Myalgia inhibitory composition and food and drink containing the same

Abstract

To provide a myalgia inhibitor or a myalgia inhibitory functional food that allow daily continuous use, have excellent safety and can reduce and prevent the occurrence of myalgia.SOLUTION: A myalgia inhibitory composition contains citrate. The myalgia inhibitory composition may further comprise citric acid.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a composition for suppressing muscle pain and a food or drink containing the same. The composition for suppressing muscle pain of the present invention and a food or drink containing the same are useful for preventing or suppressing muscle pain associated with exercise. [Background technology]

[0002] In recent years, the number of sports enthusiasts has increased with the rise in health consciousness, and sports are enjoyed by a wide range of age groups, from young children to the elderly. However, sports injuries caused by excessive practice and incorrect training are on the rise and have become a problem. Muscle pain can be considered a type of sports injury, and there are two types: "acute muscle pain" that occurs during or immediately after exercise, and "delayed onset muscle pain" that occurs several to 24 hours after exercise. There are various theories about the mechanism of muscle pain, but the former is thought to be caused by the accumulation of lactic acid and hydrogen ions in the muscles due to intense exercise that puts a strain on the muscles, such as weightlifting and sprinting, which causes a lack of blood flow to some parts of the muscles. On the other hand, the latter is caused by unfamiliar exercise or exercise that does not match one's strength, which causes the muscles to repeatedly contract excessively and become damaged, and "inflammation" occurs to repair the damaged muscle fibers, and stimulating substances (bradykinin, histamine, serotonin, prostaglandins, etc.) are produced, which are transmitted to the central nervous system through the sensory nerves and felt as pain. Muscle pain is not just a problem for humans. For example, in racehorses, muscle pain is an important disease that greatly affects racing performance, and it is known that it has a high possibility of triggering the development of other musculoskeletal diseases such as fractures and tendonitis (Non-Patent Document 1).

[0003] Several substances and foods that have the effect of preventing and improving muscle pain have been developed. For example, Patent Document 1 describes a method for preventing muscle pain by taking ribose. Patent Document 2 describes a muscle pain prevention agent that contains panaxatriol and panaxadiol that have the effect of promoting energy production. Patent Document 3 describes a muscle pain suppressant that contains fermented milk using Lactobacillus helveticus CM4 strain.

[0004] Citric acid is an organic acid found in many citrus fruits and is used as an acidulant in many foods and beverages. Citric acid is a metabolic component in the TCA cycle and has been reported to be effective in fatigue recovery. For example, Patent Document 4 describes liquids and tablets containing citric acid as fatigue improvement agents that contain organic acids or salts thereof having two or more carboxyl groups as active ingredients. Patent Document 5 describes an internal liquid for use during physical fatigue that contains a specified concentration of sucrose and citric acid. Patent Document 6 describes an internal liquid for fatigue recovery that contains a specified concentration of citric acid or one or more salts thereof and royal jelly. However, although these documents describing the health benefits of citric acid mention its fatigue recovery effect, they do not mention its muscle pain suppression effect. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] JP 2015-52018 A [Patent Document 2] JP 2013-139394 A [Patent Document 3] Patent No. 5198865 [Patent Document 4] Japanese Patent Application Publication No. 10-175856 [Patent Document 5] JP 2000-333651 A [Patent Document 6] JP 2001-226272 A [Non-patent literature]

[0006] [Non-Patent Document 1] Toshio Yamaguchi, "Effects of Laser Irradiation on the Movement Disorders of Racehorses - Particularly the Therapeutic Effect on Muscle Pain", Tohoku Livestock Clinical Research Journal, Vol. 17, No. 2, 1994, pp. 76-85 Summary of the Invention [Problem to be solved by the invention]

[0007] The present invention aims to provide a muscle pain suppressant or functional food for suppressing muscle pain, which can be taken continuously on a daily basis, is highly safe, and is capable of alleviating or preventing the occurrence of muscle pain. [Means for solving the problem]

[0008] The present inventors made extensive efforts to elucidate new functionality of citric acid and / or citrates, and surprisingly found that citrates have a muscle pain suppressing effect, leading to the completion of the present invention. According to the present invention, a muscle pain suppressant or functional food for suppressing muscle pain containing citrate as an active ingredient is provided. According to the present invention, there is also provided use of citrate for producing a muscle pain suppressant, particularly a delayed-onset muscle pain suppressant or functional food for suppressing muscle pain. According to the present invention, there is also provided a method for suppressing muscle pain, particularly delayed-onset muscle pain, by administering citrate as an active ingredient.

