Ophthalmic lens having extended depth of focus for improving intermediate vision

Abstract

To provide an ophthalmic lens having an extended depth of focus for improving intermediate vision.SOLUTION: Provided is an ophthalmic lens (such as an IOL) that is designed to enhance depth of focus for intermediate vision performance, while maintaining distance vision. The lens may include an optic having an anterior surface and a posterior surface disposed about an optical axis. Either one of the surfaces (e.g., the anterior surface) may have a surface profile involving a superposition of at least three structures or profiles, including a base structure, a phase shift structure having an inner region, an outer region and a transition region, and a zonal structure having an inner power zone and an outer transition zone.SELECTED DRAWING: Figure 1A

Description

[Technical field]

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS This application claims the benefit of priority to U.S. Provisional Patent Application No. 63 / 010,792, filed April 16, 2020, entitled “OPHTHALMIC LENSES HAVING AN EXTENDED DEPTH OF FOCUS FOR IMPROVING INTERMEDIATE VISION,” with Myoung-Taek Choi, Sangyeol Lee, Shinwook Lee, and William Lee as inventors, and which is hereby incorporated by reference in its entirety as if fully set forth herein.

[0002] The present disclosure relates generally to the field of ophthalmic lenses, and more specifically to lenses having an extended depth of focus for improved intermediate distance vision. [Background technology]

[0003] Ophthalmic lenses, such as intraocular lenses, are routinely implanted in patients' eyes during cataract surgery to replace the natural crystalline lens. The optical power of the natural crystalline lens can be altered under the influence of the ciliary muscle to provide accommodation for viewing objects at different distances from the eye. Many intraocular lenses offer improved distance performance, but may lack the provision of an extended depth of focus for intermediate distance vision. Summary of the Invention [Means for solving the problem]

[0004] The present disclosure is generally directed to ophthalmic lenses (such as IOLs) that provide extended depth of focus for intermediate distance vision performance while maintaining distance visual acuity.

[0005] According to the present disclosure, the lens includes an optical component having a front surface and a rear surface disposed about an optical axis, at least one of the front surface and the rear surface having a surface profile corresponding to a superposition of at least three profiles. The three profiles include a phase shift structure, a zone structure, and a base structure or curvature. The phase shift structure is characterized by an inner region, an outer region, and a transition region. The inner region extends radially from the optical axis to a first boundary. The transition region is disposed between the inner region and the outer region and extends radially from the first boundary to a second boundary, the transition region adapted such that the phase of radiation incident thereon varies linearly over at least a portion of the radial range between the first boundary and the second boundary to generate a phase shift between the first boundary and the second boundary. The second boundary is disposed at a radial distance farther from the optical axis than the first boundary. The outer region extends radially from the second boundary toward an outermost edge of the optical component. The zone structure includes an inner power zone having a first curvature and an outer transition zone having a second curvature. The inner power zone extends radially from the optical axis to a second boundary and the outer transition zone extends radially to a third boundary. The third boundary is disposed at a further radial distance from the optical axis than the second boundary. A base curvature extends radially from the third boundary to an outermost edge of the optic. [Brief description of the drawings]

[0006] [Figure 1A] FIG. 1A illustrates a top view of an exemplary embodiment of an ophthalmic lens according to the present disclosure. [Figure 1B] FIG. 1B illustrates a side view of an exemplary embodiment of an ophthalmic lens according to the present disclosure. [Diagram 2] FIG. 2 shows an exploded cross-sectional view of the layers and resulting sag of an exemplary optical component according to the present disclosure. [Figure 3A-3B] 3A and 3B are plots of surface sag versus radial distance from the optical axis for a phase-shifting structure and a zone structure of an exemplary optical component according to the present disclosure, respectively. [Figure 3C] FIG. 3C illustrates a plot of compound surface sag versus radial distance from the optical axis for an example optical component in accordance with the present disclosure. [Figure 4A] FIG. 4A illustrates a plot of the through-focus modulation transfer function (MTF) of a conventional monofocal IOL in accordance with the present disclosure. [Figure 4B-4C] 4B and 4C show plots of the through-focus MTF of an optical component having only phase-shifting structures and only zonal power structures, respectively, in accordance with the present disclosure. [Figure 4D] FIG. 4D illustrates a through-focus MTF plot of an exemplary optical component in accordance with the present disclosure. [Diagram 5] FIG. 5 is a graph of visual acuity (VA) versus defocus and illustrates depth of focus extension for an exemplary optical component in accordance with the present disclosure. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0007] Those skilled in the art will appreciate that the drawings described below are for illustration purposes only and are not intended to limit the scope of the present disclosure.

