Cosmetic comprising high content of fulvic acid

Abstract

To provide a cosmetic that maintains stability despite a high content of a fulvic acid.SOLUTION: A fulvic acid is combined with a specific preservative and further with a pH adjuster. This can provide a stable cosmetic with a high content of the fulvic acid.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a cosmetic containing fulvic acid in a high content. The present invention also relates to a method for producing a cosmetic containing fulvic acid in a high content.

Background Art

[0002] Conventionally, fulvic acid has been known as a substance expected to have beauty and health effects because it contains abundant minerals, amino acids, etc. and can effectively transport them by chelation. For example, Patent Document 1 describes a composition for pre-treatment for hair removal or hair growth promotion containing fulvic acid as an active ingredient, and Patent Document 2 describes a cosmetic composition for preventing photoaging of the skin containing a humic extract containing fulvic acid.

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Patent Document 2

Summary of the Invention

Problems to be Solved by the Invention

[0004] Fulvic acid changes into a form that is easily transported to the stratum corneum of the skin by chelation. However, when mixed with a cosmetic base material, modulation occurs due to chelation or the like, and there has been a problem that it is difficult to manufacture as a cosmetic.

[0005] Generally, the shelf life of a cosmetic is set at 3 years unopened. In order to stabilize it as a cosmetic, it is necessary to add some kind of preservative or buffer. However, even when only 0.01% of a fulvic acid stock solution (usually a humic extract containing fulvic acid at a few% level) is blended with other cosmetic base materials, chelation occurs, making it difficult to stabilize it as a cosmetic.

[0006] Accordingly, an object of the present invention is to provide a stable cosmetic while highly formulating fulvic acid containing minerals and the like rich as a beauty component.

[0007] Furthermore, a further object of the present invention is to provide a method for producing a cosmetic having high stability while containing fulvic acid in a high content.

[0008] Other objects of the present invention will become apparent from the following description.

Means for Solving the Problems

[0009] In the present invention, it has been found that by combining fulvic acid, which causes chelation even in trace amounts as described above, with a specific preservative and further a pH adjuster, a cosmetic containing fulvic acid in a high content and having stability can be obtained.

[0010] That is, in the present invention, a cosmetic containing fulvic acid (for example, formulated in the form of a humic extract containing fulvic acid) in a high content can be obtained, such a cosmetic is stabilized without chelation, and further, in such a cosmetic, modulation such as insufficient dissolution or turbidity does not occur.

[0011] The present invention includes the following aspects. 1. A cosmetic containing at least 1% by weight of fulvic acid based on the total weight of the cosmetic. 2. The cosmetic according to 1 above, having a pH of 4.0 to 6.5. 3. The cosmetic according to 1 or 2 above, further containing pentylene glycol. 4. The cosmetic according to any one of 1 to 3 above, further containing a pH adjuster. 5. The cosmetic according to 4 above, wherein the pH adjuster is citric acid or a salt acceptable in the cosmetic. 6. The cosmetic according to any one of 1 to 5 above, wherein the fulvic acid is derived from a humic extract. 7. The cosmetic according to any one of 1 to 6 above, in a liquid form. 8. A cosmetic selected from the group consisting of beauty essence, moisturizing lotion, softening lotion, astringent lotion, skin care cosmetics, farming cosmetics, body cosmetics, base cosmetics, foundation, primer cream, face powder, and makeup cosmetics, the cosmetic according to any one of the above 1 to 7. 9. A method for manufacturing a cosmetic, comprising the following steps: a) adding fulvic acid to water and mixing; b) adding a preservative to the mixture obtained in step a) and mixing; c) adding a pH adjuster to the mixture obtained in step b) and mixing to adjust the pH of the mixture to 4.0 to 6.5 to obtain a cosmetic. The manufacturing method comprising the above steps. 10. The manufacturing method according to the above 9, wherein the preservative is pentylene glycol and the pH adjuster is citric acid or a salt acceptable in the cosmetic. 11. The manufacturing method according to the above 9 or 10, wherein the cosmetic contains at least 1% by weight of fulvic acid based on the total weight of the cosmetic. 12. The manufacturing method according to any one of the above 9 to 11, wherein the fulvic acid is added in the form of a humic extract containing fulvic acid.

Mode for Carrying Out the Invention

[0012] In one embodiment of the present invention, the present invention relates to a cosmetic (cosmetics) containing fulvic acid at a high concentration.

[0013] "Fulvic acid" is a substance contained in humus. In soil, lake bottoms, and sea bottoms, plant remains, animal excreta and remains are deposited, and these are generally called "soil organic matter", but the part excluding the remains of animals and plants is usually called "humus". Among humus, typically dark-colored (yellow, brown or black) macromolecular substances generated through decomposition and polycondensation by the action of microorganisms over thousands of years are "humic substances". "Fulvic acid" is a substance that can be separated and purified (for example, extracted) from humus (or humic substances), and is an organic acid soluble in acidic and basic aqueous solutions.

[0014] The fulvic acid used in the present invention is not particularly limited. For example, the fulvic acid extracted from humus (humic substances) with a solvent can be used as it is in liquid form (also referred to as "humic extract"), or after concentration or dilution, or it can be used in the form of a powder obtained by powdering the extract (for example, by drying). Therefore, in one embodiment of the present invention, the fulvic acid is derived from a humic extract. In this embodiment, the fulvic acid is added to the cosmetic in the form of a humic extract, and preferably, the fulvic acid extracted from humic substances with a solvent is used as it is, that is, as the undiluted humic extract.