[0009] The gist of the present invention is [1] A composition for suppressing muscle pain, comprising a citrate salt or a hydrate thereof. [2] The composition according to [1] above, wherein the muscle pain is delayed-onset muscle pain. [3] The composition according to [1] or [2], wherein the citrate is potassium citrate, sodium citrate, or a mixture thereof. [4] The composition according to [3] above, wherein the mixture of citrates contains potassium citrate and sodium citrate in a ratio of 1.00:0.80 to 1.20 (molar ratio calculated on anhydrous basis). [5] The composition according to [3] above, wherein the mixture of citrates contains potassium citrate and sodium citrate in a ratio of 1.00:0.90 to 1.10 (molar ratio in terms of anhydrous substances). [6] The composition according to any one of [1] to [5], further comprising citric acid. [7] The composition according to [6], further comprising sucrose. [8] A food or drink for suppressing muscle pain, comprising the composition according to any one of [1] to [7]. [9] A feed additive or nutritional supplement for a mammal other than human beings for preventing or reducing muscular pain in the mammal other than human beings, comprising the composition according to any one of [1] to [7] above. Regarding. Effect of the Invention

[0010] The muscle pain suppressing composition of the present invention and the food containing the same contain citrate as an active ingredient and can alleviate or prevent the occurrence of muscle pain. Therefore, it is expected that the occurrence of muscle pain can be effectively suppressed by taking the muscle pain suppressing composition of the present invention or the food containing the same, preferably continuously, before performing exercise or the like that may cause muscle pain. [Brief description of the drawings]

[0011] [Figure 1] FIG. 1 shows a diagram of a pain assessment tool. [Diagram 2] FIG. 2 shows the VAS scale actually used in Example 2 as a tool for pain assessment. [Diagram 3] FIG. 3 shows the results of the muscle pain suppression effect in sports enthusiasts who participated in the test of Example 2. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0012] Specific embodiments of the present invention will be described in detail below. However, the present invention is not limited to the following embodiments, and can be implemented with appropriate modifications within the scope of the object of the present invention.

[0013] The composition for suppressing muscle pain of the present invention contains a citrate salt, and further contains other ingredients (e.g., citric acid, sucrose, and other additives) as necessary. In the present invention, "muscle pain" refers to muscle pain caused by exercise. Here, muscle pain that occurs during or immediately after exercise is called "acute muscle pain," and muscle pain that occurs a certain time after exercise is called "delayed onset muscle pain."

[0014] Acute muscle pain is thought to be caused by the accumulation of lactic acid and hydrogen ions in the muscles, resulting from intense exercise such as weightlifting and sprinting, which places a strain on the muscles. Delayed onset muscle pain is thought to be caused by repeated excessive contraction of the muscles due to unfamiliar exercise, exercise that does not match one's strength, or inappropriate training, which damages the muscle fibers. It is thought that pain is received by mechanical stimuli such as increased intramuscular pressure due to the inflammatory reaction that occurs when repairing the damaged muscle fibers, thermal stimuli due to increased muscle temperature, and chemical stimuli due to pain-inducing substances such as bradykinin, serotonin, histamine, prostaglandins, and potassium ions, which act on the free endings of the afferent fibers, Aδ fibers and C fibers.

[0015] In humans, muscle pain can be evaluated by simple methods such as the Visual Analogue Scale (VAS), Verbal Rating Scale (VRS), and Numerical Rating Scale (NRS), as well as methods using biochemical markers in blood and methods that visualize changes inside the muscle, such as ultrasound imaging and magnetic resonance imaging (MRI). Specifically, as shown in Figure 1, the VAS asks the subject to mark the degree of pain on a 10 cm line, with the left end being "no pain at all" and the right end being "the worst pain imaginable or the worst pain imaginable." The VRS evaluates pain by arranging words that represent pain intensity on a 3 to 5 scale in numerical order (e.g., no pain, a little pain, pain, severe pain, unbearable pain). The NRS asks the subject to rate pain on an 11-scale scale from 0 to 10, with 0 being no pain at all and 10 being the worst pain imaginable.

