Method for controlling harmful arthropods using heterocyclic compound
The use of a heterocyclic compound represented by Formula (I) or its derivatives effectively addresses the limitations of current methods for controlling harmful arthropods, offering a targeted and efficient solution.
Patent Information
- Application Number
- JP2025036251
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2025-03-07
- Publication Date
- 2025-06-10
AI Technical Summary
Current methods for controlling harmful arthropods are inadequate, as existing compounds may have unintended effects or limited efficacy.
A method involving the application of a heterocyclic compound represented by Formula (I) or its N-oxide, or a salt thereof, to harmful arthropods, their habitats, plants, or cultivation carriers, such as soil.
This method effectively controls harmful arthropods by utilizing a specific heterocyclic compound, providing a targeted and potentially more effective solution compared to existing approaches.
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Figure 2025087855000001 
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Figure 2025087855000003
Abstract
Description
Technical Field
[0001] The present invention relates to a method for controlling harmful arthropods using a heterocyclic compound.
Background Art
[0002] So far, various compounds have been studied for the purpose of controlling harmful arthropods. On the other hand, Patent Document 1 describes that a certain heterocyclic compound is useful for the treatment of malignant tumors.
Prior Art Documents
Patent Documents
[0003]
Patent Document 1
Summary of the Invention
Problems to be Solved by the Invention
[0004] An object of the present invention is to provide a method for controlling harmful arthropods using a heterocyclic compound.
Means for Solving the Problems
[0005] The present invention is as follows.
[0006] 〔1〕 Formula (I)
Chemical Formula
Chemical formula
Chemical formula
Chemical formula
Chemical formula
Chemical formula
Advantages of the Invention
[0007] According to the present invention, harmful arthropods can be controlled.
Modes for Carrying Out the Invention
[0008] The substituents in the present invention will be described. The halogen atom means a fluorine atom, a chlorine atom, a bromine atom, or an iodine atom. When substituted with two or more halogen atoms or substituents, those halogen atoms or substituents may be the same or different from each other. The notation "CX-CY" in this specification means that the number of carbon atoms is from X to Y. For example, the notation "C1-C6" means that the number of carbon atoms is from 1 to 6. The chain hydrocarbon group represents an alkyl group, an alkenyl group, or an alkynyl group. Examples of the alkyl group include a methyl group, an ethyl group, a propyl group, an isopropyl group, a 1,1-dimethylpropyl group, a 1,2-dimethylpropyl group, a 1-ethylpropyl group, a butyl group, a sec-butyl group, a tert-butyl group, a pentyl group, and a hexyl group. Examples of the alkenyl group include a vinyl group, a 1-propenyl group, a 2-propenyl group, a 1-methyl-1-propenyl group, a 1-methyl-2-propenyl group, a 1,2-dimethyl-1-propenyl group, a 1-ethyl-2-propenyl group, a 3-butenyl group, a 4-pentenyl group, and a 5-hexenyl group. Examples of the alkynyl group include an ethynyl group, a 1-propynyl group, a 2-propynyl group, a 1-methyl-2-propynyl group, a 1,1-dimethyl-2-propynyl group, a 1-ethyl-2-propynyl group, a 2-butynyl group, a 4-pentynyl group, and a 5-hexynyl group. Examples of the alkoxy group include a methoxy group, an ethoxy group, a propoxy group, an isopropoxy group, a butoxy group, a tert-butoxy group, a pentyloxy group, and a hexyloxy group. Examples of the 5- or 6-membered aromatic heterocyclic group include a pyrazolyl group, an imidazolyl group, a triazolyl group, a tetrazolyl group, an oxazolyl group, an isoxazolyl group, a thiazolyl group, an isothiazolyl group, an oxadiazolyl group, a thiadiazolyl group, a pyridyl group, a pyridazinyl group, a pyrimidinyl group, and a pyrazinyl group. The 5- or 6-membered heterocyclic group represents a 5- or 6-membered aromatic heterocyclic group or a 5- or 6-membered non-aromatic heterocyclic group. Examples thereof include a pyrrolyl group, a furyl group, a thienyl group, a pyrazolyl group, an imidazolyl group, a triazolyl group, a tetrazolyl group, an oxazolyl group, an isoxazolyl group, a thiazolyl group, an isothiazolyl group, an oxadiazolyl group, a thiadiazolyl group, a pyridyl group, a pyridazinyl group, a pyrimidinyl group, a pyrazinyl group, a triazinyl group, a tetrazinyl group, a pyrrolidinyl group, an imidazolinyl group, an imidazolidinyl group, a piperidinyl group, a tetrahydropyrimidinyl group, a hexahydropyrimidinyl group, a piperazinyl group, an oxazolidinyl group, an isoxazolidinyl group, a 1,3-oxazinanyl group, a morpholinyl group, a thiazolidinyl group, an isothiazolidinyl group, a 1,3-thiazinanyl group, and a thiomorpholinyl group. Examples of the 5- or 6-membered non-aromatic heterocyclic ring include a dihydrofuran ring, a dihydrothiophene ring, a dihydropyrrole ring, a 1,3-dioxole ring, a pyran ring, and a dihydropyran ring. Examples of the 5- or 6-membered aromatic heterocyclic ring include a furan ring, a thiophene ring, a pyrrole ring, a pyrazole ring, an imidazole ring, an oxazole ring, an isoxazole ring, a thiazole ring, an isothiazole ring, a triazole ring, an oxadiazole ring, a thiadiazole ring, a pyridine ring, a pyridazine ring, a pyrimidine ring, and a pyrazine ring. Examples of the 9-membered aromatic heterocyclic group include a benzoxazolyl group, a benzoisoxazolyl group, a benzothiazolyl group, a benzoisothiazolyl group, and a triazolopyridyl group. Examples of the 10-membered aromatic heterocyclic group include a quinolyl group, an isoquinolyl group, a quinazolinyl group, and a quinazolonyl group. The (C3-C6 cycloalkyl)C1-C3 alkyl group optionally substituted with one or more halogen atoms means a group in which (C3-C6 cycloalkyl) and / or (C1-C3 alkyl) may have one or more halogen atoms. Examples include cyclopropylmethyl group, cyclopropylethyl group, (2,2-difluorocyclopropyl)methyl group, 2-cyclopropyl-1,1,2,2-tetrafluoroethyl group, and 2-(2,2-difluorocyclopropyl)-1,1,2,2-tetrafluoroethyl group. The phenyl C1-C3 alkyl group {wherein the phenyl moiety in the phenyl C1-C3 alkyl group may be substituted with one or more substituents selected from Group B} means, for example, benzyl group, 2-fluorobenzyl group, 4-chlorobenzyl group, 4-(trifluoromethyl)benzyl group, and 2-[4-(trifluoromethyl)phenyl]ethyl group. Examples of the 3- to 6-membered non-aromatic heterocyclic group include oxetanyl group, pyrrolidinyl group, 2-oxopyrrolidinyl group, 2-oxoimidazolidinyl group, 3,4,5,6-tetrahydro-2-pyrimidinyl group, tetrahydrofuranyl group, piperidyl group, tetrahydropyranyl group, isoxazolidinyl group, and morpholinyl group. Examples of the alkylsulfonyl group include methylsulfonyl group, ethylsulfonyl group, propylsulfonyl group, and isopropylsulfonyl group.
[0009] Examples of the cycloalkyl group include cyclopropyl group, cyclobutyl group, cyclopentyl group, and cyclohexyl group.
[0010] This compound may have one or more stereoisomers. Examples of stereoisomers include enantiomers, diastereomers, atropisomers, and geometric isomers. This compound includes each stereoisomer and a mixture of stereoisomers in any ratio.
[0011] The compound represented by formula (I) or its N-oxide may form an acid addition salt. Examples of the acid that forms the acid addition salt include inorganic acids such as hydrogen chloride, phosphoric acid, sulfuric acid, and organic acids such as acetic acid, trifluoroacetic acid, benzoic acid, p-toluenesulfonic acid. The acid addition salt can be obtained, for example, by mixing the compound represented by formula (I) or its N-oxide with an acid.
[0012] Next, the production method of this compound will be described.
[0013] Production Method 1 The compound represented by formula (I-1) (hereinafter referred to as compound (I-1)) can be produced by reacting the compound represented by formula (I-2) (hereinafter referred to as compound (I-2)) with an acid to deprotect the tert-butoxycarbonyl group, obtaining a deprotected product, and then reacting the deprotected product with the compound represented by formula (M-a) (hereinafter referred to as compound (M-a)).
Chemical formula
[0014] Next, the reaction between the deprotected product and compound (M-a) will be described. The reaction is usually carried out in a solvent. Examples of the solvent include ethers, halogenated hydrocarbons, aromatic hydrocarbons, nitriles, aprotic polar solvents, and mixtures of two or more of these. The reaction can be carried out, for example, by mixing the deprotected product of compound (I-2) and compound (M-a). A base can be used in the reaction as needed. Examples of the base include organic bases such as triethylamine, N,N-diisopropylethylamine, pyridine, and 4-(dimethylamino)pyridine (hereinafter referred to as organic bases). When a base is used in the reaction, the base is usually used in a ratio of 1 to 10 moles per 1 mole of compound (I-2). In the reaction, compound (M-a) is usually used in a ratio of 1 to 2 moles per 1 mole of compound (I-2). The reaction temperature is usually in the range of -20 to 200 °C. The reaction time is usually in the range of 0.1 to 24 hours. After the reaction is completed, water is added to the reaction mixture, extraction is carried out with an organic solvent, and post-treatment operations such as drying and concentrating the organic layer are performed to obtain compound (I-1). Compound (M-a) is a commercially available compound or can be produced using known methods.
[0015] Production Method 2 Compound (I-1) can also be produced by reacting compound (I-2) with an acid to deprotect the tert-butoxycarbonyl group to obtain a deprotected product, and then reacting the deprotected product with a compound represented by formula (M-b) (hereinafter referred to as compound (M-b)) in the presence of a condensing agent.
Chemical formula
[0016] Next, the reaction between the deprotected product and compound (M-b) will be described. The reaction is usually carried out in a solvent. Examples of the solvent include ethers; halogenated hydrocarbons; aromatic hydrocarbons; nitriles; esters such as ethyl acetate and butyl acetate (hereinafter referred to as esters); aprotic polar solvents; nitrogen-containing aromatic compounds such as pyridine, picoline, lutidine, and quinoline (hereinafter referred to as nitrogen-containing aromatic compounds); and mixtures of two or more of these. The reaction can be carried out, for example, by mixing the deprotected product of compound (I-2), compound (M-b), and a condensing agent. Examples of the condensing agent used in the reaction include carbodiimides such as 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide hydrochloride and 1,3-dicyclohexylcarbodiimide. A catalyst can be used in the reaction as needed. Examples of the catalyst include 1-hydroxybenzotriazole. When a catalyst is used in the reaction, the catalyst is usually used in a proportion of 0.01 to 0.5 mol per 1 mol of compound (I-2). A base can be used in the reaction as needed. Examples of the base include organic bases. When a base is used in the reaction, the base is usually used in a proportion of 1 to 5 mol per 1 mol of compound (I-2). In the reaction, per 1 mol of compound (I-2), compound (M-b) is usually used in a proportion of 1 to 2 mol, and the condensing agent is usually used in a proportion of 1 to 5 mol. The reaction temperature is usually in the range of -20 to 200 °C. The reaction time is usually in the range of 0.1 to 48 hours. After completion of the reaction, water is added to the reaction mixture, extraction is performed with an organic solvent, and post-treatment operations such as drying and concentrating the organic layer are carried out to obtain compound (I-1). Compound (M-b) is a commercially available compound or can be produced using known methods.
[0017] Production Method 3 Compound (I-1) can also be produced by reacting a compound represented by formula (I-3) (hereinafter referred to as compound (I-3)) with compound (M-a). [Chemical formula] [In the formula, the symbols have the same meanings as described above.] The reaction is usually carried out in a solvent. Examples of the solvent include ethers; halogenated hydrocarbons; nitriles; aromatic hydrocarbons; aprotic polar solvents, and mixtures of two or more of these. The reaction can use a base as needed. Examples of the base include organic bases; and alkali metal carbonates such as sodium carbonate, potassium carbonate, cesium carbonate, etc. (hereinafter referred to as alkali metal carbonates). In the reaction, compound (M-a) is usually used in a ratio of 1 to 10 moles per 1 mole of compound (I-3). The reaction temperature is usually in the range of 0°C to 200°C. The reaction time is usually in the range of 0.1 to 48 hours. After the reaction is completed, water is added to the reaction mixture, followed by extraction with an organic solvent, and post-treatment operations such as drying and concentrating the organic layer to obtain compound (I-1).
[0018] Production Method 4 Compound (I-1) can also be produced by reacting compound (I-3) with compound (M-b) in the presence of a condensing agent.
Chemical formula
[0019] The production method of the production intermediate is described below.
[0020] Reference Production Method 1 Compound (I-3) can be produced from compound (I-2).
Chemical formula
[0021] Reference Production Method 2 The compound represented by compound (I-1A) (hereinafter referred to as compound (I-1A)) can be produced by reacting the compound represented by formula (I-2A) (hereinafter referred to as compound (I-2A)) with the compound represented by formula (IM-a) (hereinafter referred to as compound (IM-a)).
Chemical formula
[0022] Reference Production Method 3 Compound (I-2A) can be produced by reacting a compound represented by formula (I-3A) (hereinafter referred to as compound (I-3A)) with a compound represented by compound (IM-b) (hereinafter referred to as compound (IM-b)).
Chemical formula
[0023] This compound can be mixed or used in combination with one or more components (hereinafter referred to as "this component") selected from the group consisting of the following groups (a), (b), (c), (d), (e), (f), (g), (h), (i), and (j). The above-mentioned mixing or combined use means using this compound and this component simultaneously, separately, or at intervals. When this compound and this component are used simultaneously, this compound and this component may be contained in separate formulations or in one formulation. One aspect of the present invention is a composition (hereinafter referred to as "Composition A") containing one or more components (i.e., this component) selected from the group consisting of groups (a), (b), (c), (d), (e), (f), (g), (h), (i), and (j), and this compound.
[0024] Group (a) includes acetylcholinesterase inhibitors (e.g., carbamate insecticides, organophosphorus insecticides), GABAergic chloride ion channel blockers (e.g., phenylpyrazole insecticides), sodium channel modulators (e.g., pyrethroid insecticides), nicotinic acetylcholine receptor competitive modulators (e.g., neonicotinoid insecticides), nicotinic acetylcholine receptor allosteric modulators, glutamate-gated chloride ion channel allosteric modulators (e.g., macrolide insecticides), It consists of juvenile hormone mimics, multi-site inhibitors, chordotonal organ TRPV channel modulators, mite growth inhibitors, mitochondrial ATP synthase inhibitors, oxidative phosphorylation uncouplers, nicotinic acetylcholine receptor channel blockers (e.g., nereistoxin-based insecticides), chitin biosynthesis inhibitors, molting inhibitors, ecdysone receptor agonists, octopamine receptor agonists, inhibitors of mitochondrial electron transport system complexes I, II, III, and IV, voltage-dependent sodium channel blockers, acetyl-CoA carboxylase inhibitors, ryanodine receptor modulators (e.g., diamide-based insecticides), chordotonal organ modulators, and other insecticidal, acaricidal, and nematicidal active ingredients. These are described in the classification based on the mode of action of IRAC.
[0025] Group (b) consists of nucleic acid synthesis inhibitors (e.g., phenylamide-based fungicides, acyl amino acid-based fungicides), cell division and cytoskeleton inhibitors (e.g., MBC fungicides), respiration inhibitors (e.g., QoI fungicides, QiI fungicides), amino acid synthesis and protein synthesis inhibitors (e.g., anilinopyrimidine-based fungicides), signal transduction inhibitors, lipid synthesis and membrane synthesis inhibitors, sterol biosynthesis inhibitors (e.g., DMI fungicides such as triazoles), cell wall biosynthesis inhibitors, melanin synthesis inhibitors, plant defense inducers, other site of action contact active fungicides, microbial fungicides, and other fungicidal active ingredients. These are described in the classification based on the mode of action of FRAC.
[0026] Group (c) is a group of plant growth regulating components.
[0027] Group (d) is a group of phytotoxicity reducing components.
[0028] Group (e) is a group of synergists.
[0029] Group (f) is a group of repellent components consisting of bird repellent components, insect repellent components, and animal repellent components.
[0030] Group (g) is a group of molluscicidal components.
[0031] Group (h) is a group of information - transmitting substances composed of pheromones and allelochemicals utilized by insects.
[0032] Group (i) is a group consisting of acetyl - CoA carboxylase (ACCase) inhibitors, acetolactate synthase (ALS) inhibitors, photosynthesis (photosystem II) inhibitors, photosystem I electron transfer agents, protoporphyrinogen oxidase (PPO) inhibitors, phytoene desaturase system (PDS) inhibitors, 4 - hydroxyphenylpyruvate dioxygenase (4 - HPPD) inhibitors, carotenoid biosynthesis inhibitors, EPSP synthase inhibitors, glutamine synthase inhibitors, dihydropteroate (DHP) synthase inhibitors, microtubule polymerization inhibitors, mitosis / microtubule formation inhibitors, very - long - chain fatty acid (VLCFA) inhibitors, cellulose synthesis inhibitors, uncoupling agents, lipid synthesis inhibitors, indole - acetic - acid - like activators, auxin transport inhibitors, and other herbicidal active ingredients. These are described in the classification based on the mode of action of HRAC.
[0033] Group (j) is a group of biocontrol materials composed of bacteria, fungi, yeasts, protozoa, viruses, natural products, insects, mites, and mollusks that have control effects on pests (such as insecticidal activity, acaricidal activity, nematicidal activity, bactericidal activity, etc.), herbicidal activity, or plant - growth - regulating effects on rhizobia, mycorrhizal fungi, etc. Specifically, group (j) is represented by subgroup (j - 1): bacteria, subgroup (j - 2): fungi and yeasts, subgroup (j - 3): protozoa, subgroup (j - 4): viruses, subgroup (j - 5): nematodes, subgroup (j - 6): natural products, subgroup (j - 7): insects, subgroup (j - 8): mites, and subgroup (j - 9): mollusks.
[0034] Examples of combinations of the present component and the present compound are described below. For example, alanycarb + SX means the combination of alanycarb and SX. Note that the abbreviation SX means any one of the compounds described in the compound groups SX1 to SX540 or any one of the compounds 1 to 21 of the present compound. Further, all of the present components described below are known components, and can be obtained from commercially available preparations or produced by known methods. When the present component is a microorganism, it can also be obtained from a microorganism depository institution. The numbers in parentheses represent CAS RN (registered trademark).
[0035] Combination of the present component and the present compound in the above group (a): Abamectin + SX, Acephate + SX, Acequinocyl + SX, Acetamiprid + SX, Acetic acid + SX, Acetoprole + SX, Acrinathrin + SX, Acynonapyr + SX, Afidopyropen + SX, Afoxolaner + SX, Alanycarb + SX, Aldicarb + SX, Allethrin + SX, Alpha-cypermethrin + SX, Alpha-endosulfan + SX, Aluminium phosphide + SX, Amitraz + SX, Azamethiphos + SX, Azinphos-ethyl + SX, Azinphos-methyl + SX, Azocyclotin + SX, Bendiocarb + SX, Benfluthrin + SX, Benfuracarb + SX, Bensultap + SX, Bentioflumin + SX, Benzoic acid + SX, Benzoximate + SX, Benzpyrimoxan + SX, Beta-cyfluthrin + SX, Beta-cypermethrin + SX, Bifenazate + SX, Bifenthrin + SX, Bilobalide + SX, Bioallethrin + SX, Bioresmethrin + SX,Bistrifluron + SX, Bisulflufen + SX, Borax + SX, Boric Acid + SX, Broflanilide + SX, Bromopropylate + SX, Buprofezin + SX, Butyric Acid + SX, Butocarboxim + SX, Butoxycarboxim + SX, Cadusafos + SX, Calcium Phosphide + SX, Carbaryl + SX, Carbofuran + SX, Carbosulfan + SX, Cartap Hydrochloride + SX, Cartap + SX, Chinomethionat + SX, Chlorantraniliprole + SX, Chlordane + SX, Chlorethoxyfos + SX, Chlorfenapyr + SX, Chlorfenvinphos + SX, Chlorfluazuron + SX, Chlormephos + SX, Chloropicrin + SX, Chlorpyrifos + SX, Chlorpyrifos - methyl + SX, Chromafenozide + SX, Citric Acid + SX, Clofentezine + SX, Clothianidin + SX, Coumaphos + SX, Cryolite + SX, Cyanophos + SX,Cyantraniliprole + SX, Cybenzoxasulfyl + SX, Cyclaniliprole + SX, Cyclobutrifluram + SX, Cycloprothrin + SX, Cycloxaprid + SX, Cyenopyrafen + SX, Cyetpyrafen + SX, Cyflumetofen + SX, Cyfluthrin + SX, Cyhalodiamide + SX, Cyhalothrin + SX, Cyhexatin + SX, Cypermethrin + SX, Cyphenothrin + SX, Cyproflanilide + SX, Cyromazine + SX, Dazomet + SX, Deltamethrin + SX, Demeton-S-methyl + SX, Diafenthiuron + SX, Diatomaceous earth + SX, Diazinon + SX, Dichlorvos + SX, Dicloromezotiaz + SX, Dicofol + SX, Dicrotophos + SX, Diflovidazin + SX, Diflubenzuron + SX, Dimefluthrin + SX, Dimethoate + SX, Dimethylvinphos + SX, Dimpropyridaz + SX, Dinotefuran + SX, Disodium octaborate + SX,Disulfoton + SX, DNOC (2-methyl-4,6-dinitrophenol) + SX, Doramectin + SX, Emamectin-benzoate + SX, Empenthrin + SX, Endosulfan + SX, EPN (O-ethyl O-(4-nitrophenyl) phenylphosphonothioate) + SX, Epsilon-metofluthrin + SX, Epsilon-momfluorothrin + SX, Esfenvalerate + SX, Ethiofencarb + SX, Ethion + SX, Ethiprole + SX, Ethoprophos + SX, Etofenprox + SX, Etoxazole + SX, Famphur + SX, Fenamiphos + SX, Fenazaquin + SX, Fenbutatin oxide (oxidized) + SX, Fenitrothion + SX, Fenmezoditiaz + SX, Fenobucarb + SX, Fenoxycarb + SX, Fenpropathrin + SX, Fenpyroximate + SX, Fenthion + SX, Fenvalerate + SX, Fipronil + SX, Flometoquin + SX, Flonicamid + SX, Fluacrypyrim + SX, Fluazaindolizine + SX,Fluazuron + SX, Flubendiamide + SX, Fluchlordiniliprole + SX, Flucycloxuron + SX, Flucythrinate + SX, Fluensulfone + SX, Flufenoprox + SX, Flufenoxuron + SX, Flufiprole + SX, Flumethrin + SX, Flupentiofenox + SX, Flupyradifurone + SX, Flupyrimin + SX, Flupyroxystrobin + SX, Fluralaner + SX, Fluvalinate + SX, Fluxametamide + SX, Formetanate + SX, Fosthiazate + SX, Fumaric acid + SX, Furamethrin + SX, Furathiocarb + SX, Gamma-cyhalothrin + SX, Halfenprox + SX, Halofenozide + SX, Heptafluthrin + SX, Heptenophos + SX, Hexaflumuron + SX, Hexythiazox + SX, Potassium salt of hop beta acid + SX, Hydramethylnon + SX, Imicyafos + SX, Imidacloprid + SX,Imidaclothiz + SX, Imiprothrin + SX, Indazapyroxamet + SX, Indoxacarb + SX, Isocycloseram + SX, Isofenphos + SX, Isoflualanam + SX, Isoprocarb + SX, Isopropyl - O - (methoxyaminothiophosphoryl) salicylate + SX, Isoxathion + SX, Kadethrin + SX, Kappa - tefluthrin + SX, Kappa - bifenthrin + SX, Lactic acid + SX, Lambda - cyhalothrin + SX, Lavandulyl senecioate + SX, Ledprona + SX, Lenoremycin + SX, Lepimectin + SX, Lime sulfur + SX, Lotilaner + SX, Lufenuron + SX, Machine oil + SX, Malathion + SX, Malic acid + SX, Mecarbam + SX, Meperfluthrin + SX, Metaflumizone + SX, Metam + SX, Methamidophos + SX, Methidathion + SX, Methiocarb + SX, Methomyl + SX, Methoxychlor + SX,Methoxyfenozide + SX, Methyl bromide + SX, Metofluthrin + SX, Metolcarb + SX, Metoxadiazone + SX, Mevinphos + SX, Milbemectin + SX, Milbemycin oxime + SX, Mivorilaner + SX, Modoflaner + SX, Momfluorothrin + SX, Monocrotophos + SX, Moxidectin + SX, Naled + SX, Nicofluprole + SX, Nicotine + SX, Nicotine-sulfate + SX, Nitenpyram + SX, Novaluron + SX, Noviflumuron + SX, Omethoate + SX, Organic acid +SX, Oxalic acid +SX, Oxamyl + SX, Oxazosulfyl + SX, Oxydemeton-methyl + SX, Parathion + SX, Parathion-methyl + SX, Permethrin + SX, Phenothrin + SX, Phenthoate + SX, Phorate + SX, Phosalone + SX, Phosmet + SX, Phosphamidon + SX, Phosphine + SX, Phoxim + SX, Pioxaniliprole + SX, Piperflanilide + SX, Pirimicarb + SX, Pirimiphos-methyl + SX, Prallethrin + SX, Profenofos + SX, Profluthrin + SX, Propionic acid + SX, Propargite + SX, Propetamphos + SX, Propoxur + SX, Propylene glycol alginate + SX, Prothiofos + SX, Pyflubumide + SX, Pymetrozine + SX, Pyraclofos + SX, Pyrethrins + SX, Pyridaben + SX, Pyridalyl + SX, Pyridaphenthion + SX, Pyrifluquinazone + SX, Pyrimidifen + SX, Pyriminostrobin + SX, Pyriprole + SX, Pyriproxyfen + SX, Quinalphos + SX,Resmethrin + SX, Sarolaner + SX, Selamectin + SX, Sigma-cypermethrin + SX, Silafluofen + SX, Sodium borate + SX, Sodium metaborate + SX, Spidoxamat + SX, Spinetoram + SX, Spirobudifen + SX, Spirodiclofen + SX, Spiromesifen + SX, Spiropidion + SX, Spirotetramat + SX, Sulfiflumin + SX, Sulfluramid + SX, Sulfotep + SX, Sulfoxaflor + SX, Sulfoxamyl + SX, Sulfur + SX, Sulfuryl fluoride + SX, Tartar emetic + SX, Tartaric acid + SX, Tau-fluvalinate + SX, Tebufenozide + SX, Tebufenpyrad + SX, Tebupirimfos + SX, Teflubenzuron + SX, Tefluthrin + SX, Temephos + SX, Terbufos + SX, Tetrachlorantraniliprole + SX, Tetrachlorvinphos + SX, Tetradifon + SX, Tetramethrin + SX,Tetramethylfluthrin + SX, Tetraniliprole + SX, Theta-cypermethrin + SX, Thiacloprid + SX, Thiamethoxam + SX, Thiocyclam + SX, Thiodicarb + SX, Thiofanox + SX, Thiometon + SX, Thiosultap-disodium + SX, Thiosultap-monosodium + SX, Tigolaner + SX, Tiorantraniliprole + SX, Tioxazafen + SX, Tolfenpyrad + SX, Tralomethrin + SX, Transfluthrin + SX, Triazamate + SX, Triazophos + SX, Trichlorfon + SX, Trifluenfuronate + SX, Triflumezopyrim + SX, Triflumuron + SX, Trimethacarb + SX, Trioxyflanilide + SX, Tyclopyrazoflor + SX, Umifoxolaner + SX, Vadescana + SX, Vamidothion + SX, XMC (3,5-dimethylphenyl N-methylcarbamate) + SX, Xylylcarb + SX, Zeta-cypermethrin + SX,Zinc phosphide + SX, N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-N-ethyl-3-(3,3,3-trifluoropropanesulfinyl)propanamide (1477923-37-7) + SX, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide (1241050-20-3) + SX, 3-methoxy-N-(5-{5-(trifluoromethyl)-5-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}indan-1-yl)propanamide (1118626-57-5) + SX, 2-({2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}imino)-3-(2,2,2-trifluoroethyl)-1,3-thiazolidin-4-one (1445683-71-5) + SX, N-{4-chloro-3-[(1-cyanocyclopropyl)carbamoyl]phenyl}-1-methyl-4-(methanesulfonyl)-3-(1,1,2,2,2-pentafluoroethyl)-1H-pyrazole-3-carboxamide (1400768-21-9) + SX, N-[3-chloro-1-(pyridin-3-yl)-1H-pyrazol-4-yl]-2-(methanesulfonyl)propanamide (2396747-83-2) + SX, N-[4-chloro-2-(pyridin-3-yl)-1,3-thiazol-5-yl]-N-ethyl-3-(methanesulfonyl)propanamide + SX, 1,4-dimethyl-2-[2-(pyridin-3-yl)-2H-indazol-5-yl]-1,2,4-triazolidine-3,5-dione (2171099-09-3) + SX, 2-isopropyl-5-[(3,4,4-trifluoro-3-buten-1-yl)sulfonyl]-1,3,4-thiadiazole (2058052-95-0) + SX, N-({2-fluoro-4-[(2S,3S)-2-hydroxy-3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl}methyl)cyclopropanecarboxamide + SX, 7-fluoro-N-[1-(methylsulfanyl)-2-methylpropan-2-yl]-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, 7-fluoro-N-[1-(methanesulfinyl)-2-methylpropan-2-yl]-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, 7-fluoro-N-[1-(methanesulfonyl)-2-methylpropan-2-yl]-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, N-[1-(difluoromethyl)cyclopropyl]-2-(pyridin-3-yl)-2H-indazole-4-carboxamide + SX, 2,9-dihydro-9-(methoxymethyl)-2-(pyridin-3-yl)-10H-pyrazolo[3,4-f]pyrido[2,3-b][1,4]oxazepin-10-one (2607927-97-7) + SX, 4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide + SX, 4-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide + SX, 4-[(5R)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(4R)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide + SX, 4-[(5R)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(4S)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide + SX, 4-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-[(4S)-2-ethyl-3-oxo-1,2-oxazolidin-4-yl]-2-methylbenzamide + SX, (S)-2-chloro-N-(3-ethylpentan-2-yl)furan-3-carboxamide + SX。,
[0036] Combination of this component of group (b) and this compound: acibenzolar-S-methyl + SX, aldimorph + SX, ametoctradin + SX, aminopyrifen + SX, amisulbrom + SX, anilazine + SX, azaconazole + SX, azoxystrobin + SX, basic copper sulfate + SX, benalaxyl + SX, benalaxyl-M + SX, benodanil + SX, benomyl + SX, benthiavalicarb + SX, benthiavalicarb-isopropyl + SX, benzovindiflupyr + SX, bifemetstrobin + SX, binapacryl + SX, biphenyl + SX, bitertanol + SX, bixafen + SX, blasticidin-S + SX, Bordeaux mixture + SX, boscalid + SX, bromothalonil + SX, bromuconazole + SX, bupirimate + SX, captafol + SX, captan + SX, carbendazim + SX, carboxin + SX, carpropamid + SX, chinomethionat + SX, chloroinconazide + SX, chloroneb + SX,Chlorothalonil + SX, Chlozolinate + SX, Copper(II) acetate + SX, Copper(II) hydroxide + SX, Copper oxychloride + SX, Copper(II) sulfate + SX, Coumoxystrobin + SX, Cyazofamid + SX, Cyflufenamid + SX, Cymoxanil + SX, Cyproconazole + SX, Cyprodinil + SX, Dichlobentiazox + SX, Dichlofluanid + SX, Diclocymet + SX, Diclomezine + SX, Dicloran + SX, Diethofencarb + SX, Difenoconazole + SX, Diflumetorim + SX, Dimethachlone + SX, Dimethirimol + SX, Dimethomorph + SX, Dimoxystrobin + SX, Diniconazole + SX, Diniconazole-M + SX, Dinocap + SX, Dipotassium hydrogenphosphite + SX, Dipymetitrone + SX, Dithianon + SX, Dodecylbenzenesulphonic acid bisethylenediamine copper(II) salt + SX,Dodemorph + SX, Dodine + SX, Edifenphos + SX, Enoxastrobin + SX, Epoxiconazole + SX, Etaconazole + SX, Ethaboxam + SX, Ethirimol + SX, Etridiazole + SX, Famoxadone + SX, Fenamidone + SX, Fenaminstrobin + SX, Fenarimol + SX, Fenbuconazole + SX, Feneptamidoquin + SX, Fenfuram + SX, Fenhexamid + SX, Fenopyramid + SX, Fenoxanil + SX, Fenpiclonil + SX, Fenpicoxamid + SX, Fenpropidin + SX, Fenpropimorph + SX, Fenpyrazamine + SX, Triphenyltin acetate + SX, Triphenyltin chloride + SX, Triphenyltin hydroxide + SX, Ferbam + SX, Ferimzone + SX, Florylpicoxamid + SX, Fluazinam + SX, Flubeneteram + SX, Fludioxonil + SX, Flufenoxadiazam + SX, Flufenoxystrobin + SX,Fluindapyr + SX, Flumetylsulforim + SX, Flumorph + SX, Fluopicolide + SX, Fluopyram + SX, Fluopimomide + SX, Fluoroimide + SX, Fluoxapiprolin + SX, Fluoxastrobin + SX, Fluoxytioconazole + SX, Fluquinconazole + SX, Fluquinometoate + SX, Flusilazole + SX, Flusulfamide + SX, Flutianil + SX, Flutolanil + SX, Flutriafol + SX, Fluxapyroxad + SX, Folpet + SX, Fosetyl + SX, Fosetyl-aluminium + SX, Fuberidazole + SX, Furalaxyl + SX, Furametpyr + SX, Galquin + SX, Guazatine + SX, Hexaconazole + SX, Hymexazole + SX, Imazalil + SX, Imibenconazole + SX, Iminoctadine + SX, Iminoctadine triacetate + SX, Iminoctadine trialbesilate + SX, Inpyrfluxam + SX, Iodocarb + SX,Ipconazole + SX, Ipflufenoquin + SX, Iprobenfos + SX, Iprodione + SX, Iprovalicarb + SX, Isofetamid + SX, Isoflucypram + SX, Isoprothiolane + SX, Isopyrazam + SX, Isotianil + SX, Kresoxim-methyl + SX, Mancozeb + SX, Mandestrobin + SX, Mandipropamid + SX, Maneb + SX, Mefentrifluconazole + SX, Mepanipyrim + SX, Mepronil + SX, Meptyldinocap + SX, Metalaxyl + SX, Metalaxyl-M + SX, Metarylpicoxamid + SX, Metconazole + SX, Methasulfocarb + SX, Metiram + SX, Metominostrobin + SX, Metrafenone + SX, Methyltetraprole + SX, Mineral oils + SX, Myclobutanil + SX, Naftifine + SX, Nuarimol + SX, Octhilinone + SX, Ofurace + SX, Orysastrobin + SX,Oxadixyl + SX, Oxathiapiprolin + SX, Oxine - copper + SX, Oxolinic acid + SX, Oxpoconazole + SX, Oxpoconazole fumarate + SX, Oxycarboxin + SX, Oxytetracycline + SX, Pefurazoate + SX, Penconazole + SX, Pencycuron + SX, Penflufen + SX, Penthiopyrad + SX, Phenamacril + SX, Phosphorous acid + SX, Phthalide + SX, Picarbutrazox + SX, Picoxystrobin + SX, Piperalin + SX, Potassium hydrogencarbonate + SX, Potassium dihydrogenphosphite + SX, Probenazole + SX, Prochloraz + SX, Procymidone + SX, Propamidine + SX, Propamocarb + SX, Propiconazole + SX, Propineb + SX, Proquinazid + SX, Prothiocarb + SX, Prothioconazole + SX, Pydiflumetofen + SX, Pyraclostrobin + SX,Pyrametostrobin + SX, Pyraoxystrobin + SX, Pyrapropoyne + SX, Pyraziflumid + SX, Pyrazophos + SX, Pyribencarb + SX, Pyributicarb + SX, Pyridachlometyl + SX, Pyrifenox + SX, Pyrimethanil + SX, Pyrimorph + SX, Pyriofenone + SX, Pyrisoxazole + SX, Pyroquilon + SX, Quinconazole + SX, Quinofumelin + SX, Quinoxyfen + SX, Quintozene + SX, Saccharin + SX, Saccharin sodium + SX, Saccharin potassium + SX, Saccharin calcium + SX, Saccharin ammonium + SX, Saccharin salt + SX, Seboctylamine + SX, Sedaxane + SX, Silthiofam + SX, Simeconazole + SX, Sodium carbonate peroxhydrate + SX, Sodium hydrogencarbonate + SX, Spiroxamine + SX, Sulfur + SX, Tebuconazole + SX, Tebufloquin + SX, Teclofthalam + SX, Tecnazene + SX, Terbinafine + SX, Tetraconazole + SX, Thiabendazole + SX,Thifluzamide + SX, Thiophanate + SX, Thiophanate-methyl + SX, Thiram + SX, Tiadinil + SX, Tolclofos-methyl + SX, Tolfenpyrad + SX, Tolprocarb + SX, Tolylfluanid + SX, Triadimefon + SX, Triadimenol + SX, Triazoxide + SX, Triclopyricarb + SX, Tricyclazole + SX, Tridemorph + SX, Trifloxystrobin + SX, Triflumizole + SX, Triforine + SX, Triticonazole + SX, Validamycin + SX, Valifenalate + SX, Vinclozolin + SX, Zinc thiazole + SX, Zineb + SX, Ziram + SX, Zoxamide + SX, 