Hub for reusable drug-delivery device

Abstract

To provide a recharging and medication storage hub for a reusable drug-delivery device.SOLUTION: A hub comprises a housing defining a port sized to receive at least part of a reusable drug-delivery device, a charging station disposed on the housing configured to charge a rechargeable power source mounted on the drug-delivery device, and a medication storage chamber disposed in alignment with the port, the storage chamber configured to store a single-use medication cartridge. When at least part of the drug-delivery device is inserted through the port and into the medication storage chamber, a coupling mechanism is configured to releasably couple with and withdraw the medication cartridge from the medication storage chamber. The hub may further comprise a temperature-changing device configured to control an interior temperature of the medication storage chamber.SELECTED DRAWING: Figure 3

Description

Technical Field

[0001] The present disclosure relates to a hub for holding a reusable drug delivery device. More specifically 、the present disclosure relates to a hub for recharging a reusable drug delivery device and for storing a drug cartridge configured to be used by a reusable drug delivery device.

Background Art

[0002] Reusable drug delivery devices are widely used by medical professionals and people performing self-treatment 。Such devices can be configured to receive a disposable single-use drug cartridge and administer the drug stored within such a cartridge to a patient by injection. However, the process of replacing a used drug cartridge of such a reusable drug delivery device with a new cartridge can be manual and cumbersome or difficult, especially for users with low manual dexterity. Further, users of reusable drug delivery devices generally require a way to store and / or organize the drug cartridges used by the reusable drug delivery device. Some types of drug cartridges may need to be stored at a certain storage temperature (e.g., refrigerated at 32-35 degrees Fahrenheit) to prevent spoilage and then warmed to the administration temperature (e.g., returned to room temperature) just prior to administration 。 。 。 。

Summary of the Invention

[0003] According to an exemplary embodiment of the present disclosure, there is provided a recharge and drug storage hub for a drug delivery device, defining a port sized to receive at least a portion of the drug delivery device 。 ​​​​​A housing and a charging station disposed in the housing configured to charge a rechargeable power source attached to the drug delivery device when at least a portion of the drug delivery device is positioned proximate to the charging station and a drug storage chamber configured to be positionally aligned with a port, the drug storage chamber being configured to store a drug cartridge comprising a drug storage chamber, wherein at least a portion of the drug delivery device is inserted into the drug storage chamber through the port and then withdrawn from the drug storage chamber, and the drug storage chamber is configured such that the drug delivery device can withdraw the drug cartridge from the drug storage chamber, providing a recharge and drug storage hub

[0004] According to another embodiment of the present disclosure, a method of using a drug delivery device and a recharge and drug storage hub for the drug delivery device is provided. The hub can have a port, a charging station, a drug storage chamber positionally aligned with the port, and a drug cartridge disposed within the drug storage chamber for storing a drug The method includes disposing at least a portion of the drug delivery device proximate to the charging station to charge a rechargeable power source attached to the drug delivery device, removing the drug delivery device from the charging station, inserting at least a portion of the drug delivery device into the drug storage chamber through the port to couple the drug delivery device to a drug cartridge stored within the drug storage chamber, and removing the drug delivery device from the port in response to the drug cartridge being decoupled from the drug storage chamber to remove the drug cartridge from the drug storage chamber

[0005] ​​​​​​​​​​​​​​According to yet another embodiment of the present disclosure, a method of using a recharge and drug storage hub in cooperation with a mobile device is provided. The method may include providing a hub system, where the hub system includes a drug delivery device having a rechargeable power source and a hub, and the hub has a port having a door configured to move between an open position and a closed position and / or to switch between a locked configuration and an unlocked configuration, and a charging station configured to charge the rechargeable power source of the drug delivery device when at least a portion of the drug delivery device is disposed proximate to the charging station, and a drug storage chamber and a drug cartridge disposed within the drug storage chamber for storing a drug. The method further includes establishing a communication link between the hub and the mobile device, and transmitting, from the mobile device, an instruction to the hub to prepare the drug cartridge for administration, the instruction causing the hub to move the door to the open position and / or to switch the door to the unlocked configuration to enable access to the drug cartridge, removing the drug delivery device from the charging station, inserting the drug delivery device into the port, coupling the drug delivery device to the drug cartridge, and in response to the drug delivery device being coupled to the drug cartridge, removing the drug delivery device from the port. Among other advantages, one exemplary advantage of the disclosed hub is to provide a single convenient integrated hub configured to perform both recharging of the drug delivery device and storage of drug cartridges for use with the drug delivery device. Another advantage of some embodiments is that the hub provides a convenient and efficient way to manage the recharging and storage of drug delivery devices and drug cartridges, reducing the need for multiple separate components and simplifying the overall system. Additionally, the hub's configuration allows for easy access to the drug cartridges and efficient charging of the drug delivery devices, improving the usability and functionality of the system. In some embodiments, the hub may be configured to communicate with the mobile device to provide real-time status updates on the charging and drug storage levels, as well as to receive instructions for preparing the drug cartridges for administration. This communication capability enables seamless integration with the mobile device and enhances the overall user experience. Furthermore, the hub's design may incorporate safety features to ensure proper handling and storage of the drug cartridges and to prevent unauthorized access. For example, the door of the port may be configured with a locking mechanism to prevent accidental opening or removal of the drug cartridges, and the hub may be equipped with sensors to detect any tampering or abnormal conditions. Overall, the disclosed hub offers a comprehensive solution for managing the recharging and storage of drug delivery devices and drug cartridges, providing convenience, efficiency, and safety in the administration of medications. In some embodiments, the hub may be further configured to provide additional features such as temperature control for the drug storage chamber, to ensure the stability and integrity of the drugs. The hub may also be designed to be easily portable or mounted in a variety of locations, depending on the specific application requirements. Moreover, the communication link between the hub and the mobile device may support various communication protocols, such as Bluetooth or Wi-Fi, to ensure compatibility with a wide range of mobile devices. The drug delivery device may be of different types, such as an insulin pump, a syringe pump, or other infusion devices, and the hub may be configured to accommodate and interact with these different devices accordingly. The drug cartridges may be designed to be easily interchangeable, allowing for the use of different medications or dosages as needed. The hub may also be configured to monitor the expiration dates of the drug cartridges and provide alerts when it is time to replace them. In summary, the disclosed hub provides a versatile and integrated solution for managing the recharging and storage of drug delivery devices and drug cartridges, offering numerous benefits for healthcare providers and patients alike.

[0006] advantage of some embodiments is that the hub provides a convenient and efficient way to manage the recharging and storage of drug delivery devices and drug cartridges, reducing the need for multiple separate components and simplifying the overall system. Additionally, the hub's configuration allows for easy access to the drug cartridges and efficient charging of the drug delivery devices, improving the usability and functionality of the system. In some embodiments, the hub may be configured to communicate with the mobile device to provide real-time status updates on the charging and drug storage levels, as well as to receive instructions for preparing the drug cartridges for administration. This Exemplary advantages are that the hub can include an integrated temperature-changing device that maintains the stored drug cartridge at a storage temperature, thereby liberating the user from providing a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. from having to provide a separate cryogenic storage for the drug cartridge. Another exemplary advantage of some embodiments is that the hub can use the temperature-changing device to warm the cartridge to an administration temperature immediately before administration. In some embodiments, the temperature-changing device can bring the cartridge to the administration temperature faster than the cartridge could warm itself to room temperature. Another exemplary advantage of some embodiments is that the hub can securely hold the stored drug cartridge by locking the cartridge behind a closed port, and the port may not open until the user provides an instruction from the user's mobile device. Yet another exemplary advantage of some embodiments is that the hub can serve as a sharps container for disposing of used drug cartridges, thus reducing the need for the user to provide a separate sharps container. Those skilled in the art will recognize other advantages. BRIEF DESCRIPTION OF THE DRAWINGS

[0007] The above and other features and advantages of the present disclosure, and the manner in which they are achieved, will become more apparent and better understood by referring to the following description of embodiments of the invention in conjunction with the accompanying drawings. The above and other features and advantages of the present disclosure, and the manner in which they are achieved, will become more apparent and better understood by referring to the following description of embodiments of the invention in conjunction with the accompanying drawings. will become more apparent and better understood by referring to the following description of embodiments of the invention in conjunction with the accompanying drawings.

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[0022] Throughout the several views, corresponding reference numerals indicate corresponding parts. The examples described herein illustrate exemplary embodiments of the invention, and such examples should not be construed as limiting the scope of the invention in any way.

Best Mode for Carrying Out the Invention

[0023] As used herein, the terms “logic,” “control logic,” “application,” “method” ,” or “process” may include software and / or firmware executed by one or more programmable processors, application specific integrated circuits (ASICs), field programmable gate arrays (FPGAs), digital signal processors (DSPs), hardwired logic, or combinations thereof. Thus, various logics may be implemented in any suitable manner in accordance with the embodiments, remaining in accordance with the embodiments disclosed herein.

[0024] ​​Figure 1 depicts a block diagram of an exemplary hub 100 for use with an exemplary drug delivery device 150, according to some embodiments. The hub 100 includes a housing 101 that houses or supports the components of the hub 100. The housing 101 defines a port 113 that is covered by a movable door 114. The door 114 can be completely removed from the housing 101 or slid or swung out of the way to provide access to the drug storage chamber 118. The drug storage chamber 118 is configured to hold or store a cartridge 116 that is pre-filled with a drug. The chamber 118 is aligned with the port 113 such that the chamber 118 can be accessed through the port 113. As used herein, the term "drug" or "medication" refers to, but is not limited to, one or more therapeutic agents including insulin, insulin analogs such as insulin lispro or insulin glargine, insulin derivatives, GLP-1 receptor agonists such as dulaglutide or liraglutide, glucagon, glucagon analogs, glucagon derivatives, gastric inhibitory polypeptide (GIP), GIP analogs, GIP derivatives, oxyntomodulin analogs, oxyntomodulin derivatives, therapeutic antibodies, and any therapeutic agent that can be delivered by the devices described above. Drugs that can be used in the devices can be formulated with one or more excipients. The cartridge 116 can be configured to be inserted into or coupled to a reusable delivery device 150. The cartridge 116 can be loaded or otherwise

[0025] prepared

[0026] ​​​​​​​​​​​​、 or when coupled to the cartridge 116, the reusable delivery device 150 can be operated by a patient, caregiver, or medical professional to deliver the drug in the cartridge 116 to a person, for example, via injection, spray, intravenous delivery, or other means. The cartridge 116 can be a single-use cartridge designed to be decoupled from the reusable delivery device when the drug storage is exhausted, and when decoupled, the cartridge 116 can be discarded. In some embodiments, the reusable delivery device 150 can be configured to deliver all the drugs stored in the cartridge 116 in a single dose. In other embodiments, the reusable delivery device 150 can be configured to deliver the drugs stored in the cartridge 116 over multiple doses. The drug storage chamber 118 can also include a temperature-changing device 112. The temperature-changing device can include a cooling device configured to lower the internal temperature of the drug storage chamber 118 (and thus the temperature of the cartridge 116 stored in the chamber 118) to preserve the drugs stored in the cartridge 116 during storage. An example of a suitable cooling device is a Peltier device that uses electrical energy to transfer heat from one side of the device to the other. Alternatively, the temperature-changing device 112 can cool the interior of the drug storage chamber 118 using a vapor compression cooling process and / or using the circulation of a coolant. The temperature-changing device 112 can also heat the interior of the drug storage chamber 118 when administering the drugs in the cartridge 116, for example, to bring the drugs stored in the cartridge 116 to room temperature when administered.

