyr-choline, triclopyr-ethyl, triclopyr-triethylammonium, trietazine, trifloxysulfuron, trifloxysulfuron-sodium, trifludimoxazine, trifluralin, triflusulfuron, triflusulfuron-methyl, tritosulfuron, urea sulfate, vernolate, XDE-848, ZJ-0862, i.e., 3,4-dichloro-N-{2-[(4,6-dimethoxypyrimidine-2 -yl)oxy]benzyl}aniline, 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, [(3-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidine-1( 2H)-yl]phenoxy}pyridin-2-yl)oxy]ethyl acetate, 3-chloro-2-[(3-(difluoromethyl)isoxazolyl-5-yl]phenyl-5-chloropyrimidin-2-yl ether, 2-(3,4-dimethoxyphenyl)-4-[(2-hydroxy-6-oxocyclohex-1-en-1-yl)carbonyl]-6-methylpyridazin-3(2H)-one, 2-({2-[(2-methoxyethoxy)methyl] -6-Methylpyridin-3-yl}carbonyl)cyclohexane-1,3-dione, (5-hydroxy-1-methyl-1H-pyrazol-4-yl)(3,3,4-trimethyl-1,1-dioxide-2,3-dihydro-1-benzothiophen-5-yl)methanone, 1-methyl-4-[(3,3,4-trimethyl-1,1-dioxide-2,3-dihydro-1-benzothiophen-5-yl)carbonyl]-1H-pyrazol-5-yl Propane-1-sulfonate, 4-{2-chloro-3-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-4-(methylsulfonyl)benzoyl}-1-methyl-1H-pyrazol-5-yl-1,3-dimethyl-1H-pyrazole-4-carboxylate; 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate cyanomethyl,Prop-2-yn-1-yl 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate methyl, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylic acid, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate benzyl, 4-amino-3-chloro- 5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate ethyl, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1-isobutyryl-1H-indol-6-yl)pyridine-2-carboxylate methyl, 6-(1-acetyl-7-fluoro-1H-indol-6-yl)-4-amino-3-chloro-5-fluoropyridine-2-carboxylate methyl, 4-amino-3-chloro-6-[1-(2,2-dimethylpropanoyl)-7-fluoro-1H-indol-6-yl]-5-fluoropyridine -2-carboxylate, 4-amino-3-chloro-5-fluoro-6-[7-fluoro-1-(methoxyacetyl)-1H-indol-6-yl]pyridine-2-carboxylate methyl, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate sodium, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate sodium, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate sodium, 4-amino-3-chloro-5-fluoro-6-(7-fluoro-1H-indol-6-yl)pyridine-2-carboxylate sodium butyl pyridine-2-carboxylate, 4-hydroxy-1-methyl-3-[4-(trifluoromethyl)pyridin-2-yl]imidazolidin-2-one, 3-(5-tert-butyl-1,2-oxazol-3-yl)-4-hydroxy-1-methylimidazolidin-2-one, 3-[5-chloro-4-(trifluoromethyl)pyridin-2-yl]-4-hydroxy-1-methylimidazolidin-2-one, 4-hydroxy-1-methoxy-5-methyl-3-[4-(trifluoromethyl)pyridin-2-yl]imidazolidin-2-one,6-[(2-hydroxy-6-oxocyclohex-1-en-1-yl)carbonyl]-1,5-dimethyl-3-(2-methylphenyl)quinazoline-2,4(1H,3H)-dione, 3-(2,6-dimethylphenyl)-6-[(2-hydroxy-6-oxocyclohex-1-en-1-yl)carbonyl]-1-methylquinazoline-2,4(1H,3H)-dione, 2-[2-chloro-4-(methylsulfonyl)-3-(morpholin-4-ylmethyl)benzoyl]-3-hydroxycyclohex-2-en-1-one, 1-(2-carboxyethyl)-4-(pyrimidin-2-yl)pyridazin-1-ium salts (with anions such as chloride, acetate or trifluoroacetate), 1-(2-carboxyethyl)-4-(pyridazinyl)pyridazin-1-ium salts (with anions such as chloride, acetate or trifluoroacetate), 4-(pyrimidin-3-yl)pyridazin-1-ium salts (with anions such as chloride, acetate or trifluoroacetate), 4-(pyrimidin-2-yl)-1-(2-sulfoethyl)pyridazin-1-ium salts (with anions such as chloride, acetate or trifluoroacetate), 4-(pyridazin-3-yl)-1-(2-sulfoethyl)pyridazin-1-ium salts (with anions such as chloride, acetate or trifluoroacetate), 1-(2-carboxyethyl)-4-(1,3-thiazol-2-yl)pyridazin-1-ium salts (with anions such as chloride, acetate or trifluoroacetate), 1-(2-carboxyethyl)-4-(1,3-thiazol-2-yl)pyridazin-1-ium salts (with anions such as chloride, acetate or trifluoroacetate). It is.

[0116] Examples of plant growth regulators which may be mixed with the compound combinations and compositions of the present invention are: Abscisic acid and related analogues [e.g., (2Z,4E)-5-[6-ethynyl-1-hydroxy-2,6-dimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, (2Z,4E)-5-[6-ethynyl-1-hydroxy-2,6-dimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid methyl ester, (2Z,4E)-3-ethyl-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid methyl ester, (2E,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-(trifluoromethyl)penta-2,4-dienoic acid, (2E,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-(trifluoromethyl)penta-2,4-dienoic acid methyl ester, (2Z,4E)-5-(2-hydroxy-1,3-dimethyl-5-oxobicyclo[4.1.0]hept-3-en-2-yl)-3-methylpenta-2,4-dienoic acid], acibenzolar, acibenzolar-S-methyl, S-adenosylhomocysteine, allantoin, 2-aminoethoxyvinylglycine (AVG), aminooxyacetic acid and related esters [e.g., (isopropylidene)-aminooxyacetic acid-2-(methoxy)-2-oxoethyl ester, (isopropylidene)-aminooxyacetic acid-2-(hexyloxy)-2-oxoethyl ester, (cyclohexylidene)-aminooxyacetic acid-2-(isopropyloxy)-2-oxoethyl ester], e.g., German Patent No. 3335514, European Patent Application Publication No. 30287, German Patent Application Publication No. No. 2,906,507 or U.S. Pat. No. 5,123,951, 1-aminocycloprop-1-yl carboxylic acid and its derivatives, 5-aminolevulinic acid, ancymidol, 6-benzylaminopurine, bikinin, brassinolide, brassinolide-ethyl, L-canarin, catechin and catechins (e.g., (2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol), chitooligosaccharides (CO; CO differs from LCO in that it does not have the fatty acid pendant chains characteristic of LCO. CO is called N-acetylchitooligosaccharide and consists of GlcNAc residues, but is not bound to the chitin molecule [(CH. 13 No. 5) n , CAS No. 1398-61-4] and chitosan molecule [(C 11 No. 4) n, CAS No. 9012-76-4]), chitin compounds, chlormequat chloride, cloprop, cyclanilide, 3-(cycloprop-1-enyl)propionic acid, 1-[2-(4-cyano-3,5-dicyclopropylphenyl)acetamido]cyclohexanecarboxylic acid, 1-[2-(4-cyano-3-cyclopropylphenyl)acetamido]cyclohexanecarboxylic acid, daminozide, dazomet, dazomet-sodium, n-decanol, dikegluc, dikegluc-sodium, endothal, endothal-dipotassium, disodium, and mono(N,N-dimethylalkylammonium), ethephon, flumetralin, flurenol, flurenol-butyric acid , flurenol-methyl, flurprimidol, forchlorfenuron, gibberellic acid, inabenfide, indole-3-acetic acid (IAA), 4-indol-3-ylbutyric acid, isoprothiolane, probenazole, jasmonic acid or its derivatives (e.g., jasmonate methyl ester, jasmonate ethyl ester), lipochitooligosaccharides (LCOs, sometimes called symbiotic nodulation (Nod) signals (or Nod factors) or Myc factors, consist of an oligosaccharide backbone of β-1,4-linked N-acetyl-D-glucosamine (GlcNAc) residues with a condensed N-linked fatty acyl chain at the non-reducing end.As understood in the art, LCOs vary in the number of GlcNAc residues in the backbone, the length and degree of saturation of the fatty acyl chains, and the substitution of reducing or non-reducing sugar residues), linoleic acid or a derivative thereof, linolenic acid or a derivative thereof, maleic acid hydrazide, mepiquat chloride, mepiquat pentaborate, 1-methylcyclopropene, 3-methylcyclopropene, 1-ethylcyclopropene, 1-n-propylcyclopropene, 1-cyclopropenylmethanol, methoxyvinylglycine (MVG), 3'-methylabsinylglycine (AB ... cinnamic acid, 1-(4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide and related substituted tetrahydroquinolin-6-yl)methanesulfonamides, (3E,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one and related lactones as outlined in EP 2 248 421, 2-(1 -naphthyl)acetamide, 1-naphthylacetic acid, 2-naphthyloxyacetic acid, nitrophenolate mixtures, 4-oxo-4[(2-phenylethyl)amino]butyric acid, paclobutrazol, 4-phenylbutyric acid and related salts (e.g., sodium 4-phenylbutanoate, potassium 4-phenylbutanoate), phenylalanine, N-phenylphthalamic acid, prohexadione, prohexadione-calcium, putrescine, prohydrojasmone, rhizobitoxine, salicylic acid, salicylic acid methyl ester, sarcosine, cycloprop-1-yl Sodium cycloprop-2-en-1-yl acetate, sodium cycloprop-2-en-1-yl acetate, sodium 3-(cycloprop-2-en-1-yl)propanoate, sodium 3-(cycloprop-1-en-1-yl)propanoate, sidefungin, spermidine, spermine, strigolactone, tecnazene, thidiazuron, triacontanol, trinexapac, trinexapac-ethyl, tryptophan, tytodef, uniconazole, uniconazole-P, 2-fluoro-N-(3-methoxyphenyl)-9H-purin-6-amine,. It is.

[0117] Examples of drug relievers that can be mixed with the compound combinations and compositions of the present invention are, for example, benoxacor, cloquintocet (-mexyl), cyometrinil, cyprosulfamide, dichlormid, fenchlorazole (-ethyl), fenclorim, flurazole, fluxofenim, furilazole, isoxadifen (-ethyl), mefenpyr (-diethyl), naphthalic anhydride, oxabetrinil, 2-methoxy-N-({4-[(methylcarbamoyl)amino]phenyl}sulfonyl)benzamide (CAS 129531-12-0), 4-(dichloroacetyl)-1-oxa-4-azaspiro[4.5]decane (CAS 71526-07-3), 2,2,5-trimethyl-3-(dichloroacetyl)-1,3-oxazolidine (CAS 52836-31-4).

[0118] Examples of nitrification inhibitors that can be combined with the compound combinations and compositions of the present invention include 2-(3,4-dimethyl-1H-pyrazol-1-yl)succinic acid, 2-(4,5-dimethyl-1H-pyrazol-1-yl)succinic acid, 3,4-dimethylpyrazolium glycolate, 3,4-dimethylpyrazolium citrate, 3,4-dimethylpyrazolium lactate, 3,4-dimethylpyrazolium mandelate, 1,2,4-triazole, 4-chloro-3-methylpyrazole, N-((3(5)-methyl-1H-pyrazol-1-yl)methyl)acetamide, N-((3( 5)-Methyl-1H-pyrazol-1-yl)methyl)formamide, N-((3(5),4-dimethylpyrazol-1-yl)methyl)formamide, N-((4-chloro-3(5)-methyl-pyrazol-1-yl)methyl)formamide; Reaction adduct of dicyandiamide, urea and formaldehyde, Triazonyl-formaldehyde-dicyandiamide adduct, 2-cyano-1-((4-oxo-1,3,5-triazinan-1-yl)methyl)guanidine, 1-((2-cyanoguanidino)methyl)urea, 2-cyano-1-((2-cyano Guanidino)methyl)guanidine, 2-chloro-6-(trichloromethyl)-pyridine (Nitrapyrin or N-serve), dicyandiamide, 3,4-dimethylpyrazole phosphate, 4,5-dimethylpyrazole phosphate, 3,4-dimethylpyrazole, 4,5-dimethylpyrazole, ammonium thiosulfate, neem, products based on neem ingredients, linoleic acid, alpha-linolenic acid, methyl p-coumarate, methyl ferulate, methyl 3-(4-hydroxyphenyl)propionate, karanjin, brachialactone, p-benzoquinone sorghum leone, 4-amino-1,2,4-triazole hydrochloride, 1-amido-2-thiourea, 2-amino-4-chloro-6-methylpyrimidine, 2-mercapto-benzothiazole, 5-ethoxy-3-trichloromethyl-1,2,4-thiodiazole (telazol, etridiazole), 2-sulfanilamide thiazole, 3-methylpyrazole, 1,2,4-triazole thiourea, cyanamide, melamine, zeolite powder, catechol, benzoquinone, sodium tetraborate, allyl thiourea, chlorate, and zinc sulfate.

[0119] The compound combinations of the present invention may be combined with one or more pesticidally active agents.

[0120] Examples of agents with pesticidal activity include biostimulants, plant growth regulators, plant signaling molecules, growth promoters, microbial stimulating molecules, biomolecules, soil conditioners, nutrients, plant nutritional promoters, and others, such as lipochitooligosaccharides (LCOs), chitooligosaccharides (COs), chitinous compounds, flavonoids, jasmonic acid or its derivatives (e.g., jasmonates), cytokinins, auxins, gibberellins, abscisic acid, ethylene, brassinosteroids, salicylates, macronutrients and micronutrients, linoleic acid or its derivatives, linolenic acid or its derivatives, karrikins, and effective microorganisms (e.g., Rhizobium spp., BradyRhizobium spp., SinoRhizobium spp., AzoRhizobium spp., Glomus spp., and the like). spp.), Gigaspora spp., Hymenoscyphous spp., Oidiodendron spp., Laccaria spp., Pisolithus spp., Rhizopogon spp., Scleroderma spp., Rhizoctonia spp., Acinetobacter spp., Arthrobacter spp., Arthrobotrys spp., Aspergillus spp., Azospirillum spp. spp.), Bacillus spp., Burkholderia spp., Candida spp., Chryseomonas spp., Enterobacter spp., Eupenicillium spp., Exiguobacterium spp., Klebsiella spp., Kluyvera spp.), Microbacterium spp., Mucor spp., Paecilomyces spp., Paenibacillus spp., Penicillium spp., Pseudomonas spp., Serratia spp., Stenotrophomonas spp., Streptomyces spp., Streptosporangium spp., Swaminathania spp., Thiobacillus spp., Torulospora spp., Vibrio spp. spp.), Xanthobacter spp., Xanthomonas spp., etc.), and combinations thereof.