3-(Difluoromethyl)-N-methoxy-1-methyl-N-[(1R)-1-methyl-2-(2,4,6-trichlorophenyl)ethyl]-1H-pyrazole-4-carboxamide (1639015-48-7) + SX, 3-(Difluoromethyl)-N-methoxy-1-methyl-N-[(1S)-1-methyl-2-(2,4,6-trichlorophenyl)ethyl]-1H-pyrazole-4-carboxamide (1639015-49-8) + SX, 3-(Difluoromethyl)-1-methyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide (141573-94-6) + SX, 3-(Difluoromethyl)-N-[(3R)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide (1513466-73-3) + SX, N'-[4-({3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazol-5-yl}oxy)-2,5-dimethylphenyl]-N-ethyl-N-methylmethanimidamide (1202781-91-6) + SX, N'-{4-[(4,5-dichlorothiazol-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylmethanimidamide (929908-57-6) + SX, N'-(2,5-dimethyl-4-phenoxyphenyl)-N-ethyl-N-methylmethanimidamide (1052688-31-9) + SX, N'-[5-chloro-4-(2-fluorophenoxy)-2-methylphenyl]-N-ethyl-N-methylmethanimidamide (2055589-28-9) + SX,N'-[2-chloro-4-(2-fluorophenoxy)-5-methylphenyl]-N-ethyl-N-methylmethanimidamide (2055756-21-1) + SX, N'-(2-chloro-4-phenoxy-5-methylphenyl)-N-ethyl-N-methylmethanimidamide (2062599-39-5) + SX, N'-[4-(1-hydroxy-1-phenyl-2,2,2-trifluoroethyl)-2-methyl-5-methoxyphenyl]-N-isopropyl-N-methylmethanimidamide (2101814-55-3) + SX, N'-[5-bromo-6-(1-methyl-2-propoxyethoxy)-2-methylpyridin-3-yl]-N-ethyl-N-methylmethanimidamide (1817828-69-5) + SX, [4-(difluoromethoxy)phenyl]methyl 4-[(N-ethyl-N-methylamino)methylidene]amino-2,5-dimethylbenzoate + SX, 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazol-5-amine (1362477-26-6) + SX, 2-[6-(3-fluoro-4-methoxyphenyl)-5-methylpyridin-2-yl]quinazoline (1257056-97-5) + SX, ethyl (2Z)-3-amino-2-cyano-3-phenylacrylate (39491-78-6) + SX, N-[(2-chlorothiazol-5-yl)methyl]-N-ethyl-6-methoxy-3-nitropyridin-2-amine (1446247-98-8) + SX, α-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl]-3-pyridinemethanol (1229605-96-2) + SX, (αS)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl]-3-pyridinemethanol (1229606-46-5) + SX, (αR)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl]-3-pyridinemethanol (1229606-02-3) + SX, 5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1394057-11-4) + SX, (1R, 2S, 5S)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801930-06-2) + SX, (1S, 2R, 5R)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol ( 1801930-07-3) + SX, (1R,2R,5R)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801919-53-8) + SX, (1S,2S,5S)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801919-54-9) + SX, (1R,2R,5S)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801919-55-0) + SX, (1S,2S,5R)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801919-56-1) + SX, (1R,2S,5R)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801919-57-2) + SX, (1S,2R,5S)-5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801919-58-3) + SX, methyl 3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (1791398-02-1) + SX, methyl (1R,2S,3S)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2080743-90-2) + SX, methyl (1S,2R,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2080743-91-3) + SX, methyl (1R,2R,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2080743-92-4) + SX,methyl (1S,2S,3S)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2080743-93-5) + SX, methyl (1R,2R,3S)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2080743-94-6) + SX, methyl (1S,2S,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2080743-95-7) + SX, methyl (1R,2S,3R)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2081061-22-3) + SX, methyl (1S,2R,3S)-3-[(4-chlorophenyl)methyl]-2-hydroxy-1-methyl-2-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1-carboxylate (2081061-23-4) + SX, 2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1394057-13-6) + SX, (1R,2S,5S)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801930-08-4) + SX, (1S,2R,(5R)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1801930-09-5) + SX, (1R,2R,3R)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1638898-08-4) + SX, (1S,2S,3S)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1638898-10-8) + SX, (1R,2R,3S)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1638898-13-1) + SX, (1S,2S,5R)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1638898-16-4) + SX, (1R,2S,5R)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1638898-20-0) + SX, (1S,2R,5S)-2-(chloromethyl)-5-(4-fluorobenzyl)-2-methyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol (1638898-24-4) + SX, 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-[1-(4-bromo-2,6-difluorophenoxy)cyclopropyl]ethanol (2019215-86-0) + SX, 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-[1-(4-chloro-2,6-difluorophenoxy)cyclopropyl]ethanol (2019215-84-8) + SX, 1-[2-(1-chlorocyclopropyl)-3-(2-fluorophenyl)-2-hydroxypropyl]-1H-imidazole-5-carbonitrile (2018316-13-5) + SX, 1-[2-(1-chlorocyclopropyl)-3-(2,3-difluorophenyl)-2-hydroxypropyl]-1H-imidazole-5-carbonitrile (2018317-25-2) + SX, 2-[6-(4-bromophenoxy)-2-(trifluoromethyl)pyridin-3-yl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol (2082661-43-4) + SX, 2-[6-(4-chlorophenoxy)-2-(trifluoromethyl)pyridin-3-yl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol (2082660-27-1) + SX, methyl ({2-methyl-5-[1-(4-methoxy-2-methylphenyl)-1H-pyrazol-3-yl]phenyl}methyl)carbamate (1605879-98-8) + SX, 2-(difluoromethyl)-N-[1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1616239-21-4) + SX, 2-(difluoromethyl)-N-[(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1616239-33-8) + SX, 2-(difluoromethyl)-N-[3-ethyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1847460-02-9) + SX, 2-(difluoromethyl)-N-[(3R)-3-ethyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1952305-97-3) + SX, 2-(difluoromethyl)-N-[3-propyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1847460-05-2) + SX, 2-(difluoromethyl)-N-[(3R)-3-propyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl]pyridine-3-carboxamide (1952306-00-1) + SX, (2E,3Z)-5-{[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide (1445331-27-0) + SX, (2E,3Z)-5-{[1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpent-3-enamide (1445331-54-3) + SX, 5-chloro-4-({2-[6-(4-chlorophenoxy)pyridin-3-yl]ethyl}amino)-6-methylpyrimidine (1605340-92-8) + SX, N-(1-benzyl-1,3-dimethylbutyl)-8-fluoroquinoline-3-carboxamide (2132414-04-9) + SX, N-[(1S)-1-benzyl-1,3-dimethylbutyl]-8-fluoroquinoline-3-carboxamide + SX, N-[(1R)-1-benzyl-1,3-dimethylbutyl]-8-fluoroquinoline-3-carboxamide (2132414-06-1) + SX, 4,4-dimethyl-2-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)isoxazolidin-3-one (2098918-25-1) + SX, 5,5-dimethyl-2-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)isoxazolidin-3-one (2098918-26-2) + SX, N-ethyl-2-methyl-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)propanamide + SX, N,2-dimethoxy-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)propanamide + SX, N-methoxy-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)cyclopropanecarboxamide + SX, N-methoxy-N'-methyl-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)urea + SX, N'-ethyl-N-methoxy-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)urea + SX, N,N'-dimethoxy-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)urea + SX, N-acetyl-2-(ethanesulfonyl)-N-[2-(methoxycarbonyl)-4-(trifluoromethoxy)phenyl]-4-(trifluoromethyl)benzamide (2043675-28-9) + SX,3-(4-bromo-7-fluoroindol-1-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(7-bromoindol-1-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(7-bromo-4-fluoroindol-1-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(3,5-dichloropyridin-2-yl)butan-2-yl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, 3-(3,5-dichloropyridin-2-yl)butan-2-yl N-{[3-(acetoxymethoxy)-4-methoxypyridin-2-yl]carbonyl}-L-alaninate + SX, (1S)-1-[1-(naphthalen-1-yl)cyclopropyl]ethyl N-[(3-hydroxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, (1S)-1-[1-(naphthalen-1-yl)cyclopropyl]ethyl N-[(3-acetoxy-4-methoxypyridin-2-yl)carbonyl]-L-alaninate + SX, (1S)-1-[1-(naphthalen-1-yl)cyclopropyl]ethyl N-{[3-(acetoxymethoxy)-4-methoxypyridin-2-yl]carbonyl}-L-alaninate + SX, N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)cyclopropanecarboxamide + SX, N-allyl-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)acetamide + SX, N-allyl-N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)propanamide + SX, N-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)propanamide + SX,3,3,3-trifluoro-N-({2-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)propanamide + SX, 3,3,3-trifluoro-N-({3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)propanamide + SX, 3,3,3-trifluoro-N-({2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)propanamide + SX, N-({2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)butanamide + SX, N-methoxy-N-methyl-N'-({ 4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)urea + SX, N,N-diethyl-N'-({ 4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)urea + SX, N-methyl-N'-({ 4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)urea + SX, 1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)pyrrolidin-2-one + SX, 1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)piperidin-2-one + SX, 4-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)morpholin-3-one + SX, 2-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)isoxazolidin-3-one + SX, 3,3-dimethyl-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)piperidin-2-one + SX, 2-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)-1,2-oxazinan-3-one + SX, 1-({3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)azepan-2-one + SX, 4,4-dimethyl-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)pyrrolidin-2-one + SX, 5-methyl-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)pyrrolidin-2-one + SX, ethyl 1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)-1H-pyrazole-4-carboxylate + SX, N-methyl-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)-1H-pyrazole-4-carboxamide + SX, N-propyl-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)-1H-pyrazole-4-carboxamide + SX, N-methoxy-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)-1H-pyrazole-4-carboxamide + SX, N-methoxy-N-methyl-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)-1H-pyrazole-4-carboxamide + SX, N,N-dimethyl-1-({4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}methyl)-1H-1,2,4-triazol-3-amine + SX, ethyl 1-[(4-{[2-(trifluoromethyl)-1,3-dioxolan-2-yl]methoxy}phenyl)methyl]-1H-pyrazole-4-carboxylate + SX, ethyl 1-[(4-{[(1Z)-2-ethoxy-3,3,3-trifluoro-1-propen-1-yl]oxy}phenyl)methyl]-1H-pyrazole-4-carboxylate + SX, 6-chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N-[2-(2,4-dimethylphenyl)-2,2-difluoroethyl]-5-methylpyridazine-4-carboxamide + SX, 6-chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N-[2-(3,4-dimethylphenyl)-2,2-difluoroethyl]-5-methylpyridazine-4-carboxamide + SX, 6-chloro-N-[2-(2-chloro-4-methylphenyl)-2,2-difluoroethyl]-3-(3-cyclopropyl-2-fluorophenoxy)-5-methylpyridazine-4-carboxamide + SX, 2-[cyano(2,6-difluoropyridin-4-yl)amino]-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 2-[cyano(2,6-difluoropyridin-4-yl)amino]-N-(spiro[3.4]octan-1-yl)-5-methylthiazole-4-carboxamide + SX, 2-[cyano(2,6-(difluoropyridin-4-yl)amino]-N-hexyl-5-methylthiazole-4-carboxamide + SX, 2-[acetyl(2,6-difluoropyridin-4-yl)amino]-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 2-[(2-methoxyacetyl)(2,6-difluoropyridin-4-yl)amino]-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 2-[(2-methylpropanoyl)(2,6-difluoropyridin-4-yl)amino]-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 2-[(2,6-difluoropyridin-4-yl)amino]-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 2-{[(oxetan-3-yl)carbonyl](2,6-difluoropyridin-4-yl)amino}-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 2-{[(oxolan-3-yl)carbonyl](2,6-difluoropyridin-4-yl)amino}-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 2-{[(oxan-4-yl)carbonyl](2,6-difluoropyridin-4-yl)amino}-N-(2,2-dimethylcyclobutyl)-5-methylthiazole-4-carboxamide + SX, 5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-N-[1-(2-fluorophenyl)ethyl]pyrimidin-2-amine + SX,5-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-N-[1-(2,6-difluorophenyl)ethyl]pyrimidin-2-amine + SX, 5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-N-[1-(3,5-difluorophenyl)ethyl]pyrimidin-2-amine + SX, 5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-N-[1-(6-chloropyridin-3-yl)ethyl]pyrimidin-2-amine + SX, 5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-N-[1-(2-fluorophenyl)cyclopropyl]pyrimidin-2-amine + SX, 5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-N-[1-(2,6-difluorophenyl)cyclopropyl]pyrimidin-2-amine + SX, 5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-N-[1-(2-fluoro-3-methoxyphenyl)cyclopropyl]pyrimidin-2-amine + SX, 5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-{[1-(2,6-difluorophenyl)cyclopropyl]oxy}pyrimidine + SX, 3-[3-(3-cyclopropyl-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-[(2,4-dimethylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine + SX, (5S)-3-[3-(3-cyclopropyl-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-[(2,4-dimethylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine + SX,3-[3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-[(4-bromo-2-methylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine + SX, 3-[3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-[(2-chloro-4-methylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine + SX, (5S)-3-[3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-[(2-chloro-4-methylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine + SX, (5R)-3-[3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl]-5-[(2-chloro-4-methylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine + SX, N-((2S)-1-{3-[2-(5-fluoro-2-methoxyphenyl)-2-hydroxyethyl]-5-[(E)-1-(isopropoxyimino)ethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}-3-methylbutan-2-yl)-2-methylpropanamide + SX, N-((2S)-1-{3-[2-(5-fluoro-2-methoxyphenyl)-2-hydroxyethyl]-5-[(E)-1-(isopropoxyimino)ethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}-3-methylbutan-2-yl)-2,2-dimethylpropanamide + SX, N-((2S)-1-{3-[2-(5-fluoro-2-methoxyphenyl)-2-hydroxyethyl]-5-[(E)-1-(isopropoxyimino)ethyl]-2,6-dioxo-3,N-((2S)-1-{3-[2-(2-methoxyphenyl)-2-hydroxyethyl]-5-[(E)-1-(isopropoxyimino)ethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}propan-2-yl)-2-methylpropanamide + SX, N-((2S)-1-{3-[2-(5-fluoro-2-methoxyphenyl)-2-(2-cyanoethoxy)ethyl]-5-[1-(isopropoxyimino)ethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}propan-2-yl)-2-methylpropanamide + SX, methyl ({5-[1-(2,6-difluoro-4-isopropylphenyl)-1H-pyrazol-3-yl]-2-methylphenyl}methyl)carbamate + SX, methyl ({5-[1-(2,6-difluoro-4-cyclopropylphenyl)-1H-pyrazol-3-yl]-2-methylphenyl}methyl)carbamate + SX, methyl ({5-[1-(2,6-difluoro-4-methoxyphenyl)-1H-pyrazol-3-yl]-2-methylphenyl}methyl)carbamate + SX, methyl (Z)-2-(5-cyclopentyl-2-methylphenoxy)-3-methoxyprop-2-enoate + SX, methyl (Z)-2-(5-cyclohexyl-2-methylphenoxy)-3-methoxyprop-2-enoate + SX, methyl (Z)-2-[(3-isopropyl-1H-pyrazol-1-yl)-2-methylphenoxy]-3-methoxyprop-2-enoate + SX, 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline + SX, 1-(4,5-dimethyl-1H-benzimidazol-1-yl)-4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinoline + SX, 1-(pyrazolo[1,5-a]pyridin-3-yl)-4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline + SX, 1-(6,7-dimethylpyrazolo[1,5-a]pyridin-3-yl)-6-fluoro-3,3-dimethylisoquinolin-4(3H)-one + SX, rel-N-[(1R,2R)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)pyridine-3-carboxamide + SX, N-[(1S,2S)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)pyridine-3-carboxamide + SX, N-[(1R,2R)-2-(2,4-dichlorophenyl)cyclobutyl]-2-(trifluoromethyl)pyridine-3-carboxamide + SX, N-[2-(pyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-difluorophenyl)isoxazole-3-carboxamide + SX, N-[2-(6-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-difluorophenyl)isoxazole-3-carboxamide + SX, N-[2-(6-cyanopyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-difluorophenyl)isoxazole-3-carboxamide + SX, N-[(2S)-2-(6-chloro-4-methoxypyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,[[]]END]]4-difluorophenyl)isoxazole-3-carboxamide + SX, N-[(2R)-2-(6-chloro-4-methoxypyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-difluorophenyl)isoxazole-3-carboxamide + SX, N-(2-{6-[(1E)-(methoxyimino)ethyl]pyridin-2-yl}-2-(1-methylpyrazol-4-yl)propyl)-5-(2,4-difluorophenyl)isoxazole-3-carboxamide + SX, N-[2-(5-methylpyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-difluorophenyl)isoxazole-3-carboxamide + SX, N-[2-(6-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-dichlorophenyl)isoxazole-3-carboxamide + SX, methyl 6-(2-{[5-(2,4-difluorophenyl)isoxazole-3-carbonyl]amino}-1-methyl-1-(1-methylpyrazol-4-yl)ethyl)pyridine-3-carboxylate + SX, N-[2-(6-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(3,5-difluoropyridin-2-yl)isoxazole-3-carboxamide + SX, N-[2-(6-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-3-(2,4-difluorophenyl)-1,2,4-oxadiazole-5-carboxamide + SX, N-[2-(6-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-difluorophenyl)-1,3,4-Thiadiazole-2-carboxamide + SX, N-[2-(5-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,4-difluorophenyl)-1,3,4-thiadiazole-2-carboxamide + SX, N-[2-(6-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(3,5-difluoropyridin-2-yl)-1,3,4-thiadiazole-2-carboxamide + SX, N-[2-(6-cyanopyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(3,5-difluoropyridin-2-yl)-1,3,4-thiadiazole-2-carboxamide + SX, N-[2-(6-chloropyridin-2-yl)-2-(1-methylpyrazol-4-yl)propyl]-5-(2,6-difluoropyridin-3-yl)-1,3,4-thiadiazole-2-carboxamide + SX.,
[0037] Combination of this component of group (c) and this compound: 1-methylcyclopropene + SX, 1,3-diphenylurea + SX, 1,3,5-triazinane-2,4,6-trithione + SX, 2,3,5-triiodobenzoic acid + SX, IAA ((1H-indol-3-yl)acetic acid) + SX, IBA (4-(1H-indol-3-yl)butyric acid) + SX, MCPA (2-(4-chloro-2-methylphenoxy)acetic acid) + SX, MCPB (4-(4-chloro-2-methylphenoxy)butyric acid) + SX, 4-CPA (4-chlorophenoxyacetic acid) + SX, 5-aminolevulinic acid hydrochloride + SX, 6-benzylaminopurine + SX, abscisic acid + SX, AVG (aminoethoxyvinylglycine) + SX, anisiflupurin + SX, ancymidol + SX, butralin + SX, calcium carbonate + SX, calcium chloride + SX, calcium formate + SX, calcium peroxide + SX, calcium polysulfide + SX, calcium sulfate + SX, chlormequat-chloride + SX, chlorpropham + SX, choline chloride + SX, cloprop + SX, cyanamide + SX, cyclanilide + SX, cyprosulfamide + SX, daminozide + SX, decan-1-ol + SX,Dichlorprop + SX, Dikegulac + SX, Dimethipin + SX, Diquat + SX, Ethephon + SX, Ethychlozate + SX, Flumetralin + SX, Flurprimidol + SX, Forchlorfenuron + SX, Formononetin + SX, Gibberellin A + SX, Gibberellin A3 + SX, Inabenfide + SX, Kinetin + SX, Lipochitooligosaccharide MOR116 + SX, Lipochitooligosaccharide SP104 + SX, Maleic hydrazide + SX, Mefluidide + SX, Mepiquat-chloride + SX, Methyl-alpha-D-mannopyranoside + SX, Oxidized glutathione + SX, Paclobutrazol + SX, Pendimethalin + SX, Prohexadione-calcium + SX, Prohydrojasmon + SX, Pyraflufen-ethyl + SX, Pyroglutamic acid + SX, Sintofen + SX, Sodium 1-naphthaleneacetate + SX, Sodium cyanate + SX, Thidiazuron + SX, Titanium apatite + SX,Triapenthenol + SX, Tribufos + SX, Trinexapac-ethyl + SX, Uniconazole-P + SX, 2-(Naphthalen-1-yl)acetamide + SX, [4-Oxo-4-(2-phenylethyl)amino]butyric acid + SX, Methyl 5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate + SX, 3-[(6-Chloro-4-phenylquinazolin-2-yl)amino]propan-1-ol + SX, Strigolactone + SX, (1E)-1-[[1-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-5-oxo-2H-pyrrol-2-yl]oxymethylene]-3,3a,4,8b-tetrahydroindeno[2,1-b]pyrrol-2-one described in International Publication No. WO 2018 / 145979 + SX, (2R)-1-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-[(E)-(2-oxo-4,8b-dihydro-3aH-indeno[2,1-b]furan-1-ylidene)methoxy]-2H-pyrrol-5-one described in International Publication No. WO 2018 / 145979 + SX, (2S)-1-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-2-[(E)-(2-oxo-4,8b-dihydro-3aH-indeno[2,1-b]furan-1-ylidene)methoxy]-2H-pyrrol-5-one described in International Publication No. WO 2018 / 145979 + SX.,
[0038] The combination of the component of the above group (d) and the present compound: Allidochlor + SX, Benoxacor + SX, Cloquintocet + SX, Cloquintocet-mexyl + SX, Cyometrinil + SX, Cyprosulfamide + SX, Dichlormid + SX, Dicyclonone + SX, Dimepiperate + SX, Disulfoton + SX, Dymron + SX, Fenchlorazole + SX, Fenchlorazole-ethyl + SX, Fenclorim + SX, Flurazole + SX, Furilazole + SX, Fluxofenim + SX, Hexim + SX, Isoxadifen + SX, Isoxadifen-ethyl + SX, Jiecaowan + SX, Jiecaoxi + SX, Mecoprop + SX, Mefenpyr + SX, Mefenpyr-ethyl + SX, Mefenpyr-diethyl + SX, Mephenate + SX, Metcamifen + SX, Oxabetrinil + SX, 1,8-Naphthalic anhydride + SX, Octane-1,8-diamine + SX, AD-67 (4-(dichloroacetyl)-1-oxa-4-azaspiro [4.5] decane) + SX, CL-304415 (4-carboxy-3,4-dihydro-2H-1-benzopyran-4-acetic acid) + SX, CSB (1-bromo-4-[(chloromethyl)sulfonyl]benzene) + SX, DKA-24 (2,2-dichloro-N-[2-oxo-2-(2-propenylamino)ethyl]-N-(2-propenyl)acetamide) + SX, MG191 (2-(dichloromethyl)-2-methyl-1,3-dioxolane) + SX, MG-838 (2-propenyl 1-oxa-4-azaspiro[4.5]decane-4-carbodithioate) + SX, PPG-1292 (2,2-dichloro-N-(1,3-dioxan-2-ylmethyl)-N-(2-propenyl)acetamide) + SX, R-28725 (3-(dichloroacetyl)-2,2-dimethyl-1,3-oxazolidine) + SX, R-29148 (3-(dichloroacetyl)-2,2,5-trimethyl-1,3-oxazolidine) + SX, TI-35 (1-(dichloroacetyl)azepane) + SX。
[0039] Combination of this component of group (e) and this compound: 1-Dodecyl-1H-imidazole + SX, N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide + SX, Bucarpolate + SX, N,N-dibutyl-4-chlorobenzenesulfonamide + SX, Dietholate + SX, Diethylmaleate + SX, Jiajizengxiaolin + SX, Octachlorodipropyl ether + SX, Perbutin + SX, Piperonyl butoxide + SX, Piperonyl cyclonene + SX, Piprotal + SX, Propyl isome + SX, Safroxan + SX, Sesamex + SX, Sesamolin + SX, Sulfoxide + SX, Verbutin + SX, DMC (1,1-bis(4-chlorophenyl)ethanol) + SX, FDMC (1,1-bis(4-chlorophenyl)-2,2,2-trifluoroethanol) + SX, ETN (1,2-epoxy-1,2,3,4-tetrahydronaphthalene) + SX, ETP (1,1,1-trichloro-2,3-expoxypropane) + SX, PSCP (phenylsaligenin cyclic phosphate) + SX, TBPT (S,S,S-tributyl phosphorotrithioate) + SX, TPP (triphenyl phosphate) + SX。
[0040] Combination of the main component of the above group (f) and this compound: Anthraquinone + SX, Chloralose + SX, Acrep + SX, Butopyronoxyl + SX, Camphor + SX, d-Camphor + SX, Carboxide + SX, Dibutyl phthalate + SX, Deet + SX, Dimethyl carbate + SX, Dimethyl phthalate + SX, Dibutyl succinate + SX, Dibutyl adipate + SX, Ethohexadiol + SX, Hexamide + SX, Icaridin + SX, Methoquin-butyl + SX, Methylneodecanamide + SX, 2-(Octylthio)ethanol + SX, Butoxypolypropylene glycol + SX, Oxamate + SX, Quwenzhi + SX, Quyingding + SX, Zengxiaon + SX, Rebemide + SX, Copper naphthenate + SX, Zinc naphthenate + SX.
[0041] Combination of the main component of the above group (g) and this compound: Bis(tributyltin) oxide + SX, Allicin + SX, Bromoacetamide + SX, Calcium arsenate + SX, Cloethocarb + SX, Copper sulfate + SX, Fentin + SX, Ferric phosphate + SX, Metaldehyde + SX, Niclosamide + SX, Paris green + SX, Pentachlorophenol + SX, Sodium ferric EDTA + SX, Sodium pentachlorophenoxide + SX, Tazimcarb + SX, Tralopyril + SX, Tributyltin oxide + SX, Trifenmorph + SX.
[0042] Combination of this component of the above group (h) and this compound: (4Z,7Z)-deca-4,7-dien-1-yl acetate + SX, (2E)-dec-2-en-1-ol + SX, (4Z)-dec-4-en-1-yl acetate + SX, (5Z)-dec-5-en-1-ol + SX, (5Z)-dec-5-en-1-yl acetate + SX, (8Z)-dec-8-en-1-ol + SX, (7Z,13Z,16Z,19Z)-docosa-7,13,16,19-tetraen-1-ly isobutylate + SX, (7Z)-dodec-7-en-1-yl acetate + SX, (8Z)-dodec-8-en-1-ol + SX, (8E)-dodec-8-en-1-yl acetate + SX, (8Z)-dodec-8-en-1-yl acetate + SX, (9E)-dodec-9-en-1-yl acetate + SX, (9Z)-dodec-9-en-1-yl acetate + SX, (3Z)-dodec-3-en-1-yl (2E)-but-2-enoate + SX, (7E,9E)-dodeca-7,9-dien-1-yl acetate + SX, (7E,9Z)-dodeca-7,9-dien-1-yl acetate + SX, (7Z,9E)-dodeca-7,9-dien-1-yl acetate + SX, (8E,10E)-dodeca-8,10-dien-1-ol + SX, (8E,10E)-dodeca-8,10-dien-1-yl acetate + SX, (6Z)-henicos-6-en-1-one + SX, (9Z)-hexadec-9-enal + SX, (9Z)-hexadec-9-en-1-yl acetate + SX, (10Z)-hexadec-10-en-1-yl acetate + SX, (11Z)-hexadec-11-enal + SX, (11Z)-hexadec-11-en-1-ol + SX, (11Z)-hexadec-11-en-1-yl acetate + SX, (13Z)-hexadec-13-en-11-yn-1-yl acetate + SX, (7Z,11Z)-hexadeca-7,11-dienal + SX, (7E,11E)-hexadeca-7,11-dien-1-yl acetate + SX, (7E,11Z)-hexadeca-7,11-dien-1-yl acetate + SX, (7Z,11E)-hexadeca-7,11-dien-1-yl acetate + SX, (7Z,11Z)-hexadeca-7,11-dien-1-yl acetate + SX, (10E,12E)-hexadeca-10,12-dienal + SX, (11Z,13Z)-hexadeca-11,13-dienal + SX, (7Z,11Z,13Z)-hexadeca-7,11,13-trienal + SX, (7Z,11Z,13E)-hexadeca-7,11,13-trienal + SX, (13Z)-icos-13-en-10-one + SX, (2E)-6-methylhept-2-en-4-ol + SX, (11Z)-octadec-11-en-1-ol + SX, (11Z)-octadec-11-enal + SX, (13Z)-octadec-13-enal + SX, (2E,13Z)-octadeca-2,13-dien-1-ol + SX, (2E,13Z)-octadeca-2,13-dien-1-yl acetate + SX, (2Z,13Z)-octadeca-2,13-dien-1-yl acetate + SX, (3E,13Z)-octadeca-3,13-dien-1-ol + SX, (3E,13Z)-octadeca-3,13-dien-1-yl acetate + SX, (3Z,13Z)-octadeca-3,13-dien-1-ol + SX, (3Z,13Z)-octadeca-3,13-dien-1-yl acetate + SX, (7Z)-tetradec-7-enal + SX, (7Z)-tetradec-7-en-2-one + SX, (9Z)-tetradec-9-en-1-ol + SX, (9Z)-tetradec-9-en-1-yl acetate + SX, (11Z)-tetradec-11-enal + SX,(11E)-tetradec-11-en-1-yl acetate + SX, (11Z)-tetradec-11-en-1-yl acetate + SX, (3E,8Z)-tetradeca-3,8-dien-1-yl acetate + SX, (4E,10Z)-tetradeca-4,10-dien-1-yl acetate + SX, (8E,10Z)-tetradeca-8,10-dienal + SX, (9E,11E)-tetradeca-9,11-dien-1-yl acetate + SX, (9Z,11E)-tetradeca-9,11-dien-1-yl acetate + SX, (9Z,12E)-tetradeca-9,12-dien-1-yl acetate + SX, (3E,8Z,11Z)-tetradeca-3,8,11-trien-1-yl acetate + SX, (9E)-tricos-9-ene + SX, (4E)-tridec-4-en-1-yl acetate + SX, (4Z)-tridec-4-en-1-yl acetate + SX, allyl isothiocyanate + SX, 4-allylanisole + SX, 3-carene + SX, (5R)-5-[(1Z)-dec-1-en-1-yl]dihydro-2(3H)-furanone + SX, (5R)-5-[(1Z)-dec-1-en-1-yl]dihydro-2(3H)-furanone + eugenol + 2-phenylethyl propionate + SX, (Z)-2-(3,3-dimethylcyclohexylidene)ethanol + SX, (4R,8R)-4,8-dimethyldecanal + SX, (4R,8S)-4,8-dimethyldecanal + SX, 2,4-dimethyl-5-ethyl-6,8-dioxabicyclo[3,2,1]octane + SX, 1,7-dioxaspiro[5,5]undecane + SX, dodecan-1-ol + SX, dodecyl acetate + SX, ethyl (2E,4Z)-deca-2,4-dienoate + SX, ethyl 4-methyloctanoate + SX, (2R,5R)-ethyl-1,6-dioxaspiro[4,4]nonane + SX, (2R,5S)-ethyl-1,6-dioxaspiro[4,4]nonane + SX, (E)-β-farnesene + SX, farnesyl alcohol + SX, ferrugineol + SX, geranyl hexanoate + SX, (E)-2-hexenyl butyrate + SX, (E)-2-hexenyl butyrate + hexyl butyrate + (E)-4-oxo-2-hexenal + SX, hexyl butyrate + SX, jasmone + SX, 3-ketopetromyzonol-24-sulfate ammonium salt + SX, methyl 2,6,10-trimethyldodecanoate + SX, methyl (2E,4E)-hepta-2,4-dienoate + SX, 2-methylbut-3-en-1-ol + SX, 2-(1-methyl-2-prop-1-en-2-ylcyclobutyl)ethanol + SX, 3-methylcyclohex-2-en-1-one + SX, (-)-4-methylheptan-3-ol + SX, 4-methylnonan-5-ol + SX, 4-methylnonan-5-one + SX, 14-methyloctadec-1-ene + SX, nepetalactone + SX, ocimene + SX, 1,2-octanediol + SX, oct-1-en-3-ol + SX, (R)-oct-1-en-3-ol + SX, olean + SX, 4-(3-oxobutyl)phenyl acetate + SX, (E)-4-oxo-2-hexenal + SX, pentacosane + SX, penta-termanone + SX, phenylacetaldehyde + SX, putrescine + SX, tetradecan-1-ol + SX,tetradecyl acetate + SX, tricosane + SX, tridecan-2-one + SX, 1,2,4-trimethoxybenzene + SX, trimethylamine + SX, trimethylamine hydrochloride + SX, 2-(undecyloxy)ethanol + SX, querciverol + SX, α-terpinene + SX, α-terpineol + SX, α-terpinoline + SX, animal tissue hydrolysate + SX, beet molasses-urea hydrolysate + SX, camphene + SX, capilure + SX, ceralure + SX, chalcogran + SX, codlelure + SX, codlemone + SX, copaene + SX, cosmolure + SX, cucujolide VIII + SX, cuelure + SX, cyclotene + SX, disparlure + SX, dominicalure + SX, endobrevicomin + SX, eugenol + SX, exitlure + SX, exobrevicomin + SX, farnesol + SX, ferrolure + SX, frontalin + SX, german cockroach pheromone + SX, gossyplure + SX, gossyplure HF + SX,Grandlure + SX, Grandlure I + SX, Grandlure II + SX, Grandlure III + SX, Grandlure IV + SX, Hexalure + SX, Ipsdienol + SX, Ipsenol + SX, Japonilure + SX, Lavandin oil + SX, Lineatin + SX, Litlue + SX, Looplure + SX, Medlure + SX, Megatomoic acid + SX, Methyl eugenol + SX, Multistriatin + SX, Muscalure + SX, Nerolidol + SX, Orfralure + SX, Oryctalure + SX, Ostramone + SX, Peachflure + SX, Prodenialure B + SX, Rescalure + SX, Rhyncolure + SX, Siglure + SX, Sordidin + SX, Sulcatol + SX, Trimedlure + SX, Trimedlure A + SX, Trimedlure B1 + SX, Trimedlure B2 + SX, Trimedlure C + SX, Trunc-call + SX, (E)-Verbenol + SX, (Z)-Verbenol + SX, Trans-verbenol + SX,(S)-verbenone + SX.,
[0043] Combination of the main component of the above group (i) and this compound: 2,3,6-TBA (2,3,6-trichlorobenzoic acid) + SX, 2,3,6-TBA dimethylammonium + SX, 2,3,6-TBA lithium salt + SX, 2,3,6-TBA potassium salt + SX, 2,3,6-TBA sodium salt + SX, 2,4-D + SX, 2,4-D choline salt + SX, 2,4-D biproamine + SX, 2,4-D doboxyl + SX, 2,4-D 2-ethylhexyl + SX, 2,4-D 3-butoxypropyl + SX, 2,4-D ammonium + SX, 2,4-D butotyl + SX, 2,4-D butyl + SX, 2,4-D diethylammonium + SX, 2,4-D dimethylammonium + SX, 2,4-D diolamine salt + SX, 2,4-D dodecylammonium + SX, 2,4-D ethyl + SX, 2,4-D heptylammonium + SX, 2,4-D isobutyl + SX, 2,4-D isooctyl + SX, 2,4-D isopropyl + SX, 2,4-D isopropylammonium + SX, 2,4-D lithium salt + SX, 2,4-D mepty + SX, 2,4-D methyl (2,[4-D-methyl) + SX, 2,4-D octyl + SX, 2,4-D pentyl + SX, 2,4-D propyl + SX, 2,4-D sodium salt + SX, 2,4-D tefuryl + SX, 2,4-D tetradecylammonium + SX, 2,4-D triethylammonium + SX, 2,4-D tris(2-hydroxypropyl)ammonium + SX, 2,4-D trolamine salt + SX, 2,4-DB + SX, 2,4-DB choline salt + SX, 2,4-DB biproamine + SX, 2,4-DB butyl + SX, 2,4-DB dimethylammonium + SX, 2,4-DB isooctyl + SX, 2,4-DB potassium salt + SX, 2,4-DB sodium salt + SX, acetochlor + SX, acifluorfen + SX, acifluorfen-sodium + SX, aclonifen + SX, ACN (2-amino-3-chloronaphthalene-1,4-dione) + SX, alachlor + SX, alloxydim + SX, ametryn + SX, amicarbazone + SX, amidosulfuron + SX, aminocyclopyrachlor + SX,Aminocyclopyrachlor-methyl + SX, Aminocyclopyrachlor-potassium + SX, Aminopyralid + SX, Aminopyralid choline salt + SX, Aminopyralid-potassium + SX, Aminopyralid-tripromine + SX, Amiprophos-methyl + SX, Amitrole + SX, Anilofos + SX, Asulam + SX, Atrazine + SX, Azafenidin + SX, Azimsulfuron + SX, Beflubutamid + SX, Benazolin-ethyl + SX, Bencarbazone + SX, Benfluralin + SX, Benfuresate + SX, Benquitrione + SX, Bensulfuron + SX, Bensulfuron-methyl + SX, Bensulide + SX, Bentazon + SX, Benthiocarb + SX, Benzfendizone + SX, Benzobicyclon + SX, Benzofenap + SX, Benzthiazuron + SX, Bialaphos + SX, Bicyclopyrone + SX, Bifenox + SX, Bipyrazone + SX, Bispyribac + SX,bispyribac-sodium + SX, bixlozone + SX, bromacil + SX, bromobutide + SX, bromofenoxim + SX, bromoxynil + SX, bromoxynil-octanoate + SX, butachlor + SX, butafenacil + SX, butamifos + SX, butroxydim + SX, butylate + SX, cafenstrole + SX, carbetamide + SX, carfentrazone + SX, carfentrazone-ethyl + SX, chlomethoxyfen + SX, chloramben + SX, chloridazon + SX, chlorimuron + SX, chlorimuron-ethyl + SX, chlorobromuron + SX, chlorotoluron + SX, chloroxuron + SX, chlorpropham + SX, chlorsulfuron + SX, chlorthal-dimethyl + SX, chlorthiamid + SX, cinflubrolin + SX, cinidon + SX, cinidon-ethyl + SX, cinmethylin + SX, cinosulfuron + SX, clethodim + SX, clodinafop + SX,Clodinafop-propargyl + SX, Clomazone + SX, Clomeprop + SX, Clopyralid + SX, Clopyralid choline salt + SX, Clopyralid-methyl + SX, Clopyralid-olamine + SX, Clopyralid-potassium + SX, Clopyralid-tris(2-hydroxypropyl)ammonium + SX, Cloransulam + SX, Cloransulam-methyl + SX, Cumyluron + SX, Cyanazine + SX, Cycloate + SX, Cyclopyranil + SX, Cyclopyrimorate + SX, Cyclosulfamuron + SX, Cycloxydim + SX, Cyhalofop + SX, Cyhalofop-butyl + SX, Cypyrafluone + SX, Dalapon + SX, Dazomet + SX, Desmedipham + SX, Desmetryn + SX, Di-allate + SX, Dicamba + SX, Dicamba choline salt + SX, Dicamba-biproamine + SX, Dicamba -trolamine + SX, Dicamba-diglycolamine + SX,Dicamba-dimethylammonium + SX, Dicamba-diolamine + SX, Dicamba-isopropylammonium + SX, Dicamba-methyl + SX, Dicamba-olamine + SX, Dicamba-potassium + SX, Dicamba-sodium + SX, Dichlobenil + SX, Dichlorprop choline salt + SX, Dichlorprop-biproamine + SX, Dichlorprop-2-ethylhexyl + SX, Dichlorprop-butotyl + SX, Dichlorprop-dimethylammonium + SX, Dichlorprop-ethylammonium + SX, Dichlorprop-isoctyl + SX, Dichlorprop-methyl + SX, Dichlorprop-P + SX, Dichlorprop-P choline salt + SX, Dichlorprop-P-biproamine + SX, Dichlorprop-P-etexyl + SX, Dichlorprop-P-dimethylammonium + SX, Dichlorprop-potassium + SX, Dichlorprop-sodium + SX, Diclofop + SX,Diclofop-methyl + SX, Diclosulam + SX, Difenoxuron + SX, Difenzoquat + SX, Difenzoquat metilsulfate + SX, Diflufenican + SX, Diflufenzopyr + SX, Diflufenzopyr-sodium + SX, Dimefuron + SX, Dimepiperate + SX, Dimesulfazet + SX, Dimethachlor + SX, Dimethametryn + SX, Dimethenamid + SX, Dimethenamid-P + SX, Dinitramine + SX, Dinoseb + SX, Dinoterb + SX, Dioxopyritrione + SX, Diphenamid + SX, Diquat-dibromide + SX, DSMA (Disodium methylarsonate) + SX, Dithiopyr + SX, Diuron + SX, DNOC (2-Methyl-4,6-dinitrophenol) + SX, Epyrifenacil + SX, Esprocarb + SX, Ethalfluralin + SX, Ethametsulfuron + SX, Ethametsulfuron-methyl + SX, Ethidimuron + SX, Ethofumesate + SX, Ethoxyfen-ethyl + SX, Ethoxysulfuron + SX, Etobenzanid + SX, Fenoxaprop + SX, Fenoxaprop-ethyl + SX, Fenoxaprop-P + SX,fenoxaprop-P-ethyl + SX, fenoxasulfone + SX, fenpyrazone + SX, fenquinotrione + SX, fentrazamide + SX, fenuron + SX, feproxydim + SX, flamprop-M + SX, flazasulfuron + SX, florasulam + SX, florpyrauxifen + SX, florpyrauxifen-benzyl + SX, fluazifop + SX, fluazifop-butyl + SX, fluazifop-P + SX, fluazifop-P-butyl + SX, fluazolate + SX, flucarbazone + SX, flucarbazone-sodium + SX, flucetosulfuron + SX, fluchloraminopyr + SX, fluchloraminopyr-tefuryl + SX, flufenacet + SX, flufenoximacil + SX, flufenpyr + SX, flufenpyr-ethyl + SX, flumetsulam + SX, flumetsulam + SX, flumiclorac + SX, flumiclorac-pentyl + SX, flumioxazin + SX, fluometuron + SX,fluoroglycofen-ethyl + SX, flupoxam + SX, flupropanate + SX, flupyrsulfuron + SX, flupyrsulfuron-methyl-sodium + SX, flurenol + SX, fluridone + SX, flurochloridone + SX, fluroxypyr + SX, fluroxypyr-butometyl + SX, fluroxypyr-meptyl + SX, flurtamone + SX, flusulfinam + SX, fluthiacet + SX, fluthiacet-methyl + SX, fomesafen + SX, fomesafen-sodium + SX, foramsulfuron + SX, fosamine + SX, glufosinate + SX, glufosinate-ammonium + SX, glufosinate-P + SX, glufosinate-P-ammonium + SX, glufosinate-P-sodium + SX, glyphosate + SX, glyphosate choline salt + SX, glyphosate-isopropylammonium + SX, glyphosate-biproamine + SX, glyphosate-ammonium + SX,Glyphosate-diammonium + SX, Glyphosate-potassium + SX, Glyphosate-sodium + SX, Glyphosate-trimesium + SX, Halauxifen + SX, Halauxifen-benzyl + SX, Halauxifen-methyl + SX, Halosafen + SX, Halosulfuron + SX, Halosulfuron-methyl + SX, Haloxyfop + SX, Haloxyfop-etotyl + SX, Haloxyfop-methyl + SX, Haloxyfop-P + SX, Haloxyfop-P-etotyl + SX, Haloxyfop-P-methyl + SX, Hexazinone + SX, Icafolin + SX, Icafolin-methyl + SX, Imazamethabenz + SX, Imazamethabenz-methyl + SX, Imazamox + SX, Imazamox-ammonium + SX, Imazamox-sodium + SX, Imazapic + SX, Imazapic-ammonium + SX, Imazapyr + SX, Imazapyr-ammonium + SX, Imazapyr-isopropylammonium + SX,Imazaquin + SX, Imazaquin-ammonium + SX, Imazethapyr + SX, Imazethapyr-ammonium + SX, Imazosulfuron + SX, Indanofan + SX, Indaziflam + SX, Indolauxipyr + SX, Indolauxipyr-cyanomethyl + SX, Iodosulfuron + SX, Iodosulfuron-methyl-sodium + SX, Iofensulfuron + SX, Iofensulfuron-sodium + SX, Ioxynil + SX, Ioxynil-octanoate + SX, Ipfencarbazone + SX, Iptriazopyrid + SX, Isoproturon + SX, Isouron + SX, Isoxaben + SX, Isoxachlortole + SX, Isoxafenacil + SX, Isoxaflutole + SX, Lactofen + SX, Lenacil + SX, Linuron + SX, Maleic hydrazide + SX, MCPA choline salt + SX, MCPA-biproamine + SX, MCPA-etexyl + SX, MCPA-butotyl + SX, MCPA-butyl + SX,MCPA dimethylammonium + SX, MCPA diolamine + SX, MCPA ethyl + SX, MCPA isobutyl + SX, MCPA isooctyl + SX, MCPA isopropyl + SX, MCPA methyl + SX, MCPA olamine + SX, MCPA sodium + SX, MCPA trolamine + SX, MCPB (4-(4-chloro-2-methylphenoxy)butanoic acid) + SX, MCPB choline salt + SX, MCPB biproamine + SX, MCPB ethyl + SX, MCPB methyl + SX, MCPB sodium + SX, mecoprop choline salt + SX, mecoprop-biproamine + SX, mecoprop 2-ethylhexyl + SX, mecoprop dimethylammonium + SX, mecoprop diolamine + SX, mecoprop ethadyl + SX, mecoprop isooctyl + SX, mecoprop methyl + SX, mecoprop potassium + SX, mecoprop sodium + SX, mecoprop trolamine + SX, mecoprop-P + SX,Mecoprop-P choline salt + SX, Mecoprop-P 2-ethylhexyl + SX, Mecoprop-P-dimethylammonium + SX, Mecoprop-P-isobutyl + SX, Mecoprop-P-potassium + SX, Mefenacet + SX, Mesosulfuron + SX, Mesosulfuron-methyl + SX, Mesotrione + SX, Metam + SX, Metamifop + SX, Metamitron + SX, Metazachlor + SX, Metazosulfuron + SX, Methabenzthiazuron + SX, Methiozolin + SX, Methyldymron + SX, Metobromuron + SX, Metolachlor + SX, Metoxuron + SX, Metsosulam + SX, Metproxybicyclone + SX, Metribuzin + SX, Metsulfuron + SX, Metsulfuron-methyl + SX, Molinate + SX, Monolinuron + SX, Naproanilide + SX, Napropamide + SX, Napropamide-M + SX, Naptalam + SX, Neburon + SX, Nicosulfuron + SX, Norflurazon + SX, Oleic acid + SX, Orbencarb + SX, Orthosulfamuron + SX, Oryzalin + SX, Oxadiargyl + SX, Oxadiazon + SX, Oxasulfuron + SX, Oxaziclomefone + SX, Oxyfluorfen + SX, Paraquat + SX, Paraquat-dichloride + SX, Pebulate + SX, Pelargonic acid + SX, Pendimethalin + SX, Penoxsulam + SX, Pentanochlor + SX, Pentoxazone + SX, Pethoxamid + SX, Phenisopham + SX,phenmedipham + SX, picloram, picolinafen + SX, picolinafen + SX, pinoxaden + SX, piperophos + SX, pretilachlor + SX, primisulfuron + SX, primisulfuron-methyl + SX, prodiamine + SX, profluazol + SX, profoxydim + SX, prometon + SX, prometryn + SX, propachlor + SX, propanil + SX, propaquizafop + SX, propazine + SX, propham + SX, propisochlor + SX, propoxycarbazone + SX, propoxycarbazone-sodium + SX, propyrisulfuron + SX, propyzamide + SX, prosulfocarb + SX, prosulfuron + SX, pyraclonil + SX, pyraquinate + SX, pyrasulfotole + SX, pyrazolynate + SX, pyrazosulfuron + SX, pyrazosulfuron-ethyl + SX, pyrazoxyfen + SX, pyribenzoxim + SX, pyributicarb + SX,Pyridafol + SX, Pyridate + SX, Pyriflubenzoxim + SX, Pyriftalid + SX, Pyriminobac + SX, Pyriminobac-methyl + SX, Pyrimisulfan + SX, Pyrithiobac + SX, Pyrithiobac-sodium + SX, Pyroxasulfone + SX, Pyroxsulam + SX, Quinclorac + SX, Quinmerac + SX, Quizalofop + SX, Quizalofop-ethyl + SX, Quizalofop-tefuryl + SX, Quizalofop-P + SX, Quizalofop-P-ethyl + SX, Quizalofop-P-tefuryl + SX, Rimisoxafen + SX, Rimsulfuron + SX, Saflufenacil + SX, Sethoxydim + SX, EPTC (S-ethyl N,N-dipropylcarbamothioate) + SX, Siduron + SX, Simazine + SX, Simetryn + SX, S-metolachlor + SX, MSMA (sodium hydrogen methylarsonate) + SX, Sulcotrione + SX, Sulfentrazone + SX, Sulfometuron + SX, Sulfometuron-methyl + SX,Sulfosulfuron + SX, Swep + SX, TCA (2,2,2 - trichloroacetic acid) + SX, TCA - ammonium + SX, TCA - calcium + SX, TCA - ethadyl + SX, TCA - magnesium + SX, TCA - sodium + SX, Tebutam + SX, Tebuthiuron + SX, Tefuryltrione + SX, Tembotrione + SX, Tepraloxydim + SX, Terbacil + SX, Terbumeton + SX, Terbuthylazine + SX, Terbutryn + SX, Tetflupyrolimet + SX, Thaxtomin A + SX, Thenylchlor + SX, Thiazopyr + SX, Thidiazimin + SX, Thiencarbazone + SX, Thiencarbazone - methyl + SX, Thifensulfuron + SX, Thifensulfuron - methyl + SX, Tiafenacil + SX, Tiocarbazil + SX, Tolpyralate + SX, Topramezone + SX, Tralkoxydim + SX, Triafamone + SX, Tri - allate + SX, Triasulfuron + SX, Triaziflam + SX,Tribenuron + SX, tribenuron-methyl + SX, triclopyr + SX, triclopyr-butotyl + SX, triclopyr-ethyl + SX, triclopyr-triethylammonium + SX, tridiphane + SX, trietazine + SX, trifloxysulfuron + SX, trifloxysulfuron-sodium + SX, trifludimoxazin + SX, trifluralin + SX, triflusulfuron + SX, triflusulfuron-methyl + SX, tripyrasulfone + SX, tritosulfuron + SX, vernolate + SX, 4-(4-fluorophenyl)-6-[(2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl]-2-methyl-1,2,4-triazine-3,5(2H,4H)-dione + SX, 2-chloro-N-(1-methyl-1H-tetrazol-5-yl)-3-(methylthio)-4-(trifluoromethyl)benzamide + SX, 2-methyl-N-(5-methyl-1,3,4-oxadiazol-2-yl)-3-(methanesulfonyl)-4-(trifluoromethyl)benzamide + SX, 1-{2-chloro-6-[(5-chloropyrimidin-2-yl)oxy]phenyl}-4,4,4-trifluorobutan-1-one (2052297-97-7) + SX.,
[0044] Combination of the main component of the above group (j) and this compound:
[0045] Subgroup (j-1): Combination of the main component of bacteria and this compound: Acidovorax wautersii + SX, Agrobacterium radiobacter strain K1026 + SX, Agrobacterium radiobacter strain K84 + SX, Agrobacterium vitis strain VAR03-1 + SX, Arthrobacter globiformis + SX, Arthrobacter globiformis + Erwinia gerundensis + SX, Azorhizobium spp. + SX, Azorhizobium caulinodans strain ZB-SK-5 + SX, Azospirillum amazonense + SX, Azospirillum brasilense + SX, Azospirillum brasilense strain XOH + SX, Azospirillum brasilense strain Ab-V5 + SX, Azospirillum brasilense strain Ab-V6 + SX, Azospirillum caulinodans + SX, Azospirillum halopraeferens + SX, Azospirillum irakense + SX, Azospirillum lipoferum + SX, Azotobacter + SX,Azotobacter chroococcum + SX, Azotobacter chroococcum strain H23 + SX, Azotobacter salinestris strain CECT9690 + SX, Azotobacter vinelandii strain ATCC12837 + SX, Bacillus acidocaldarius + SX, Bacillus acidoterrestris + SX, Bacillus agri + SX, Bacillus albolactis + SX, Bacillus alcalophilus + SX, Bacillus alvei + SX, Bacillus aminoglucosidicus + SX, Bacillus aminovorans + SX, Bacillus amyloliquefaciens strain PTA-4838 (Aveo (trademark) EZ Nematicide) + SX, Bacillus amyloliquefaciens strain AH2 + SX, Bacillus amyloliquefaciens strain AT79 + SX, Bacillus amyloliquefaciens strain AT332 + SX, Bacillus amyloliquefaciens strain B3 + SX,Bacillus amyloliquefaciens strain BV03 + SX, Bacillus amyloliquefaciens strain CECT7657 + SX, Bacillus amyloliquefaciens strain D203 + SX, Bacillus amyloliquefaciens strain D747 + SX, Bacillus amyloliquefaciens strain DB101 + SX, Bacillus amyloliquefaciens strain DB102 + SX, Bacillus amyloliquefaciens strain ENV503 + SX, Bacillus amyloliquefaciens strain F727 + SX, Bacillus amyloliquefaciens strain FZB24 + SX, Bacillus amyloliquefaciens strain FZB42 + SX, Bacillus amyloliquefaciens strain GB03 + SX, Bacillus amyloliquefaciens strain IN937a + SX, Bacillus amyloliquefaciens strain IT-45 + SX, Bacillus amyloliquefaciens strain MBI600 + SX,Bacillus amyloliquefaciens strain R6-CDX + SX, Bacillus amyloliquefaciens isolate strain B246 + SX, Bacillus amyloliquefaciens subsp. Plantarum strain D747 + SX, Bacillus amylolyticus + SX, Bacillus aneurinolyticus + SX, Bacillus atrophaeus + SX, Bacillus atrophaeus strain Abi05 + SX, Bacillus azotoformans + SX, Bacillus badius + SX, Bacillus cereus strain Ar56 + SX, Bacillus cereus strain B4 + SX, Bacillus cereus strain BP01 + SX, Bacillus cereus strain bromelia + SX, Bacillus cereus strain CIL + SX, Bacillus cereus CNCM strain I-1562 + SX, Bacillus cereus strain DGA34 + SX, Bacillus cereus strain N6 + SX, Bacillus cereus strain N7 + SX,Bacillus cereus strain peumo + SX, Bacillus cereus strain UW85 + SX, Bacillus chitinosporus strain AQ746 + SX, Bacillus chitinosporus strain CM-1 + SX, Bacillus circulans + SX, Bacillus coagulans strain TQ33 + SX, Bacillus fastidiosus + SX, Bacillus firmus strain GB-126 + SX, Bacillus firmus strain I-1582 + SX, Bacillus firmus strain NCIM2637 + SX, Bacillus lacticola + SX, Bacillus lactimorbus + SX, Bacillus lactis + SX, Bacillus lautus + SX, Bacillus lentimorbus + SX, Bacillus lentus + SX, Bacillus licheniformis strain copihue + SX, Bacillus licheniformis strain B000106 + SX, Bacillus licheniformis strain DSM17236 + SX,Bacillus licheniformis strain FMCH001 + SX, Bacillus licheniformis strain HB-2 + SX, Bacillus licheniformis strain SB3086 + SX, Bacillus maroccanus + SX, Bacillus medusa + SX, Bacillus megaterium strain ATCC10778 + SX, Bacillus megaterium strain NCIM2087 + SX, Bacillus megaterium strain YFM3.25 + SX, Bacillus methylotrophicus strain BAC-9912 + SX, Bacillus methylotrophicus strain C1 + SX, Bacillus methylotrophicus isolate UFPEDA20 + SX, Bacillus metiens + SX, Bacillus mojavensis strain R3 + SX, Bacillus mojavensis strain SR11 + SX, Bacillus mycoides strain AQ726 + SX, Bacillus mycoides isolate J + SX, Bacillus nematocida + SX, Bacillus nigrificans + SX,Bacillus nigrum + SX, Bacillus popilliae + SX, Bacillus psychrosaccharolyticus + SX, Bacillus pumilus strain AQ717 + SX, Bacillus pumilus strain BUF-33 + SX, Bacillus pumilus strain CCTB05 + SX, Bacillus pumilus strain GB34 + SX, Bacillus pumilus strain QST2808 + SX, Bacillus safensis strain HCX-01 + SX, Bacillus siamensis strain KCTC 13613 + SX, Bacillus simplex strain CGF2856 + SX, Bacillus smithii + SX, Bacillus sp. strain AQ175 + SX, Bacillus sp. strain AQ177 + SX, Bacillus sp. strain AQ178 + SX, Bacillus sphaericus strain 2362 serotype H5a5b + SX Bacillus sphaericus strain ABTS1743 + SX, Bacillus subtilis strain AFS032321 + SX, Bacillus subtilis strain antumavida + SX, Bacillus subtilis strain AP-01 + SX, Bacillus subtilis strain AQ153 + SX, Bacillus subtilis strain AQ743 + SX, Bacillus subtilis strain B246 + SX, Bacillus subtilis strain BU1814 + SX, Bacillus subtilis strain BV02 + SX, Bacillus subtilis strain BV09 + SX, Bacillus subtilis strain C-3102 + SX, Bacillus subtilis strain CCTB04 + SX, Bacillus subtilis strain CX-9060 + SX, Bacillus subtilis strain D747 + SX, Bacillus subtilis strain DB101 + SX, Bacillus subtilis strain DB102 + SX, Bacillus subtilis strain FMCH002 + SX,Bacillus subtilis strain FZB24 + SX, Bacillus subtilis strain GB03 + SX, Bacillus subtilis strain HAI0404 + SX, Bacillus subtilis strain IAB / BS03 + SX, Bacillus subtilis strain MBI600 + SX, Bacillus subtilis strain DSM17231 + SX, Bacillus subtilis strain N5 + SX, Bacillus subtilis strain NCIM2063 + SX, Bacillus subtilis strain NCIM8872 + SX, Bacillus subtilis strain NSRS89-24 + SX, Bacillus subtilis strain PAH17 + SX, Bacillus subtilis strain QST30002 / AQ30002 + SX, Bacillus subtilis strain QST30004 / AQ30004 + SX, Bacillus subtilis strain QST713 + SX, Bacillus subtilis strain QST714 + SX, Bacillus subtilis strain RTI477 + SX,Bacillus subtilis strain S1 + SX, Bacillus subtilis strain S2 + SX, Bacillus subtilis strain SEIBS23 + SX, Bacillus subtilis strain UFPEDA764 + SX, Bacillus subtilis strain Y1336 + SX, Bacillus subtilis strain YL13 + SX, Bacillus subtillis subsp. natto + SX, Bacillus subtilis var. Amyloliquefaciens strain FZB24 + SX, Bacillus tequilensis strain 10b + SX, Bacillus tequilensis strain NII-0943 + SX, Bacillus thuringiensis strain 4042 + SX, Bacillus thuringiensis strain anemophila + SX, Bacillus thuringiensis strain AQ52 + SX, Bacillus thuringiensis strain BD#32 + SX, Bacillus thuringiensis strain CR-371 + SX, Bacillus thuringiensis strain EX297512 + SX,Bacillus thuringiensis subsp. aizawai strain ABTS-1857 + SX, Bacillus thuringiensis subsp. aizawai strain GC-91 + SX, Bacillus thuringiensis subsp. aizawai strain NB200 + SX, Bacillus thuringiensis subsp. aizawai Serotype H-7 + SX, Bacillus thuringiensis subsp. galleriae strain SDS-502 + SX, Bacillus thuringiensis subsp. israelensis strain AM65-52 + SX, Bacillus thuringiensis subsp. israelensis strain AM65-52 serotype H-14 + SX, Bacillus thuringiensis subsp. israelensis strain BMP144 + SX, Bacillus thuringiensis subsp. israelensis strain D142 + SX, Bacillus thuringiensis subsp. israelensis strain EG2215 + SX,Bacillus thuringiensis subsp. israelensis strain SA3A + SX, Bacillus thuringiensis subsp. israelensis strain SUM-6218 + SX, Bacillus thuringiensis subsp. israelensis strain VCRC B17 serotype 11-14 + SX, Bacillus thuringiensis subsp. japonensis + SX, Bacillus thuringiensis subsp. Kurstaki CrylA delta endotoxins + SX, Bacillus thuringiensis subsp. Kurstaki CrylC delta endotoxins + SX, Bacillus thuringiensis subsp. Kurstaki strain 3A3B + SX, Bacillus thuringiensis subsp. Kurstaki strain ABTS351 + SX, Bacillus thuringiensis subsp. Kurstaki strain BMP123 + SX, Bacillus thuringiensis subsp. Kurstaki strain CCT1306 + SX,Bacillus thuringiensis subsp. Kurstaki strain EG2348 + SX, Bacillus thuringiensis subsp. Kurstaki strain EG2371 + SX, Bacillus thuringiensis subsp. Kurstaki strain EG2424 + SX, Bacillus thuringiensis subsp. Kurstaki strain EG7673 + SX, Bacillus thuringiensis subsp. Kurstaki strain EG7826 + SX, Bacillus thuringiensis subsp. Kurstaki strain EG7841 + SX, Bacillus thuringiensis subsp. Kurstaki strain EVB113-19 + SX, Bacillus thuringiensis subsp. Kurstaki strain F810 + SX, Bacillus thuringiensis subsp. Kurstaki strain HD-1 + SX, Bacillus thuringiensis subsp. Kurstaki strain M-200 + SX, Bacillus thuringiensis subsp. Kurstaki strain NCIM2514 + SX, Bacillus thuringiensis subsp. Kurstaki strain PB54 + SX, Bacillus thuringiensis subsp. Kurstaki strain SA-11 + SX, Bacillus thuringiensis subsp. Kurstaki strain SA-12 + SX, Bacillus thuringiensis subsp. Kurstaki strain VBTS-2546 + SX, Bacillus thuringiensis subsp. Kurstaki strain Z-52, serotype H-3a,3b + SX, Bacillus thuringiensis subsp. morrisoni + SX, Bacillus thuringiensis subsp. tenebriosis strain NB 176 + SX, Bacillus thuringiensis subsp. tenebriosis strain SA-10 + SX, Bacillus thuringiensis subsp. thuringiensis strain MPPL002 + SX, Bacillus thuringiensis subsp. var. colmeri + SX,Bacillus thuringiensis subsp. var. darmstadiensis strain 24-91 + SX, Bacillus thuringiensis subsp. var. dendrolimus + SX, Bacillus thuringiensis subsp. var. galleriae + SX, Bacillus thuringiensis subsp. var. japonensis strain buibui + SX, Bacillus thuringiensis subsp. var. aegypti + SX, Bacillus thuringiensis var. 7216 + SX, Bacillus thuringiensis var. sandiego strain M-7 + SX, Bacillus thuringiensis var. T36 + SX, Bacillus velezensis + SX, Bacillus velezensis isolate CNPSo3602 + SX, Bacillus velezensis strain ABi19 + SX, Bacillus velezensis strain FZB42 + SX, Bacillus velezensis strain FZB45 + SX, Bacillus velezensis strain NRRL B-41580 + SX,Bacillus velezensis strain RTI301 + SX, Bradyrhizobium spp. + SX, Bradyrhizobium elkanii + SX, Bradyrhizobium elkanii strain SEMIA 587 + SX, Bradyrhizobium elkanii strain SEMIA 5019 + SX, Bradyrhizobium japonicum + SX, Bradyrhizobium japonicum strain TA-11 + SX, Bradyrhizobium japonicum strain USDA 110 + SX, Bradyrhizobium japonicum strain WB74 + SX, Bradyrhizobium liaoningense + SX, Bradyrhizobium lupini + SX, Bradyrhizobium lupini strain LL13 + SX, Bradyrhizobium spp. (Arachis) + SX, Bradyrhizobium spp. (Vigna) + SX, Brevibacillus brevis strain maguellines I + SX, Brevibacillus brevis strain 2904 + SX, Brevibacillus brevis strain SS86-3 + SX,Brevibacillus brevis strain SS86-4 + SX, Brevibacillus brevis strain SS86-5 + SX, Brevibacillus laterosporus strain ATCC64 + SX, Brevibacillus laterosporus strain BPM3 + SX, Brevibacillus laterosporus strain G4 + SX, Brevibacillus laterosporus strain NCIMB 41419 + SX, Brevibacillus laterosporus strain NRS1111 + SX, Brevibacillus laterosporus strain NRS1645 + SX, Brevibacillus laterosporus strain NRS1647 + SX, Burkholderia ambifaria strain AMMD + SX, Burkholderia cenocepacia strain A396 + SX, Burkholderia cenocepacia strain Ral-3 + SX, Burkholderia cepacia type Wisconsin strain J82 + SX, Burkholderia cepacia type Wisconsin strain M54 + SX,Burkholderia cepacia + SX, Burkholderia gladii strain BA-7 + SX, Burkholderia rinojensis strain A396 + SX, Chromobacterium subtsugae strain PRAA4-1T + SX, Corynebacterium flavescens strain B2575 + SX, Corynebacterium glutamicum + SX, Delftia acidovorans + SX, Delftia acidovorans strain RAY209 + SX, Erwinia carotovora subsp. carotovora strain CGE234M403 + SX, Erwinia gerundensis + SX, Gluconacetobacter diazotrophicus strain IMI504853 + SX, Klebsiella variicola 137 + SX, Kosakonia cowanii strain SYM00028 + SX, Lactobacillus acidophilus + SX, Lactobacillus brevis + SX, Lactobacillus casei strain LPT-111 + SX, Lactobacillus plantarum + SX,Lactobacillus spp. + SX, Lysobacter antibioticus strain 13-1 + SX, Lysobacter enzymogenes strain B25 + SX, Lysobacter enzymogenes strain C3 + SX, Metylobacterium spp. + SX, Methylobacterium isolate ISO01 + SX, Methylobacterium isolate ISO02 + SX, Methylobacterium isolate ISO03 + SX, Methylobacterium isolate ISO04 + SX, Methylobacterium isolate ISO07 + SX, Methylobacterium isolate ISO09 + SX, Methylobacterium isolate ISO10 + SX, Methylobacterium isolate ISO11 + SX, Methylobacterium symbioticum + SX, Mesorhizobium spp. + SX, Mesorhizobium ciceri + SX, Mesorhizobium huakii + SX, Mesorhizobium loti + SX, Paenibacillus alvei strain 2771 + SX,Paenibacillus alvei strain 46C3 + SX, Paenibacillus alvei strain III2E + SX, Paenibacillus alvei strain III3DT-1A + SX, Paenibacillus alvei strain T36 + SX, Paenibacillus macerans + SX, Paenibacillus polymyxa strain AC-1 + SX, Paenibacillus polymyxa strain BS-0105 + SX, Paenibacillus polymyxa strain H-5 + SX, Paenibacillus popilliae + SX, Pantoea agglomerans strain E325 + SX, Pantoea vagans strain C9-1 + SX, Pasteuria nishizawae strain Pn1 + SX, Pasteuria penetrans + SX, Pasteuria ramose + SX, Pasteuria usgae + SX, Pectobacterium carotovorum + SX, Pasteuria thornei + SX, Pseudomonas aeruginosa strain PN1 + SX, Pseudomonas aeruginosa strain WS-1 + SX, Pseudomonas aureofaciens strain TX-1 + SX, Pseudomonas alcaligenes + SX, Pseudomonas cepacia type Wisconsin strain J82 + SX,Pseudomonas cepacia type Wisconsin strain M54 + SX, Pseudomonas chlororaphis strain 63-28 + SX, Pseudomonas chlororaphis strain AFS009 + SX, Pseudomonas chlororaphis strain MA342 + SX, Pseudomonas entomophilla strain 1257 + SX, Pseudomonas fluorescens isolate Pf-5 + SX, Pseudomonas fluorescens strain 1629RS + SX, Pseudomonas fluorescens strain A506 + SX, Pseudomonas fluorescens strain ACK55 + SX, Pseudomonas fluorescens strain CL145A + SX, Pseudomonas fluorescens strain D7 + SX, Pseudomonas fluorescens strain G7090 + SX, Pseudomonas fluorescens biover B strain XJ3 + SX, Pseudomonas fluorescens biover B strain XS18 + SXPseudomonas fluorescens biover A strain LRS12 + SX, Pseudomonas proradix + SX, Pseudomonas putida strain CECT8538 + SX, Pseudomonas reactans + SX, Pseudomonas resinovorans + SX, Pseudomonas rhodesiae strain HAI-0804 + SX, Pseudomonas sp. strain CAB-02 + SX, Pseudomonas sp. strain DSMZ13134 + SX, Pseudomonas syringae strain 742RS + SX, Pseudomonas syringae strain ESC-10 + SX, Pseudomonas syringae strain ESC-11 + SX, Pseudomonas syringae strain MA-4 + SX, Pseudomonas trivialis + SX, Rhizobium etli + SX, Rhizobium galegae + SX, Rhizobium leguminosarum bv. Phaseoli + SX, Rhizobium leguminosarum bv. Trifolii + SX,Rhizobium leguminosarum bv. Viciae + SX, Rhizobium trifolii + SX, Rhizobium tropici + SX, Rhodococcus globerulus strain AQ719 + SX, Saccharopolyspora spinosa + SX, Serratia entomophila strain 626 + SX, Serratia marcescens strain 35 + SX, Serratia marcescens strain SRM + SX, Serratia nematodiphila strain S-CSR-0024 + SX, Sphingobacterium nematocida strain ZY-71-1 + SX, Sinorhizobium fredii + SX, Sinorhizobium meliloti + SX, Streptomyces acidiscabies strain RL-110T + SX, Streptomyces candidus strain Y21007-2 + SX, Streptomyces colombiensis + SX, Streptomyces galbus strain QST6047 + SX, Streptomyces globosus strain LZH-48 + SX,Streptomyces goshikiensis + SX, Streptomyces griseofuscus strain 200101 + SX, Streptomyces griseoviridis strain K61 + SX, Streptomyces jalisciencis isolate CM-CNRG0001 + SX, Streptomyces jofer isolate CM-CNRG0002 + SX, Streptomyces lavendulae + SX, Streptomyces lydicus strain WYCD108US + SX, Streptomyces lydicus strain WYEC108 + SX, Streptomyces microflavus strain AQ6121 + SX, Streptomyces prasinus + SX, Streptomyces rimosus + SX, Streptomyces saraceticus + SX, Streptomyces sp. strain NRRL No.B-30145 + SX, Streptomyces sp. strain WYE20 + SX, Streptomyces sp. strain WYE 324 + SX, Streptomyces venezuelae + SX,Thiobacillus spp. + SX, Variovorax paradoxus strain GF4526 + SX, Virgibacillus pantothenticus strain ATCC14576 + SX, Virgibacillus pantothenticus strain DSM491 + SX, Wolbachia pipientis + SX, Xanthomonas campestris pv poae + SX, Xanthomonas campestris + SX, Xenorhabdus luminescens + SX, Xenorhabdus nematophila + SX.,
[0046] Subgroup (j-2): combination of this component of fungi and yeasts and this compound Acaulospora spp. + SX, Acaulospora longula + SX, Alternaria destruens + SX, Alternaria destruens strain 59 + SX, Ambispora spp. + SX, Ambispora leptoticha + SX, Ampelomyces quisqualis strain AQ10 + SX, Ampelomyces quisqualis strain RSAQ7690 + SX, Ampelomyces quisqualis strain M-10 + SX, Archaeospora spp. + SX, Arkansas Fungus 18 + SX, Arthrobotrys dactyloides + SX, Arthrobotrys superba + SX, Aschersonia aleyrodis + SX, Aspergillus flavus strain AF36 + SX, Aspergillus flavus strain MUCL54911 + SX, Aspergillus flavus strain NRRL21882 + SX, Aureobasidium pullulans strain DSM14940 + SX, Aureobasidium pullulans strain DSM14941 + SX,Aureobasidium pullulans strain YBCA5 + SX, Beauveria bassiana isolate B21 + SX, Beauveria bassiana isolate B33 + SX, Beauveria bassiana isolate CBMAI1306 + SX, Beauveria bassiana strain 147 + SX, Beauveria bassiana strain 203 + SX, Beauveria bassiana strain 447 + SX, Beauveria bassiana strain ANT-03 + SX, Beauveria bassiana strain ATCC74040 + SX, Beauveria bassiana strain ATP02 + SX, Beauveria bassiana strain CFL-A + SX, Beauveria bassiana strain CG716 + SX, Beauveria bassiana strain ESALQ PL63 + SX, Beauveria bassiana strain GHA + SX, Beauveria bassiana strain HF23 + SX, Beauveria bassiana strain IBCB66 + SX, Beauveria bassiana strain IMI389521 + SX,Beauveria bassiana strain J25 + SX, Beauveria bassiana strain NCIM1216 ATCC26851 + SX, Beauveria bassiana strain NPP111B005 + SX, Beauveria bassiana strain PL63 + SX, Beauveria bassiana strain PPRI 5339 + SX, Beauveria bassiana strain R444 + SX, Beauveria bassiana strain ZJU435 + SX, Beauveria brongniartii + SX, Beauveria brongniartii isolate IMBST95.031 + SX, Beauveria brongniartii isolate IMBST95.041 + SX, Candida oleophila strain O + SX, Candida oleophila isolate I-182 + SX, Candida saitoana + SX, Candida spp. + SX, cell walls of Saccharomyces cerevisiae strain LAS117 + SX, Chaetomium cupreum + SX, Chlorella + SX, Chondrostereum purpureum + SX,Cladosporium cladosporioides strain H39 + SX, Claroideoglomus spp. (formerly Glomus spp.) + SX, Claroideoglomus claroideum (formerly Glomus claroideum) + SX, Claroideoglomus etunicatum (formerly Glomus etunicatum) + SX, Claroideoglomus luteum + SX, Clonostachys rosea strain ACM941 + SX, Clonostachys rosea strain CR-7 + SX, Clonostachys rosea strain IDAC 040913-01 + SX, Clonostachys rosea strain J1446 + SX, Colletotrichum gloeosporioides + SX, Conidiobolus obscurus + SX, Conidiobolus thromboide + SX, Coniothyrium minitans strain CGMCC8325 + SX, Coniothyrium minitans strain CON / M / 91-08 + SX, Cryphonectria parasitica + SX, Cryptococcus albidus + SX,Cryptococcus flavescens + SX, Cylindrobasidium laeve + SX, Dactyllela ellipsospora + SX, Dectylaria thaumasia + SX, Dilophosphora alopecuri + SX, Diversispora spp. + SX, Enterococcus faecium + SX, Entomophthora virulenta + SX, Entrophospora spp. + SX, Entyloma ageratinae + SX, Epicoccum nigrum + SX, Funneliformis spp. (formerly Glomus spp.) + SX, Funneliformis mosseae (formerly Glomus mosseae) + SX, Fusarium oxysporum strain Fo47 + SX, Fusarium oxysporum strain RS-21 + SX, Fusarium oxysporum strain RS-25 + SX, Fusarium proliferatum strain NCIM1101 + SX, Geosiphon spp. + SX, Gigaspora spp. + SX, Gigaspora margarita + SX, Gigaspora rosea + SX,Gliocladium catenulatum strain J1446 + SX, Gliocladium roseum + SX, Gliocladium virens strain GL-21 + SX, Glomus spp. + SX, Glomus aggregatum + SX, Glomus deserticola + SX, Glomus etunicatum + SX, Glomus iranicum + SX, Glomus monosporum + SX, Hirsutella minnesotensis + SX, Hirsutella rhossiliensis + SX, Hirsutella thompsonii + SX, Isaria fumosorosea isolate B3 + SX, Isaria fumosorosea strain Isfm-CPF + SX, Isaria tenuipes + SX, Laccaria bicolor + SX, Laccaria laccata + SX, Lagenidium giganteum + SX, Lecanicillium lecanii KV01 + SX, Lecanicillium lecanii conidia of strain DAOM198499 + SX, Lecanicillium lecanii conidia of strain DAOM216596 + SX,Lecanicillium muscarium (formerly Verticillium lecanii) strain 1 / 1 + SX, Lecanicillium muscarium (formerly Verticillium lecanii) strain Ve6 + SX, Metarhizium anisopliae isolate D1 + SX, Metarhizium anisopliae isolate IBCB425 + SX, Metarhizium anisopliae strain CQMa421 + SX, Metarhizium anisopliae strain ESALQ E9 + SX, Metarhizium anisopliae strain ESF1 + SX, Metarhizium anisopliae strain F52 + SX, Metarhizium anisopliae strain FI-985 + SX, Metarhizium anisopliae strain FI-1045 + SX, Metarhizium anisopliae strain ICIPE30 + SX, Metarhizium anisopliae strain ICIPE62 + SX, Metarhizium anisopliae strain ICIPE69 + SX, Metarhizium anisopliae strain ICIPE78 + SX, Metarhizium anisopliae strain NCIM1311 + SX, Metarhizium anisopliae var. acridum strain EVCH077 + SX,Metarhizium anisopliae var. acridum isolate IMI 330189 + SX, Metarhizium anisopliae var. anisopliae BIPESCO 5 / F52 + SX, Metarhizium brunneum strain Cb15-III + SX, Metarhizium flavoviride strain F001 + SX, Metarhizium rileyi strain PHP1705 + SX, Metschnikowia fructicola strain NRRLY-27328 + SX, Metschnikowia fructicola strain NRRLY-30752 + SX, Microdochium dimerum strain L13 + SX, Microsphaeropsis ochracea + SX, Monacrosporium phymatopagum + SX, Mucor hiemalis + SX, Muscodor albus strain 620 + SX, Muscodor albus strain QST 20799 + SX, Muscodor albus strain SA13 + SX, Muscodor roseus strain A3-5 + SX,Myrothecium verrucaria strain AARC-0255 + SX, Nomuraea rileyi strain CG128 + SX, Nomuraea rileyi strain GU87401 + SX, Nomuraea rileyi strain SA86101 + SX, Nomuraea rileyi strain SR86151 + SX, Nomuraea rileyi strain VA9101 + SX, Ophiostoma piliferum strain D97 + SX, Pacispora spp. + SX, Paecilomyces fumosoroseus Apopka strain 97, Now, Isaria fumosorosea Apopka strain 97 + SX, Paecilomyces fumosoroseus strain FE9901, Now, Isaria fumosorosea strain FE9901 + SX, Paecilomyces lilacinus strain 251 + SX, Paecilomyces tenuipes strain T1 + SX, Paecilomyces variotii strain Q-09 + SX, Pandora delphacis + SX, Paraglomus spp. + SX,Paraglomus brasilianum (formerly Glomus brasilianum) + SX, Penicillium bilaiae strain ATCC22348 + SX, Penicillium citrinum strain VFI-51 + SX, Penicillium vermiculatum + SX, Phlebiopsis gigantea strain FOC PG410.3 + SX, Phlebiopsis gigantea strain VRA1835 + SX, Phlebiopsis gigantea strain VRA1984 + SX, Phlebiopsis gigantea strain VRA1985 + SX, Phlebiopsis gigantea strain VRA1986 + SX, Phlebiopsis gigantea strain VRA1992 + SX, Phlebiopsis spp. + SX, Phoma macrostroma strain 94-44B + SX, Phytophthora palmivora + SX, Pichia anomala strain WRL-076 + SX, Pichia guilliermondii strain Z1 + SX, Pichia guilliermondii strain Z8 + SX, Pisolithus tinctorius + SX,Pochonia chlamydosporia isolate strain PC10 + SX, Pochonia chlamydosporia + SX, Pseudozyma flocculosa strain ATTC64874 + SX, Pseudozyma flocculosa strain PF-A22UL + SX, Puccinia thlaspeos strain woad + SX, Purpureocillium lilacinum strain 251 + SX, Purpureocillium lilacinum strain PL11 + SX, Pythium oligandrum strain DV74 + SX, Pythium oligandrum strain M1 + SX, Racocetra spp. + SX, Rhizophagus spp. (formerly Glomus spp.) + SX, Rhizophagus clarus (formerly Glomus clarum) + SX, Rhizophagus intraradices (formerly Glomus intraradices) + SX, Rhizophagus intraradices strain RTI-801 + SX, Rhizophagus irregularis (formerly Glomus intraradices) + SX, Rhizophagus irregularis strain DAOM 197198 + SXScutellospora spp. + SX, Rhizopogon amylopogon + SX, Rhizopogon fulvigleba + SX, Rhizopogon luteolus + SX, Rhizopogon villosullus + SX, Saccharomyces cerevisiae strain LAS02 + SX, Saccharomyces cerevisiae strain DDSF623 + SX, Saccharomyces cerevisiae strain SP.1026 + SX, Scleroderma cepa + SX, Scleroderma citrinum + SX, Sclerotinia minor strain IMI34414 + SX, Sporothrix insectorum + SX, Suillus granulatus + SX, Suillus punctatapies + SX, Talaromyces flavus strain SAY-Y-94-01 + SX, Talaromyces flavus strain V117b + SX, Trichoderma afroharzianum + SX, Trichoderma album + SX, Trichoderma asperelloides strain JM41R + SX,Trichoderma asperellum strain CBMAI840 + SX, Trichoderma asperellum strain CBMAI1622 + SX, Trichoderma asperellum strain BV09 + SX, Trichoderma asperellum strain BV10 + SX, Trichoderma asperellum strain ICC012 + SX, Trichoderma asperellum strain kd + SX, Trichoderma asperellum strain M103 + SX, Trichoderma asperellum strain RNCIM F-1323 + SX, Trichoderma asperellum T11 + SX, Trichoderma asperellum T25 + SX, Trichoderma asperellum strain T34 + SX, Trichoderma asperellum strain SKT-1 + SX, Trichoderma asperellum strain TV1 + SX, Trichoderma atroviride strain 77B + SX, Trichoderma atroviride strain CNCM 1-1237 + SX, Trichoderma atroviride strain I-1237 + SX, Trichoderma atroviride strain IMI 206040 + SX, Trichoderma atroviride strain K4 + SX, Trichoderma atroviride strain LC52 + SX, Trichoderma atroviride strain LU132 + SX, Trichoderma atroviride strain SC1 + SX, Trichoderma atroviride strain SKT-1 + SX, Trichoderma atroviride strain T11 + SX, Trichoderma atroviride strain TV1 + SX, Trichoderma atroviride strain WW10TC4 + SX, Trichoderma gamsii strain ICC080 + SX, Trichoderma harmatum strain 382 + SX, Trichoderma harmatum strain TH382 + SX, Trichoderma harzianum strain 21 + SX,Trichoderma harzianum strain AP-001 + SX, Trichoderma harzianum strain BK-Th001 + SX, Trichoderma harzianum strain CBS101525 + SX, Trichoderma harzianum strain DB 104 + SX, Trichoderma harzianum strain DSM 14944 + SX, Trichoderma harzianum strain ESALQ-1303 + SX, Trichoderma harzianum strain ESALQ-1306 + SX, Trichoderma harzianum strain F11Bab + SX, Trichoderma harzianum strain Gomorteka + SX, Trichoderma harzianum strain IB19 / 17 + SX, Trichoderma harzianum strain IBLF006 + SX, Trichoderma harzianum strain IIHR-Th-2 + SX, Trichoderma harzianum strain ITEM908 + SX, Trichoderma harzianum strain K2 + SX, Trichoderma harzianum strain kd + SX,Trichoderma harzianum strain KRL-AG2 + SX, Trichoderma harzianum strain MO1 + SX, Trichoderma harzianum strain queule + SX, Trichoderma harzianum strain RR17Bc + SX, Trichoderma harzianum strain SF + SX, Trichoderma harzianum strain T5 + SX, Trichoderma harzianum strain T22 + SX, Trichoderma harzianum strain T24 + SX, Trichoderma harzianum strain T39 + SX, Trichoderma harzianum strain T78 + SX, Trichoderma harzianum strain TH35 + SX, Trichoderma harzianum strain TH315 + SX, Trichoderma harzianum rifai + SX, Trichoderma koningii + SX, Trichoderma lignorum strain TL-0601 + SX, Trichoderma lignorum + SX, Trichoderma longibrachiatum strain T-397 + SX,Trichoderma polysporum strain IMI206039 + SX, Trichoderma parceramosum + SX, Trichoderma reesei + SX, Trichoderma strain SKT-1 + SX, Trichoderma spp. + SX, Trichoderma saturnisporium strain PBP-TH-001 + SX, Trichoderma stromaticum + SX, Trichoderma virens strain chagual + SX, Trichoderma virens strain G-41 + SX, Trichoderma virens strain GL-21 (formaly Gliocladium virens GL-21) + SX, Trichoderma virens strain nire + SX, Trichoderma virens strain sherwood + SX, Trichoderma viride strain (NRRL B-50520) + SX, Trichoderma viride strain K5 + SX, Trichoderma viride strain T111 + SX, Tsukamurella paurometabola strain C-924 + SX, Tsukamurella paurometabola + SX,Typhula phacorrhiza strain 94671 + SX, Ulocladium oudemansii strain HRU3 + SX, Ulocladium oudemansii strain U3 + SX, Verticillium alboatrum strain WCS850 + SX, Verticillium chlamydosporium + SX, Verticillium dahliae + SX, Verticillium lecanii strain ID05-F0117 + SX, Verticillium lecanii strain NCIM1312 + SX, Verticillium lecanii strain SZWL7 + SX, Zoophtora radicans + SX.,
[0047] Subgroup (j-3): combination of this component of protozoa and this compound: Nosema locustae + SX, Thelohania solenopsis + SX, Vairimorpha spp. strain Q-09 + SX.