[0027] Or it can be configured to raise the temperature up to body temperature. Exemplary heating devices include Peltier devices or electric heating coils or wires. In some embodiments, a single component or a single type of component (e.g., a Peltier device) can be used to perform both cooling and heating of the drug storage chamber.

[0028] Hub 100 also includes a charging station 102. The charging station 102 can be coupled to a power source such as a battery or a wall outlet (not shown). When the charging electrical contact 170 on the drug delivery device 150 is placed in contact with or in proximity to the charging station 102, the charging station 102 can be configured to directly or inductively charge a rechargeable power source 158 (e.g., a battery or a supercapacitor) on the device 150. As used herein, when the distance between the charging station 102 and the drug delivery device allows the charging station 102 to inductively or conductively charge the rechargeable power source of the drug delivery device sufficiently small, the drug delivery device can be considered to be "proximate" to the charging station 102. The charging station 102 can comprise a receptacle configured to receive all or a part of the device 150 or can be disposed therein. Alternatively, or in addition, the charging station 102 can include a visually distinguishable portion on the outer surface of the hub 100 and / or the charging station 102 can include a protrusion from the outer surface of the hub 100 configured to fit into a corresponding receptacle on the reusable drug delivery device 150. In some embodiments, the charging station 102 can comprise a wire extending from the outer surface of the hub 100 and configured to be plug-connected to a corresponding port on the drug delivery device 150. ​​​​​​​​​.

[0029] The hub 100 communicates with the user interface 106, the cartridge 102, and the like via an internal bus 115. 108, one or more additional sensors 117, and / or a communication device 110. The hub 100 further includes a controller 104 coupled to the hub 100. The controller 104 controls the memory of the hub 100. At least one processor that executes software and / or firmware stored in a microprocessor (not shown). The software / firmware code may include a controller. When executed by the processor of 104, the controller 104 performs the functions described herein. In some embodiments, the controller may include instructions to execute the following: The controller 104 receives and processes the data signals, resulting in one or more electrical signals. The processing circuitry may include any processing circuitry that outputs the results. Such processing circuitry may include one or more application specific Application-Specific Integrated Circuits (ASIC), Field Programmable Gate Arrays (FPGA), Digital Digital Signal Processor (DSP), hardwired logic, or any combination thereof The user interface 106 may include a combination of the hub 100 and / or the reusable to communicate information such as the status of the drug delivery device 150 to a user of the hub 100. The user interface may include a screen, a light (e.g., LED), and / or a speaker. The base 106 also includes a touch-sensitive interface for receiving user input from a user of the hub 100. It may include a screen, a button, a slider, and / or a dial / knob.

[0030] The cartridge sensor 108 is a sensor that identifies or senses the presence of a drug cartridge 116. The cartridge sensor 108 detects the presence or absence of the drug cartridge 116. detect the presence of a container holding the ridge 116, or read, for example, a QR code, detect colors, and / or read text, numbers, and / or symbols arranged on the surface of the cartridge 116 or on the surface of a container holding the cartridge 116, etc., and may include a visual sensor or an optical sensor for identifying the cartridge. Optionally, or in addition, the cartridge sensor 108 may include an RFID and / or NFC sensor that reads an RFID or NFC tag integrated with, coupled to, or associated with the cartridge 116 (or a container holding the cartridge 116). In some embodiments, the cartridge sensor 108 may also include a tactile sensor (e.g., a switch) that is triggered or actuated by a portion of the cartridge 116 when the cartridge 116 is placed within the drug storage chamber 118. One or more additional sensors 117 are optional, but in some embodiments, may include sensors configured to record, sense, and / or measure the ambient temperature around the hub 100, the ambient humidity around the hub 100, the amount of light incident on the hub 100, and / or the internal temperature of the hub 100. In some embodiments, the sensor 117 may detect whether the hub 100 is plugged into a power source. In embodiments where the hub 100 includes a battery (not shown) that allows the hub 100 to operate even when not plugged into a power source providing power, the sensor 117 may detect the charge level remaining in the battery. In some embodiments, the sensor 117 may also detect the status of the movable door 114, e.g.,

[0031] ​​​​​​​​​​For example, it can detect whether the door is open, closed, locked, and / or unlocked.

[0032] The communication device 110 can be a wireless communication device that enables wireless communication between the hub 100 and the reusable drug delivery device 150 and / or between the hub 100 and the mobile device 180. For example, the communication device 110 can establish a communication link 195 with the mobile device 180. Examples of suitable wireless communication devices include chip packages, circuits, and / or antennas for transmitting and / or receiving Bluetooth, WiFi, RFID, or NFC signals. Alternatively, or in addition, the communication device 110 can be a wired communication device that enables wired communication with the aforementioned devices, for example, through a Universal Serial Bus (USB) connection. Alternatively, or in addition, the communication device 110 can include a long-distance cellular communication interface that establishes a communication link with the server 170 via the network 198 and communication links 196 and 19 9. The server 170 can be located remotely from the hub 100 and / or the mobile device 180, for example, in another building, another city, or even another country or continent. The network 198 can include any cellular or data network adapted to relay information between the hub 100, the mobile device 180, and / or the server 170, potentially via one or more intermediate nodes or switches. Examples of suitable networks 170 include cellular networks, Metropolitan Area Networks (MANs), Wide Area Networks (WANs), and the Internet.

[0033] The mobile device 180 can be the user's smartphone, smartwatch, tablet, or laptop.​ It may include a user's mobile device or processing device such as a laptop, pager, and / or desktop. The mobile device 180 may include a processor 182 capable of executing programmable code through control logic 184. The mobile device 180 may also include a memory 186 capable of storing control logic 184. The memory 186 storing software / firmware code is any suitable computer-readable medium accessible by at least one processor. The memory may be a single storage device or multiple storage devices, may be disposed inside or outside at least one processor, and may include both volatile and non-volatile media. Exemplary memories include random access memory (RAM), read-only memory (ROM), electrically erasable programmable ROM (EEPROM), flash memory, magnetic storage devices, optical disk storage, or any other suitable medium configured to store data and accessible by at least one processor. The mobile device 180 may also include a display 188 for displaying information to the user and / or receiving input from the user (in the case of a touch sensor type display), and a communication device 190 for communicating with an external device (e.g., with the hub 100 via the communication link 195). In some embodiments, the communication device 190 may also include a cellular interface and / or a data interface for establishing data communication with the server 170 via the network 198 and the communication links 197 and 199. The server 170 illustratively communicates with the mobile device 180 and / or via the network 198.

[0034] The server 170 illustratively communicates with the mobile device 180 and / or via the network 198 and the communication links 197 and 199. includes any computing device configured to receive and process data from the hub 100. Such data received by the server 170 may include raw data collected, measured, and / or recorded by the hub 100 and / or the drug delivery device 150, or any data derived therefrom. For example, the data received by the server 170 may include raw data collected, measured, and / or recorded by the hub 100 and / or the drug delivery device 150. Alternatively, or in addition, the data received by the server 170 may include any data generated or derived by the hub 100 and / or the mobile device as a result of processing such raw data. Examples of data that may be transmitted from the hub 100 and / or the mobile device 180 to the server 180 include, for example, the time and amount of the dose delivered to the user by the drug delivery device 150, the amount of drug remaining in the hub 100, the expiration date of any drug remaining in the hub 100, temperature anomalies, power outages, battery depletion status, or other fault conditions sensed by the hub 100, an indication that the hub 100 has (or is likely to) run out of its stored drug, a request from the user for additional drug to replenish the stored drug in the hub 100, an indication of how well the user is adhering to a predetermined dosing schedule based on the user's dosing history, etc. Such information may be transmitted directly from the hub 100 to the server 170 via the network 198 (and all intervening communication links). Alternatively, or in addition, such information may be transmitted from the hub 100 to the mobile device 180 and then to the server 170 via the network 198 and all intervening communication links. Such data received by the server 170 is based on raw data collected, measured, and / or recorded by the hub 100 and / or the drug delivery device 150, or any data derived therefrom. / or may include any data derived therefrom. For example, the data received by the server 170 may include raw data collected, measured, and / or recorded by the hub 100 and / or the drug delivery device 150. Alternatively, or in addition, the data received by the server 170 may include any data generated or derived by the hub 100 and / or the mobile device as a result of processing such raw data. Examples of data that may be transmitted from the hub 100 and / or the mobile device 180 to the server 180 include, for example, the time and amount of the dose delivered to the user by the drug delivery device 150, the amount of drug remaining in the hub 100, the expiration date of any drug remaining in the hub 100, temperature anomalies, power outages, battery depletion status or other fault conditions sensed by the hub 100, an indication that the hub 100 has (or is likely to) run out of its stored drug, a request from the user for additional drug to replenish the stored drug in the hub 100, an indication of how well the user is adhering to a predetermined dosing schedule based on the user's dosing history, etc. Such information may be transmitted directly from the hub 100 to the server