[0008] Intraocular lenses (IOLs) are the most common type of lenses used in cataract surgery. Monofocal IOLs are intraocular lenses that have a single focus for one distance, e.g., near, intermediate, or far distance. Because monofocal IOLs can only be set for one distance, and most patients and practitioners choose the far distance focus, patients may need to utilize additional glasses to correct vision in near and / or intermediate distance vision. In addition, as the human eye ages, the depth of focus decreases. Depth of focus (measured in diopters, D) is the total distance in front of and behind the focus that an image can be focused without reducing sharpness beyond a certain tolerance. Conventional monofocal IOLs have limited depth of focus extension.

[0009] The present disclosure is generally directed to ophthalmic lenses (such as monofocal IOLs) having a surface profile that maintains distance image quality while improving intermediate distance vision, and further extends depth of focus. Although the following disclosure is described in relation to IOLs, it should be understood that the features and elements of the present disclosure are not limited to a particular type of IOL, but may be applied to monofocal or multifocal IOLs. In addition, the present disclosure may also be applied to non-IOL ophthalmic lenses, such as contact lenses. Furthermore, as used herein, the term "intraocular lens" (and its abbreviation IOL) is used to describe a lens that is implanted inside the eye to replace the eye's natural crystalline lens or enhance vision regardless of whether the natural crystalline lens is removed.

[0010] 1A and 1B, an exemplary embodiment of an intraocular lens 100 according to the present disclosure is shown. FIG. 1A shows a top view of an anterior surface 130 of the lens 100, and FIG. 1B shows a side view showing the anterior surface 130 and the posterior surface 140 of the lens 100. The lens 100 may include a number of haptics 110 generally operable to position and stabilize the lens 100 within the capsular bag of a patient's eye. The lens 100 may further include an optic 120 having an anterior surface 130 and a posterior surface 140 disposed about an optical axis 105 of the lens. As shown in FIG. 1A and 1B, the optical axis 105 passes through the geometric center of the optic 120. One of the anterior surface 130 and the posterior surface 140 may include either an aspheric or spherical profile, while the other surface may include a multi-layered surface profile formed by the superposition of three profiles or structures. For purposes of illustration, in Figure 1A a multi-layer surface profile is shown on the front surface 130 of the optic 120. However, it should be understood that the multi-layer surface profile shown and described in connection with Figure 1A may alternatively be applied on the rear surface 140 of the optic 120, and that an aspheric or spherical profile may be applied to the front surface 130 of the optic 120.

[0011] Reference is now made to FIG. 1A in conjunction with FIG. 2. FIG. 2 shows an exploded cross-sectional view illustrating the individual layers or structures 150, 160, 170 that form the multi-layer surface profile of the front surface 130 of the optical component 120, as well as the composite or resulting sag 180 of the front surface 130 of the optical component 120. FIG. 1A shows an overhead (top) view of the composite multi-layer surface profile of the front surface 130 of the optical component 120, with the radial boundaries 122, 124, 126, 128 of FIG. 1A corresponding to the boundaries of the structures 150, 160, 170 of FIG. 2. It should be understood that in FIG. 2, the left and right sides of the optical axis 105 are mirror images of each other. Thus, the structures, boundaries, and designations shown on a given side of the optical axis 105 may be equally applied to the other side of the optical axis 105.

[0012] The multi-layer surface profile of the anterior surface 130 may include a superposition of at least three profiles or structures: a phase-shifting structure 150, an aspheric zone structure 160, and an aspheric base structure 170. The zone structure 160 may further include a superposition of an inner optical power zone 162 and an outer transition zone 164. As discussed above, each of these structures may be defined in relation to a number of radial boundaries 122, 124, 126, 128 formed with increasing radial distance from the optical axis 105 of the optic 120. The multi-layer surface profile (Z) of the anterior surface 130 of the optic 120 (including the phase-shifting structure 150, the zone structure 160, and the base structure 170) may include a phase-shifting structure 150, an aspheric zone structure 160, and an aspheric base structure 170. total ) may be defined by the following formula: Formula (1) Z total =Z aux +Z zone1 +Z zone2 +Z base , During the ceremony, Z aux represents the surface profile of the phase shift structure 150, Z zone1 represents the surface profile of the inner power zone 162 of the zone structure 160; Z zone2 represents the surface profile of the outer transition zone 164 of the zone structure 160; Z baserepresents the surface profile of the base structure 170. Each of these structures 150, 160, 170 will be described in turn.