[0048] Subgroup (j-4): combination of this component of virus and this compound: Adoxophyes orana granulovirus strain BV-0001 + SX, Agrotis segetum nucleopolyhedrovirus + SX, Anagraoha falcifera nucleopolyhedrovirus + SX, Anticarsia gemmatalis multiple nucleocapsid nucleopolyhedrovirus + SX, Autographa californica MNPV strain FV11 + SX, Autographa californica MNPV strain R3 + SX, Bacteriophage of Clavibacter michiganesis + SX, Bacteriophage active against Clavibacter michiganensis subsp. michiganensis + SX, Bacteriophage active against Erwinia amylovora + SX, Bacteriophage active against Pseudomonas syringae pv. tomato + SX, Bacteriophage active against Xanthomonas campestris pv. vesicatoria + SX, Bacteriophage active against Xanthomonas citri subsp. citri + SX, Bacteriophage against Xylella fastidiosa + SX, Biston suppressaria NPV + SX, Bombyx mori NPV + SX,Chrysodeixis includens NPV isolate 460 + SX, Cryptophlebia leucotreta GV + SX, Cydia pomonella GV + SX, Cydia pomonella GV M + SX, Cydia pomonella GV strain CP4 + SX, Cydia pomonella GV strain R5 + SX, Cydia pomonella GV strain V15 + SX, Cydia pomonella GV strain V22 + SX, Douglas fir tussock moth NPV + SX, Dendrolimus punctatus cypovirus + SX, Ectropis obliqua picorna-like virus + SX, Helicoverpa armigera NPV + SX, Helicoverpa armigera NPV strain BV-0003 + SX, Helicoverpa zea NPV + SX, Indian meal moth GV + SX, Leucoma salicis NPV + SX, Lymantria dispar MNPV + SX, Mamestra brassicae NPV + SX,Mamestra configurata NPV + SX, Neodiprion abietis NPV + SX, Neodiprion lecontei NPV + SX, Neodiprion sertifer NPV + SX, Orgyia pseudotsugata NPV + SX, pepino mosaic virus strain CH2 isolate 1906 + SX, pepino mosaic virus strain CH2 isolate Abp1 + SX, pepino mosaic virus strain CH2 isolate Abp2 + SX, pepino mosaic virus isolate VC1 + SX, pepino mosaic virus isolate VX1 + SX, Phthorimaea operculella GV isolate DSMZ GV - 0019 + SX, Pieris rapae GV + SX, Plodia interpunctella GV + SX, Plutella xylostella GV + SX, Spodoptera albula MNPV + SX, Spodoptera exempta MNPV + SX,Spodoptera exigua multiple nucleopolyhedrovirus strain BV-0004 + SX, Spodoptera frugiperda multiple nucleopolyhedrovirus + SX, Spodoptera littoralis multiple nucleopolyhedrovirus isolate DSMZ BV-0005 + SX, Spodoptera litura nucleopolyhedrovirus + SX, Tobacco mild tobamovirus strain U2 + SX, Zucchini Yellow Mosaik Virus weak strain + SX.,
[0049] Subgroup (j-5): combination of the main component of nematodes and this compound: Abbreviata caucasica + SX, Acuaria spp. + SX, Agamermis decaudata + SX, Allantonema spp. + SX, Amphimermis spp. + SX, Deladenus siricidicola + SX, Bovienema spp. + SX, Cameronia spp. + SX, Chitwoodiella ovofilamenta + SX, Contortylenchus spp. + SX, Culicimermis spp. + SX, Diplotriaena spp. + SX, Empidomermis spp. + SX, Filipjevimermis leipsandra + SX, Gastromermis spp. + SX, Gongylonema spp.) + SX, *Gynopoecilia pseudovipara* + SX, *Heterorhabditis bacteriophora* + SX, *Heterorhabditis baujardi* + SX, *Heterorhabditis downesi* + SX, *Heterorhabditis heliothidis* + SX, *Heterorhabditis indica* + SX, *Heterorhabditis marelatus* + SX, *Heterorhabditis megidis* + SX, *Heterorhabditis zealandica* + SX, *Hexamermis spp.* + SX, *Hydromermis spp.* + SX, *Isomermis spp.* + SX, *Limnomermis spp.* + SX, *Maupasina weissi* + SX, *Mermis nigrescens* + SX, *Mesomermis spp.* + SX, *Neomesomermis spp.* + SX, *Neoparasitylenchus rugulosi* + SX, *Octomyomermis spp.* + SX, *Parasitaphelenchus spp.* + SX, *Parasitorhabditis spp.* + SX, *Parasitylenchus spp.) + SX, Perutilimermis culicis + SX, Phasmarhabditis hermaphrodita isolate DDT M1 + SX, Physaloptera spp. + SX, Protrellatus spp. + SX, Pterygodermatites spp. + SX, Romanomermis spp. + SX, Seuratum cadarachense + SX, Sphaerulariopsis spp. + SX, Spirura guianensis + SX, Steinernema bibionis + SX, Steinernema carpocapsae + SX, Steinernema feltiae isolate DDT D2 + SX, Steinernema glaseri + SX, Steinernema indica + SX, Steinernema kraussei + SX, Steinernema riobrave + SX, Steinernema scapterisci + SX, Steinernema scarabaei + SX, Steinernema siamkayai + SX, Steinernema thailandse + SX, Steinernema spp.) + SX, Strelkovimermis peterseni + SX, Subulura spp. + SX, Sulphuretylenchus elongatus + SX, Tetrameres spp. + SX.
[0050] Subgroup (j-6): Combination of the present component of the natural product and the present compound: (2S,3R,4R,5S)-2,5-bis(hydroxymethyl)pyrrolidine-3,4-diol + SX, 1,4-dimethylnaphthalene + SX, 2-methyl-1-butanol + SX, 2-phenylethyl propionate + SX, 9,21-didehydroryanodine + SX, alizarin 2-glucoside + SX, dihydroazadirachtin + SX, ethyl 3-[acetyl(butyl)amino]propanoate + SX, glycerol monocaprate + SX, glycerol monocaprylate + SX, glycerol monolaurate + SX, heptyl butyrate + SX, methyl anthranilate + SX, methyl nonyl ketone + SX, methyl Salicylate + SX, N-(3-methyl-2-buten-1-yl)-9H-purin-6-amine + SX, N,N'-diformylurea + SX, octanal + SX, oxypurinol + SX, p-cymene + SX, p-menthane-3,8-diol + SX, phenazine-1-carboxylic acid + SX, propylene glycol monocaprylate + SX, propylene glycol monolaurate + SX, sorbitol octanoate + SX, sucrose octanoate + SX, terpinen-4-ol + SX, balsam fir oil (Abies balsamea oil) + SX, α-ionone + SX, β-citronellol + SX, gamma-Terpinene + SX, ammonium bicarbonate + SX, anabasine + SX, anise oil + SX,Ascaridole + SX, Azadirachtin + SX, Bark of Celastrus angulatus + SX, Brassica juncea + SX, Brassinolide + SX, Bacillus thuringiensis Cry1Ab protein + SX, Bacillus thuringiensis Cry1Ac protein + SX, Bacillus thuringiensis Cry1Fa protein + SX, Bacillus thuringiensis Cry1A.105 protein + SX, Bacillus thuringiensis Cry2Ab protein + SX, Bacillus thuringiensis Vip3A protein + SX, Bacillus thuringiensis mCry3A protein + SX, Bacillus thuringiensis Cry3Ab protein + SX, Bacillus thuringiensis Cry3Bb protein + SX,Bacillus thuringiensis-derived Cry34Ab1 / Cry35Ab1 protein + SX, insecticidal protein Tma12 derived from the fern Tectaria macrodonta + SX, insecticidal protein IPD083 derived from the fern Adiantum spp. + SX, insecticidal protein IPD113 derived from Pteris cretica cv. albolineata or Pteris umbrosa + SX, calcium acetate + SX, calcium lactate + SX, calcium polysulfide + SX, Canola oil + SX, capsicin + SX, Capsicum oleoresin + SX, Castor oil + SX, Cedarwood oil + SX, cevadine + SX, chitin + SX, Chitosan + SX, chlorophyllin + SX, chlortetracycline + SX, cinerin I + SX, cinerin II + SX, cinnamaldehyde + SX, cis-jasmone + SX, citral + SX, citric acid + SX,Citronella oil + SX, Citrus bergamia fruit oil + SX, clarified hydrophobic extract of neem oil + SX, Clove oil + SX, Collagen protein hydrolysate + SX, colletochlorin B + SX, concanamycin A + SX, cottonseed oil + SX, cytokinin + SX, cow's milk + SX, deguelin + SX, diallyl sulfide + SX, d-limonene + SX, dried leaves of Dryopteris filix-mas + SX, Ea peptide 91398 + SX, eucalyptol + SX, extract of Acacia mearnsii + SX, extract of Achillea fragrantissima + SX, extract of Allium cepa + SX, extract of Allium sativum + SX, extract of Anethum graveolens + SX, extract of Annona squamosa + SX, extract of Arctium lappa + SX, extract of Artemisia absinthium + SX, extract of Artocarpus heterophyllus + SX,Extract of Azadirachta indica + SX, Extract of Calendula officinalis + SX, Extract of Camelia sinensis + SX, Extract of Capsicum annuum + SX, Extract of Cassia nigricans + SX, Extract of Chenopodium ambrosioides + SX, Extract of Chenopodium quinoa + SX, Extract of Cinnamomum verum + SX, Extract of Clitoria ternatea + SX, Extract of the cotyledons of lupine plantlets ("BLAD") + SX, Extract of Daphne gnidium + SX, Extract of Equisetum arvense + SX, Extract of Equisetum giganteum + SX, Extract of Galenia africana + SX, Extract of green tea + SX, Extract of Liliaceae + SX, Extract of Macleaya + SX, Extract of Matricaria chamomilla + SX, Extract of Melaleuca alternifolia + SX, Extract of Millettia pinnata + SX,Extract of Opuntia lindheimeri + SX, extract of Origanum vulgare + SX, extract of Piper auritum + SX, extract of Pyrethrum, extract of Quercus falcata + SX, extract of Quillaja saponaria + SX, extract of Reynoutria sachalinensis + SX, extract of Rhamnus utilis + SX, extract of Rhus aromatica + SX, extract of Rheum officinale + SX, extract of Rhizophora mangle + SX, extract of Rosmarinus officinalis + SX, extract of Ruta chalepensis + SX, extract of Schoenocaulon spp. seed + SX, extract of Sweet lupin seed + SX, extract of Swinglea glutinosa + SX, extract of Symphytum officinale + SX, extract of Sweet lupinseed + SX, extract of Tagetes erecta + SX, extract of Tanacetum vulgare + SX, extract of Thymus vulgaris + SX,Nasturtium extract + SX, Nettle extract + SX, Mistletoe extract + SX, Yucca schidigera extract + SX, Fenugreek seed powder + SX, Fish oil + SX, Formic acid + SX, Geraniol + SX, Ginkgolide A + SX, Ginkgolide B + SX, Ginkgolide C + SX, Ginkgolide J + SX, Ginkgolide M + SX, Gougerotin + SX, GS-omega / kappa HXTX-Hv1a peptide + SX, Harpin protein + SX, Hydrogenated castor oil + SX, Hydroprene + SX, Star anise oil + SX, Ivermectin + SX, Jasmolin I + SX, Jasmolin II + SX, Jojoba oil + SX, Karanjin + SX, Kasugamycin + SX, Kinoprene + SX, Laminarine + SX, L-ascorbic acid + SX, Oak leaves and bark + SX, Lemongrass oil + SX, L-glutamic acid + SX, Linalool + SX,Linseed oil + SX, Lobularia maritima + SX, lysophosphatidylethanolamine + SX, maltodextrin + SX, matrine + SX, matrine N-oxide + SX, menthol + SX, methoprene + SX, Milbemycin A4 + SX, Mildiomycin + SX, Natamycin + SX, Nemadectin + SX, Nepeta cataria oil + SX, Nootkatone + SX, Oil of the seeds of Chenopodium anthelminticum + SX, Orange oil + SX, Pelargonium odoratissimum oil + SX, Pellitorine + SX, Piperine + SX, Piper nigrum seed oil + SX, Polyoxin B + SX, Polyoxorim + SX, Potassium phosphonate + SX, Potassium silicate + SX, Precocene II + SX, Putrescent whole egg solids + SX, Pyrethrin I + SX, Pyrethrin II + SX, Quillaja extract + SX, Rotenone + SX, Rapeseed oil + SX, Rhamnolipid + SX, Ryanodine + SX, Rosemary oil + SX, Sabadilla + SX, Salicylic acid + SX, Sanguinarine + SX, Saponins of Chenopodium quinoa + SX, Sesame oil + SX, Soy lecithin + SX,Soybean oil + SX, spinosad + SX, Squamocin + SX, streptomycin + SX, sunflower oil + SX, Tagetes oil + SX, terpene constituents of the extract of chenopodium ambrosioides near ambrosioides, Brand name: Terpenoid blend QRD 460 + SX, Thyme oil + SX, thymol + SX, trypsin modulating oostatic factor + SX, Veratrine + SX, veratridine + SX, wood extract of Quassia amara + SX, Xanthine + SX, yellow mustard powder + SX.,
[0051] Subgroup (j-7): Combinations of the essential components of the insect and this compound: Two-spotted ladybird (Adalia bipunctata) + SX, Amitus hesperidum + SX, Amitus spiniferus + SX, Anagrus atomus + SX, Anagrus epos + SX, Anagyrus fusciventris + SX, Anagyrus fusciventris + SX, Anagyrus pseudococci + SX, Anaphes flavipes + SX, Parasitic wasp (Anaphes iole) + SX, Anaphes nitens + SX, Anastatus tenuipes + SX, Anthocoris nemoralis + SX, Aphelinus abdominalis + SX, Aphelinus asychis + SX, Aphelinus mali + SX, Aphelinus semiflavus + SX, Aphidius colemani + SX, Aphidius ervi + SX, Aphidius gifuensis + SX, Aphidius matricariae + SX, Aphidius smithi + SX, Aphidoletes aphidimyza + SX, Aphytis holoxanthus + SX, Aphytis lepidosaphes + SX, Aphytis lignanensis + SX, Aphytis melinus + SX, Aphytis mytilaspidis + SX, Apion fuscirostre + SX, Apion ulicis + SX, Aprostocetus hagenowii + SX, Avetianella longoi + SX, Bangasternus orientalis + SX, Bathyplectes anurus + SX, Bathyplectes curculionis + SX, Bracon cushmani + SX,Bracon gelechiae + SX, Bracon hebetor + SX, Cales noacki + SX, Calosoma sycophanta + SX, Carcinops pumillio + SX, Catolaccus grandis + SX, Cephalonomia tarsalis + SX, Chilocorus baileyi + SX, Chilocorus bipustulatus + SX, Chilocorus circumdatus + SX, Chilocorus kuwanae + SX, Chilocorus nigritus + SX, Chilocorus stigma + SX, Chrysoperla carnea + SX, Chrysoperla rufilabris + SX, Clitostethus arcuatus + SX, Coccidoxenoides perminutus + SX, Coccophagus cowperi + SX, Coccophagus lycimnia + SX, Coenosia attenuata + SX, Coleomegilla maculata + SX, Comperia merceti + SX, Comperiella bifascita + SX, Copidosoma floridanum + SX, Copidosoma truncatellum + SX, Cotesia flavipes + SX, Cotesia glomerata + SX, Cotesia marginiventris + SX, Cotesia medicaginis + SX, Cotesia melanoscela + SX, Cotesia plutellae + SX, Cotesia ruficrus + SX, Cryptolaemus montrouzieri + SX, Cybocephalus nipponicus + SX,Dacnusa sibirica + SX, Dalotia coriaria + SX, Delphastus catalinae + SX, Delphastus pusillus + SX, Dendrolimus punctatus + SX, Deraeocoris brevis + SX, Diaeretiella rapae + SX, Dicyphus hesperus + SX, Diglyphus isaea + SX, Encarsia aurantii + SX, Encarsia formosa + SX, Encarsia inaron + SX, Encarsia opulenta + SX, Encarsia perplexa + SX, Ephedrus cerasicola + SX, Episyrphus balteatus + SX, Eretmocerus eremicus + SX, Eretmocerus mundus + SX, Feltiella acarisuga + SX, Franklinothrips megalops + SX, Franklinothrips orizabensis + SX, Franklinothrips vespiformis + SX, Geocoris punctipes + SX, Glyptapanteles liparidis + SX, Goniozus legneri + SX, Harmonia axyridis + SX, Hippodamia convergens + SX, Hyposoter exiguae + SX, Hyposoter fugitivus + SX, Lariophagus distinguendus + SX, Leptomastidea abnormis + SX, Leptomastix algirica + SX, Leptomastix dactylopii + SX,Long-tailed parasitoid wasp (Leptomastix epona) + SX, Lydella thompsoni + SX, Lysiphlebus testaceipes + SX, Macrocentrus ancylivorus + SX, Macrocentrus iridescens + SX, Macrolophus pygmaeus + SX, Mallada signata + SX, Metaphycus bartletti + SX, Metaphycus californicus + SX, Metaphycus flavus + SX, Metaphycus funicularis + SX, Metaphycus helvolus + SX, Metaphycus luteolus + SX, Metaphycus stanleyi + SX, Meteorus autographae + SX, Meteorus laphygmae + SX, Meteorus pulchricornis + SX, Meteorus trachynotus + SX, Metoecus paradoxus + SX, Microctonus aethiopoides + SX, Angular-winged fly (Micromus angulatus) + SX, Micromus tasmaniae + SX, Micromus variegatus + SX, Microplitis brassicae + SX, Microplitis plutellae + SX, Microterys flavus + SX, Muscidifurax raptor + SX, Muscidifurax raptorellus + SX, Nabis kinbergii + SX, Necremnus artynes + SX, Neochrysocharis formosa + SX, Neodryinus typhlocybae + SX, Nesidiocoris tenuis + SX, Orius albidipennis + SX, Orius armatus + SX, Orius insidiosus + SX, Orius laevigatus + SX,Orius majusculus + SX, Orius niger + SX, Orius strigicollis + SX, Orygia pseudotsugata + SX, Pediobius foveolatus + SX, Pentalitomastix plethorica + SX, Pnigalio flavipes + SX, Podisus maculiventris + SX, Praon volucre + SX, Pseudaphycus maculipennis + SX, Psyllaephagus pilosus + SX, Rhapalosiphum padi + SX, Rhizophagus grandis + SX, Rhyzobius forestieri + SX, Rhyzobius lophantae + SX, Vedalia beetle (Rodolia cardinalis) + SX, Scolothrips sexmaculatus + SX, Serangium parcesetosum + SX, Spalangia cameroni + SX, Spalangia endius + SX, Stethorus punctillum + SX, Sympiesis stigmata + SX, Telenomus podisi + SX, Chinese mantis (Tenodera sinensis) + SX, Tetrastichus brevistigma + SX, Tetrastichus gallerucae + SX, Tetrastichus howardi + SX, Tetrastichus setifer + SX, Thripobius semiluteus + SX, Chinese long-tailed wasp (Torymus sinensis) + SX, Trichogramma achaeae + SX, Trichogramma brassicae + SX, Trichogramma evanescens + SX, Trichogramma minutum + SX, Trichogramma ostriniae + SX, Trichogramma platneri + SX,Trichogramma pretiosum + SX, Trichogramma semifumatum + SX, Trichogrammatoidea bactrae + SX, Trichopoda pennipes + SX, Trioxys complanatus + SX, Trioxys curvicaudus + SX, Trioxys pallidus + SX, Trioxys tenuicaudus + SX, Trissolcus basalis + SX, Vairimorpha necatrix + SX, Volucella inanis + SX, Voria ruralis + SX, Southern flea bug (Xylocoris flavipes) + SX, Zelus renardii + SX.,
[0052] Subgroup (j-8): Combination of the main components of mites and this compound: Amblydromalus limonicus + SX, Amblyseius andersoni + SX, Amblyseius barkeri + SX, Amblyseius californicus + SX, Amblyseius cucumeris + SX, Amblyseius degenerans + SX, Amblyseius montdorensis + SX, Amblyseius swirskii + SX, Amblyseius womersleyi + SX, Anystis agilis + SX, Cheyletus eruditus + SX, Euseius gallicus + SX, Euseius stipulatus + SX, Euseius tularensis + SX, Gaeolaelaps gillespiei + SX, Galendromus annectens + SX, Galendromus helveolus + SX, Galendromus occidentalis + SX, Hypoaspis aculeifer + SX, Hypoaspis miles + SX, Macrocheles robustulus + SX, Mesoseiulus longipes + SX, Neoseiulus fallacis + SX, Phytoseiulus macropilis + SX, Phytoseiulus persimilis + SX, Thyreophagus entomophagus + SX, Typhlodromus pyri + SX。
[0053] Subgroup (j-9): Combination of the present component of the mollusk and the present compound: Rumina decollata + SX。
[0054] The component selected from group (j) is usually prepared by methods known in the art. For example, in the case of (j-1) bacteria or (j-2) fungi / yeasts, it is prepared using media and fermentation methods known in the art. When this component is (j-1) bacteria or (j-2) fungi / yeasts, the preparation contains 4 ~1×10 13 CFU (colony forming units), preferably 1×10 8 ~1×10 12 CFU of this component per gram. When this component is (j-4) virus, the preparation contains 1×10 4 ~1×10 13 occlusion bodies (sometimes denoted as Obs), preferably 1×10 8 ~1×10 12 occlusion bodies (sometimes denoted as Obs) of this component per gram. When this component is (j-5) nematode, the preparation contains 1×10 4 ~1×10 13 individuals, preferably 1×10 8 ~1×10 12 individuals of this component.
[0055] This compound can be mixed or used in combination with chemical fertilizers (such as ammonium sulfate, superphosphate, ammonium nitrate, urea, ammonium chloride, etc.).
[0056] The weight ratio of the application rate of this compound to the application rate of this component in composition A is not particularly limited, but can be appropriately adjusted to an optimal weight ratio depending on the type of plant to be protected, the type and occurrence frequency of harmful arthropods, harmful nematodes, harmful mollusks, phytopathogenic microorganisms or weeds to be controlled, the formulation form, the application time, the application method, the application location, the weather conditions, etc. For example, in the agricultural field, when applying to plants (especially foliage, seeds, vegetative reproductive organs) or when applying to the cultivation carrier (especially soil) for cultivating plants, the following weight ratios can be mentioned. In addition, the weight of the present component selected from group (j) means the weight of the preparation thereof. For example, a weight ratio of 1:500 means that the application amount of the preparation of one or more components selected from group (j) is 500 parts by weight with respect to 1 part by weight of the present compound.
[0057] Weight ratio [(this compound):(this component)] = 1:10^15 to 10^15:1. Specifically, for example, approximately, 1:10^15, 1:10^14, 1:10^13, 1:10^12, 1:10^11, 1:10^10, 1:10^9, 1:10^8, 1:10^7, 1:10^6, 1:10^5, 1:10000, 1:9000, 1:8000, 1:7000, 1:6000, 1:5000, 1:4000, 1:3000, 1:2000, 1:1000, 1:900, 1:800, 1:700, 1:600, 1:500, 1:400, 1:350, 1:300, 1:250, 1:200, 1:150, 1:100, 1:90, 1:80, 1:70, 1:60, 1:50, 1:40, 1:30, 1:20, 1:19, 1:18, 1:17, 1:16, 1:15, 1:14, 1:13, 1:12, 1:11, 1:10, 1:9, 1:8, 1:7, 1:6, 1:5, 2:9, 1:4, 2:7, 3:10, 1:3, 3:8, 2:5, 3:7, 4:9, 1:2, 5:9, 4:7, 3:5, 5:8, 2:3, 7:10, 5:7, 3:4, 7:9, 4:5, 5:6, 6:7, 7:8, 8:9, 9:10, 1:1, 10:9, 9:8, 8:7, 7:6, 6:5, 5:4, 9:7, 4:3, 7:5, 10:7, 3:2, 8:5, 5:3, 7:4, 9:5, 2:1, 9:4, 7:3, 5:2, 8:3, 3:1, 10:3, 7:2, 4:1, 9:2, 5:1, 6:1, 7:1, 8:1, 9:1, 10:1, 11:1, 12:1, 13:1, 14:1, 15:1, 16:1, 17:1, 18:1, 19:1, 20:1, 30:1, 40:1, 50:1, 60:1, 70:1, 80:1, 90:1, 100:1, 150:1, 200:1, 250:1, 300:1, 400:1, 500:1, 600:1, 700:1, 800:1, 900:1, 1000:1, 2000:1, 3000:1, 4000:1, 5000:1, 6000:1, 7000:1, 8000:1, 9000:1, 10000:1, 10^5:1, 10^6:1, 10^7:1, 10^8:1, 10^9:1, 10^10:1, 10^11:1, 10^12:1, 10^13:1, 10^14:1, 10^15:1. Here, the caret symbol " ^ " is an operator representing exponentiation. For example, "10^5" is "10 5"(i.e., 10 to the 5th power). The approximate range in the previous paragraph includes a range of ratios that are increased or decreased by 10% by weight with respect to the specified ratio. For example, if it is approximately 1:2, it includes the range of 1:1.8 to 1:2.2.
[0058] This compound or composition A is usually used as a composition (hereinafter referred to as composition B) further containing an inert carrier. Composition B is usually prepared by mixing this compound or composition A with a solid carrier, a liquid carrier, a surfactant, etc., and adding formulation aids such as a binder, a dispersant, a stabilizer, and a gas as necessary, and formulating it into an aqueous suspension formulation, an oily suspension formulation, an emulsion, an emulsion formulation, a microemulsion formulation, a microcapsule formulation, a wettable powder, a granular wettable powder, a powder, a granule, a tablet, an aerosol, a resin formulation, etc. It can be formulated and used not only in these formulations but also in the dosage forms described in Manual on development and use of FAO and WHO Specifications for pesticides, FAO Plant Production and Protection Papers - 271~276, prepared by the FAO / WHO Joint Meeting on Pesticide Specifications, 2016, ISSN:0259-2517. In addition, composition B can be used, for example, as a spray (aerosol, pump spray, ultrasonic vibration type formulation, electrostatic spray type formulation, etc.), a bait agent, an incendiary agent (such as a mosquito coil), a heating evaporation agent (electric mosquito mat, liquid mosquito repellent formulation, etc.), a blowing evaporation agent (fan type mosquito repellent formulation, etc.), a fumigant (self-combustible type fumigant, chemical reaction type fumigant, porous ceramic plate fumigant, etc.), a fumigation agent, a smoke agent, an ultra-low volume (ULV) agent, a mist agent, a foam agent, a paste-like formulation, a paint, a wood protection paint, a sealing material, a carbon dioxide gas formulation, a sheet formulation, a tape formulation, a paper formulation, a non-woven fabric formulation, an animal collar, an animal ear tag, a shampoo, a spot-on agent, a pour-on agent, a suppository, an injection, an oral treatment agent (capsule, tablet, chewable, feed, etc.), a sublimable tablet, a mosquito net, an attractant cord, a gardening support, a screen door, etc. These formulations usually contain this compound in a weight ratio of 0.0001 to 99%, preferably 0.1 to 99%, more preferably 0.2 to 90%.
[0059] When formulating this compound or composition A into an aqueous suspension formulation, an oily suspension formulation, a wettable powder, or a granule wettable powder, the particle size of this compound or composition A is usually in the range of 0.1 to 20 μm, preferably 0.2 μm to 15 μm. Also, when formulating this compound or composition A into granules, the particle size of this compound or composition A is usually in the range of 0.1 to 200 μm, preferably 0.5 μm to 100 μm. The particle size of this compound or composition A means the particle size (volume median diameter) at which the cumulative frequency is 50% in the volume-based frequency distribution, and it can be determined by wet measurement using a laser diffraction particle size distribution measuring device. Examples of the laser diffraction particle size measuring device include the Mastersizer 3000 manufactured by Malvern. In the volume-based frequency distribution, the cumulative frequency can also be expressed based on any percentage other than the median (50%), and the preferred range can also be expressed as "the volume 40% diameter is 2.5 μm to the volume 60% diameter is 2.5 μm", etc. Also, in addition to the volume median diameter, it can be expressed as the weight median diameter, and furthermore, it can be expressed as any percentage.
[0060] Examples of the solid carrier include the following. Inorganic substances: minerals (natural silicates, marble, pumice, limestone, rare earth minerals, cryolite, activated clay, lime, activated carbon, talc, attapulgite, sodium montmorillonite, calcium montmorillonite, kaolinite, calcite, dolomite, diatomite, bentonite, zeolite, sepiolite, pyrophyllite, vermiculite, crystalline silica, amorphous silica, etc.), silicon dioxide, calcium sulfate, magnesium sulfate, barium sulfate, magnesium oxide, aluminum oxide, ammonium sulfate, ammonium phosphate, ammonium nitrate, calcium phosphate, sulfur, calcium carbonate, sodium bicarbonate, sodium carbonate, synthetic silicates, and ground products thereof; Organic substances: cereal powders (rice bran, rice flour, corn powder, wheat flour, etc.), saccharides (cellulose, starch, lactose, glucose, fructose, sucrose, etc.), plant-derived powders (nut shell pulverized products (coconut, walnut, peanut, etc. nut shell pulverized products), tree-derived powders (bark powder, sawdust, etc.), other plant pulverized products (tobacco stems, soybeans, cottonseed hulls, etc.)), lignin, wax, shells, urea, polyethylene, polypropylene, polyvinyl alcohol, polycarbonate, polyester, polyamide, polyurethane, polyvinyl chloride, polyvinyl acetate, ethylene-vinyl acetate copolymer, ethylene-methyl methacrylate copolymer, polyvinyl pyrrolidone-methacrylic acid copolymer, polyvinyl pyrrolidone-vinyl acetate copolymer, cellulose derivatives, phenolic resins, melamine resins, epoxy resins. Also, the above solid carrier can also be used as an adsorption carrier.