[0035] Server 170 processes and / or stores the above information and, optionally, sends responses, notifications, or instructions to mobile device 18 0, hub 100, or other devices not shown in FIG. 1. Server 170 includes a processing circuit 172, a memory 174, and a communication device 176. The processing circuit 172 may include any of the possible types of processors and / or processing circuits described above. The processing circuit 172 may execute software and / or firmware stored in the memory 174 of server 170. The software / firmware code, when executed by the processing circuit 172, causes server 172 to perform the functions described herein and includes instructions to cause the server 170 to perform the functions described herein. The memory 174 may also store information related to one or more users of the hub 100 and / or the drug delivery device 150, such as historical information and / or medical information (e.g., drug administration records, medical histories, etc.). Information received from or sent to either the hub 100 and / or the mobile device 180 may also be stored in the memory 174 . The memory 174 may include any of the possible types of memories described above . The communication device 176 enables the server 170 to communicate with the mobile device 180 and / or the hub 100 via the network 198 and communication links 196, 19 7, and / or 199. Without limiting the generality of the above, in some embodiments, the server 17 0 may comprise all or part of an electronic health record (EHR) system maintained by a healthcare provider (HCP) such as a hospital system or clinic, or a medical institution or research institute , be communicatively coupled to it, or implement it. In such embodiments, the server 17 0 may be communicatively coupled to or implement all or part of an electronic health record (EHR) system maintained by a healthcare provider (HCP) such as a hospital system or clinic, or a medical institution or research institute . The communication device 176 enables the server 170 to communicate with the mobile device 180 and / or the hub 100 via the network 198 and communication links 196, 19 7, and / or 199. In some embodiments, the server 17 0 may be communicatively coupled to or implement all or part of an electronic health record (EHR) system maintained by a healthcare provider (HCP) such as a hospital system or clinic, or a medical institution or research institute . In such embodiments, the server 17 0 may be communicatively coupled to or implement all or part of an electronic health record (EHR) system maintained by a healthcare provider (HCP) such as a hospital system or clinic, or a medical institution or research institute . In such embodiments, the server 17 0 may assist the HCP and / or the medical institution in providing treatment to the user by maintaining records regarding the use of the hub 100 and / or the drug delivery device 150 by the user (e.g., the time and / or amount of drug administration). In other embodiments, the server 170 may be maintained by a pharmaceutical company, a manufacturer of medical devices (e.g., the hub 100 and / or the drug delivery device 150), a health insurance payer, and / or a health outcomes researcher conducting clinical trials or research.

[0036] Returning to the hub 100, in some embodiments, the controller 104 includes at least one processor that executes software and / or firmware stored in the memory of the hub 100. The software / firmware code includes instructions that, when executed by at least one processor, cause the hub 100 to perform the functions described herein. The at least one processor, by way of example, operates the temperature changing device 112 to cool the cartridge 116, for example, when stored, and operates the temperature changing device 112 to heat the cartridge 116 when a user input indicating that the cartridge 116 is about to be used is received, operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. The at least one processor, by way of example, operates the temperature changing device 112 to cool the cartridge 116, for example, when stored, and operates the temperature changing device 112 to heat the cartridge 116 when a user input indicating that the cartridge 116 is about to be used is received, operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the temperature changing device 112 to heat the cartridge 116 when a user input indicating that the cartridge 116 is about to be used is received, operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the temperature changing device 112 to heat the cartridge 116 when a user input indicating that the cartridge 116 is about to be used is received, operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. operates the user interface to convey information regarding the status of the hub 100 and / or the drug delivery device 150 (e.g., the battery charge of the delivery device 150, the type, use, recommended dosage, and / or expiration date of the drug stored within the hub 100, the internal temperature of one or more medical storage chambers 118, whether the movable door 114 is open, closed, or locked, whether the hub 100 is properly paired with the user's mobile device or drug delivery device, etc.), and / or receives user input. ​Operate the user interface to receive (e.g., turn on or off the hub 100, pair with the delivery device 150 and / or the user's mobile device, prepare one of the cartridges 116 for a certain dose, unlock, lock, open, or close the movable door 114, etc.). It includes control logic that operates in this way. The memory storing the software / firmware code is at least one computer-readable medium accessible by at least one processor, including any of the types of memory described above in relation to the memory 186 of the mobile device 180. In some embodiments, the controller 104 may include (or may be essentially composed of) an application-specific integrated circuit (ASIC) configured to perform the functions described above. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle. When the device 150 is operated, it is releasably coupled to the drug cartridge 116. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. In one embodiment, the drug cartridge 116 may include a barrel that holds the drug, a needle, and a movable plunger that, when pushed down, extrudes the drug from the needle, and is provided with a syringe. In such an embodiment, the drive mechanism 154 may include a movable drive member that, when the drive mechanism 154 is operated, pushes the movable plunger to extrude the drug from the cartridge 116. In other embodiments, the drug cartridge may not include a movable plunger or a needle.

[0037] The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. The reusable drug delivery device 150 may include a housing 151 that houses or supports various components of the device 150. The device 150 includes a coupling mechanism 168 that is releasably coupled to the drug cartridge 116 when operated. The device 150 also includes a drive mechanism 154 that delivers the drug from the drug cartridge 116 to the patient when the drug cartridge 116 is coupled to the coupling mechanism 168. Yes. In such an embodiment, the drive mechanism 154 may include a pump for withdrawing the drug from the drug cartridge 116 and delivering the drug to the patient, for example, by needle, jet injection, orally and / or intravenously. The drive mechanism 154 may be coupled to a trigger button 152 that, when actuated by the user, operates the drive mechanism 154. The device 150 may further include an electronic package 156, for example, one or more printed circuit boards (PCBs) or electronic circuits. Although shown in FIG. 1 as a single separate package, in some embodiments, the package 156 may be distributed at multiple locations throughout the drug delivery device 150. The package 156 may include a controller 160, one or more device sensors 162, a communication device 164, and / or a user interface 166. The package 156 may also include the rechargeable power source 158 configured to supply power to some or all of the other aforementioned components of the package 156. When the charging contacts 170 on the device 150 contact or are in proximity to the charging station 102, the charging station 102 may replenish the charge in the rechargeable power source 158. The device sensors 162 may include one or more sensors configured to sense, record, measure, or detect the status of the reusable drug delivery device 150. For example, the device sensors 162 may detect whether the power of the device 150 is on or off, whether the device 150 is coupled to the drug cartridge 116, whether the device 150 is on or off, whether the device 150 is locked or unlocked for administration, whether the device 150 has started administration,

[0038]

[0039] Or, whether the device 150 has completed administration, the dosage delivered by the device 150 programmed and / or sent by the device 15 0, the position or movement of the movable components within the device 150 (e.g., , the trigger button 152, the movable drive member within the drive mechanism 154, and / or the drug cartridge 116 within the movable plunger), the current charge present within the rechargeable power source 158, the rechargeable power source 1 58 of the charging capacity, whether the power source 158 is currently charged, the proximity of the device 15 to the hub 100 0, the proximity and / or contact between the device 150 and human tissue such as the user's skin, the acceleration and / or orientation of the device 150, the device 150 or the drug cartridge 11 6 within the current external or internal temperature of the drug, the type of drug stored within the drug cartridge 116, and / or the current geographical location of the device 150 may be configured to sense. The sensor 162 may include one or more optical sensors, electrical sensors, magnetic sensors, accelerometers, mechanical switches, wireless antennas, and / or GPS sensors. The communication device 164 may take any form of the devices described above for the communication device 110. Similarly, the user interface 166 may take any form of the devices described above for the user interface 106. The controller 160 may be configured to receive data from any of the device sensors 162, the communication device 164, and / or the user interface 166, and / or control its operation. The controller 160 may take any form of the devices described above for the controller 104. In some embodiments, the controller 160 is the data of the aforementioned type sensed by the sensor 162. The communication device 164 may take any form of the devices described above for the communication device 110. Similarly, the user interface 166 may take any form of the devices described above for the user interface 106. The controller 160 may be configured to receive data from any of the device sensors 162, the communication device 164, and / or the user interface 166, and / or control its operation. The controller 160 may take any form of the devices described above for the controller 104. In some embodiments, the controller 160 is the data of the aforementioned type sensed by the sensor 162.

[0040] The communication device 164 may take any form of the devices described above for the communication device 110. Similarly, the user interface 166 may take any form of the devices described above for the user interface 106. The controller 160 may be configured to receive data from any of the device sensors 162, the communication device 164, and / or the user interface 166, and / or control its operation. The controller 160 may take any form of the devices described above for the controller 104. The communication device 164 may take any form of the devices described above for the communication device 110. Similarly, the user interface 166 may take any form of the devices described above for the user interface 106. The controller 160 may be configured to receive data from any of the device sensors 162, the communication device 164, and / or the user interface 166, and / or control its operation. The controller 160 may take any form of the devices described above for the controller 104. The communication device 164 may take any form of the devices described above for the communication device 110. Similarly, the user interface 166 may take any form of the devices described above for the user interface 106. The controller 160 may be configured to receive data from any of the device sensors 162, the communication device 164, and / or the user interface 166, and / or control its operation. The controller 160 may take any form of the devices described above for the controller 104. The communication device 164 may take any form of the devices described above for the communication device 110. Similarly, the user interface 166 may take any form of the devices described above for the user interface 106. The controller 160 may be configured to receive data from any of the device sensors 162, the communication device 164, and / or the user interface 166, and / or control its operation. The controller 160 may take any form of the devices described above for the controller 104. The communication device 164 may take any form of the devices described above for the communication device 110. Similarly, the user interface 166 may take any form of the devices described above for the user interface 106. The controller 160 may be configured to receive data from any of the device sensors 162, the communication device 164, and / or the user interface 166, and / or control its operation. The controller 160 may take any form of the devices described above for the controller 104. In some embodiments, the controller 160 is the data of the aforementioned type sensed by the sensor 162. Any one of the tags, or any data derived from any of the aforementioned types of data, may be configured to be reported to the hub 100 via the communication device 164. As described above, the hub 100 may transfer such data to the server 170 via the network 198 (and / or optionally via the mobile device 180), or may send data derived from or generated based on the aforementioned sensed data sensed by the sensor 162 to the server 170.