[0013] First, the phase shift structure 150 may comprise a trapezoidal phase shift (TPS) feature having an inner region 152, a transition region 154, and an outer region 156. The inner region 152 may extend radially from the optical axis 150 to a first radial boundary 122. The transition region 154 may extend radially from the first radial boundary 122 to a second radial boundary 124 and is disposed at a greater radial distance from the optical axis 105 than the first radial boundary 122. The transition region 154 may be configured such that the phase of radiation incident thereon changes linearly over at least a portion of the radial range between the first radial boundary 122 and the second radial boundary 124 to produce a phase shift between the first radial boundary 122 and the second radial boundary 124. An outer region 156 of the phase-shifting structure 150 may extend radially from the second radial boundary 124 to the outermost edge 128 of the optical component 120 .

[0014] The trapezoidal phase shift structure 150 shown in FIG.

number

number

[0015] In one embodiment, the phase-shifting structure 150 defined by equations (2a) and (2b) is characterized by a substantially linear phase shift across the transition region 154. More specifically, the phase-shifting structure 150 provides a linearly increasing phase shift from an inner boundary of the transition region 154 (corresponding to the first radial boundary 122) to an outer boundary of the transition region 154 (corresponding to the second radial boundary 124), and an optical path difference between the inner and outer boundaries (or between the first radial boundary 122 and the second radial boundary 124) corresponds to a non-integer fraction of the design wavelength.

[0016] In operation, the trapezoidal phase shift structure 150 can generate a continuous focus shift due to the traveling wavefront delay between the inner region 152 and the outer region 156, which results in a collective depth of focus expansion. The phase shift structure generates a varying amount of phase shift in the light waves passing through the optical component 120 (depending on the region of the optical component 120 through which the light waves pass), and the constructive interference between the light waves with varying amounts of phase shift can generate an expanded depth of focus. As described below, additional depth of focus expansion can be achieved by adding an inner power zone 162 of the zone structure 160 to the phase shift structure 150. In this case, the phase shift structure 150 can help mitigate undesirable pupil-dependent focus shifts that may result from the enhanced depth of focus expansion caused by the inner power zone 162. In addition, without the trapezoidal phase shift structure 150, the optical component 120 would essentially function as a bifocal design.

[0017] In one embodiment, the radial distance r (from the optical axis 105 to the first radial boundary 122) of the inner region 152 of the phase shift structure 150 1The radial distance r from the optical axis 105 to the second radial boundary 124 may include values ​​ranging from about 0.45 mm to 0.75 mm. 2 may include values ​​ranging from about 0.75 mm to 1.05 mm. In addition, the step height Δ of the phase shift structure 150 may be about −2.1 μm.

[0018] 1A in conjunction with FIG. 2, the zone structure 160 may include an inner power zone 162 and an outer transition zone 164. The inner power zone 162 may have a first curvature and may extend radially from the optical axis 105 to the second radial boundary 124, and may overlap with the inner region 152 and the transition region 154 of the phase shift structure 150 as shown in FIG. 2. The inner power zone 162 may include a refractive surface and may be arranged to extend the depth of focus for improved intermediate vision performance. Specifically, the trapezoidal phase shift structure 150 may have the ability to improve the depth of focus and visual acuity for intermediate vision by itself, while the inner power zone 162 having a higher optical power than the base structure 170 may create an add power effect, and when combined with the phase shift structure 150, may further increase the depth of focus and improve intermediate vision. Furthermore, the combination of the trapezoidal phase shift structure 150 and the inner power zone 162 allows the optic to provide flexible mid-distance vision control in terms of both focal length and power. In one embodiment, the inner power zone 162 is located in the innermost region of the optic 120. This placement is particularly important for extending the depth of focus and improving vision. In one embodiment, the range of add power in the inner power zone 162 can be 0.7D to 2.4D. In one embodiment, the inner power zone 162 can extend the depth of focus to 2.38D and improve vision by 0.2 for pupil diameters of 2mm to 6mm.