[0061] Examples of the liquid carrier include water, aliphatic hydrocarbons (hexane, 1-hexene, cyclohexane, octane, isooctane, 1-heptene, d-limonene, pinene, hexadecane, etc.). Aromatic hydrocarbons (alkylbenzenes (toluene, xylene, isopropylbenzene, p - diethylbenzene, etc.), derivatives of alkylbenzenes, alkylnaphthalenes, derivatives of alkylnaphthalenes, tetrahydronaphthalene, etc.), chlorinated hydrocarbons (monochloroethylene, dichloroethylene, trichloroethylene, tetrachloroethylene, dichloromethane, 1,1,1 - trichloroethane, 1,1,2 - trichloroethane, 1,2 - dichloropropane, etc.), ketones (cyclohexanone, acetone, 2 - heptanone, isophorone, mesityloxide, methyl isopentyl ketone, methyl ethyl ketone, methyl isobutyl ketone, acetophenone, diacetone alcohol, methylcyclohexanone, etc.), esters (fatty acid esters (ethyl acetate, butyl acetate, amyl acetate, isoamyl acetate, isobornyl acetate, hexyl acetate, heptyl acetate, octyl acetate, isopropyl myristate, methyl octanoate, methyl oleate, methyl laurate, dibutyl adipate, tributyl citrate, dibutyl phthalate, etc.), lactate esters (ethyl lactate, propyl lactate, etc.), carbonate esters (ethylene carbonate, propylene carbonate, butylene carbonate, diethyl carbonate, dibutyl carbonate, etc.), esterified polyols (glycerol acetate, glycol acetate, glycerol monoacetate, glycerol diacetate, glycerol triacetate, diethylene glycol abietate, dipropylene glycol dibenzoate, dipropylene glycol monomethyl ester, etc.), lactones (γ - butyrolactone, etc.), ethers (1,4 - dioxane, tetrahydrofuran, dipropylene glycol methyl ether, ethylene glycol methyl ether, propylene glycol methyl ether, etc.), amides (N - octyl - caprolactam, N - dodecyl - caprolactam, N,N - dimethylformamide, fatty acid dimethylamides (N,N - dimethylacetamide, N,N - dimethyldecanamide, N,N-dimethyloctanamide, etc.), alkylpyrrolidones (N-methylpyrrolidone, N-octyl-pyrrolidone, N-dodecyl-pyrrolidone, etc.), lactams (α-lactam, β-lactam, γ-lactam, δ-lactam, etc.), amines (octylamine, octylamine acetate, oleylamine, diethanolamine, laurylamine, etc.), alcohols (methanol, ethanol, butanol, propanol, isopropanol, butanol, amyl alcohol, hexanol, heptanol, octanol, 2-ethylhexanol, etc.), hexylene glycol, cyclohexanol, phenol, benzyl alcohol, methoxypropanol (1-methoxy-2-propanol), tetrahydrofurfuryl alcohol, furfuryl alcohol, polyethylene glycol, ethylene glycol, diethylene glycol, hexylene glycol, ethylene glycol methyl ether, diethylene glycol methyl ether, diethylene glycol butyl ether, triethylene glycol, propylene glycol methyl ether, dipropylene glycol, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol butyl ether, dipropylene glycol methyl ether, dipropylene glycol ether, dipropylene glycol monomethyl ether, glycerin, etc.), mineral oils (naphtha, petroleum ether, kerosene, diesel oil, paraffin, olefin, etc.), oils derived from animals and plants, plant-derived oils (palm oil, rapeseed oil, castor oil, coconut oil, soybean oil and its derivatives, etc.), animal-derived oils (sardine oil, saury oil, whale oil and its derivatives, etc.), dimethyl sulfoxide, silicone oil, acetonitrile, propanenitrile, acid anhydrides (acetic anhydride, etc.), triethyl phosphate, oleic acid, propionic acid, lactic acid, xylene sulfonic acid may be mentioned.,
[0062] Examples of the gaseous carrier include, for example, fluorocarbons, butane gas, LPG (liquefied petroleum gas), dimethyl ether, nitrogen, and carbon dioxide gas.
[0063] Examples of the anionic surfactant include carboxylic acids, sulfonic acids, sulfuric acid esters, and phosphoric acid esters, and specific examples thereof are as follows. Carboxylic acids: fatty acid salts (octanoate, decanoate, laurate, myristate, palmitate, stearate, behenate, oleate, polyoxyethylene alkyl ether carboxylates (laureth-3-carboxylate, α-(carboxymethyl)-ω-(dodecyloxy)poly(oxyethylene) salts, etc.), N-acyl sarcosine salts (N-lauroyl sarcosine salts, etc.), N-acyl glutamate salts (N-lauroyl glutamate salts, etc.), polycarboxylate salts (polyacrylate salts, polyvinyl acetate salts, comb-shaped polymers of polyacid salts, and their derivatives, etc.), Sulfonic acids: alkyl sulfonic acids and their salts (dodecyl sulfonate salts, etc.), alpha olefin sulfonate salts (alkene (C14-18) hydroxy sulfonate salts, alkapolyene (C12-20) hydroxy sulfonate salts, alkene (C14-18) hydroxy sulfonate salts, alkene (C12-20) hydroxy sulfonate salts, tetradecene-1-sulfonate salts, α-olefin (C14-16) sulfonate salts, etc.), alkyl benzene sulfonate salts (decyl benzene sulfonate salts, dodecyl benzene sulfonate salts, tridecyl benzene sulfonate salts, diphenyl sulfonate salts, etc.), alkyl naphthalene sulfonate salts (naphthalene sulfonate salts, 6-methyl-2-naphthalene sulfonate salts, dibutyl naphthalene sulfonate salts, 2,2'-dinaphthylmethane-6,6'-disulfonates, diisopropylnaphthalenesulfonates, triisopropylnaphthalenesulfonates, 1-isopropyl-2-naphthalenesulfonates, etc., sulfosuccinic acid, monoalkylsulfosuccinates, dialkylsulfosuccinates, (di(2-ethylhexyl)sulfosuccinate, etc.), N-methyl-N-acyltaurine salts (oleoylmethyltaurinate, etc.), ligninsulfonates, alkylphenolsulfonates, naphthalenesulfonate-formaldehyde condensates, benzimidazolesulfonates and their derivatives, as sulfate esters, alkyl sulfates (hexyl sulfate, heptyl sulfate, octyl sulfate, lauryl sulfate, lauryl sulfate diethanol salt, hexadecyl sulfate, octadecyl sulfate, etc.), polyoxyethylene alkyl ether sulfuric acid and its salts (laureth-3-sulfate, polyoxyethylene monotridecyl ether sulfuric acid, α-sulfo-ω-hydroxyalkyl (C6-10) ether poly(oxyethylene) salt, etc.), polyoxyethylene alkyl phenyl ether sulfates (poly(oxyethylene) 2-decylphenyl ether sulfate, poly(oxyethylene) 3-decylphenyl ether sulfate, α-sulfo-ω-[2,4-bis(1,1,3,3-tetramethylbutyl)phenoxy] poly(oxyethylene) salt, etc.), polyoxypropylene alkyl ether sulfates, lignosulfite waste liquor, and their derivatives; Phosphate esters: alkyl phosphates (propyl phosphate, hexadecyl phosphate, lauryl phosphate, dioctyl phosphate, etc.), polyoxyethylene alkyl ether phosphates (polyoxyethylene decyl phosphate ester, α-phosphono-ω-butoxypoly(oxyethylene), etc.), polyoxyethylene alkyl phenyl ether phosphates (α-(dinonylphenyl)-ω-hydroxypoly(oxyethylene) phosphate ester, α-(dodecylphenyl)-ω-hydroxypoly(oxyethylene) phosphate ester, α-(nonylphenyl)-ω-hydroxypoly(oxyethylene) phosphate ester, etc.), polyoxypropylene alkyl ether phosphates, and their derivatives.
[0064] Examples of cationic surfactants include amine salts and quaternary ammonium salts, and specifically, the following can be mentioned. Amine salts: alkylamine salts (monomethylamine salt, dimethylamine salt, trimethylamine salt, etc.), fatty acid amide amine salts (stearamidopropyldimethylamine, behenamidopropyldimethylamine, etc.), polyamine salts (polyvinylamine, polyethyleneimine, etc.), and derivatives thereof; Quaternary ammonium salts: lauryltrimethylammonium salt, cetyltrimethylammonium salt, dodecyltrimethylammonium salt, stearyltrimethylammonium salt, benzalkonium chloride, benzethonium chloride, benzylbis(2-chloroethyl)ethylammonium bromide salt.
[0065] Examples of amphoteric surfactants include betaine, alkyl betaine, alkyldimethyl betaine, imidazoline, taurine, alkyl taurine, dodecyldimethylammonioacetate, 4-carboxy-N,N,N-trimethyl-1-butanaminium, 1-carboxy-N,N,N-2-tetramethyl-1-propanaminium, N-alkyl(or alkenyl)(C12-18) glycine and its salts, N-dodecyl glycine and its salts, and derivatives thereof.
[0066] Examples of nonionic surfactants include alcohols, amides, amines, esters, ethers, ether esters, and carboxylic acids, and specifically, the following can be mentioned. Alcohols: aromatic alcohols (alkylphenols (allylphenol, octylphenol, nonylphenol, octylcresol, etc.), acylphenols, etc.), aliphatic alcohols (isotridecyl alcohol, oleyl alcohol, cetyl alcohol, etc.), polyhydric alcohols (polysaccharides, starch, starch derivatives, sucrose, alkyl polyglucoside, sorbitan, ethoxylated sorbitan, cellulose derivatives, gum arabic, etc.), synthetic polymers (polyvinyl alcohol, polyethylene glycol, etc.); Amides: alkanolamides (fatty acid alkanolamides (such as diethanol laurate), fatty acid glucamides (such as alkoxylated propylene oxide fatty acid glucamides), alkoxylated amides (such as polyoxyethylene oleic acid amide, polyoxyethylene stearic acid amide), synthetic polymers (such as polyvinylpyrrolidone), Amines: alkoxylated amines (such as polyoxyethylene oleylamine, α,α'-[(9-octadecenylimino)di-2,1-ethanediyl]bis(ω-hydroxy)polyoxyethylene); Esters: fatty acid esters (such as fatty acid esters of polyols, monoglycerides, phospholipids), esters derived from sugars (such as sucrose fatty acid esters (such as sucrose distearate), sorbitan fatty acid esters (such as sorbitan monooleate), glucose esters, cellulose esters), synthetic polymers (such as vinyl acetate copolymers, polymethacrylic acid, copolymers of methacrylic acid and methacrylic acid esters); Ethers: alcohol ethoxylates (such as aliphatic alcohol ethoxylates (such as tridecyl alcohol ethoxylate, isooctyl alcohol ethoxylate, lauryl alcohol ethoxylate, hexadecyl alcohol ethoxylate, stearyl alcohol ethoxylate)), alkylphenol ethoxylates (such as nonylphenol ethoxylate, tristyrylphenol ethoxylate, tributylphenol ethoxylate, octylphenol ethoxylate), arylalkylphenol ethoxylates, arylphenol ethoxylates (such as monobenzylbiphenol alcohol ethoxylate), alcohol propoxylates (such as aliphatic alcohol propoxylates, alkylphenol propoxylates, arylalkylphenol propoxylates), block polymers (such as block polymers of polyethylene oxide and polypropylene oxide, polyethylene oxide block polymers, polypropylene oxide block polymers, block polymers of alkanol, polyethylene oxide, and polypropylene oxide); Ether esters: polyoxyethylene fatty acid esters (such as polyoxyethylene castor oil ester, polyoxyethylene stearate, polyoxyethylene beef tallow fatty acid ester, etc.), polyoxyethylene sorbitan fatty acid esters (such as polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan stearate, etc.), polyoxyethylene fatty acid amine esters, polyoxyethylene rosin esters, polyoxypropylene fatty acid esters (such as polyoxypropylene castor oil ester, etc.), polyoxypropylene fatty acid amine esters; Carboxylic acids: undecafluorocaproic acid.
[0067] Other pharmaceutical adjuvants include, for example, thickeners, cryoprotectants / humectants, defoamers, antioxidants, pH adjusters, colorants, preservatives / bactericides, binders, fixing / spreading agents, lubricants, anti-caking agents, light stabilizers, fragrances, propellants, fertilizers, film agents, deodorants, plasticizers, desiccants / anti-humidity agents, fumigant auxiliaries, attractants, inclusion agents, efficacy enhancers, and specifically, the following are listed. Thickeners: polysaccharides (such as xanthan gum, cellulose ester, cellulose ether, carboxymethyl cellulose and its salts, dextrin, starch, guar gum, gum arabic, hydroxypropyl guar gum, tylose, carrageenan, etc.), clays (such as organic clay, organically modified clay, inorganic clay, inorganically modified clay, etc.), minerals (such as bentonite, attapulgite, silica, silicate, etc.), synthetic polymers (such as polycarboxylate, polyacrylic acid derivatives, polyvinylpyrrolidone, polyvinyl alcohol, etc.); Antifreezing agent and humectant: Alcohols (ethylene glycol, propylene glycol, dipropylene glycol, triethylene glycol, ethylene glycol methyl ether, propylene glycol methyl ether, dipropylene glycol methyl ether, ethylene glycol butyl ether, glycerin, polyethylene glycol, etc.), esters (dipropylene glycol dibenzoate, glycerol acetate, glycerol diacetate, glycerol triacetate, gamma-butyrolactone, etc.), ethers (1,4-dioxane, etc.), urea; Defoaming agent: Silicones (polysiloxane, diblock ethoxyl siloxane, triblock ethoxyl siloxane, etc.), alkyl sulfosuccinates, higher alcohols, higher alcohol derivatives, salts of fatty acids, fatty acid derivatives; Antioxidant: Phenols (2,6-di-t-butyl-p-cresol, 2,2'-methylenebis(4-methyl-6-t-butylphenol), etc.), amines (p,p'-dioctyldiphenylamine, N,N'-diphenyl-p-phenylenediamine, etc.), dibutylhydroxytoluene, butylhydroxyanisole, sodium erythorbate, sodium sulfite, potassium sulfite, potassium pyrosulfite, catechin, propyl gallate, sulfurs (didodecyl thiodipropionate, etc.), phosphates (trisnonylphenyl phosphite, etc.), vitamins (alpha tocopherol, L-ascorbic acid, sodium ascorbate, ascorbyl palmitate, etc.); pH adjuster: Sulfuric acid, nitric acid, hydrochloric acid, acetic acid, carbonic acid, oxalic acid, lactic acid, succinic acid, gluconic acid, citric acid, phosphoric acid, sorbic acid, and their salts, sodium hydrogen carbonate, sodium hydroxide, potassium hydroxide, calcium hydroxide, aluminum hydroxide, copper hydroxide, magnesium hydroxide; Colorants: Monoazo dyes (Pigment Red 48:1, Pigment Red 48:2, Pigment Red 53:1, Pigment Red 57:1, Pigment Red 112, Pigment Brown 25, C.l. Solvent Red 1, Pigment Yellow 1, Pigment Orange 5, Acid Red 14, Acid Yellow 23, etc.), Disazo dyes (Pigment Yellow 13, Pigment Orange 34, etc.), Phthalocyanines (Pigment Blue 15:1, Pigment Blue 15:2, Pigment Blue 15:3, Pigment Blue 15:4, Pigment Green 7, Pigment Green 36, etc.), Anthraquinone-based (Pigment Red 83, etc.), Dioxazine-based (Pigment Blue 80, etc.), Xanthene-based (Basic Violet 10 (Rhodamine B), Acid Red 51, Acid Red 52, etc.), Triarylmethane-based (Acid Blue 9, etc.), Pigment Orange 43, Iron oxide, Titanium, Titanium oxide, Zinc oxide, Zinc sulfide, Ferric hexacyano acid salt, Chrome vermilion, Lead yellow, Calcium carbonate, Barite powder, Aluminum powder; Antiseptics and bactericides: Phenols (orthophenylphenol, thymol, 3,5-dimethyl-4-chlorophenol, etc.), isothiazolinone derivatives (methylisothiazolinone (2-methyl-4-isothiazolin-3-one), chloromethylisothiazolinone (5-chloro-2-methyl-4-isothiazolin-3-one), octylisothiazolinone (2-n-octyl-4-isothiazolin-3-one), dichlorooctylisothiazolinone (4,5-dichloro-2-octyl-4-isothiazolin-3-one), benzisothiazolinone (1,2-benzisothiazolin-3-one), etc.), bronopol derivatives (bronopol (2-bromo-2-nitropropane-1,3-diol), etc.), benzyl alcohol hemiformal, isopropylmethylphenol, parabens (methylparaben, ethylparaben, propylparaben, isopropylparaben, butylparaben, isobutylparaben, heptylparaben, benzylparaben), imidazoles (thiabendazole), benzalkonium chloride, glyceryl caprylate, glyceryl caprate, glycerin fatty acid ester, sodium dehydroacetate, hinokitiol, acids (citric acid, phosphoric acid, sorbic acid, salicylic acid, benzoic acid, and their salts, etc.); Binders: Polysaccharides (xanthan gum, cellulose ester, cellulose ether, carboxymethyl cellulose, hydroxypropyl guar gum, guar gum, natural gum arabic, synthetic gum arabic, dextrin, starch, carrageenan, etc.), clays (organic clay, organically modified clay, inorganic clay, inorganically modified clay), minerals (bentonite), synthetic polymers (polycarboxylic acid or its salt, polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol, polyacrylic acid or its salt), waxes (vegetable oils, animal fats, and their derivatives, paraffin, olefin, etc.); Fixing agent and spreading agent: the surfactants and liquid carriers described above (esters (alkyl fatty acid esters, sorbitan fatty acid esters, ethoxylated fatty acid esters, ethoxysorbitan fatty acids, etc.), alcohols (ethoxylated aliphatic alcohols, ethoxysorbitan aliphatic alcohols, etc.), waxes (vegetable oils, animal oils, and their derivatives, paraffin, olefins, etc.), vegetable oils (alkylated vegetable oils, etc.), mineral oils (mineral oils, etc.), silicone emulsions, synthetic polymers (styrene-butadiene copolymers, methyl methacrylate-butadiene copolymers, polyacrylic acid or its salts, polyvinyl acetate, polyvinyl alcohol, polyvinyl pyrrolidone, polyethylene glycol, polypropylene glycol, etc.), natural polymers (xanthan gum, cellulose esters, cellulose ethers, carboxymethyl cellulose or its salts, dextrin, starch, guar gum, gum arabic, hydroxypropyl guar gum, tylose, etc.); Lubricant and lubricating agent: the alcohols, fatty acid esters, sucrose fatty acid esters, glycerin fatty acid esters, hydrocarbons, paraffin, ethylene wax, aliphatic amides, erucic acid amide, stearic acid amide, oleic acid amide, methylene bisstearic acid amide, ethylene bisstearic acid amide, metal soaps, lead stearate, zinc stearate, calcium stearate, magnesium stearate, mineral oil, vegetable oil, kerosene, diesel oil described in the liquid carriers and surfactants described above; Caking prevention agent: the solid carriers, liquid carriers, calcium phosphate, sodium phosphate, sodium carbonate, sodium silicate, calcium silicate, magnesium silicate, potassium aluminum silicate, silicon dioxide, talc, sodium aluminosilicate, calcium aluminosilicate, bentonite, stearic acid, dimethylpolysiloxane, powdered cellulose described above; Light stabilizers: titanium oxide, zinc oxide, activated carbon, carbon black, ethylhexyl methoxycinnamate, tert-butyl methoxydibenzoylmethane, hindered amines, ferulic acid, phenyl hydroxybenzoate, ethyl para-aminobenzoate, octyl salicylate, t-butylphenyl salicylate, 4-tert-octylphenyl salicylate, 2-ethylhexyl 2-cyano-3,3-diphenylacrylate (octocrylene), droxometrizole trisiloxane, 2,4,6-tris[4-(2-ethylhexyloxycarbonyl)anilino]-1,3,5-triazine (octyltriazine, TEAT), 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (MBP), 2-ethylhexyl dimethylaminobenzoate (EDB), homomenthyl salicylate (HS), phenylbenzimidazole sulfonic acid (PBS), hydroxymethoxybenzophenone sulfonic acid (oxybenzone 4, OXB4), sodium hydroxymethoxybenzophenone sulfonate (oxybenzone 5, OXB5), disodium dihydroxydimethoxybenzophenone disulfonate (oxybenzone 9, OXB9), tetrahydroxybenzophenone, dihydroxybenzophenone, dihydroxydimethoxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-ethylhexyl dimethoxybenzylidene dioxoimidazolidine propionate, 2,4-dihydroxybenzophenone, bis(2-methoxy-4-hydroxy-5-benzoylphenyl)methane; Fragrances: hydrocarbons, α-limonene, β-caryophyllene, alcohols, cis-3-hexenol, linalool, farnesol, β-phenylethyl alcohol, aldehydes, 2,6-nonadienal, citral, α-hexylcinnamic aldehyde, ketones, β-ionone, L-carvone, cyclopentadecanone, esters, linalyl acetate, benzyl benzoate, lactones, γ-undecalactone, phenols, eugenol, oxides, rose oxide, acetals, phenylacetaldehyde dimethyl acetal, α-pinene, β-pinene; Propellants: Liquefied petroleum gas, propane, normal butane, isobutane, normal pentane, isopentane and other aliphatic hydrocarbons with 3 to 5 carbon atoms, hydrofluoroolefins such as trans-1,3,3,3-tetrafluoroprop-1-ene and trans-2,3,3,3-tetrafluoroprop-1-ene, dimethyl ether, nitrogen gas, carbon dioxide gas, nitrous oxide gas, compressed air, and mixtures thereof; Fertilizers: Nitrogenous fertilizer components (urea, ammonium nitrate, ammonium magnesium nitrate, ammonium chloride, ammonium sulfate, ammonium phosphate, sodium nitrate, calcium nitrate, potassium nitrate, calcium cyanamide, formaldehyde-treated urea (UF), acetaldehyde-treated urea (CDU), isobutylaldehyde-treated urea (IBDU), guanylurea (GU)), phosphatic fertilizer components (superphosphate of lime, triple superphosphate of lime, fused phosphate, humic acid phosphate, calcined phosphate, double calcined phosphate, magnesium superphosphate, ammonium polyphosphate, potassium metaphosphate, calcium metaphosphate, magnesium phosphate, ammonium sulfate phosphate, potassium ammonium phosphate nitrate, ammonium chloride phosphate, etc.), potassic fertilizer components (potassium chloride, potassium sulfate, potassium sodium sulfate, potassium magnesium sulfate, potassium bicarbonate, potassium phosphate, etc.), siliceous fertilizer components (calcium silicate, etc.), magnesium fertilizer components (magnesium sulfate, magnesium chloride, etc.), calcium fertilizer components (quicklime, slaked lime, calcium carbonate, etc.), manganese fertilizer components (manganese sulfate, magnesium manganese sulfate, manganese ore, etc.), boron fertilizer components (boric acid, borate, etc.), iron-containing fertilizer components (steel slag, etc.), and other fertilizer components (copper, cobalt, zinc, etc.); Film-forming agents: Natural rubber, synthetic rubber, resins (styrene-butadiene copolymer, polyacrylonitrile, polyester, polyamide, polyurethane, polyurea, polyether, rosin, melamine, etc.), waxes (vegetable oils, animal fats, and their derivatives, paraffin, olefin, etc.), polysaccharides (xanthan gum, cellulose ester, cellulose ether, carboxymethyl cellulose or its salts, dextrin, starch, guar gum, gum arabic, hydroxypropyl guar gum, tylose, starch xanthate, carrageenan, etc.), proteins (gelatin, etc.); Deodorants: Organic clay, organically modified clay, unmodified clay, zinc silicate, silica gel; Plasticizers: Triethyl phosphate, citrate ester, phthalate ester, adipate ester, sebacate ester, phosphate ester; Desiccants and moisture-proof agents: Silica gel, calcium chloride, quicklime, aluminum oxide, zeolite, allophane; Smoke agent auxiliaries: Nitrocellulose, potassium chlorate, calcium oxide, melamine, potassium nitrate, azodicarbonamide; Attractants: Starch, cellulose, dextrin, acetic acids, alcohols, yeast extract; Inclusion agents: Cyclodextrins, α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin; Potency enhancers: The liquid carriers and surfactants described above.
[0068] When formulating this compound or composition A into an aqueous suspension formulation or an oily suspension formulation, usually, a cryoprotectant and / or a preservative is added. Preferred cryoprotectants include ethylene glycol, propylene glycol, and glycerin. Preferred preservatives include isothiazolinone derivatives (e.g., 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, 2-n-octyl-4-isothiazolin-3-one), and Proxel (1,2-benzisothiazolin-3-one). Ethylene glycol (hereinafter referred to as EG), propylene glycol (hereinafter referred to as PG), glycerin (hereinafter referred to as GL), 2-methyl-4-isothiazolin-3-one (hereinafter referred to as MIT), 5-chloro-2-methyl-4-isothiazolin-3-one (hereinafter referred to as CMIT), 2-n-octyl-4-isothiazolin-3-one (hereinafter referred to as OIT), 4,5-dichloro-2-octyl-4-isothiazolin-3-one (hereinafter referred to as DCOIT), 1,2-benzisothiazolin-3-one (hereinafter referred to as BIT), and 2-bromo-2-nitropropane-1,3-diol (hereinafter referred to as BNPD), which are used as cryoprotectants and preservatives, are commercially available.
[0069] Examples of the combination of this compound or composition A with the above-mentioned antifreeze or preservative are described below. SX + EG, SX + PG, SX + GL, SX + MIT, SX + CMIT, SX + OIT, SX + DCOIT, SX + BIT, SX + BNPD, Composition A + EG, Composition A + PG, Composition A + GL, Composition A + MIT, Composition A + CMIT, Composition A + OIT, Composition A + DCOIT, Composition A + BIT, Composition A + BNPD.
[0070] The weight ratio of this compound or composition A to the above-mentioned antifreeze or preservative is in the range of 1:0.0001 to 1:100. For example, the ranges of 1:0.0001 to 1:1, 1:0.005 to 1:0.01, 1:0.15 to 1:0.35, and 1:0.125 to 1:0.25 can be mentioned. Specific weight ratios include 1:0.0001, 1:0.0002, 1:0.0003, 1:0.0004, 1:0.0005, 1:0.0006, 1:0.0007, 1:0.0008, 1:0.0009, 1:0.001, 1:0.002, 1:0.003, 1:0.004, 1:0.005, 1:0.006, 1:0.007, 1:0.008, 1:0.009, 1:0.01, 1:0.02, 1:0.03, 1:0.04, 1:0.05, 1:0.06, 1:0.07, 1:0.08, 1:0.09, 1:0.1, 1:0.125, 1:0.15, 1:0.2, 1:0.25, 1:0.3, 1:0.4, 1:0.5, 1:0.6, 1:0.7, 1:0.8, 1:0.9, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:20, 1:30, 1:40, 1:50, 1:60, 1:70, 1:80, 1:90, 1:100. The above weight ratios can also be expressed approximately. Approximately means plus or minus 10%. For example, "approximately 1:2" means 1:1.8 to 1:2.2.
[0071] Examples of the combination of this compound or composition A with the above-mentioned antifreeze and preservative are described below. SX + EG + MIT, SX + EG + CMIT, SX + EG + OIT, SX + EG + DCOIT, SX + EG + BIT, SX + EG + BNPD, SX + PG + MIT, SX + PG + CMIT, SX + PG + OIT, SX + PG + DCOIT, SX + PG + BIT, SX + PG + BNPD, SX + GL + MIT, SX + GL + CMIT, SX + GL + OIT, SX + GL + DCOIT, SX + GL + BIT, SX + GL + BNPD, Composition A + EG + MIT, Composition A + EG + CMIT, Composition A + EG + OIT, Composition A + EG + DCOIT, Composition A + EG + BIT, Composition A + EG + BNPD, Composition A + PG + MIT, Composition A + PG + CMIT, Composition A + PG + OIT, Composition A + PG + DCOIT, Composition A + PG + BIT, Composition A + PG + BNPD, Composition A + GL + MIT, Composition A + GL + CMIT, Composition A + GL + OIT, Composition A + GL + DCOIT, Composition A + GL + BIT, Composition A + GL + BNPD. When combining the present compound or Composition A with the above-mentioned antifreezing agent and preservative, the mixing ratios of the present compound or Composition A with the antifreezing agent and of the present compound or Composition A with the preservative can be used within the same ranges as those described above.
[0072] In the case of granules or fine granules, a colorant can also be added to make it easier to confirm the granules or fine granules during or after application. Also, when applying Composition B to plant seeds or vegetative reproductive organs, a colorant can be added to make it easier to confirm that the application has been made.
[0073] Examples of the base materials for the resin preparation include polyethylene, polypropylene, polyvinyl alcohol, polycarbonate, polyester, polyamide, polyurethane, polyvinyl chloride, polyvinyl acetate, ethylene-vinyl acetate copolymer, ethylene-methyl methacrylate copolymer, polyvinyl pyrrolidone-methacrylic acid copolymer, polyvinyl pyrrolidone-vinyl acetate copolymer, cellulose derivatives, phenol resins, melamine resins, and epoxy resins. Plasticizers such as phthalic acid esters (dimethyl phthalate, dioctyl phthalate, etc.), adipic acid esters, and stearic acid may be added to these base materials as necessary. The resin preparation can be processed into various forms by molding as needed, for example, plate-like, film-like, tape-like, thread-like, net-like, cloth-like, string-like, block-like, etc. Specifically, it can be used in the form of animal collars, animal ear tags, clothing, protective hats, arm / leg covers, attracting strings, gardening supports, window screens, mosquito nets, etc. It can also be obtained by post-treating Composition B after molding the resin. Examples of the base materials for the bait preparation include cereal flour, vegetable oil, sugar, crystalline cellulose, etc. Further, antioxidants such as dibutylhydroxytoluene and nordihydroguaiaretic acid, preservatives such as dehydroacetic acid, anti-ingestion agents for children and pets such as ground pepper, and pest-attracting fragrances such as cheese fragrance, onion fragrance, and peanut oil may be added as necessary.
[0074] The effective amount of this compound, Composition A, or Composition B can be used to control harmful arthropods by applying it directly to the harmful arthropods or to the habitats where the harmful arthropods inhabit. Here, the habitats referred to include not only the places where the harmful arthropods inhabit but also the places where they are expected to inhabit. Specifically, examples include plants, plant cultivation areas, plant cultivation carriers, indoor and outdoor areas of buildings, building materials, foods, daily necessities, woods, vehicles, animal bodies, etc.
[0075] In the present invention, plants include the whole plant and specific parts of the plant. Examples of the specific parts of the plant include stems and leaves, flowers, spikes, fruits, trunks, branches, crowns, seeds, vegetative reproductive organs, and seedlings.
[0076] The vegetative reproductive organs refer to those parts among the roots, stems, leaves, etc. of plants that have the ability to grow when the part is separated from the main body and placed in the soil. Examples of vegetative reproductive organs include, for example, tuberous roots, creeping roots, bulbs, corms (or solid bulbs), tubers, rhizomes, stolons, rhizophores, cane cuttings, propagules, and vine cuttings. Note that stolons are sometimes called runners, propagules are also called bulbils, and are divided into broad buds and bulbils. Vine cuttings refer to the shoots (a general term for leaves and stems) of sweet potatoes and yams, etc. Bulbs, corms, tubers, rhizomes, cane cuttings, rhizophores, or tuberous roots are collectively also called bulbs. The cultivation of potatoes begins by planting tubers in the soil, and the tubers used are generally called seed tubers.
[0077] Seedlings include seedlings and saplings.
[0078] Examples of the cultivation land for plants include, for example, agricultural lands such as fields, paddy fields, orchards, and non-agricultural lands such as lawns and forests.
[0079] The cultivation carrier of plants is a support for plants, and any material on which plants can grow is acceptable. Examples include, for example, soil, seedling mats, and water. Specific materials for soil and seedling mats include, for example, sand, pumice, vermiculite, diatomaceous earth, gel substances, polymer substances, rock wool, glass wool, wood chips, and bark.
[0080] Examples of buildings include, for example, houses, commercial facilities, stations, airports, hospitals, factories, offices, schools, accommodation facilities, waste treatment facilities, livestock houses, and warehouses. Also, examples of the indoor areas of buildings include, for example, closets, cupboards, chests of drawers, kitchen cabinets, toilets, bathrooms, storerooms, living rooms, bedrooms, and dining rooms.
[0081] Examples of the outdoor environment include, for example, the ground, outer walls, fences, ditches, spaces, water meters, water storage tanks, wells, puddles, rain barrels, rain gutters, septic tanks, old tires, reservoirs, rivers, waterways, forests, and lakes.
[0082] Examples of building materials include, for example, wood, concrete, bricks, plastics, glass, wallpaper, insulation materials, packing materials, pipes, electric cables, paints, and sealing materials.
[0083] Examples of foods include, for example, agricultural products (grains, fruits, spices, and products processed from these), livestock and fishery products (meat, fish, eggs, milk, and products processed from these). Also, examples of daily necessities include plant-derived products (cotton, paper, tobacco, and products processed from these), animal-derived products (skin, hair, wool, feathers, silk, and products processed from these), electrical appliances, and other products (furniture, stationery, toys, tableware).
[0084] Examples of wood include, for example, wood processed for construction (high-density wood, laminated wood, plywood, fiberboard, hardboard, MDF, insulation board, particle board, insulation hardboard, OSB, LSL, glued laminated timber, cross-laminated timber, flooring, composite flooring, etc.).
[0085] Examples of vehicles include, for example, bicycles, cars (private cars, buses, taxis, freight carriers, etc.), trains, airplanes, and ships.
[0086] Examples of animal bodies include, for example, livestock (cows, horses, pigs, sheep, goats, chickens, etc.) and small animals (dogs, cats, rats, mice, etc.).
[0087] When Composition B is used for controlling harmful arthropods in the agricultural field, its application rate can vary widely depending on the type of plant to be applied, the type and occurrence frequency of the harmful arthropods to be controlled, the formulation form, the application time, the application method, the application location, the weather conditions, etc. Usually, the application rate of the present compound or one kind of the present component is 1 to 10,000 g per hectare, preferably 5 to 5,000 g, more preferably 50 to 2,000 g (specifically, for example, 100 g, 200 g, 300 g, 500 g). When Composition B is formulated into an emulsion, wettable powder, flowable agent, etc., usually, it is diluted with water so that the concentration of the present compound or one kind of the present component is 0.01 to 10,000 ppm, preferably 0.1 to 5,000 ppm, more preferably 1 to 1,000 ppm (specifically, for example, 10 ppm, 100 ppm, 500 ppm) and then applied. When Composition B is formulated into a granule, powder, etc., usually, it is applied as it is.
[0088] These formulations and the aqueous dilution solutions of the formulations may be directly sprayed on the harmful arthropods or the plants to be protected from the harmful arthropods, or may be treated on the cultivation carrier to control the harmful arthropods occurring on the cultivation carrier.
[0089] In addition, Composition B, which is a resin formulation processed into a sheet or string shape, can also be treated by methods such as winding it around the plant, stretching it near the plant, or laying it on the cultivation carrier.
[0090] When Composition B is applied to a plant or the cultivation area of a plant, it is applied once or multiple times. The plant or the cultivation area of the plant may have harmful arthropods already occurring, or may be before the occurrence.
[0091] Examples of the treatment method of Composition B include foliar treatment, soil treatment, root treatment, shower treatment, mist spraying treatment, fumigation treatment, water surface treatment, hydroponic solution treatment, and seed treatment.
[0092] Examples of the foliar treatment include methods of treating Composition B on the surface of the foliage, trunk, fruit, flower, or ear. Examples of root treatment include, for example, a method of immersing roots in a chemical solution containing Composition B, and a method of attaching a solid preparation containing Composition B to the roots of a plant. Examples of soil treatment include, for example, soil spraying, soil mixing, and chemical solution irrigation of the soil. Also, examples of the location for soil treatment include, for example, planting holes, furrows, areas near planting holes, areas near furrows, the entire cultivation area in its entirety, the plant rhizosphere, between plants, under the tree trunk, main stem ridges, soil covering, seedling boxes, seedling trays, seedling beds, etc. Examples of the treatment timing include, for example, before sowing, at sowing, after sowing, the seedling raising period, before planting, at planting, and the growth period after planting, etc. Also, in the above soil treatment, Composition B may be treated on the plant simultaneously, and a paste fertilizer, liquid fertilizer, solid fertilizer, etc. containing Composition B may be applied to the soil. Also, it may be mixed with the irrigation liquid, for example, injection into irrigation equipment (irrigation tubes, irrigation pipes, sprinklers, etc.), mixing into the inter-row flooded liquid, mixing into the hydroponic solution, etc. Also, the irrigation liquid and the active ingredient may be mixed in advance, and for example, it can be treated using the above irrigation methods or other appropriate irrigation methods such as spraying and flooding. Examples of shower treatment include, for example, a method of showering a diluted solution of Composition B on fruits after harvest. Examples of mist spraying treatment include, for example, a method of atomizing a diluted solution of Composition B and scattering it into the air to adhere to the stems, leaves, and fruits of plants. Examples of fumigation treatment include, for example, a method of heating a solid preparation containing Composition B to make it smoky and suspending it in the air to adhere to the stems, leaves, and fruits of plants. Examples of water surface treatment include, for example, a method of spraying a chemical solution containing Composition B or a solid preparation containing Composition B on a paddy field in a flooded state. Examples of hydroponic solution treatment include, for example, a method of mixing or incorporating a chemical solution containing Composition B or a solid preparation containing Composition B into the hydroponic solution (hydroponic solution mixing treatment, hydroponic solution incorporation treatment, etc.).
[0093] Seed treatment Seed treatment means treating the seeds or vegetative reproductive organs with Composition B. Examples of the seed treatment method of Composition B include, for example, spraying treatment in which a suspension of Composition B is atomized and sprayed onto the seed surface or the surface of the vegetative reproductive organ, smearing treatment in which Composition B is applied to the seeds or vegetative reproductive organs, dipping treatment in which the seeds are immersed in the chemical solution of Composition B for a certain period of time, and methods of coating the seeds or vegetative reproductive organs with a carrier containing Composition B (film coating treatment, pellet coating treatment, etc.). As the above-mentioned vegetative reproductive organs, especially seed tubers are mentioned. When treating the seeds or vegetative reproductive organs with Composition A, Composition A can be treated as one formulation on the seeds or vegetative reproductive organs, or Composition A can be treated on the seeds or vegetative reproductive organs in multiple times as a plurality of different formulations. Examples of the method of treating Composition A in multiple times as a plurality of different formulations include, for example, treating with a formulation containing only this compound as the active ingredient, air-drying the seeds or vegetative reproductive organs, and then treating with a formulation containing this ingredient; and treating with a formulation containing this compound and this ingredient as the active ingredient, air-drying the seeds or vegetative reproductive organs, and then treating with a formulation containing this ingredient other than the treated this ingredient. After seed treatment, the active ingredient may completely or partially cover the seeds or vegetative reproductive organs, may be scattered on its surface, and / or may be present inside it. When treating, it is preferably to use a composition containing this ingredient having at least one bactericidal activity selected particularly from group (b) and group (j) among Composition B. At this time, this compound may be treated on commercially available seeds or vegetative reproductive organs treated with this ingredient having at least one bactericidal activity selected from group (b) and group (j). When treating Composition B on the seeds or vegetative reproductive organs, manganese, copper, zinc, etc. may also be treated simultaneously. When treating Composition B on seeds, the application amount of Composition B is usually 0.001 to 100 g, preferably 0.02 to 50 g per 1 kg of seeds or vegetative reproductive organs, and the application amount per one active ingredient contained in Composition B is usually 0.001 to 100 g, preferably 0.01 to 50 g, more preferably 0.1 to 10 g per 1 kg of seeds or vegetative reproductive organs. Specifically, for example, the following treatment amounts are included. 0.05 g of the active ingredient per 1 kg of seeds or vegetative reproductive organs; 0.5 g of the active ingredient per 1 kg of seeds or vegetative reproductive organs; 5 g of the active ingredient per 1 kg of seeds or vegetative reproductive organs. The seeds or vegetative reproductive organs holding the present compound or Composition A in the present invention mean those in a state where the present compound or Composition A is attached to the surface of the seeds or vegetative reproductive organs. The seeds or vegetative reproductive organs holding the above-mentioned present compound or Composition A may have materials other than the present compound or Composition A attached thereto before or after the present compound or Composition A is attached to the seeds or vegetative reproductive organs. In addition, when Composition A is attached to the surface of seeds or vegetative reproductive organs in the form of a layer, the layer may consist of one layer or a plurality of layers. When consisting of a plurality of layers, each layer may be a layer containing one or more active ingredients, or may consist of a layer containing one or more active ingredients and a layer not containing an active ingredient. The seeds or vegetative reproductive organs holding the present compound or Composition A can be obtained, for example, by applying a composition B containing the present compound or Composition A to the seeds or vegetative reproductive organs by the above-mentioned seed treatment method.
