Tablet-form skin cleanser

Abstract

To provide a tablet-form skin cleanser having superior moldability, disintegrability, and usability.SOLUTION: A tablet-form skin cleanser comprises: (A) crystalline cellulose; (B) an anionic surfactant; and (C) corn starch.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a tablet-shaped (tablet) skin cleanser.

Background Art

[0002] A tablet-shaped skin cleanser (hereinafter also referred to as a tablet-shaped cleanser) formed by compressing powder is known. It is required that the tablet-shaped cleanser quickly disintegrates when it comes into contact with water and is excellent in usability such as quick foaming property and foam amount. In order to improve the disintegration property of the tablet-shaped cleanser, for example, Patent Documents 1 and 2 propose blending a carbonate and an acid as foaming components, Patent Document 3 proposes having a macro void ratio of 15% or more and increasing the voids, and Patent Document 4 proposes blending croscarmellose sodium as a disintegrant. However, all of the tablet-shaped cleansers described in Patent Documents 1 to 4 require about one minute for disintegration, and further improvement in disintegration property has been demanded.

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Patent Document 2

Patent Document 3

Patent Document 4

Summary of the Invention

Problems to be Solved by the Invention

[0004] An object of the present invention is to provide a tablet-shaped skin cleanser excellent in moldability, disintegration property, and usability.

Means for Solving the Problems

[0005] Means for solving the problems of the present invention are as follows. 1. A tablet-shaped skin cleanser containing (A) crystalline cellulose, (B) an anionic surfactant, and (C) corn starch. 2. The tablet-shaped skin cleanser according to 1, wherein the mass ratio of component (A) to component (C) (total is 100) is 40 to 80:60 to 20.

Effects of the Invention

[0006] The tablet-shaped skin cleanser of the present invention is excellent in moldability and disintegratability, and is also excellent in usability such as foaming speed, foam amount, foam quality, and foam persistence. Since the skin cleanser of the present invention is in tablet form and does not contain water, it can be made preservative-free. Since the skin cleanser of the present invention is in tablet form, it is easy to carry and store. The skin cleanser of the present invention uses less water in the manufacturing process and is promising from the viewpoint of water resource protection.

Modes for Carrying Out the Invention

[0007] The tablet-shaped skin cleanser of the present invention contains (A) crystalline cellulose, (B) an anionic surfactant, and (C) corn starch. By containing these components (A), (B), and (C), the tablet-shaped skin cleanser of the present invention is excellent in moldability, disintegratability, and usability.

[0008] (A) Crystalline cellulose Crystalline cellulose can be obtained, for example, by drying a cellulose dispersion obtained by dispersing a hydrolyzed natural cellulose-based substance in an appropriate medium. The raw material of crystalline cellulose is not particularly limited, and wood fiber, non-wood fiber, bacterial cellulose, etc. can be used. As the crystalline cellulose, those used as pharmaceutical additives or food additives can be used without particular limitation, and commercially available products such as "Ceolus" sold by Asahi Kasei Corporation and microcrystalline cellulose "MCC" sold by DuPont Corporation can also be used. Crystalline cellulose can be used alone or in combination of two or more kinds with different degrees of polymerization, particle diameters, bulk densities, etc.

[0009] The content of component (A) in the tablet-shaped skin cleanser of the present invention is not particularly limited, but is preferably 5% by mass or more and 50% by mass or less based on the whole. If the content of this component (A) is less than 5% by mass, molding may be difficult, and if it exceeds 50% by mass, the disintegrability and usability may decrease. The content of component (A) based on the whole is more preferably 15% by mass or more, further preferably 20% by mass or more, still more preferably 25% by mass or more, and more preferably 45% by mass or less, and further preferably 40% by mass or less.

[0010] (B) Anionic surfactant Examples of the anionic surfactant include higher fatty acid salts, N-acylglycine salts, N-acylglutamic acid salts, N-acylalanine salts, N-acylisethionic acid salts, N-acylmethyltaurine salts, monoalkyl phosphates, ether carboxylates, alkyl sulfonates, sulfosuccinates, and the like. Examples of the acyl group in the above-mentioned N-acyl-based anionic surfactant include octanoyl group, decanoyl group, lauroyl group, myristoyl group, palmitoyl group, stearoyl group, oleoyl group, linoleoyl group, etc. The acyl group may be derived from a mixed fatty acid, and specific examples include coconut oil fatty acid acyl group (cocoyl group), palm oil fatty acid acyl group, palm kernel oil fatty acid acyl group, beef tallow fatty acid acyl group, etc. Examples of the salt include alkali metal salts such as sodium and potassium, alkanolamine salts such as triethanolamine, and basic amino acid salts such as lysine and arginine. The anionic surfactant can be used alone or in combination of two or more different kinds.