[0019] In one embodiment, the inner power zone 162 shown in FIG. 2 is configured according to the following formula:

number

[0020] In one embodiment, r 2 may include values ​​ranging from about 0.45 mm to 0.80 mm. In one embodiment, r in equation (3) for the inner power zone 162 2 The value of r in equation (2a) for the trapezoidal phase shift structure 150 2 In yet another embodiment, the value of r in equation (3) for the inner power zone 162 may be substantially equivalent to 2 and the value of r in equation (2a) for the trapezoidal phase shift structure 150. 2 There may be some variance between the values ​​of . Thus, in some embodiments, the location of the second radial boundary 124 may be understood as a reference point that may vary or differ with respect to independent structures, such as the phase-shifting structure 150 and the zone structure 160 of the optic 120. The base curvature c of the inner power zone 162 may be calculated based on the .alpha.-to-.alpha. values. 1 For example, for a mid-distance refractive power of 21D, the diopter value is approximately 19.0 to 20.2 mm. -1 The conic constant k can range from 1 can range in value from approximately -100 to -30. The fourth-order aspheric coefficient A 4 ' is approximately -6.5 x 10 -4 ~-1.0×10 -4 mm -3 The sixth order aspheric coefficient A 6 ' is approximately -1.0 x 10 -5 ~3.0×10 -5 mm-5 In one embodiment, fourth and sixth order aspheric coefficients can be selected to optimize the spherical aberration of optical component 120.

[0021] The zone structure 160 may further include an outer transition zone 164 having a second curvature. As shown in the cross-sectional view of FIG. 2, the outer transition zone 164 may functionally extend radially from the second boundary 124 to the third boundary 126, with the third boundary 126 being located at a greater radial distance from the optical axis 105 than the second boundary 124. Although FIG. 2 shows the functional boundary of the outer transition zone 164 as extending radially from the second radial boundary 124 to the third radial boundary 126, it should be understood that the structure forming the outer transition zone 164 technically extends radially from the optical axis 105 to the third radial boundary 126. However, the innermost region 164a of the outer transition zone 164 (shown in dotted lines) from the optical axis 105 to the second radial boundary 124 does not functionally contribute to the multi-layered surface profile of the front surface 130 of the optical component 120. In other words, only the outermost region 164b of the outer transition zone 164 functionally contributes to the sag 180 as a result of the multi-layered surface profile of the anterior surface 130. The outer transition zone 164 may include a refractive surface and may function to provide a smooth transition from the inner power zone 162 to the base structure 170.

[0022] In some embodiments, the outer transition zone 164 may be omitted from the design of the optical component 120. In such embodiments, it should be understood that the remaining structures (e.g., the phase-shifting structure 150, the inner power zone 162, and / or the base structure 170) may be modified to provide a suitable transition from the inner power zone 162 to the base structure 170. For example, the base structure 170 (described below) may be modified to functionally begin at the second radial boundary 124 (instead of the third radial boundary 126) and may extend radially to the outermost edge 128 of the optical component. As a further example, the superposition of the outer portion 162b of the inner power zone 162 of the zone structure 160 with the transition zone 154 of the phase-shifting structure 150 may provide a transition from the inner power zone 162 to the base structure 170. It should be understood that these and other modifications to the optical component are considered to be within the scope of the present disclosure.

[0023] The outer transition zone 164 shown in FIG. 2 has the following formula:

number

[0024] In one embodiment, the radial distance r from the optical axis 105 to the second radial boundary 124 2can include values ​​ranging from about 0.45 mm to 0.80 mm. In one embodiment, r in equation (4) for the outer transition zone 162 2 The value of r in equation (2a) for the trapezoidal phase shift structure 150 2 In yet another embodiment, the value of r in equation (4) for the outer transition zone 162 may be substantially equivalent to 2 and the value of r in equation (2a) for the trapezoidal phase shift structure 150. 2 There may be some dispersion between the values ​​of the radial distance r from the optical axis 105 to the third radial boundary 126. 3 may include values ​​ranging from about 0.60 mm to 1.2 mm. 2 Approximately 20.0 to 20.5 mm -1 The conic constant k can range from 2 can range in value from approximately -100 to -30. The fourth-order aspheric coefficient A 4 '' is -6.5 x 10 -4 ~-1.0×10 -4 mm -3 The 6th order aspheric coefficient A 6 '' is approximately -1.0 x 10 -5 ~3.0×10 -5 mm -5 The range may include values.