[0094] As seed treatment formulations, generally, DS, ES, FS, LS, WS, CF, GF, SS, etc. are known, but CS, EG, EW, GW, ME, OD, OF, SC, SE, SG, SL, SP, ST, WG, WP, WT, ZC, ZE, ZW, etc. can also be used. These formulations contain one present compound or the present component in a weight ratio of 0.01 to 70%, preferably 0.1 to 50%. When treating these formulations on seeds or vegetative reproductive organs, they may be used as they are, or may be diluted with water for use. When treating the formulation diluted with water on seeds or vegetative reproductive organs, it can be arbitrarily diluted according to the content of the active ingredient in the formulation and the amount of the active ingredient to be retained on the seeds or vegetative reproductive organs, but generally, it is often diluted 2 to 1000 times for use. When treating seeds, the seeds before sowing or the seeds after germination may be treated. When the compound or composition A is used for seed treatment, adjuvants such as colorants and binders may be mixed during formulation, or may be further mixed when the formulated composition B is used for seed treatment. The colorant facilitates the confirmation of whether the composition B has been applied to each individual seed or vegetative reproductive organ. The binder can also be added to improve the adhesion of the active ingredient to the seed or vegetative reproductive organ. Examples of specific colorants and binders are shown below. Colorants: For example, monoazo dyes (Pigment Red 48:1, Pigment Red 48:2, Pigment Red 53:1, Pigment Red 57:1, Pigment Red 112, Pigment Brown 25, C.l. Solvent Red 1, Pigment Yellow 1, Pigment Orange 5, Acid Red 14, Acid Yellow 23, etc.), disazo dyes (Pigment Yellow 13, Pigment Orange 34, etc.), phthalocyanines (Pigment Blue 15:1, Pigment Blue 15:2, Pigment Blue 15:3, Pigment Blue 15:4, Pigment Green 7, Pigment Green 36, etc.), anthraquinone-based dyes (Pigment Red 83, etc.), dioxazine-based dyes (Pigment Blue 80, etc.), xanthene-based dyes (Basic Violet 10 (Rhodamine B), Acid Red 51, Acid Red 52, etc.), triarylmethane-based dyes (Acid Blue 9, etc.), Pigment Orange 43, iron oxide, titanium, titanium oxide, zinc oxide, zinc sulfide, ferric hexacyanoate, chrome vermilion, lead yellow, calcium carbonate, barite powder, aluminum powder; Binder: Polysaccharides (xanthan gum, cellulose ester, cellulose ether, carboxymethyl cellulose, hydroxypropyl guar gum, guar gum, natural gum arabic, synthetic gum arabic, dextrin, starch, carrageenan, etc.), clays (organic clay, organically modified clay, inorganic clay, inorganically modified clay, etc.), minerals (bentonite, etc.), synthetic polymers (polycarboxylic acid or its salt, polyvinyl pyrrolidone, polyvinyl acetate, polyvinyl alcohol, polyacrylic acid or its salt, styrene-butadiene copolymer, methyl methacrylate-butadiene copolymer, polyacrylic acid or its salt, polyvinyl acetate, polyvinyl alcohol, polyvinyl pyrrolidone, polyethylene glycol, polypropylene glycol, etc.), waxes (vegetable oils, animal fats, and their derivatives, paraffin, olefin, etc.). When treating the seed or vegetative reproductive organ with Composition B, an adjuvant may be mixed with Composition B as needed. The seeds or vegetative reproductive organs treated with Composition B are sown or planted in the field by a normal method.
[0095] The present compound and the present component may be applied to plants or the soil in which plants are cultivated, or the place where harmful arthropods occur, separately at the same time, or the present compound and the present component may be applied to plants or a cultivation carrier, or the place where harmful arthropods occur, separately at different times. Specifically, for example, either the present compound or the present component may be applied to the cultivation carrier (e.g., soil, etc.) before or after planting the seeds or vegetative reproductive organs treated with the other one in the cultivation carrier.
[0096] Composition B can be applied to plants in which one or more components selected from the present components have been pre-treated on seeds and the cultivation carrier of the plants. Examples of the application methods include foliar treatment, soil treatment, root treatment, shower treatment, mist spraying treatment, fumigation treatment, water surface treatment, and hydroponic solution treatment.
[0097] Examples of the seed treatment agent pre-treated on soybeans in advance include the following. STANDAK-TOP 500FS (Fipronil / Pyraclostrobin / Thiophanate-m), DERMACOR 625FS (Chlorantraniliprole), CRUISER 350FS (Thiamethoxam), CROPSTAR 600FS (Imidacloprid / Thiodicarb), FORTENZA 600FS (Cyantraniliprole), S-UNSPEC-INS-WHEAT, NEMAT 300WP (Verticillium), FIPRONIL-ALTA 250FS (Fipronil), MAXIM-ADVANCED 195FS (Fludioxonil / Metalaxyl-M / Thiabendazole), SHELTER 250SC (Fipronil), MAXIM-XL 035FS (Fludioxonil / Metalaxyl-M), DEROSAL Plus(Carbendazim / Thirum), Vitavax - THIRAM(Carboxin / Thiram).
[0098] Examples of seed treatment agents pre-treated on corn seeds include the following. PONCHO-VOTIVO 601EC (Bacillus-firmus / Clothianidin), ACCELERON-IC-609 600EC (Clothianidin), CRUISER 600FS (Thiamethoxam), ACCELERON-D-342 480FS (Prothioconazole), PONCHO 600FS (Clothianidin), MAXIM-QUATTRO 382.5FS (Azoxystrobin / Fludioxonil / Metalaxyl-M / Thiabendazole), AVICTA-COMPLETE-CORN-250 280FS, Abamectin / Azoxystrobin / Fludioxonil / Metalaxyl-M / Thiabendazole / Thiamethoxam), AVICTA-COMPLETE-CORN-500 423FS, (Abamectin / Azoxystrobin / Fludioxonil / Metalaxyl-M / Thiabendazole / Thiamethoxam), LUMIVIA 625FS (Chlorantraniliprole), ACCELERON-D-281 480FS (Fluoxastrobin), ACCELERON-DC-309 312FS (Metalaxyl).
[0099] Examples of the seed potato treatment agents pre-treated on potatoes include the following. Maxim 4FS (fludioxonil), Maxim MZ (fludioxonil + Mancozeb), Cruiser MAXX Vibrance Potato (fludioxonil + difenoconazole + Sedaxane + Thiamethoxam), Emesto Silver (penflufen + prothioconazole), MonCoatMZ (flutolanil + Mancozeb), Moncut (flutolanil), Elatus (azoxystrobin + benzovindiflupyr), Quadris (azoxystrobin), Serenade ASO (Bacillus subtillis), DoubleNickel LC (Bacillus amyloliquefaciens), Attackin (streptomycin, thiophanate M), Frontside (fluazinam), Basidac (mepronil), Moncut (flutolanil), Rovral (iprovalicarb), Moncut (flutolanil), Benlate (benomyl).
[0100] When applying Composition B, spraying equipment can be used. Examples of the equipment used for application include, for example, hand sprayers, power sprayers, puncture sprayers, manned aircraft (such as manned helicopters), unmanned aircraft (such as radio-controlled helicopters, drones), tractors, planters, etc. Also, it may be applied by hand without using spraying equipment.
[0101] When using a sprayer when applying Composition B, the spraying pressure is not particularly limited, but is usually 30 - 120 PSI, preferably 40 - 80 PSI. Here, the spraying pressure is the setting before introduction to the nozzle.
[0102] When using a sprayer when applying Composition B, the spray nozzle is not particularly limited, and examples include flat spray nozzles, conical nozzles, rotary nozzles, hollow cone nozzles, deflector nozzles, linear nozzles, etc.
[0103] When Composition B is applied in the form of a solution, the pH and hardness of the solution are not particularly limited, but the pH is generally in the range of 5 to 9, and the hardness is generally in the range of 0 to 500 in terms of American hardness. The time period for applying Composition B is not particularly limited, but generally, the range from 5 am to 9 pm is common. Also, the photosynthetic photon flux density at the grass canopy level at the location where Composition B is applied is usually 10 to 2500 micromol / m 2 / s. The weather conditions when applying Composition B are not particularly limited, but the air temperature is usually 0 to 30°C, preferably 10 to 20°C, the soil temperature is usually 0 to 30°C, preferably 10 to 20°C, the relative humidity is 50 to 90%, preferably 40 to 80%, and the wind speed is 0 to 2 MPH.
[0104] When spraying Composition B, it is usually carried out by spraying a spraying liquid obtained by mixing Composition B with water. When preparing the spraying liquid, it can be directly diluted in the water of the spraying liquid volume, or after mixing Composition B with a small amount of water and making it uniform, water is added to prepare a specified liquid volume. Although the spraying liquid volume is not particularly limited, it is usually in the range of 5 to 5000 L / ha, preferably 20 to 1000 L / ha, more preferably 140 to 300 L / ha. Specific spraying liquid volumes include 10 L / ha, 30 L / ha, 50 L / ha, 70 L / ha, 90 L / ha, 100 L / ha, 120 L / ha, 150 L / ha, 180 L / ha, 200 L / ha, 250 L / ha, 300 L / ha, 400 L / ha, 500 L / ha, 700 L / ha, 900 L / ha, 2000 L / ha, 4000 L / ha.
[0105] When spraying Composition B using a manned aircraft or an unmanned aircraft, although the spraying height is not particularly limited, it is usually 0.5 to 30 m, preferably 1 to 10 m.
[0106] When carrying out foliar treatment, soil treatment, root treatment, shower treatment, fumigation treatment, water surface treatment, seed treatment and hydroponic solution treatment of Composition B, Composition B and an adjuvant may be mixed. They may be premixed (premix) before formulation or mixed immediately before use (tank mix). The type of adjuvant is not particularly limited, but examples include COC (Crop oil concentrate) derived from mineral oil, MSO (methylated seed oil) derived from vegetable oil, alcohol-based solvents, nonionic surfactants, anionic surfactants, cationic surfactants, silicone-based, nitrogen fertilizers, etc. and mixtures thereof. Specifically, AgriDex (registered trademark), Induce (registered trademark), Grammin S (registered trademark), Genamin T 200BM (registered trademark), Silwet L77 (registered trademark), Nimbus (registered trademark), Assist (registered trademark), Aureo (registered trademark), Iharol Gold (registered trademark), BreakThru (registered trademark), SundanceII (registered trademark), Lutensol A8 (registered trademark), NP-7 (registered trademark), Triton (registered trademark), Nufilm (registered trademark), Emulgator NP7 (registered trademark), Emulad (registered trademark), TRITON X 45 (registered trademark), AGRAL 90 (registered trademark), AGROTIN (registered trademark), ARPON (registered trademark), EnSpray N (registered trademark), BANOLE (registered trademark), Ochima (registered trademark), Agris (registered trademark), AMS (Ammonium Sulfate), UAN (Urea Ammonium Nitrate), AdGreen (registered trademark), Mees (trademark), Rumba (registered trademark), Strides (registered trademark), Partner, Orix (registered trademark), Penetrator, etc. Furthermore, a drift reducer such as Intact (registered trademark) may be mixed. The weight ratio of Composition B to the above adjuvant or drift reducer is not particularly limited, but for example, a range of 1:100 to 100:1 can be mentioned.
[0107] Composition B can be mixed or used in combination with fertilizers. When mixing, it may be premixed (premix) before formulation or mixed immediately before application (tank mix). Fertilizers include substances containing various elements such as nitrogen (N), phosphorus (P), potassium (K), silicon, magnesium, calcium, manganese, boron, iron, copper, zinc, sulfur, molybdenum, cobalt, etc. Substances containing nitrogen, phosphorus, and potassium include, for example, urea, ammonium nitrate (ammonium nitrate), ammonium chloride (ammonium chloride), ammonium sulfate (ammonium sulfate), sodium nitrate, magnesium nitrate, nitric acid, anhydrous ammonia, urea ammonium nitrate, calcium nitrate, calcium cyanamide, phosphoric acid, superphosphate of lime, triple superphosphate of lime, potassium sulfate, potassium chloride, potassium silicate, potassium hydroxide, potassium nitrate, potassium phosphate, MAP (monoammonium phosphate), DAP (diammonium phosphate). The form of the fertilizer can be any of granular, powdered, lumpy, liquid, etc., and fertilizers in various forms can be used. The places of application include, for example, the soil surface, in the soil, and on plants. The equipment used for application includes, for example, hand sprayers, power sprayers, puncture sprayers, manned aircraft (such as manned helicopters), unmanned aircraft (such as radio-controlled helicopters, drones), tractors, planters, broadcasters, seeders, etc. Also, it may be applied by hand without using spraying equipment. As a specific application method, for example, at the time of sowing or planting of plants, or during the period before or after sowing or planting (e.g., within ±0, 1, 2, 3, 4, 5 days of sowing), a method of treating the composition B and the fertilizer together near the seeds, vegetative reproductive organs, or seedlings can be mentioned (sometimes also called in-furrow application). The fertilizer applied at the time of sowing or planting of plants, or during the period before or after sowing or planting, may be a solid fertilizer and / or a liquid fertilizer. For example, fertilizers having an N:P:K ratio are included (sometimes called starter fertilizer, pop-up fertilizer, etc.). The composition B and the fertilizer may be mixed immediately before application and used, or may be applied separately and simultaneously. The application location is not particularly limited as long as it is near the seeds, vegetative reproductive organs, or seedlings, but it may be the planting furrow of the seeds, vegetative reproductive organs, or seedlings, or a location several inches away from the planting furrow of the seeds, vegetative reproductive organs, or seedlings. For example, a location 2 inches horizontally and 2 inches vertically from the planting furrow of the seeds, vegetative reproductive organs, or seedlings can be mentioned (sometimes called 2-by2 band). Examples of crops include corn, soybean, sugarcane, potato, wheat, barley, rye, oat, and rice. The ratio of the weight of one active ingredient contained in the composition B to the total weight of NPK contained in the fertilizer is not particularly limited, but for example, a range of 1:1 to 1:10000 can be mentioned.
[0108] The composition B can be applied by spot treatment. Spot treatment is a concept opposite to uniformly treating the composition B, and means a treatment of selectively spraying the composition B at a location where harmful arthropods have occurred or where there is a risk of harmful arthropods occurring. "Treating a location" means treating a plant or soil where harmful arthropods have occurred or are likely to occur, but preferably when treating a plant. When treating a plant, it also includes treating only the individuals in the plant population where harmful arthropods have occurred or are likely to occur, and treating the parts in the plant individuals where harmful arthropods have occurred or are likely to occur. Even when Composition B is somewhat sprayed in a place where no harmful arthropods are generated due to scattering, evaporation, etc., or in a place where there is no risk of harmful arthropods being generated, if it is not a uniform surface treatment, it is included in spot treatment. Also, in a continuous cultivation area, it is not considered spot treatment only when all places where harmful arthropods are generated or where there is a risk of harmful arthropods being generated are selectively treated. That is, even when a part of the cultivation area is subjected to surface treatment, or when a part of the place where harmful arthropods are generated or where there is a risk of harmful arthropods being generated is not treated with Composition B, if there is a place that has been spot-treated in a continuous cultivation area, it is included in spot treatment.
[0109] As a method of spot treatment, specific examples are given below. In a plant cultivation area, while a sprayer walks, or while a sprayer rides on a device that travels on the ground or an aircraft, spot treatment may be performed by visually spraying Composition B using a handheld nozzle or a robot arm nozzle. Furthermore, a place where harmful arthropods have occurred or may occur may be mapped in advance, and spot treatment may be performed by spraying Composition B based on the map information. In spraying based on map information, in addition to the above method, during the travel or flight of the sprayer, the nozzles on the boom or the robot arm nozzles may be automatically or manually opened and closed based on the position information of the sprayer (obtained by GPS, etc.) and the map information, etc., to perform spot treatment. The map information may be created based on image information taken by a manned or unmanned flying object, etc., or may be created visually by an observer walking on the ground, an observer riding on a device traveling on the ground, or an observer riding on an aircraft. Furthermore, a traveling or flying sprayer may be equipped with a function to detect a place where harmful arthropods are generated or may be generated, and spot treatment may be performed by the boom, robot arm, etc. while performing real-time mapping.
[0110] Places where harmful arthropods are present can be recognized not only by visual recognition by sprayers or observers but also in image analysis using visible light, and may also be recognized in image analysis using specific wavelengths in hyperspectral images. The image analysis may be in a form where the screen is visually inspected to recognize the presence of harmful arthropods, or image recognition using artificial intelligence may also be used (for example, Optimum Co., Ltd. press release on December 26, 2017). These images may be taken by manned or unmanned flying objects, etc., or may be taken by a photographer walking on the ground, a photographer riding in a device traveling on the ground, or a photographer riding in an aircraft. Places where there is a risk of harmful arthropods occurring may be estimated based on the fact that the harmful arthropods have occurred patchily during the past cultivation period of the crop, or may be estimated from the distribution of harmful arthropods in the soil. The distribution of harmful arthropods in the soil may be investigated by soil sampling or may be estimated by remote sensing. Also, the fact that harmful arthropods are lurking in plants may be sensed and estimated by image analysis. Such technology is known as a form of emerging agriculture called precision agriculture, smart agriculture, or digital agriculture, and the non-uniform spraying pattern generated by the spot treatment may also be called VRA (Variable Rate Application) in the terminology of such emerging agriculture.
[0111] As a method for spot-treating Composition B, there are a method of spraying it on the soil at the location where harmful arthropods have occurred or on the soil at a location where harmful arthropods may occur (soil treatment), and a method of spraying Composition B on plants where harmful arthropods have occurred or on plants where harmful arthropods may occur (foliar treatment). Spraying is usually carried out using a spraying solution prepared by mixing Composition B with water. Although the amount of the spraying solution is not particularly limited, usually, within the section to be spot-treated, it is 50 to 1000 L / ha, preferably 100 to 500 L / ha, more preferably 140 to 300 L / ha. The ratio of the area to be spot-treated in the cultivated area of plants (the ratio of the area where Composition B is sprayed to the entire area of a continuous cultivated area) is usually 1 to 99%, preferably 10 to 80%. Specifically, 20%, 30%, 40%, 50%, 60%, and 70% etc. may be mentioned. When spot-treating, the treatment amount of Composition B, as the treatment amount of one active ingredient within the section to be spot-treated, is 5 to 2000 g per ha, preferably 50 to 1500 g per ha, more preferably 200 to 1000 g per ha, and even more preferably 400 to 700 g per ha. In addition, when carrying out spot treatment, an adjuvant or a drift reducing agent may be mixed. The types of the adjuvant or the drift reducing agent are not particularly limited, but for example, those mentioned above may be included. The pH and hardness of the spraying solution are not particularly limited, but the pH is usually in the range of 5 to 9, and the hardness is usually in the range of 0 to 500 in American hardness. The time zone for carrying out spot treatment is not particularly limited, but it is usually in the range from 5 am to 9 pm, and the photosynthetic photon flux density at the grass canopy level at the location where spot treatment is carried out is usually 10 to 2500 micromol / m 2 / second. On the other hand, spot treatment can also be carried out at night using the map information and the position information. The spraying pressure when carrying out spot treatment is not particularly limited, but it is usually 30 to 120 PSI, preferably 40 to 80 PSI. Here, the spraying pressure is the setting before introduction to the nozzle. The weather conditions for performing spot treatment are not particularly limited, but the air temperature is usually 0 to 30°C, preferably 10 to 20°C, the ground temperature is usually 0 to 30°C, preferably 10 to 20°C, the relative humidity is 50 to 90%, preferably 40 to 80%, and the wind speed is 0 to 2 MPH.
[0112] The treatment method of Composition B is more specifically hole treatment (hole spraying, hole treatment soil mixing), base treatment (base spraying, base soil mixing, base perfusion, post-seedling base treatment), furrow treatment (furrow spraying, furrow soil mixing), ridging treatment (ridging spraying, ridging soil mixing, in-season ridging spraying), ridging treatment at sowing (ridging spraying at sowing, ridging soil mixing at sowing), overall treatment (overall soil spraying, overall soil mixing), side ridging treatment, water surface treatment (water surface application, post-flooding water surface application), other soil spraying treatments (in-season granule foliar spraying, spraying under the canopy or around the main trunk, soil surface spraying, soil surface mixing, seed hole spraying, surface spraying on the ridge, inter-plant spraying), other perfusion treatments (soil perfusion, seedling perfusion, chemical injection treatment, ground-level perfusion, chemical drip irrigation, chemigation), seedling box treatment (seedling box spraying, seedling box perfusion, seedling box chemical flooding), seedling tray treatment (seedling tray spraying, seedling tray perfusion, seedling tray chemical flooding), seedbed treatment (seedbed spraying, seedbed perfusion, water-seedling substitute seedbed spraying, seedling dipping), bed soil mixing treatment (bed soil mixing, pre-sowing bed soil mixing, spraying before covering soil at sowing, spraying after covering soil at sowing, covering soil mixing), and other treatments (earthing-up mixing, hoeing in, topsoil mixing, rainwater collection part soil mixing, planting position treatment, granule inflorescence spraying, paste fertilizer mixing, hydroponic solution mixing, hydroponic solution incorporation), etc.
[0113] The application of this compound or composition A may also be able to reduce the mycotoxin content in the harvested materials and the foods and feeds prepared therefrom. The mechanism of the mycotoxin reduction effect is not limited, but is exerted, for example, by direct or indirect actions on mycotoxin-producing fungi. Examples of direct actions include bactericidal effects on mycotoxin-producing fungi and inhibitory effects on mycotoxin biosynthesis. Examples of indirect actions include effects on the microbiota (microbiome) such as the abundance ratio of mycotoxin-producing fungi to non-producing fungi, and reduction of fungal infections by suppressing damage caused by harmful arthropods. Also, examples of mycotoxins include, but are not particularly limited to, the following. Deoxynivalenol (DON), nivalenol, fusarenone X, 15-Ac-DON, 3-Ac-DON, T2- and HT2-toxins, neosolaniol, fumonisins, zearalenone, moniliformin, fusarins, diacetoxyscirpenol (DAS), beauvericin, enniatins, fusaroproliferin, fusarenol, ochratoxin, patulin, sterigmatocystin, martrin, citrinin, rugulosin, rubratoxin, citreoviridin, cyclochlorotine, luteoskyrin, lolitrem B, slaframine, sporidesmin, ergot alkaloids (e.g., lysergic acid, ergotamine, ergometrine), aflatoxins, and cyclopiazonic acid. These mycotoxins can be produced, for example, by the following fungi. Species of the genus Fusarium, such as F. acuminatum, F. asiaticum, F. avenaceum, F. crookwellense, F. culmorum, F. graminearum (Gibberella zeae), F. equiseti, F. fujikoroi, F. moniliforme, F. musarum, F. oxysporum, F. proliferatum, F. poae, F. pseudograminearum, F. sambucinum, F. scirpi, F. semitectum, F. solani, F. sporotrichoides, F. langsethiae, F. subglutinans, F. tricinctum, F. verticillioides, etc.; species of the genus Aspergillus, such as A. flavus, A. parasiticus, A. nomius, A. ochraceus, A. carbonarius, A. clavatus, A. terreus, A. versicolor; species of the genus Penicillium, such as P. verrucosum, P. viridicatum, P. citrinum, P. expansum, P. claviforme, P. roqueforti, species of the genus Claviceps, such as C. purpurea, C. fusiformis, C.fusiformis), C. paspali, C. africana, etc.; species of the genus Stachybotrys; species of the genus Slafractonia, such as S. leguminicola, etc.; species of the genus Neotyphodium, such as, N. lolii, etc.; species of the genus Pithomyces, such as P. chartarum.
[0114] By applying the present compound or composition A, depending on the plant species or variety, their growth locations and growth conditions (soil, climate, growth period, nutrients), it is possible to improve the seedling establishment rate of plants, improve plant growth, improve tolerance to abiotic stresses (for example, improve tolerance or tolerance to high or low temperatures, tolerance to drought, waterlogging, over-wetting or salts contained in water or soil, improve tolerance to osmotic stress, improve tolerance to drought stress, improve tolerance to ozone exposure, improve tolerance to ultraviolet stress, improve tolerance to wind stress, and improve tolerance to sunlight stress), improve flowering ability, improve ease of harvesting, promote ripening, increase yield, increase the number, size or weight of seeds or fruits, improve the green color of leaves, maintain the green color of leaves for a long period, increase the number of healthy leaves, suppress the progress of aging, reduce lodging of plants, flower earlier, increase the number of flowerings or fruit set, increase the fruit set rate, improve the quality of the harvested product and / or increase nutritional value (for example, increase the sugar content in fruits, improve gluten strength, optimize protein content, optimize oil content, improve nutritional value), improve the storage stability of the harvested product and / or improve processability. More specifically, as for improving plant growth, it includes promoting stem elongation, promoting stem thickening, promoting an increase in the number of leaves or total leaf area, increasing healthy leaves, and promoting stem branching (for example, promoting an increase in the number of stem branches), promoting lateral root formation (for example, increasing the number of lateral roots, etc.), increasing the auxin production sites in the roots (main roots or lateral roots), promoting root elongation, improving root spreading, and promoting root thickening. Also, it may be possible to improve tolerance to nutritional stress caused by a deficiency of any of the 17 essential nutrients (essential elements) for plant growth.
[0115] When using Composition B against harmful arthropods in non-agricultural fields, its application rate can be widely varied depending on the type and occurrence frequency of the harmful arthropods to be controlled, formulation form, application time, application method, application location, weather conditions, etc. As specific application methods, for example, when applying to a building, it includes treating the walls, floors, underfloors, ceilings, roofs, attics, doors, windows, screens, etc. of the building, treating the indoor space of the building, and installing bait agents and resin formulations. When applying outdoors, examples include treatment of the ground, outer walls, fences, ditches, soil injection into the area under the floor or ground, treatment of spaces, and treatment of granular or resin formulations in water. When applying to building materials, examples of methods include kneading or coating the building materials. When applying to food and daily necessities, examples include treatment of emulsion, wettable powder, flowable agent, oil agent, etc. on the walls, floor, and ceiling of the place where the food and daily necessities are stored, treatment of fumigant, vaporizer, aerosol, etc. in the space, installation of poison bait agent, resin formulation, etc., kneading, coating, treatment of powder or emulsion, etc. of the daily necessities. When applying to wood, examples include coating, spraying, dipping, impregnating, injecting, mixing during wood processing, and mixing with adhesives to the wood. When applying to vehicles, examples include treatment of the space and walls inside the vehicle and installation of poison bait agent and resin formulation. When applying to animals, methods of oral administration by mixing into capsule agents, chewables, syrups, tablets, powders, and feed / drinking water, methods of administration by suppositories and injections (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), methods of spraying, coating, or dripping liquid agents such as spot-on agents, pour-on agents, shampoo agents, lotion agents, paste agents, etc., or methods of processing resin formulations into collars, ear tags, bracelets, and clothing for wearing.
[0116] When using Composition B for controlling harmful arthropods in non-agricultural fields, the application rate when treating the surface is the amount of one active ingredient per 1 m 2 of the treated area, usually 0.01 - 1000 mg, preferably 10 - 500 mg, more preferably 20 - 400 mg (specifically, for example, 25 mg, 50 mg, 400 mg). The application rate when treating the space is the amount per 1 m 3The amount of one active ingredient per unit is usually 0.01 to 500 mg. When treating in water, the application rate is the amount of one active ingredient per liter of water volume, usually 0.001 to 1000 mg, more preferably 0.01 to 100 mg. When treating animals, the application rate is usually the amount of one active ingredient per kilogram of the animal's body weight, usually in the range of 0.01 to 1000 mg. When Composition B is formulated into an emulsion, wettable powder, flowable agent, etc., it is usually diluted with water so that the concentration of one active ingredient becomes 0.1 to 10000 ppm and then applied. When formulated into an oil agent, etc., it is applied as it is or usually diluted with kerosene, light oil, etc. so that the concentration of one active ingredient becomes 0.1 to 10000 ppm and then applied. Granules, powders, aerosol agents, fumigants, fumes, poisonous baits, resin preparations, etc. are applied as they are. Also, incense sticks are ignited and applied. Electric mosquito mats, liquid mosquito repellent preparations, fan-type mosquito repellent preparations, ultrasonic vibration-type preparations, electrostatic spray-type preparations, etc. are usually applied using a power source or battery.
[0117] Composition B can be used for the purpose of suppressing the biting behavior and discomfort behavior of harmful arthropods such as mosquitoes and flies by applying it to the body surfaces of humans and animals. It can also be used for the purpose of suppressing the generation and growth of flies, etc. that occur in excrement by mixing it into feed and orally administering it to animals.
[0118] In addition, Composition B can also be used for preventing the spread of infectious diseases (such as malaria, dengue fever, West Nile fever, yellow fever, Zika fever, filariasis, onchocerciasis, leishmaniasis, Chagas disease, African sleeping sickness, etc.) transmitted by harmful arthropods. Specific application methods include treating the inner walls of houses with Composition B (Indoor Residual Spray; IRS), treating outdoor spaces (Space spray), using mosquito nets treated with Composition B (Long lasting insecticidal net), wallpapers, poisonous baits, egg-laying traps, trapping traps, space repellent devices, using automatic dissemination devices, treating water tanks, reservoirs, streams, etc. with Composition B (measures against the source of pests, Larvicide), etc.
[0119] By applying the present compound or composition A, depending on the plant species or variety, their growth location and growth conditions (soil, climate, growth period, nutrients), it is possible to improve the seedling establishment rate of plants, improve plant growth, improve tolerance to abiotic stresses (for example, improve tolerance or tolerance to high or low temperatures, tolerance to drought, waterlogging, over-wetting or salts contained in water or soil, improve tolerance to osmotic stress, improve tolerance to dry stress, improve tolerance to ozone exposure, improve tolerance to ultraviolet stress, improve tolerance to wind stress, and improve tolerance to sunlight stress), improve flowering ability, improve ease of harvesting, promote maturation, increase yield, increase the number, size or weight of seeds or fruits, improve leaf greenness, maintain leaf greenness for a long period, increase the number of healthy leaves, suppress the progress of aging, reduce plant lodging, promote earlier flowering, increase the number of flowerings or fruit settings, increase the fruiting rate, improve the quality and / or increase the nutritional value of the harvested product (for example, increase the sugar content in fruits, improve gluten strength, optimize protein content, optimize oil content, improve nutritional value), improve the storage stability and / or processability of the harvested product, etc. More specifically, as for the improvement of plant growth, it includes promoting stem elongation, promoting stem thickening, promoting an increase in the number of leaves or total leaf area, increasing the number of healthy leaves, and promoting stem branching (for example, promoting an increase in the number of stem branches), promoting lateral root formation (for example, increasing the number of lateral roots, etc.), increasing the auxin production sites in the roots (main roots or lateral roots), promoting root elongation, improving root spreading, and promoting root thickening. Also, it may be possible to improve tolerance to nutritional stress caused by a deficiency of any of the 17 essential nutrients (essential elements) for plant growth.
[0120] When using composition B for controlling harmful arthropods in non-agricultural fields, its application rate can be varied widely depending on the type and occurrence frequency of the harmful arthropods to be controlled, formulation form, application time, application method, application location, weather conditions, etc. As specific application methods, for example, when applying to a building, it includes treating the walls, floors, underfloors, ceilings, roofs, attics, doors, windows, screen doors, etc. of the building, treating the indoor space of the building, and installing bait agents and resin formulations. When applying outdoors, examples include treatment of the ground, outer walls, fences, ditches, soil injection under floors or on the ground, etc., treatment of spaces, and treatment of granular or resin formulations in water. When applying to building materials, examples of methods include kneading or coating on building materials. When applying to foods and daily necessities, examples include treatment of emulsions, wettable powders, flowables, oils, etc. on the walls, floors, and ceilings of the places where the foods and daily necessities are stored, treatment of fumigants, fumigants, smoke agents, etc. in spaces, installation of poison baits, resin formulations, etc., kneading, coating, treatment with powders, emulsions, etc. of the daily necessities. When applying to wood, examples include coating, spraying, dipping, impregnating, injecting, mixing during wood processing, and mixing with adhesives on the wood. When applying to vehicles, examples include treatment of the space and walls inside the vehicle and installation of poison baits and resin formulations. When applying to animals, methods of oral administration by mixing into capsule agents, chewables, syrups, tablets, powders, and feed / drinking water, etc., methods of administration by suppositories and injections (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), methods of spraying, coating, or dripping liquid agents such as spot-on agents, pour-on agents, shampoo agents, lotion agents, paste agents, etc., or methods of processing resin formulations into collars, ear tags, bracelets, and clothing, etc. and wearing them.
[0121] When using Composition B for controlling harmful arthropods in non-agricultural fields, the application rate when treating the surface is the amount of one active ingredient per 1 m 2 of the treated area, usually 0.01 - 1000 mg, preferably 10 - 500 mg, more preferably 20 - 400 mg (specifically, for example, 25 mg, 50 mg, 400 mg), and the application rate when treating the space is the amount per 1 m 3The amount of one active ingredient is usually 0.01 to 500 mg. When treating in water, the application rate is the amount of one active ingredient per 1 L of water volume, usually 0.001 to 1000 mg, more preferably 0.01 to 100 mg. When treating animals, the application rate is usually in the range of 0.01 to 1000 mg per 1 kg of the animal's body weight. When Composition B is formulated into an emulsion, wettable powder, flowable agent, etc., it is usually diluted with water so that the concentration of one active ingredient becomes 0.1 to 10000 ppm and then applied. When formulated into an oil agent, etc., it is applied as it is or usually diluted with kerosene, light oil, etc. so that the concentration of one active ingredient becomes 0.1 to 10000 ppm and then applied. Granules, powders, aerosol agents, fumigants, vaporizers, poison baits, resin preparations, etc. are applied as they are. Also, incense sticks are ignited and applied. Electric mosquito mats, liquid mosquito repellent preparations, fan-type mosquito repellent preparations, ultrasonic vibration-type preparations, electrostatic spray-type preparations, etc. are usually applied using a power source or battery.
[0122] Examples of plants for which Composition B can be used include the following. Crops; Maize (dent, flint, soft, pop, waxy, sweet, field corn), Rice (long grain, short grain, medium grain, japonica, tropical japonica, indica, javanica, paddy, upland rice, floating rice, direct seeding, transplanting, glutinous rice), Wheat (bread wheat (hard, soft, medium, red wheat, white wheat), durum wheat, spelt wheat, club wheat, each winter wheat type, spring wheat type), Barley (two-row barley (= beer barley), six-row barley, naked barley, glutinous barley, each winter barley type, spring barley type), Rye (winter rye type, spring rye type), Triticale (winter triticale type, spring triticale type), Oats (winter oats type, spring oats type), Sorghum, Cotton (upland cotton, pima cotton), Soybeans (fully mature seed harvest varieties, edamame varieties, green forage varieties, each indeterminate growth type, determinate growth type, semi-determinate growth type), Peanuts, Cowpeas, Lima beans, Adzuki beans, Broad beans, Mung beans, Black soybeans, Scarlet runner beans, Winged beans, Moth beans, tepary beans, Field beans, Peas, Chickpeas, Lentils, Lupins, Kidney beans, Alfalfa, Potatoes (tetraploid, diploid, true seed varieties), Buckwheat, Sugar beets (for sugar production, for feed, root vegetables, leaf vegetables, for fuel), Rapeseed (winter rapeseed type, spring rapeseed type), Canola (winter canola type, spring canola type), Sunflowers (for oil extraction, for food, for ornamental purposes), Sugarcane, Tobacco, Tea plants, Mulberry, etc. Vegetables; Solanaceae vegetables (Eggplants, Tomatoes, Bell peppers, Chili peppers, Sweet peppers, etc.), Cucurbitaceae vegetables (Cucumbers, Pumpkins, Zucchini, Watermelons, Melons, Squashes, etc.), Brassicaceae vegetables (Radishes, Turnips, Horseradish, Kohlrabi, Chinese cabbages, Cabbages, Mustard greens, Broccoli, Cauliflower, etc.), Asteraceae vegetables (Gobo, Shungiku, Artichokes, Lettuces, etc.), Alliaceae vegetables (Leeks, Onions, Garlic, Asparagus, etc.), Apiaceae vegetables (Carrots, Parsleys, Celery, American lovage, etc.), Chenopodiaceae vegetables (Spinach, Lamb's quarters, etc.), Lamiaceae vegetables (Perilla, Mints, Basils, Lavenders, etc.), Strawberries, Sweet potatoes, Yams, Taro, etc. Fruit trees; pome fruits (apple, pear, Japanese pear, Chinese pear, quince, medlar, etc.), stone fruits (peach, plum, nectarine, Japanese apricot, apricot, cherry, prune, etc.), citrus fruits (satsuma mandarin, orange, lemon, lime, grapefruit, etc.), nuts (chestnut, walnut, hazelnut, almond, pistachio, cashew nut, macadamia nut, etc.), berry fruits (blueberry, cranberry, blackberry, raspberry, etc.), grape, oyster mushroom, fig, olive, loquat, banana, coffee, date palm, coconut palm, etc. Ornamental plants; flowering trees and shrubs, street trees (Paulownia, Catalpa, Japanese Judas tree, eucalyptus, ginkgo, lilac, maple, oak, poplar, magnolia, wisteria, plane tree, zelkova, elm, beech, spruce, fir, pine, hemlock, Japanese yew), flowers, foliage plants, grasses.