[0011] The content rate of component (B) in the tablet-shaped skin cleanser of the present invention is not particularly limited, but is preferably 10% by mass or more and 40% by mass or less based on the whole. If the content rate of this component (B) is less than 10% by mass, the detergency may be insufficient, and if it exceeds 40% by mass, the disintegrability may decrease. The content rate of component (B) based on the whole is more preferably 15% by mass or more, further preferably 35% by mass or less, and still further preferably 30% by mass or less.

[0012] ·Other surfactants In addition to the (B) anionic surfactant, the tablet-shaped skin cleanser of the present invention can be blended with other surfactants such as amphoteric surfactants, cationic surfactants, and nonionic surfactants. When the tablet-shaped skin cleanser of the present invention contains other surfactants, it is preferable to contain 50% by mass or more of the (B) anionic surfactant based on all the surfactants. If the amount of the (B) anionic surfactant is less than 50% by mass, the usability may decrease. The ratio of the (B) anionic surfactant to all the surfactants is more preferably 60% by mass or more, further preferably 70% by mass or more, still further preferably 80% by mass or more, even further preferably 90% by mass or more, and even further preferably 95% by mass or more.

[0013] (C) Corn starch Corn starch is starch derived from corn. Although the mechanism is unknown, by using components (A), (B), and (C) in combination, a tablet-shaped skin cleanser excellent in disintegrability and usability can be obtained. When starches other than (C) corn starch are used, the moldability is inferior, or even if it can be tableted, the disintegrability and usability are inferior. As the corn starch, those used as pharmaceutical additives or food additives can be used without particular limitation, but an unmodified product is preferable. The content rate of component (C) in the tablet-shaped skin cleanser of the present invention is not particularly limited, but it is preferably 5% by mass or more and 50% by mass or less based on the whole. If the content rate of this component (C) is less than 5% by mass, the disintegrability may decrease, and if it exceeds 50% by mass, the moldability may decrease. The content rate of component (C) based on the whole is more preferably 10% by mass or more, still more preferably 15% by mass or more, even more preferably 20% by mass or more, and also more preferably 40% by mass or less, still more preferably 35% by mass or less.

[0014] ·Other starches The tablet-shaped skin cleanser of the present invention can contain, in addition to (C) corn starch, other starches such as potato starch, tapioca starch, rice starch, wheat starch, and modified starches thereof. However, when the tablet-shaped skin cleanser of the present invention contains other starches, it is preferable to contain 50% by mass or more of (C) corn starch based on all starches. If the proportion of (C) corn starch is less than 50% by mass, the moldability may decrease. The proportion of (C) corn starch based on all starches is more preferably 60% by mass or more, still more preferably 70% by mass or more, even more preferably 80% by mass or more, even more preferably 90% by mass or more, and even more preferably 95% by mass or more.

[0015] The tablet-shaped skin cleanser of the present invention preferably has a mass ratio of component (A) to component (C) (A:C, total is 100) of 40 - 80:60 - 20 from the viewpoint of the balance between moldability and disintegrability. This ratio is more preferably 45 - 70:55 - 30, and still more preferably 50 - 70:50 - 30.

[0016] ·Other compounding components In the tablet-shaped skin cleanser of the present invention, polyhydric alcohols, saccharides, sugar alcohols, preservatives, sequestering agents, medicinal components, extenders (excipients), disintegrants, lubricants, fragrances, etc. can be contained within a range that does not impair the effects of the present invention.

[0017] Examples of polyhydric alcohols, saccharides, and sugar alcohols include glycerin, diglycerin, 1,3-butylene glycol (BG), propylene glycol, dipropylene glycol, 1,2-pentanediol, sorbitol, mannose, mannitol, galactose, galactitol, maltose, trehalose, erythrulose, erythritol, xylose, xylitol, sucrose, lactose, lactitol, difructose anhydride, and the like.