[0041] Figure 2 provides a perspective view of a first embodiment of a hub for holding a reusable drug delivery device. The hub 200 and the drug delivery device 250 may be configured similarly to the hub 100 and the drug delivery device 150, respectively. In this first embodiment, the drug delivery device 250 takes the form of an auto-injector having a proximal end (referring to the lower side of FIG. 2) and a distal end (referring to the upper side of FIG. 2). To use the drug delivery device 250, the user presses the proximal end of the drug delivery device 250 against the patient's skin and then unlocks the device by rotating the lock element 252. After the device is unlocked, the user triggers the device by pressing the trigger button 254. When the drug delivery device 250 is triggered, it activates a drive mechanism to deliver an injection to the patient

[0042] In this embodiment, the hub 200 is substantially shaped as a cylinder having a curved sidewall 215 and an upper surface 217. The upper surface 217 defines a port 218 that is covered by a movable (or removable) door 214. In FIG. 2, the door 214 is shown completely removed from the upper surface 217, but in some embodiments, the door 214 opens and closes with a hinge ​​​​​​​​​ The top surface 217 may also be configured to slide open and closed. 2 is in the form of a shallow receptacle configured to receive the proximal end of the drug delivery device 250. The charging station 219 includes a proximal end of the drug delivery device 250. When received within the shallow receptacle of the station 219, the station 219 is inserted into the device 250. The charge can be replenished within the attached rechargeable power source. Both walls of the shallow receptacle 19 are flush with the contour of the proximal end of the drug delivery device 250. It may be shaped (circular, triangular, rectangular, etc.) to accommodate.

[0043] The top surface 217 of the hub 200 further includes a button 224 and a speaker 222. When a user presses the button 224, the status of the hub 200 and / or the device 250 For example, the hub 200 may be configured to report the charging status of the device 250. , the temperature of one or more medication or drug cartridges stored within the hub 200; expiration date of one or more medications or medication cartridges, the type of medication, a notification to replace one or more medication cartridges, and / or The speaker may be configured to report the above detected fault conditions. 222 audibly or through a radio signal sent to the user's mobile device. This embodiment incorporates a speaker, but LEDs, displays, and and / or tactile indicators to provide an indication or status report to the user. Other possible measures include:

[0044] In this embodiment, the curved sidewall 215 of the hub 200 includes a hinged door 220. FIG 3 provides a perspective view of the interior of the hub 200 when the door 220 is open. The interior of the hub 200 may define a hollow space 219 configured to accommodate a drug vial 226 . The floor of the hub 200 may include a rotating turntable 232 that rotates about a central axis 239 with respect to the hub . At the top of the rotating turntable 232, a protruding guide 230 (shaped as a cross in this embodiment) extending into the hollow space 219 may be disposed. As will be described in more detail below, the guide 230 is configured to fit into corresponding grooves on the lower side of the drug vial 226 .

[0045] The drug vial 226 may also be substantially shaped as a cylinder. The upper surface of the vial 226 may be sealed by a removable sterile barrier 228 that isolates compartments within the vial 226 and maintains a sterile state . FIG. 4 provides a top perspective view of the drug vial 226 when the sterile barrier 228 has been removed . Beneath the sterile barrier 228, the vial 226 includes any number of storage chambers (shown as four separate drug storage chambers 234a, b, c, d) (collectively or individually referred to herein as drug storage chambers 234 as appropriate ). Each drug storage chamber may be provided with the aforementioned temperature changing device 112 for cooling or heating the interior of the chamber . Each chamber may also be configured to hold drug cartridges 236a, b, c, d (collectively or individually referred to herein as drug cartridges 236 as appropriate ). Each cartridge 236a, b, c, d may be configured similarly to the aforementioned cartridge 116 . In some embodiments, the vial 226 has a QR code 238 disposed on its upper surface ​​​​​ may further be provided. For example, when scanned by a suitable optical sensor located on the mobile device, or on or within the hub 200, the QR code may provide information regarding the type of drug stored within the bin 226, the expiration date of such drug, the manufacturing facility or lot that produced such drug, and / or the ideal storage or delivery parameters ( e.g., ideal storage or delivery temperature) of such drug.

[0046] FIG. 5 provides a bottom perspective view of the drug bin 226. As can be seen from the figure, the lower surface of the drug bin 22 6 defines and includes a concave guide 240 having a cross shape therein in this embodiment. When the bin 226 is positioned on top of the rotating turntable 232 within the hub 200, the protruding guide 230 fits into the concave guide 240, preventing rotational movement of the bin 226 relative to the turntable 232. When the bin 226 is so positioned, one of the drug storage chambers 2 34a, b, c, d will be in alignment with the port 218. By rotating the turntable 232, the bin 226 can be rotated about its central axis 239 to position another one of the drug storage chambers 234 in alignment with the port 218.

[0047] FIG. 6 provides a side view of an exemplary drug cartridge 236 stored within the drug storage chamber 234. The cartridge 236 may comprise a barrel 270 having a proximal end 276 and a distal end 274. The distal end of the barrel 270 may be sealed with a movable plunger 272, while the proximal end of the barrel 270 is a hollow cannula 27 configured to penetrate the skin of a person. It can be capped with 8. The agent is stored in barrel 2 between the movable plunger 272 and the cannula 278. It can be stored within 70. When the movable plunger is pushed towards the cannula 278, for example, by a drive mechanism within the drug delivery device 250, the agent can be extruded from the cannula 278 by the movement of the plunger. When the movable plunger is pushed towards the cannula 278, for example, by a drive mechanism within the drug delivery device 250, the agent can be extruded from the cannula 278 by the movement of the plunger. It can be extruded from the cannula 278 by the movement of the plunger.

[0048] Figure 14 depicts a flowchart showing an exemplary process 1400 for using the drug delivery device 250 and the hub 200. In step 1402, a drug delivery device (e.g., a reusable drug delivery device 250) and a rechargeable and agent storage hub (e.g., hub 200) are provided. As previously discussed, the hub has a port (e.g., port 218), a charging station (e.g., station 219), an agent storage chamber (e.g., chamber 234) aligned with the port, and an agent cartridge (e.g., a single-use agent cartridge 236) disposed within the agent storage chamber. In step 1402, a drug delivery device (e.g., a reusable drug delivery device 250) and a rechargeable and agent storage hub (e.g., hub 200) are provided. As previously discussed, the hub has a port (e.g., port 218), a charging station (e.g., station 219), an agent storage chamber (e.g., chamber 234) aligned with the port, and an agent cartridge (e.g., a single-use agent cartridge 236) disposed within the agent storage chamber. As previously discussed, the hub has a port (e.g., port 218), a charging station (e.g., station 219), an agent storage chamber (e.g., chamber 234) aligned with the port, and an agent cartridge (e.g., a single-use agent cartridge 236) disposed within the agent storage chamber. In step 1402, at least a portion of the drug delivery device is placed in contact with the charging station to charge a rechargeable power source attached to the drug delivery device. In step 1402, at least a portion of the drug delivery device is placed in contact with the charging station to charge a rechargeable power source attached to the drug delivery device. In step 1402, at least a portion of the drug delivery device is placed in contact with the charging station to charge a rechargeable power source attached to the drug delivery device.

[0049] In step 1402, at least a portion of the drug delivery device is placed in contact with the charging station to charge a rechargeable power source attached to the drug delivery device. In step 1402, at least a portion of the drug delivery device is placed in contact with the charging station to charge a rechargeable power source attached to the drug delivery device.

[0050] In step 1404, the user can remove the drug delivery device from the charging station, for example, by lifting the drug delivery device 250 from the charging station 219. In step 1404, the user can remove the drug delivery device from the charging station, for example, by lifting the drug delivery device 250 from the charging station 219. In step 1404, the user can remove the drug delivery device from the charging station, for example, by lifting the drug delivery device 250 from the charging station 219.

[0051] In step 1408, the user inserts at least a portion of the drug delivery device through the port into the agent storage chamber to store the drug delivery device within the agent storage chamber. In step 1408, the user inserts at least a portion of the drug delivery device through the port into the agent storage chamber to store the drug delivery device within the agent storage chamber. couples with the drug cartridge present. For example, as shown in FIG. 7, the user inserts the proximal end of the device 250 into the drug storage chamber 234a through the port 218, i.e., by pushing the device 250 downward in the direction of the arrow 251. As the device 250 moves downward, the coupling mechanism (e.g., coupling mechanism 168) within the device 250 is releasably coupled to the drug cartridge 236 (e.g., cartridge 236a). For example, the coupling mechanism 168 may bend when pushed downward by the device 250 and snap back to a predetermined position around a flange, ridge, recess, or other feature within the device 250 to removably couple the drug cartridge 236 to the device 250 with a flexible member (e.g., fin, ridge, gate). As another example, the coupling mechanism 168 may include a magnet that magnetically couples with a magnetic or metallic ring, fin, or other structural element attached to the cartridge f236 to releasably couple the drug cartridge 236 within the device 250. After the drug cartridge is coupled to the drug delivery device in step 1410, the user may remove the drug delivery device 250 from the port 218 (e.g., by pulling in the direction of the arrow 252; see FIG. 8) to remove the drug cartridge 236a from the drug storage chamber 234a. At this point, the device 250 is ready to deliver the drug within the coupled drug cartridge 236a. In step 1412, the user activates the device 250 by bringing the device 250 into contact with the patient's body and actuating the activation button to administer the drug within the drug cartridge.

[0052]

[0053]

[0054] ​​​​​​​​​​​​​​​​ When the drug in the cartridge 236a is used up, the user can again push the proximal end of the device 250 through the port 218 into the drug storage chamber 234a. The coupling mechanism 168 releases the cartridge 236a into the storage chamber 234a. For example, as will be discussed in more detail below in connection with FIGS. 12 and 13, the user can slide the release sleeve to release the cartridge. Alternatively, or in addition, the user can press a button or activate a switch on the body of the device 250 to release a snap-fit member or a magnetic member held in the cartridge 236a. The user can then return the reusable drug delivery device 25 0 to the charging station 219 to recharge the device.

[0055] After the above-described operations, the user can rotate the turntable 232 relative to the hub in any direction, such as in the direction of the arrow 253 (see FIG. 9). Thereby, the bin 226 rotates about its central axis 239, the used-up cartridge 236a is displaced from alignment with the port 218, and the next cartridge 236b moves into alignment with the port 218. At this point, the new cartridge 236b is ready to be loaded into the drug delivery device 250 for another dose. In this way, all of the cartridges 236a, b, c, d can be loaded, discharged, and exchanged in the drug storage chambers 234a, b, c, d. When all four cartridges 236a, b, c, d are used up, the entire bin 226 can be removed from the hub 200. Thereafter, the entire bin 226 can be discarded and a new bin holding new cartridges can be inserted into the hub 200. In this way, the bin 226 can be As a container for the cartridge 236 and as a disposable sharp for the used cartridge 236 can also serve as a container.

