Method for inhibiting 2,6-dimethylpyridine odor
A composition of specific components is used to mask 2,6-dimethylpyridine odor in foods and environments by applying it to the object, effectively reducing the odor's perception and intensity.
Patent Information
- Application Number
- JP2023113267
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2023-07-10
- Publication Date
- 2025-01-23
AI Technical Summary
There is a need to suppress the unpleasant odor of 2,6-dimethylpyridine in various objects, including foods and spaces, as existing methods are inadequate in effectively masking or eliminating this odor.
A composition comprising specific components such as sclareol, (3R/3S)-3-sulfanylpentan-2-one, 2-methyl-3-furanthiol, and others, is used to mask or reduce the 2,6-dimethylpyridine odor by applying them to the object or space, either as an additive or in a formulation.
The composition effectively suppresses or masks the 2,6-dimethylpyridine odor, reducing its intensity and perception, whether it is present initially or develops over time, in foods, waste, or other environments.
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Abstract
Description
[Technical field]
[0001] The present invention relates to a technique for suppressing 2,6-dimethylpyridine odor. Specifically, the present invention relates to a method for suppressing 2,6-dimethylpyridine odor. [Background technology]
[0002] There is a demand for the development of a technique for suppressing specific odors, such as unpleasant odors, in foods and other objects. For example, methods for suppressing specific odors by blending various ingredients have been reported. Summary of the Invention [Problem to be solved by the invention]
[0003] An object of the present invention is to provide a technique for suppressing the odor of 2,6-dimethylpyridine. Specifically, an object of the present invention is to provide a method for suppressing the odor of 2,6-dimethylpyridine. [Means for solving the problem]
[0004] Means of the Invention The present inventors have conducted extensive research to solve the above problems, and as a result have found various components that suppress the 2,6-dimethylpyridine odor, thereby completing the present invention.
[0005] That is, the present invention can be exemplified as follows. [1] A composition for suppressing the odor of 2,6-dimethylpyridine in a subject, comprising: A composition comprising the following component (A): (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde. [2] The composition (specifically, the composition described in [1]) wherein the target is an object or a space. [3] The composition (specifically, the composition described in [2]) wherein the item is food or waste. [4] A composition for the manufacture of an article, comprising: A composition comprising the following component (A): (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil (PEPPER OIL BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde. [5] The composition (specifically, the composition described in [4]) wherein the article is a food product. [6] The composition (specifically, the composition described in [4] or [5]) above, wherein the article is an article in which the odor of 2,6-dimethylpyridine is suppressed. [7] The composition (specifically, the composition according to any one of [2] to [6]) wherein the article contains 2,6-dimethylpyridine and / or a component capable of producing 2,6-dimethylpyridine. [8] 1. A method for inhibiting 2,6-dimethylpyridine odor in a subject, comprising: The method comprises the step of applying component (A) to the subject: (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde. [9] The method (specifically, the method described in [8]) above, wherein the object is an object or a space.
[10] The method (specifically, the method described in [9]) above, wherein the item is food or waste.
[11] The object is an article, The article is a food product, The method (specifically, the method described in [8]) wherein the step is a step of adding the component (A) to a raw material of the article.
[12] 1. A method of manufacturing an article, comprising the steps of: The method includes the step of adding component (A) to a raw material of the article: (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde.
[13] The method (specifically, the method described in
[12] ) above, wherein the item is a food product.
[14] The method (specifically, the method described in
[12] or
[13] ) above, wherein the article is an article in which the 2,6-dimethylpyridine odor is suppressed.
[15] The method (specifically, the method described in any one of [9] to
[14] ) wherein the article or the raw material contains 2,6-dimethylpyridine and / or a component capable of producing 2,6-dimethylpyridine.
[16] The content of the component (A) in the article is 0.001 ppt (w / w) to 1000 ppm (w / w). The method (specifically, the method described in any one of [9] to
[15] ) above, in which the compound is added as follows.
[17] The article is a food product, The method (specifically, the method described in
[16] ) above, wherein the content is an intake concentration. Effect of the Invention
[0006] According to the present invention, the odor of 2,6-dimethylpyridine can be suppressed. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0007] The present invention will be described in detail below.
[0008] <1> Active ingredients In order to suppress the odor of 2,6-dimethylpyridine, the following component (A) is used as an active ingredient: (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde.
[0009] As component (A), one kind of component may be used, or two or more kinds of components may be used in combination. The combination of components selected as component (A) is not particularly limited.
[0010] Ingredient (A) is also referred to as the "active ingredient."
[0011] By utilizing the active ingredient, the 2,6-dimethylpyridine odor can be suppressed, that is, the effect of suppressing the 2,6-dimethylpyridine odor can be obtained. This effect is also called the "masking effect." "Suppression of 2,6-dimethylpyridine odor" is also called "reduction of 2,6-dimethylpyridine odor" or "masking of 2,6-dimethylpyridine odor." Note that "suppression of 2,6-dimethylpyridine odor" includes both the suppression of 2,6-dimethylpyridine odor that may occur in the future and the suppression of 2,6-dimethylpyridine odor that has already occurred. Also, "suppression of 2,6-dimethylpyridine odor" includes the suppression of 2,6-dimethylpyridine odor that may occur in the future and the suppression of 2,6-dimethylpyridine odor that has already occurred. This also includes the case where the odor is completely eliminated. "2,6-dimethylpyridine odor" refers to the odor exhibited by 2,6-dimethylpyridine. "Odor" may refer to retronasal aroma (i.e., the odor felt from the throat to the nasal cavity when eating the product) and / or orthonasal aroma (i.e., the odor smelled directly from the nose). Specifically, by using an active ingredient, the 2,6-dimethylpyridine odor can be suppressed compared to when the active ingredient is not used. Thus, the masking effect can be determined by measuring and comparing the 2,6-dimethylpyridine odor when the active ingredient is not used and when the active ingredient is used. That is, it can be determined that the masking effect has been obtained when the intensity of the 2,6-dimethylpyridine odor is smaller when the active ingredient is used compared to when the active ingredient is not used. The measurement and comparison of the 2,6-dimethylpyridine odor can be performed, for example, by sensory evaluation by a specialist panel.
[0012] Specifically, the use of the active ingredient can suppress the 2,6-dimethylpyridine odor in a subject. The subject is not particularly limited as long as it is desired to suppress the 2,6-dimethylpyridine odor.
[0013] The target may be an article. The article may already have a 2,6-dimethylpyridine odor, or may be capable of having a 2,6-dimethylpyridine odor in the future. An example of an article that already has a 2,6-dimethylpyridine odor is an article that contains 2,6-dimethylpyridine. An example of an article that may have a 2,6-dimethylpyridine odor in the future is an article that contains a component that can produce 2,6-dimethylpyridine. That is, the article may contain 2,6-dimethylpyridine and / or a component that can produce 2,6-dimethylpyridine. The article may contain a component that can produce 2,6-dimethylpyridine and / or 2,6-dimethylpyridine, for example, by containing a material that contains 2,6-dimethylpyridine and / or a component that can produce 2,6-dimethylpyridine.
[0014] Examples of the article include food. Food also includes beverages. Food also includes seasonings. Food may be, for example, liquid or solid. Food containing 2,6-dimethylpyridine and / or components capable of producing 2,6-dimethylpyridine includes black tea, whiskey, coffee, beer, soy sauce, meat, and foods containing them. Food is not limited to general foods, but also includes so-called health foods or medical foods such as nutritional supplements, nutritional functional foods, and foods for specified health uses. That is, for example, the foods exemplified above may be provided as general foods, or as health foods or medical foods.
[0015] The article also includes waste. The waste may be, for example, a solid or a liquid (i.e., waste liquid). The waste includes waste discharged from a facility where 2,6-dimethylpyridine may be generated. Such facilities include facilities that handle articles containing 2,6-dimethylpyridine and / or components that may generate 2,6-dimethylpyridine, and facilities that perform operations that generate 2,6-dimethylpyridine and / or components that may generate 2,6-dimethylpyridine. The waste also includes discarded food. The food is as described above.
[0016] The target space also includes the space of a facility where 2,6-dimethylpyridine may be generated (specifically, the space inside and around such a facility). The facilities where 2,6-dimethylpyridine may be generated are as described above.
[0017] When an active ingredient can form a salt, the active ingredient may be used in its free form, in its salt form, or in its combination. That is, the term "active ingredient" refers to the active ingredient in its free form, or a salt thereof, or a combination thereof, unless otherwise specified. For example, the term "tridecylic acid" may mean free tridecylic acid, a salt thereof, or a combination thereof, unless otherwise specified. For salts of active ingredients, the description of salts of ingredients capable of producing 2,6-dimethylpyridine described below can be applied mutatis mutandis.
[0018] As the active ingredient, a commercially available product may be used, or one obtained by appropriate production may be used. The method for producing the active ingredient is not particularly limited. The active ingredient can be produced, for example, by chemical synthesis, enzyme reaction, fermentation, extraction, or a combination thereof. The active ingredient may be purified to a desired degree or may not be purified. That is, as the active ingredient, a purified product may be used, or a material containing the active ingredient may be used. As the active ingredient, for example, a material having an active ingredient content of 1% (w / w) or more, 5% (w / w) or more, 10% (w / w) or more, 30% (w / w) or more, 50% (w / w) or more, 70% (w / w) or more, 90% (w / w) or more, or 95% (w / w) or more may be used.