[0016] Subjects who take the "composition for suppressing muscle pain" of the present invention are not limited to athletes, sports enthusiasts, etc., but may also be subjects who need to prevent or improve muscle pain associated with exercise. In addition, the subjects may be mammals other than humans (horses (e.g., race horses), livestock such as cows, pets such as dogs and cats, ornamental animals kept in zoos, etc.).

[0017] The "composition for suppressing muscle pain" of the present invention is a composition that has the effect of suppressing exercise-induced muscle pain when an animal including a human (e.g., a mammal, hereinafter also referred to as a subject) ingests the composition for suppressing muscle pain of the present invention, compared to when the composition is not ingested.

[0018] The citrate salts contained in the composition of the present invention include potassium citrate, sodium citrate, or a mixture thereof. Since citric acid is a trivalent carboxylic acid, potassium citrate is also available in three types: monopotassium citrate, dipotassium citrate, and tripotassium citrate, and the same is true for other salts such as sodium citrate. The citrate salt may be a hydrate, and examples of the hydrate include potassium citrate monohydrate (C6H5K3O7·H2O) and sodium citrate dihydrate (C6H5Na3O7·2H2O). In the case of a mixture of potassium citrate and sodium citrate, there is no particular limitation on the content ratio as long as a muscle pain suppression effect is obtained, but for example, the content ratio of potassium citrate to sodium citrate in the composition (molar ratio in anhydrous terms) can be 1.00:0.50-1.50, preferably 1.00:0.80-1.20, more preferably 1.00:0.90-1.10, even more preferably 1.00:0.95-1.05, even more preferably 1.00:0.98-1.02, and most preferably 1.00:1.00. In addition, using the salt ratio as an indicator, the ratio of potassium citrate to sodium citrate in the composition can also be determined so that the molar ratio of potassium ions to sodium ions is 1.00:0.50 to 1.50, preferably 1.00:0.80 to 1.20, more preferably 1.00:0.90 to 1.10, even more preferably 1.00:0.95 to 1.05, even more preferably 1.00:0.98 to 1.02, and most preferably 1.00:1.00. In particular, when the content ratio of tripotassium citrate to trisodium citrate (molar ratio calculated on anhydrous basis) in the "composition for suppressing muscle pain" of the present invention is 1.00:0.90-1.10, preferably 1.00:0.95-1.05, more preferably 1.00:0.98-1.02, and most preferably 1.00:1.00, the "composition for suppressing muscle pain" of the present invention can exhibit an even more advantageous effect of not disrupting the mineral balance in the blood even when ingested by animals, including humans.

[0019] In addition to the citrate salt, the composition of the present invention may also contain citric acid, mainly for flavoring purposes. Examples of citric acid include anhydrous citric acid and citric acid monohydrate. When citric acid is further added in addition to the above citrate salt, there is no particular limitation on the content ratio as long as a good taste is imparted, but for example, the content ratio (molar ratio in anhydrous terms) of potassium citrate, sodium citrate, and citric acid in the composition can be 2.00:1.60-2.40:0.70-3.30, preferably 2.00:1.80-2.20:0.80-3.20, more preferably 2.00:1.90-2.10:0.90-3.10, even more preferably 2.00:1.96-2.04:2.90-3.10, and most preferably 2.00:2.00:3.00.

[0020] The content of the citrate salt, or a mixture of the citrate salt and citric acid in the composition of the present invention is not particularly limited as long as a muscle pain suppression effect is obtained, but is, for example, in the range of 0.01 to 50% by mass, preferably 0.01 to 31% by mass, relative to the mass of the total composition.

[0021] The composition of the present invention may contain sucrose, mainly for flavoring purposes. Examples of sucrose that can be used include granulated sugar, powdered sugar, white sugar, brown sugar, cane sugar, beet sugar, brown sugar, medium-sized coarse sugar, and white coarse sugar. When sucrose is added in addition to the citrate, the content is not particularly limited as long as a good taste is imparted, but for example, the content is preferably 0.01 to 90% by mass, more preferably 0.01 to 60% by mass, calculated as sucrose relative to the total mass of the composition. If the sucrose content is less than 0.01% by mass, the sweetening effect cannot be obtained, and if it exceeds 90% by mass, functional ingredients and other seasonings cannot be blended in sufficient amounts.