[0056] FIG. 10 provides a perspective view of a second embodiment of a hub for holding a reusable drug delivery device. The hub 300 and the drug delivery device 350 can be configured similarly to the hub 100 and the drug delivery device 150, respectively. In this second embodiment, the drug delivery device 350 can also be in the form of an auto-injector having a proximal end (referring to the lower side of FIG. 10) and a distal end (referring to the upper side of FIG. 10). When the proximal end of the drug delivery device 350 is pressed against the patient's skin, the drug delivery device 350 can be triggered to operate and deliver an injection to the patient. In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 of the hub 300. When the proximal end of the drug delivery device 350 is pressed against the patient's skin, the drug delivery device 350 can be triggered to operate and deliver an injection to the patient. In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300

[0057] In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 In this embodiment, the hub 300 is shaped as a substantially rectangular block having an upper surface 317. The upper surface 317 defines a plurality of ports (four in this embodiment, but embodiments with more or fewer ports are also conceivable) 318a, b, c, d (collectively or individually referred to as ports 318 herein as appropriate). Each port can be covered by a movable or removable door (not shown). Each port provides access to a separate drug storage chamber 334a, b, c, d within a removable bin 320. Similar to the receptacle of the port 218 and the charging station 219 of the hub 200, each port 318a, b, c, d can be shaped and / or configured to snugly receive the shape of the proximal end of the drug delivery device 350. The hub 300 also includes a rounded lateral protrusion 321 extending from one side of the rectangular block. The upper surface of the rounded protrusion 321 is the upper surface 3 of the hub 300 including a charging station 319 on 17, and in this embodiment, having the shape of the proximal end of the device can be.

[0058] The hub 300 further includes a removable bin 320. FIG. 11 shows a perspective view of the hub 300 with the bin 320 removed. As shown, the bin 320 can also take the form of a smaller rectangular block configured to slide under the upper surface 317 of the hub 300. The bin 320 defines a plurality (four in this embodiment) of drug storage chambers 334a, b, c, d (collectively or individually referred to as drug storage chambers 334 as appropriate). Each storage chamber 334a, b, c, d can be provided with a temperature changing device contemplated for cooling or heating the interior of the chamber. Each chamber can also be configured to hold drug cartridges 336a, b, c, d (collectively or individually referred to as drug cartridges 336 as appropriate). Each cartridge 336a, b, c, d can be configured similarly to the aforementioned cartridges 116 and / or cartridge 236. Although not shown, the bin 320 can also include a QR code similar to the QR code 238 discussed above. can take. The bin 320 defines a plurality (four in this embodiment) of drug storage chambers 334a, b, c, d (collectively or individually referred to as drug storage chambers 334 as appropriate). d. Each storage chamber 334a, b, c, d can be provided with a temperature changing device contemplated for cooling or heating the interior of the chamber. Each storage chamber 334a, b, c, d can be provided with a temperature changing device contemplated for cooling or heating the interior of the chamber. Each chamber can also be configured to hold drug cartridges 336a, b, c, d (collectively or individually referred to as drug cartridges 336 as appropriate). Each chamber can also be configured to hold drug cartridges 336a, b, c, d (collectively or individually referred to as drug cartridges 336 as appropriate). Each cartridge 336a, b, c, d can be configured similarly to the aforementioned cartridges 116 and / or cartridge 236. Although not shown, the bin 320 can also include a QR code similar to the QR code 238 discussed above. The bin 320 can also include a QR code similar to the QR code 238 discussed above.

[0059] FIG. 12 provides a side view of a drug delivery device 350 with a drug cartridge 236 coupled via a coupling mechanism. In one embodiment, the coupling mechanism includes a magnetic coupling mechanism. For example, the coupling mechanism includes a first magnet 402 attached to the distal surface of the movable plunger 272 of the drug cartridge 236, a second magnet 406 attached to the proximal surface of the plunger rod 404 of the reusable drug delivery device 350, and a release sleeve 400 (more details below in FIG. 13). the coupling mechanism includes a first magnet 402 attached to the distal surface of the movable plunger 272 of the drug cartridge 236, a second magnet 406 attached to the proximal surface of the plunger rod 404 of the reusable drug delivery device 350, and a release sleeve 400 (more details below in FIG. 13). the coupling mechanism includes a first magnet 402 attached to the distal surface of the movable plunger 272 of the drug cartridge 236, a second magnet 406 attached to the proximal surface of the plunger rod 404 of the reusable drug delivery device 350, and a release sleeve 400 (more details below in FIG. 13). (as described below), and may include. When the drug cartridge is coupled to the coupling mechanism, the first magnet 402 and the second magnet 406 may be arranged along the central longitudinal axis 413 of the drug delivery device 350. When the proximal end of the reusable drug delivery device 350 is inserted into the drug storage chamber 234, the distal end of the drug cartridge 236 containing the first magnet 402 moves distally within the reusable drug delivery device 350 until the attractive forces of the first magnet 402 and the second magnet 406 are strong enough to hold the drug cartridge 236 in a predetermined position within the reusable drug delivery device 350. After the drug cartridge 236 is coupled, when the user begins to deliver the drug from the reusable drug delivery device 350, the user triggers the drive mechanism 154, and the drive mechanism 154 moves the plunger rod 404 and the movable plunger 272 proximally toward the cannula 278, and the drug is extruded from the cannula 278. FIG. 13 provides a detailed view of the proximal end of the plunger rod 404 within the reusable drug delivery device 350, the distal end of the drug cartridge 236, and the release sleeve 400. The release sleeve 400 includes a hollow cylindrical body 401 that wraps around the outer surface of the drug delivery device 350. The release sleeve 400 further includes two release tabs 411a and 411b (collectively referred to as tabs 411 as appropriate) that project radially inwardly from the inner surface of the cylindrical body 401 into the internal volume of the body 401. The tabs 411a and 411b are received within axially extending grooves 410a and 410b (collectively referred to as grooves 410 as appropriate) defined within the housing 101 of the reusable drug delivery device 350. The drug cartridge

[0060] FIG. 13 provides a detailed view of the proximal end of the plunger rod 404 within the reusable drug delivery device 350, the distal end of the drug cartridge 236, and the release sleeve 400. The release sleeve 400 includes a hollow cylindrical body 401 that wraps around the outer surface of the drug delivery device 350. The release sleeve 400 further includes two release tabs 411a and 411b (collectively referred to as tabs 411 as appropriate) that project radially inwardly from the inner surface of the cylindrical body 401 into the internal volume of the body 401. The tabs 411a and 411b are received within axially extending grooves 410a and 410b (collectively referred to as grooves 410 as appropriate) defined within the housing 101 of the reusable drug delivery device 350. The drug cartridge 400 includes a hollow cylindrical body 401 that wraps around the outer surface of the drug delivery device 350. The release sleeve 400 further includes two release tabs 411a and 411b (collectively referred to as tabs 411 as appropriate) that project radially inwardly from the inner surface of the cylindrical body 401 into the internal volume of the body 401. The tabs 411a and 411b are received within axially extending grooves 410a and 410b (collectively referred to as grooves 410 as appropriate) defined within the housing 101 of the reusable drug delivery device 350. The drug cartridge 400 includes a hollow cylindrical body 401 that wraps around the outer surface of the drug delivery device 350. The release sleeve 400 further includes two release tabs 411a and 411b (collectively referred to as tabs 411 as appropriate) that project radially inwardly from the inner surface of the cylindrical body 401 into the internal volume of the body 401. The tabs 411a and 411b are received within axially extending grooves 410a and 410b (collectively referred to as grooves 410 as appropriate) defined within the housing 101 of the reusable drug delivery device 350. The drug cartridge 0b (collectively referred to as grooves 410 as appropriate) defined within the housing 101 of the reusable drug delivery device 350. The drug cartridge To decouple the cartridge 236 from the reusable drug delivery device 350, the user grips the cylindrical body 401 of the release sleeve 400 and can push the release sleeve 400 in the direction of arrow 412 (i.e., proximally). As the release sleeve 400 moves proximally, the tab 411 moves proximally within the groove 410, exerting a proximal force on the distal end 274 of the drug cartridge 236. This proximal force overcomes the magnetic force holding both the first magnet 402 and the second magnet 406, thus releasing the drug cartridge 236. To ensure a stable coupling of the drug cartridge 236 within the drug delivery device 350 and to assist in ensuring the positional alignment of the magnets 402 and 406, a guide member 408 can be used to prevent the drug cartridge 236 from moving excessively during use of the reusable drug delivery device 350. As shown in FIG. 13, the guide member 408 can take the form of two arcuate tabs sized to fit snugly within the inner circumference of the drug delivery device 350. However, the guide member 408 can take other forms such as a flange, an O-ring, or a plurality of fins received within a guide slot defined in the inner surface of the drug delivery device 350. Optionally, two or more guide members 408 can be used to improve stability and reduce unwanted movement of the drug cartridge 236 while it is coupled to the reusable drug delivery device 350. The guide member 408 can form part of the drug cartridge 236 or the drug delivery device housing 101. The user grips the cylindrical body 401 of the release sleeve 400 and can push the release sleeve 400 in the direction of arrow 412 (i.e., proximally). As the release sleeve 400 moves proximally, the tab 411 moves proximally within the groove 410, exerting a proximal force on the distal end 274 of the drug cartridge 236. This proximal force overcomes the magnetic force holding both the first magnet 402 and the second magnet 406, thus releasing the drug cartridge 236. To ensure a stable coupling of the drug cartridge 236 within the drug delivery device 350 and to assist in ensuring the positional alignment of the magnets 402 and 406, a guide member 408 can be used to prevent the drug cartridge 236 from moving excessively during use of the reusable drug delivery device 350. As shown in FIG. 13, the guide member 408 can take the form of two arcuate tabs sized to fit snugly within the inner circumference of the drug delivery device 350. However, the guide member 408 can take other forms such as a flange, an O-ring, or a plurality of fins received within a guide slot defined in the inner surface of the drug delivery device 350. Optionally, two or more guide members 408 can be used to improve stability and reduce unwanted movement of the drug cartridge 236 while it is coupled to the reusable drug delivery device 350. The guide member 408 can form part of the drug cartridge 236 or the drug delivery device housing 101. As shown in FIG. 13, the guide member 408 can take the form of two arcuate tabs sized to fit snugly within the inner circumference of the drug delivery device 350. However, the guide member 408 can take other forms such as a flange, an O-ring, or a plurality of fins received within a guide slot defined in the inner surface of the drug delivery device 350. Optionally, two or more guide members 408 can be used to improve stability and reduce unwanted movement of the drug cartridge 236 while it is coupled to the reusable drug delivery device 350. The guide member 408 can form part of the drug cartridge 236 or the drug delivery device housing 101. In one example, an exemplary method for using a recharge and drug storage hub is provided. The hub includes a port, a charging station, a drug storage chamber positioned in alignment within the port, and a drug In one example, an exemplary method for using a recharge and drug storage hub is provided. The hub includes a port, a charging station, a drug storage chamber positioned in alignment within the port, and a drug