[0015] Also, as described above, the fulvic acid used in the present invention is not particularly limited, and its origin and production area (the origin and production area of the humic extract) are not particularly limited either. For example, it can be obtained from humic shale, which is an ancient plant deposit (shale layer) in Emery County, Utah, USA.

[0016] The method for preparing a humic extract, that is, the method for extracting fulvic acid from humus (or humic substances) is not particularly limited, and known methods can be used. Examples of extraction means include solid-liquid extraction, liquid-liquid extraction, immersion, leaching, decoction, reflux extraction, supercritical fluid extraction, microwave extraction, mixing and stirring, or a combination of two or more of these.

[0017] For example, fulvic acid can be extracted by mixing humus with an extraction solvent. In that case, as the extraction solvent, for example, water (such as distilled water, ion-exchanged water, reverse osmosis water (RO water), etc.), alcohol (such as methanol, ethanol, propanol, etc.), mixtures thereof, etc. may be used. Preferably, water, particularly RO water, and more preferably neutral RO water, is used as the extraction solvent. Regarding the extraction, the amount of the extraction solvent relative to the humus, the extraction time, the extraction temperature, the pH of the extraction solvent, etc. can be appropriately set by those skilled in the art in consideration of the extraction efficiency, etc. For example, the humus can be mixed at a ratio of 5 to 35 parts by weight, preferably 15 to 25 parts by weight, per 100 parts by weight of the extraction solvent. The mixture is left, for example, at room temperature, usually for 24 to 96 hours, preferably for 48 to 72 hours, and the supernatant or filtrate of the mixture can be used as the humus extract. For this purpose, means such as decantation and filtration known to those skilled in the art can be used. Incidentally, the humus extract may be further subjected to a microbial removal treatment (for example, 0.22 μm filter treatment).

[0018] Incidentally, the humus extract can, if necessary, be further subjected to additional isolation or purification treatment of fulvic acid, such as concentration, vacuum concentration, distillation, fractional distillation, phase transfer, solvent extraction, crystallization, recrystallization, chromatography (or a combination of two or more of these).

[0019] The pH of the humus extract can be pH 1 to 6, preferably pH 1.5 to 5, more preferably pH 2 to 4, and even more preferably pH 2.7 ± 0.5, for example, pH 2.7 ± 0.3. The pH of the humus extract may be adjusted as appropriate using a pH adjuster. The pH adjuster for adjusting the pH of the humus extract is not particularly limited as long as it is a commonly used pH adjuster.

[0020] The average molecular weight of the fulvic acid in the humus extract can be less than 4,000, preferably 3,500 or less, more preferably 3,000 or less, and particularly preferably 1,000 to 3,000.

[0021] In one embodiment of the present invention, the fulvic acid is derived from a humic extract obtained by putting humus into water, immersing it, and then removing solids from the immersion mixture. That is, the fulvic acid is added to the cosmetic in the form of a fulvic acid-containing humic extract thus obtained.

[0022] More specifically, the humic extract can be produced, for example, as follows: Humus, such as humic shale mined from a mine in Emery County (Emery City), Utah, USA, is introduced into a storage tank containing, for example, water at room temperature (e.g., about 25 °C) (e.g., neutral RO water) in an amount sufficient to immerse the humic shale. Next, a water extraction treatment of the humic shale is performed. This treatment involves immersing the humic shale in the storage tank at, for example, room temperature, preferably for 24 to 96 hours, more preferably for 48 to 72 hours. When the concentration of fulvic acid reaches a desired value (e.g., about 4% by weight), solids (residue) are removed from the storage tank, for example, by filtration or decantation, and the water extract (dissolved water) of the humic shale is recovered in another tank. Then, if necessary, it is passed through a filter (e.g., a 0.22 μm filter) for the purpose of removing microorganisms, and appropriately, pasteurization is performed at a low temperature for 5 to 10 hours, for example, about 8 hours (including 0.5 to 3 hours, for example, 1 hour at 68 ± 2 °C at the center), filled into another container at 60 ± 5 °C, and naturally cooled to room temperature. The humic extract thus obtained preferably has a pH of 2.7 ± 0.2 and contains 4.0 ± 0.2% by weight of fulvic acid. Also, the humic extract preferably shows negative results in standard microbiological tests (total number of common bacteria, coliform group, Escherichia coli, Staphylococcus aureus, Salmonella, O157, Vibrio parahaemolyticus, Bacillus cereus, Clostridium welchii, mold count), and the contents of harmful substances such as arsenic (As 2 O 3 ), lead, tin, mercury, etc. are also below the detection limit.

[0023] As the fulvic acid used in the present invention, for example, various commercially available products can be used as they are, or can be appropriately concentrated or diluted. For example, the humic precursor aqueous solution "Lead Up" sold by T&G Co., Ltd., "Chelate Balance" sold by Miyamoto Japan Co., Ltd., "Dense Generation Fulvic Acid Product" (fulvic acid plant activator "God of Green") sold by Japan Fulvic Acid Comprehensive Research Institute Co., Ltd., "Humicle (registered trademark) EC Fulvic Acid" sold by Style and Value Japan Co., Ltd., "Fulvic Acid (stock solution)" of Japan Organic Mineral Co., Ltd., etc. can be mentioned. Also, standard substances distributed by the Japanese Humic Substances Society (for example, fulvic acid "Dando (brown forest soil)" derived from the Tando forest soil in Aichi Prefecture) can be used.