[0121] According to some embodiments, the compound combinations and compositions of the present invention may be combined with one or more biostimulants. Biostimulants may promote metabolic or physiological processes such as respiration, photosynthesis, nucleic acid uptake, ion uptake, nutrient delivery, or combinations thereof. Non-limiting examples of biostimulants that may be included or used in the compositions of the present invention include seaweed extracts (e.g., Ascophyllum nodosum; BAYFOLAN ALGAE, Aglukon GmbH, Germany), bacterial extracts (e.g., extracts of one or more diazotrophs, phosphate-solubilized microorgafjaponisms and / or biopesticides), fungal extracts, humic acids (e.g., potassium humate), fulvic acids, myoinositol, and / or glycine, protein hydrolysates and amino acids from both animal and plant sources, inorganic compounds (e.g., silica), and combinations thereof. According to some embodiments, the biostimulant is one or more Azospirillum extracts (e.g., an extract of a medium comprising A. brasilense INTA Az-39), one or more BradyRhizobium extracts (e.g., B. elkanii SEMIA 501, B. elkanii SEMIA 587, B. elkanii SEMIA 5019, B. japonicum NRRL B-50586 (also deposited as NRRL B-59565), B. japonicum NRRL B-50587 (also deposited as NRRL B-59566), B. japonicum NRRL B-50588 (NRRL B-50589), B. japonicum NRRL B-50589 (NRRL B-50581), B. japonicum NRRL B-50582 (NRRL B-50583), B. japonicum NRRL B-50584 (NRRL B-50585), B. japonicum NRRL B-50586 (NRRL B-50586), B. japonicum NRRL B-50587 (NRRL B-50588), B. japonicum NRRL B-50589 (NRRL B-50581), B. japonicum NRRL B-50582 (NRRL B-50583), B. japonicum NRRL B-50584 (NRRL B-50585), B. japonicum NRRL B-50586 (NRRL B-50586), B. japonicum NRRL B-50588 (NRRL B-50585), B. japonicum NRRL B-50589 (NRRL B-50585), B. japonicum NRRL B-5058 B-59567), B. japonicum NRRL B-50589 (also deposited as NRRL B-59568), B. japonicum NRRL B-50590 (also deposited as NRRL B-59569), B.B. japonicum NRRL B-50591 (also deposited as NRRL B-59570), B. japonicum NRRL B-50592 (also deposited as NRRL B-59571), B. japonicum NRRL B-50593 (also deposited as NRRL B-59572), B. japonicum NRRL B-50594 (also deposited as NRRL B-50493), B. japonicum NRRL B-50608, B. japonicum NRRL B-50609, B. japonicum NRRL B-50610, B. japonicum NRRL B-50611, B. japonicum NRRL B-50612, B. japonicum NRRL B-50726, B. japonicum NRRL B-50727, B. japonicum NRRL B-50728, B. japonicum NRRL B-50729, B. japonicum NRRL B-50730, B. japonicum SEMIA 566, B. japonicum SEMIA 5079, B. japonicum SEMIA 5080, B. japonicum USDA 6, B. japonicum USDA 110, B. japonicum USDA 122, B. japonicum USDA 123, B. japonicum USDA 127, B. japonicum USDA 129 and / or B. japonicum USDA 532C), one or more extracts (e.g., a Rhizobium extract (e.g., an extract of media comprising R. leguminosarum (R.leguminosarum SO12A-2), one or more Sinorhizobium extracts (e.g., an extract of a medium comprising S. fredii CCBAU114 and / or S. fredii USDA 205), one or more Penicillium extracts (e.g., P. bilaiae ATCC 18309, P. bilaiae ATCC 20851, P. bilaiae ATCC 22348, P. bilaiae NRRL 50162, P. bilaiae NRRL 50169, P. bilaiae NRRL 50776, P. bilaiae NRRL 50779, P. bilaiae NRRL 50821, P. bilaiae NRRL 50822, P. bilaiae NRRL 50823, P. bilaiae NRRL 50824, P. bilaiae NRRL 50825, P. bilaiae NRRL 50826, P. bilaiae NRRL 50827, P. bilaiae NRRL 50829, P. bilaiae NRRL 50828, P. bilaiae NRRL 50829 ... 50777, P.bilaiae NRRL 50778, P.bilaiae NRRL 50779, P.bilaiae NRRL 50780, P.bilaiae NRRL 50781, P.bilaiae NRRL 50782, P.bilaiae NRRL 50783, P.bilaiae NRRL 50784, P.bilaiae NRRL 50785, P.bilaiae NRRL 50786, P. bilaiae NRRL 50787, P. bilaiae NRRL 50788, P. bilaiae RS7B-SD1, P. brevicompactum AgRF18, P. canescens ATCC 10419, P. expansum ATCC 24692, P. expansum YT02, P. fellatanum ATCC 48694, P. gaestrivorus NRRL 50170, P. glabrum DAOM 239074, P.P. glabrum CBS 229.28, P. janthinellum ATCC 10455, P. lanosocoeruleum ATCC 48919, P. radicum ATCC 201836, P. radicum FRR 4717, P. radicum FRR 4719, P. radicum N93 / 47267 and / or P. raistrickii ATCC 10490), one or more Pseudomonas extracts (e.g., an extract of a medium comprising P. jessenii PS06), one or more acaricidal, insecticidal and / or nematicidal extracts (e.g., an extract of a medium comprising Bacillus firmus I-1582, Bacillus mycoides AQ726, NRRL B-21664; Beauveria bassiana ATCC-74040, Beauveria bassiana ATCC-74250, Burkholderia sp. A396 sp. nov. linogensis (nov.rinojensis, NRRL B-50319, Chromobacterium subtsugae NRRL B-30655, Chromobacterium vaccinii NRRL B-50880, Flavobacterium H492, NRRL B-50584, Metarhizium anisopliae F52 (Metarhizium anisopliae strain 52, Metarhizium anisopliae strain 7, Metarhizium anisopliae strain 43 and Metarhizium anisopliae anisopliae BIO-1020, also known as TAE-001; deposited as DSM 3884, DSM 3885, ATCC 90448, SD 170 and ARSEF 7711) and / or Paecilomyces fumosoroseus FE991), and / or one or more antifungal extracts (e.g. an extract of media comprising Ampelomyces quisqualis AQ 10® (Intrachem Bio GmbH & Co. KG, Germany), Aspergillus flavus AFLA-GUARD® (Syngenta Crop Protection, Inc., Switzerland), Aureobasidium pullulans BOTECTOR® (bio-ferm GmbH, Germany), Bacillus pumilus AQ717 (NRRL B-21662), Bacillus pumilus NRRL B-30087, Bacillus AQ175 (ATCC 55608), Bacillus AQ177 (ATCC 55609), Bacillus subtilis AQ713 (NRRL B-21661), Bacillus subtilis AQ743 (NRRL B-21665), Bacillus amyloliquefaciens amyloliquefaciens FZB24, Bacillus amyloliquefaciens NRRL B-50349, Bacillus amyloliquefaciens TJ1000 (1BE, also known as isolate ATCC BAA-390), Bacillus thuringiensis AQ52 (NRRL B-21619), Candida oleophila I-82 (e.g., ASPIRE®, Ecogen Inc., USA), Candida saitoana BIOCURE® (mixture with lysozyme BASF, USA) and BIOCOAT® (ArystaLife Science, Ltd., Cary, NC), Clonostachys rosea f. catenulata (Clonostachys rosea f.catenulata (also known as Gliocladium catenulatum) J1446 (PRESTOP®, Verdera, Finland), Coniothyrium minitans CONTANS® (Prophyta, Germany), Cryphonectria parasitica (CNICM, France), Cryptococcus albidus YIELD PLUS® (Anchor Bio-Technologies, South Africa), Fusarium oxysporum BIOFOX® (SIAPA, Italy) and FUSACLEAN® (Natural Plant Protection, France), Metschnikowia fructicola SHEMER® (Agrogreen, Israel), Microdochium dimerum ANTIBOT® (Agrauxine, France), Muscodor albus NRRL 30547, Muscodor roseus NRRL 30548, Phlebiopsis gigantea ROTSOP® (Verdera, Finland), Pseudozyma flocculosa SPORODEX® (Plant Products Co. Ltd., Canada), Pythium oligandrum DV74 (POLYVERSUM®, Remeslo SSRO, Biopreparaty, Czech Rep.), Raynautria sacrinensis. Reynoutria sachlinensis (e.g., REGALIA®, Marrone BioInnovations, USA), Streptomyces NRRL B-30145, Streptomyces M1064, Streptomyces galbus NRRL 30232, Streptomyces lydicus WYEC 108 (ATCC 55445), Streptomyces violaceusniger YCED 9 (ATCC 55660; DE-THATCH-9®, DECOMP-9® and THATCH CONTROL®, Idaho Research Foundation, USA), Streptomyces WYE 53 (ATCC 55750; DE-THATCH-9®, DECOMP-9® and THATCH CONTROL®, Idaho Research Foundation, USA), Talaromyces flavus V117b (PROTUS®, Prophyta, Germany), Trichoderma asperellum SKT-1 (ECO-HOPE®, Kumiai Chemical Industry Co., Ltd., Japan), Trichoderma atroviride LC52 (SENTINEL®, Agrimm Technologies Ltd, New Zealand), Trichoderma harzianum T-22 (PLANTSHIELD®, der Firma BioWorks Inc., USA), Trichoderma harzianum) TH-35 (ROOT PRO (registered trademark), Mycontrol Ltd., Israel), Trichoderma harzianum T-39 (TRICHODEX®, Mycontrol Ltd., Israel; TRICHODERMA 2000®, Makhteshim Ltd., Israel), Trichoderma harzianum ICC012 and Trichoderma viride TRICHOPEL (Agrimm Technologies Ltd, New Zealand), Trichoderma harzianum ICC012 and Trichoderma viride ICC080 (REMEDIER® WP, Isagro Ricerca, Italy), Trichoderma polysporum and Trichoderma harzianum (BINAB®, BINAB Bio-Innovation AB, Sweden), Trichoderma stromaticum TRICOVAB® (CEPLAC, Brazil), Trichoderma virens GL-21 (SOILGARD®, Certis LLC, USA), Trichoderma virens G1-3, ATCC 57678, Trichoderma virens G1-21 (Thermo Trilogy Corporation, Wasco, Canada), Trichoderma virens G1-3 and Bacillus amyloliquefaciens FZB2, Trichoderma virens G1-3 and Bacillus amyloliquefaciens NRRL B-50349, Trichoderma virens G1-3 and Bacillus amyloliquefaciens TJ1000, Trichoderma virens G1-21 and Bacillus amyloliquefaciens FZB24, Trichoderma virens G1-21 and Bacillus amyloliquefaciens NRRL B-50349, Trichoderma virens G1-21 and Bacillus amyloliquefaciens TJ1000, Trichoderma viride TRIECO® (Ecosense Labs.(India)Pvt.Ltd., India, BIO-CURE®F, T. Stanes & Co.Ltd., India), Trichoderma viride TV1 (Agribiotec srl, Italy), Trichoderma viride ICC080, and / or Ulocladium oudemansii HRU3 (BOTRY-ZEN®, Botry-Zen Ltd, New Zealand), and extracts of media comprising these combinations.

[0122] According to some embodiments, the compound combinations and compositions of the present invention may be combined with one or more lipochitooligosaccharides (LCOs), chitooligosaccharides (COs), and / or chitinous compounds. LCOs, sometimes called symbiotic nodulation (Nod) signals (or Nod factors) or Myc factors, consist of an oligosaccharide backbone of β-1,4-linked N-acetyl-D-glucosamine ("GlcNAc") residues with a condensed N-linked fatty acyl chain at the non-reducing end. As understood in the art, LCOs vary in the number of GlcNAc residues in the backbone, the length and degree of saturation of the fatty acyl chain, and the substitution of reducing or non-reducing sugar residues. See, e.g., Denarie et al., Ann. Rev. Biochem. 65:503 (1996); Diaz et al., Mol. Plant-Microbe Interactions 13:268 (2000); Hungria et al., Soil Biol. Biochem. 29:819 (1997); Hamel et al., Planta 232:787 (2010); and Prome et al., Pure & Appl. Chem. 70(1):55 (1998).

[0123] LCO (and its derivatives) may be included or utilized in various purity forms, either alone or in the form of a culture of LCO producing bacteria or fungi. For example, OPTIMIZE® (commercially available from Bayer) contains a culture of LCO producing Bradyrhizobium japonicum. Methods for providing substantially pure LCO include removing bacterial cells from a mixture of LCO and microorganisms, or LCO solvent phase separation as described in U.S. Pat. No. 5,549,718, followed by isolating and purifying the LCO molecule by HPLC chromatography. Purification can be accelerated by repeated HPLC chromatography, and the purified LCO molecule can be lyophilized for long-term storage. The compositions and methods of the present disclosure may include analogs, derivatives, hydrates, isomers, isomers, and / or solvates of LCO. LCO may be incorporated into compositions according to the present invention up to any suitable amount / concentration. For example, compositions according to the present invention may be incorporated in amounts up to about 1×10 -20 M ~ approx. 1×10 -1 The composition comprises an LCO of M. The amount / concentration of the LCO can be an amount effective to impart a desired trait or benefit to a plant, such as to enhance the growth and / or yield of a plant to which the composition is applied. According to some embodiments, the LCO amount / concentration is not effective to enhance the yield of a plant without a beneficial contribution from one or more other components of the composition, such as CO and / or one or more pesticides.

[0124] The compound combinations and compositions of the present invention may be combined with any suitable CO, possibly in combination with one or more LCOs. COs differ from LCOs in that they do not have the fatty acid pendant chains characteristic of LCOs. COs are called N-acetyl-chitooligosaccharides and consist of GlcNAc residues, but are not bound to the chitin molecule [(CH 13 No. 5) n , CAS No. 1398-61-4] and chitosan molecule [(C 11 No. 4) n, CAS No. 9012-76-4]. For example, D'Haeze et al., Glycobiol. 12(6):79R (2002); Demont-Caulet et al., Plant Physiol. 120(1):83 (1999); Hanel et al., Planta 232:787 (2010); Muller et al., Plant Physiol. 124:733 (2000); Robina et al., Tetrahedron 58:521-530 (2002); Rouge et al., Docking of Chitin Oligomers and Nod Factors on Lectin Domains of the LysM-RLK Receptors in the Medicago-Rhizobium Symbiosis, in The Molecular Immunology of Complex Carbohydrates-3 (Springer Science, 2011); Van der Holst et al. al., Curr. Opin. Struc. Biol. 11:608 (2001); and Wan et al., Plant Cell 21:1053 (2009). CO may be obtained from any suitable source. For example, CO may be derived from LCO. For example, in embodiments, compositions according to the invention comprise one or more COs derived from a LCO (i.e., isolated and / or purified) obtained from a strain of Azorhizobium, Bradyrhizobium (e.g., B. japonicum), Mesorhizobium, Rhizobium (e.g., R. leguminosarum), Sinorhizobium (e.g., S. meliloti), or a mycorrhizal fungus (e.g., Glomus intraradicus). Alternatively, the CO may be synthetic. Methods for preparing recombinant CO are known in the art.See, e.g., Cottaz et al., Meth. Eng. 7(4):311 (2005); Samain et al., Carbohydrate Res. 302:35 (1997.); and Samain et al., J. Biotechnol. 72:33 (1999), the contents and disclosures of which are incorporated herein by reference.

[0125] CO (and its derivatives) may be included or utilized in various purity forms and may be used alone or in the form of a culture medium of CO producing bacteria or fungi. It should be understood that the compound combinations and compositions according to the present invention may be combined with hydrates, isomers, salts and / or solvates of CO. CO may be used in any suitable amount / concentration. For example, the compound combinations and compositions according to the present invention may be combined with hydrates, isomers, salts and / or solvates of CO. CO may be used in any suitable amount / concentration. For example, the compound combinations and compositions according to the present invention may be combined with hydrates, isomers, salts and / or solvates of CO. -20 M ~ approx. 1×10 -1 The composition may comprise M CO. The amount / concentration of CO may be an amount effective to impart or confer a favorable trait or benefit to a plant, such as to enhance the soil microbial environment, nutrient uptake, or increase the growth and / or yield of a plant to which the composition is applied. According to some embodiments, the amount / concentration of CO may not be effective to enhance plant growth without beneficial contributions from one or more other components of the composition, such as LCO and / or one or more inoculants, biomolecules, nutrients, or pesticides.