[0019] In addition, when a material containing an active ingredient is used, the amount of the active ingredient (e.g., the content (concentration) or amount used) is to be calculated based on the amount of the active ingredient itself in the material.
[0020] <2> Compositions of the Invention The composition of the present invention is a composition that contains an active ingredient.
[0021] That is, the composition of the present invention is a composition containing the following component (A): (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde.
[0022] By utilizing the composition of the present invention, the 2,6-dimethylpyridine odor can be suppressed, that is, a masking effect can be obtained. Thus, the composition of the present invention may be used to suppress the 2,6-dimethylpyridine odor. That is, the composition of the present invention may be, for example, a composition for suppressing the 2,6-dimethylpyridine odor. Specifically, the composition of the present invention may be, for example, a composition for suppressing the 2,6-dimethylpyridine odor in a target. Specifically, the composition of the present invention may be, for example, a composition for suppressing the 2,6-dimethylpyridine odor in an item such as food or waste. Specifically, the composition of the present invention may be, for example, a composition for suppressing the 2,6-dimethylpyridine odor in a space.
[0023] Furthermore, by utilizing the composition of the present invention, it is possible to manufacture articles such as food products in which the 2,6-dimethylpyridine odor is suppressed. Thus, the composition of the present invention may be utilized in the manufacture of articles such as food products (specifically, the manufacture of articles such as food products in which the 2,6-dimethylpyridine odor is suppressed). That is, the composition of the present invention may be, for example, a composition for the manufacture of articles such as food products (specifically, the manufacture of articles such as food products in which the 2,6-dimethylpyridine odor is suppressed).
[0024] The composition of the present invention may be, for example, a seasoning. Specifically, the composition of the present invention may be, for example, a seasoning for suppressing 2,6-dimethylpyridine odor in food, or a seasoning for food production (specifically, production of food with suppressed 2,6-dimethylpyridine odor).
[0025] The composition of the present invention may be, for example, a deodorant. The composition of the present invention may be, specifically, for example, a deodorant for suppressing 2,6-dimethylpyridine odor in an object. The composition of the present invention may be, more specifically, for example, a deodorant for suppressing 2,6-dimethylpyridine odor in an item such as waste. The composition of the present invention may be, more specifically, for example, a deodorant for suppressing 2,6-dimethylpyridine odor in a space. "A deodorant for suppressing 2,6-dimethylpyridine odor in an object (e.g., an item or space)" may mean a deodorant for suppressing 2,6-dimethylpyridine odor used for an object (e.g., an item or space).
[0026] The composition of the present invention may be used to suppress the odor of 2,6-dimethylpyridine or to produce articles such as food in the manner described in the method of the present invention below.
[0027] The composition of the present invention may be composed of an active ingredient, or may contain ingredients other than the active ingredient. The composition of the present invention may exclude a composition composed of an active ingredient. As the ingredient other than the active ingredient, one kind of ingredient may be used, or two or more kinds of ingredients may be used in combination.
[0028] Ingredients other than the active ingredient are not particularly limited as long as they do not impair the masking effect. Ingredients other than the active ingredient can be appropriately selected according to various conditions such as the usage mode of the active ingredient. Ingredients other than the active ingredient include ingredients that are mixed into food or medicine. Specific examples of ingredients other than the active ingredient include the food ingredients described below.
[0029] The composition of the present invention can be produced, for example, by appropriately mixing the active ingredient and, optionally, other ingredients.
[0030] The composition of the present invention may be, for example, appropriately formulated. In the formulation, additives may be appropriately used. Examples of additives include excipients, binders, disintegrants, lubricants, stabilizers, flavorings, diluents, surfactants, and solvents. Additives can be appropriately selected according to various conditions such as the shape of the composition of the present invention.
[0031] The shape of the composition of the present invention is not particularly limited. The composition of the present invention may be in any shape, such as a powder, a flake, a tablet, a paste, or a liquid.
[0032] The content and content ratio of each component (i.e., active ingredient and optional other components) in the composition of the present invention are not particularly limited as long as the masking effect can be obtained.The content and content ratio of each component in the composition of the present invention can be appropriately set according to various conditions such as the use mode of the composition of the present invention.
[0033] The content of the active ingredient in the composition of the present invention is more than 0% (w / w) and less than 100% (w / w). The content of the active ingredient in the composition of the present invention may be, for example, 1 ppt (w / w) or more, 10 ppt (w / w) or more, 100 ppt (w / w) or more, 1 ppb (w / w) or more, 10 ppb (w / w) or more, 100 ppb (w / w) or more, 1 ppm (w / w) or more, 10 ppm (w / w) or more, 100 ppm (w / w) or more, 1000 ppm (w / w) or more, 1% (w / w) or more, 2% (w / w) or more, 5% (w / w) or more, or 10% (w / w) or more, and may be 100% (w / w) or less, 100% (w / w) or less. ), 99.9% (w / w) or less, 90% (w / w) or less, 50% (w / w) or less, 20% (w / w) or less, 10% (w / w) or less, 5% (w / w) or less, 2% (w / w) or less, 1% (w / w) or less, 1000 ppm (w / w) or less, 100 ppm (w / w) or less, 10 ppm (w / w) or less, or 1 ppm (w / w) or less, or any non-consistent combination thereof. The content of the active ingredient in the composition of the present invention may be, for example, 1 ppt (w / w) to 1 ppm (w / w), 1 ppm (w / w) to 10 ppm (w / w), 10 ppm (w / w) to 100 ppm (w / w), 100 ppm (w / w) to 1000 ppm (w / w), 1000 ppm (w / w) to 1% (w / w), 1% (w / w) to 10% (w / w), or 10% (w / w) to 20% (w / w). The content of the active ingredient in the composition of the present invention may be, for example, 1 ppt (w / w) to 10% (w / w), 1 ppt (w / w) to 1% (w / w), or 1 ppt (w / w) to 1000 ppm (w / w). When the composition of the present invention contains two or more active ingredients, the contents of those two or more active ingredients in the composition of the present invention may be set independently or in total within the range of the contents of the active ingredients in the composition of the present invention exemplified above (however, the total content of those two or more active ingredients in the composition of the present invention is 100% (w / w) or less). When the composition of the present invention contains two or more active ingredients, the "content of the active ingredients in the composition of the present invention" means the total content of those two or more active ingredients in the composition of the present invention, unless otherwise specified.
[0034] The content of each component (i.e., the active ingredient and optionally other ingredients) in the composition of the present invention can be set, for example, so as to obtain the amount of each component added in the method of the present invention described below.
[0035] The content of each component (i.e., active ingredient and optionally other components) in the composition of the present invention can be set so as to obtain the use concentration of each component in the method of the present invention described below. The use concentration of each component may be the concentration when the composition of the present invention is used in the form of a liquid. The use concentration of the active ingredient in the method of the present invention includes the concentration of the active ingredient in the solution containing the active ingredient used in the method of the present invention.
[0036] Each component (i.e., active ingredient and optional other components) contained in the composition of the present invention may be mixed together and contained in the composition of the present invention, or may be contained separately or in any combination in the composition of the present invention.For example, the composition of the present invention may be provided as a set of each component packaged separately.In such a case, the components contained in the set can be used together as appropriate when used.
[0037] <3> Methods of the Invention The method of the present invention is a method which comprises the step of utilizing an active ingredient.
[0038] That is, the method of the present invention is a method comprising the step of utilizing the following component (A): (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and 2,6-dichlorobenzaldehyde. At least one component selected from the group:
[0039] According to the method of the present invention, specifically by utilizing the active ingredient, the 2,6-dimethylpyridine odor can be suppressed, that is, a masking effect is obtained. Thus, the method of the present invention may be carried out for suppressing the 2,6-dimethylpyridine odor. That is, the method of the present invention may be, for example, a method for suppressing the 2,6-dimethylpyridine odor. The method is also referred to as the "masking method of the present invention". Specifically, the method of the present invention may be, for example, a method for suppressing the 2,6-dimethylpyridine odor in a subject. More specifically, the method of the present invention may be, for example, a method for suppressing the 2,6-dimethylpyridine odor in an item such as food or waste. More specifically, the method of the present invention may be, for example, a method for suppressing the 2,6-dimethylpyridine odor in a space.
[0040] Furthermore, the method of the present invention, specifically by utilizing the active ingredient, can produce an article such as food in which the 2,6-dimethylpyridine odor is suppressed. Thus, the method of the present invention may be carried out for producing an article such as food (specifically, producing an article such as food in which the 2,6-dimethylpyridine odor is suppressed). That is, the method of the present invention may be, for example, a method for producing an article such as food (specifically, producing an article such as food in which the 2,6-dimethylpyridine odor is suppressed). This method is also referred to as the "production method of the present invention."
[0041] The active ingredient can be used to suppress the 2,6-dimethylpyridine odor in a target by applying it to the target. That is, the use of the active ingredient includes applying the active ingredient to a target.