[0024] The cosmetic can contain fulvic acid in an amount of at least 1% by weight, for example, at least 1.2% by weight, at least 1.4% by weight, at least 1.6% by weight, at least 1.8% by weight, at least 2.0% by weight, at least 2.2% by weight, at least 2.4% by weight, at least 2.6% by weight, at least 2.8% by weight, at least 3.0% by weight, at least 3.2% by weight, at least 3.4% by weight, at least 3.6% by weight, at least 3.8% by weight, at least 4.0% by weight, at least 4.5% by weight, at least 5.0% by weight, at least 6.0% by weight, at least 7.0% by weight, at least 8.0% by weight, at least 9.0% by weight, or at least 10% by weight, based on the total weight of the cosmetic. Also, although there is no need to set a particularly clear value for the upper limit of the fulvic acid contained in the cosmetic, for example, it can be 40% by weight or less, for example, 30% by weight or less, 20% by weight or less, or 15% by weight or less, based on the total weight of the cosmetic.

[0025] Also, when the humic extract as described above is used as the fulvic acid, the cosmetic can contain the humic extract (for example, the undiluted solution of the humic extract) at, for example, at least 1% by weight, at least 5% by weight, at least 10% by weight, at least 15% by weight, at least 20% by weight, at least 25% by weight, at least 30% by weight, at least 35% by weight, at least 40% by weight, at least 45% by weight, at least 50% by weight, at least 55% by weight, at least 60% by weight, at least 65% by weight, at least 70% by weight, at least 75% by weight, at least 80% by weight, at least 85% by weight, at least 90% by weight, at least 95% by weight, at least 98% by weight based on the total weight of the cosmetic. Here, the above-mentioned humic extract can preferably contain 1 to 10% by weight, for example, 2 to 8% by weight, 3 to 6% by weight of fulvic acid based on the total weight of the humic extract. Particularly preferably, the fulvic acid content in the humic extract is 4 ± 1% by weight, for example, 4 ± 0.5% by weight or 4 ± 0.2% by weight based on the total weight of the humic extract.

[0026] The fulvic acid content (fulvic acid concentration) can be measured using a Baumé hydrometer, or can also be determined by a three-dimensional fluorescence method using the above-mentioned reference material published by the Japanese Humic Substances Society (for example, fulvic acid "Dando (brown forest soil)" derived from the Tando forest soil in Aichi Prefecture) as a reference material.

[0027] For cosmetics, it is obligatory to list all ingredients according to the Pharmaceutical Affairs Law. The ingredients of cosmetics are listed in descending order of the amount of formulation, and the ingredients of 1% or less are listed in any order. Therefore, generally, the ingredients formulated at 1% or more are judged to be in a large amount of formulation. Accordingly, the fulvic acid content (formulation amount) of at least 1% by weight in the cosmetics of the present invention is a high formulation.

[0028] Examples of the form of the cosmetic of the present invention include powders, liquids, solids, etc. Examples of the main dosage forms include aqueous systems, O / W emulsion systems, W / O emulsion systems, oily systems, and powder systems. In particular, an aqueous system is preferred. Examples of the cosmetic of the present invention include skin care cosmetics such as skin lotions, for example, daytime skin lotions or introductory skin lotions, moisturizing lotions, softening lotions, astringent lotions, etc.; farming cosmetics, body cosmetics; and base cosmetics (lotions, emulsions, creams), foundations, base creams, face powders, and makeup cosmetics.

[0029] In a preferred embodiment of the present invention, the cosmetic contains a preservative. Preferably, the preservative is L-ascorbic acid and / or pentylene glycol, more preferably pentylene glycol. In the present invention, it has been found that by using L-ascorbic acid and / or pentylene glycol as a preservative in a cosmetic, a stable cosmetic can be obtained even when the cosmetic contains a high concentration of fulvic acid. Furthermore, it has also been found that when pentylene glycol is used, a cosmetic showing extremely high stability can be obtained even after the addition of a pH adjuster.

[0030] The cosmetic can contain a preservative in an amount customary for preservatives contained in cosmetics. For example, the cosmetic can contain at least 0.01% by weight, at least 0.05% by weight, at least 0.1% by weight, at least 0.2% by weight, at least 0.3% by weight, at least 0.5% by weight, at least 1.0% by weight, at least 1.5% by weight, at least 2.0% by weight, at least 3.0% by weight, at least 5.0% by weight, at least 10% by weight, at least 15% by weight or at least 20% by weight of the preservative based on the total weight of the cosmetic. Also, the amount of the preservative can be, for example, 30% by weight or less, 20% by weight or less, 15% by weight or less, 10% by weight or less, 5.0% by weight or less, 4.0% by weight or less, 3.0% by weight or less, 2.0% by weight or less, 1.0% by weight or less, 0.5% by weight or less based on the total weight of the cosmetic. For example, the cosmetic can contain 0.01 - 20% by weight, 0.1 - 10% by weight, 0.2 - 5.0% by weight, 0.5 - 3.0% by weight or 1.0 - 2.5% by weight, for example, 0.1 - 0.5% by weight, 0.1 - 1.0% by weight or 0.1 - 2.0% by weight of the preservative, preferably L-ascorbic acid and / or pentylene glycol, more preferably pentylene glycol.