[0126] The compound combination and composition of the present invention may be combined with one or more suitable chitinous compounds, such as chitin, chitosan, and their isomers, salts and solvates. Chitin and chitosan, which are the main components of fungal cell walls and insect and crustacean exoskeletons, are composed of GlcNAc. Chitin and chitosan may be commercially obtained or may be prepared from insect, crustacean shells, or fungal cell walls. Methods for preparing chitin and chitosan are known in the art. See, for example, U.S. Patent Nos. 4,536,207 (prepared from crustacean shells) and 5,965,545 (prepared from crab shells and hydrolysis of commercially available chitosan); and Pochanavanich et al., Lett. Appl. Microbiol. 35:17 (2002) (prepared from fungal cell walls). Deacetylated chitin and chitosan may be obtained ranging from less than 35% to more than 90% deacetylation and covering a broad spectrum of molecular weights, e.g., low molecular weight chitosan oligomers less than 15 kD and chitin oligomers between 0.5 and 2 kD; "Practical Grade" chitosans of molecular weights of about 15 kD; and high molecular weight chitosans up to 70 kD. Chitin and chitosan compositions formulated for treatment are commercially available. Commercially available products include, for example, ELEXA® (Plant Defense Boosters, Inc.) and BEYOND™ (Agrihouse, Inc.).

[0127] The compound combination and composition of the present invention may be combined with one or more suitable flavonoids, including but not limited to anthocyanidins, anthoxanthins, chalcones, coumarins, flavonones, flavanonols, flavans and isoflavonoids, and their analogs, derivatives, hydrates, isomers, polymers, salts and solvates.Flavonoids are phenolic compounds with a general structure of two aromatic rings connected by a three-carbon bridge. Classification of flavonoids is known in the art. See, for example, Jain et al., J. Plant Biochem. & Biotechnol. 11:1 (2002); and Shaw et al., Environ. Microbiol. 11:1867 (2006). The contents and disclosures of which are incorporated herein by reference. Some flavonoid compounds are commercially available. Flavonoid compounds may be isolated from plants or seeds, for example, as described in U.S. Patent Nos. 5,702,752; 5,990,291; and 6,146,668.Flavonoid compounds may also be produced by genetically engineered organisms such as yeast.See, for example, Ralston et al., Plant Physiol. 137:1375 (2005).

[0128] According to some embodiments, the compound combinations and compositions of the present invention can be administered in the form of one or more flavanones, such as one or more of butin, eriodictyol, hesperetin, hesperidin, homoeriodictyol, isosakuranetin, naringenin, naringin, pinocembrin, poncirin, sakuranetin, sakuranin, and / or sterubin, one or more flavanonols, such as dihydrokaempferol and / or taxifolin, one or more flavan-3-ols (e.g., catechin (C), catechin 3-gallate (Cg), epicatechins (EC), , epigallocatechin (EGC), epicatechin 3-gallate (ECg), epigallocatechin 3-gallate (EGCg), epiafzelechin, fisetinidol, gallocatechin (GC), gallocatechin 3-gallate (GCg), guiburtinidol, mesquitol, robinetinidol, theaflavin-3-gallate, theaflavin-3'-gallate, teflavin-3,3'-gallate, thearubigins), flavan-4-ols (e.g. apifolorol and / or luteophorol) and / or flavan-3,4-diols (e.g. leucocyanidol, one or more flavans, such as leucopentin, leucopeonidin, leucorobinetinidin, melacacidin and / or teracacidin, and / or dimers, trimers, oligomers and / or polymers thereof (e.g., one or more proanthocyanidins), one or more isoflavones or flavonoid derivatives (e.g., biochanin A, daidzein, formononetin, genistein and / or glycitein), isoflavans (e.g., equol, ion cocarpan and / or laxifluoran), isoflavandiols, isoflavenes (e.g., glabrene, haginine D and / or 2-methoxyjudaicin), coumestans (e.g., coumestrol, plicadin and / or wedelolactone), pterocarpans, rhoetonoids, neoflavonoids (e.g., carophyllolide, coutareagenin, dalbergichromene, dalbergin, nivethin), and / or pterocarpans (e.g., bitucarpine A, bitucarpine B, eriblaedin A,It may be combined with one or more isoflavonoids, such as erythraedin B, erythrabyssin II, erythrabyssin-1, erycristagallin, glycinol, glyceolidins, glyceollins, glycirisol, maackiain, medicarpin, moricyanin, orientanol, phaseolin, pisatin, striatin, trifoliridin, and combinations thereof. Flavonoids and their derivatives may be included in the composition in any suitable form, including but not limited to polymorphs and crystalline forms. Flavonoids may be included in the composition in any suitable amount or concentration. The amount / concentration of flavonoids may be an amount effective to provide benefits to plants, and may act directly on soil microorganisms or other means, such as to enhance plant nutrients and / or yield. According to some embodiments, the amount / concentration of flavonoids may not be effective to enhance plant nutrition or yield without beneficial contributions from one or more other components of the composition, such as LCO, CO and / or one or more pesticides.

[0129] The compound combinations and compositions of the present invention may be combined with one or more suitable non-flavonoid nod gene inducers, including, but not limited to, jasmonic acid ([1R-[1α,2β(Z)]]-3-oxo-2-(pentenyl)cyclopentaneacetic acid; JA), linoleic acid ((Z,Z)-9,12-octadecadienoic acid) and / or linolenic acid ((Z,Z,Z)-9,12,15-octadecatrienoic acid), and analogs, derivatives, hydrates, isomers, polymers, salts and solvates thereof. Jasmonic acid and its methyl ester, collectively known as jasmonates, methyl jasmonate (MeJA), are octadecanoid-based compounds that occur naturally in some plants (e.g., wheat), fungi (e.g., Botryodiplodia theobromae, Gibberella fujikuroi), enzymes (e.g., Saccharomyces cerevisiae), and bacteria (e.g., Escherichia coli). Linoleic and linolenic acids may be produced during the biosynthesis of jasmonic acid. Jasmonates, linoleic and linolenic acids (and their derivatives) have been reported to be inducers of nod gene expression or LCO production by rhizobacteria. For example, Mabood et al., Plant Physiol. Biochem. 44(11):759 (2006); Mabood et al., Agr. J. 98(2):289 (2006); Mabood et al., Field Crops Res.95(2-3):412 (2006); and Mabood & Smith, Linoleic and linolenic acid induce the expression of nod See Genes in Bradyrhizobium japonicum USDA 3, Plant Biol. (2001).

[0130] Derivatives of jasmonic acid, linoleic acid, and linolenic acid that may be included in or used in combination with the compound combinations and compositions of the present invention include esters, amides, glycosides, and salts thereof. Exemplary esters are compounds in which the carboxyl group of linoleic acid, linolenic acid, or jasmonic acid is replaced by a COR group, where R is R 1 is: an alkyl group such as a C1-C8 unbranched or branched alkyl group, for example a methyl, ethyl or propyl group; an alkenyl group such as a C2-C8 unbranched or branched alkenyl group; an alkynyl group such as a C2-C8 unbranched or branched alkynyl group; an aryl group, for example having 6-10 carbon atoms; or a heteroaryl group, for example having 4-9 carbon atoms, wherein the heteroatom in said heteroaryl group can be, for example, N, O, P or S, OR 1 Representative amides are compounds in which the carboxyl group of linoleic acid, linolenic acid, or jasmonic acid is replaced by a COR group, where R is R 2 and R 3 are each independently: hydrogen; an alkyl group such as a C1-C8 unbranched or branched alkyl group, for example, a methyl, ethyl, or propyl group; an alkenyl group such as a C2-C8 unbranched or branched alkenyl group; an alkynyl group such as a C2-C8 unbranched or branched alkynyl group; an aryl group, for example, having 6 to 10 carbon atoms; or a heteroaryl group, for example, having 4 to 9 carbon atoms, wherein the heteroatom in the heteroaryl group can be, for example, N, O, P, or S, NR 2 R 3The esters may be prepared by known methods such as acid-catalyzed nucleophilic addition reactions in which a carboxylic acid is reacted with an alcohol in the presence of a catalytic amount of a mineral acid. Amides may be prepared by known methods such as by reacting a carboxylic acid with a suitable amine in the presence of a coupling agent such as dicyclohexylcarbodiimide (DCC) under neutral conditions. Suitable salts of linoleic acid, linolenic acid and jasmonic acid include, for example, base addition salts. Bases that may be used as reagents to prepare metabolically acceptable base salts of these compounds include those derived from cations such as alkali metal cations (e.g., potassium and sodium) and alkaline earth metal cations (e.g., calcium and magnesium). These salts can be readily prepared by mixing a solution of linoleic acid, linolenic acid, or jasmonic acid with a solution of the base. The salts may precipitate from solution and be collected by filtration or may be recovered by other means, such as by evaporation of the solvent.

[0131] Non-flavonoid nod gene inducers may be used in combination with the compound combinations and compositions of the present invention in any suitable amount / concentration. For example, the amount / concentration of the non-flavonoid nod gene inducer may be an amount effective to impart or confer a favorable trait or benefit to a plant, such as to enhance the growth and / or yield of a plant to which the composition is applied. According to some embodiments, the amount / concentration of the non-flavonoid nod gene inducer may not be effective to enhance the growth and / or yield of a plant without a beneficial contribution from one or more other components of the composition, such as LCO, CO, and / or one or more insecticides.

[0132] The compound combination and composition of the present invention may be combined with karakines, including, but not limited to, 2H-furo[2,3-c]pyran-2-one, and their analogs, derivatives, hydrates, isomers, polymers, salts and solvates. Examples of biologically acceptable salts of karakines include acid addition salts formed with biologically acceptable acids, including hydrochloride, hydrobromide, sulfate or bisulfate, phosphate or hydrogen phosphate, acetate, benzoate, succinate, fumarate, maleate, lactate, citrate, tartrate, gluconate; methanesulfonate, benzenesulfonate and p-toluenesulfonate. Additional biologically acceptable metal salts may include alkali metal salts with bases, including sodium and potassium salts. Karakines may be incorporated into the composition according to the present invention in any suitable amount or concentration. For example, the amount / concentration of the karachins can be an amount effective to impart or confer a desirable trait or benefit to a plant, such as to enhance the growth and / or yield of a plant to which the composition is applied. In embodiments, the amount / concentration of the karachins may not be effective to enhance the nutrients and / or yield of a plant without beneficial contributions from one or more other components of the composition, such as an LCO, CO, and / or one or more insecticides.

[0133] The compound combinations and compositions of the present invention may be administered with or without the use of any of the following compounds: cyanidin, delphinidin, malvidin, pelargonidin, peonidin, petunidin, flavones (e.g., apigenin, baicalein, chrysin, 7,8-dihydroxyflavone, diosmin, flavoxate, 6-hydroxyflavone, luteolin, scutellarein, tangeritin, and / or wogonin) and / or flavonols (e.g., amurensin, astragalin, azaleatin, azalein, fisetin, furanoflavonol galangin, goat, galangin ... It may be combined with one or more anthocyanidins and / or anthoxanthins, such as one or more of cypetin, 3-hydroxyflavone, hyperoside, icariin, isoquercetin, kaempferide, kaempferitrin, kaempferol, isorhamnetin, morin, myricetin, myricitrin, natudaidin, pachypodin, pyranoflavonol quercetin, quercetin, rhamnadin, rhamnetin, robinin, rutin, spireosides, troxerutin and / or xanthamnin, and combinations thereof.

[0134] The compound combinations and compositions of the present invention may be combined with gluconolactone and / or their analogs, derivatives, hydrates, isomers, polymers, salts and / or solvates. Gluconolactone may be incorporated into the compositions according to the present invention to any suitable amount / concentration. For example, the amount / concentration of gluconolactone may be an amount effective to impart or provide a favorable trait or benefit to the plant, such as to enhance the growth and / or yield of the plant to which the composition is applied. In an embodiment, the amount / concentration of gluconolactone may not be effective to enhance the nutrients and / or yield of the plant without beneficial contribution from one or more other components of the composition, such as LCO, CO and / or one or more insecticides.

[0135] The compound combinations and compositions of the present invention may be administered in the form of supplements, such as supplements containing organic acids (e.g., acetic acid, citric acid, lactic acid, malic acid, taurine, etc.), major minerals (e.g., phosphorus, calcium, magnesium, potassium, sodium, iron, etc.), trace minerals (e.g., boron, cobalt, chloride, chromium, copper, fluoride, iodide, iron, manganese, molybdenum, selenium, zinc, etc.), vitamins (e.g., vitamin A, vitamin B complex (i.e., vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B7, vitamin B8, vitamin B9, vitamin B10, vitamin B11, vitamin B12, vitamin B13, vitamin B14, vitamin B15, vitamin B16, vitamin B17, vitamin B18, vitamin B19, vitamin B20, vitamin B21, vitamin B22, vitamin B23, vitamin B24, vitamin B25, vitamin B26, vitamin B27, vitamin B28, vitamin B29, vitamin B30, vitamin B31, vitamin B32, vitamin B33, vitamin B34, vitamin B35, vitamin B36, vitamin B37, vitamin B38, vitamin B39, vitamin B40, vitamin B41, vitamin B42, vitamin B43, vitamin B44, vitamin B45, vitamin B46, vitamin B47, vitamin B48, vitamin B50, vitamin B51, vitamin B52, vitamin B53, vitamin B54, vitamin B55, vitamin B56, vitamin B57, vitamin B58, vitamin B60, vitamin B61, vitamin B62, vitamin B63, vitamin B64, vitamin B65, vitamin B66, vitamin B67, vitamin B68, vitamin B69, vitamin B70, vitamin B71, vitamin B72, vitamin B73, vitamin B74, vitamin B75, vitamin B7 12 , choline), vitamin C, vitamin D, vitamin E, vitamin K), and / or carotenoids (alpha-carotene, beta-carotene, cryptoxanthin, lutein, lycopene, zeaxanthin, etc.), and combinations thereof. In aspects, the compound combinations and compositions according to the present invention may be combined with plant or microbial macronutrients and micronutrients, including phosphorus, boron, choline, copper, iron, manganese, molybdenum, and / or zinc. According to some embodiments, the compound combinations and compositions according to the present invention may be combined with one or more beneficial micronutrients. Non-limiting examples of micronutrients for use in the compositions described herein include vitamins (vitamin A, vitamin B complex (i.e., vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B7, vitamin B8, vitamin B9, vitamin B10, vitamin B11, vitamin B12, vitamin B13, vitamin B14, vitamin B15, vitamin B16, vitamin B17, vitamin B18, vitamin B19, vitamin B20, vitamin B21, vitamin B22, vitamin B23, vitamin B24, vitamin B25, vitamin B26, vitamin B27, vitamin B28, vitamin B29, vitamin B30, vitamin B31, vitamin B32, vitamin B33, vitamin B34, vitamin B35, vitamin B36, vitamin B37, vitamin B38, vitamin B39, vitamin B40, vitamin B41, vitamin B42, vitamin B43, vitamin B44, vitamin B45, vitamin B46, vitamin B47, vitamin B48, vitamin B50, vitamin B51, vitamin B52, vitamin B53, vitamin B54, vitamin B55, vitamin B56, vitamin B57, vitamin B58, vitamin B60, vitamin B61, vitamin B62, vitamin B63, vitamin B64, vitamin B65, vitamin B66, vitamin B67, vitamin B68 12, choline), vitamin C, vitamin D, vitamin E, vitamin K), carotenoids (alpha-carotene, beta-carotene, cryptoxanthin, lutein, lycopene, zeaxanthin, etc.), major minerals (e.g., phosphorus, calcium, magnesium, potassium, sodium, iron, etc.), trace minerals (e.g., boron, cobalt, chloride, chromium, copper, fluoride, iodide, iron, manganese, molybdenum, selenium, zinc, etc.), and combinations thereof (BAYFOLAN secure, BAYFOLAN complete, BAYFOLAN energy, BAYFOLAN power, Aglukon GmbH, Germany). In certain embodiments, the composition may comprise phosphorus, boron, chlorine, copper, iron, manganese, molybdenum, and / or zinc, and combinations thereof. For compositions comprising phosphorus, it is contemplated that any suitable source of phosphorus may be used. For example, phosphorus may be from a phosphate rock source, such as monoammonium phosphate, diammonium phosphate, monocalcium phosphate, superphosphate, triple superphosphate, and / or ammonium polyphosphate, an organic phosphorus source that can be solubilized by one or more microorganisms (e.g., Penicillium bilaiae), or a phosphorus source.