[0123] The plants described above are not limited as long as they are generally cultivated varieties.
[0124] Examples of corn varieties include the following. P30F53, P30F53RR, P30F53YHV, DKB390, DKB390IPRO3, DKC62-08, DKC35-88RIB RR2 BT, P7958AM RR2 LL BT, NK1120-3122 RR+GLU+ECB+CRW, P9608AM LL RR2 CRW ECB, Golden Bantam
[0125] Examples of wheat varieties include the following. PAKITO; KWS Zyatt; Skyfall; Crusoe; RGT Illustrious; KWS Extrase; KWS Extase; KWS Siskin; LG Detroit; KWS Lili; KWS Firefly; KWS Barrel; Elicit; KWS Basset; Zulu; LGSkyscraper; RGT Saki; LG Spotlight; KWS Jackal; Elation; Bennington; LG Sundance; LG Motown; Leeds; Viscount; Revelation; SY Insitor; KWS Kinetic; Gleam; RGT Gravity; KWS Kerrin; Shabras; Graham; KWS Crispin; Theodore; Dunston; Costello
[0126] Examples of wheat varieties include, for example, the following. Electrum; Craft; SY Venture; KWS Hawking; LG Mountain; KWS Gimlet; Jordan; LG Flynn; KWS Orwell; Valerie; Surge; KWS Creswell; KWS Tower; KWS Glacier; California; KWS Cassia; Belmont; SY Kingsbarn; SY Baracooda; Bazooka; Belfry; KWS Astaire; Funky; Libra; SY Splendor; Firefoxx; Cosmopolitan; SY Tungsten; LG Diablo; Laureate; RGT Planet; RGT Asteroid; Iconic; KWS Sassy; Sienna; Propino; Fairing; Concerto; Fairway; Prospect
[0127] Examples of soybean varieties include, for example, the following. 5G8015 RR IPRO; ANTA 82 PR; AS 3797 IPRO; BMX POTENCIA RR; BRS 8170IPRO; BRS 8280 RR; DM 6583 IPRO; M 5947 IPRO; M 6410 IPRO; M 8644 IPRO; M8372 IPRO; M9114PR; MONSOY 5947 IPRO; MONSOY 7730 IPRO; MSOY 8372 IPRO; NA 5909 RG; NS 5445 IPRO; NS 5909 PR; NS 5969 IPRO; NS 6700 IPRO; ST 797; TMG 1180 RR; TMG 1188 RR NS 4823 RR; NS 5445 IPRO; NA 5909 RR; NS 6209 RR; NS 6601 IPRO; NS 6823 RR; NS 6906 IPRO; NS 7000 IPRO; NS 7200 RR; NS 7227 RR; NS 7300 IPRO; NS 7474 IPRO; NS 7505 IPRO; NS 7709 IPRO; NS 8270 IPRO; NS 8393 IPRO RR; NS 5106 IPRO; NS 5727 IPRO; NS 5959 IPRO; NS 6390; NS 6700 IPRO; NS 6828; NS 6909 IPRO - Centro; NS 7000 IPRO -SUL; NS 7202 IPRO; NS 7237 IPRO; NA 7337 RR; NS 7490 RR; NS 7667 IPRO; NS 7901; NS 8338 IPRO; NS 8490 IPRO; NS 5160 IPRO; NA 5909- RG IPRO; NS 6006 IPRO; NS 6535 IPRO; NS 6767 RR; NS 6906 IPRO - Centro; NS 6909 IPRO - Sul; NS 7070 IPRO; NS 7209 IPRO; NS 7300 IPRO - Centro; NS 7338 IPRO; NS 7497 RR; NS 7670 RR ; NS 8094 RR; NS 8383 RR; Syn 15600 IPRO;Syn 16861 IPRO; Syn 1059 RR; Syn 1163 RR; Syn 1258 RR; Syn 1281 RR; Syn 1683 IPRO; Syn 1785 IPRO; Syn 1687 IPRO; Syn 13610 IPRO; Syn 15640 IPRO; Syn 15630 IPRO; Syn 1562 IPRO; Syn 1561 IPRO; Syn 1366 IPRO; CZ 15B64 IPRO; CZ15B70 IPRO; CZ 15B92 IPRO; CZ 26B05 IPRO; CZ 26B10 IPRO; CZ 26B77 IPRO; CZ 7022 IPRO; CZ 26B42 IPRO; CZ 26B36 IPRO; CZ 26B42 IPRO; CZ 26B77 IPRO; TEC 7022 IPRO; CZ 37B22 IPRO; CZ 37B43 IPRO; CZ 47B90 IPRO; CZ 58B28 IPRO; CZ 48B32 IPRO; CZ 58B61 IPRO; W 791 RR; W 842 RR; CZ 58B61 IPRO; BS 1511 IPRO; BS 1543 IPRO; ST 575 IPRO; BS 1580 IPRO; ST 592 IPRO; BS 2590 IPRO; BS 2606 IPRO- SUL; ST 644 IPRO; BSIRGA 1642 IPRO; TEC 6702 IPRO; BS 1691 IPRO; TEC 7849 IPRO; TECIRGA 6070 RR; BS 1519 LL; BS 2606 IPRO -CERRADO; TEC 6702 IPRO -CERRADO; TEC 7849 IPRO-CERRADO; ST 721 IPRO; TEC 7578 IPRO; ST 777 IPRO; ST 797 IPRO; ST 804 IPRO; ST 830 IPRO; ST 845 IPRO; W 787 IPRO; W 799 RR; ST 815 RR; ST 820 RR; ST 860 RR; ST 920 RR; W 870; BRASMAX COMPACTA IPRO; BRASMAX FIBRA IPRO BRASMAX ZEUS IPRO; BRASMAX DELTA IPRO; BRASMAX RAIO IPRO; BRASMAX ICONE IPRO; BRASMAX LANCA IPRO; BRASMAX GARRA IPRO; BRASMAX PONTA IPRO BRASMAX VALENTE RR; BRASMAX POTENCIA RR; BRASMAX TORNADO RR; BRASMAX ALVO RR; BRASMAX ATIVA RR; BRASMAX VELOZ RR; BRASMAX VELOZ RR; BRASMAX VORAZ IPRO; BRASMAX EXTREMA IPRO; BRASMAX UNICA IPRO; BRASMAX DOMINIO IPRO; BRASMAX FOCO IPRO; BRASMAX EXTREMA IPRO; BRASMAX EXTRA IPRO; BRASMAX CERTA IPRO; BRASMAX POWER IPRO; BRASMAX ULTRA IPRO; BRASMAX FLX IPRO; BRASMAX BONUS; BRASMAX PONTA IPRO; BRASMAX OPUS IPRO; BRASMAX DESAFIO RR; M5705IPRO; MS5838IPRO; M5892IPRO; M8644IPRO; M5917IPRO; M5947IPRO; M6210IPRO; M7739IPRO; M8349IPRO; M8372IPRO; M6410IPRO; M7110IPRO; M7198IPRO; M8210IPRO; M8808IPRO; 95R51; 95Y52; 97R22IPRO; 99R03; P98Y70; 95R90IPRO; 95Y72; 98Y21IPRO; 99R09; 95R95IPRO; 96Y90; 98Y30; P98C81; BG4290; BG4786; CD2720 IPRO; CD2728 IPRO; CD2820 IPRO; CD2851 IPRO; CD2857 RR; DS5916 IPRO; 5D6215 IPRO; 5D634 RR; 5G8015 IPRO; DS6017 IPRO; DS7417 IRPO; B5860 IPRO; BG4781 IPRO; DS6217 IPRO; TMG2375 IPRO; TMG2379 IPRO; TMG7058 IPRO; TMG2165 IPRO; TMG2165 IPRO; TMG4377 IPRO; TMG1180 RR;TMG7063IPRO; TMG7062 IPRO; TMG7067 IPRO; TMG4182; TMG4182; TMG7262 RR; TMG2185 IPRO; TMG7061 IPRO; TMG2381 IPRO; TMG2383 IPRO; TMG1288 RR; TMG2181 IPRO; TMG1188 RR; TMG2378 IPRO; TMG2173 IPRO; TMG4185; TMG 7363 RR: TMG7260 IPRO; TMG133 RR; TMG132 RR; ANTA82; TMG1182 RR; TMG2182 IPRO; TMG7161 RR; TMG2183 IPRO; TMG2286 IPRO; K8620 IPRO; RK5519 RR; M6210 IPRO; RK6719 IPRO; RK6316 IPRO; RK7518 IPRO; RK8115 IPRO; RK8317 IPRO; RK5813 RR; RK6813 RR; BRS 1001IPRO; BRS 1074IPRO; BRS 6970IPRO; BRS 7570IPRO; BRS 9383IPRO; BRS 1003IPRO; BRS 706IPRO; BRS 7170IPRO; BRS 7780IPRO; BRS 1007IPRO; BRS 713IPRO; BRS 7270IPRO; BRS 7180IPRO; BRS1010IPRO; BRS 729IPRO; BRS 7470IPRO; BRS 9180IPRO; BRS 279RR; BRS 360RR; BRS 413RR; BRS 8890RR; BRSGO 8151RR; BRSMG 850GRR; BRS 378RR; BRSMG 760SRR; BRS 9090RR; BRS 740SRR; BRS FAVORITA RR; BRS 333RR; BRS 388RR; BRS 7950RR; BRS 9280RR; BRSMG 750SRR; BRS Sambaiba RR; BRS 359RR; BRS 399RR; BRS 8160RR; BRS 7460RR; BRSMG 811CRR; BRS VALIOSA RR; BRS 232; BRS 283; BRS 257;BRS 284; BRS 317 ; BRS 361; BRSMG 800A; BRSGO 8360; BRSGO LUZIANIA; BRS Petala; BRSMG 790A; BRSMG 7525; MG / BR 46 (Conquista); BRS 8381; BRS 217 (Flora); BRS 252 (Serena); BRSMG 810C; BRSMG 68 (Vencedora); BRSGO 7960; BRS 8480; BRSGO Chapadoes; BRS Raimunda; BRS313 (TIETA); BRS Corisco; BRS Barreiras; BRS 314 (Gabriela); BRS Tracaja; BRS Perola
[0128] The above-mentioned plant varieties are not particularly limited as long as they are commonly cultivated varieties.
[0129] The above-mentioned plants may be plants that can be produced by natural cross-breeding, plants that can be generated by mutation, F1 hybrid plants, or transgenic plants (also referred to as genetically modified plants). These plants generally have characteristics such as resistance to herbicides, accumulation of toxic substances against pests (also referred to as pest resistance), suppression of susceptibility to diseases (also referred to as disease resistance), increase in yield potential, improvement in resistance to biotic and abiotic stress factors, modification of the quality of the product (e.g., increase or decrease in the content of specific components, change in composition, improvement in shelf life or processability), modification of the harvest time (e.g., extremely early maturing, early maturing, mid-season maturing, late maturing, extremely late maturing), etc.
[0130] An F1 hybrid plant is a first-generation hybrid obtained by crossing two different varieties of strains, and generally has the characteristic of heterosis, having traits superior to those of either parent. A transgenic plant is a plant that has been given characteristics that cannot be easily obtained by cross-breeding, mutagenesis, or natural recombination in the natural environment by introducing foreign genes from other organisms such as microorganisms.
[0131] Examples of techniques for creating the above plants include conventional breeding techniques; genetic recombination techniques; genomic breeding techniques; new breeding techniques; and genome editing techniques. Conventional breeding techniques are techniques for obtaining plants with desirable properties through, for example, mutation or crossing. Genetic recombination techniques are techniques for conferring new properties on an organism by extracting a target gene (DNA) from a certain organism (e.g., a microorganism) and introducing it into the genome of another target organism, or techniques such as antisense techniques or RNA interference techniques for conferring new or improved characteristics by silencing other genes present in plants. Genomic breeding techniques are techniques for improving the efficiency of breeding using genomic information, and include DNA marker (also called genomic marker or gene marker) breeding techniques and genomic selection. For example, DNA marker breeding is a method of selecting progeny with a target useful trait gene from a large number of cross progeny using a DNA marker, which is a DNA sequence that serves as a landmark for the location of a specific useful trait gene on the genome. By analyzing cross progeny using DNA markers at the seedling stage, it has the characteristic of being able to effectively shorten the time required for breeding. Genomic selection is a method that creates a prediction formula from previously obtained phenotypic and genomic information and predicts traits without evaluating the phenotype from the prediction formula and genomic information, and it is a technology that can contribute to improving the efficiency of breeding. New breeding techniques are a general term for variety improvement (breeding) techniques that combine molecular biological methods. For example, there are techniques such as cisgenesis / intragenesis, oligonucleotide-directed mutagenesis, RNA-dependent DNA methylation, genome editing, grafting onto GM rootstocks or scions, reverse breeding, agroinfiltration, seed production technology (Seed Production Technology, SPT), etc. Genome editing technology is a technology that converts genetic information in a sequence-specific manner, and it is possible to perform deletions of base sequences, substitutions of amino acid sequences, introduction of foreign genes, etc. As tools, for example, zinc-finger nucleases (Zinc-Finger Nucleases, ZFN, ZFNs), TALEN, CRISPR / Cas9, CRISPR / Cpf1, and meganuclease, which can perform sequence-specific DNA cleavage, can be mentioned. In addition, there are sequence-specific genome modification techniques such as CAS9 nickase and Target-AID created by modifying the above-mentioned tools.
[0132] Examples of the above-mentioned plants include, for example, plants listed in the registration database (GM APPROVAL DATABASE) of genetically modified crops on the electronic information site (http: / / www.isaaa.org / ) of the INTERNATINAL SERVICE for the ACQUISITION of AGRI-BIOTECH APPLICATIONS (ISAAA). More specifically, for example, herbicide-tolerant plants, pest-resistant plants, disease-resistant plants, plants with modified product quality (e.g., increase or decrease in component content, change in composition, improvement in shelf life or processability), plants with modified fertility traits, abiotic stress-tolerant plants, or plants with modified traits related to growth and yield.
[0133] Examples of herbicide - tolerant plants are given below. Mechanisms of tolerance to herbicides include, for example, reducing the affinity between the herbicide and its target; rapid metabolism (decomposition, modification, etc.) of the herbicide by the expression of an enzyme that inactivates the herbicide; inhibition of the uptake of the herbicide into the plant body; and inhibition of the translocation of the herbicide within the plant body.
[0134] Plants imparted with herbicide tolerance by genetic recombination technology include, for example, plants imparted with tolerance to protoporphyrinogen oxidase (hereinafter abbreviated as PPO) herbicides such as flumioxazin; 4 - hydroxyphenylpyruvate dioxygenase (hereinafter abbreviated as HPPD) inhibitors such as isoxaflutole and mesotrione; acetolactate synthase (hereinafter abbreviated as ALS) inhibitors such as imidazolinone - based herbicides like imazetapyr and sulfonylurea - based herbicides like thifensulfuron - methyl; 5 - enolpyruvylshikimate - 3 - phosphate synthase (hereinafter abbreviated as EPSPS) inhibitors such as glyphosate; glutamine synthetase inhibitors such as glufosinate; auxin - type herbicides such as 2,4 - D and dicamba; and oxynil - type herbicides such as bromoxynil. Preferred herbicide - tolerant transgenic plants are wheat such as Triticum aestivum, Hordeum vulgare, Secale cereale, Avena sativa, canola, sorghum, soybean, maize, cotton, rice, rapeseed, sugar beet, sugarcane, grape, lentil, sunflower, alfalfa, pome fruits, stone fruits, coffee, tea, strawberry, miscanthus, tomato, potato, cucumber, lettuce and other vegetables. More preferably, they are wheat such as Triticum aestivum, Hordeum vulgare, Secale cereale, Avena sativa, soybean, maize, rice, grape, tomato, potato, and pome fruits. Specific herbicide - tolerant plants are shown below. Glyphosate-tolerant plants: Obtained by introducing one or more of the following genes: a glyphosate-tolerant EPSPS gene (CP4 epsps) derived from Agrobacterium tumefaciens strain CP4, a glyphosate N-acetyltransferase gene (gat4601 or gat4621) modified from a glyphosate N-acetyltransferase gene derived from Bacillus licheniformis, a glyphosate oxidase gene (goxv247) derived from Ochrobacterum anthropi strain LBAA, or an EPSPS gene with a glyphosate tolerance mutation derived from Zea mays (mepsps or 2mepsps). Main plants include, for example, Medicago sativa, Brassica napus, Gossypium hirsutum L., Agrostis stolonifera, Zea mays L., Brassica rapa, Solanum tuberosum L., Glycine max L., Beta vulgaris, and Triticum aestivum. Some glyphosate-tolerant plants are commercially available. For example, genetically modified plants with CP4 epsps are sold under trademark names including "Roundup Ready®", genetically modified plants with gat4601 or gat4621 are sold under trademark names such as "Optimum GAT™", "Optimum® Gly canola", etc., and genetically modified plants with mepsps or 2mepsps are sold under the trademark name "GlyTol™".More specific glyphosate-tolerant plants include, for example, maize such as "Roundup Ready(Trademark) Maize", "Roundup Ready(Trademark) 2 Maize", "Agrisure(Trademark) GT", "Agrisure(Trademark) GT / CB / LL", "Agrisure(Trademark) GT / RW", "Agrisure(Trademark) 3000GT", "YieldGard(Trademark) VT(Trademark) Rootworm(Trademark) RR2", and "YieldGard(Trademark) VT Triple"; soybean such as "Roundup Ready(Trademark) Soybean" and "Optimum GAT(Trademark)"; cotton such as "Roundup Ready(Trademark) Cotton", "Roundup Ready(Trademark) Flex Cotton", and "GlyTol(Trademark)"; canola such as "Roundup Ready(Trademark) Canola" and "Optimum(Registered Trademark) Gly canola"; alfalfa such as "Roundup Ready(Trademark) Alfalfa"; rice such as "Roundup Ready(Trademark) Rice"; sugar beet such as "Roundup Ready(Trademark) sugarbeet" and "InVigor(Trademark) sugarbeet"; and wheat (Triticum aestivum) sold under the trademark name "Roundup Ready(Trademark) wheat". Glyphosate herbicide-tolerant plants: Obtained by introducing one or more of the genes of phosphinothricin N-acetyltransferase (hereinafter abbreviated as PAT) (bar) derived from Streptomyces hygroscopicus, the PAT gene (pat) derived from Streptomyces viridochromogenes, or the synthetic PAT gene (pat syn) derived from Streptomyces viridochromogenes strain Tu494. Main plants include, for example, Argentine canola (Brassica napus), chicory (Cichorium intybus), cotton (Gossypium hirsutum L.), corn (Zea mays L.), Polish canola (Brassica rapa), rice (Oryza sativa L.), soybean (Glycine max L.), and sugar beet (Beta vulgaris). Some glyphosate-tolerant plants are commercially available. For example, genetically modified plants into which bar or pat has been introduced are sold under the trade names of "LibertyLink (trademark)", "InVigor (trademark)", or "WideStrike (trademark)". More specific glyphosate-tolerant plants are, for example, corn under the trade names of "Roundup Ready (trademark) 2", "Liberty Link (trademark)", "Herculex (trademark) I", "Herculex RW", "Herculex XTRA (trademark)", "Agrisure (trademark) GT / CB / LL", "Agrisure (trademark) CB / LL / RW", and "Bt10"; cotton under the trade name of "FiberMax (trademark) Liberty Link (trademark)"; rice under the trade name of "Liberty Link (trademark) Rice"; canola under the trade name of "inVigor (trademark) Canola"; soybean under the trade name of "Liberty Link (trademark) Soybean"; and sugar beet under the trade name of "Liberty Link (trademark) sugarbeet". Oxynil herbicide (e.g., bromoxynil)-tolerant plants: Obtained by introducing the nitrilase gene (bxn) derived from Klebsiella pneumoniae subsp. Ozaenae. Main plants include, for example, Argentine canola (Brassica napus), cotton (Gossypium hirsutum L.), and tobacco (Nicotiana tabacum L.). Some oxynil herbicide-tolerant plants are commercially available. For example, they are sold under trademark names including "Navigator (trademark)" or "BXN (trademark)". More specific oxynil herbicide-tolerant plants include, for example, cotton sold under the trademark name "BXN (trademark) Cotton"; Argentine canola sold under the trademark name "Navigator (trademark) Cotton". ALS herbicide-tolerant plants: Carnation (Dianthus caryophyllus) into which an ALS gene (surB) conferring ALS herbicide tolerance derived from tobacco (Nicotiana tabacum) has been introduced is sold under a trademark name such as "Moondust (trademark)", "Moonshadow (trademark)", "Moonshade (trademark)", "Moonlite (trademark)", "Moonaqua (trademark)", "Moonvista (trademark)", "Moonique (trademark)", "Moonpearl (trademark)", "Moonberry (trademark)" or "Moonvelvet (trademark)". Flax (Linum usitatissumum L.) into which an ALS gene (als) conferring ALS herbicide tolerance derived from Arabidopsis thaliana has been introduced is sold under a trademark name such as "CDC Triffid Flax". Maize (Zea mays L.) having resistance to sulfonylurea and imidazolinone herbicides into which an ALS gene (zm-hra) conferring ALS herbicide tolerance derived from maize has been introduced is sold under a trademark name such as "Optimum GAT (trademark)". Soybean having resistance to imidazolinone herbicides into which an ALS gene (csr1-2) conferring ALS herbicide tolerance derived from Arabidopsis thaliana has been introduced is sold under a trademark name such as "Cultivance". Soybean (Glycine max) into which an ALS gene (gm-hra) conferring ALS herbicide tolerance derived from soybean has been introduced is sold under a trademark name such as "Treus (trademark)", "Plenish (trademark)" and "Optimum GAT (trademark)". There is also cotton into which an ALS gene (S4-HrA) conferring ALS herbicide tolerance derived from tobacco (Nicotiana tabacum cv. Xanthi) has been introduced. HPPD herbicide-tolerant plants: Obtained by introducing the HPPD gene (avhppd-03) derived from Avena sativa. For example, soybeans into which the PAT gene (pat) derived from Streptomyces viridochromogenes is introduced simultaneously with the above gene are sold under the trade name "Herbicide-tolerant Soybean line" as soybeans resistant to mesotrione and glufosinate. 2,4-D-tolerant plants or ACCase herbicide-tolerant plants: Maize resistant to 2,4-D or ACCase herbicides into which the aryloxyalkanoate dioxygenase gene (aad-1) derived from Sphingobium herbicidovorans is introduced is sold, for example, under the trade name "Enlist® Maize". Soybeans and cotton resistant to 2,4-D or ACCase herbicides into which the aryloxyalkanoate dioxygenase gene (aad-12) derived from Delftia acidovorans is introduced are known and are sold, for example, under the trade name "Enlist® Soybean". Dicamba herbicide-tolerant plants: Obtained by introducing the dicamba monooxygenase gene (dmo) derived from Stenotrophomonas maltophilia strain DI-6. Soybeans and cotton into which the above gene is introduced are known. Soybeans (Glycine max L.) into which the glyphosate-tolerant EPSPS gene (CP4 epsps) derived from Agrobacterium tumefaciens strain CP4 is introduced simultaneously with the above gene are sold, for example, under the trade name "Genuity® Roundup Ready® 2 Xtend®". Additional plants with modified resistance to herbicides are widely known, for example, alfalfa, apple, barley, eucalyptus, flax, grape, chickpea, rapeseed, pea, potato, rice, sugar beet, sunflower, tobacco, tomato, field bindweed, and wheat with resistance to glyphosate (see, for example, US5188642, US4940835, US5633435, US5804425, US5627061); legumes, cotton, soybean, pea, potato, sunflower, tomato, tobacco, maize, sorghum, and sugarcane with resistance to dicamba (see, for example, WO2008 / 051633, US7105724, and US5670454); soybean, sugar beet, potato, tomato, and tobacco with resistance to glufosinate (see, for example, US6376754, US5646024, US5561236); cotton, peppers, apple, tomato, sunflower, tobacco, potato, maize, cucumber, wheat, soybean, sorghum, and minor cereals with resistance to 2,4-D (see, for example, US6153401, US6100446, WO2005 / 107437, US5608147, and US5670454); canola, maize, millet, barley, cotton, mustard, lettuce, lentil, melon, oats, durum wheat, turnip, potato, rice, rye, sorghum, soybean, sugar beet, sunflower, tobacco, tomato, and wheat with resistance to ALS-inhibiting herbicides (for example, sulfonylurea herbicides or imidazolinone herbicides) (see, for example, US5013659, WO2006 / 060634, US4761373, US5304732, US6211438, US6211439, and US6222100), in particular, rice with resistance to imidazolinone herbicides, rice having specific mutations in the acetohydroxyacid synthase gene (for example, S653N, S654K, A122T, S653(At)N, S654(At)K, A122(At)T) (see, for example, US2003 / 0217381, WO2005 / 020673); HPPD-inhibiting herbicides (for example, isoxazole herbicides such as isoxaflutole;Barley, sugarcane, rice, corn, tobacco, soybean, cotton, rapeseed, sugar beet, wheat and potato that are resistant to diketonitrile, a degradation product of isoxaflutole, or to triketone herbicides such as sulcotrione and mesotrione, or pyrazole herbicides such as pyrazolate (see, for example, WO2004 / 055191, WO1996 / 38567, WO1997 / 049816 and US6791014); and wheat, soybean, cotton, sugar beet, rapeseed, rice, corn, sorghum, sugarcane and sugar beet that are resistant to PPO-inhibiting herbicides (see, for example, US2002 / 0073443, US2008 / 0052798, Pest Management Science, 61, 2005, 277-285).;
[0135] Examples of plants with herbicide tolerance conferred by conventional varietal improvement techniques or genomic breeding techniques include rice "Clearfield® Rice", wheat "Clearfield® Wheat", sunflower "Clearfield® Sunflower", lentils "Clearfield® lentils", and canola "Clearfield® canola" (products of BASF), which are resistant to imidazolinone ALS-inhibiting herbicides such as imazetapyr and imazamox; soybean "STS soybean", which is resistant to sulfonylurea ALS-inhibiting herbicides such as thifensulfuron-methyl; corn "SR corn" (also known as "Poast Protected® corn"), which is resistant to acetyl-CoA carboxylase inhibitors such as trioxime herbicides and aryloxyphenoxypropionate herbicides; sunflower "ExpressSun®", which is resistant to sulfonylurea herbicides such as tribenuron; rice "Provisia® Rice", which is resistant to acetyl-CoA carboxylase inhibitors such as quizalofop; canola "Triazine Tolerant Canola", which is resistant to photosystem II inhibitors; and sorghum "Igrowth®", which is resistant to imidazolinone herbicides.
[0136] Examples of plants with herbicide tolerance conferred by genome editing technologies include canola with sulfonylurea herbicide tolerance, "SU Canola (registered trademark)", developed using the Rapid Trait Development System (RTDS (registered trademark)). RTDS (registered trademark) corresponds to oligonucleotide-directed mutagenesis in genome editing technologies and is a technique that can introduce mutations without cleaving DNA in plants via Gene Repair Oligonucleotide (GRON), that is, a chimeric oligonucleotide of DNA and RNA. Other examples include maize with reduced herbicide tolerance and phytic acid content by deleting the endogenous gene IPK1 using zinc finger nuclease (see, for example, Nature 459, 437-441, 2009); and rice with conferred herbicide tolerance using CRISPR-Cas9 (see, for example, Rice, 7, 5, 2014).
[0137] Examples of plants with herbicide tolerance conferred by new breeding technologies include, for example, soybeans in which properties of a GM rootstock were conferred on a scion using a variety improvement technique using grafting. Specifically, examples include soybeans in which glyphosate tolerance was conferred on non-transgenic soybean scions using Roundup Ready (registered trademark) soybeans with glyphosate tolerance as the rootstock (see Weed Technology 2013, 27, 412).
[0138] Examples of plants with pest resistance are given below.
[0139] Examples of plants imparted with resistance to Lepidoptera pests by genetic recombination technology include, for example, maize (Zea mays L.), soybean (Glycine max L.), cotton (Gossypium hirsutum L.), rice (Oryza sativa L.), poplar (Populus sp.), tomato (Lycopersicon esculentum), eggplant (Solanum melongena), and sugarcane (Saccharum sp.) into which a gene encoding a delta-endotoxin, an insecticidal protein derived from the soil bacterium Bacillus thuringiensis (hereinafter abbreviated as Bt bacterium), has been introduced. Examples of delta-endotoxins that impart resistance to Lepidoptera pests include Cry1A, Cry1Ab, modified Cry1Ab (Cry1Ab with some parts deleted), Cry1Ac, Cry1Ab-Ac (a hybrid protein in which Cry1Ab and Cry1Ac are fused), Cry1C, Cry1F, Cry1Fa2 (modified cry1F), moCry1F (modified Cry1F), Cry1A.105 (a hybrid protein in which Cry1Ab, Cry1Ac, and Cry1F are fused), Cry2Ab2, Cry2Ae, Cry9C, Vip3A, and Vip3Aa20. Examples of plants imparted with resistance to Coleoptera pests by genetic recombination technology include, for example, maize and potato into which a gene encoding a delta-endotoxin, an insecticidal protein derived from the Bt bacterium, a soil bacterium, has been introduced. Examples of delta-endotoxins that impart resistance to Coleoptera pests include Cry3A, mCry3A (modified Cry3A), Cry3Bb1, Cry34Ab1, Cry35Ab1, Cry6A, Cry6Aa, and mCry6Aa (modified Cry6Aa). Examples of plants imparted with resistance to Diptera pests by genetic recombination technology include, for example, maize (Zea mays L.) into which a synthetic gene encoding a hybrid protein eCry3.1Ab, which is a fusion of Cry3A and Cry1Ab derived from the soil bacterium Bt, has been introduced, and cotton (Gossypium hirsutum L.) into which a gene encoding a trypsin inhibitor CpTI derived from cowpea (Vigna unguiculata) has been introduced. Furthermore, there are poplars into which a gene encoding a protease inhibitor protein A (API) derived from arrowhead (Sagittaria sagittifolia) has been introduced, which exhibit resistance to a wide range of pests. Insecticidal proteins that confer pest resistance to plants also include hybrid proteins, proteins with partial deletions, and modified proteins of the above insecticidal proteins. Hybrid proteins are produced by combining different domains of multiple insecticidal proteins using genetic recombination technology, and Cry1Ab-Ac and Cry1A.105 are known, for example. As proteins with partial deletions, Cry1Ab with a partial deletion of the amino acid sequence is known. As modified proteins, proteins in which one or more amino acids of the native delta-endotoxin have been substituted are known, such as Cry1Fa2, moCry1F, and mCry3A. In addition, modified proteins also include cases where a proteolytic enzyme recognition sequence that does not naturally exist is inserted into the toxin. For example, Cry3A055 in which a cathepsin G-recognition sequence is inserted into the Cry3A toxin (see WO2003 / 018810) can be mentioned. Cotton (event MON88702) into which a modified BT protein Cry51Aa2 (Cry51Aa2.834_16) has been introduced by genetic recombination technology has been developed by Monsanto and exhibits resistance to species of the genus Lygus such as Lygus lineolaris, Hemiptera such as aphids, and Thysanoptera such as species of the genus Frankliniella. In addition, as insecticidal proteins that confer pest resistance to plants by genetic recombination technology, for example, insecticidal proteins derived from Bacillus cereus or Bacillus popilliae; plant insecticidal proteins Vip1, Vip2, Vip3 (subclasses Vip3Aa to Vip3Aj, Vip3Ba, Vip3B, and Vip3Ca are known, and specifically, for example, Vip3Aa20 and Vip3Aa61 are known) and Vip4; insecticidal proteins derived from nematode-symbiotic (colony-forming in nematodes) bacteria such as Photorhabdus spp. like Photorhabdus luminescens or Xenorhabdus spp. like Xenorhabdus nematophilus; insecticidal protein Tma12 (insecticidal protein Tma12 derived from Tactaria macrodonata) from the fern plant Tectaria macrodonta; insecticidal protein IPD083 (insecticidal protein IPD083 derived from Adiantum spp.) from the fern plant Adiantum spp.; insecticidal protein IPD113 (insecticidal protein IPD113 derived from Pteris cretica cv. albolineata or Pteris umbrosa) from the fern plant Pteris cretica cv. albolineata or Pteris umbrosatoxins produced by animals containing insect-specific neurotoxins such as albolineata or Pteris umbrosa); toxins produced by animals containing insect-specific neurotoxins such as scorpion toxin, spider toxin, bee toxin, etc.; toxins produced by filamentous fungi such as Streptomycetes toxin; plant lectins such as pea lectin, barley lectin, snowdrop lectin; agglutinin; protease inhibitors such as trypsin inhibitor, serine protease inhibitor, patatin, cystatin, papain inhibitor; ribosome-inactivating proteins (RIP) such as ricin, corn-RIP, abrin, luffin, saporin, bryodin; steroid metabolic enzymes such as 3-hydroxy steroid oxidase, ecdysteroid-UDP-glucosyltransferase, cholesterol oxidase; ecdyson inhibitors; HMG-CoA-reductase; ion channel inhibitors such as sodium channel inhibitors, calcium channel inhibitors; juvenile hormone esterase; diuretic hormone receptor; stilbene synthase; bibenzyl synthase; chitinase; and glucanase.
[0140] In addition, plants imparted with pest resistance by introducing one or more insecticidal protein genes are already known, and some plants are commercially available. Examples of cotton with pest resistance include "Bollgard (trademark) cotton", "BXN (trademark) Plus Bollgard (trademark) Cotton", "BXN (trademark) Plus Bollgard (trademark) Cotton", "JK 1", "Roundup Ready (trademark) Bollgard (trademark) Cotton", and "Ingard (trademark)", which express the insecticidal protein Cry1Ac derived from Bacillus thuringiensis (Bt); "Herculex (trademark) I" and "Herculex (trademark) CB", which express the modified insecticidal protein Cry1F (Cry1Fa2) derived from Bt; "VIPCOT (trademark) Cotton", which expresses the insecticidal protein Vip3A derived from Bt; "Bollgard II (trademark) cotton", "Roundup Ready (trademark) Bollgard II (trademark) Cotton", "Roundup Ready (trademark) Flex (trademark) Bollgard II (trademark) Cotton", and "Fivermax (trademark) Liberty Link (trademark) Bollgard II (trademark)", which express the insecticidal proteins Cry1Ac and Cry2Ab derived from Bt; "Bollgard III (registered trademark)" and "Bollgard (registered trademark) III x Roundup Ready (trademark) Flex (trademark)", which express the insecticidal proteins Cry1Ac, Cry2Ab, and Vip3A derived from Bt; "VIPCOT (trademark) Roundup Ready Flex (trademark) Cotton", which expresses the insecticidal proteins Vip3A and Cry1Ab derived from Bt; "VIPCOT (registered trademark) Cotton", which expresses the insecticidal proteins Vip3A and Cry1Ac derived from Bt; "WideStrike (trademark) Cotton", "WideStrike (trademark) Roundup Ready (trademark) Cotton", and "Widestrike (trademark) Roundup Ready Flex (trademark) Cotton", which express the insecticidal proteins Cry1Ac and Cry1F derived from Bt; "TwinLink (trademark) Cotton" and "Glytol (trademark) x Twinlink (trademark)", which express the insecticidal proteins Cry1Ab and Cry2Ae derived from Bt;"Widestrike® 3" and "Widestrike™ x Roundup Ready Flex™ x VIPCOT™ Cotton", which express the insecticidal proteins Cry1Ac, Cry1F and Vip3A derived from Bt bacteria; "Glytol™ x Twinlink™ x VIPCOT™ Cotton", which express the insecticidal proteins Cry1Ab, Cry2Ae and Vip3A derived from Bt bacteria, are commercially available.; Examples of corn with pest resistance include "YieldGard® Rootworm RW", "YieldGard® RW + RR", "YieldGard® VT® Rootworm® RR2", and "MaxGard®", which express the insecticidal protein Cry3Bb1 derived from Bt bacteria; "YieldGard® VT Triple" and "YieldGard® Plus with RR", which express the insecticidal proteins Cry3Bb1 and Cry1Ab derived from Bt bacteria; "Bt Xtra® Maize", which expresses the insecticidal protein Cry1Ac derived from Bt bacteria; "YieldGard Plus®", which expresses the insecticidal proteins Cry1Ab and Cry3Bb1 derived from Bt bacteria; "Bt10", "Liberty Link® Yieldgard® Maize", "Agrisure® GT / CB / LL", and "YieldGard® CB + RR", which express the insecticidal protein Cry1Ab derived from Bt bacteria; and the insecticidal protein Cry1A. derived from Bt bacteria."YieldGard® VT Pro®" and "Genuity® VT Double Pro®" that express 105 and Cry2Ab2; "Agrisure® RW" and "Agrisure® GT / RW" that express the insecticidal protein mCry3A derived from Bt bacteria; "Starlink® Maize" that expresses the insecticidal protein Cry9C derived from Bt bacteria; "YieldGard®", "MaizeGard®", "NaturGard KnockOut®", "Maximizer®", "Roundup Ready® YieldGard® maize", "Agrisure® CB / LL" and "Mavera® YieldGard® Maize" that express the insecticidal protein Cry1Ab derived from Bt bacteria; "Agrisure® 3122" that expresses the insecticidal proteins Cry1Ab, Cry1F, modified Cry3A, Cyr34Ab1 and Cyr35Ab1 derived from Bt bacteria; "Agrisure® Viptera" that expresses the insecticidal protein Vip3Aa20 derived from Bt bacteria; "Agrisure® Viptera® 2100" and "Agrisure® Viptera® 3110" that express the insecticidal proteins Vip3Aa20 and Cry1Ab derived from Bt bacteria; "Agrisure® Viptera® 3100", "Agrisure® Viptera® 3111)" and "Agrisure® Viptera® 4" that express the insecticidal proteins Vip3Aa20, Cry1Ab and modified Cry3A derived from Bt bacteria; "Agrisure® Viptera® 3220" that expresses the insecticidal proteins Vip3Aa20, Cry1Ab and modified Cry1F derived from Bt bacteria; "Agrisure® Duracade®" that expresses the insecticidal protein eCry3.1Ab (a chimeric protein of Cry3A-Cry1Ab) derived from Bt bacteria; the insecticidal protein eCry3.1Ab (Cry3A-Cry1Ab chimeric protein), modified Cry3A, Cry1Ab, and modified Cry1F-expressing "Agrisure® Duracade™ 5122"; Bt bacterium-derived insecticidal protein eCry3.1Ab (Cry3A-Cry1Ab chimeric protein), modified Cry3A, modified Cry1Ab, and Vip3A variant-expressing "Agrisure® Duracade™ 5222"; Bt bacterium-derived insecticidal proteins Cyr34Ab1 and Cyr35Ab1-expressing "Herculex™ RW"; Bt bacterium-derived insecticidal proteins Cyr34Ab1, Cyr35Ab1, and Cry1F-expressing "Herculex XTRA™"; Bt bacterium-derived insecticidal proteins Cry1A.105, Cry2Ab2, and Cry3Bb1-expressing "Genuity® VT Triple Pro™"; Bt bacterium-derived insecticidal proteins Cry1F, Cry2Ab, Cyr34Ab1, Cyr35Ab1, Cry3Bb1, and Cry1A.105-expressing "Genuity® SmartStax™"; Bt bacterium-derived insecticidal proteins modified Cry1F, Cry2Ab, and Cry1A.105-expressing "Power Core™"; Bt bacterium-derived insecticidal proteins modified Cry1F, Cyr34Ab1, and Cyr35Ab1-expressing "Herculex XTRA™ RR"; Bt bacterium-derived insecticidal proteins modified Cry1F, Cyr34Ab1, Cyr35Ab1, Cry1Ab, and modified Cry3A-expressing "Optimum® Intrasect Xtreme"; Bt bacterium-derived insecticidal proteins modified Cry1F, Cyr34Ab1, Cyr35Ab1, and Cry1Ab-expressing "Optimum® Intrasect XTRA"; Bt bacterium-derived insecticidal proteins modified Cry1F and modified Cyr3A-expressing "Optimum® TRIsect", and these are commercially available. Examples of other plants imparted with pest resistance include the potato varieties "Atlantic NewLeaf™ potato", "NewLeaf™ Russet Burbank potato", "Lugovskoi plus", "Elizaveta plus", "Hi-Lite NewLeaf™ Y potato, Superior NewLeaf™ potato" and "Shepody NewLeaf™ Y potato" expressing the insecticidal protein Cry3A derived from Bacillus thuringiensis (Bt); the rice varieties "hanyou 63" and "Huahui-1" expressing the insecticidal proteins Cry1Ab and Cry1Ac derived from Bt; the soybean variety "Intacta™ Roundup Ready™ 2 Pro" expressing the insecticidal protein Cry1Ac derived from Bt; and the eggplant varieties "BARI Bt Begun-1, -2, -3 and -4" expressing the insecticidal protein Cry1Ac derived from Bt, which are commercially available. Also, corn varieties with resistance to corn rootworms, such as "YieldGard corn rootworm", "YieldGard VT", "Herculex RW", "Herculex Rootworm", and "Agrisure CRW"; corn varieties with resistance to corn borers, such as "YieldGard corn borer", "YieldGard plus", "YieldGard VT Pro", "Agrisure CB / LL", "Agrisure 3000GT", "Hercules I", "Hercules II", "KnockOut", "NatureGard", and "StarLink"; corn varieties with resistance to western bean cutworm, corn borer, black cutworm, and fall armyworm, such as "Herculex I", "Herculex Xtra", "NewLeaf", "NewLeaf Y", and "NewLeaf Plus"; corn varieties with resistance to corn borer and corn rootworm, such as "YieldGard Plus"; cotton varieties with resistance to pink bollworm, such as "Bollgard I" and "Bollgard II"; cotton varieties with resistance to pink bollworm, cotton bollworm, fall armyworm, beet armyworm, cabbage looper, soybean looper, and pink bollworm, such as "Bollgard II", "WideStrike (trademark)", and "VipCot"; potato varieties with resistance to Colorado potato beetle, such as "NewLeaf", "NewLeaf Y", and "NewLeaf Plus"; eggplant varieties with resistance to eggplant fruit and shoot borer and cotton bollworm, such as "Bt brinjal", "Dumaguete Long Purple", and "Mara" (see, for example, US5128130) are known. Additional plants with pest resistance are generally known, for example, stem borer-resistant rice (see, for example, Molecular Breeding, Vol. 18 (2006), No. 1), Lepidoptera-resistant lettuce (see, for example, US5349124), and rice with resistance to Lepidoptera (such as Chilo suppressalis, Plutella xylostella, Sesamia inferens, Mythimna separata, rice caseworm, and rice armyworm) (see, for example, WO2001 / 021821). Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the above publications.