[0031] In a preferred embodiment of the present invention, the cosmetic contains a pH adjuster (also referred to as a "buffer"). Examples of the pH adjuster include acids such as hydrochloric acid, nitric acid, sulfuric acid, lactic acid, acetic acid, citric acid, and salts of these acids that are acceptable in cosmetics, preferably alkali metal salts, alkaline earth metal salts, ammonium salts, and the like. Here, the "salt acceptable in cosmetics" means a salt of the compound that does not induce serious irritation to the organism (typically a human) to which the compound is applied and does not impair the biological activity and physical properties of the compound. The pH adjuster may also be a base such as sodium hydroxide, potassium hydroxide, sodium carbonate, triethylamine, trimethylamine, ammonia, and the like. These pH adjusters can be used alone or, if necessary, in combination of two or more. Preferably, the pH adjuster is citric acid or a salt acceptable in cosmetics, such as an alkali metal salt, and more preferably, the pH adjuster is sodium citrate.

[0032] In one embodiment of the present invention, the pH of the cosmetic is adjusted to a pH of 4.0 to 6.5, preferably 4.5 to 6.0, by adding the pH adjuster. That is, the pH adjuster is contained in the cosmetic in an amount such that the pH of the cosmetic falls within the above range. A person skilled in the art can appropriately set and adjust such an amount and include it in the cosmetic. For example, the cosmetic may contain at least 0.01% by weight, at least 0.05% by weight, at least 0.1% by weight, at least 0.2% by weight, at least 0.3% by weight, at least 0.5% by weight, at least 1.0% by weight, at least 1.5% by weight, at least 2.0% by weight, at least 3.0% by weight, at least 5.0% by weight, at least 10% by weight, at least 15% by weight, or at least 20% by weight of the pH adjuster based on the total weight of the cosmetic. Also, the amount of the pH adjuster can be, for example, 30% by weight or less, 20% by weight or less, 15% by weight or less, 10% by weight or less, 5.0% by weight or less, 4.0% by weight or less, 3.0% by weight or less, 2.0% by weight or less, 1.0% by weight or less, 0.5% by weight or less based on the total weight of the cosmetic. For example, the cosmetic can contain 0.01 to 20% by weight, 0.1 to 10% by weight, 0.2 to 5.0% by weight, 0.5 to 3.0% by weight, or 1.0 to 2.5% by weight, for example, 0.1 to 0.5% by weight, 0.1 to 1.0% by weight, or 0.1 to 2.0% by weight of the pH adjuster based on the total weight of the cosmetic.

[0033] As described above, in the present invention, when pentylene glycol is used as a preservative, it has been found that a stable cosmetic can be obtained after adding a pH adjuster even when a high concentration of fulvic acid is contained in the cosmetic. The combination of pentylene glycol as a preservative and sodium citrate as a pH adjuster has been found to result in a very stable cosmetic containing a high concentration of fulvic acid.

[0034] The cosmetic of the present invention can contain cosmetic base materials other than pH adjusters and preservatives (hereinafter also referred to as "other cosmetic base materials") as long as the effects of the present invention are not impaired. Such other cosmetic base materials can include components commonly used in cosmetics / cosmetics, for example, components described in JP-A-2017-39669 and JP-A-2017-186305. For example, the cosmetic base materials include powders such as oily components, inorganic pigments, organic pigments, and dyes, and their silicone-treated products and fluorine compound-treated products, surfactants, water-soluble polymers, moisturizing components, humectants, antioxidants, antifoaming agents, fragrances, thickeners, ultraviolet absorbers, and the like.

[0035] As the oily component, for example, regardless of the origin such as animal oil, vegetable oil, synthetic oil, or the properties such as semi-solid oil, liquid oil, volatile oil, hydrocarbons, oils and fats, ester oils, fatty acids, higher alcohols, fluorine-based oils, etc. can be used. Specifically, hydrocarbons such as liquid paraffin, squalane, petrolatum, polyisobutylene, oils and fats such as olive oil, mink oil, macadamia nut oil, esters such as cetyl isooctanoate, isopropyl myristate, isopropyl palmitate, octyldodecyl myristate, neopentyl glycol dioctanoate, jojoba oil, glyceryl tri-2-ethylhexanoate, diisostearyl malate, fatty acids such as isostearic acid, oleic acid, higher alcohols such as oleyl alcohol, isostearyl alcohol, fluorine-based oil agents such as perfluorodecane, perfluorooctane, perfluoropolyether, and oil-soluble beauty components can be mentioned.