[0136] Methods and Uses The compound combination and composition of the present invention have strong antibacterial and / or plant defense regulation ability.They can be used to control unwanted microorganisms, such as unwanted fungi and bacteria, on plants.As described in more detail below, they can be particularly useful for crop protection (they control the microorganisms that cause plant diseases) or for protecting materials (e.g., industrial materials, wood plants, holdings).More specifically, the compound combination and composition of the present invention can be used to protect seeds, germinated seeds, emergent seedlings, plants, plant parts, fruits, harvested products and / or the soil in which plants grow from unwanted microorganisms.

[0137] As used herein, control or control includes protective, curative and eradicating treatments of unwanted microorganisms. Unwanted microorganisms may be pathogenic bacteria, pathogenic viruses, pathogenic oomycetes or pathogenic fungi, more specifically, phytopathogenic bacteria, phytopathogenic viruses, phytopathogenic oomycetes or phytopathogenic fungi. As detailed herein below, these phytopathogenic microorganisms are the cause of a broad spectrum of plant diseases.

[0138] More particularly, the compound combination and composition of the present invention can be used as antifungal agent.For the purpose of description, the term "antifungal agent" refers to a compound or composition that can be used in crop protection for controlling unwanted fungi such as Plasmodiophoromycetes, Chytridiomycetes, Zygosaccharomyces, Ascomycetes, Basidiomycetes and Deuteromycetes, and / or for controlling oomycetes.

[0139] The compound combinations and compositions of the present invention may be used as antibacterial agents.In particular, they may be used in crop protection, for example in controlling unwanted bacteria such as Pseudomonadaceae, Rhizobiaceae, Xanthomonadaceae, Enterobacteriaceae, Corynebacteriaceae and Streptomycetaceae.

[0140] The present invention also relates to a method for controlling undesirable microorganisms, such as undesirable fungi, oomycetes and bacteria, on plants, said method comprising the step of applying a compound combination or composition of the present invention to the microorganisms and / or their habitat (on the plants, plant parts, seeds, fruits or on the soil in which the plants grow), in which compounds (A) and (B) and optionally (C) may be applied simultaneously, separately or sequentially. In the case of sequential application of single compounds, i.e., one after the other at different times within a reasonably short period of time, such as a few hours or days.

[0141] Usually, when the compound combination and composition of the present invention are used in a curative or protective method for controlling phytopathogenic fungi and / or phytopathogenic oomycetes, their effective amount and plant-compatible amount are applied to plants, plant parts, fruits, seeds, or the soil or substrate on which the plants grow.Suitable substrates that may be used to grow plants include inorganic substrates such as mineral wool, especially stone wool, perlite, sand or gravel; organic substrates such as peat, pine bark or sawdust; and petroleum-based substrates such as polymer foam or plastic beads.Effective amount and plant-compatible amount refer to an amount that is sufficient to control or destroy the fungi that tend to exist or appear on agricultural land, and does not cause any noticeable signs of phytotoxicity to said crop.Such amount can vary within a wide range depending on the fungi to be controlled, the type of crop, the growth stage of the crop, climatic conditions and each compound or composition of the present invention used.This amount can be determined by systematic field tests, which are within the ability of a person skilled in the art.

[0142] Plants and plant parts The compound combinations and compositions of the present invention may be applied to any plant or plant part.

[0143] Plants refer to all plants and groups of plants, such as desired and undesired wild plants or crops (including natural crops). Crops may be obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or a combination thereof, and may include genetically modified plants (GMOs or transgenic plants) and protected and unprotected plant cultivars under plant breeders' rights.

[0144] Plant cultivars are understood to mean plants having novel properties ("genetic traits") and obtained by conventional breeding, mutagenesis or recombinant DNA techniques. These may be cultivars, varieties, biotypes or genotypes.

[0145] Plant parts are understood to mean all parts and organs of a plant above and below the ground, such as shoots, leaves, needles, stalks, stems, flowers, fruiting bodies, fruits, seeds, roots, tubers and rhizomes, etc. Plant parts also include harvested material as well as plant material and reproductive propagation material, such as cuttings, tubers, rhizomes, seedlings and seeds.

[0146] Plants which may be treated according to the method of the invention include cotton, flax, grapes, fruits, vegetables, such as Rosaceae sp. (e.g. pome fruits such as apple and pear, but also stone fruits such as apricots, cherries, almonds and peaches, and soft fruits such as strawberries), Ribesioidae sp., Juglandaceae sp., Betulaceae sp., Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae sp., Actinidaceae sp., Lauraceae sp., Musaceae sp. sp. (e.g. banana trees and plantations), Rubiaceae sp. (e.g. coffee), Theaceae sp., Sterculiceae sp., Rutaceae sp. (e.g. lemon, orange and grapefruit); Solanaceae sp. (e.g. tomato), Liliaceae sp., Asteraceae sp. (e.g. lettuce), Umbelliferae sp., Cruciferae sp., Chenopodiaceae sp., Cucurbitaceae sp. (e.g. cucumber), Alliaceae sp. sp. (e.g., leek, onion), Papilionaceae sp. (e.g., pea); major crops, e.g., Gramineae sp. (e.g., corn, grass, cereals, e.g., wheat, rye, rice, barley, oats, millet and triticale), Asteraceae sp. (e.g., sunflower), Brassicaceae sp.) (e.g., white cabbage, red cabbage, broccoli, cauliflower, Brussels sprouts, bok choy, turnip cabbage, radish, and rapeseed, mustard, horseradish, and watercress), Fabacae sp. (e.g., beans, peanuts), Papilionaceae sp. (e.g., soybeans), Solanaceae sp. (e.g., potatoes), Chenopodiaceae sp., etc. .

[0147] Plants and plant cultivars that may be treated by the disclosed methods include plants and plant cultivars that are tolerant to one or more biotic stresses, i.e., the plants exhibit better defense against animal and microbial pests, such as nematodes, insects, mites, phytopathogenic fungi, bacterial viruses and / or viroids.

[0148] The plants and plant cultivars that can be treated by the above-disclosed method include plants that are tolerant to one or more abiotic stresses.Abiotic stress conditions can include, for example, drought, low temperature exposure, heat exposure, osmotic stress, flooding, increased soil salinity, increased mineral exposure, ozone exposure, high light exposure, limited availability of nitrogen nutrients, limited availability of phosphorus nutrients, and shade avoidance.

[0149] Plants and plant cultivars that can be treated by the disclosed method include plants that are characterized by enhanced yield characteristics. The increased yield of the plants can be the result of, for example, water use efficiency, water retention efficiency, improved nitrogen use, enhanced carbon assimilation, improved photosynthesis, increased germination efficiency and accelerated maturation. Furthermore, yield is influenced by improved plant architecture (under stress and non-stress conditions), including, but not limited to, early flowering, flowering control for hybrid seed production, seedling vigor, plant size, internode number and distance, root growth, seed size, fruit size, pod size, pod or panicle number, seed number per pod or panicle, seed mass, enhanced seed maturation, reduced seed scattering, reduced pod dehiscence and lodging resistance. Further yield characteristics include seed composition, such as carbohydrate content and composition, for example cotton or starch, protein content, oil content and composition, nutritional value, reduction of non-nutritional compounds, improved processability and better storage stability.

[0150] Plants and plant cultivars that can be treated by the disclosed methods generally include hybrid plants that already express heterosis or hybrid vigor traits that result in higher yields, vigor, health and resistance to biotic and abiotic stresses.

[0151] Transgenic plants, seed treatments and integration events The compound combinations according to the invention can be advantageously used to treat transgenic plants, plant cultivars or plant parts that have received genetic material that confers advantageous and / or useful properties (traits) to these plants, plant cultivars or plant parts. It is therefore contemplated that the present invention may be combined with one or more recombinant traits or transgenic events or combinations thereof. For the purposes of this application, a transgenic event is created by inserting a specific recombinant DNA molecule into a specific location (locus) within a chromosome of the plant genome. The insertion creates a new DNA sequence, called an "event", and is characterized by some amount of inserted recombinant DNA and genomic DNA located immediately adjacent / flanking both ends of the inserted DNA. Such traits or transgenic events include, but are not limited to, pest resistance, water use efficiency, yield, drought tolerance, seed quality, improved nutritional value, hybrid seed production, and herbicide resistance, said traits being measured relative to a plant that does not have such trait or transgenic event. Specific examples of such advantageous and / or useful properties (traits) are better plant growth, vigor, stress resistance, uprightness, lodging resistance, nutrient uptake, plant nutrition and / or yield, in particular improved growth, increased tolerance to high or low temperatures, increased tolerance to drought or water or soil salinity levels, enhanced flowering performance, easier harvesting, accelerated ripening, higher yields, higher quality and / or higher nutritional value of the harvested product, better storage life and / or processability of the harvested product, and increased resistance to animal and microbial pests such as insects, arachnids, nematodes, mites, slugs and snails.

[0152] Among the DNA sequences encoding proteins that confer protective properties of resistance against such animal and microbial pests, particularly insects, there may be mentioned genetic material from Bacillus thuringiensis encoding Bt proteins, which have been widely described in the literature and are well known to those skilled in the art, as well as proteins extracted from bacteria such as Photorhabdus (WO 97 / 17432 and WO 98 / 08932).In particular, CrylA, CryIAb, CryIAc, CryIIA, CryIIIA, CryIIIB2, Cry9c Cry2Ab, Cry3Bb and CryIF proteins or toxic fragments thereof, as well as hybrids or combinations thereof, in particular CrylF protein or hybrids derived from CrylF protein (e.g. hybrid CrylA-CrylF protein or toxic fragments thereof), CrylA type proteins or toxic fragments thereof, preferably CrylAc protein or hybrids derived from CrylAc protein (e.g. hybrid CrylAb CrylAc protein) or CrylAb or Bt2 protein or toxic fragments thereof, Cry2Ae, Cry2Af or Cry2Ag protein or toxic fragments thereof, CrylA.105 protein or toxic fragments thereof, VIP3Aa19 protein, VIP3Aa20 protein, VIP3A protein produced in COT202 or COT203 cotton events, Estruch et al. (1996), Proc Natl Acad Sci US A. 28;93(11):5389-94, or a toxic fragment thereof, Cry proteins as described in WO 2001 / 47952, Bt Cry or VIP proteins including insecticidal proteins from Xenorhabdus (described in WO 98 / 50427), Serratia (particularly from S. entomophila) or Photorhabdus species strains, such as the Tc-protein from Photorhabdus described in WO 98 / 08932. Also included herein are any variants or mutants of any one of these proteins that differ in a few amino acids (1-10, preferably 1-5) from any of the above named sequences, particularly the sequences of these toxic fragments, or fused to a transit peptide, such as a plastid transit peptide, or to another protein or peptide.

[0153] Another and particularly highlighted example of such a property is the conferring of resistance to one or more herbicides, such as imidazolinones, sulfonylureas, glyphosate or phosphinothricin. Among the DNA sequences encoding proteins that confer the property of resistance to specific herbicides in transformed plant cells and plants, particular mention may be made of the bar or PAT genes described in WO 2009 / 152359 or Streptomyces coelicolor genes that confer resistance to glyphosinate herbicides, genes encoding suitable EPSPS (5-enolpyruvylshikimate 3-phosphate synthase) that confer resistance to herbicides having EPSPS as target, in particular herbicides such as glyphosate and its salts, genes encoding glyphosate-n-acetyltransferase or genes encoding glyphosate oxidoreductase. Additional suitable herbicide tolerance traits include at least one ALS (acetolactate synthase) inhibitor (e.g., WO 2007 / 024782), a mutated Arabidopsis ALS / AHAS gene (e.g., U.S. Pat. No. 6,855,533), a gene encoding a 2,4-D-monooxygenase that confers tolerance to 2,4-D (2,4-dichlorophenoxyacetic acid), and a gene encoding a dicamba monooxygenase that confers tolerance to dicamba (3,6-dichloro-2-methoxybenzoic acid).

[0154] Yet another example of such a property is resistance to one or more plant pathogenic fungi, such as Asian soybean rust. Among the DNA sequences encoding proteins that confer such disease resistance properties, particular mention is made of genetic material from Glycine tomentella, for example from any one of the publicly available accessions PI441001, PI483224, PI583970, PI446958, PI499939, PI505220, PI499933, PI441008, PI505256 or PI446961, as described in WO 2019 / 103918.

[0155] Further and particularly highlighted examples of such properties are, for example, systemic acquired resistance (SAR), systemin, phytoalexins, elicitors, and also resistance genes and increasing resistance to bacteria and / or viruses by correspondingly expressed proteins and toxins.