[0061] In one example, an exemplary method for using a recharge and drug storage hub is provided. The hub includes a port, a charging station, a drug storage chamber positioned in alignment within the port, and a drug It is composed of a single-use drug cartridge for storing drugs arranged in a storage chamber. The user can recharge a rechargeable power source attached to a reusable drug delivery device by bringing at least a part of the reusable drug delivery device into contact with a charging station and arranging it. When the user is ready to administer the drug, the user removes the drug delivery device from the charging station and inserts at least a part of the drug delivery device through a port into a drug storage chamber to couple the drug cartridge to the charging station, remove the drug delivery device from the drug storage chamber and administer the drug. The hub may include a product identification system such as a Quick Response (QR) code arranged on the hub, for example, and the user can scan the code to receive information about the drug. Alternatively, the hub may also include a sensor (e.g., cartridge sensor 108) configured to scan the QR code and be able to. The hub may also issue commands or provide indicators to the user via at least one of an acoustic speaker arranged on the hub, one or more visual indicators arranged on the hub, and wireless transmission to a mobile device. The visual indicator may include any one of one or more LEDs, lights, light panels, and displays, or a combination thereof and be able to. A smartphone may be connected to the hub. In this case, the user can issue commands to instruct the hub to open, close, lock, or unlock the door of the port, or to instruct a temperature change device to keep the internal temperature of the storage chamber constant, and then instruct the hub to increase the temperature in the storage chamber to the controlled temperature. It can be.

[0062] ​​​In one embodiment, the method further comprises: The use may further include returning the drug to the drug storage chamber from which it was removed. The delivery device is inserted through the port into the drug storage chamber resulting in a drug cartridge. In some embodiments, the hub may be configured to detach the drug cartridge from the drug delivery device. The cartridge may be made up of a plurality of single-use drug cartridges, in which case the drug storage chamber may include a plurality of each of the drug storage chambers containing a plurality of disposable drug cartridges; The cartridge is configured to hold one of the single-use drug cartridges. In some embodiments, multiple drug storage chambers may be defined within the movable vial. In such an embodiment, the method further comprises the step of: After removal and / or use of the storage chamber, the bin may be moved to another one of the storage chambers. The method may further include aligning the storage chamber with the port.

[0063] FIG. 15 illustrates an exemplary protocol for using a recharging and medication storage hub with a mobile device. 1 is a flowchart depicting a process 1500. The process begins at step 1502. The hub system includes a drug delivery device (e.g., devices 150, 250, 350) and hubs (e.g., hubs 100, 200, 300). The hub includes a port, a charging station, a drug storage chamber, and a drug cartridge. The port may move between an open and a closed position or may have a locking and unlocking configuration. The charging station may have a door configured to switch between a drug When at least a part of the delivery device is placed in contact with the charging station, it is configured to charge (directly or inductively) a rechargeable power source on the drug delivery device. The drug storage chamber is designed to be aligned with the port. The drug cartridge is placed within the drug storage

[0064] In step 1504, process 1500 establishes a communication link between the hub and a mobile device (e.g., device 180). As discussed previously, the mobile device can be any of the following devices, namely, a smartphone, laptop, pocket bell, smartwatch, tablet, desktop, or any device that can receive a transmission and then send a response transmission but is not limited to these. The communication link can be wireless or wired and can be realized by any of the following communication protocols or technologies, namely, Bluetooth, RFID NFC, optical fiber communication, universal serial bus (USB) communication, Wi-Fi, etc. wireless network, cellular network, or infrared (IR), but is not limited to these.

[0065] In step 1506, when the communication link is established, the mobile device can send instructions to the hub to prepare the drug for administration. The instructions can be issued from the mobile device based on user input on the mobile device and / or based on a pre-programmed schedule for drug administration.

[0066] In step 1508, in response to receiving instructions to prepare the drug for administration, the hub then opens or unlocks the door to the port to allow access to the drug cartridge​​ may enable access. The hub may issue to the user one or more indicators that the preparation for drug administration is ready, but this is not essential. The indicators may be issued via any one or a combination of one or more audible sounds generated by at least one acoustic speaker disposed on the hub, one or more visual indicators, and wireless transmission to the mobile device. The visual indicators may further include any one or any combination of one or more LEDs, light rings, light panels, and / or displays. These indicators may be issued before or after the port is unlocked or opened in step 1508.

[0067] Next, in step 1510, the user may remove the drug delivery device from the charging station. When removed from the charging station, in step 1512, the user may insert the drug delivery device into the port to couple the drug delivery device with the drug cartridge. After coupling the drug delivery device with the drug cartridge, in step 1514, the user may then remove the drug delivery device so as to remove the drug cartridge from the drug storage chamber. When removed from the port, the user may activate the drug delivery device to administer the drug. Process 1500 may further include discarding the drug cartridge by removing the used drug cartridge from the drug delivery device and placing the used cartridge in the drug storage chamber. For example, the user may move the release lever 400 (depicted in FIGS. 12-13) in the proximal direction to decouple the drug cartridge from the drug delivery device.

[0068] ​​​​​​​​​​​​​​​​​ In some embodiments, the hub may further comprise a temperature changing device configured to control the internal temperature of the drug storage chamber. The temperature changing device may, for example, adjust the internal temperature of the drug storage chamber by cooling the internal temperature of the drug storage chamber to a storage temperature (e.g., 30-34 degrees Fahrenheit). In such embodiments, in response to an instruction (step 1506) to prepare the drug for administration, the hub may use the temperature changing device to raise the internal temperature of the drug storage chamber to an administration temperature (e.g., room temperature). Optionally, when the internal temperature of the storage chamber reaches the administration temperature, the hub may issue one or more indicators using the aforementioned indicator method, for example, using the speaker 222 or the user interface 106, to inform the user that the drug cartridge is ready for administration. The terms "first," "second," "third," etc., whether used in this specification or in the claims, are provided to distinguish similar elements and are not necessarily for describing an order or a chronological sequence. Such terms may be interchangeable in a suitable environment (unless specifically disclosed otherwise), and it should be understood that the embodiments of the disclosure described herein may operate in other orders and / or configurations than those described or illustrated herein. Although the present invention has been described as having an exemplary design, the present invention can be further modified within the spirit and scope of the present disclosure. Therefore, this application is intended to cover any variations, uses, or adaptations of the present invention using the general principles of the present invention. Furthermore, this application is intended to cover such departures from the present disclosure as come within known or customary practice in the art to which this invention pertains. The description is thus to be regarded as illustrative rather than restrictive, and all such modifications as would be obvious to one skilled in the art are intended to be included within the scope of this invention. Any reference to an element herein using the articles "a," "an," or "the" is not to be construed as limiting the element to a single instance, but rather should be read as encompassing one or more of such elements, unless the context clearly dictates otherwise.

[0069] The use of the terms "including," "comprising," or "having" and variations thereof herein is meant to encompass the elements listed thereafter and equivalents thereof as well as additional elements. The terms "connected" and "coupled" and variations thereof herein are used in their broadest sense and include both direct and indirect connections and couplings. In the case of indirect connections or couplings, the intervening elements are included within the scope of the claims. The terms "axial" and "axially" and variations thereof herein refer to directions along the central axis of an object. The terms "radial" and "radially" and variations thereof herein refer to directions extending from the central axis of an object. The terms "circumferential" and "circumferentially" and variations thereof herein refer to directions around the circumference of an object.

[0070] The present invention has been described as having an exemplary design, and the present invention can be further modified within the spirit and scope of the present disclosure. Therefore, this application is intended to cover any variations, uses, or adaptations of the present invention using the general principles of the present invention. Furthermore, this application is intended to cover such departures from the present disclosure as come within known or customary practice in the art to which this invention pertains. , within the known or customary practice in the technical field related to the present invention, anything that departs from this disclosure is intended to be encompassed.

[0071] Various aspects including but not limited to the following aspects are described in this disclosure.

[0072] 1. A recharge and drug storage hub for a drug delivery device, comprising a housing defining a port sized to receive at least a portion of the drug delivery device, a charging station disposed in the housing configured to charge a rechargeable power source attached to the drug delivery device when at least a portion of the drug delivery device is positioned proximate to a charging station, and a drug storage chamber configured to be positionally aligned with the port, the drug storage chamber being configured to store a drug cartridge, wherein at least a portion of the drug delivery device is inserted into the drug storage chamber through the port and then withdrawn from the drug storage chamber, and the drug storage chamber is configured such that the drug delivery device can withdraw the drug cartridge from the drug storage chamber. The recharge and drug storage hub.

[0073] 2. The hub according to aspect 1, wherein the drug cartridge comprises a barrel for holding a drug, a needle, and a movable plunger, and comprises a syringe.

[0074] 3. The hub according to aspect 1 or 2, further comprising a drug cartridge, wherein the drug cartridge stores a drug.

[0075] 4. The drug delivery device comprises a proximal end and a distal end, and the port is at least ​​​​​​​The hub according to any one of Aspects 1 to 3, configured to receive the proximal end.

[0076] 5. Further comprising a cooling device configured to lower the internal temperature of the drug storage chamber, the hub according to any one of Aspects 1 to 4. The hub according to any one of Aspects 1 to 4, further comprising a heating device configured to raise the internal temperature of the drug storage chamber.

[0077] 6. Further comprising a heating device configured to raise the internal temperature of the drug storage chamber, the hub according to any one of Aspects 1 to 4. The hub according to any one of Aspects 1 to 4, further comprising a heating device configured to raise the internal temperature of the drug storage chamber.

[0078] 7. Further comprising a temperature changing device configured to both lower and raise the internal temperature of the drug storage chamber, the hub according to any one of Aspects 1 to 4. The hub according to any one of Aspects 1 to 4, further comprising a temperature changing device configured to both lower and raise the internal temperature of the drug storage chamber.