[0036] As the powder component, any powder can be used as long as it is generally used in cosmetics. It is not particularly limited by the shape such as plate-like or needle-like, the particle size such as smoke-like, fine particles, pigment grade, or the particle structure such as porous or non-porous. Examples include inorganic powders, lustrous powders, organic powders, pigment powders, metal powders, composite powders, etc. Specifically, colored inorganic pigments such as iron oxide, carbon black, chromium oxide, chromium hydroxide, ultramarine blue, and lapis lazuli; white extender powders such as talc, muscovite, phlogopite, biotite, synthetic mica, sericite, synthetic sericite, barium sulfate, kaolin, silicon carbide, bentonite, smectite, diatomaceous earth, aluminum silicate, magnesium aluminum metasilicate, calcium silicate, barium silicate, magnesium silicate, magnesium carbonate, hydroxyapatite, and boron nitride; lustrous powders such as titanium oxide-coated mica, titanium oxide-coated bismuth oxychloride, iron oxide mica titanium, ultramarine-treated mica titanium, carmine-treated mica titanium, bismuth oxychloride, fish scale foil, polyethylene terephthalate-aluminum-epoxy laminate powder, polyethylene terephthalate-polyolefin laminate film powder, polyethylene terephthalate-polymethyl methacrylate laminate film powder; organic low-molecular-weight powders such as zinc stearate and N-acyl lysine; natural organic powders such as silk powder, cellulose powder, and dextrin powder; organic pigment powders such as C.I. Pigment Red 201, C.I. Pigment Red 202, C.I. Pigment Red 205, C.I. Pigment Red 226, C.I. Pigment Red 228, C.I. Pigment Orange 203, C.I. Pigment Orange 204, C.I. Pigment Blue 404, C.I. Pigment Yellow 401, etc., and zirconium, barium, or aluminum lakes such as C.I. Pigment Red 3, C.I. Pigment Red 104, C.I. Pigment Red 106, C.I. Pigment Orange 205, C.I. Pigment Yellow 4, C.I. Pigment Yellow 5, C.I. Pigment Green 3, C.I. Pigment Blue 1, etc.; metal powders such as aluminum powder, gold powder, and silver powder; composite powders such as fine particle titanium oxide-coated mica titanium, fine particle zinc oxide-coated mica titanium, barium sulfate-coated mica titanium, titanium oxide-containing silicon dioxide, and zinc oxide-containing silicon dioxide; fibers such as nylon, polyester, rayon, and cellulose. These may be surface-treated with fluorine compounds, silicone oils, powders, oils, gelling agents, surfactants, etc. These powders can be used alone or in combination of two or more, and further composite powders can also be used.

[0037] As the surfactant, any surfactant generally used in cosmetics can be used, and examples include nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, and the like.

[0038] Examples of the water-soluble polymer include plant-based polymers such as gum arabic, tragacanth, galactan, carob gum, guar gum, cationized guar gum, karaya gum, carrageenan, pectin, agar, quince seed (medlar), starch (rice, corn, potato, wheat), algocolloid (brown seaweed extract), etc.; microbial-based polymers such as dextran, succinoglucan, pullulan, etc.; animal-based polymers such as collagen, casein, albumin, gelatin, etc.; starch-based polymers such as carboxymethyl starch, methylhydroxypropyl starch, etc.; cellulose-based polymers such as methyl cellulose, nitrocellulose, ethyl cellulose, methylhydroxypropyl cellulose, hydroxyethyl cellulose, sodium cellulose sulfate, hydroxypropyl cellulose, cationized hydroxyethyl cellulose, sodium carboxymethyl cellulose, crystalline cellulose, cellulose powder, etc.; alginic acid-based polymers such as sodium alginate, propylene glycol alginate, etc.; vinyl-based polymers such as polyvinyl methyl ether, carboxyvinyl polymer, alkyl-modified carboxyvinyl polymer, etc.; polyoxyethylene-based polymers; polyoxyethylene-polyoxypropylene copolymer-based polymers; acrylic-based polymers such as sodium polyacrylate, polyethyl acrylate, polyacrylamide, etc.; organic water-soluble polymers such as polyethyleneimine, cationic polymer, etc.; inorganic water-soluble polymers such as bentonite, magnesium aluminum silicate, laponite, hectorite, silica anhydride, etc. One or more of these can be used.

[0039] Examples of the moisturizing ingredients include saccharides, amino acids and their derivatives, peptides, plant extracts, etc., and one or more of them can be used. Here, examples of the amino acids include glycine, alanine, valine, isoleucine, serine, threonine, aspartic acid, glutamic acid, asparagine, glutamine, lysine, hydroxylysine, arginine, cystine, cysteine, acetylcysteine, methionine, phenylalanine, tyrosine, proline, hydroxyproline, ornithine, citrulline, theanine, creatine, creatinine, etc. Examples of the amino acid derivatives include glutathione, pyrrolidone carboxylic acid, N-acylglutamic acid lysine condensate, etc. Examples of the peptides may be derived from any of animals, fish, shellfish, plants, and specifically include collagen and its derivatives or their hydrolysates, elastin and its derivatives or their hydrolysates, keratin and its derivatives or their degradation products, wheat protein and its derivatives or their hydrolysates, soybean protein and its derivatives or their hydrolysates, etc. Examples of the plant extracts include peony, lotus root, Chinese yam, peony root, ginseng, birch, sage, loquat, carrot, aloe, okra, iris, grape, licorice root, loofah, lily, saffron, ginseng, ginger, chickweed, ononis, garlic, capsicum, Chinese quince, torreya, seaweed, etc., which are appropriately extracted with water or an organic solvent.