[0156] Particularly useful transgenic events in transgenic plants or plant cultivars which can be preferably treated according to the invention are: event 531 / PV-GHBK04 (cotton, insect control, described in WO 2002 / 040677), event 1143-14A (cotton, insect control, not deposited, described in WO 2006 / 128569); event 1143-51B (cotton, insect control, deposited Event 1445 (cotton, herbicide resistance, not deposited, described in U.S. Patent Application Publication No. 2002 / 120964 or WO 2002 / 034946); Event 17053 (rice, herbicide resistance, deposited as PTA-9843, described in WO 2010 / 117737); Event 17314 (rice, herbicide resistance, deposited as PTA-9844 Event 281-24-236 (cotton, insect control-herbicide resistance, deposited as PTA-6233, described in WO 2005 / 103266 or U.S. Patent Application Publication No. 2005-216969); Event 3006-210-23 (cotton, insect control-herbicide resistance, deposited as PTA-6233, described in U.S. Patent Application Publication No. 2007-143876 or WO 2007-143876); Event 3272 (maize, quality traits, deposited as PTA-9972, and described in WO 2006 / 098952 or U.S. Patent Application Publication No. 2006 / 230473); Event 33391 (wheat, herbicide resistance, deposited as PTA-2347, and described in WO 2002 / 027004), Event 40416 (maize, insect control-herbicide resistance, deposited as PTA-2347, and described in ATCC PTA-11508, described in WO 11 / 075593); Event 43A47 (maize, insect control - herbicide resistance, deposited as ATCC PTA-11509, described in WO 2011 / 075595); Event 5307 (maize, insect control, deposited as ATCC PTA-9561, described in WO 2010 / 077816);Event ASR-368 (bentgrass, herbicide resistant, deposited as ATCC PTA-4816, described in U.S. Patent Application Publication No. 2006-162007 or WO 2004 / 053062); Event B16 (corn, herbicide resistant, not deposited, described in U.S. Patent Application Publication No. 2003-126634); Event BPS-CV127-9 (soybean, herbicide resistant, NCIMB No. 41603, described in WO 2010 / 080829); event BLRl (rapeseed, restoration of male sterility, deposited as NCIMB41193, described in WO 2005 / 074671), event CE43-67B (cotton, insect control, deposited as DSMACC2724, described in U.S. Patent Application Publication No. 2009 / 217423 or WO 2006 / 128573); event CE44-69D (cotton, insect control, not deposited, described in U.S. Patent Application Publication No. 2010 / 0024077); event CE44-69D (cotton, insect control, deposited event CE46-02A (cotton, insect control, not deposited, described in WO 2006 / 128572); event COT102 (cotton, insect control, not deposited, described in U.S. Patent Application Publication No. 2006 / 130175 or WO 2004 / 039986); event COT202 (cotton, insect control, not deposited, described in U.S. Patent Application Publication No. 2007 / 067868 or WO 2005 / 054479); event COT203 (cotton, insect control, not deposited, described in WO 2005 / 054480); ); event DAS21606-3 / 1606 (soybean, herbicide resistance, deposited as PTA-11028, described in WO 2012 / 033794), event DAS40278 (maize, herbicide resistance, deposited as ATCC PTA-10244, described in WO 2011 / 022469);Event DAS-44406-6 / pDAB8264.44.06.1 (soybean, herbicide resistance, deposited as PTA-11336, described in WO 2012 / 075426), Event DAS-14536-7 / pDAB8291.45.36.2 (soybean, herbicide resistance, deposited as PTA-11335, described in WO 2012 / 075429), Event DAS-59122-7 (maize, insect control - herbicide resistance, ATCC PTA11384, described in U.S. Patent Publication No. 2006 / 070139); event DAS-59132 (corn, insect control - herbicide resistance, not deposited, described in WO 2009 / 100188); event DAS68416 (soybean, herbicide resistance, deposited as ATCC PTA-10442, described in WO 2011 / 066384 or WO 2011 / 066360); event DP-098140-6 (corn, herbicide resistance, ATCC PTA-8296, described in U.S. Patent Application Publication No. 2009-137395 or WO 08 / 112019); Event DP-305423-1 (soybean, quality traits, not deposited, described in U.S. Patent Application Publication No. 2008-312082 or WO 2008 / 054747); Event DP-32138-1 (maize, hybridization system, deposited as ATCC PTA-9158, described in U.S. Patent Application Publication No. 2009 / 0210970 or WO 2009 / 103049); Event DP-356043-5 (soybean, herbicide tolerance, deposited in ATCC PTA-8287, described in U.S. Patent Application Publication No. 2010 / 0184079 or WO 2008 / 002872); event EE-I (eggplant, insect control, not deposited, described in WO 07 / 091277); event Fil17 (corn, herbicide resistance, deposited as ATCC209031, described in U.S. Patent Application Publication No. 2006-059581 or WO 98 / 044140);Event FG72 (soybean, herbicide resistance, deposited as PTA-11041, described in WO 2011 / 063413), event GA21 (maize, herbicide resistance, deposited as ATCC209033, described in U.S. Patent Application Publication No. 2005-086719 or WO 98 / 044140); event GG25 (maize, herbicide resistance, deposited as ATCC209032, described in U.S. Patent Application Publication No. 2005 / 188434 or WO 98 / 044140); event GHB119 (cotton, insect control-herbicide resistance, deposited as ATCC PTA-8398, described in WO 2008 / 151780); event GHB614 (cotton, herbicide resistance, deposited as ATCC PTA-6878, described in U.S. Patent Application Publication No. 2010-050282 or WO 2007 / 017186); event GJ11 (corn, herbicide resistant, described in U.S. Patent Application Publication No. 2005 / 188434 or WO 98 / 044140, deposited as ATCC209030); event GM RZ13 (sugar beet, virus resistance, deposited as NCIMB-41601, described in WO 2010 / 076212); event H7-l (sugar beet, herbicide resistance, deposited as NCIMB41158 or NCIMB41159, described in U.S. Patent Application Publication No. 2004 / 172669 or WO 2004 / 074492); event JOPLINl (wheat, disease resistance, not deposited, U.S. Patent Application Publication No. 2008 / 0640 32); event LL27 (soybean, herbicide resistance, deposited as NCIMB41658, described in WO 2006 / 108674 or US 2008-320616); event LL55 (soybean, herbicide resistance, deposited as NCIMB41660, described in WO 2006 / 108675 or US 2008-196127); event LLcotton25 (cotton, herbicide resistance, deposited as ATCC PTA-3343, described in WO 2003 / 013224 or US 2003 / 097687);Event LLRICE06 (rice, herbicide tolerance, deposited as ATCC203353, described in U.S. Pat. No. 6,468,747 or WO 2000 / 026345); event LLRice62 (rice, herbicide tolerance, deposited as ATCC203352, described in WO 2000 / 026345), event LLRICE601 (rice, herbicide tolerance, deposited as ATCC PTA-2600, described in U.S. Pat. Appl. Pub. No. 2008 / 2289060 or WO 2000 / 026356); event LY038 (maize, quality traits, deposited as ATCC PTA-5623, described in U.S. Patent Application Publication No. 2007 / 028322 or WO 2005 / 061720); event MIR162 (corn, insect control, deposited as PTA-8166, described in U.S. Patent Application Publication No. 2009 / 300784 or WO 2007 / 142840); event MIR604 (corn, insect control, not deposited, described in U.S. Patent Application Publication No. 2008-167456 or WO 2005 / 103301); event MON15985 (cotton, insect control, ATCC PTA-2516, described in U.S. Patent Application Publication No. 2004 / 250317 or WO 2002 / 100163); event MON810 (corn, insect control, not deposited, described in U.S. Patent Application Publication No. 2002 / 102582); event MON863 (corn, insect control, deposited as ATCC PTA-2605, described in WO 2004 / 011601 or U.S. Patent Application Publication No. 2006 / 095986); event MON87427 (corn, pollination control, deposited as ATCC PTA-7899, described in WO 2011 / 062904); event MON87460 (corn, stress tolerance, deposited as ATCC PTA-8910, described in WO 2009 / 111263 or U.S. Patent Application Publication No. 2011 / 0138504);Event MON87701 (soybean, insect control, deposited as ATCC PTA-8194, described in U.S. Patent Application Publication No. 2009 / 130071 or WO 2009 / 064652); Event MON87705 (soybean, quality traits - herbicide tolerance, deposited as ATCC PTA-9241, described in U.S. Patent Application Publication No. 2010 / 0080887 or WO 2010 / 037016); Event MON87708 (soybean, herbicide tolerance, deposited as ATCC PTA-9670, described in WO 2011 / 034704); Event MON87712 (soybean, yield, deposited as PTA-10296, described in WO 2012 / 051199), Event MON87754 (soybean, quality traits, deposited as ATCC PTA-9385, described in WO 2010 / 024976); event MON87769 (soybean, quality traits, deposited as ATCC PTA-8911, described in U.S. Patent Application Publication No. 2011 / 0067141 or International; Publication No. 2009 / 102873); event MON88017 (corn, insect control-herbicide resistance, deposited as ATCC PTA-5582, described in U.S. Patent Application Publication No. 2008 / 028482 or WO 2005 / 059103); event MON88913 (cotton, herbicide resistance, deposited as ATCC PTA-5582, described in U.S. Patent Application Publication No. 2009 / 102873); PTA-4854, described in WO 2004 / 072235 or U.S. Patent Application Publication No. 2006 / 059590); event MON88302 (rapeseed, herbicide resistance, deposited as PTA-10955, described in WO 2011 / 153186), event MON88701 (cotton, herbicide resistance, deposited as PTA-11754, described in WO 2012 / 134808), event MON89034 (corn, insect control, deposited as ATCC PTA-7455, described in WO 07 / 140256 or U.S. Patent Application Publication No. 2008 / 260932); event MON89788 (soybean, herbicide resistance, deposited as ATCC PTA-7455, described in WO 07 / 140256 or U.S. Patent Application Publication No. 2008 / 260932); PTA-6708, described in U.S. Patent Application Publication No. 2006 / 282915 or WO 2006 / 130436); event MSl 1 (rapeseed, pollination control-herbicide resistance, deposited as ATCC PTA-850 or PTA-2485, described in WO 2001 / 031042); event MS8 (rapeseed, pollination control-herbicide resistance, deposited as ATCC PTA-730, described in WO 2001 / 041558 or U.S. Patent Application Publication No. 2003 / 188347); event NK603 (corn, herbicide resistance, deposited as ATCC PTA-2478, described in U.S. Patent Application Publication No. 2007 / 292854); event PE-7 (rice, insect control, not deposited, described in WO 2008 / 114282); event RF3 (rapeseed, pollination control - herbicide resistance, deposited as ATCC PTA-730, described in WO 2001 / 041558 or U.S. Patent Application Publication No. 2003 / 188347); event RT73 (rapeseed, herbicide resistance, not deposited,Event SYHT0H2 / SYN-000H2-5 (soybean, herbicide resistant, deposited as PTA-11226, described in WO 2012 / 082548), Event T227-1 (sugar beet, herbicide resistant, not deposited, described in WO 2002 / 44407 or US 2009 / 265817); Event T25 (corn, herbicide resistant, not deposited, described in US 2001 / 029014 or WO 2001 / 051654); Event T304-40 (cotton, insect control - herbicide resistant, ATCC PTA-8171, described in U.S. Patent Application Publication No. 2010-077501 or WO 2008 / 122406); Event T342-142 (cotton, insect control, not deposited, described in WO 2006 / 128568); Event TC1507 (corn, insect control - herbicide resistance, not deposited, described in U.S. Patent Application Publication No. 2005 / 039226 or WO 2004 / 099447); Event VIP1034 (corn, insect control - herbicide resistance, ATCC Event 32316 (maize, insect control - herbicide resistance, deposited as PTA-11507, described in WO 2011 / 084632), Event 4114 (maize, insect control - herbicide resistance, deposited as PTA-11506, described in WO 2011 / 084621), Event EE-GM3 / FG72 (soybean, herbicide resistance, ATCC Accession No. PTA-11041) Event DAS-68416-4 (soybean, herbicide tolerance, ATCC Accession No. PTA-10442, WO 2011 / 066360(A1)), Event DAS-68416-4 (soybean, herbicide tolerance, ATCC Accession No. PTA-10442, WO 2011 / 066384(A1)), Event DP-040416-8 (maize, insect control,ATCC Accession No. PTA-11508, WO 2011 / 075593(A1)), Event DP-043A47-3 (Maize, insect control, ATCC Accession No. PTA-11509, WO 2011 / 075595(A1)), Event DP-004114-3 (Maize, insect control, ATCC Accession No. PTA-11506, WO 2011 / 084621(A1)), Event DP-032316-8 (Maize, insect control, ATCC Accession No. PTA-11507, WO 2011 / 084632(A1)) , event MON-88302-9 (rapeseed, herbicide resistance, ATCC accession no. PTA10955, WO 2011 / 153186(A1)), event DAS-21606-3 (soybean, herbicide resistance, ATCC accession no. PTA-11028, WO 2012 / 033794(A2)), event MON-87712-4 (soybean, quality traits, ATCC accession no. PTA-10296, WO 2012 / 051199(A2)), event DAS-44406-6 (soybean, stacked herbicide resistance, ATCC accession no. No. PTA-11336, WO 2012 / 075426(A1)), event DAS-14536-7 (soybean, stacked herbicide resistance, ATCC Accession No. PTA-11335, WO 2012 / 075429(A1)), event SYN-000H2-5 (soybean, herbicide resistance, ATCC Accession No. PTA-11226, WO 2012 / 082548(A2)), event DP-061061-7 (rapeseed, herbicide resistance, no accession number available, WO 2012 / 071039(A1)), event Event DP-073496-4 (rapeseed, herbicide resistance, no accession number available, U.S. Patent Application Publication No. 2012 / 131692), Event 8264.44.06.1 (soybean, stacked herbicide resistance, accession number PTA-11336, WO 2012 / 075426(A2)), Event 8291.45.36.2 (soybean, stacked herbicide resistance, accession number PTA-11335, WO 2012 / 075429(A2)), Event SYHT0H2 (soybean, ATCC Accession No. PTA-11226,WO 2012 / 082548(A2)), event MON88701 (cotton, ATCC Accession No. PTA-11754, WO 2012 / 134808(A1)), event KK179-2 (alfalfa, ATCC Accession No. PTA-11833, WO 2013 / 003558(A1)), event pDAB8264.42.32.1 (soybean, stacked herbicide resistance, ATCC Accession No. PTA-11993, WO 2013 / 010094(A1)), event MZDT09Y (maize, ATCC Accession No. PTA-13025, WO 2013 / 012775(A1).

[0157] Additionally, lists of such transgenic events are provided by the United States Department of Agriculture (USDA) Animal and Plant Inspection Service (APHIS) and can be found on their website on the World Wide Web at aphis.usda.gov. For the purposes of this application, the status of such lists as they exist or were as of the filing date of this application is relevant.

[0158] The genes / events that confer the desired traits in question may be present in combination with each other in transgenic plants. Examples of transgenic plants that may be mentioned are important crop plants such as cereals (wheat, rice, triticale, barley, rye, oats), corn, soybean, potato, sugar beet, sugarcane, tomato, pea and other types of vegetables, cotton, tobacco, rapeseed, as well as fruit plants (with fruits that are apples, pears, citrus fruits and grapes), with corn, soybean, wheat, rice, potato, cotton, sugarcane, tobacco and rapeseed being of particular importance. Traits that are particularly emphasized are the increased resistance of the plants to insects, spiders, nematodes and slugs and snails, as well as the increased resistance of the plants to one or more herbicides.

[0159] Commercially available examples of such plants, plant parts or plant seeds that may be preferably treated according to the invention include commercially available products such as plant seeds sold or distributed under the trade names GENUITY®, DROUGHTGARD®, SMARTSTAX®, RIB COMPLETE®, ROUNDUP READY®, VT DOUBLE PRO®, VT TRIPLE PRO®, BOLLGARD II®, ROUNDUP READY 2 YIELD®, YIELDGARD®, ROUNDUP READY® 2 XTEND™, INTACTA RR2 PRO®, VISTIVE GOLD® and / or XTENDFLEX™.