[0022] The composition of the present invention may contain additives other than the citric acid and sucrose.The additives may be any additive that does not inhibit the muscle pain suppression effect, and are not particularly limited. For example, carriers, excipients, lubricants, binders, disintegrants, diluents, stabilizers, isotonicity agents, pH adjusters, buffers, etc. may be used as additives for formulation.The additives may be the remainder of citrate, citric acid, sucrose, etc., and the content of the additives is not particularly limited as long as it does not affect the effects of the present invention.

[0023] The "composition for suppressing muscle pain" of the present invention can also be used to prepare food and drink products for suppressing muscle pain. In addition to the muscle pain suppressing composition, other food ingredients and / or food additive ingredients can be added to the "food and drink for suppressing muscle pain" of the present invention, so long as they have a muscle pain suppressing effect. For example, in order to impart palatability, sweeteners (sugars, liquid sugars, fructose, maltose, brown sugar, etc.), sugar alcohols (erythritol, etc.), high-intensity sweeteners (stevia, aspartame, sucralose, acesulfame potassium), acidulants, thickening polysaccharides, flavorings, fruit juice, vegetable juice, etc. can be added. In addition, in order to impart functionality, vitamins, functional materials, probiotic lactic acid bacteria, etc. can be added to form the "food and drink for suppressing muscle pain" of the present invention.

[0024] The form of the "food or drink for suppressing muscle pain" of the present invention is not particularly limited as long as it is in a form that can be orally ingested, such as a solution, suspension, emulsion, powder, or solid molded product. Specific examples of such beverages include beverages such as soft drinks, fruit juice drinks, vegetable drinks, soy milk drinks, coffee drinks, tea drinks, powdered drinks, concentrated drinks, and alcoholic drinks; powders used as raw materials for the beverages; confectioneries such as tablet candies, gummies, jellies, soft candies, hard candies, chocolates, cookies, biscuits, cakes, pies, snacks, crackers, Japanese sweets, and dessert sweets; dairy products such as milk drinks, yogurts, lactic acid bacteria drinks, ice creams, and creams; instant foods such as instant noodles, retort foods, canned foods, microwave foods, instant soups and miso soups, and freeze-dried foods; wheat flour products such as bread, pasta, noodles, cake mixes, and breadcrumbs; seasonings such as sauces, tomato processed seasonings, flavor seasonings, cooking mixes, sauces, dressings, soups, and curry and stew bases; processed oils and fats, butter, margarine, mayonnaise, and other oils and fats; agricultural processed products such as canned agricultural products, jams and marmalades, and cereals; and frozen foods. Beverages and confectioneries are preferred, and soft drinks, tablets, gummies, and jellies are more preferred.

[0025] Foods also include categories such as health foods, functional foods, nutritional supplements, foods with functional claims, foods for specified health uses, foods for the sick, powdered milk for pregnant women or nursing mothers, or foods labeled as being used to prevent or improve muscle pain.

[0026] Furthermore, the "food and drink for suppressing muscle pain" of the present invention can be in the form of a powder in a container, as one embodiment for the purpose of providing it on the market. The container can be a known one such as paper, a bag, a box, a can, or a bottle. The capacity of the container is not particularly limited, and is, for example, 1 to 5000 g, preferably 2 to 4000 g, and more preferably 3 to 3000 g. In particular, in the case of a family size, it is, for example, 300 to 5000 g, preferably 300 to 4000 g, and more preferably 300 to 3000 g, and in the case of a personal size, it is, for example, 1 to 500 g, preferably 2 to 250 g, and more preferably 3 to 200 g.

[0027] Furthermore, the "food and drink for suppressing muscle pain" of the present invention can be in the form of a containerized drink (a drink in which powder is dispersed and dissolved) as one embodiment for the purpose of providing it on the market. The container can be a known container such as a paper container, a soft bag, a plastic bottle, a can, or a bottle. The capacity of the container is not particularly limited, and is, for example, 1 to 5000 g, preferably 2 to 4000 g, and more preferably 3 to 3000 g. Among them, in the case of a family size, it is, for example, 300 to 5000 g, preferably 300 to 4000 g, and more preferably 300 to 3000 g, and in the case of a personal size, it is, for example, 10 to 500 g, preferably 20 to 500 g, and more preferably 30 to 500 g.