[0040] Examples of the humectant include glycerin, sorbitol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glucose, xylitol, maltitol, polyethylene glycol, hyaluronic acid (e.g., hydrolyzed hyaluronic acid), chondroitin sulfate, pyrrolidone carboxylate, polyoxyethylene methyl glucoside, polyoxypropylene methyl glucoside, egg yolk lecithin, soybean lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingomyelin lipid, and the like. In one embodiment of the present invention, the cosmetic contains one or more of the above compounds as a humectant. The cosmetic may contain, for example, at least 0.01 wt%, at least 0.05 wt%, at least 0.1 wt%, at least 0.2 wt%, at least 0.3 wt%, at least 0.5 wt%, at least 1.0 wt%, at least 1.5 wt%, at least 2.0 wt%, at least 3.0 wt%, at least 5.0 wt%, at least 10 wt%, at least 15 wt%, at least 20 wt%, at least 30 wt%, or at least 40 wt% of the humectant based on the total weight of the cosmetic. Also, the amount of the humectant may be, for example, 60 wt% or less, 50 wt% or less, 40 wt% or less, 30 wt% or less, 20 wt% or less, 15 wt% or less, 10 wt% or less, 5.0 wt% or less, 4.0 wt% or less, 3.0 wt% or less, 2.0 wt% or less, 1.0 wt% or less, or 0.5 wt% or less based on the total weight of the cosmetic. The cosmetic may contain the humectant in an amount of, for example, 0.01 to 50 wt%, 0.1 to 40 wt%, 0.5 to 30 wt%, or 1 to 20 wt%, for example, 0.01 to 15 wt% or 0.01 to 10 wt% based on the total weight of the cosmetic. When the cosmetic contains a plurality of the above compounds as a humectant, the cosmetic may contain each compound in an amount of, for example, 0.005 to 25 wt%, 0.05 to 20 wt%, 0.25 to 15 wt%, or 0.5 to 10 wt%, for example, 0.005 to 7.5 wt% or 0.005 to 5 wt% based on the total weight of the cosmetic.

[0041] Examples of antioxidants include tocopherol, p-t-butylphenol, butylhydroxyanisole, dibutylhydroxytoluene, phytic acid, and the like.

[0042]

[0043] Examples of fragrances include natural fragrances and synthetic fragrances. For example, natural fragrances include plant fragrances separated from flowers, leaves, woods, fruit peels, etc.; animal fragrances such as musk and civet. Examples of synthetic fragrances include hydrocarbons such as monoterpenes; alcohols such as aliphatic alcohols and aromatic alcohols; aldehydes such as terpene aldehydes and aromatic aldehydes; ketones such as alicyclic ketones; esters such as terpene esters; lactones; phenols; oxides; nitrogen-containing compounds; acetals, and the like.

[0044]

[0045] Examples of ultraviolet absorbers include benzoic acid derivatives, salicylic acid derivatives, cinnamic acid derivatives, dibenzoylmethane derivatives, β,β-diphenylacrylate derivatives, benzophenone derivatives, benzylidene camphor derivatives, phenylbenzimidazole derivatives, triazine derivatives, phenylbenzotriazole derivatives, anthranil derivatives, imidazoline derivatives, benzalmalonate derivatives, 4,4-diarylbutadiene derivatives, and the like.

[0046] The cosmetic can contain various compounds as the cosmetic base material in an amount within the range known to those skilled in the art according to the use of each base material / an amount normally used by those skilled in the art.

[0047] In one embodiment of the present invention, the cosmetic of the present invention contains a humectant, for example, the following group: Glycerin, sorbitol, propylene glycol, dipropylene glycol, 1,3 - butylene glycol, glucose, xylitol, maltitol, polyethylene glycol, hyaluronic acid (for example, hydrolyzed hyaluronic acid), chondroitin sulfate, pyrrolidone carboxylate, polyoxyethylene methyl glucoside, polyoxypropylene methyl glucoside, egg yolk lecithin, soybean lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol and sphingolipids, and contains one or more compounds selected from the group, preferably 1,3 - butylene glycol and / or hyaluronic acid (for example, hydrolyzed hyaluronic acid) as the above - mentioned "other cosmetic base material".

[0048] The cosmetic can contain, based on the total weight of the cosmetic, for example, at least 0.01% by weight, at least 0.05% by weight, at least 0.1% by weight, at least 0.2% by weight, at least 0.3% by weight, at least 0.5% by weight, at least 1.0% by weight, at least 1.5% by weight, at least 2.0% by weight, at least 3.0% by weight, at least 5.0% by weight, at least 10% by weight, at least 15% by weight, at least 20% by weight, at least 30% by weight, at least 40% by weight of the other cosmetic base material. Further, the amount of the other cosmetic base material can be, based on the total weight of the cosmetic, for example, 90% by weight or less, 80% by weight or less, 70% by weight or less, 60% by weight or less, 50% by weight or less, 40% by weight or less, 30% by weight or less, 20% by weight or less, 15% by weight or less, 10% by weight or less, 5.0% by weight or less, 4.0% by weight or less, 3.0% by weight or less, 2.0% by weight or less, 1.0% by weight or less, 0.5% by weight or less. For example, the cosmetic can contain, based on the total weight of the cosmetic, 0.05 to 60% by weight, for example 0.1 to 40% by weight, 0.5 to 30% by weight or 1 to 20% by weight, for example 0.1 to 15% by weight of the other cosmetic base material.