[0160] pathogen Non-limiting examples of fungal disease pathogens that can be treated according to the present invention include: Diseases caused by powdery mildew pathogens, for example Blumeria spp., for example Blumeria graminis; Podosphaera spp., for example Podosphaera leucotricha; Sphaerotheca spp., for example Sphaerotheca fuliginea; Uncinula spp., for example Erysiphe necator; Rust pathogens, for example Gymnosporangium spp., for example Gymnosporangium sabinae; Hemileia spp., for example Hemileia vastatrix; Phakopsora spp., for example Phakopsora pachyrhizi, Phakopsora meibomiae or Phakopsora euvitis; Puccinia spp., for example Puccinia recondita, Puccinia graminis or Puccinia striiformis; striiformis);diseases caused by Uromyces species, e.g. Uromyces appendiculatus; Pathogens from the group of the oomycetes, for example Albugo species, for example Albugo candida; Bremia species, for example Bremia lactucae; Peronospora species, for example Peronospora pisi or P. brassicae; Phytophthora species, for example Phytophthora infestans; Plasmopara species, for example Plasmopara viticola; Pseudoperonospora species, for example Pseudoperonospora humilis; humuli or Pseudoperonospora cubensis; diseases caused by Pythium species, e.g. Pythium ultimum; For example, Alternaria species, such as Alternaria solani; Cercospora species, such as Cercospora beticola; Cladiosporium species, such as Cladiosporium cucumerinum; Cochliobolus species, such as Cochliobolus sativus (conidiophores: Drechslera, synonym: Helminthosporium) or Cochliobolus miyabeanus; Colletotrichum species, such as Colletotrichum lindemtanium. lindemuthanium; Corynespora species, for example, Corynespora cassiicola; Cycloconium species, for example, Cycloconium oleaginum; Diaporthe species, for example, Diaporthe citri; Elsinoe species, for example, Elsinoe fawcettii; Gloeosporium species, for example, Gloeosporium laeticolor; Glomerella species, for example, Glomerella cingulata; Guignardia species, for example, Guignardia bidwelli bidwelli); Leptosphaeria species, such as Leptosphaeria maculans; Magnaporthe species, such as Magnaporthe grisea;Microdochium species, such as Microdochium nivale; Mycosphaerella species, such as Zymoseptoria tritici (syn. Mycosphaerella graminicola), Mycosphaerella arachidicola or Mycosphaerella fijiensis; Phaeosphaeria species, such as Phaeosphaeria nodorum; Pyrenophora species, such as Pyrenophora teres or Pyrenophora tritici repentis. repentis; Ramularia species, for example, Ramularia collo-cygni or Ramularia areola; Rhynchosporium species, for example, Rhynchosporium secalis; Septoria species, for example, Septoria apii or Septoria lycopersici; Stagonospora species, for example, Stagonospora nodorum; Typhula species, for example, Typhula incarnata; Venturia species, for example, Venturia inaecharis. Leaf blight and wilt caused by Bacillus inaequalis; For example, Corticium species, such as Corticium graminearum; Fusarium species, such as Fusarium oxysporum; Gaeumannomyces species, such as Gaeumannomyces graminis; Plasmodiophora species, such as Plasmodiophora brassicae; Rhizoctonia species, such as Rhizoctonia solani; Sarocladium species, such as Sarocladium oryzae; Sclerotium species, such as Sclerotium oryzae. oryzae; Tapesia spp., e.g., Tapesia acuformis; Root and stem diseases caused by Thielaviopsis spp., e.g., Thielaviopsis basicola; For example, Alternaria species, such as Alternaria spp.; Aspergillus species, such as Aspergillus flavus; Cladosporium species, such as Cladosporium cladosporioides; Claviceps species, such as Claviceps purpurea; Fusarium species, such as Fusarium culmorum; Gibberella species, such as Gibberella zeae; Monographella species, such as Monographella nivalis. nivalis); diseases of ears and panicles (including corn cobs) caused by Stagnospora species, e.g., Stagnospora nodorum; diseases caused by smut fungi, for example Sphacelotheca spp., for example Sphacelotheca reiliana; Tilletia spp., for example Tilletia caries or Tilletia controversa; Urocystis spp., for example Urocystis occulta; Ustilago spp., for example Ustilago nuda; For example, Aspergillus species, such as Aspergillus flavus; Botrytis species, such as Botrytis cinerea; Monilinia species, such as Monilinia laxa; Penicillium species, such as Penicillium expansum or Penicillium purpurogenum; Rhizopus species, such as Rhizopus stolonifer; Sclerotinia species, such as Sclerotinia sclerotiorum. sclerotiorum); fruit rot caused by Verticilium species, e.g. Verticilium alboatrum; For example, Alternaria species, such as Alternaria brassicicola; Aphanomyces species, such as Aphanomyces euteiches; Ascochyta species, such as Ascochyta lentis; Aspergillus species, such as Aspergillus flavus; Cladosporium species, such as Cladosporium herbarum; Cochliobolus species, such as Cochliobolus sativus (conidiophores: Drechslera, bipolar Synonyms: Helminthosporium; Colletotrichum spp., for example, Colletotrichum coccodes; Fusarium spp., for example, Fusarium culmorum; Gibberella spp., for example, Gibberella zeae; Macrophomina spp., for example, Macrophomina phaseolina; Microdochium spp., for example, Microdochium nivale; Monographella spp., for example, Monographella nivalis; Penicillium spp., for example, Penicillium expansum expansum);Phoma species, e.g., Phoma lingam;Phomopsis species, e.g., Phomopsis sojae;Phytophthora species, for example, Phytophthora cactorum; Pyrenophora species, for example, Pyrenophora graminea; Pyricularia species, for example, Pyricularia oryzae; Pythium species, for example, Pythium ultimum; Rhizoctonia species, for example, Rhizoctonia solani; Rhizopus species, for example, Rhizopus oryzae; Sclerotium species, for example, Sclerotium rolfsii rolfsii); Septoria spp., for example, Septoria nodorum; Typhula spp., for example, Typhula incarnata; Verticillium spp., for example, Verticillium dahliae, causing seed and soil-borne rot and leaf spot, as well as seedling diseases; For example, cancer, galls and witches' broom caused by Nectria species, e.g. Nectria galligena; For example, Verticillium species, such as Verticillium longisporum; Fusarium species, such as Fusarium oxysporum, causing leaf spot; Deformations of leaves, flowers and fruits caused by, for example, Exobasidium species, e.g., Exobasidium vexans; Taphrina species, e.g., Taphrina deformans; For example, degenerative diseases in woody plants caused by Esca species, such as Phaeomoniella chlamydospora, Phaeoacremonium aleophilum or Fomitiporia mediterranea; Ganoderma species, such as Ganoderma boninense; tuber diseases caused by, for example, Rhizoctonia species, e.g., Rhizoctonia solani; Helminthosporium species, e.g., Helminthosporium solani; Bacterial pathogens, such as Xanthomonas species, for example, Xanthomonas campestris pv. oryzae; Pseudomonas species, for example, Pseudomonas syringae pv. lachrymans; Erwinia species, for example, Erwinia amylovora; Liberibacter species, for example, Liberibacter asiaticus; Xylella species, for example, Xylella fastidiosa; Ralstonia species, for example, Ralstonia solanacearum; solanacearum; Dickeya spp., e.g. Dickeya solani; Clavibacter spp., e.g. Clavibacter michiganensis; Streptomyces spp., e.g. Streptomyces scabies, Examples include:

[0161] Soybean Diseases: For example, Alternaria leaf spot (Alternaria spec. atrans tenuissima), anthracnose (Colletotrichum gloeosporoides dematium var.truncatum), brown spot (Septoria glycines), Cercospora leaf spot and leaf blight (Cercospora kikuchii), Choanephora leaf blight (Choanephora infundibulifera trispora (syn.)), Dactuliophora leaf spot (Dactuliophora glycines), downy mildew (Peronospora manshurica), Drexlera canker (Drechslera glycini), leaf spot (Cercospora sojina) sojina), Leptosphaerulina leaf spot (Leptosphaerulina trifolii), Phyllosticta leaf spot (Phyllosticta sojaecola), pod and stem blight (Phomopsis sojae), powdery mildew (Microsphaera diffusa), Pyrenochaeta leaf spot (Pyrenochaeta glycines), Rhizoctonia aerial, leaf and spider blight (Rhizoctonia solani), rust (Phakopsora patilis), Fungal diseases of leaves, stems, pods and seeds caused by fungal diseases such as lichen moth (Phakopsora pachyrhizi, Phakopsora meibomiae, Phakopsora euvitis), scab (Sphaceloma glycines), stemphyllium leaf blight (Stemphylium botryosum), sudden death syndrome (Fusarium virguliforme), ring spot (Corynespora cassiicola).

[0162] For example, microscopic sclerotinia disease (Calonectria crotalariae), charcoal rot (Macrophomina phaseolina), red mold or wilt, root rot, and pod and neck rot (Fusarium oxysporum, Fusarium orthoceras, Fusarium semitectum, Fusarium equiseti), Mycoleptodiscus root rot (Mycoleptodiscus terrestris), Neocosmospora (Neocosmospora vasinfecta), pod and stem blight (Diaporthe phaseolorum), and other diseases. phaseolorum), branch dieback (Diaporthe phaseolorum var. caulivora), stem rot (Phytophthora megasperma), leaf drop (Phialophora gregata), Pythium rot (Pythium aphanidermatum, Pythium irregulare, Pythium debaryanum, Pythium myriotylum, Pythium ultimum), Rhizoctonia root rot, stem rot, and damping off (Rhizoctonia solani) solani), Sclerotinia stem rot (Sclerotinia sclerotiorum), Sclerotinia southern blight (Sclerotinia rolfsii), and fungal diseases of the roots and culm base caused by Thielaviopsis root rot (Thielaviopsis basicola).

[0163] Mycotoxins In addition, the compound combinations and compositions of the present invention may reduce the mycotoxin content in harvested materials and foodstuffs and feeds produced therefrom. Mycotoxins include, but are not limited to, those produced by the following fungi, such as F. acuminatum, F. asiaticum, F. avenaceum, F. crookwellense, F. culmorum, F. graminearum (Gibberella zeae), and the like. zeae), F. equiseti, F. fujikoroi, F. musarum, F. oxysporum, F. proliferatum, F. poae, F. pseudograminearum, F. sambucinum, F. sci Fusarium species such as F. rpi, F. semitectum, F. solani, F. sporotrichoides, F. langsethiae, F. subglutinans, F. tricinctum, and F. verticillioides. spec., and Aspergillus species such as A. flavus, A. parasiticus, A. nomius, A. ochraceus, A. clavatus, A. terreus, A. versicolor, P. verrucosum, P. viridicatum, P. citrinum, P. expansum, P. claviforme, P. roqueforti, P.Deoxynivalenol (DON), nivalenol, 15-Ac-DON, 3-Ac-DON, T2- and HT2-toxins, fumonisins, zearalenone, moniliformin, fusarin, diacetoxyscirpenol (DAS), beauvericin, enniatin, fusaroproliferin, fusarenol, ochratoxin, patulin, ergot alkaloids and aflatoxins which can be produced by Penicillium species (P. Penicillium spec.) such as C. roqueforti), Claviceps species (C. purpurea, C. fusiformis, C. paspali, C. africana), Stachybotrys species (Stachybotrys spec.) and others.

[0164] material protection The compound combinations according to the invention and compositions comprising such combinations may be used in the protection of industrial materials for the protection of industrial materials against attack and degradation by phytopathogenic fungi.

[0165] In addition, compound combinations according to the present invention and compositions comprising such combinations may be used as antifouling compositions, either alone or in combination with other active ingredients.

[0166] In this context, industrial materials are understood to mean inanimate materials produced for use in industry. For example, industrial materials to be protected from microbial deterioration or decomposition may be adhesives, glues, paper, wallpaper and cardboard, textiles, carpets, leather, wood, textiles and tissues, paints and plastic products, cooling lubricants and other materials that can be infected or decomposed by microorganisms. Parts of manufacturing plants and buildings that can be damaged by microbial growth, such as cooling water circuits, cooling and heating systems and ventilation and air conditioning units, may also be mentioned within the scope of materials to be protected. Industrial materials within the scope of the present invention preferably include adhesives, sizes, paper and cardboard, leather, wood, paints, cooling lubricants and heat transfer liquids, more preferably wood.

[0167] The compound combinations and compositions of the present invention may prevent harmful effects such as spoilage, decay, discolouration, bleaching or mould growth.

[0168] In the treatment of wood, the compound combinations and compositions of the present invention may be used against fungal diseases which tend to grow on or within the material.

[0169] Materials refer to all types of wood species and all types of processed products of this wood for construction purposes, such as solid wood, high density wood, laminated wood, and veneer plywood.In addition, the compounds and compositions of the present invention may be used to protect objects in contact with salt water or fresh water, in particular grain, screens, netting, buildings, mooring rigging and communication systems, from fouling.

[0170] The compound combinations and compositions of the present invention may be used to protect stored goods. A stored product is understood to mean a natural material of plant or animal origin or a processed product of natural origin for which long-term protection is desired. Stored products of plant origin, such as plants or plant parts such as stems, leaves, tubers, seeds, fruits, grains, etc., may be protected freshly harvested or after processing by (pre)drying, moistening, pulverizing, grinding, pressing or roasting. Stored products also include materials both in the form of raw products, such as building materials, electric poles and electric barriers, or in the form of final products, such as furniture. Stored products of animal origin are, for example, leather, tanned leather, furs and hairs. The compound combinations and compositions of the present invention may prevent harmful effects, such as decay, rotting, discolouration, bleaching or mould formation.

[0171] Microorganisms capable of decomposing or deteriorating industrial materials include, for example, bacteria, fungi, yeasts, algae and slime organisms.The compound combinations and compositions of the present invention preferably have activity against fungi, particularly molds, wood-staining and wood-decomposing fungi (Ascomycetes, Basidiomycetes, Deuteromycetes and Zygomycetes), as well as slime organisms and algae. Examples include microorganisms from the following genera: Alternaria, such as Alternaria tenuis; Aspergillus, such as Aspergillus niger; Chaetomium, such as Chaetomium globosum; Coniophora, such as Coniophora puetana; Lentinus, such as Lentinus tigrinus; Penicillium, such as Penicillium glaucum; Polyporus, such as Polyporus versicolor; Aureobasidium pullulans. Aureobasidium spp., such as Aureobasidium pullulans; Sclerophoma spp., such as Sclerophoma pityophila; Trichoderma spp., such as Trichoderma viride; Ophiostoma spp., Ceratocystis spp., Humicola spp., Petriella spp., Trichurus spp., Coriolus spp., Gloeophyllum spp., Pleurotus spp.), Poria spp., Serpula spp. and Tyromyces spp., Cladosporium spp., Paecilomyces spp., Mucor spp., Escherichia spp., such as Escherichia coli; Pseudomonas spp., such as Pseudomonas aeruginosa; Staphylococcus spp., such as Staphylococcus aureus, Candida spp. and Saccharomyces cerevisiae. Saccharomyces spp. such as Saccharomyces cerevisae.

[0172] Seed treatment The compound combinations and compositions of the present invention may be used to protect seeds from unwanted microorganisms, such as phytopathogenic microorganisms, for example, phytopathogenic fungi or phytopathogenic oomycetes. As used herein, the term seeds includes dormant seeds, primed seeds, pre-germinated seeds and seeds with roots and leaves sprouted.

[0173] The present invention therefore also relates to a method for protecting seeds from undesirable microorganisms comprising a step of treating the seeds with a compound combination or composition according to the invention, said seeds may be treated simultaneously, separately or sequentially with compounds (A) and (B).

[0174] The treatment of seeds with the compound combination or composition of the present invention not only protects the seeds from phytopathogenic microorganisms, but also protects the germinated seeds, germinated seedlings and plants after germination from the treated seeds.Therefore, the present invention also relates to a method for protecting seeds, germinated seeds and germinated seedlings.

[0175] Seed treatment may be carried out before, at or immediately after sowing.

[0176] When seed treatment is carried out before sowing (for example, so-called on-seed spraying), seed treatment can be carried out as follows: seeds are placed in a mixer together with a desired amount of the compound combination or composition of the present invention, and the seeds and the compound combination or composition of the present invention are mixed until they are uniformly distributed on the seeds.The seeds can then be dried if necessary.

[0177] The present invention also relates to seeds which are coated with the compound combinations or compositions of the present invention.

[0178] Preferably, the seeds are treated in a state that is sufficiently stable so that damage does not occur during the treatment process. In general, the seeds can be treated at any time between harvesting and immediately after sowing. It is customary to use seeds that are separated from the plant and free of cobs, husks, stalks, coats, hairs or fruit flesh. For example, it is possible to use seeds that are harvested, washed and dried to a moisture content of less than 15% by weight. Alternatively, it is also possible to use seeds that are dried, for example treated with water and then dried again, or seeds that are immediately after priming, or seeds that are stored under priming conditions or pre-germinated seeds, or seeds that are sown on trays, tapes or papers in seedbeds.

[0179] The amount of the compound combination or composition of the present invention that is sprayed on seeds is usually such that the germination of the seeds is not impaired or the resulting plants are not damaged.This must be guaranteed, especially when the compounds contained in the compound combination of the present invention show phytotoxicity at a certain application rate.When determining the amount of the compound combination of the present invention to be sprayed on seeds, the specific phenotype of the transgenic plant should be taken into account in order to achieve optimal seed and germination plant protection with the minimum amount of compound used.

[0180] The compounds included in the compound combination of the present invention can be directly sprayed on seeds, i.e., without other components and without dilution. They can be sprayed simultaneously, separately or sequentially. The composition including the compound included in the compound combination of the present invention, such as the composition of the present invention, can be sprayed on seeds.