[0042] For example, the active ingredient can be used to suppress the 2,6-dimethylpyridine odor or to manufacture an article such as food by adding it to the raw materials of the article such as food during the manufacture of the article such as food. That is, the use of the active ingredient (specifically, the application of the active ingredient to a target) can include adding the active ingredient to the raw materials of the article such as food. That is, the method of the present invention can be specifically, for example, a method for suppressing the 2,6-dimethylpyridine odor in an article such as food, which includes adding the active ingredient to the raw materials of the article such as food. In addition, the method of the present invention can be specifically, for example, a method for manufacturing an article such as food (specifically, a method for manufacturing an article such as food in which the 2,6-dimethylpyridine odor is suppressed), which includes adding the active ingredient to the raw materials of the article such as food. "Addition" is also called "blending".
[0043] The active ingredient may be utilized in the method of the present invention, for example, in the form of a composition of the present invention. That is, "utilization of an active ingredient" also includes utilization of a composition of the present invention. For example, "addition of an active ingredient" also includes addition of a composition of the present invention.
[0044] An article obtained by the method of the present invention is also called "the article of the present invention". For example, a food product obtained by the method of the present invention is also called "the food product of the present invention". Specifically, the article of the present invention is an article in which the 2,6-dimethylpyridine odor is suppressed. In other words, the article of the present invention is an article to which an active ingredient is added.
[0045] The suppression of 2,6-dimethylpyridine odor or the manufacture of an article may be carried out in the same manner as the manufacture of a normal article, except for the use of an active ingredient. That is, the suppression of 2,6-dimethylpyridine odor or the manufacture of an article may be carried out using the same raw materials as normal articles under the same manufacturing conditions, except for the use of an active ingredient. In addition, the raw materials and manufacturing conditions of the article may be appropriately modified and used for the suppression of 2,6-dimethylpyridine odor or the manufacture of an article.
[0046] The manner in which the article is provided is not particularly limited. For example, the article may be provided in a form that can be used as is. The food may be provided in a form that can be eaten as is, or in a form that requires preparation before or at the time of consumption, such as a concentrated product or a dried product. The product may be provided in any container, such as a retort pouch, a paper pack, a plastic bottle such as a PET bottle, a metal can such as a steel can or an aluminum can, or a glass bottle.
[0047] "Raw material for an article" means a material for manufacturing an article. For example, "raw material for a food" means a food material for manufacturing a food. The raw material for an article is not particularly limited as long as the article can be manufactured. The raw material for an article can be appropriately selected according to various conditions such as the type of the article. As an example, the raw material for a food can be a raw material that can be normally used in manufacturing a food. Specific examples of the raw material for a food include grains such as wheat flour; seasoning ingredients such as sugar, inorganic salts, organic acids, nucleic acids, amino acids, and protein hydrolysates; dairy products such as milk, cheese, and butter; fruits; vegetables; eggs; spices; flavorings; fats and oils; alcohol; dietary fiber; and pH buffers.
[0048] The active ingredient may be added to the raw material of the article at any stage of the manufacturing process of the article, as long as the masking effect is obtained. In other words, the "raw material of the article" to which the active ingredient is added may be at any stage of the manufacturing process of the article. For example, the "raw material of the article" to which the active ingredient is added may include a finished article before the active ingredient is added. The active ingredient may be added to the raw material of the article as it is, or after being appropriately prepared into a desired form such as a solution. For example, the active ingredient in any form such as a solution may be mixed with the raw material of the article, a solution containing the active ingredient may be sprayed onto the raw material of the article, or the raw material of the article may be immersed in a solution containing the active ingredient. The "addition of the active ingredient" may collectively refer to an operation in which the active ingredient coexists with the raw material of the article. Ingredients other than the active ingredient (for example, 2,6-dimethylpyridine or ingredients that can produce 2,6-dimethylpyridine) may also be added to the raw material of the article as appropriate. The description of the addition of the active ingredient may also be applied mutatis mutandis to the addition of ingredients other than the active ingredient. The components (i.e., the active ingredient and optionally other ingredients) may be added to the product ingredients all at the same time, each separately, or in any combination, and the order in which the components are added to the product ingredients is not particularly limited.
[0049] The amount and ratio of each component (i.e., active ingredient and optional other components) added in the method of the present invention are not particularly limited as long as the masking effect can be obtained. The amount and ratio of each component added in the method of the present invention can be appropriately set according to various conditions such as the type of raw material of the product and the type of the product.
[0050] The active ingredient may be added to the raw material of the product, for example, so that the content of the active ingredient in the product is within a desired range. As an example, the active ingredient may be added to the raw material of a food product, for example, so that the ingestible concentration of the active ingredient is within a desired range (for example, the ingestible concentration range of the active ingredient described below).
[0051] The content of the active ingredient in the article (e.g., ingestible concentration) is, for example, 0.001 ppt(w / w) or more, 0.002 ppt(w / w) or more, 0.005 ppt(w / w) or more, 0.01 ppt(w / w) or more, 0.02 ppt(w / w) or more, 0.05 ppt(w / w) or more, 0.1 ppt(w / w) or more, 0.2 ppt(w / w) or more, 0.5 ppt(w / w) or more, 1 ppt(w / w) or more, 2 ppt(w / w) or more, 5 ppt(w / w) or more, 10 ppt(w / w) or more, 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, 50 ppm(w / w) or more, 100 ppm(w / w) or more, 200 ppm(w / w) or more, or 500 ppm(w / w) or more; and may be 1000 ppm(w / w) or less, 500 ppm(w / w) or less, 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less Lower, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) Below, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, 2 ppt(w / w) or less, 1 ppt(w / w) or less, 0.5 ppt(w / w) or less, 0.2 ppt(w / w) or less, 0.1 ppt(w / w) or less, 0.05 ppt(w / w) or less, 0.02 ppt(w / w) or less, 0.01 ppt(w / w) or less, 0.005 ppt(w / w) or less, or 0.002 ppt(w / w) or less or any compatible combination thereof. The content of the active ingredient in the article (e.g., ingestible concentration) is specifically, for example, 0.001 ppt(w / w) to 0.002 ppt(w / w), 0.002 ppt(w / w) to 0.005 ppt(w / w), 0.005 ppt(w / w) to 0.01 ppt(w / w), 0.01 ppt(w / w) to 0.02 ppt(w / w), 0.02 ppt(w / w) to 0.05 ppt(w / w), 0.05 ppt(w / w) to 0.1 ppt(w / w), 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w)~5 ppt(w / w), 5 ppt(w / w)~10 ppt(w / w), 10 ppt(w / w)~20 ppt(w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), 50 ppm(w / w)~100 ppm(w / w), 100 ppm(w / w)~200 ppm (w / w), 200 ppm (w / w) to 500 ppm (w / w), or 500 ppm (w / w) to 1000 ppm (w / w). The content of the active ingredient in the above-exemplified products (for example, the concentration when consumed) may be, specifically, for example, 0.001 ppt (w / w) to 1000 ppm (w / w). The "ingestion concentration" can be applied to any active ingredient. When an article contains two or more active ingredients, the contents (e.g., ingestion concentration) of the two or more active ingredients in the article may be set independently or in total within the range of the contents (e.g., ingestion concentration) of the active ingredients in the article exemplified above. When an article contains two or more active ingredients, "the content of the active ingredients in the article" means the total content of the two or more active ingredients in the article, unless otherwise specified. When a food contains two or more active ingredients, "the ingestion concentration of the active ingredients" means the total ingestion concentration of the two or more active ingredients in the food, unless otherwise specified.
[0052] The content (e.g., ingestible concentration) of (3R / 3S)-3-sulfanylpentan-2-one or 6-acetyl-1,1,2,4,4,7-hexamethyltetralin in the article may be, for example, in the range of the content (e.g., ingestible concentration) of the active ingredient in the article exemplified above. In addition, the content (e.g., ingestion concentration) of (3R / 3S)-3-sulfanylpentan-2-one or 6-acetyl-1,1,2,4,4,7-hexamethyltetralin in the article is, for example, 0.001 ppt (w / w) or more, 0.002 ppt (w / w) or more, 0.005 ppt (w / w) or more, 0.01 ppt (w / w) or more, 0.02 ppt (w / w) or more, 0.05 ppt (w / w) or more, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, 0.5 ppt (w / w) or more, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more or more, 10 ppt(w / w) or more, 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, or 50 ppb(w / w) or more, and may be 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, 2 ppt(w / w) or less, 1 ppt(w / w) or less, 0.5 ppt(w / w) or less, 0.2 ppt(w / w) or less, 0.1 ppt(w / w) or less, 0.05 ppt(w / w) or less, 0.02 ppt(w / w) or less, 0.01 ppt(w / w) or less, 0.005 ppt(w / w) or less, or 0.002 ppt(w / w) or less, or any compatible combination thereof. (3R / 3S)-3-sulfanylpentan-2-one or 6-acetyl-1, The content of 1,2,4,4,7-hexamethyltetralin (e.g., ingestible concentration) is specifically, for example, 0.001 ppt(w / w) to 0.002 ppt(w / w), 0.002 ppt(w / w) to 0.005 ppt(w / w), 0.005 ppt(w / w) to 0.01 ppt(w / w), 0.01 ppt(w / w) to 0.02 ppt(w / w), 0.02 ppt(w / w) to 0.05 ppt(w / w), 0.05 ppt(w / w) to 0.1 ppt(w / w), 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w)~2 ppt(w / w), 2 ppt(w / w)~5 ppt(w / w), 5 ppt(w / w)~10 ppt(w / w), 10 ppt(w / w)~20 ppt(w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), Or it may be 50 ppb (w / w) to 100 ppb (w / w). The content (e.g., ingestible concentration) of sulfanylpentan-2-one or 6-acetyl-1,1,2,4,4,7-hexamethyltetralin may be specifically, for example, 0.001 ppt (w / w) to 100 ppb (w / w), 0.01 ppt (w / w) to 10 ppb (w / w), or 0.1 ppt (w / w) to 1 ppb (w / w).