[0025] With continued reference to FIG. 1A in conjunction with FIG. 2, the base structure 170 may include a third profile or structure of the multi-layer surface profile of the front surface 130 of the optical component 120. In some embodiments, the base structure 170 may be in the form of a base curvature. As shown in the cross-sectional view of FIG. 2, the base structure 170 may functionally extend radially from the third radial boundary 126 to the outermost edge 128 of the optical component. Although FIG. 2 shows the functional boundary of the base curvature or base structure 170 (i.e., extending radially from the third radial boundary 126 to the outermost edge 128 of the optical component), it should be understood that the base structure 170 technically extends radially from the optical axis 105 to the outermost edge 128 of the optical component 120. However, the innermost region 170a of the base structure 170 (shown in dotted lines from the optical axis 105 to the third radial boundary 126) does not functionally contribute to the multi-layer surface profile of the front surface 130 of the optical component 120. In other words, only the outermost region 170 b of the base structure 170 functionally contributes to the sag 180 resulting from the multi-layered surface profile of the front surface 130 .

[0026] In one embodiment, the base structure 170 may include an aspheric profile having a base lens power, as that term is understood in the art. In one embodiment, the base structure may have an optical power in the range of -15D to +50D.

[0027] The base structure 170 shown in FIG. 2 has the following formula:

number

[0028] In one embodiment, the radial distance r from the optical axis 105 to the third radial boundary 126 3 may include values ​​ranging from about 0.60 mm to 1.2 mm. The base curvature c of the base structure 170 may include values ​​ranging from about 0.0152 mm to 1.2 mm. -1 ~ approx. 0.0659mm -1 The conic constant k may include values ​​ranging from about -1162 to about -19. The fourth-order aspheric coefficient A 4 is approximately 0.0 mm -3 ~Approx.-5.3×10 -3 mm -3 The 6th order aspheric coefficient A 6 is approximately 0.0 mm -3 ~Approx. 1.53×10 -4 mm -5 The range may include values.

[0029] With further reference to Figure 2, as described above, the superposition of structures 150, 160, 170 may result in a composite multi-layer surface profile (labeled "resulting sag" 180 in Figure 2). The resulting sag 180 may further correspond to first, second, third, and fourth regions 182, 184, 186, 188 defined by radial boundaries 122, 124, 126, 128, respectively. Each of the first, second, third, and fourth regions 182, 184, 186, 188 of the resulting sag 180 may result from the composite contribution of one or more of the structures 150, 160, 170 described above.

[0030] For example, a first region 182 of the resultant sag 180 may be defined as a region extending radially from the optical axis 105 to the first radial boundary 122. In one embodiment, the first region 182 may be formed by the overlap of the inner region 152 of the phase-shifting structure 150 and the inner portion 162a of the inner optical power zone 162 of the zone structure 160. In one embodiment, the first region 182 may not include a contribution from the outer transition zone 164 (e.g., the innermost region 164a of the outer transition zone 164) or the base structure 170 (e.g., the innermost region 170a of the base structure) of the zone structure 160 because, as discussed above, the innermost region 164a of the outer transition zone 164 and the innermost region 170a of the base structure do not functionally contribute to the resultant sag 180 of the first region 182. In yet another embodiment, the first region 182 of the resultant sag 180 may be defined only by the inner power zone 162, and more specifically, only by the inner portion 162a of the inner power zone 162. In other words, the inner region 152 of the phase-shifting structure may not functionally contribute to the resultant sag. The first region 182 may include a first compound aspheric profile.

[0031] A second region 184 of the resulting sag 180 may be defined as a region extending radially from the first radial boundary 122 to the second radial boundary 124. In one embodiment, the second region 184 may be formed by the overlap of the transition region 154 of the phase-shifting structure 150 and the outer portion 162b of the inner optical power zone 162 of the zone structure 160. In one embodiment, the second region 184 may not include a contribution from the outer transition zone 164 (e.g., the innermost region 164a of the outer transition zone 164) or the base structure 170 (e.g., the innermost region 170a of the base structure) of the zone structure 160, because the innermost region 164a of the outer transition zone 164 and the innermost region 170a of the base structure 170 do not functionally contribute to the resulting sag 180 of the second region 184. The transition region 154 (having a single step phase shift), when combined with the outer portion 162b of the inner power zone 162, can enable the resulting second region 184 to act as a transition from the first region 182 to the third region 186. The second region 184 can include a second compound aspheric profile.