[0181] The compound combination and composition of the present invention are suitable for protecting the seeds of any plant variety.Preferred seeds are those of cereals (wheat, barley, rye, millet, triticale and oats), rapeseed, corn, cotton, soybean, rice, potato, sunflower, kidney bean, coffee, pea, beet (such as sugar beet and fodder beet), peanut, vegetable (such as tomato, cucumber, onion and lettuce), turf and ornamental plants.More preferred are the seeds of wheat, soybean, rapeseed, corn and rice.

[0182] The compound combinations and compositions of the present invention may be used to treat transgenic seeds, particularly the seeds of plants that can express a polypeptide or protein that acts against pests, herbicide damage or abiotic stress, thereby enhancing the protective effect.The seeds of plants that can express a polypeptide or protein that acts against pests, herbicide damage or abiotic stress may contain at least one heterologous gene that allows the expression of said polypeptide or protein.The heterologous gene in transgenic seeds may originate from a microorganism of, for example, Bacillus species, Rhizobium species, Pseudomonas species, Serratia species, Trichoderma species, Clavibacter species, Glomus species or Gliocladium species. These heterologous genes preferably originate from Bacillus species, in which case the gene product is effective against the European corn borer and / or the Western corn rootworm. Particularly preferably, the heterologous genes originate from Bacillus thuringiensis.

[0183] Spraying The compound combinations of the present invention can be applied as such or in the form of, for example, ready-to-use solutions, emulsifiable concentrates, water- or oil-based suspensions, dusts, wettable powders, pastes, water-soluble powders, dusts, soluble granules, granules for general application, suspoemulsion concentrates, natural products impregnated with the compound combinations of the present invention, synthetic products impregnated with the compound combinations of the present invention, fertilizers or microencapsulated in polymeric substances.

[0184] For example, application is carried out in a conventional manner by irrigation, spraying, misting, general application, dusting, foam application, or spreading-on. It is also possible to utilize the compound combination of the present invention by a very low volume method by drip irrigation system or drench application, to apply the compound combination of the present invention to the infallo, or to inject the compound combination of the present invention into the stem or trunk of the soil. It is also possible to apply the compound combination of the present invention by wound seal, painting, or other wound dressing. The effective and plant-compatible amount of the compound combination of the present invention applied to the plant, plant part, fruit, or soil depends on various factors such as the compound / composition used, the treatment target (plant, plant part, fruit, seed, or soil), the type of treatment (dusting, spraying, seed dressing), the purpose of treatment (healing and protection), the type of microorganism, the growth stage of the microorganism, the sensitivity of the microorganism, the crop growth stage, and environmental conditions.

[0185] When the compound combinations of the invention are used as antifungal agents, the application rates can vary within a relatively wide range, depending on the type of application. For the treatment of plant parts such as leaves, the application rates can range from 0.1 to 10000 g / ha, preferably from 10 to 1000 g / ha, more preferably from 50 to 300 g / ha (in the case of application by irrigation or drip irrigation, it is still possible to reduce the application rates, especially when using inert materials such as rock wool or perlite). For the treatment of seeds, the application rates can range from 0.1 to 200 g / 100 kg of seeds, preferably from 1 to 150 g / 100 kg of seeds, more preferably from 2.5 to 25 g / 100 kg of seeds, even more preferably from 2.5 to 12.5 g / 100 kg of seeds. For the treatment of soil, the application rates can range from 0.1 to 10000 g / ha, preferably from 1 to 5000 g / ha. The application rates outlined represent the total application rates of compounds (A) and (B) present in the compound combination of the present invention.

[0186] These application rates are merely examples and are not intended to limit the scope of the invention.

[0187] The compound combination of the present invention can be used in combination with models embedded in computer programs for, for example, site-specific crop management, satellite farming, precision farming or precision agriculture. Such models use data from various sources, such as soil, weather, crops (e.g., type, growth stage, plant health), weeds (e.g., type, growth stage), disease, pests, nutrients, water, moisture, biomass, satellite data, yield, etc., to support site-specific management of agricultural land with the aim of optimizing profitability, sustainability and protection of the environment. In particular, such models can help optimize agronomic decisions, control the precision of pesticide spraying, and record the work carried out.

[0188] As an example, a compound of the present invention can be sprayed on a crop plant according to an appropriate dosage when the model models the development of a fungal disease and calculates that a threshold has been reached at which it is recommended to spray the compound of the present invention on the crop plant.

[0189] Commercially available systems that include agronomic models include, for example, FieldScripts™ from The Climate Corporation, Xarvio™ from BASF, and AGLogic™ from John Deere.

[0190] The compounds of the present invention can also be used in combination with smart spraying devices, such as spot spraying or precision spraying devices that are combined or housed in agricultural vehicles, such as tractors, robots, helicopters, airplanes, unmanned aerial vehicles (UAVs) such as drones. Such devices usually include an input sensor (such as a camera) and a processing unit that is configured to analyze input data and provide a decision based on the analysis of the input data to specifically and accurately spray the compounds of the present invention on crop plants (respectively, weeds). The use of such smart spraying devices also usually requires a location system (such as a GPS receiver) to locate recorded data and guide or control the agricultural vehicle; a geographic information system (GIS) to represent information on a clear map, and a suitable agricultural vehicle to perform the required agricultural operations, such as spraying.

[0191] In one example, fungal diseases can be detected from images acquired by a camera. In one example, fungal diseases can be identified and / or classified based on the images. Such identification and classification can use image processing algorithms. Such image processing algorithms can utilize machine learning algorithms such as trained neural networks, decision trees, and can utilize artificial intelligence algorithms. In this way, the compounds described herein can be sprayed only where needed.

[0192] The present invention will be illustrated by the following examples, but the present invention is not limited to these examples. EXAMPLES

[0193] The high antifungal activity of the active compound combinations according to the invention is evident from the following examples: Although the individual active compounds show weaknesses in terms of antifungal activity, the combinations have activity that goes beyond a simple addition of activity.

[0194] A synergistic effect of antifungal agents exists whenever the antifungal activity of an active compound combination exceeds the sum of the activities of the active compounds when applied individually. The expected activity for a given combination of two active compounds can be calculated as follows (Colby, SR, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds 1967, 15, 20-22): X is the efficacy when active compound A is applied at a rate of m ppm (or g / ha), Y is the efficacy when active compound B is applied at a rate of n ppm (or g / ha), and E is the efficacy when active compounds A and B are applied at application rates of m and n ppm (or g / ha), respectively;

[0195] E = X + Y - [(X Y) / 100]

[0196] For ternary mixtures, the Colby equation is: X is the efficacy when active compound A is applied at a rate of m ppm (or g / ha), Y is the efficacy when active compound B is applied at a rate of n ppm (or g / ha), Z is the efficacy when the active compound C is applied at a rate of o ppm (or g / ha), and E is the efficacy when active compounds A, B and C are applied at application rates of m, n and O ppm (or g / ha), respectively;

[0197] E=X+Y+Z-[(X·Y) / 100]-[(X·Z) / 100]-[(Y·Z) / 100]+[(X·Y·Z) / 100·100]

[0198] The degree of efficacy expressed as a percentage is given, where 0% means efficacy consistent with the control, whereas 100% efficacy means that no disease was observed.

[0199] If the actual antifungal activity exceeds the calculated value, the activity of the combination is superadditive, i.e., synergistic effects exist. In this case, the actual observed efficacy must be greater than the expected efficacy (E) value calculated from the above formula.

[0200] A further method for demonstrating synergistic effects is the Tammes method (see "Isoboles, a graphic representation of synergism in pesticides" in Neth. J. Plant Path., 1964, 70, 73-80).

[0201] Example A: In vitro testing with fungal microorganisms The wells of a 96-well microtiter plate are filled with 10 μl of a preparation of the test compound or compound combination in methanol + emulsifier alkylaryl-polyglycol-ether. After this, the solvent is evaporated in a hood. In the next step, each well receives 100 μl of liquid potato dextrose medium amended with a spore or mycelium suspension of the test fungus at the appropriate concentration.

[0202] Extinction in all wells is measured at a wavelength of 620 nm using a photometer.

[0203] The microtiter plates are incubated at 20° C. and 85% relative humidity. 3-5 days after spraying, growth inhibition is determined again using a photometer. Efficacy is calculated with respect to the untreated control, 0% efficacy means that fungal growth is as high as in the untreated control, whereas 100% efficacy means that no fungal growth is measured.

[0204] The table below clearly shows that the observed activity of the active compound combination according to the invention is greater than the calculated activity, ie there is a synergistic effect.

[0205] [Table 1]

[0206]

Table 2

[0207]

Table 3

[0208]

Table 4

[0209]

Table 5

[0210]

Table 6

Claims

1. An active compound combination, said active compound combination comprising: (A) as compound (A), methyl 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3-(1,2,4-triazol-1-yl)propanoate; (B) As the compound (B), (3.017) methallyl picoxamide 10. An active compound combination comprising:

2. 2. The active compound combination according to claim 1, wherein the weight ratio of compound (A) to compound (B) is from 5,000:1 to 1:5,000.