[0053] The content of ethyl mercaptoacetate in the article (e.g., ingested concentration) may be, for example, in the range of the content of the active ingredient in the above-exemplified article (e.g., ingested concentration). The content of ethyl mercaptoacetate in the article (e.g., ingested concentration) may be, for example, 0.01 ppt (w / w) or more, 0.02 ppt (w / w) or more, 0.05 ppt (w / w) or more, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, or more, 0.5 ppt(w / w) or more, 1 ppt(w / w) or more, 2 ppt(w / w) or more, 5 ppt(w / w) or more, 10 ppt(w / w) or more, 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, or 5 ppb(w / w) or more and may be 10 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w) or less, 200 ppt (w / w) or less, 100 ppt (w / w) or less, 50 ppt (w / w) or less, 20 ppt (w / w) or less, 10 ppt (w / w) or less, 5 ppt (w / w) or less, 2 ppt (w / w) or less, 1 ppt (w / w) or less, 0.5 ppt (w / w) or less, 0.2 ppt (w / w) or less, 0.1 ppt (w / w) or less, 0.05 ppt (w / w) or less, or 0.02 ppt (w / w) or less, or any non-consistent combination thereof. The content of ethyl mercaptoacetate in the article (e.g., ingestion concentration) is specifically, for example, 0.01 ppt(w / w) to 0.02 ppt(w / w), 0.02 ppt(w / w) to 0.05 ppt(w / w), 0.05 ppt(w / w) to 0.1 ppt(w / w), 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) It may be up to 20 ppt(w / w), 20 ppt(w / w)-50 ppt(w / w), 50 ppt(w / w)-100 ppt(w / w), 100 ppt(w / w)-200 ppt(w / w), 200 ppt(w / w)-500 ppt(w / w), 500 ppt(w / w)-1 ppb(w / w), 1 ppb(w / w)-2 ppb(w / w), 2 ppb(w / w)-5 ppb(w / w), or 5 ppb(w / w)-10 ppb(w / w). The content of ethyl mercaptoacetate in the article (e.g., ingestible concentration) may be specifically, for example, 0.01 ppt (w / w) to 10 ppb (w / w), 0.1 ppt (w / w) to 1 ppb (w / w), or 1 ppt (w / w) to 100 ppt (w / w).
[0054] The content of 2-methyl-3-furanthiol in the article (eg, ingestible concentration) may be, for example, within the range of the content (eg, ingestible concentration) of the active ingredient in the above-exemplified articles. The content of 2-methyl-3-furanthiol in the article (e.g., ingestion concentration) is, for example, 0.01 ppt (w / w) or more, 0.02 ppt (w / w) or more, 0.05 ppt (w / w) or more, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, 0.5 ppt (w / w) or more, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, or 500 ppb(w / w) or more, but not more than 1 ppm(w / w), not more than 500 ppb(w / w). Lower, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less The concentration of ppt(w / w) or less may be 5 ppt(w / w) or less, 2 ppt(w / w) or less, 1 ppt(w / w) or less, 0.5 ppt(w / w) or less, 0.2 ppt(w / w) or less, 0.1 ppt(w / w) or less, 0.05 ppt(w / w) or less, or 0.02 ppt(w / w) or less, or any non-consistent combination thereof. The content of 2-methyl-3-furanthiol in an article (e.g., ingestible concentration) is specifically, for example, 0.01 ppt(w / w) to 0.02 ppt(w / w), 0.02 ppt(w / w) to 0.05 ppt(w / w), 0.05 ppt(w / w) to 0.1 ppt(w / w), 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w) to 10 ppb(w / w), 10 ppb(w / w) to 20 ppb(w / w), 20 ppb(w / w) to 50 ppb(w / w), 50 ppb(w / w) to 100 ppb(w / w), 100 ppb(w / w) to 200 ppb(w / w), 200 ppb(w / w) to 500 ppb(w / w), or 500 ppb(w / w) to 1 ppm(w / w). The content of 2-methyl-3-furanthiol in the article (e.g., ingestible concentration) may be specifically, for example, 0.01 ppt (w / w) to 1 ppm (w / w), 0.1 ppt (w / w) to 100 ppb (w / w), or 1 ppt (w / w) to 10 ppb (w / w).
[0055] The content of 2,5-dimethyl-3-furanthiol in the article (eg, ingestible concentration) may be, for example, within the range of the content (eg, ingestible concentration) of the active ingredient in the above-exemplified articles. The content (e.g., ingestion concentration) of 2,5-dimethyl-3-furanthiol in the article may be, for example, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, 0.5 ppt (w / w) or more, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, or 50 ppb (w / w) or more, and may be, for example, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, 2 ppt(w / w) or less, 1 ppt(w / w) or less, 0.5 ppt(w / w) or less, or 0.2 ppt (w / w) or less, or any compatible combination thereof. The content of 2,5-dimethyl-3-furanthiol in an article (e.g., ingestible concentration) is specifically, for example, 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 The content of 2,5-dimethyl-3-furanthiol in the article (e.g., ingestible concentration) may be, for example, 0.1 ppt(w / w) to 100 ppb(w / w), 1 ppt(w / w) to 10 ppb(w / w), or 10 ppt(w / w) to 1 ppb(w / w).
[0056] The content of methyl linolenate in the article (eg, ingested concentration) may be, for example, within the range of the content of the active ingredient (eg, ingested concentration) in the above-exemplified articles. The content of methyl linolenate in the article (e.g., ingestion concentration) is, for example, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, 0.5 ppt (w / w) or more, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 It may be ppb (w / w) or more, 500 ppb (w / w) or more, 1 ppm (w / w) or more, 2 ppm (w / w) or more, or 5 ppm (w / w) or more, and may be 10 ppm (w / w) or less, 5 ppm (w / w) or less, 2 ppm (w / w) or less, 1 ppm (w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w) The amount of ppt(w / w) or less may be 200 ppt(w / w), 100 ppt(w / w), 50 ppt(w / w), 20 ppt(w / w), 10 ppt(w / w), 5 ppt(w / w), 2 ppt(w / w), 1 ppt(w / w), 0.5 ppt(w / w), or 0.2 ppt(w / w), or any combination thereof that is not contradictory. The content of methyl linolenate in the article (e.g., ingestible concentration) is specifically, for example, 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w) to 5 ppm(w / w), or 5 ppm(w / w) to 10 ppm(w / w) The content of methyl linolenate in the article (e.g., ingestible concentration) may specifically be, for example, 0.1 ppt (w / w) to 10 ppm (w / w), 1 ppt (w / w) to 1 ppm (w / w), or 10 ppt (w / w) to 100 ppb (w / w).
[0057] The content (e.g., ingested concentration) of 3,5-dichlorophenol, phenethyl isothiocyanate, capsaicin, or pepper seed oil (PEPPER OIL BLACK) in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article. In addition, the content (e.g., ingested concentration) of 3,5-dichlorophenol, phenethyl isothiocyanate, capsaicin, or pepper seed oil (PEPPER OIL BLACK) in the article may be, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, or 10 ppt (w / w) or more. , 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, or 500 ppb(w / w) or more; and 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, or any compatible combination thereof. The content (e.g., ingested concentration) of 3,5-dichlorophenol, phenethyl isothiocyanate, capsaicin, or pepper seed oil (PEPPER OIL BLACK) in the food product is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w) to 10 ppb(w / w), 10 ppb(w / w) to 20 ppb(w / w), 20 ppb(w / w) to 50 ppb(w / w), 50 ppb(w / w) to 100 ppb(w / w), 100 ppb(w / w) to 200 ppb(w / w), 200 ppb(w / w) to 500 ppb(w / w), or 500 ppb(w / w) to 1 ppm(w / w). The content (e.g., ingestible concentration) of 3,5-dichlorophenol, phenethyl isothiocyanate, capsaicin, or pepper seed oil (PEPPER OIL BLACK) in the article may be specifically, for example, 1 ppt (w / w) to 1 ppm (w / w), 10 ppt (w / w) to 100 ppb (w / w), or 100 ppt (w / w) to 10 ppb (w / w).