[0032] 2, a third region 186 of the resultant sag 180 may be defined as a region extending radially from the second radial boundary 124 to the third radial boundary 126. In one embodiment, the third region 186 may be formed by the overlap of the outermost region 164b of the outer transition zone 164 of the zone structure 160 with the outer region 156 of the phase shift structure 150. The third region 186, which is a combination of the outermost region 164b of the outer transition zone 164 and the outer region 156, may function as a transition from the second region 184 to the fourth region 188. In one embodiment, the third region 186 may not include a contribution from the base structure 170 (e.g., the innermost region 170a of the base structure) because the innermost region 170a of the base structure does not functionally contribute to the resultant sag 180 of the third region 186. In yet another embodiment, the third region 186 may be defined only by the outer transition zone 164 of the zone structure 160, more specifically, the outermost region 164b of the outer transition zone 164. In other words, the outer region 156 of the phase shift structure may not functionally contribute to the resulting sag. The third region 186 may include a third compound aspheric profile.

[0033] A fourth region 188 of the resultant sag 180 may be defined as a region extending radially from the third radial boundary 126 to the outermost edge 128 of the optic. In one embodiment, the fourth region 188 may be formed by the superposition of the outer region 156 of the phase-shifting structure 150 and the base structure 170. In yet another embodiment, the fourth region 188 may be defined solely by the base structure 170. In other words, the outer region 156 of the phase-shifting structure 150 may not functionally contribute to the resultant sag. The fourth region 188 may include a fourth compound aspheric profile.

[0034] 1A and 2 and defined by equations (1)-(5) is a combination of a trapezoidal phase shifting structure and a zonal refractive surface with an add power effect, which together can improve intermediate vision performance and extend depth of focus while maintaining distance vision. It should be understood that various modifications, enhancements, and adjustments can be made to the optical component 120 described herein without departing from the spirit and scope of the present disclosure.

[0035] Reference is now made to Figures 3A-3C, which show the surface profile of the front surface 130 of the optical component 120, as defined by equations (1)-(5) shown in Figures 1A and 2, and graphed as plots 310, 320, and 330 of sag versus radial distance from the optical axis 105 of the optical component 120. Specifically, Figure 3A shows a sag plot 310 of the trapezoidal phase shift structure (element 150 in Figure 2) of the optical component 120. Figure 3B shows a unitless sag plot 320 of the zone structure (element 160 in Figure 2) of the optical component 120. Figure 3C shows a sag plot 330 of the composite multi-layer surface profile of the front surface 130 of the optical component 120. In all three plots of Figures 3A-3C, the radius is zero at the optical axis 305. As shown in Figure 3C, the sag curve is substantially parabolic, consistent with an aspheric lens surface. It should be understood that Figures 3A-3C are shown for illustrative purposes only, i.e., to represent the shapes of the curves, and therefore may not be to scale and may not represent the positions of the curves as a function of particular data points and / or units of measurement.

[0036] Reference is now made to Figures 4A-4D, which show through-focus modulation transfer function (MTF) plots 410, 420, 430, 440 for four optics. Figure 4A shows an MTF plot 410 for a monofocal IOL optic. Figure 4B shows an MTF plot 420 for an optic with a trapezoidal phase shift (TPS) structure (without a zonal add power structure). Figure 4C shows an MTF plot 430 for an optic with a zonal add power structure (without a phase shift structure). Figure 4D shows an MTF plot 440 for an example of an optic 120 based on the design shown in Figures 1A and 2 and defined by equations (1)-(5). These plots 410, 420, 430, 440 can be comparatively analyzed to further understand the improvements provided by the exemplary optical design of the present disclosure (shown in plot 440). For example, as shown in Figure 4A, the monofocal IOL optic lacks an extended depth of focus. Secondly, as shown in FIG. 4B, the optics with trapezoidal phase shift structure (without zonal power addition structure) have limited depth of focus range and poor MTF at defocus beyond 0.5D (near-sighted) range. Thirdly, as shown in FIG. 4C, the optics with zonal power addition structure (without phase shift structure) exhibit bifocality as evidenced by two distinct peaks at positive and negative focus shifts. This strong bifocality may cause undesirable pupil-dependent focus shift and / or halo. Finally, as shown in FIG. 4D, the exemplary optics based on the design shown in FIG. 1A and FIG. 2 and defined by the formulas (1)-(5) of the present disclosure provide extended intermediate vision without sacrificing distance vision and with less visual impairment than that of a monofocal IOL. As further shown in FIG. 4D, the exemplary optics further provide enhanced depth of focus extension and MTF performance, for example, especially at intermediate vision of 1.0D to about 1.5D.