[0018] Examples of preservatives include methyl paraben, ethyl paraben, and the like. However, since the tablet-shaped skin cleanser of the present invention does not contain water and bacteria are less likely to grow, the blending amount of the preservative is preferably 0.5% by mass or less, more preferably 0.1% by mass or less, and most preferably not contained, based on the whole. Examples of sequestering agents include edetate salts such as disodium ethylenediaminetetraacetate, edetic acid, and sodium edetate. Examples of medicinal ingredients include vitamin C such as L-ascorbic acid, L-ascorbic acid phosphate ester, L-ascorbic acid monopalmitate, L-ascorbic acid dipalmitate, L-ascorbic acid-2-glucoside; whitening agents such as glutathione and extract of Saxifraga stolonifera; skin activators such as royal jelly and extract of Fagus crenata; blood circulation promoters such as capsaicin, zingerone, cantharidin, caffeine, tannic acid, and γ-oryzanol; anti-inflammatory agents such as glycyrrhetic acid derivatives and azulene; and enzymes such as protease and lysozyme chloride.

[0019] Examples of bulking agents (excipients) include lactose, magnesium aluminometasilicate, calcium silicate, talc, kaolin, silica, mica, zeolite, bentonite, titanium dioxide, dextrin, and the like. However, the content rate of the bulking agents other than (A), (C), and other starches with respect to the whole tablet-shaped skin cleanser is preferably 10% by mass or less, more preferably 5% by mass or less, still more preferably 3% by mass or less, and even more preferably 1% by mass or less. Examples of disintegrants include crosscarmellose, hydroxypropylcellulose, hydroxypropylmethylcellulose, polyvinyl alcohol, polyacrylic acid, sodium polyacrylate, polymethacrylic acid, gum arabic, gelatin, agar, pullulan, crosslinked polyvinylpyrrolidone, and the like. Examples of lubricants include calcium stearate, magnesium stearate, sucrose esters, and the like.

[0020] The tablet-shaped skin cleanser of the present invention can be tabletted by a known method to form tablets.

Examples

[0021] In Examples 1 to 17 and Comparative Examples 1 to 13, each component was blended at the mass ratios shown in Tables 1 to 3 and tabletted at a pressure of 700 kg to prepare tablet-shaped skin cleansers (about 700 mg). Each component used is as follows. (A) Crystalline cellulose Crystalline cellulose [50 μm, 0.21 g / cm 3 (manufactured by Asahi Kasei Corporation, Ceolus ST-02) Crystalline cellulose [50 μm, 0.12 g / cm 3 (manufactured by Asahi Kasei Corporation, Ceolus ST-100) Crystalline cellulose [20 μm, 0.17 g / cm 3 (manufactured by Asahi Kasei Corporation, Ceolus OD-20F) Crystalline cellulose [90 μm, 0.29 g / cm 3 (manufactured by Asahi Kasei Corporation, Ceolus UF-F702) The numerical values in [ ] represent the average particle size (μm) and bulk density (g / cm 3 ).

[0022] (B) Anionic surfactant Sodium coco isethionate (Innospec Performance Chemicals, Pureact I-78) Sodium lauroyl aspartate (manufactured by Asahi Kasei Fine Chemicals Corporation, Aminophermer FLMS-P1) Sodium lauroyl glutamate (manufactured by Asahi Kasei Fine Chemicals Corporation, amino surfactant ALMS-P1) Potassium cocoyl glycinate (manufactured by Ajinomoto Co., Inc., Amilite GCK-11) Potassium myristate (manufactured by Miyoshi Oil & Fat Co., Ltd., Cosmetic Soap MF-K) Sodium cocoyl methyl taurate (manufactured by NOF Corporation, Diamondpon K-SF)

[0023] (C) Corn starch Corn starch (manufactured by Nippon Starch Chemical Co., Ltd., corn starch ST-C) Other starches Potato starch (manufactured by Nippon Starch Chemical Co., Ltd., Japanese Pharmacopoeia potato starch ST-P) Tapioca starch (manufactured by Nurion Japan Co., Ltd., TAPIOCA PURE) Rice starch, tocopherol, glycerin, sorbitol, polyglyceryl-10 oleate (manufactured by Joetsu Starch Co., Ltd., Myalfa K)

[0024] Lactose (from milk) (MEGGLE, GranuLac 200) Magnesium aluminometasilicate (manufactured by Tomita Pharmaceutical Co., Ltd., Flowlite) Calcium silicate (manufactured by Fuji Chemical Industry Co., Ltd., Neusilin) Talc (manufactured by Fuji Talc Industry Co., Ltd., Talc FG106) Croscarmellose (manufactured by Rettenmaier Japan Co., Ltd., VIVASTAR CS 40 DI) Magnesium stearate (manufactured by NOF Corporation, Magnesium stearate-S)

[0025] "Evaluation method" The following evaluations were performed on the obtained tablet-shaped skin cleanser. The results of each evaluation are shown in Tables 1 to 3. ·Moldability The moldability of the tablet-shaped skin cosmetic was evaluated according to the following criteria by picking up the tablet-shaped skin cosmetic by hand and visually observing its appearance. ○: The tablet surface is shiny, without chips, and can maintain its tablet shape even after observation. ×: The tablet surface is powdery, has chips, or cannot maintain its tablet shape after observation.