[0058] The content (e.g., ingested concentration) of carvacrol or tridecylic acid in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-mentioned example article. In addition, the content (e.g., ingested concentration) of carvacrol or tridecylic acid in the article may be, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, or 10 ppt (w / w) or more. , 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more or more, 1 ppm (w / w) or more, 2 ppm (w / w) or more, or 5 ppm (w / w) or more, and may be 10 ppm (w / w) or less, 5 ppm (w / w) or less, 2 ppm (w / w) or less, 1 ppm (w / w) or less, 500 ppb (w / w) or less, 200 ppb (w / w) or less, 100 ppb (w / w) or less, 50 ppb (w / w) or less, 20 ppb (w / w) or less, 10 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w) or less, 200 ppt (w / w) or less, 100 ppt (w / w) or less, 50 ppt (w / w) or less, 20 ppt (w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, or any compatible combination thereof. The content of carvacrol or tridecylic acid in the article (e.g., ingestible concentration) may be specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w) to 10 ppb(w / w), 10 ppb(w / w) to 20 ppb(w / w), 20 ppb(w / w) to 50 ppb(w / w), 50 ppb(w / w) to 100 ppb(w / w), 100 ppb(w / w) to 200 ppb(w / w), 200 ppb(w / w) to 500 ppb(w / w), 500 ppb(w / w) to 1 ppm(w / w), 1 ppm(w / w) to 2 ppm(w / w), 2 ppm(w / w) to 5 ppm(w / w), or 5 ppm(w / w) to 10 ppm(w / w). The amount (e.g., ingestible concentration) may be specifically, for example, 1 ppt (w / w) to 10 ppm (w / w), 10 ppt (w / w) to 1 ppm (w / w), or 100 ppt (w / w) to 100 ppb (w / w).
[0059] The content (e.g., ingested concentration) of 1-phenyl-1,3-butanedione or methylheptadienone in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article. The content (e.g., ingested concentration) of 1-phenyl-1,3-butanedione or methylheptadienone in the article may be, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, or 1 ppb (w / w) or more. , 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, or 50 ppm(w / w) or more, and may be 100 ppm (w / w) or less, 50 ppm (w / w) or less, 20 ppm (w / w) or less, 10 ppm (w / w) or less, 5 ppm (w / w) or less, 2 ppm (w / w) or less, 1 ppm (w / w) or less, 500 ppb (w / w) or less, 200 ppb (w / w) or less, 100 ppb (w / w) or less, 50 ppb (w / w) or less, 20 ppb (w / w) or less, 10 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w) or less, 200 ppt (w / w) or less, 100 ppt (w / w) or less, 50 ppt (w / w) or less, 20 ppt (w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, or any compatible combination thereof. The content (e.g., ingestible concentration) of 1-phenyl-1,3-butanedione or methylheptadienone in the article may be specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 The content (e.g., ingestible concentration) of 1-phenyl-1,3-butanedione or methylheptadienone in the article may be, specifically, for example, 1 ppt(w / w) to 100 ppm(w / w), 10 ppt(w / w) to 10 ppm(w / w), or 100 ppt(w / w) to 1 ppm(w / w).
[0060] The content (e.g., ingested concentration) of methyl isothiocyanate or sclareol in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article. The content (e.g., ingestion concentration) is, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more , 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 ppb (w / w) or more, 1 ppm (w / w) or more, 2 ppm (w / w) or more, 5 ppm (w / w) or more, 10 ppm (w / w) or more, 20 ppm (w / w) or more, 50 ppm (w / w) or more, 100 ppm (w / w) or more, 200 ppm (w / w) or more, or 500 ppm (w / w) or more, and may be 1000 ppm (w / w) or less, 500 ppm (w / w) or less, 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less , 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, or any non-consistent combination thereof. The content of methyl isothiocyanate or sclareol in the article (e.g., ingestible concentration) may be, specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w). , 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), 50 The content (e.g., ingested concentration) of methyl isothiocyanate or sclareol in the article may be, for example, 1 ppt(w / w) to 1000 ppm(w / w), 10 ppt(w / w) to 100 ppm(w / w), or 100 ppt(w / w) to 10 ppm(w / w). This is also possible.
[0061] The content (e.g., ingestion concentration) of the active ingredient (E)-β-damascenone, 1,5-pentanedial, 1-pentan-3-one, 3-mercapto-1-hexanol, ethyl gallate, ethyl isothiocyanate, magnolol, or β-elemene in the article may be, for example, in the range of the content (e.g., ingestion concentration) of the active ingredient in the article exemplified above. In addition, the content (e.g., ingestion concentration) of (E)-β-damascenone, 1,5-pentanedial, 1-pentan-3-one, 3-mercapto-1-hexanol, ethyl gallate, ethyl isothiocyanate, magnolol, or β-elemene in the article is, for example, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 It may be ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, or 5 ppm(w / w) or more, and may be 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, or 20 ppt(w / w) or less The content (e.g., ingested concentration) of (E)-β-damascenone, 1,5-pentanedial, 1-pentan-3-one, 3-mercapto-1-hexanol, ethyl gallate, ethyl isothiocyanate, magnolol, or β-elemene in the article may be, for example, 10 ppt (w / w) or less. ~20 ppt(w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 p pb(w / w), 20 ppb(w / w) to 50 ppb(w / w), 50 ppb(w / w) to 100 ppb(w / w), 100 ppb(w / w) to 200 ppb(w / w), 200 ppb(w / w) to 500 ppb(w / w), 500 ppb(w / w) to 1 ppm(w / w), 1 ppm(w / w) to 2 ppm(w / w), 2 ppm(w / w) to 5 ppm(w / w), or 5 ppm(w / w) to 10 ppm(w / w). The content (e.g., ingestion concentration) of (E)-β-damascenone, 1,5-pentanedial, 1-pentan-3-one, 3-mercapto-1-hexanol, ethyl gallate, ethyl isothiocyanate, magnolol, or β-elemene in the product may be specifically, for example, 10 ppt (w / w) to 10 ppm (w / w), 100 ppt (w / w) to 1 ppm (w / w), or 1 ppb (w / w) to 100 ppb (w / w).
[0062] The content of propyl gallate in the article (e.g., ingestible concentration) may be, for example, in the range of the content of the active ingredient in the above-exemplified article (e.g., ingestible concentration). In addition, the content of propyl gallate in the article (e.g., ingestible concentration) may be, for example, 10 ppt (w / w) or more. , 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more or more than 1 ppm (w / w), 2 ppm (w / w), 5 ppm (w / w), 10 ppm (w / w), 20 ppm (w / w), 50 ppm (w / w), 100 ppm (w / w), 200 ppm (w / w), or 500 ppm (w / w) or less, and may be 1000 ppm (w / w), 500 ppm (w / w), 200 ppm (w / w), 100 ppm (w / w), 50 ppm (w / w), 20 ppm (w / w), 10 ppm (w / w), 5 ppm (w / w), 2 ppm (w / w), 1 ppm (w / w), 500 ppb (w / w), 200 ppb (w / w), 100 ppb (w / w), 50 ppb (w / w), 20 ppb (w / w), 10 ppb (w / w), 5 ppb (w / w), 2 ppb (w / w), 1 ppb (w / w), 500 ppt (w / w), 200 ppt (w / w), 100 ppt(w / w) or less, 50 ppt(w / w) or less, or 20 ppt(w / w) or less, or any compatible combination thereof. The content of propyl gallate in the article (e.g., ingestible concentration) may be, for example, 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) ~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), 50 ppm(w / w)~100 The content of propyl gallate in the article (e.g., the amount of propyl gallate consumed) may be 100 ppm (w / w) to 200 ppm (w / w), 200 ppm (w / w) to 500 ppm (w / w), or 500 ppm (w / w) to 1000 ppm (w / w). The concentration) may be specifically, for example, 10 ppt (w / w) to 1000 ppm (w / w), 100 ppt (w / w) to 100 ppm (w / w), or 1 ppb (w / w) to 10 ppm (w / w).
[0063] The content (e.g., ingested concentration) of 2,6-dichlorobenzaldehyde, apigenin, β-caryophyllene, or N-(4-hydroxy-3-methoxybenzyl)nonanamide in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the article exemplified above. In addition, the content (e.g., ingestion concentration) of 2,6-dichlorobenzaldehyde, apigenin, β-caryophyllene, or N-(4-hydroxy-3-methoxybenzyl)nonanamide in the article is, for example, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 It may be ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, or 50 ppm(w / w) or more, and may be 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w) or less, or 200 ppt (w / w) or less, any combination thereof that is not inconsistent. A combination is also acceptable. The content (e.g., ingestible concentration) of 2,6-dichlorobenzaldehyde, apigenin, β-caryophyllene, or N-(4-hydroxy-3-methoxybenzyl)nonanamide in the article is specifically, for example, 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w) to 10 ppb(w / w), 10 ppb(w / w) to 20 ppb(w / w), 20 ppb(w / w) to 50 ppb(w / w), 50 ppb(w / w) to 100 ppb(w / w), 100 ppb(w / w)-200 ppb(w / w), 200 ppb(w / w)-500 ppb(w / w), 500 ppb(w / w)-1 ppm(w / w), 1 ppm(w / w)-2 ppm(w / w), 2 ppm(w / w)-5 ppm(w / w), 5 ppm(w / w)-10 ppm(w / w), 10 ppm(w / w)-20 ppm(w / w), 20 ppm(w / w)-50 ppm(w / w), or 50 ppm(w / w)-100 ppm(w / w). The content (e.g., ingestible concentration) of 2,6-dichlorobenzaldehyde, apigenin, β-caryophyllene, or N-(4-hydroxy-3-methoxybenzyl)nonanamide in the article may be specifically, for example, 100 ppt (w / w) to 100 ppm (w / w), 1 ppb (w / w) to 10 ppm (w / w), or 10 ppb (w / w) to 1 ppm (w / w).