[0141] As plants imparted with pest resistance by RNA interference technology, corn having resistance to coleopteran pests (corn rootworms) is commercially available under the trade names "SmartStax® Pro" or "Vorceed Enlist®".
[0142] As plants imparted with pest resistance by conventional breeding techniques or genomic breeding techniques, for example, soybeans having resistance to soybean aphids (Aphis glycines) with the "Rag1 (Resistance to Aphis glycines 1)" gene or "Rag2 (Resistance to Aphis glycines 2)" gene, which are aphid resistance genes (see J. Econ. Entomol., 2015, 108, 326); soybeans having resistance to soybean cyst nematode (Heterodera glycines) (see Phytopathology, 2016, 106, 1444); cotton having resistance to root-knot nematode (Meloidogyne incognita) (see J. Nematol., 2009, 41, 140); rice "Kanto BPH1" having resistance to brown planthopper; and soybean "Fukuminori" having resistance to Spodoptera litura can be mentioned.
[0143] These plants imparting pest resistance are imparted with resistance to any harmful insects (particularly, Lepidoptera insects, Coleoptera insects, Diptera insects, beetle insects), harmful spiders, and harmful nematodes. The plants imparting pest resistance are preferably selected from wheat (e.g., common wheat, barley, rye, oat), corn, canola, sorghum, soybean, rice, rapeseed, sugar beet, sugarcane, grape, lentil, sunflower, alfalfa, pome fruits, stone fruits, peanuts, coffee, tea, strawberries, turfgrass, vegetables (e.g., tomato, potato, cucurbitaceae plants, and lettuce), more preferably selected from soybean, corn, tomatoes, rice, and wheat (e.g., common wheat, barley, rye, and oat), and most preferably selected from soybean, rice, corn, and wheat (e.g., common wheat, barley, rye, and oat).
[0144] Examples of plants imparting disease resistance are given below.
[0145] Plants imparted with disease resistance by genetic recombination technology are, for example, plants that express so-called "pathogenesis-related proteins" (PRPs, see, for example, EP0392225) or so-called "antifungal proteins" (AFPs, see, for example, US6864068). Various antifungal proteins having activity against phytopathogenic fungi have been isolated from specific plant species and are common knowledge. Examples of such anti-pathogenic substances and plants capable of synthesizing such anti-pathogenic substances are known, for example, from EP0392225, WO1993 / 05153, WO1995 / 33818, and EP0353191. Plants resistant to fungicidal pathogens, viral pathogens, and bacterial pathogens are produced by introducing disease resistance genes. A number of resistance genes have been identified, isolated, and used to improve disease resistance. Examples of such resistance genes include, for example, the N gene introduced into a tobacco line sensitive to tobacco mosaic virus (TMV) to produce a TMV-resistant tobacco plant (see, for example, US 5571706), the Prf gene introduced into a plant to obtain enhanced pathogen resistance (see, for example, WO1998 / 02545), and the Rps2 gene derived from Arabidopsis thaliana used to create resistance to bacterial pathogens such as Pseudomonas syringae (see, for example, WO1995 / 028423). Plants showing a systemic acquired resistance response were obtained by introducing a nucleic acid molecule encoding the TIR domain of the N gene (see, for example, US 6630618).As further examples of well-known resistance genes, there are the Xa21 gene introduced into numerous rice varieties (see, for example, US5952485, US5977434, WO1999 / 009151, WO1996 / 022375), the Rcg1 gene for resistance to Colletotrichum (see, for example, US2006 / 225152), the prp1 gene (see, for example, US5859332, WO2008 / 017706), the ppv-cp gene for introducing resistance to plum pox virus (see, for example, US PP15,154Ps), the P1 gene (see, for example, US5968828), genes such as Blb1, Blb2, Blb3, RB2, and Rpi-vnt1 for introducing resistance to Phytophthora infestans in potatoes (see, for example, US7148397), the LRPKml gene (see, for example, WO1999 / 064600), the P1 gene for resistance to potato virus Y (see, for example, US5968828), the HA5-1 gene (see, for example, US5877403 and US6046384), the PIP gene for introducing broad resistance to viruses such as potato virus X (PVX), potato virus Y (PVY), and potato leafroll virus (PLRV) (see, for example, EP0707069), and genes such as the NI16 gene, ScaM4 gene, and ScaM5 gene of Arabidopsis for obtaining fungal resistance (see, for example, US6706952 and EP1018553). In addition, beans resistant to bean golden mosaic virus (hereinafter referred to as BGMV) are plants to which resistance has been imparted by RNA interference technology. By introducing a double-stranded RNA gene (sense and antisense ac1 gene) of the replication protein, the synthesis of the BGMV replication protein is inhibited, thereby showing resistance to BGMV. Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the above publications. Examples of anti-pathogenic substances that can be expressed by such plants include, for example, ion channel blockers (sodium channel blockers, calcium channel blockers, etc.); viral KP1, KP4, and KP6 toxins; stilbene synthase; bibenzyl synthase; chitinase; glucanase; so-called "pathogenesis-related proteins" (PRPs; see, for example, EP0392225); anti-pathogenic substances produced by microorganisms (for example, peptide antibiotics, heterocyclic antibiotics (see, for example, WO1995 / 033818), and protein factors or polypeptide factors involved in plant pathogen defense (so-called "plant disease resistance genes" described in WO2003 / 000906)). Anti-pathogenic substances produced by plants can protect plants from various pathogenic microorganisms such as fungi, viruses, and bacteria. Useful plants that have been attracting increasing interest in relation to the present invention are wheat (for example, common wheat, barley, rye, and emmer), soybean, corn, rice, rapeseed, pome fruits, stone fruits, peanuts, coffee, tea, strawberry, turfgrass; vine plants and vegetables (for example, tomato, potato), cucurbitaceae plants, papaya, melon, lentils, and lettuce, more preferably selected from soybean, tomato, rice, and wheat (for example, common wheat, barley, rye, and emmer), and most preferably selected from soybean, rice, and wheat (for example, common wheat, barley, rye, and emmer). Examples of plants having resistance to fungal pathogens include, for example, soybeans having resistance to soybean rust pathogens (Phakopsora pachyrhizi and Phakopsora meibomiae) (see, for example, WO2008 / 017706); solanaceous plants such as cotton, tomatoes, and potatoes having resistance to the potato late blight pathogen (phytophthora infestans) (see, for example, US5859332, US7148397, EP1334979); corn having resistance to Colletotrichum such as Colletotrichum graminicola (see, for example, US2006 / 225152); apples having resistance to the apple scab pathogen (venturia inaequalis) (see, for example, WO1999 / 064600); plants having resistance to Fusarium spp. (for example, fusarium graminearum, fusarium sporotrichioides, fusarium lateritium, fusarium pseudograminearum, fusarium sambucinum, fusarium culmorum, fusarium poae, fusarium acuminatum, fusarium equiseti) (for example, rice, wheat, barley, rye, corn, oats, potatoes, melons, soybeans, and sorghum) (see, for example, US6646184, EP1477557); plants such as corn, soybeans, wheat (especially wheat, barley, rye, and oats), rice, tobacco, sorghum, sugarcane, and potatoes having broad-spectrum fungicide resistance (see, for example, US5859332, US5689046, US6706952, EP1018553, and US6020129). Examples of plants having resistance to bacterial pathogens include, for example, rice having resistance to Xylella fastidiosa (see, for example, US6232528); plants such as rice, cotton, soybean, potato, sorghum, corn, wheat, barley, sugarcane, tomato, and pepper having resistance to bacterial stem rot pathogens (see, for example, WO2006 / 42145, US5952485, US5977434, WO1999 / 09151, WO1996 / 22375); and tomato having resistance to Pseudomonas syringae (see, for example, Can. J. Plant Path., 1983, 5:251-255). Examples of plants resistant to viral pathogens include, for example, stone fruits (e.g., plum, almond, apricot, cherry, peach, nectarine) resistant to plum pox virus (see, e.g., US PP15154Ps, EP0626449); potatoes resistant to potato virus Y (see, e.g., US5968828); plants such as potatoes, tomatoes, cucumbers, and legumes resistant to tomato spotted wilt virus (see, e.g., EP0626449, US5973135); maize resistant to maize streak virus (see, e.g., US6040496); papaya resistant to papaya ring spot virus (see, e.g., S5877403, US6046384); cucurbitaceae plants (e.g., cucumber, melon, watermelon, and pumpkin) and solanaceae plants (e.g., potato, tobacco, tomato, eggplant, pepper, paprika, pepper, and chili pepper) resistant to cucumber mosaic virus (see, e.g., US6849780); cucurbitaceae plants (e.g., cucumber, melon, watermelon, and pumpkin) resistant to watermelon mosaic virus 2 and zucchini yellow mosaic virus (see, e.g., US6015942); potatoes resistant to potato leafroll virus (see, e.g., US5576202); potatoes with broad resistance to viruses such as potato virus X, potato virus Y, and potato leafroll virus (see, e.g., EP0707069);Examples include common beans resistant to Bean golden mosaic virus (see, for example, Mol Plant Microbe Interact. 2007 Jun;20(6):717-26.).; There are plants that are resistant to antibiotics (e.g., kanamycin, neomycin, and ampicillin). The naturally occurring bacterial nptII gene expresses an enzyme that blocks the action of the antibiotics kanamycin and neomycin. The ampR (also known as blaTEM1), an ampicillin resistance gene, is derived from the bacterium Salmonella paratyphi and is used as a marker gene in the transformation of microorganisms and plants. ampR is involved in the synthesis of beta-lactamase, an enzyme that neutralizes penicillin group antibiotics including ampicillin. Plants having resistance to antibiotics include, for example, potato, tomato, flax, canola, rapeseed, Brassica seeds, and corn (e.g., see Plant Cell Reports, 20, 2001, 610 - 615; Trends in Plant Science, 11, 2006, 317 - 319; Plant Molecular Biology, 37, 1998, 287 - 296; Mol Gen Genet., 257, 1998, 606 - 13; Plant Cell Reports, 6, 1987, 333 - 336; Federal Register (USA), Vol. 60, No. 113, 1995, p. 31139; Federal Register (USA), Vol. 67, No. 226, 2002, 70392; Federal Register (USA), Vol. 63, No. 88, 1998, 25194; Federal Register (USA), Vol. 60, No. 141, 1995, 37870; Canadian Food Inspection Agency, FD / OFB - 095 - 264 - A, October 1999, FD / OFB - 099 - 127 - A, October 1999). Preferably, the above plants are selected from soybeans, tomatoes, and cereals (e.g., wheat, barley, rye, and oats), and most preferably from soybeans and cereals (e.g., wheat, barley, rye, and oats). Examples of plants imparted with resistance to plant viral diseases that are available include, for example, papaya “Rainbow,” “SunUp,” and “Huanong No. 1” imparted with resistance to Papaya ringspot virus; potato “Innate (registered trademark) Hibernate,” “Innate (registered trademark) Glaciate,” and “Innate (registered trademark) Acclimate” showing resistance to phytophthora infestans; and potato “Newleaf (trademark)” showing resistance to potato virus Y and / or potato leafroll virus (PLRV).
[0146] As plants with disease resistance conferred by conventional breeding techniques or genomic breeding techniques, rice with resistance to blast; rice with resistance to sheath blight; wheat with resistance to leaf rust; wheat with resistance to stripe rust; wheat with resistance to stem rust; wheat with resistance to powdery mildew; wheat with resistance to leaf blotch; wheat with resistance to glume blotch; wheat with resistance to tan spot; barley with resistance to powdery mildew; barley with resistance to dwarf leaf rust; barley with resistance to net blotch; barley with resistance to scald; barley with resistance to Ramularia disease; corn with resistance to Anthracnose; corn with resistance to gray leaf spot; corn with resistance to Goss's wilt; corn with resistance to Fusarium stalk rot; soybean with resistance to Asian soybean rust; soybean with resistance to phytophthora stem and root rot; soybean with resistance to sudden death syndrome; pepper with resistance to Phytophthora rot; lettuce with resistance to powdery mildew; tomato with resistance to bacterial wilt; tomato with resistance to Gemini virus;Lettuce imparted with resistance to downy mildew; Brassicaceae plants such as rapeseed, cabbage, Brussels sprouts, cauliflower, kale, broccoli, etc. imparted with resistance to clubroot; Brassicaceae plants such as rapeseed, cabbage, Brussels sprouts, cauliflower, kale, broccoli, etc. imparted with resistance to black leg; Melons imparted with resistance to Fusarium wilt of melon caused by Fusarium oxysporum f.sp. melonis (see, for example, WO2009 / 000736).;
[0147] Examples of plants with disease resistance conferred by genome editing technology include: bread wheat that shows resistance to powdery mildew by deleting the mildew resistance locus O (MLO) gene using TALEN and CRISPR-Cas9 (see, for example, Nat. Biotech., 32, 947-951, 2014); slmlo1 tomato that shows resistance to powdery mildew by deleting the SlMLO1 gene, one of the MLO genes, using CRISPR-Cas9 (see, for example, Scientific Reports 7, Article number: 482, 2017); rice that shows resistance to Xanthomonas oryzae pv. Oryzae, which causes bacterial leaf blight, by editing the OsSWEET14 gene in rice using TALEN (see Nat. Biotechnol. 30, 390-392, 2012); rice that shows resistance to Magnaporthe oryzae, which causes blast, by modifying the OsERF922 gene in rice using CRISPR-Cas9 (see PLoS ONE 11: e0154027. doi: 10.1371 / journal.pone.0154027, 2016); cucumber that shows resistance to cucumber vein yellowing virus (CVYV), zucchini yellow mosaic virus (ZYMV), and papaya ringspot virus-type W (PRSV-W) by disrupting the recessive eIF4E (eukaryotic translation initiation factor 4E) gene using CRISPR-Cas9 (see Mol. Plant Pathol.(see Mol Plant Pathol 17(1)127 - 139, 2016); soybeans that are resistant to phytophthora stem and root rot caused by Phytophthora sojae by disrupting the RXLR effector gene (Avr4 / 6) using CRISPR - Cas9 (see Mol Plant Pathol 17(1)1140 - 1153, 2016).
[0148] As plants with disease resistance conferred by new breeding techniques, apples resistant to apple scab caused by Venturia inaequalis by introducing the Rvi6 (formerly called HcrVf2) gene using cisgenesis (see, for example, Plant Biotech.J., 12, 2 - 9, 2014); as an example of imparting the properties of a GM rootstock, which is a variety improvement technique using grafting, to a scion, sweet cherries in which the property of resistance to Prunus necrotic ringspot virus infection was transferred from a transgenic rootstock to a non - transgenic scion (see Plant Biotech. J., 12, 1319 - 1328, 2014).
[0149] Examples of plants with modified product quality are given below. Modifying the quality of the product means increasing or decreasing the synthesis of the modified component or the amount of component synthesis compared to the corresponding wild - type plant. Examples of plants with modified product quality include, for example, plants with increased or decreased contents of vitamins, amino acids, proteins, starch, various oils, and plants with decreased nicotine content.
[0150] Plants whose product quality has been modified by genetic recombination technology include, for example, alfalfa in which the lignin content has been reduced by RNA interference by introducing a gene that produces double-stranded RNA of the S-adenosyl-L-methionine: trans-caffeoyl CoA 3-O-methyltransferase (ccomt) gene derived from alfalfa involved in lignin production; canola "Laurical (trademark) Canola" in which the content of triacylglycerol containing lauric acid has increased by introducing the 12:0 ACP thioesterase gene derived from Umbellularia californica involved in fatty acid synthesi...
Claims
1. Formula (I) 【Chemistry 1】 [During the ceremony, L is a single bond or -(CR 4a R 4b ) n - represents R 4a and R 4b are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, a C1-C6 alkoxy group optionally substituted with one or more halogen atoms, a cyano group, a hydroxy group, a halogen atom, or a hydrogen atom, n represents 1, 2, 3, 4, 5, or 6; R 1 represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from the group consisting of a cyclopropyl group and a halogen atom, a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, a C1-C6 alkoxy group optionally substituted with one or more halogen atoms, a cyano group, a halogen atom, a hydroxy group, or a hydrogen atom; Q represents a group represented by formula Q1, a group represented by formula Q2, a group represented by formula Q3, a group represented by formula Q4, a group represented by formula Q5, a group represented by formula Q6, a group represented by formula Q7, a group represented by formula Q8, a group represented by formula Q9, a group represented by formula Q10, a group represented by formula Q11, a group represented by formula Q12, a group represented by formula Q13, or a group represented by formula Q14 (● represents a bonding site); 【Chemistry 2】 【Chemistry 3】 【Chemistry 4】 【Chemistry 5】 Z represents an oxygen atom or a sulfur atom; A 1 is N.R. 1a , a sulfur atom, or an oxygen atom; R 1a represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, C(O)R 5 , C(O)OR 5 , C(O)NR 6a R 7a or a hydrogen atom, R 1aa , R 1ab , R 2aa , and R 2ab are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, OR 18 , S(O) m R 29 , N.R. 8 C(O)R 5 , N.R. 8 C(O)OR 5 , N.R. 8 C(O)NR 5 R 12a , C(O)NR 6a R 7a , C(=NOR 9a ) R 5 , C(=NOR 9a ) (NR 6a R 7a ), N=S(O) p R 24a R 15 , a halogen atom, a mercapto group, a cyano group, or a hydrogen atom; R 18 represents a phenyl group which may be substituted by one or more substituents selected from group B, a 5- or 6-membered heterocyclic group which may be substituted by one or more substituents selected from group B, a C1-C6 alkyl group which may be substituted by one or more halogen atoms, or a hydrogen atom; R 29 represents a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a phenyl group optionally substituted with one or more substituents selected from group B, or a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, R 24a , R 24b , R 24c , R 24d , and R 24 are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, or a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, R 2a , R 2b , R 2c , R 2d , R 2f , R 2g , R 2h , R 2i , R 2j , R 2k , R 2m , R 2n , and R 2o are the same or different and each represents a phenyl group which may be substituted with one or more substituents selected from group A, a 5- or 6-membered aromatic heterocyclic group which may be substituted with one or more substituents selected from group A, C(O)NR 6b R 7b , C(=NOR 9b ) R 5 , C(=NOR 9b ) (NR 6b R 7b ), N.R. 19 C(O)R 20 , N.R. 19 C(O)OR 20 , N.R. 19 C(O)NR 20 R 21 , S(O) 2 N.R. 16 R 17 , OR 18 , S(O) m R 29 , a group represented by formula E1, a group represented by formula E2, or a group represented by formula E3, 【Chemistry 6】 # 2 represents the binding site, R 2e represents a phenyl group which may be substituted with one or more substituents selected from group A, a 5- or 6-membered aromatic heterocyclic group which may be substituted with one or more substituents selected from group A, C(O)NR 6b R 7b , C(=NOR 9b ) R 5 , C(=NOR 9b ) (NR 6b R 7b ), a group represented by formula E1, a group represented by formula E2, or a group represented by formula E3, m represents 0, 1, or 2; p represents 0 or 1; R 19 , R 20 , and R 21 are the same or different and represent a phenyl group which may be substituted by one or more substituents selected from group B, a 5- or 6-membered heterocyclic group which may be substituted by one or more substituents selected from group B, a C1-C6 alkyl group which may be substituted by one or more halogen atoms, a C3-C6 cycloalkyl group which may be substituted by one or more substituents selected from group E, or a hydrogen atom; R 2a , R 2b , R 2c , R 2d , R 2f , R 2g , R 2h , R 2i , R 2j , R 2k , R 2m , R 2n , or R 2o is NR 19 C(O)R 20 If R 19 and R 20 is R 19 A nitrogen atom to which R is bonded, 20 may form, together with the carbon atom to which it is bonded, a 5- or 6-membered non-aromatic heterocycle or a 5- or 6-membered aromatic heterocycle {the 5- or 6-membered non-aromatic heterocycle and the 5- or 6-membered aromatic heterocycle may be substituted with a C1-C3 chain hydrocarbon group which may be substituted with one or more halogen atoms}, R 2a , R 2b , R 2c , R 2d , R 2f , R 2g , R 2h , R 2i , R 2j , R 2k , R 2m , R 2n , or R 2o is NR 19 C(O)OR 20 If R 19 and R 20 is R 19 a nitrogen atom to which is bonded, C(O), and R 20 may form a 5- or 6-membered non-aromatic heterocycle or a 5- or 6-membered aromatic heterocycle together with the oxygen atom to which it is bonded {the 5- or 6-membered non-aromatic heterocycle and the 5- or 6-membered aromatic heterocycle may be substituted with a C1-C3 chain hydrocarbon group which may be substituted with one or more halogen atoms}, R 2a , R 2b , R 2c , R 2d , R 2f , R 2g , R 2h , R 2i , R 2j , R 2k , R 2m , R 2n , or R 2o is NR 19 C(O)NR 20 R 21 If R 19 and R 20 is R 19 a nitrogen atom to which is bonded, C(O), and R 20 may form a 5- or 6-membered non-aromatic heterocycle or a 5- or 6-membered aromatic heterocycle together with the nitrogen atom to which it is bonded {the 5- or 6-membered non-aromatic heterocycle and the 5- or 6-membered aromatic heterocycle may be substituted with a C1-C3 chain hydrocarbon group which may be substituted with one or more halogen atoms}, R 16 represents a C1-C6 chain hydrocarbon group which may be substituted with one or more substituents selected from group C, a C3-C6 cycloalkyl group which may be substituted with one or more substituents selected from group E, or a hydrogen atom; R 17 represents a C1-C6 chain hydrocarbon group which may be substituted with one or more substituents selected from group C, a phenyl group which may be substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group which may be substituted with one or more substituents selected from group B, a C3-C6 cycloalkyl group which may be substituted with one or more substituents selected from group E, or a hydrogen atom, E 1 is CR 22a or a nitrogen atom, E 2 is CR 22 R 27 , N.R. 23 , an oxygen atom, or a sulfur atom; E 3 is CR 22b or a nitrogen atom, E 4 is CR 22c or a nitrogen atom, E 5 is CR 22d or a nitrogen atom, E 6 is CR 22e or a nitrogen atom (provided that E 3 and E 4 is simultaneously a nitrogen atom, E 3 , E 5 , and E 6 are simultaneously a nitrogen atom, and E 4 , E 5 , and E 6 is also a nitrogen atom) E 7 is CR 22f or a nitrogen atom, R 22 , R 22a , R 22b , R 22c , R 22d , R 22e , and R 22f are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a C1-C6 alkoxy group optionally substituted with one or more halogen atoms, C(O)NR 6c R 7c , N.R. 8 C(O)R 5 a C3-C6 cycloalkyl group optionally substituted by one or more substituents selected from group E, a cyano group, a halogen atom, or a hydrogen atom; R 27 represents a C1-C6 chain hydrocarbon group which may be substituted with one or more substituents selected from the group consisting of a halogen atom and a cyano group, a phenyl group which may be substituted with one or more substituents selected from group B, or a hydrogen atom; R 5 , R 7a , R 7b , R 7c , R 7d , R 7e , R 7f , R 7g , R 7 , R 9a , R 9b , R 9c , R 9d , and R 9 are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, or a hydrogen atom; R 6a , R 6b , R 6c , R 6d , R 6e , R 6f , R 6g , R 6 , R 8 , R 12a , R 12 , R 23 , and R 25 are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, or a hydrogen atom; R 15 represents a C1-C4 chain hydrocarbon group which may be substituted with one or more substituents selected from group C, a phenyl group which may be substituted with one or more substituents selected from group B, or a 5- or 6-membered aromatic heterocyclic group which may be substituted with one or more substituents selected from group B, X is NR 10 C(Z 1 ) R 11 , N.R. 10 C(O)OR 11 , N.R. 10 C(Z 1 ) N.R. 11 R 12 , N.R. 10 C (=NOR 9c ) R 11 , N.R. 10 C (=NOR 9c ) (NR 11 R 12 ), N=C(OR 9c ) R 11 , N=C(SR 15 ) R 11 , N=C(NR 6d R 7d ) R 11 , N.R. 10 X 1 Or N=S(O) p R 11 R 24b represents Z 1 represents an oxygen atom or a sulfur atom, R 10 represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group F, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, a C1-C6 alkylsulfonyl group optionally substituted with one or more halogen atoms, OR 14 , C(O)R 13 , C(O)OR 13 , C(=NR 7e ) R 13 , C(O)NR 6e R 7e or a hydrogen atom, R 11 represents a phenyl group which may be substituted with one or more substituents selected from group A, or a 5- or 6-membered aromatic heterocyclic group which may be substituted with one or more substituents selected from group A, R 14 represents a C1-C6 chain hydrocarbon group which may be substituted with one or more halogen atoms, a C3-C6 cycloalkyl group which may be substituted with one or more halogen atoms, a phenylmethyl group (the phenyl moiety in the phenylmethyl group may be substituted with one or more halogen atoms), a phenyl group which may be substituted with one or more halogen atoms, or a hydrogen atom, R 13 represents a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a phenyl group {the phenyl group is optionally substituted with one or more substituents selected from the group consisting of a C1-C6 alkoxy group optionally substituted with one or more halogen atoms, a C1-C6 alkyl group optionally substituted with one or more halogen atoms, a halogen atom, and a cyano group}, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, or a hydrogen atom, R 1ac , R 1ad , R 1ae , R 1af , R 2ac , R 2ad , R 2ae , R 2af , R 3ac , R 4ac , R 5af , R 6af , R 7ae , and R 8ae are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, NR 8 C(O)R 5 , N.R. 8 C(O)OR 5 , N.R. 8 C(O)NR 5 R 7f , C(O)NR 6f R 7f , C(=NOR 9d ) R 5 , C(=NOR 9d ) (NR 6f R 7f ), OR 18 , S(O) m R 29 Or N=S(O) p R 24c R 15 , a cyano group, a halogen atom, or a hydrogen atom; A 2 , A 3 , A 4 and A 5 The combination of A 2 is CR 2ac And A 3 is CR 2ad And A 4 is a nitrogen atom, A 5 is a nitrogen atom or CR 2af A combination in which: A 2 is CR 2ac And A 3 is CR 2ad And A 4 is CR 2ae And A 5 is a nitrogen atom; A 2 is CR 2ac And A 3 is a nitrogen atom, A 4 is CR 2ae And A 5 is a nitrogen atom or CR 2af A combination in which: A 2 is CR 2ac And A 3 is a nitrogen atom, A 4 is a nitrogen atom, A 5 is CR 2af A combination in which: A 2 is a nitrogen atom, A 3 is CR 2ad And A 4 is a nitrogen atom, A 5 is CR 2af A combination in which: A 2 is a nitrogen atom, A 3 is CR 2ad And A 4 is CR 2ae And A 5 is a nitrogen atom or CR 2af or A 2 is a nitrogen atom, A 3 is a nitrogen atom, A 4 is CR 2ae And A 5 is CR 2af represents a combination where A 6 and A 9 are the same or different and each represents an oxygen atom, a sulfur atom, or NR 26 represents A 7 and A 8 are the same or different, CR 28 or a nitrogen atom, R 1b , R 1c , R 1d , R 1e , R 1f , R 1g , R 1h , R 1i , R 1j , R 1k , R 1m , R 1n , R 1o , and R 1p are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, NR 8 C(O)R 5 , N.R. 8 C(O)OR 5 , N.R. 8 C(O)NR 5 R 7g , C(O)NR 6g R 7g , C(=NOR 9 ) R 5 , C(=NOR 9 ) (NR 6g R 7g ), OR 18 , S(O) m R 29 Or N=S(O) p R 24d R 15 , a cyano group, a halogen atom, or a hydrogen atom; R 3af , R 4ae , R 5ac , R 6ae , and R 26 are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, or a hydrogen atom; R 28 represents a C1-C6 chain hydrocarbon group optionally substituted with one or more substituents selected from group C, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, NR 8 C(O)R 5 , N.R. 8 C(O)OR 5 , N.R. 8 C(O)NR 5 R 7 , C(O)NR 6 R 7 , C(=NOR 9 ) R 5 , C(=NOR 9 ) (NR 6 R 7 ), OR 18 , S(O) m R 29 Or N=S(O) p R 24 R 15 , a cyano group, a halogen atom, or a hydrogen atom; When Q is a group represented by formula Q1, a group represented by formula Q2, a group represented by formula Q3, a group represented by formula Q4, a group represented by formula Q6, a group represented by formula Q7, a group represented by formula Q8, a group represented by formula Q9, a group represented by formula Q10, a group represented by formula Q11, a group represented by formula Q12, a group represented by formula Q13, or a group represented by formula Q14, X 1 represents a 9- or 10-membered aromatic heterocyclic group optionally substituted by one or more substituents selected from group A, When Q is a group represented by formula Q5, X 1 represents a 9-membered aromatic heterocyclic group which may be substituted with one or more substituents selected from group A. Group A: C1-C6 chain hydrocarbon group {the C1-C6 chain hydrocarbon group may be substituted with one or more substituents selected from the group consisting of a C3-C6 cycloalkyl group which may be substituted with one or more halogen atoms, a halogen atom, and a cyano group}, a C3-C6 cycloalkyl group {the C3-C6 cycloalkyl group may be substituted with one or more substituents selected from the group consisting of a halogen atom, a C1-C6 alkoxy group, and a cyano group}, a phenyl group which may be substituted with one or more substituents selected from Group B, a 5- or 6-membered aromatic heterocyclic group which may be substituted with one or more substituents selected from Group B, OR 3a , S.F. 5 , N.R. 3d OR 3b , N.R. 3b C(O)R 3c , N.R. 3d N.R. 3b C(O)R 3c , N.R. 3b C(O)OR 3e , N.R. 3d N.R. 3b C(O)OR 3e , N.R. 3b C(O)NR 3f R 3g , N.R. 3d N.R. 3b C(O)NR 3f R 3g , N=S(O) q R 3h R 3i , C(O)R 3c , C(O)OR 3j , C(O)NR 3f R 3g , S(O) 2 N.R. 3f R 3g , N.R. 3b C (=NOR 3j ) R 3d , N.R. 3b S (O) 2 R 3k , S(O) r R 3k The group consisting of a cyano group, a nitro group, and a halogen atom. R 3a represents a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group {the C3-C6 cycloalkyl group may be substituted with one or more substituents selected from the group consisting of halogen atoms and cyano groups}, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, C(O)R 3c , C(O)OR 3j , C(O)NR 3f R 3g , S(O) 2 R 3k or a hydrogen atom, R 31a , R 32a , and R 33a are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group {the C3-C6 cycloalkyl group may be substituted with one or more substituents selected from the group consisting of a halogen atom and a cyano group}, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, C(O)R 3c , C(O)OR 3j , C(O)NR 3f R 3g or a hydrogen atom, R 3b , R 31b , R 3d , R 31d , R 3f , R 31f , and R 32f are the same or different and each represents a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, or a hydrogen atom; R 3c , R 31c , and R 32c are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, or a hydrogen atom, R 3e , and R 31e are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, a (C3-C6 cycloalkyl)C1-C3 alkyl group optionally substituted with one or more halogen atoms, or a phenyl C1-C3 alkyl group {the phenyl moiety in the phenyl C1-C3 alkyl group may be substituted with one or more substituents selected from group B}, R 3g , R 31g , and R 32g are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, or a hydrogen atom, R 3h represents a C1-C6 alkyl group optionally substituted by one or more halogen atoms, a phenyl group optionally substituted by one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted by one or more substituents selected from group B, or a C3-C6 cycloalkyl group optionally substituted by one or more halogen atoms, R 3i , and R 31i are the same or different and represent a C1-C6 alkyl group optionally substituted with one or more halogen atoms, or a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, R 3j , R 31j , and R 32j are the same or different and represent a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a phenyl group optionally substituted with one or more substituents selected from group B, or a hydrogen atom; R 3k represents a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a phenyl group optionally substituted with one or more substituents selected from group B, or a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, q represents 0 or 1; r represents 0, 1, or 2. Group B: a group consisting of a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, a C3-C6 cycloalkyl group optionally substituted with one or more halogen atoms, a C1-C6 alkoxy group optionally substituted with one or more halogen atoms, a cyano group, a halogen atom, and a hydroxy group. Group C: a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, OR 31a , N.R. 31b C(O)R 31c , N.R. 31d N.R. 31b C(O)R 31c , N.R. 31b C(O)OR 31e , N.R. 31d N.R. 31b C(O)OR 31e , N.R. 31b C(O)NR 31f R 31g , N.R. 31d N.R. 31b C(O)NR 31f R 31g , N=S(O) q R 3h R 31i , C(O)R 31c , C(O)OR 31j , C(O)NR 31f R 31g , S(O) r R 3k The group consisting of a cyano group, a nitro group, and a halogen atom. Group E: a C1-C6 chain hydrocarbon group optionally substituted with one or more halogen atoms, OR 32a , S(O) m R 3k The group consisting of halogen atoms, oxo groups, and cyano groups. Group F: a C3-C6 cycloalkyl group optionally substituted with one or more substituents selected from group E, a phenyl group optionally substituted with one or more substituents selected from group B, a 5- or 6-membered aromatic heterocyclic group optionally substituted with one or more substituents selected from group B, OR 33a , S(O) r R 3k , C(O)R 32c , C(O)OR 32j , C(O)NR 32f R 32g the group consisting of a 3- to 6-membered non-aromatic heterocyclic group, a cyano group, and a halogen atom. or an N-oxide thereof, or a salt thereof to harmful arthropods, a habitat of harmful arthropods, a plant, or a cultivation carrier of a plant.
2. 2. The method for controlling arthropod pests according to claim 1, wherein the cultivation carrier for the plant is soil.
3. A composition comprising the compound represented by formula (I) according to claim 1 or an N-oxide thereof, or a salt thereof, and one or more components selected from the group consisting of group (a), group (b), group (c), group (d), group (e), group (f), group (g), group (h), group (i) and group (j): Group (a): A group consisting of insecticidal active ingredients, acaricidal active ingredients and nematicidal active ingredients; Group (b): bactericidal active ingredient; Group (c): plant growth regulating ingredients; Group (d): phytotoxicity-safening components; Group (e): synergists; Group (f): repellent components; Group (g): molluscicidal components; Group (h): insect pheromones; Group (i): herbicidal active ingredients; Group (j): biological control materials.
4. A method for controlling arthropod pests, which comprises the step of applying an effective amount of the composition according to claim 3 to arthropod pests, their habitats, plants, or cultivation carriers for plants.
5. The method for controlling arthropod pests according to claim 4, wherein the support for cultivating plants is soil.
6. A seed or vegetative reproductive organ carrying an effective amount of a compound of formula (I) or an N-oxide thereof or a salt thereof as defined in claim 1, or a composition as defined in claim 3.
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Quinazoline derivative or its salt and pharmaceutical composition comprising the same
WO2017188720A2