[0028] The "food and drink for suppressing muscle pain" of the present invention is in a unit package form per meal, and in the unit, the mass of the citrate or the mixture of the citrate and citric acid is preferably adjusted to 200 mg or more as a meal intake, specifically, 200 to 4000 mg, preferably 50 to 2000 mg, more preferably 400 to 1500 mg, and even more preferably 500 to 1000 mg. Here, "unit package form per meal" means a form in which the intake amount per meal is predetermined, for example, a food that can be orally ingested in a specific amount, not only a general food but also a beverage (such as a drink), a health supplement, a health functional food, a supplement, etc.

[0029] In the case of liquid beverages, gels, pastes, and jelly pastes, and solid foods in tablet, chewable, powder, granules, capsules, and blocks, the "unit package form per meal" may be a form in which a specific amount (dosage) can be specified by a packaging container such as a metal can, glass bottle (bottle, etc.), plastic container (PET bottle, etc.), pack, pouch, film container, or paper box, or a form in which a specific amount can be specified by displaying the intake amount (usage, dosage) per meal on the packaging container or on a website, etc. The "food and drink for suppressing muscle pain" of the present invention can be easily ingested and swallowed regardless of the form, such as a bite-sized block or a mini-canned drink that can be consumed in one gulp, and can be appropriately modified to a form that is easy to ingest and swallow and further improves convenience for children and the elderly.

[0030] The method of ingesting (administering) the "composition for suppressing muscle pain" or "food or beverage for suppressing muscle pain" of the present invention to a subject in need of preventing or improving muscle pain can be appropriately selected from oral ingestion, enteral administration, etc., depending on the subject and purpose, but oral ingestion is preferred.

[0031] The intake amount of the "composition for suppressing muscle pain" or "food or drink for suppressing muscle pain" of the present invention can be appropriately selected from a wide range depending on the subject's sex, age, physiological condition, formulation form, route of administration, number of administrations, concentration of active ingredients, etc., but for example, the mass of citrate, or a mixture of citrate and citric acid added to the "composition for suppressing muscle pain" or "food or drink for suppressing muscle pain" of the present invention per day for an adult may be about 1 to 20 g, preferably about 2 to 16 g, more preferably about 3 to 12 g, and even more preferably about 4 to 8 g. For example, the amount of citrate required for an adult per day to obtain a sufficient muscle pain suppression effect may be 1.5g, 3.1g, or 4.6g in the case of a mixture of potassium citrate and sodium citrate, and 9.4g, 7.8g, or 6.3g in the case of a mixture of citrate and citric acid, and the lower limit may be 1.8g, 2.3g, 3.6g, 4.5g, 5.4g, or 6.8g in the case of a mixture of citrate and citric acid, and the upper limit may be 13.7g, 11.4g, 11.0g, 9.2g, 9.1g, or 7.4g. The preferred range including the lower and upper limits of the daily amount may be appropriately adjusted depending on the type of citrate used and the mixing ratio with citric acid. Furthermore, administration may be, for example, once a day, or may be divided into multiple doses, such as 2, 3, 4, 5 or more times a day.

[0032] The "composition for suppressing muscle pain" of the present invention can be used as a feed additive or nutritional supplement for mammals other than humans to prevent or reduce muscle pain in mammals other than humans.

[0033] The shape of the feed additive or nutritional supplement for mammals other than humans is free, and can be, for example, in the form of granules or biscuits. In the case of granules, it is convenient to sprinkle it on staple feed for ingestion. In the case of sprinkling it on staple feed for ingestion, the shape may be made into a finer powder. In the case of biscuits, it is convenient to give it between meals. In this way, when it is given separately from the staple feed between meals, it may be formed into small pieces of other suitable sizes, for example, cubes or the like.

[0034] Therefore, the feed additive or nutritional supplement for non-human mammals of the present invention can be fed to non-human mammals by adding it to their staple feed or as a side dish, thereby allowing the non-human mammal to easily ingest the citrate salt, or a mixture of citrate salt and citric acid contained therein, in the amount required. Furthermore, non-human mammals that ingest this can prevent muscle pain and reduce the incidence of musculoskeletal diseases due to the action of the citrate salt, or a mixture of citrate salt and citric acid, contained in the feed additive or nutritional supplement for non-human mammals of the present invention. In this case, the feed additive for mammals other than humans is preferably given to the target animal at a daily dose of 0.1 to 5 g / kg body weight, preferably 0.1 to 3 g / kg body weight, and most preferably 0.1 to 2 g / kg body weight.