[0064] The concentration of the active ingredient in the article (e.g., the concentration when consumed) may be, for example, 100 times or less than the threshold concentration of the active ingredient, 10 times or less than the threshold concentration, 5 times or less than the threshold concentration, 2 times or less than the threshold concentration, or less than the threshold concentration. The concentration of the active ingredient in the article (e.g., the concentration when consumed) may be, for example, in the range of the concentration of the active ingredient in the above-mentioned example (e.g., the concentration when consumed), and may be, for example, in the range of 100 times or less than the threshold concentration of the active ingredient, 10 times or less than the threshold concentration, 5 times or less than the threshold concentration, 2 times or less than the threshold concentration, or less than the threshold concentration. The "threshold concentration of the active ingredient" means the maximum concentration of the active ingredient at which the odor of the active ingredient itself is not felt when an aqueous solution containing the active ingredient alone is consumed or sniffed with the nose. The threshold concentration of the active ingredient may be the threshold concentration described in the examples.
[0065] The description of the addition of an active ingredient can be applied mutatis mutandis to the addition of the composition of the present invention. For example, the composition of the present invention can be added so as to obtain the amount of the active ingredient exemplified above.
[0066] Ingredients other than the active ingredient may be added to the raw materials of the product, for example, so that the ingested concentration of the ingredients other than the active ingredient falls within a desired range (for example, the range described below).
[0067] The article of the present invention may contain a component capable of producing 2,6-dimethylpyridine. That is, the article of the present invention may be manufactured so as to contain a component capable of producing 2,6-dimethylpyridine. The article containing a component capable of producing 2,6-dimethylpyridine can be manufactured, for example, using a material containing a component capable of producing 2,6-dimethylpyridine. That is, the method of the present invention may further include manufacturing the article using a material containing a component capable of producing 2,6-dimethylpyridine. That is, examples of raw materials for the article include materials containing a component capable of producing 2,6-dimethylpyridine. In other words, the raw materials for the article may contain a component capable of producing 2,6-dimethylpyridine. The materials containing a component capable of producing 2,6-dimethylpyridine are as described above.
[0068] When a component capable of generating 2,6-dimethylpyridine can form a salt, the component capable of generating 2,6-dimethylpyridine may be used as a free form, as a salt, or as a combination thereof. That is, unless otherwise specified, the term "component capable of generating 2,6-dimethylpyridine" may mean a component capable of generating 2,6-dimethylpyridine in a free form, or a salt thereof, or a combination thereof. "Free form" means a form that does not form a salt. In addition, when a component capable of generating 2,6-dimethylpyridine can form a hydrate, the component capable of generating 2,6-dimethylpyridine may be used as a non-hydrate, as a hydrate, or as a combination thereof. That is, the term "component capable of generating 2,6-dimethylpyridine" may be used as a non-hydrate, as a hydrate, or as a combination thereof. Terms (e.g., "a component capable of generating 2,6-dimethylpyridine in a free form" or "a salt of a component capable of generating 2,6-dimethylpyridine") may include non-hydrates and hydrates unless otherwise specified. The component capable of generating 2,6-dimethylpyridine may be in any form, such as an ion, during use of the article.
[0069] The salt is not particularly limited as long as it is acceptable according to the purpose of the present invention. For example, when the subject is food, the salt is not particularly limited as long as it is orally ingestible. For example, the salt of an acidic group such as a carboxyl group specifically includes ammonium salts, salts with alkali metals such as sodium and potassium, salts with alkaline earth metals such as calcium and magnesium, aluminum salts, zinc salts, salts with organic amines such as triethylamine, ethanolamine, morpholine, pyrrolidine, piperidine, piperazine, and dicyclohexylamine, and salts with basic amino acids such as arginine and lysine. Furthermore, specific examples of salts with basic groups such as amino groups include salts with inorganic acids such as hydrochloric acid, sulfuric acid, phosphoric acid, nitric acid, and hydrobromic acid, salts with organic carboxylic acids such as acetic acid, citric acid, benzoic acid, maleic acid, fumaric acid, tartaric acid, succinic acid, tannic acid, butyric acid, hybenzic acid, pamoic acid, enanthic acid, decanoic acid, teoclic acid, salicylic acid, lactic acid, oxalic acid, mandelic acid, malic acid, methylmalonic acid, and adipic acid, and salts with organic sulfonic acids such as methanesulfonic acid, benzenesulfonic acid, and p-toluenesulfonic acid. As the salt, one type of salt may be used, or two or more types of salts may be used in combination.
[0070] When a material containing a component capable of producing 2,6-dimethylpyridine is used, the amount of the component capable of producing 2,6-dimethylpyridine (e.g., content (concentration) or usage amount) is calculated based on the amount of the component itself capable of producing 2,6-dimethylpyridine in the material. When a component capable of producing 2,6-dimethylpyridine forms a salt or hydrate, the amount of the component capable of producing 2,6-dimethylpyridine (e.g., content (concentration) or usage amount) is calculated based on the value obtained by converting the mass of the salt or hydrate into the equimolar mass of the unhydrated free form.
[0071] The article of the present invention may contain 2,6-dimethylpyridine. That is, the article of the present invention may be manufactured to contain 2,6-dimethylpyridine. The article containing 2,6-dimethylpyridine can be manufactured, for example, using a material containing 2,6-dimethylpyridine. That is, the method of the present invention may further include manufacturing the article using a material containing 2,6-dimethylpyridine. That is, the raw material of the article may be a material containing 2,6-dimethylpyridine. In other words, the raw material of the article may contain 2,6-dimethylpyridine. The material containing 2,6-dimethylpyridine is as described above. In addition, 2,6-dimethylpyridine may be generated, for example, during the manufacturing process of the article of the present invention. In addition, 2,6-dimethylpyridine may be generated, for example, after the manufacturing process of the article of the present invention is carried out (for example, during storage of the article of the present invention). 2,6-dimethylpyridine may be generated from a component that can generate 2,6-dimethylpyridine.
[0072] In addition, when a material containing 2,6-dimethylpyridine is used, the amount of 2,6-dimethylpyridine (e.g., content (concentration) or amount used) is to be calculated based on the amount of 2,6-dimethylpyridine itself in the material.
[0073] When the article of the present invention contains a component capable of producing 2,6-dimethylpyridine, the content of the component capable of producing 2,6-dimethylpyridine in the article of the present invention may be, for example, an amount capable of producing 2,6-dimethylpyridine at which a human detects the odor of 2,6-dimethylpyridine (for example, an ingestible concentration). When the article of the present invention contains two or more types of components capable of producing 2,6-dimethylpyridine, the content of the component capable of producing 2,6-dimethylpyridine in the article of the present invention may be, for example, an amount capable of producing 2,6-dimethylpyridine at which a human detects the odor of 2,6-dimethylpyridine (for example, an ingestible concentration). "The content of the components that can be generated is an amount that can produce 2,6-dimethylpyridine in an amount that causes a human to detect a 2,6-dimethylpyridine odor (e.g., an ingestion concentration)" means that the total amount of 2,6-dimethylpyridine that can be generated from those two or more components (e.g., a total ingestion concentration) is an amount that causes a human to detect a 2,6-dimethylpyridine odor (e.g., an ingestion concentration). "Humans detect a 2,6-dimethylpyridine odor" may mean, for example, in the case of a retronasal aroma, that the 2,6-dimethylpyridine odor is detected when the article of the present invention is consumed. "Humans detect a 2,6-dimethylpyridine odor" may mean, for example, in the case of an orthonasal aroma, that the 2,6-dimethylpyridine odor is detected when the article of the present invention is smelled with the nose.