3. The active compound combination may comprise, as compound (C), compounds of the following groups (1′) to (15′): (1') (1.001) cyproconazole, (1.002) difenoconazole, (1.003) epoxiconazole, (1.004) fenbuconazole, (1.005) fenhexamid, (1.006) fenpropidin, (1.007) fenpropimorph, (1.008) fenpyrazamine, (1.009) fluoxythioconazole, (1.010) fluquinconazole, (1.011) flutriafol, (1.012) hexaconazole, (1.013) imazalil, (1.014) imazalil sulfate, (1.015) ipconazole (1.016) ipfentrifluconazole, (1.017) mefentrifluconazole, (1.018) metconazole, (1.019) myclobutanil, (1.020) paclobutrazol, (1.021) penconazole, (1.022) prochloraz, (1.023) propiconazole, (1.024) prothioconazole, (1.025) pyrizoxazole, (1.026) spiroxamine, (1.027) tebuconazole, (1.028) tetraconazole, (1.029) triadimenol, (1.030) tridemoxazole (1.031) Triticonazole, (1.032) (1R,2S,5S)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.033) (1S,2R,5R)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.034) (2R)-2-(1-chlorocyclopropyl)-4-[(1R)-2,2-dichlorocyclopropyl]- 1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.035) (2R)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.036) (2R)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol, (1.037) (2S)-2-(1-chlorocyclopropyl)-4-[(1R)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.038) (2S)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, (1.039) (2S)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1 -yl)propan-2-ol, (1.040) (R)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.041) (S)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.042) [3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridin-3-yl)methanol, (1.043) 1-({(2R,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole, (1.044) 1-({(2S,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole, oxolan-2-yl}methyl)-1H-1,2,4-triazole, (1.045) 1-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl thiocyanate, (1.046) 1-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl Thiocyanate, (1.047) 1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol-5-yl thiocyanate, (1.048) 2-[(2R,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.049) 2-[(2R,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.050) 2-[(2R,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole -3-thione, (1.051) 2-[(2R,4S,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.052) 2-[(2S,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.053) 2-[(2S,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione )-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.054) 2-[(2S,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.055) 2-[(2S,4S,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H -1,2,4-triazole-3-thione, (1.056) 2-[1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.057) 2-[6-(4-bromophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol, (1.058) 2-[6-(4-chlorophenoxy)-2-(trifluoromethyl)-3-pyridyl]-1-(1,2,4-triazol-1-yl)propan-2-ol, (1.059) 2-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.060) 2-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione, (1.061) 2-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thione (1.062) 3-[2-(1-chlorocyclopropyl)-3-(3-chloro-2-fluoro-phenyl)-2-hydroxy-propyl]imidazole-4-carbonitrile, (1.063) 5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, (1.064) 5-(allylsulfanyl)-1-{ [3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole, (1.065) 5-(allylsulfanyl)-1-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole, (1.066) 5-(allylsulfanyl)-1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}- 1H-1,2,4-triazole, (1.068) N'-(2-chloro-5-methyl-4-phenoxyphenyl)-N-ethyl-N-methylimidoformamide, (1.069) N'-[2-chloro-4-(2-fluorophenoxy)-5-methylphenyl]-N-ethyl-N-methylimidoformamide, (1.070) N'-[5-bromo-6-(2,3-dihydro-1H-inden-2-yloxy)-2-methylpyridin-3-yl]-N-ethyl-N-methylimidoformamide, (1.071) N'-{4-[(4,5-dichloro-1,3-thiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylimidoformamide, (1.072) N'-{5-bromo-2-methyl-6-[(1-propoxypropan-2-yl)oxy]pyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.073) N'-{5-bromo-6-[(1R)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.074) N'-{5-bromo-6-[(1S)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.075) N'-{5-bromo-6-[(cis-4-isopropyl an inhibitor of ergosterol synthesis selected from the group consisting of N'-{5-bromo-6-[(trans-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.076)N'-{5-bromo-6-[(trans-4-isopropylcyclohexyl)oxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, (1.077)N'-{5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methylpyridin-3-yl}-N-ethyl-N-methylimidoformamide, and (1.078)N-isopropyl-N'-[5-methoxy-2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-phenylethyl)phenyl]-N-methylimidoformamide, (2') (2.001) benzovindiflupyr, (2.002) bixafen, (2.003) boscalid, (2.004) carboxin, (2.005) cyclobutrifluram, (2.006) fluveneteram, (2.007) fluindapyr, (2.008) fluopyram, (2.009) flutolanil, (2.010) fluxapyroxad, (2.011) furametpyr, (2.012) inpirfluxam, (2.013) isofetamide, (2.014) isoflucipram, (2.015) isopyrazam, ( 2.016) Penflufen, (2.017) Penthiopyrad, (2.018) Pydiflumetofen, (2.019) Pyrapropoin, (2.020) Pyraziflumide, (2.021) Sedaxane, (2.022) Thifluzamide, (2.023) 1,3-dimethyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide, (2.024) 1,3-dimethyl-N-[(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl] ]-1H-pyrazole-4-carboxamide, (2.025) 1,3-dimethyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2.026) 1-methyl-3-(trifluoromethyl)-N-[2'-(trifluoromethyl)biphenyl-2-yl]-1H-pyrazole-4-carboxamide, (2.027) 2-fluoro-6-(trifluoromethyl)-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden -4-yl)benzamide, (2.028) 3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide, (2.029) 3-(difluoromethyl)-1-methyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide, (2.030) 3-(difluoromethyl)-N-[(3R)-7-fluoro-1,1,3-trimethyl-2,3-Dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.031) 3-(difluoromethyl)-N-[(3S)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide, (2.032) 5,8-difluoro-N-[2-(2-fluoro-4-{[4-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)ethyl]quinazolin-4-amine, (2.033) N-[(1R,4S)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl an inhibitor of the respiratory chain at complex I or II selected from the group consisting of N-[(1S,4R)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.034) N-[(1S,4R)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.035) N-[1-(2,4-dichlorophenyl)-1-methoxypropan-2-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, (2.036) N-[rac-(1S,2S)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)nicotinamide, (3') (3.001) ametoctrazin, (3.002) amisulbrom, (3.003) azoxystrobin, (3.004) methoxystrobin, (3.005) cumoxystrobin, (3.006) cyazofamid, (3.007) dimoxystrobin, (3.008) enoxastrobin, (3.009) famoxadone, (3.010) fenamidone, (3.011) fenpicoxamide, (3.012) flurylpicoxamide, (3.013) flufenoxystrobin, (3.014 ) fluoxastrobin, (3.015) kresoxim-methyl, (3.016) mandestrobin, (3.017) methallylpicoxamide, (3.018) metominostrobin, (3.019) methyltetraprole, (3.020) orysastrobin, (3.021) picoxystrobin, (3.022) pyraclostrobin, (3.023) pyrametostrobin, (3.024) pyraoxystrobin, (3.025) trifloxystrobin, (3.026) (2E)-2-{2-[({[(1E )-1-(3-{[(E)-1-fluoro-2-phenylvinyl]oxy}phenyl)ethylidene]amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide, (3.027) (2E,3Z)-5-{[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.028) (2R)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide Inhibitors of the respiratory chain at complex III selected from the group consisting of: acetamide, (3.029) (2S)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide, (3.030) N-(3-ethyl-3,5,5-trimethylcyclohexyl)-3-formamido-2-hydroxybenzamide, (3.031) (2E,3Z)-5-{[1-(4-chloro-2-fluorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide, (3.032) methyl {5-[3-(2,4-dimethylphenyl)-1H-pyrazol-1-yl]-2-methylbenzyl}carbamate, (4') (4.001) carbendazim, (4.002) diethofencarb, (4.003) ethaboxam, (4.004) fluopicolide, (4.005) fluopimomide, (4.006) metrafenone, (4.007) pencycuron, (4.008) pyridaclomethyl, (4.009) pyriophenone (clazafenone), (4.010) thiabendazole, (4.011) thiophanate-methyl, (4.012) zoxamide, (4.013) 3-chloro-5-(4-chlorophenyl)-4-(2,6-difluorophenyl)-6-methyl pyridazine, (4.014) 3-chloro-5-(6-chloropyridin-3-yl)-6-methyl-4-(2,4,6-trifluorophenyl)pyridazine, (4.015) 4-(2-bromo-4-fluorophenyl)-N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.016) 4-(2-bromo-4-fluorophenyl)-N-(2-bromo-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.017) 4-(2-bromo-4-fluorophenyl)-N-(2- (4.018) 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.019) 4-(2-bromo-4-fluorophenyl)-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.020) 4-(2-bromo-4-fluorophenyl)-N-(2-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.021) 4-(2-chloro-4-fluorophenyl)-N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.022) 4-(2-chloro-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.023) 4-(2-chloro-4-fluorophenyl)-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.024) 4-(2-chloro-4-fluorophenyl)-N-(2-fluorophenyl)-1,Inhibitors of mitosis and cell division selected from the group consisting of: 3-dimethyl-1H-pyrazol-5-amine, (4.025) 4-(4-chlorophenyl)-5-(2,6-difluorophenyl)-3,6-dimethylpyridazine, (4.026) N-(2-bromo-6-fluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.027) N-(2-bromophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (4.028) N-(4-chloro-2,6-difluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine, (5') (5.001) Bordeaux mixture, (5.002) Captafol, (5.003) Captan, (5.004) Chlorothalonil, (5.005) Copper hydroxide, (5.006) Copper naphthenate, (5.007) Copper oxide, (5.008) Copper oxychloride, (5.009) Copper(II) sulfate, (5.010) Dithianon, (5.011) Dodine, (5.012) Folpet, (5.013) Mancozeb, (5.014) Maneb, (5.015) Metiram, (5.016) Methiram compounds capable of multisite action selected from the group consisting of: thiram zinc, (5.017) oxine copper, (5.018) propineb, (5.019) sulfur preparations containing sulfur and calcium polysulfide, (5.020) thiram, (5.021) zineb, (5.022) ziram, (5.023) 6-ethyl-5,7-dioxo-6,7-dihydro-5H-pyrrolo[3',4':5,6][1,4]dithiino[2,3-c][1,2]thiazole-3-carbonitrile, (6') Compounds that can induce host defense selected from the group consisting of (6.001) acibenzolar-S-methyl, (6.002) fosetyl aluminum, (6.003) fosetyl calcium, (6.004) fosetyl sodium, (6.005) isotianil, (6.006) phosphorous acid and its salts, (6.007) probenazole, (6.008) tiadinil, (7') inhibitors of amino acid and / or protein biosynthesis selected from the group consisting of (7.001) cyprodinil, (7.002) kasugamycin, (7.003) kasugamycin hydrochloride hydrate, (7.004) oxytetracycline, (7.005) pyrimethanil, (8') (8.001) the inhibitor of ATP production selected from the group consisting of silthiofam, (9') inhibitors of cell wall synthesis selected from the group consisting of (9.001) benthiavalicarb, (9.002) dimethomorph, (9.003) flumorph, (9.004) iprovalicarb, (9.005) mandipropamid, (9.006) pyrimorph, (9.007) valifenalate, (9.008) (2E)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-1-(morpholin-4-yl)prop-2-en-1-one, (9.009) (2Z)-3-(4-tert-butylphenyl)-3-(2-chloropyridin-4-yl)-1-(morpholin-4-yl)prop-2-en-1-one, (10') (10.001) Fluoxapiprolin, (10.002) Natamycin, (10.003) Oxathiapiprolin, (10.004) Propamocarb, (10.005) Propamocarb hydrochloride, (10.006) Propamocarb fosetylate, (10.007) Tolclofos-methyl, (10.008) 1-(4-{4-[(5R)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl) )-1H-pyrazol-1-yl]ethanone, (10.009) 1-(4-{4-[(5S)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone, (10.010) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2 -oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.011) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-chloro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.012) 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-(4-{5-[2-fluoro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, pyro-6-(prop-2-yn-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazol-2-yl)piperidin-1-yl]ethanone, (10.013) 2-{(5R)-3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate, (10.014) 2-{(5S)-3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate, (10.015) 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4- yl]-4,5-dihydro-1,2-oxazol-5-yl}phenyl methanesulfonate, (10.016) 3-[2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (10.017) 9-fluoro-3-[2-(1- {[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (10.018) 3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]- Inhibitors of lipid and membrane synthesis selected from the group consisting of 1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (10.019) 3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-9-fluoro-1,5-dihydro-2,4-benzodioxepin-6-yl methanesulfonate, (11') inhibitors of melanin biosynthesis selected from the group consisting of (11.001) tolprocarb, (11.002) tricyclazole, (12') inhibitors of nucleic acid synthesis selected from the group consisting of (12.001) benalaxyl, (12.002) benalaxyl-M (chiralaxyl), (12.003) metalaxyl, (12.004) metalaxyl-M (mefenoxam); (13') inhibitors of signal transduction selected from the group consisting of (13.001) fludioxonil, (13.002) iprodione, (13.003) procymidone, (13.004) proquinazide, (13.005) quinoxyfen, (13.006) vinclozolin, (14') (14.001) fluazinam, (14.002) meptyldinocap, a compound capable of acting as an uncoupler selected from the group consisting of (15') (15.001) abscisic acid, (15.002) aminopyrifen, (15.003) benthazole, (15.004) bethoxadin, (15.005) capsimycin, (15.006) carvone, (15.007) quinomethionate, (15.008) chlorinconazide, (15.009) khuraneb, (15.010) cyflufenamid, (15.011) cymoxanil, (15.012) ) cyprosulfamide, (15.013) dipimethitron, (15.014) fluthianil, (15.015) flufenoxadiazam, (15.016) flumethylsulfolim, (15.017) ipflufenoquin, (15.018) methyl isothiocyanate, (15.019) mildiomycin, (15.020) nickel dimethyldithiocarbamate, (15.021) nitroisopropyl, (1 5.022) Oxyfenthiin, (15.023) Pentachlorophenol and salts, (15.024) Picarburazox, (15.025) Quinofumelin, (15.026) D-tagatose, (15.027) Tebufloquine, (15.028) Tecloftalam, (15.029) Tolnifanide, (15.030) 2-(6-benzylpyridin-2-yl)quinazoline, (15.031) 2-[6-(3- fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline, (15.032) 2-phenylphenol and salts, (15.033) 4-amino-5-fluoropyrimidin-2-ol (tautomer from 4-amino-5-fluoropyrimidin-2(1H)-one), (15.034) 4-oxo-4-[(2-phenylethyl)amino]butanoic acid, (15.035) 5-amino-1,3,4-Thiadiazole-2-thiol, (15.036) 5-chloro-N'-phenyl-N'-(prop-2-yn-1-yl)thiophene-2-sulfonohydrazide, (15.037) 5-fluoro-2-[(4-fluorobenzyl)oxy]pyrimidin-4-amine, (15.038) 5-fluoro-2-[(4-methylbenzyl)oxy]pyrimidin-4-amine, (15.039) but-3-yn-1-yl {6-[({[(Z)-(1-methyl-1H-tetrazol-5-yl)(phenyl)methylene]amino}oxy)methyl]pyridin-2-yl}carbamate, (15.040) ethyl (2Z)-3-amino-2-cyano-3-phenylacrylate, (15.041) phenazine-1-carboxylic acid, (15.042) propyl 3,4,5-trihydroxybenzoate, (15.043) quinolin-8-ol, (15.044) quinolin-8-ol sulfuric acid (2:1), (15.045) 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.046) 1-(5-(fluoromethyl)-6-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.047) 1-(5,6-dimethylpyridin-3-yl)-4,4-difluoro-3 ,3-dimethyl-3,4-dihydroisoquinoline, (15.048) 1-(6-(difluoromethyl)-5-methoxy-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.049) 1-(6-(difluoromethyl)-5-methyl-pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.050) 1-(6,7-dimethylpyrazolo[1,5 -a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline, (15.051) 2-{2-fluoro-6-[(8-fluoro-2-methylquinolin-3-yl)oxy]phenyl}propan-2-ol, (15.052) 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.053) 3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-8-fluoroquinoline, (15.054) 3-(4,4-difluoro-5,5-dimethyl-4,5-dihydrothieno[2,3-c]pyridin-7-yl)quinoline, (15.055) 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinolin-1-yl)quinoline, (15.056) 5-bromo-1-(5,6-dimethylpyridin-3-yl)-3,3-dimethyl-3,4-dihydroisoquinoline, (15.057) 8-fluoro-3-(5-fluoro-3,3,4,4-tetramethyl- (15.058) 8-fluoro-3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-quinoline, (15.059) 8-fluoro-N-(4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl)quinoline-3-carboxamide, (15.060) 8-fluoro-N-[(2S)-4,4,4-trifluoro-2-methyl-1-phenylbutan-2-yl]quinoline-3-carboxamide, (15.061) 9-fluoro-2 , 2-dimethyl-5-(quinolin-3-yl)-2,3-dihydro-1,4-benzoxazepine, (15.062) N-(2,4-dimethyl-1-phenylpentan-2-yl)-8-fluoroquinoline-3-carboxamide, (15.063) N-[(2S)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063A) N-[(2R)-2,4-dimethyl-1-phenylpentan-2-yl]-8-fluoroquinoline-3-carboxamide, (15.063B) 2-benzyl- N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.063C) (2S)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.063D) (2R)-2-benzyl-N-(8-fluoro-2-methyl-3-quinolyl)-2,4-dimethyl-pentanamide, (15.064) 1,1-diethyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.065) 1,3-Dimethoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.066) 1-[[3-fluoro-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl]methyl]azepan-2-one, (15.067) 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.068) 1-methyl- 1-methoxy-1-methyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.069) 1-methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15.070) 1-methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]urea, (15 . 071) 2,2-difluoro-N-methyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide, (15.072) 3,3-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]piperidin-2-one, (15.073) 3-ethyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl ]methyl]urea, (15.074) 4,4-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.075) 4,4-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, (15.076) 4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl dimethylcarbamate, (15.077) 5,5-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]isoxazolidin-3-one, (15.078) 5-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-Oxadiazol-3-yl]phenyl]methyl]pyrrolidin-2-one, (15.079) 1-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}-1H-pyrazole-4-carboxylate, (15.080) methyl {4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}carbamate, (15.081) N-(1-methylcyclopropyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.082) N-(2,4-difluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.083) N,2-dimethoxy-N-[[ 4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.084) N,N-dimethyl-1-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}-1H-1,2,4-triazol-3-amine, (15.085) N-[(E)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (1 5.086) N-[(E)-N-methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.087) N-[(Z)-methoxyiminomethyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.088) N-[(Z)-N-methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2 ,4-oxadiazol-3-yl]benzamide, (15.089) N-[[2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]-3,3,3-trifluoro-propanamide, (15.090) N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.091) N-[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]cyclopropanecarboxamide, (15.092) N-{2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}butanamide, (15.093) N-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzyl}cyclopropanecarboxamide, (15.094) N-{4-[5-(trifluoromethyl)-1,2,4-oxadiazole- 3-yl]phenyl}propanamide, (15.095) N-allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]acetamide, (15.096) N-allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.097) N-ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-, other antifungal agents selected from the group consisting of: N-methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]propanamide, (15.098) N-methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]cyclopropanecarboxamide, (15.099) N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, (15.100) N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzenecarbothioamide, (15.101) N-methyl-N-phenyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide; and at least one further antifungally active compound selected from the at least one further active compound (C) is different from the compound (A) and the compound (B), 2. The active compound combination according to claim 1.

4. The compound (C) is (1.002) difenoconazole, (1.009) fluoxythioconazole, (1.015) ipconazole, (1.017) mefentrifluconazole, (1.024) prothioconazole, (1.026) spiroxamine, (1.027) tebuconazole, (2.001) benzovindiflupyr, (2.002) bixafen, (2.007) fluindapyr, (2.008) benzovindiflupyr, (2.009) benzovindiflupyr, (2.009) benzovindiflupyr, (2.010) benzovindiflupyr, (2.011) benzovindiflupyr, (2.012) benzovindiflupyr, (2.013) benzovindiflupyr, (2.014) benzovindiflupyr, (2.015) ipconazole, (1.017) mefentrifluconazole, (1.024) prothioconazole, (1.026) spiroxamine, (1.027) tebuconazole, (2.001) benzovindiflupyr, (2.002) bixafen, (2.007) fluindapyr, (2.016) benzovindiflupyr, (2.017) benzovindiflupyr, (2.018) benzovindiflupyr, (2.019 ... .008) fluopyram, (2.010) fluxapyroxad, (2.012) inpirfluxam, (2.014) isoflucipram, (2.016) penflufen, (2.017) penthiopyrad, (2.018) pydiflumetofen, (2.021) sedaxane, (3.003) azoxystrobin, (3.011) fenpicoxamid, (3.014) fluoxastrobin, (3.016 ) Mandestrobin, (3.021) Picoxystrobin, (3.022) Pyraclostrobin, (3.025) Trifloxystrobin, (4.007) Pencycuron, (4.009) Pyriophenone (Clazafenone), (4.011) Thiophanate-methyl, (5.004) Chlorothalonil, (5.011) Dodine, (5.012) Folpet, (5.013) Mancozeb, (5.018) Pro selected from ropineb, (6.005) isotianil, (7.005) pyrimethanil, (12.003) metalaxyl, (12.004) metalaxyl-M (mefenoxam), (13.001) fludioxonil, (13.004) proquinazid, (14.001) fluazinam, (14.002) meptyldinocap, (15.010) cyflufenamid and (15.025) quinofumelin; 4. An active compound combination according to claim 3.

5. 4. The active compound combination according to claim 3, wherein the weight ratio of compound (A) to compound (C) is from 5,000:1 to 1:5,000.

6. 10. A composition for controlling harmful microorganisms in crop protection and the protection of industrial materials, characterized in that, in addition to at least one carrier and / or surfactant, it contains the active compound combination according to claim 1.

7. 10. A method for controlling harmful microorganisms in crop protection and the protection of industrial materials, characterized in that the method comprises applying an active compound combination according to at least one of claims 1 to 5 or a composition according to claim 6 to the harmful microorganisms and / or their habitat.

8. Use of an active compound combination according to at least one of claims 1 to 5 or a composition according to claim 6 for the treatment of transgenic plants.

9. Use of an active compound combination according to at least one of claims 1 to 5 or a composition according to claim 6 for the treatment of seeds.

10. Seeds coated with an active compound combination according to at least one of claims 1 to 5 or with a composition according to claim 6.