[0037] Reference is now made to FIG. 5, which illustrates a simulated monocular visual acuity (VA) plot 500 for an optic based on the design shown in FIG. 1A and FIG. 2 and defined by Equations (1)-(5), for example. Visual acuity (VA) is a primary measure of visual function in both clinical practice and research. VA can be modeled using the intersection of the ocular modulation transfer function (MTF) and the retinal threshold function. In FIG. 5, the solid black curve 510 represents a monofocal IOL, and the multiple dotted curves 520, 530, 540, 550, 560 represent example optics according to the present disclosure. As shown in the graph, each of the example optics is associated with a different add power extension. As shown in FIG. 5, each of the curves for the example optics 520, 530, 540, 550, 560 illustrates the depth of focus extension for the monofocal IOL 510. The depth of focus extension ranges from 0.42D in exemplary optic 520 to a maximum extended depth of focus reaching 1.38D (shown as 570) in exemplary optic 560. It should be understood that there is some tradeoff in visual acuity as the depth of focus is extended, but an optimal design may attempt to balance these considerations.

[0038] In use, the intraocular lenses described herein are adapted to be inserted into a human eye using conventional surgical techniques modified in accordance with the present teachings. Typically, the natural lens is first removed, and the IOL can be folded to a compact size for insertion through an incision or opening in the capsular bag. After insertion, the IOL can be manipulated to position it appropriately within the capsular bag.

[0039] A variety of techniques and materials can be used to manufacture the lenses described in this disclosure. For example, the optic 120 of FIGS. 1A and 1B can be formed from a variety of biocompatible polymeric materials. Some suitable biocompatible materials include, but are not limited to, soft acrylic polymers, hydrogels, polymethylmethacrylate, polysulfone, polystyrene, cellulose, acetate butyrate, or other biocompatible materials. By way of example, in one embodiment, the optic 120 can be formed from a soft acrylic polymer commonly known as Acrysof® (a cross-linked copolymer of 2-phenylethyl acrylate and 2-phenylethyl methacrylate). The haptics 110 of the lens can be formed from a suitable biocompatible material as described above. In some cases, the optic 120 and haptics 110 of the IOL can be manufactured as an integral unit, while in other cases, they can be formed separately and bonded together using techniques known in the art.

[0040] As used herein, "or" is inclusive and not exclusive, unless expressly indicated otherwise or the context indicates otherwise. Thus, as used herein, "A or B" means "A, B, or both," unless expressly indicated otherwise or the context indicates otherwise. Furthermore, "and" means both jointly and severally, unless expressly indicated otherwise or the context indicates otherwise. Thus, as used herein, "A and B" means "A and B, jointly or severally," unless expressly indicated otherwise or the context indicates otherwise.

[0041] It will be appreciated that the above-disclosed and other features and functions, or various alternatives thereof, may be desirably combined into many other different systems or applications. It is also understood that various presently unforeseen or unanticipated alternatives, modifications, variations, or improvements thereto may subsequently be made by those skilled in the art, and that such alternatives, modifications, and improvements are also intended to be included within the scope of the following claims. Those skilled in the art will appreciate that various modifications can be made to the above-described embodiments without departing from the scope of the present invention.

Claims

1. An ophthalmic lens, comprising: An optical component having a front surface and a rear surface disposed about an optical axis, at least one of the front surface and the rear surface having a composite multi-layer surface profile corresponding to a superposition of at least three profiles including a phase-shifting structure, a zone structure, and a base structure; the phase-shifting structure is characterized by an inner region, an outer region, and a transition region; the inner region extends radially a first radial distance from the optical axis to a first boundary; the transition region is disposed between the inner region and the outer region and extends radially from the first boundary to a second boundary, the transition region is adapted such that a phase of radiation incident on the transition region varies linearly over at least a portion of a radial range between the first boundary and the second boundary to produce a phase shift between the first boundary and the second boundary, the second boundary being disposed at a radial distance farther from the optical axis than the first boundary; the outer region extends radially from the second boundary toward an outermost edge of the optical component; the zone structure having an inner power zone having a first curvature and an outer transition zone having a second curvature, the inner power zone extending radially from the optical axis to the second boundary, the outer transition zone extending radially from the optical axis to a third boundary, the third boundary being disposed at a greater radial distance from the optical axis than the second boundary, the first curvature and the second curvature being non-zero curvatures, the first curvature being different from the second curvature; the base structure has a base curvature extending radially from the optical axis to the outermost edge of the optical component. An ophthalmic lens comprising an optical component.