[0074] When the article of the present invention contains a component capable of producing 2,6-dimethylpyridine, the content of the component capable of producing 2,6-dimethylpyridine in the article of the present invention (e.g., ingestible concentration) is, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more. , 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 ppb (w / w) or more, 1 ppm (w / w) or more, 2 ppm (w / w) or more, 5 ppm (w / w) or more, 10 ppm (w / w) or more, 20 ppm (w / w) or more, 50 ppm (w / w) or more, 100 ppm (w / w) or more, 200 ppm (w / w) or more, 500 ppm (w / w) or more, 1000 ppm (w / w) or more, 2000 ppm (w / w) or more, or 5000 ppm (w / w) or more, ppm(w / w) Below, 5000 ppm (w / w) or less, 2000 ppm (w / w) or less, 1000 ppm (w / w) or less, 500 ppm (w / w) or less , 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, or any compatible combination thereof. The content (e.g., ingestion concentration) of the component capable of generating 2,6-dimethylpyridine in the article of the present invention may be specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w) , 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 The content of the cellulose in the article of the present invention may be from 1 ppm (w / w) to 10 ppm (w / w), from 10 ppm (w / w) to 20 ppm (w / w), from 20 ppm (w / w) to 50 ppm (w / w), from 50 ppm (w / w) to 100 ppm (w / w), from 100 ppm (w / w) to 200 ppm (w / w), from 200 ppm (w / w) to 500 ppm (w / w), from 500 ppm (w / w) to 1000 ppm (w / w), from 1000 ppm (w / w) to 2000 ppm (w / w), from 2000 ppm (w / w) to 5000 ppm (w / w), or from 5000 ppm (w / w) to 10000 ppm (w / w). The content (e.g., ingestible concentration) of the component capable of producing 2,6-dimethylpyridine may be, specifically, for example, 1 ppt (w / w) to 10,000 ppm (w / w). When an article contains two or more components capable of producing 2,6-dimethylpyridine, the contents (e.g., ingestible concentration) of the two or more components capable of producing 2,6-dimethylpyridine in the article may be set independently or in total within the range of the contents (e.g., ingestible concentration) of the components capable of producing 2,6-dimethylpyridine in the above-exemplified article. In addition, when an article contains two or more components capable of producing 2,6-dimethylpyridine, the "content of the component capable of producing 2,6-dimethylpyridine in the article" means the total content of the two or more components capable of producing 2,6-dimethylpyridine in the article, unless otherwise specified. In addition, when a food product contains two or more ingredients that can produce 2,6-dimethylpyridine, the "concentration of ingredients that can produce 2,6-dimethylpyridine" refers to the concentration of those two or more 2,6-dimethylpyridine in the food product, unless otherwise specified. "glutinin" means the total consumption concentration of ingredients that can give rise to gin.
[0075] When the article of the present invention contains 2,6-dimethylpyridine, the content of 2,6-dimethylpyridine in the article of the present invention (e.g., ingestible concentration) may be, for example, an amount at which a human senses the 2,6-dimethylpyridine odor (e.g., ingestible concentration). The amount of 2,6-dimethylpyridine at which a human senses the 2,6-dimethylpyridine odor (e.g., ingestible concentration) is as described above.
[0076] When the article of the present invention contains 2,6-dimethylpyridine, the content of 2,6-dimethylpyridine in the article of the present invention (e.g., ingestible concentration) is, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more. or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 It may be 10000 ppm(w / w) or less, 5000 ppm(w / w) or less, 2000 ppm(w / w) or more, 10000 ppm(w / w) or less, 2000 ppm(w / w) or more, or 5000 ppm(w / w) or more, or 100000 ppm(w / w) or less, 5000 ppm(w / w) or less, 2000 ppm(w / w) or less, 1000 ppm(w / w) or less, 500 ppm(w / w) or less, 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less , 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) The following may be used, or any non-consistent combination thereof: The content of 2,6-dimethylpyridine in the article of the present invention (e.g., ingestible concentration) is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppm(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 The content of 2,6-dimethylpyridine in the article of the present invention (e.g., ingested concentration) may be, specifically, 1 ppt(w / w) to 10000 ppm(w / w). The content of 2,6-dimethylpyridine in the article of the present invention (e.g., ingested concentration) may be, specifically, 1 ppt(w / w) to 10000 ppm(w / w).
[0077] When the article of the present invention contains 2,6-dimethylpyridine and / or components capable of producing 2,6-dimethylpyridine, the total content of 2,6-dimethylpyridine and / or components capable of producing 2,6-dimethylpyridine in the article of the present invention (e.g., total consumption concentration) is, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more. , 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 ppb (w / w) or more, 1 ppm (w / w) or more, 2 ppm (w / w) or more, 5 ppm (w / w) or more, 10 ppm (w / w) or more, 20 ppm (w / w) or more, 50 ppm (w / w) or more, 100 ppm (w / w) or more, 200 ppm (w / w) or more, 500 ppm (w / w) or more, 1000 ppm (w / w) or more, 2000 ppm (w / w) or more, or 5000 ppm (w / w) or more, ppm(w / w) Below, 5000 ppm (w / w) or less, 2000 ppm (w / w) or less, 1000 ppm (w / w) or less, 500 ppm (w / w) or less , 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w) or less, 500 ppb (w / w), 200 ppb (w / w), 100 ppb (w / w), 50 ppb (w / w), 20 ppb (w / w), 10 ppb (w / w), 5 ppb (w / w), 2 ppb (w / w), 1 ppb (w / w), 5 ppb (w / w), 2 ppb (w / w), 1 ppb (w / w), 500 ppt (w / w), 200 ppt (w / w), 100 ppt (w / w), 50 ppt (w / w), 20 ppt (w / w), 10 ppt (w / w), 5 ppt (w / w), or 2 ppt (w / w), or any non-consistent combination thereof. This is also possible. The total content of 2,6-dimethylpyridine and / or components capable of producing 2,6-dimethylpyridine in the article of the present invention (e.g., total ingested concentration) is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w) to 50 ppm(w / w), 50 ppm(w / w) to 100 ppm(w / w), 100 ppm(w / w) to 200 ppm(w / w), 200 ppm(w / w) to 500 ppm(w / w), 500 ppm(w / w) to 1000 ppm(w / w), 1000 ppm(w / w) to 2000 ppm(w / w), 2000 ppm(w / w) to 5000 ppm(w / w), or 5000 ppm(w / w) to 10000 ppm(w / w). The total content (e.g., total consumption concentration) of 2,6-dimethylpyridine and / or components capable of producing 2,6-dimethylpyridine in the article of the present invention may be specifically, for example, 1 ppt(w / w) to 10000 ppm(w / w).
[0078] Also, for example, the active ingredient can be used to suppress the 2,6-dimethylpyridine odor by contacting it with an article such as waste. That is, the use of the active ingredient (specifically, application of the active ingredient to a target) can include contacting the active ingredient with an article such as waste. That is, the method of the present invention can specifically be, for example, a method for suppressing the 2,6-dimethylpyridine odor in an article such as waste, including contacting the active ingredient with an article such as waste. The active ingredient can be contacted with an article such as waste as it is, or after being appropriately prepared into a desired form such as a solution. For example, the active ingredient in any form such as a solution can be mixed with an article such as waste, a solution containing the active ingredient can be sprayed onto an article such as waste, or an article such as waste can be immersed in a solution containing the active ingredient.
[0079] Also, for example, the active ingredient can be used to suppress the 2,6-dimethylpyridine odor by applying it to a space. That is, the use of the active ingredient (specifically, application of the active ingredient to a target) can be, for example, applying the active ingredient to a space. That is, the method of the present invention can be, specifically, for example, a method for suppressing the 2,6-dimethylpyridine odor in a space, including applying the active ingredient to the space. The active ingredient can be applied to the space as it is, or after being appropriately prepared into a desired form such as a solution. For example, a solution containing the active ingredient can be sprayed into the space.
[0080] When the active ingredient is brought into contact with an article such as waste or when the active ingredient is applied to a space, the concentration of the active ingredient in the solution containing the active ingredient is not particularly limited as long as a masking effect can be obtained. The concentration of the active ingredient in the solution containing the active ingredient may be set, for example, within the range of the content of the active ingredient in the composition of the present invention exemplified above. The concentration of the active ingredient in the solution containing the active ingredient may be set, for example, within the range of the content of the active ingredient in the article exemplified above (for example, the concentration for consumption). The concentration of the active ingredient in the solution containing the active ingredient may be, for example, 1 or more, 2 or more, 5 or more, 10 or more, 20 or more, 50 or more, 100 or more, 200 or more, or 500 or more times the content of the active ingredient in the article exemplified above (for example, the concentration for consumption), and may be 1000 or less, 500 or less, 200 or less, 100 or less, 50 or less, 20 or less, 10 or less, 5 or less, or 2 or less. The active ingredient may be present in a concentration of 100 mg / kg or a combination thereof that is not inconsistent with the active ingredient. Specifically, the concentration of the active ingredient in the composition may be, for example, 1 to 2 times, 2 to 5 times, 5 to 10 times, 10 to 20 times, 20 to 50 times, 50 to 100 times, 100 to 200 times, 200 to 500 times, or 500 to 1000 times the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article.
[0081] When the active ingredient is brought into contact with an article such as waste or applied to a space, the amount of the active ingredient used is not particularly limited as long as a masking effect can be obtained. The amount of the active ingredient used may be set, for example, so that the content of the active ingredient in a mixture of the active ingredient and waste falls within the range of the content of the active ingredient in the above-mentioned example article. The amount of the active ingredient used may be, for example, the amount of solution containing the active ingredient (for example, a solution containing the active ingredient at a concentration as exemplified above) used (for example, a spray amount) per 1 kg of an article or per m of space. 3 per unit, 0.1 mL or more, 0.2 mL or more, 0.5 mL or more, 1 mL or more, 2 mL or more, 5 mL or more, 10 mL or more, The amount of the active ingredient may be, for example, the amount of the solution containing the active ingredient (for example, the solution containing the active ingredient at the concentration exemplified above) used (e.g., spray amount) per 1 kg of the article or per m of space, or may be 50 mL or less, 20 mL or less, 10 mL or less, 5 mL or less, 2 mL or less, 1 mL or less, 0.5 mL or less, or 0.2 mL or less, or any combination thereof that is compatible with the above. 3 per mL, 0.1-0.2 mL, 0.2-0.5 mL, 0.5 It may be ~1 mL, 1-2 mL, 2-5 mL, 5-10 mL, 10-20 mL, or 20-50 mL.