[0079] 8. The drug cartridge is the first drug cartridge among a plurality of drug cartridges, and the drug storage chamber is the first drug storage chamber among a plurality of drug storage chambers defined in a bin at least partially disposed within the housing, and each drug storage chamber of the plurality of drug storage chambers is configured to store one drug cartridge among the plurality of drug cartridges. The hub according to any one of Aspects 1 to 7. The drug cartridge is the first drug cartridge among a plurality of drug cartridges, and the drug storage chamber is the first drug storage chamber among a plurality of drug storage chambers defined in a bin at least partially disposed within the housing, and each drug storage chamber of the plurality of drug storage chambers is configured to store one drug cartridge among the plurality of drug cartridges. The hub according to any one of Aspects 1 to 7. The drug cartridge is the first drug cartridge among a plurality of drug cartridges, and the drug storage chamber is the first drug storage chamber among a plurality of drug storage chambers defined in a bin at least partially disposed within the housing, and each drug storage chamber of the plurality of drug storage chambers is configured to store one drug cartridge among the plurality of drug cartridges. The hub according to any one of Aspects 1 to 7. The drug cartridge is the first drug cartridge among a plurality of drug cartridges, and the drug storage chamber is the first drug storage chamber among a plurality of drug storage chambers defined in a bin at least partially disposed within the housing, and each drug storage chamber of the plurality of drug storage chambers is configured to store one drug cartridge among the plurality of drug cartridges. The hub according to any one of Aspects 1 to 7. The hub according to any one of Aspects 1 to 7, wherein the drug cartridge is the first drug cartridge among a plurality of drug cartridges, the drug storage chamber is the first drug storage chamber among a plurality of drug storage chambers defined in a bin at least partially disposed within the housing, and each drug storage chamber of the plurality of drug storage chambers is configured to store one drug cartridge among the plurality of drug cartridges.

[0080] 9. The hub according to Aspect 8, wherein the bin is movable to align only one of the plurality of drug storage chambers with the port at a time. The hub according to Aspect 8, wherein the bin is movable to align only one of the plurality of drug storage chambers with the port at a time.

[0081] 10. The hub according to Aspect 9, wherein the bin is configured to rotate to align only one of the plurality of drug storage chambers with the port at a time. The hub according to Aspect 9, wherein the bin is configured to rotate to align only one of the plurality of drug storage chambers with the port at a time.

[0082] 11. The port is the first port among a plurality of ports defined within the housing. , each port is sized to receive at least a portion of the drug delivery device, The drug cartridge is the first drug cartridge among a plurality of drug cartridges, The drug storage chamber is the first drug storage chamber among a plurality of drug storage chambers, Each drug storage chamber is arranged in position alignment with a separate port of the plurality of ports, Each drug storage chamber is configured to store one of the plurality of drug cartridges The hub according to any one of Aspects 1 to 7.

[0083] 12. The drug storage chamber is configured to store the drug cartridge after the drug cartridge has been used and decoupled from the drug delivery device, The hub according to any one of Aspects 1 to 11.

[0084] 13. The hub further comprises a communication device and a controller configured to receive data recorded by a sensor attached to the drug delivery device via the communication device and transmit information based on the recorded data to a remote server via the communication device, The hub according to any one of Aspects 1 to 12.

[0085] 14. The hub further comprises one or more sensors configured to record data indicating the status of the hub, a communication device, and a controller configured to transmit data based on the recorded data to a remote server via the communication device, The hub according to any one of Aspects 1 to 12.

[0086] 15. A system for delivering and storing drugs, the system comprising the rechargeable and drug storage hub according to any one of Aspects 1 to 14 and a drug delivery device. ​​​​​​

[0087] 16. The drug delivery device is configured to releasably couple to a drug cartridge. The system according to aspect 15, comprising a coupling mechanism.

[0088] 17. The system according to aspect 16, wherein the coupling mechanism is a magnetic coupling mechanism.

[0089] 18. The coupling mechanism on the drug delivery device comprises a first magnet and a release sleeve, and the drug cartridge comprises a second magnet configured to couple with the first magnet. The system according to aspect 17. The system according to aspect 18.

[0090] 19. The coupling mechanism is configured to enable a user to decouple the drug cartridge from the drug delivery device by moving the release sleeve. The system according to aspect 17 or 18. The system according to aspect 19.

[0091] 20. The release sleeve comprises a hollow cylindrical body and one or more tabs extending into the internal volume of the cylindrical body. When the user moves the release sleeve in the proximal direction, the one or more tabs exert a proximal force that overcomes the magnetic force between the first magnet and the second magnet on the distal end of the drug cartridge. The system according to aspect 19. The system according to aspect 20.

[0092] 21. A method of using a drug delivery device and a recharge and drug storage hub for the drug delivery device, the hub having a port, a charging station, a drug storage chamber aligned with the port, and a drug cartridge disposed in the drug storage chamber for storing a drug. The method comprises disposing at least a portion of the drug delivery device in proximity to the charging station to charge a rechargeable power source attached to the drug delivery device, and delivering drug from the drug cartridge to the drug delivery device from the drug storage chamber through the port. ​​​​​​​​ removing the delivery device and inserting at least a portion of the drug delivery device through a port into a drug storage chamber to couple the drug delivery device with a drug cartridge stored in the drug storage chamber; and removing the drug delivery device, once coupled with the drug cartridge, from the port, wherein the method comprises: a method. 22. The method according to aspect 21, wherein a Quick Response (QR) code is disposed on the hub and the QR code contains information about the drug.

[0093] 23. The method according to aspect 21 or 22, wherein the hub provides an indication to the user that the drug cartridge is ready for use via at least one of an acoustic speaker disposed on the hub, one or more visual indicators disposed on the hub, and wireless transmission to a mobile device.

[0094] 24. The method according to any one of aspects 21 to 23, wherein the port is covered by a door and the hub is controlled via a smartphone such that the user can instruct the hub to open, close, lock, or unlock the door. 25. The method according to any one of aspects 21 to 23, wherein the hub is controlled via a smartphone and the hub further comprises a temperature changing device configured to cool the internal temperature of the drug storage chamber to a storage temperature, and the method further comprises instructing the hub via the smartphone to increase the internal temperature of the drug storage chamber using the temperature changing device.

[0095]

[0096]

[0097] ​​​​​​​​​​​26. After activating the drug delivery device to administer the drug, at least one part of the drug delivery device is reinserted into the drug storage chamber through the port, and the drug cartridge coupled to the drug delivery device is released into the drug storage chamber for disposal. The method according to any one of aspects 21 to 25. 27. The drug cartridge is the first drug cartridge among a plurality of drug cartridges, the drug storage chamber is the first drug storage chamber among a plurality of drug storage chambers defined in a bin disposed within the hub, and each drug storage chamber of the plurality of drug storage chambers is configured to store one of the plurality of drug cartridges. The method further includes removing the drug delivery device once coupled to the first drug cartridge from the port to remove the first drug cartridge from the first drug storage chamber, and moving the bin to align another drug storage chamber among the plurality of drug storage chambers with the port. The method according to any one of aspects 21 to 26. 28. A method of using a rechargeable and drug storage hub system in cooperation with a mobile device, the method including providing a hub system having a drug delivery device with a rechargeable power source and a hub, the hub being configured to perform at least one of (i) moving between an open position and a closed position and (ii) switching between a locked configuration and an unlocked configuration, and a door, and a charging station configured to charge the rechargeable power source of the drug delivery device when at least a part of the drug delivery device is disposed in close contact with the charging station. 29. The method according to aspect 28, further including providing a mobile device having a display and a user interface, the mobile device being configured to communicate with the hub system, and the hub system being configured to transmit information to the mobile device, and the mobile device being configured to receive the information and display the information on the display.

[0098] 30. The method according to aspect 28 or 29, further including providing a mobile device having a processor and a memory, the mobile device being configured to communicate with the hub system, and the hub system being configured to transmit data to the mobile device, and the mobile device being configured to receive the data and store the data in the memory. 31. The method according to any one of aspects 28 to 30, further including providing a mobile device having a communication module, the mobile device being configured to communicate with the hub system, and the hub system being configured to receive data from the mobile device, and the mobile device being configured to transmit the data to the hub system. 32. The method according to any one of aspects 28 to 31, further including providing a mobile device having a battery, the mobile device being configured to communicate with the hub system, and the hub system being configured to charge the battery of the mobile device when the mobile device is disposed in close contact with the hub system. 33. The method according to any one of aspects 28 to 32, further including providing a mobile device having a sensor, the mobile device being configured to communicate with the hub system, and the hub system being configured to receive data from the sensor of the mobile device, and the mobile device being configured to transmit the data to the hub system. 34. The method according to any one of aspects 28 to 33, further including providing a mobile device having a camera, the mobile device being configured to communicate with the hub system, and the hub system being configured to receive images captured by the camera of the mobile device, and the mobile device being configured to transmit the images to the hub system. 35. The method according to any one of aspects 28 to 34, further including providing a mobile device having a microphone, the mobile device being configured to communicate with the hub system, and the hub system being configured to receive audio data captured by the microphone of the mobile device, and the mobile device being configured to transmit the audio data to the hub system. 36. The method according to any one of aspects 28 to 35, further including providing a mobile device having a speaker, the mobile device being configured to communicate with the hub system, and the hub system being configured to transmit audio data to the speaker of the mobile device, and the mobile device being configured to receive the audio data and play the audio data through the speaker. 37. The method according to any one of aspects 28 to 36, further including providing a mobile device having a touch screen, the mobile device being configured to communicate with the hub system, and the hub system being configured to transmit touch screen event data to the mobile device, and the mobile device being configured to receive the touch screen event data and process the touch screen event data.