[0026] · Disintegration property, usability After dividing the tablet-shaped skin cleanser in half, 1 mL of water was added, and it was allowed to stand for 5 seconds, and then foamed. The disintegration property and usability were evaluated according to the following criteria. Note that for those whose evaluation of either the formability or disintegration property was "×", the usability evaluation was not performed except for some cases. · Disintegration property <Evaluation criteria> ◎: It disintegrates during the 5-second standing. ○: It disintegrates when foamed. △: A small lump remains after foaming, but it is acceptable. ×: A lump remains after foaming. · Usability <Evaluation items> 1) Quick foaming property 2) Foam volume 3) Foam quality (fineness of the foam texture, elasticity of the foam) 4) Foam persistence <Evaluation criteria> Based on the tablet-shaped skin cleanser obtained in Example 9, one professional panelist evaluated as follows. Note that the skin cleanser of Example 9 had a quality without practical problems. ◎: Excellent. ○: Equivalent. △: Slightly inferior but acceptable. ×: Inferior.

Table 1

[0027]

Table 2

[0028]

Table 3

[0029] "Result" The tablet-shaped skin cleanser obtained in Examples 1 to 17 of the present invention was excellent in moldability, disintegratability, and usability. As shown in Comparative Examples 1 and 2, only the components (A) and (C) were inferior in moldability or disintegratability. As shown in Comparative Examples 3 to 9, when other starches were used instead of (C) corn starch, they tended to be inferior in moldability or disintegratability. Also, those without problems in moldability and disintegratability were inferior in usability. As shown in Comparative Examples 10 to 13, when a bulking agent other than starches was used, it was inferior in disintegratability.

[0030] As specific examples of the tablet-shaped skin cleanser, formulation examples are shown below. According to Formulation Examples 1 to 4, a tablet-shaped skin cleanser excellent in moldability, disintegratability, and usability could be obtained.

[0031] [Formulation Example 1] Tablet Facial Cleanser (700 mg, pressing 500 kg) Component Dosage (mass%) Potato Starch 5.0 Sodium Lauroyl Glutamate 7.0 Potassium Cocoyl Glycinate 8.5 Sodium Cocoyl Isethionate 4.5 Crystalline Cellulose 30.0 Corn Starch 22.3 Croscarmellose 22.0 Protease 0.1 Lipase 0.1 Magnesium Stearate 0.5

[0032] [Formulation Example 2] Tablet Facial Cleanser (700 mg, pressing 700 kg) Component Dosage (mass%) Sodium Lauroyl Glutamate 5.5 Potassium Cocoyl Glycinate 5.0 Sodium Cocoyl Isethionate 4.5 Potassium myristate 5.0 Crystalline cellulose 30.0 Corn starch 24.5 Croscarmellose 22.0 Tapioca starch 3.0 Magnesium stearate 0.5

[0033] [Formulation Example 3] Tablet Facial Cleanser (700 mg, compression 700 kg) Ingredient Content (mass%) Sodium lauroyl glutamate 2.0 Potassium cocooyl glycinate 8.5 Sodium lauroyl aspartate 3.0 Sodium cocooyl isethionate 4.5 Potassium myristate 2.0 Hydroxypropyl starch 1.0 Crystalline cellulose 30.0 Corn starch 23.5 Croscarmellose 22.0 Tapioca starch 3.0 Magnesium stearate 0.5

[0034] [Formulation Example 4] Tablet Facial Cleanser (700 mg, compression 600 kg) Ingredient Content (mass%) Sodium lauroyl glutamate 4.0 Sodium cocooyl methyl taurine 3.0 Potassium cocooyl glycinate 2.0 Sodium lauroyl aspartate 4.0 Sodium cocooyl isethionate 5.5 Hydroxypropyl starch 1.0 Crystalline cellulose 30.0 Corn starch 23.5 Potato starch 4.5 Croscarmellose 22.0 Magnesium stearate 0.5

Claims

1. A tablet-shaped skin cleanser containing (A) crystalline cellulose, (B) an anionic surfactant, and (C) corn starch.

2. The tablet-shaped skin cleanser according to Claim 1, wherein the mass ratio of component (A) to component (C) (A:C, total being 100) is 40 to 80:60 to 20.

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