[0082] <4> Use of active ingredients The present invention also discloses the use of the active ingredient in the above-exemplified applications, i.e., for example, the use of the active ingredient for suppressing the 2,6-dimethylpyridine odor or for producing an article such as food, and the use of the active ingredient in producing a composition for suppressing the 2,6-dimethylpyridine odor or for producing an article such as food.
[0083] The present invention also discloses active ingredients for use in the above-mentioned applications, i.e., active ingredients for use in suppressing the 2,6-dimethylpyridine odor or in producing articles such as food, and active ingredients for use in producing a composition for suppressing the 2,6-dimethylpyridine odor or in producing articles such as food. EXAMPLES
[0084] The present invention will be described in more detail below with reference to non-limiting examples.
[0085] The raw materials, reagents, compounds, and the like used in the present examples are readily available or can be prepared according to methods commonly practiced in the art, or are commercially available, unless otherwise specified.
[0086] [Test Example 1] Scoring method (swallowing evaluation) (Preparation of evaluation samples) In a 35 ppm 2,6-Dimethylpyridine aqueous solution, add each compound shown in Table 1 at the concentration shown in Table 1. The concentration of each compound was determined as the maximum concentration (for convenience of explanation, this is referred to as the "threshold concentration") at which the odor of the compound itself was not felt when an aqueous solution containing each compound alone was held in the mouth and swallowed, among the multiple concentrations previously evaluated.
[0087] (Evaluation of 2,6-Dimethylpyridine odor masking effect) The 2,6-Dimethylpyridine odor intensity was evaluated when 5 ml of each evaluation sample was held in the mouth and swallowed naturally. The 2,6-Dimethylpyridine odor intensity was scored in the range of 0 to 5 points according to the following evaluation criteria, based on 2,6-Dimethylpyridine aqueous solutions prepared to 35 ppm, 20 ppm, or 0 ppm. Scoring was performed by a panel of three experts, and the average was calculated for each evaluation sample. The results are shown in Table 1.
[0088] [Evaluation Criteria] 0: 2,6-Dimethylpyridine odor intensity of 0ppm 2,6-Dimethylpyridine aqueous solution (water without added 2,6-Dimethylpyridine) 3: 2,6-Dimethylpyridine odor intensity of 20 ppm 2,6-Dimethylpyridine aqueous solution 5: 2,6-Dimethylpyridine odor intensity of 35 ppm 2,6-Dimethylpyridine aqueous solution
[0089] [Masking effect evaluation criteria] - : 2,6-Dimethylpyridine odor intensity is 5.2 or more ± : 2,6-Dimethylpyridine odor intensity is 4.8 or more and less than 5.2 +: 2,6-Dimethylpyridine odor intensity is 4.0 or more and less than 4.8 ++: 2,6-Dimethylpyridine odor intensity is 3 or more but less than 4 +++: 2,6-Dimethylpyridine odor intensity is less than 3 (same intensity as 2,6-Dimethylpyridine at 20 ppm)
[0090] The results are shown in Table 1. All of the compounds shown in Table 1 exhibited a 2,6-Dimethylpyridine odor masking effect.
[0091] [Table 1]
[0092] [Test Example 2] 2-AFC method (swallowing evaluation) (Preparation of evaluation samples) Each compound shown in Table 2 was added to a 35 ppm 2,6-Dimethylpyridine aqueous solution at the concentrations shown in Table 2. The concentration of each compound was determined as the maximum concentration (for convenience of explanation, this is referred to as the "threshold concentration") at which the odor of the compound itself was not felt when an aqueous solution containing each compound alone was held in the mouth and swallowed, among the multiple concentrations previously evaluated.
[0093] (Evaluation of 2,6-Dimethylpyridine odor masking effect) 5 ml of the evaluation sample was placed in the mouth and swallowed naturally, and the strength of the 2,6-Dimethylpyridine odor of the evaluation sample was evaluated in comparison with the control (35 ppm 2,6-Dimethylpyridine aqueous solution). The evaluation was carried out by a panel of three experts, and if two or more (66.7% or more) of the panel judged the masking effect to be "weak," it was determined that there was a masking effect.
[0094] The results are shown in Table 2. All of the compounds shown in Table 2 were 2,6-Dimethylpyridine odor masking compounds. The results showed a positive effect.
[0095] [Table 2]
[0096] [Test Example 3] 2-AFC method (smelling evaluation) (Preparation of evaluation samples) A propylene glycol (PG) solution containing 500 ppm 2,6-Dimethylpyridine was prepared as a control solution. A PG solution containing each compound shown in Table 3 at the concentration shown in Table 3 was prepared as a compound solution. A cotton ball containing 10 μl of the control solution was placed in a 110 ml bottle, the bottle was closed with a lid, and the control was used. A cotton ball containing 10 μl of the control solution and 10 μl of the compound solution was placed in a 110 ml bottle, the bottle was closed with a lid, and the evaluation sample was used. After 5 hours or more had passed, the odor evaluation was performed. The concentration of each compound was determined as the maximum concentration (for convenience of explanation, this is referred to as the "threshold") at which the odor of the compound itself was not felt when a cotton ball containing each compound dissolved in a PG solution alone was placed in a 110 ml bottle, the bottle was closed, and the odor was smelled after 5 hours or more had passed.
[0097] (Evaluation of 2,6-Dimethylpyridine odor masking effect) The lid of each bottle was opened, and the strength of the 2,6-Dimethylpyridine odor of the evaluation sample was evaluated against the control when the odor was smelled. The evaluation was carried out by a panel of three experts, and if two or more panelists (66.7% or more) judged the odor to be "weak," it was determined that there was a masking effect.
[0098] The results are shown in Table 3. All of the compounds shown in Table 3 exhibited a 2,6-Dimethylpyridine odor masking effect.
[0099] [Table 3]
Claims
1. A composition for suppressing the odor of 2,6-dimethylpyridine in a subject, comprising: A composition comprising the following component (A): (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde.
2. The composition of claim 1 , wherein the object is an object or a space.
3. The composition of claim 2 , wherein the item is food or waste.
4. A composition for the manufacture of an article, comprising: A composition comprising the following component (A): (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde.
5. The composition of claim 4 , wherein the article is a food product.
6. The composition according to claim 4 or 5, wherein the article is an article in which the odor of 2,6-dimethylpyridine is suppressed.
7. The composition according to any one of claims 2 to 4, wherein the article contains 2,6-dimethylpyridine and / or a component capable of producing 2,6-dimethylpyridine.
8. 1. A method for inhibiting 2,6-dimethylpyridine odor in a subject, comprising: A method comprising the step of applying the following component (A) to the subject: (A) Sclareol, (3R / 3S)-3-sulfanylpentan-2-one, 2-methyl-3-furanthiol, magnolol, 3,5-dichlorophenol, tridecylic acid, propyl gallate, ethyl gallate, 1,5-pentanedial, phenethyl isothiocyanate, methylheptadienone, β-elemene, capsaicin, 1-phenyl-1,3-butanedione, methyl isothiocyanate, methyl linoleate, ethyl isothiocyanate, 6-acetyl-1,1,2,4,4,7-hexamethyltetralin, 2,5-di At least one component selected from the group consisting of methyl-3-furanthiol, carvacrol, ethyl mercaptoacetate, pepper seed oil (PEPPER OIL BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and 2,6-dichlorobenzaldehyde.
9. The method of claim 8 , wherein the object is an object or a space.
10. The method of claim 9 , wherein the item is food or waste.
11. The object is an article, The article is a food product, 10. The method of claim 9, wherein said step is adding said component (A) to a raw material of said article.
12. 1. A method of manufacturing an article, comprising the steps of: The method includes the step of adding the following component (A) to a raw material of the article: (A) Sclareol, (3R / 3S)-3-Sulfanylpentan-2-one, 2-Methyl-3-Furanthiol, Magnolol, 3,5-Dichlorophenol, Tridecylic Acid, Propyl Gallate, Ethyl Gallate, 1,5-Pentanedial, Phenethyl Isothiocyanate, Methylheptadienone, β-Element, Capsaicin, 1-Phenyl-1,3-Butanedione, Methyl Isothiocyanate, Methyl Linolenate, Ethyl Isothiocyanate, 6-Acetyl-1,1,2,4,4,7-Hexamethyltetralin, 2,5-Dimethyl-3-Furanthiol, Carvacrol, Ethyl Mercaptoacetate, Pepper Seed Oil BLACK), apigenin, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, (E)-β-damascenone, 3-mercapto-1-hexanol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dichlorobenzaldehyde.
13. The method of claim 12, wherein the item is a food product.
14. The method according to claim 12 or 13, wherein the article is an article in which the odor of 2,6-dimethylpyridine is suppressed.
15. The method according to any one of claims 9 to 13, wherein the article or the raw material contains 2,6-dimethylpyridine and / or a component capable of producing 2,6-dimethylpyridine.
16. The content of the component (A) in the article is 0.001 ppt (w / w) to 1000 ppm (w / w). The method according to any one of claims 9 to 13, wherein the compound is added in the form of
17. The article is a food product, The method according to claim 16, wherein the content is an eating concentration.