[0099] 38. The method according to any one of aspects 28 to 37, further including providing a mobile device having an application, the mobile device being configured to communicate with the hub system, and the hub system being configured to transmit application data to the mobile device, and the mobile device being configured to receive the application data and run the application using the application data. 39. The method according to any one of aspects 28 to 38, further including providing a mobile device having a security module, the mobile device being configured to communicate with the hub system, and the hub system being configured to transmit security data to the mobile device, and the mobile device being configured to receive the security data and use the security data to authenticate the mobile device with the hub system. 40. The method according to any one of aspects 28 to 39, further including providing a mobile device having a location module, the mobile device being configured to communicate with the hub system, and the hub system being configured to receive location data from the location module of the mobile device, and the mobile device being configured to transmit the location data to the hub system. 41. The method according to any one of aspects 28 to 40, further including providing a mobile device having a notification module, the mobile device being configured to communicate with the hub system, and the hub system being configured to transmit notification data to the mobile device, and the mobile device being configured to receive the notification data and display the notification data on the display. 42. The method according to any one of aspects 28 to 41, further including providing a mobile device having a settings module, the mobile device being configured to communicate with the hub system, and the hub system being configured to receive settings data from the settings module of the mobile device, and the mobile device being configured to transmit the settings data to the hub system. 43. The method according to any one of aspects 28 to 42, further including providing a mobile device having a software update module, the mobile device being configured to communicate with the hub system, and the hub system being configured to receive software update data from the software update module of the mobile device, and the mobile device being configured to transmit the software update data to the hub system. An electrical station, a drug storage chamber, and a drug cartridge disposed within the drug storage chamber for storing drugs, and a hub system comprising the same; establishing a communication link between the hub and the mobile device; and sending a command from the mobile device to the hub to prepare the drug cartridge for administration, the command causing the hub to move the door to the open position or switch the door to the unlocked configuration to enable access to the drug cartridge; removing the drug delivery device from the charging station; inserting the drug delivery device into the port to couple the drug delivery device to the drug cartridge; removing the drug cartridge from the drug storage chamber; and in response to the drug cartridge being coupled to the drug delivery device, removing the drug delivery device from the port. A method, further comprising removing the drug cartridge from the drug delivery device by inserting the drug delivery device into the port and decoupling the drug cartridge from the drug delivery device, and placing the drug cartridge in the drug storage chamber to discard the drug cartridge. The method according to aspect 28, further comprising using a temperature change device to cool the internal temperature of the drug storage chamber to the storage temperature; raising the internal temperature of the drug storage chamber to the administration temperature using the temperature change device in response to receiving the command; and providing an indicator to the user only after the internal temperature of the drug storage chamber reaches the administration temperature. The method according to aspect 28 or 29, wherein the hub further comprises a temperature change device configured to control the internal temperature of the drug storage chamber.

[0100]

[0101]

[0102] ​​​​​​​​​​​​​​​31. The indicator can be issued via at least one of one or more audible sounds generated from at least one acoustic speaker disposed on the hub, one or more visual indicators disposed on the hub, and one or more wireless transmissions from the hub to the mobile device, according to any of aspects 28 to 30. ​

Claims

1. 1. A recharging and medication storage hub for a drug delivery device, comprising: defining a port sized to receive at least a portion of the drug delivery device; Housing and a charging station disposed on the housing, the charging station being adapted to charge at least one of the When a portion is positioned adjacent to the charging station, a charging station configured to charge an attached rechargeable power source; a drug storage chamber configured to align with the port; a drug storage chamber, the storage chamber configured to store a drug cartridge; , At least a portion of the drug delivery device is inserted into the drug storage chamber through the port. and then, when withdrawn from the drug storage chamber, the drug delivery device delivers the drug. The drug storage chamber is adapted to allow the drug cartridge to be withdrawn from the storage chamber. A recharging and drug storage hub comprising a storage chamber.

2. The drug cartridge includes a barrel for holding a drug, a needle, and a movable plunger. The hub of claim 1 comprising a syringe.

3. The method further comprises the steps of:

3. The hub according to claim 1 or 2.

4. the drug delivery device comprising a proximal end and a distal end; The port is configured to receive at least the proximal end of the drug delivery device. A hub according to any one of claims 1 to 3.

5. a cooling device configured to reduce an internal temperature of the drug storage chamber. A hub according to any one of claims 1 to 4.

6. a heating device configured to increase an internal temperature of the medicament storage chamber. A hub according to any one of claims 1 to 4.

7. The internal temperature of the drug storage chamber is both decreased and increased. The hub according to any one of claims 1 to 4, further comprising a temperature changing device configured in 。

8. The drug cartridge is a first drug cartridge of a plurality of drug cartridges. can be, The drug storage chamber is defined within a vial that is at least partially disposed within the housing. a first medicament storage chamber of a plurality of medicament storage chambers, Each of the plurality of drug storage chambers is provided with a drug cartridge.

8. The drug cartridge according to claim 1, wherein the drug cartridge is adapted to store one of the drug cartridges. The hub of claim 1.

9. The vial aligns only one of the plurality of drug storage chambers with the port at a time. The hub of claim 8 , wherein the hub is movable into alignment.

10. The vial aligns only one of the plurality of drug storage chambers with the port at a time. The hub of claim 9 configured to rotate into alignment.

11. the port is a first port of a plurality of ports defined in the housing; and each port is sized to receive at least a portion of the drug delivery device. And, The drug cartridge is a first drug cartridge of a plurality of drug cartridges. the law of nature, the drug storage chamber is a first drug storage chamber of a plurality of drug storage chambers; and each drug storage chamber is disposed in alignment with a separate port of the plurality of ports. each drug storage chamber is provided with a drug cartridge of the plurality of drug cartridges; A hub according to any one of claims 1 to 7, configured to store ridges.

12. The drug storage chamber is adapted to receive the drug cartridge and to receive the drug from the drug delivery device. The device is configured to store the drug cartridge after being uncoupled.

1. A hub as described in any one of claims 1 to 5.

13. The hub is A communication device; A controller, Via the communication device, the drug delivery device receives a signal recorded by a sensor attached to the drug delivery device. Receive the data to be Transmitting information based on the recorded data to a remote server via the communication device. and a controller configured to:

2. The hub described in paragraph 1.

14. The hub is one or more sensors configured to record data indicative of a status of the hub; 、 A communication device; Transmitting data based on the recorded data to a remote server via the communication device. and a controller configured to: The hub described in.

15. A system for delivering and storing a drug, comprising: The system includes an on-board recharging and drug storage hub and a drug delivery device.

16. The drug delivery device is configured to releasably couple with a drug cartridge. The system of claim 15 further comprising a docking mechanism.

17. The system of claim 16 , wherein the coupling mechanism is a magnetic coupling mechanism.

18. The coupling mechanism on the drug delivery device comprises a first magnet and a release sleeve, the cartridge comprises a second magnet configured to mate with the first magnet; 20. The system of claim 17.

19. The coupling mechanism allows a user to release the medication cartridge by moving the release sleeve.

5. The method of claim 1, further comprising:

19. The system according to claim 17 or 18.

20. The release sleeve has a hollow cylindrical body and a recess extending into an interior volume of the cylindrical body. and wherein when the user moves the release sleeve proximally, the one The tabs provide a proximal force that overcomes the magnetic force between the first magnet and the second magnet. The system of claim 19 , wherein the system is applied to a distal end of the drug cartridge.

21. Drug delivery device and method of using a recharging and drug storage hub for said drug delivery device - Patents.com the hub includes a port, a charging station, and a drug storage device aligned with the port. a drug storage chamber, and a drug cartridge for storing a drug disposed within the drug storage chamber. and wherein the method comprises: A small amount of the drug delivery device is provided for charging a rechargeable power source attached to the drug delivery device. and disposing at least a portion of the vehicle adjacent to the charging station. removing the medication delivery device from the charging station; At least a portion of the drug delivery device is inserted into the drug storage chamber through the port. and inserting the drug delivery device into the drug cart stored in the drug storage chamber. joining with the ridge; To remove the drug cartridge from the drug storage chamber, and removing the drug delivery device from the port once coupled to the device.

22. A Quick Response (QR) code is placed on the hub, and the QR code (registration 22. The method of claim 21, wherein a trademark (such as a brand name, product code, product ...

23. The hub may include an audio speaker disposed on the hub, one or more via at least one of a visual indicator of the device and a wireless transmission to the mobile device; providing an indication to a user that the medication cartridge is ready for use.

23. The method according to claim 21 or 22.

24. The port is covered by a door, and the user can control the hub to open, close, lock, or The hub is controlled via a smartphone so that unlocking can be commanded.

24. The method according to any one of claims 21 to 23.

25. The hub is controlled via a smartphone, and the hub controls the drug storage chamber. The method further comprises a temperature changing device configured to cool the internal temperature to a storage temperature. The method includes using the temperature altering device to increase the internal temperature of the drug storage chamber. The method according to any one of claims 21 to 20, further comprising instructing the hub via the smartphone to:

4. The method according to any one of claims 3 to 4.

26. After activating the drug delivery device to administer the drug, reinserting at least a portion of the drug storage chamber through the port; and The drug cartridge coupled with the drug delivery device is inserted into the drug storage chamber for disposal. The method of any one of claims 21 to 25, further comprising: releasing the

27. The drug cartridge is a first drug cartridge of a plurality of drug cartridges. the drug storage chamber comprising a plurality of drug reservoirs defined within vials disposed within the hub; a first drug storage chamber of the storage chambers, A drug storage chamber stores one of the drug cartridges. and configured to store the information, the method comprising: to remove the first drug cartridge from the first drug storage chamber. removing the drug delivery device once coupled with the drug cartridge from the port; and connecting the vial to another one of the plurality of drug storage chambers. and moving the sensor into alignment with the sensor. The method described.

28. 1. A method of using a recharging and medication storage hub system in conjunction with a mobile device, comprising: providing the hub system, the hub system comprising: a drug delivery device having a rechargeable power source; a hub, the hub comprising: (i) moving between open and closed positions; and (ii) locked and unlocked configurations. and switching between The port to At least a portion of the drug delivery device is disposed proximate to the charging station. a charging station configured to charge the rechargeable power source of the drug delivery device when the And, a drug storage chamber; a drug cartridge for storing a drug disposed within the drug storage chamber; providing a hub system comprising: establishing a communications link between the hub and the mobile device; receiving instructions from the mobile device to prepare the medication cartridge for administration; a hub, the command instructing the hub to move the door to the open position; or switching the door to the unlocked configuration to allow access to the drug cartridge. Enabling access, transmitting, removing the medication delivery device from the charging station; Insert the drug delivery device into the port to connect the drug delivery device to the drug cartridge. Combining and To remove the drug cartridge from the drug storage chamber, and removing the drug delivery device from the port once coupled to the device.

29. Inserting the drug delivery device into the port and dispensing the drug cartridge into the drug delivery device. and placing the drug cartridge in the drug storage chamber.

30. The method of claim 28, further comprising discarding the medication cartridge.

30. The hub includes a temperature changer configured to control an internal temperature of the drug storage chamber. The method further comprises: Cooling the internal temperature of the drug storage chamber to a storage temperature using the temperature altering device. And, In response to receiving the command, the temperature change device is used to change the temperature of the interior of the drug storage chamber. raising the temperature of the part to a dosing temperature; providing an indication to a user only after the internal temperature of the medication storage chamber has reached the administration temperature; 30. The method of claim 28 or 29, further comprising:

31. The indicator is generated from at least one audio speaker disposed on the hub. one or more audible tones, one or more visual indicators disposed on the hub, and one or more via at least one of one or more wireless transmissions from the The method according to any one of claims 28 to 30,

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