[0035] It is also known that racehorses have a high incidence of musculoskeletal diseases, and among these, muscle pain tends to account for a significantly high proportion. Therefore, the "muscle pain suppressing composition" of the present invention can be used as a racehorse feed additive or nutritional supplement for preventing or reducing muscle pain in racehorses. Racehorses that have ingested the racehorse feed additive or nutritional supplement of the present invention can prevent the above-mentioned muscle pain and reduce the incidence of musculoskeletal diseases due to the action of the citrate salt or a mixture of the citrate salt and citric acid, thereby maintaining their health and enabling them to maintain a longer lifespan as racehorses, and therefore the racehorse feed additive or nutritional supplement of the present invention is particularly useful.

[0036] The racehorse feed additive or nutritional supplement of the present invention can be given by adding it to a feed such as a complete mixed feed, for example, one day, preferably two days, more preferably three days, and most preferably four days before a race. In this case, the racehorse feed additive is preferably given to the target animal at a daily dose of 0.1 to 5 g / kg body weight, preferably 0.1 to 3 g / kg body weight, and most preferably 0.1 to 2 g / kg body weight. This can prevent or suppress the occurrence of muscle pain in the racehorse.

[0037] The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these examples. EXAMPLES

[0038] Example 1: Preparation of citrate beverage powder A citrate powder for beverages was prepared as follows. First, a citrate-citric acid composition containing potassium citrate monohydrate (C6H5K3O7·H2O), sodium citrate dihydrate (C6H5Na3O7·2H2O), and anhydrous citric acid (C6H8O7) was prepared with the composition shown in Table 1. Next, in order to give this citrate-citric acid composition a flavor suitable for drinking, anhydrous citric acid, powdered sugar (powdered sugar H (granulated sugar (sucrose) 98%, cornstarch 2%), Hiranoya Co., Ltd.), flavoring, and sucralose (Sunsweet SA-8020, San-Ei Gen F.F.I.) were added to prepare a citrate powder for beverages with the composition shown in Table 2. This was then divided into packets of 10g each. In the citrate beverage powder shown in Table 2, the content ratio (molar ratio in anhydrous terms) of potassium citrate, sodium citrate, and citric acid was approximately 2:2:3.

[0039] [Table 1]

[0040] [Table 2]

[0041] [Example 2] Effect of citrate drink on muscle pain The effect of citrate drink on muscle pain the day after playing sports was investigated in 98 adult men and women (73 men, 25 women (average age 24.3±13.5 years)) who are enthusiastic about various sports. The degree of muscle pain sensation was examined using the VAS (Visual Analog Scale) method. The participants were asked to write their impressions of the pain sensation of muscle pain compared to when they did not drink the drink on the scale shown in Figure 2. The citrate drink powder prepared in Example 1 was dissolved in about 300 mL of water per package (10 g), and the participants were asked to take up to two packages per day. The timing of taking the drink was before or during practice. Of the 98 subjects, responses were obtained from 62 judo enthusiasts (average age 20.3±5.1 years), 21 basketball enthusiasts (average age 15.0±5.1 years), and 11 golf enthusiasts (average age 55.2±5.8 years). In Figure 2, "-10 / strong" to "0 / unchanged" indicates the degree to which the citrate drinker felt more muscle pain, and "0 / unchanged" to "10 / weak" indicates the degree to which the citrate drinker felt less or less muscle pain. Also, the higher the VAS value, the higher the degree of pain felt.

[0042] The overall results are shown in Figure 3. As a result, the VAS was 2.4, which means that the degree of muscle pain felt was reduced by drinking the citrate drink, and it was clear that the occurrence of muscle pain was alleviated or prevented.

[0043] From the above results, it was found that the composition for suppressing muscle pain containing citrate has an effect of suppressing muscle pain (especially delayed onset muscle pain). In addition, the main ingredients of the composition of the present invention, citrate and citric acid, are approved as food additives, and it is found that the composition can be used continuously on a daily basis because of its excellent safety.

Claims

[Claim 1] A composition for suppressing muscle pain, comprising a citrate salt or a hydrate thereof.

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