[0049] In addition, the cosmetic of the present invention may contain an active ingredient, such as allantoin, or a cosmetic ingredient other than fulvic acid, such as hydrolyzed hyaluronic acid, as long as it does not interfere with the stability of the high-content fulvic acid. For example, the cosmetic may contain the active ingredient in an amount of at least 0.01 wt%, at least 0.05 wt%, at least 0.1 wt%, at least 0.2 wt%, at least 0.3 wt%, at least 0.5 wt%, at least 1.0 wt%, at least 1.5 wt%, at least 2.0 wt%, at least 3.0 wt%, at least 5.0 wt%, at least 10 wt%, at least 15 wt%, at least 20 wt%, at least 30 wt%, at least 40 wt% based on the total weight of the cosmetic. Also, the amount of the active ingredient can be, for example, 50 wt% or less, 40 wt% or less, 30 wt% or less, 20 wt% or less, 15 wt% or less, 10 wt% or less, 5.0 wt% or less, 4.0 wt% or less, 3.0 wt% or less, 2.0 wt% or less, 1.0 wt% or less, 0.5 wt% or less based on the total weight of the cosmetic. For example, the cosmetic may contain the active ingredient in an amount of 0.01 to 30 wt%, such as 0.05 to 20 wt%, 0.1 to 10 wt%, 0.2 to 5.0 wt%, 0.5 to 3.0 wt% or 1.0 to 2.5 wt% based on the total weight of the cosmetic.

[0050] Preferably, the cosmetic of the present invention contains water. The water is not particularly limited as long as it is usually used for cosmetic production. For example, tap water, purified water, sterilized purified water, hot spring water, deep water, and plant-derived steam-distilled water such as lavender water, rose water, and orange flower water can be mentioned, and one or more of these can be used.

[0051] The cosmetic can contain water in an amount known to those skilled in the art / commonly used by those skilled in the art according to the desired form / dosage form. For example, the cosmetic can contain 0.01 to 99% by weight, such as 0.05 to 90% by weight, 0.1 to 60% by weight or 0.5 to 50% by weight, such as 1.0 to 40% by weight or 5.0 to 30% by weight of water based on the total weight of the cosmetic. For example, water can be added to the components other than water so that the total amount of all components is 100% by weight.

[0052] The cosmetic of the present invention can be prepared, for example, by mixing fulvic acid (for example, a humic extract containing fulvic acid) with a preservative and a pH adjuster, and optionally water and other cosmetic base materials. Therefore, in one embodiment of the present invention, the present invention relates to a cosmetic obtained by mixing fulvic acid (for example, in the form of a humic extract containing fulvic acid), a preservative, a pH adjuster, water and optionally other cosmetic base materials, for example, at room temperature. Those skilled in the art can manufacture the cosmetic according to a method known to those skilled in the art for the desired form / dosage form.

[0053] The above components may be mixed simultaneously, or each component can be mixed in any order. However, in the present invention, it has also been found that when manufacturing the cosmetic, the highest stability can be shown when pentylene glycol as a preservative is added to and mixed with the mixture after mixing fulvic acid with water.

[0054] Therefore, in one embodiment of the present invention, the present invention relates to a method for manufacturing a cosmetic, comprising the following steps: a) adding and mixing fulvic acid to water; b) adding and mixing a preservative to the mixture obtained in step a); c) adding and mixing a pH adjuster to the mixture obtained in step b) to adjust the pH of the mixture to 4.0 to 6.5 to obtain a cosmetic. The present invention relates to the above manufacturing method.

[0055] In the above manufacturing method, optionally, other cosmetic base materials (cosmetic base materials other than preservatives and pH adjusters) as described above may be added. Such other cosmetic base materials can be added at any time, but are preferably added between steps b) and c). In the present invention, it has also been found that in such an addition order, a cosmetic showing better stability can be obtained. Therefore, in one embodiment of the present invention, the manufacturing method further comprises the following steps: d) adding and mixing other cosmetic base materials (cosmetic base materials other than preservatives and pH adjusters), preferably included between steps b) and c).

[0056] In these embodiments, preferably, the fulvic acid is derived from the above-mentioned humic extract. Preferably, the fulvic acid is added in the form of the above-mentioned humic extract, and more preferably, the fulvic acid is added in an amount such that the content of fulvic acid in the cosmetic is at least 1% by weight based on the total weight of the cosmetic. Also, the preservative is preferably L-ascorbic acid or pentylene glycol, more preferably pentylene glycol. Preferably, the pH adjuster is citric acid or an acceptable salt thereof in the cosmetic, such as an alkali metal salt, and more preferably, the pH adjuster is sodium citrate.

[0057] In the above embodiments, the addition and mixing of the components in steps a), b), c), and d) can be carried out, for example, at room temperature (typically about 25°C), and the mixing can be carried out, for example, under stirring using a stirrer. The appropriate blending amounts of each component are as described above for the cosmetic.

[0058] When the cosmetic of the present invention is manufactured on an industrial scale, the manufacturing can be carried out according to procedures and methods known to those skilled in the art regarding industrial-scale manufacturing. Depending on the type and dosage form of the desired cosmetic, for example, the cosmetic can be appropriately manufactured through any combination of procedures and processes such as raw material procurement, weighing, mixing, filtration, cooling, filling, packaging, labeling, test inspection, storage, and determination of shipment feasibility, which will be understood by those skilled in the art.

[0059] In another embodiment of the present invention, the present invention relates to a cosmetic obtained by the above manufacturing method.

[0060] The present invention will be described in more detail by the following examples, but the present invention is not limited to these examples.

Example

[0061] In order to produce a safe and stable cosmetic (here, a lotion) by blending a preservative, compatibility with several preservatives was examined and a stability test was conducted. The test was carried out at room temperature (about 25°C).