2. The at least one surface profile of the front and rear surfaces has the following formula: Z ｔｏｔａｌ =Z ａｕｘ +Z ｚｏｎｅ１ +Z ｚｏｎｅ２ +Z ｂａｓｅ 10. The ophthalmic lens of claim 1 , wherein:

3. Z ａｕｘ corresponds to the phase shift structure, and the following formula: [0010] wherein: r denotes the radial distance of the optical component from the optical axis; r １ denotes the radial distance from the optical axis to the first boundary, r ２ denotes the radial distance from the optical axis to the second boundary, and, Δ is the following relationship: [0025] wherein: n １ denotes the refractive index of the material forming the optical component, n ２ denotes the refractive index of the medium surrounding the optical component, λ denotes the design wavelength, The ophthalmic lens of claim 2 , wherein α represents a non-integer fraction.

4. r １ 4. The ophthalmic lens of claim 3, wherein comprises a value in the range of 0.45 mm to 0.75 mm.

5. r ２ The ophthalmic lens of claim 3, wherein comprises a value in the range of 0.75 mm to 1.05 mm.

6. Z ｚｏｎｅ１ corresponds to the inner power zone and has the following formula: [0030] wherein: r denotes the radial distance of the optical component from the optical axis; c １ indicates the first curvature of the inner power zone; k １ represents the conic constant, r ２ denotes the radial distance from the optical axis to the second boundary, A ４ ' is the fourth-order aspheric coefficient, A ６ 3. An ophthalmic lens according to claim 2, wherein ' is a sixth order aspheric coefficient.

7. r ２ The ophthalmic lens of claim 6, wherein comprises a value in the range of 0.45 mm to 0.80 mm.

8. Z ｚｏｎｅ２ corresponds to the outer transition zone, and the following formula: [0045] wherein: r denotes the radial distance of the optical component from the optical axis; c ２ represents the second curvature of the outer transition zone. k ２ represents the conic constant, r ２ denotes the radial distance from the optical axis to the second boundary, r ３ indicates the radial distance from the optical axis to the third boundary, A ４ '' are the fourth-order aspheric coefficients, A ６ 3. The ophthalmic lens of claim 2, wherein .alpha.'' is a sixth order aspheric coefficient.

9. r ２ The ophthalmic lens of claim 8, wherein comprises a value in the range of 0.45 mm to 0.80 mm.

10. r ３ 9. The ophthalmic lens of claim 8, wherein comprises a value in the range of 0.60 mm to 1.20 mm.

11. Z ｂａｓｅ corresponds to the base curvature, and the following formula: [0050] wherein: r denotes the radial distance of the optical component from the optical axis; c indicates the value of the base curvature, k represents the conic constant, r ３ indicates the radial distance from the optical axis to the third boundary, A ４ are the fourth-order aspheric coefficients, A ６ 3. The ophthalmic lens of claim 2, wherein: is a sixth order aspheric coefficient.

12. r ３ The ophthalmic lens of claim 11, wherein comprises a value in the range of 0.60 mm to 1.20 mm.

13. a first region of the optical component including a first compound aspheric profile, the first region being defined from the optical axis and extending radially to the first boundary; a second region of the optic includes a second compound aspheric profile, the second region being defined from the first boundary and extending radially to the second boundary; a third region of the optic includes a third compound aspheric profile, the third region being defined from the second boundary and extending radially to the third boundary; The ophthalmic lens of claim 1 , wherein a fourth region of the optic comprises a fourth compound aspheric profile, the fourth region being defined from the third boundary to the outermost edge of the optic.

14. The ophthalmic lens of claim 1 , wherein the inner power zone is positioned to provide extended depth of focus for intermediate distance vision performance.

15. 15. The ophthalmic lens of claim 14, wherein the phase-shifting structure is positioned to mitigate pupil-dependent focus shift effects caused by the extended depth of focus by the inner power zone.

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