[0062] In the test, the following components were used: 1) Fulvic acid As the fulvic acid, fulvic acid (stock solution) (Lot No. 80040822) sold by Nippon Organic Mineral Co., Ltd. was used. This is an extraction and purification solution with RO water from an ancient plant deposit layer (humic shale) in Utah, USA. The main component characteristics of the fulvic acid (stock solution) (hereinafter, also referred to as "fulvic acid stock solution") are shown below.

[0063]

Table 1

[0064] 2) Preservative · Phenoxyethanol · 1,2 - Hexanediol · Caprylyl glycol · L - Ascorbic acid · Pentylene glycol 3) pH adjuster · Sodium citrate 4) Other cosmetic base materials · BG (humectant) · Hydrolyzed hyaluronic acid (humectant) 5) Active ingredient · Allantoin (skin protectant) 6) Water In addition to the above components, water was added to make the total amount of components 100% by weight.

[0065] Example 1 As a result of formulating a fabric containing fulvic acid and the preservative phenoxyethanol (a mixture of an appropriate amount of allantoin as an active ingredient, BG and hydrolyzed hyaluronic acid as other cosmetic base materials, and water), even with a trace addition of 0.01% by weight of the fulvic acid stock solution, precipitation and floating substances occurred in the cosmetic fabric one day after formulation. With the increase in the formulation concentration of fulvic acid to 0.03% by weight and 0.05% by weight, the change in the cosmetic fabric was significant immediately after formulation.

[0066] Example 2 The preservative was changed from phenoxyethanol to the same amount (by weight) of 1,2 - hexanediol, and tests were conducted with 0.01% by weight, 0.03% by weight, and 0.05% by weight of the fulvic acid stock solution. Unlike phenoxyethanol, no modulation occurred in the fabric immediately after formulation, but sediment was generated after observing for 2 or 3 days.

[0067] Example 3 The preservative was changed from 1,2 - hexanediol to the same amount (by weight) of caprylyl glycol, and when tested, no change occurred immediately after formulation even with 1% by weight, 10% by weight, and 30% by weight of the fulvic acid stock solution. However, after 2 days, floating substances like oil floated on the surface of the fabric. This is considered to be due to the preservative not being completely dissolved or some component being decomposed by chelation with fulvic acid.

[0068] Example 4 The preservative was changed to the same amount (by weight) of L - ascorbic acid as in Examples 1 - 3, and when tested, no change occurred immediately after formulation even with 1% by weight, 10% by weight, and 30% by weight of the fulvic acid stock solution. No precipitation or floating substances were observed even after observing for 2 weeks, so Na citrate was formulated for pH adjustment, but turbidity appeared in the fabric immediately.

[0069] Example 5 The preservative was changed to pentylene glycol in the same amount (weight %) as in Example 4, and tests were conducted with formulations containing 1 wt%, 10 wt%, 30 wt%, 50 wt%, and 90 wt% of the fulvic acid stock solution. In any of the formulations, no precipitates or floating substances were observed after two weeks of observation, so sodium citrate was added for pH adjustment, but no color change was observed in the fabric. By adding sodium citrate, the pH was adjusted to 4.5 - 6.0.

[0070] As described above, containing 1 wt% or more of fulvic acid in cosmetics is a high formulation, and a formulation of 90 wt% of the fulvic acid stock solution as in Example 5 (fulvic acid equivalent concentration: about 3.6 wt%) is a considerably high formulation as a formulation of cosmetic ingredients. In the present invention, it has been found that by using a specific preservative and combining it with a pH adjuster (preferably citric acid or an acceptable salt thereof in cosmetics), a cosmetic containing such an extremely high amount of fulvic acid stably can be produced. Such a cosmetic is stabilized without chelation, and furthermore, no color change such as insufficient dissolution or turbidity occurs in the cosmetic.

Claims

1. A cosmetic containing at least 1% by weight of fulvic acid based on the total weight of the cosmetic.

2. The cosmetic according to Claim 1, having a pH of 4.0 to 6.

5.

3. The cosmetic according to Claim 1 or 2, further containing pentylene glycol.

4. The cosmetic according to Claim 3, further containing a pH adjuster.

5. The cosmetic according to Claim 4, wherein the pH adjuster is citric acid or a cosmetically acceptable salt thereof.

6. The cosmetic according to Claim 1 or 2, wherein the fulvic acid is derived from a humic extract.

7. The cosmetic according to Claim 1, in liquid form.

8. The cosmetic according to Claim 1, selected from the group consisting of beauty essences, moisturizing lotions, softening lotions, astringent lotions, skin care cosmetics, farming cosmetics, body cosmetics, base cosmetics, foundations, primer creams, face powders, and makeup cosmetics.

9. A method for manufacturing a cosmetic, comprising the following steps: a) adding and mixing fulvic acid in water; b) adding and mixing a preservative to the mixture obtained in step a); c) adjusting the pH of the mixture to 4.0 to 6.5 by adding and mixing a pH adjuster to the mixture obtained in step b) to obtain a cosmetic. The manufacturing method as described above.

10. The manufacturing method according to Claim 9, wherein the preservative is pentylene glycol and the pH adjuster is citric acid or a cosmetically acceptable salt thereof.

11. The manufacturing method according to Claim 9, wherein the cosmetic contains at least 1% by weight of fulvic acid based on the total weight of the cosmetic.

12. The manufacturing method according to Claim 9, wherein the fulvic acid is added in the form of a humic extract containing fulvic acid.