Medical information processing apparatus, medical information processing method, and medical information processing program

Abstract

To improve the efficiency of diagnosis compared to before.SOLUTION: A medical information processing apparatus according to an embodiment comprises a first acquisition unit, an extraction unit, a first specification unit, a second specification unit, and a display control unit. The first acquisition unit acquires harmful event information indicating a harmful event occurring in a patient. The extraction unit extracts medication information indicating a medicine administered to the patient. The first specification unit specifies, from the medication information, a related medicine related to the occurrence of the harmful event. When there is the related medicine, the second specification unit specifies related image information related to the related medicine. The display control unit displays output information including the harmful event information, medication information, medicine information related to the medicine, and related image information.SELECTED DRAWING: Figure 1

Description

Technical Field

[0001] The embodiments disclosed in this specification and the drawings relate to a medical information processing apparatus, a medical information processing method, and a medical information processing program.

Background Art

[0002] For example, when a doctor administers a drug such as an anticancer agent having cardiotoxicity to a patient, it is recommended to perform regular cardiac function tests (cardiac function monitoring) before treatment, after the start of treatment, and during treatment. When cardiotoxicity occurs in a patient, the doctor checks various information such as the anticancer agent administered to the patient, adverse events such as heart damage caused by administering the anticancer agent, and imaging images showing the results of cardiac function tests, and makes a diagnosis for the patient. However, since the above-mentioned information is not associated, the doctor has to spend time on the diagnosis, so there is room for further improvement.

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0004] One of the problems to be solved by the embodiments disclosed in this specification and the drawings is to improve the efficiency of diagnosis as compared with the prior art. However, the problems to be solved by the embodiments disclosed in this specification and the drawings are not limited to the above problems. The problems corresponding to the respective effects of the respective configurations shown in the embodiments described later can also be positioned as other problems.

Means for Solving the Problems

[0005] The medical information processing apparatus according to the embodiment includes a first acquisition unit, an extraction unit, a first specification unit, a second specification unit, and a display control unit. The first acquisition unit acquires adverse event information indicating an adverse event that has occurred to a patient. The extraction unit extracts medication information indicating a medication administered to the patient. The first specification unit specifies a related medication related to the occurrence of the adverse event from the medication information. The second specification unit specifies related image information related to the related medication when there is a related medication. The display control unit displays output information including the adverse event information, the medication information, the medication information related to the medication, and the related image information.

Brief Description of the Drawings

[0006]

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Embodiment for Carrying Out the Invention

[0007] Hereinafter, embodiments of a medical information processing apparatus, a medical information processing method, and a medical information processing program will be described in detail with reference to the drawings. Note that the medical information processing apparatus, the medical information processing method, and the medical information processing program according to the present application are not limited by the embodiments shown below.

[0008] (Embodiment) FIG. 1 is a block diagram showing a medical information processing apparatus 10 according to an embodiment. For example, as shown in FIG. 1, the medical information processing apparatus 10 according to the present embodiment is communicably connected to a data storage device 20 via a network 30. Here, the network 30 includes, for example, an in-hospital LAN (Local Area Network) or WAN (Wide Area Network) installed in a hospital. Note that only the medical information processing apparatus 10 and the data storage device 20 are connected to the network 30 shown in FIG. 1, but actually, various other devices and systems are connected.

[0009] The data storage device 20 stores medical information (medical data) of patients and information such as various guidelines. Specifically, the data storage device 20 receives medical information data (raw data, medical images, analysis results, reports, etc.) from various devices and systems connected to the network 30, and stores the received medical information data in a storage circuit in its own device for storage.

[0010] In addition, the data storage device 20 stores the data of the information in the storage circuit within the device in accordance with operations for storing information such as guidelines and documents. For example, the data storage device 20 is realized by a PACS (Picture Archiving AND Communication System), a HIS (Hospital Information System), a RIS (Radiology Information System), or the like.

[0011] The medical information processing device 10 is, for example, a device operated by a doctor working in a hospital, and executes various processes for improving the efficiency of diagnosis by a doctor as compared with the conventional case. For example, when cardiotoxicity occurs in a patient, the doctor checks various information such as the anticancer agent administered to the patient, adverse events such as heart disorders caused by administering the anticancer agent, and imaging images showing the results of cardiac function tests, and diagnoses the patient. The medical information processing device 10 associates the above-described information, enables the doctor to check the associated information, and perform a diagnosis on the patient, thereby improving the efficiency of diagnosis as compared with the conventional case. For example, the medical information processing device 10 is realized by a computer device such as a personal computer (PC), a workstation, or a server.

[0012] As shown in FIG. 1, the medical information processing device 10 according to the present embodiment includes a communication interface 11, an input interface 12, a display 13, a storage circuit 14, and a processing circuit 15.

[0013] The communication interface 11 controls the transmission and communication of various data transmitted and received between the medical information processing device 10 and each device connected via the network 30. Specifically, the communication interface 11 is connected to the processing circuit 15, and transmits the data received from each device on the network 30 to the processing circuit 15, or transmits the data received from the processing circuit 15 to each device on the network 30. For example, the communication interface 11 is realized by a network card, a network adapter, a NIC (Network Interface Controller), or the like.

[0014] The input interface 12 receives input operations of various instructions and various information from the operator. Specifically, the input interface 12 is connected to the processing circuit 15, and converts the input operation received from the operator into an electrical signal and transmits it to the processing circuit 15. For example, the input interface 12 is realized by a trackball, a switch button, a mouse, a keyboard, a touch pad that performs an input operation by touching the operation surface, a touch screen in which a display screen and a touch pad are integrated, a non-contact input interface using an optical sensor, and a voice input interface, etc.

[0015] Note that in this specification, the input interface 12 is not limited to only those equipped with physical operation parts such as a mouse and a keyboard. For example, an electrical signal processing circuit that receives an electrical signal corresponding to an input operation from an external input device provided separately from the device and transmits this electrical signal to the control circuit is also included in the example of the input interface 12.

[0016] The display 13 displays various information and various data. Specifically, the display 13 is connected to the processing circuit 15, and displays various information and various data received from the processing circuit 15. For example, the display 13 is realized by a liquid crystal display, a CRT (Cathode Ray Tube) display, a touch panel, or the like. The display 13 is an example of a display unit.

[0017] The memory circuit 14 stores various data and various programs. Specifically, the memory circuit 14 is connected to the processing circuit 15, stores the data received from the processing circuit 15, or reads out the stored data and transmits it to the processing circuit 15. For example, the memory circuit 14 is realized by a semiconductor memory element such as a ROM (Read Only Memory), a RAM (Random Access Memory), a flash memory, a hard disk, an optical disk, etc. Note that the memory circuit 14 may be realized by a cloud computer connected to the medical information processing apparatus 10 via the network 30.

[0018] The processing circuit 15 controls the entire medical information processing apparatus 10. Specifically, the processing circuit 15 executes various processes for improving the efficiency of diagnosis by a doctor. For example, the processing circuit 15 controls the data exchange with devices on the network 30, the storage of data in the memory circuit 14, and various processes using the data.

[0019] For example, as shown in FIG. 1, in this embodiment, the processing circuit 15 of the medical information processing apparatus 10 executes a registration function 151, a first acquisition function 152, an extraction function 153, an alignment function 154, a first specification function 155, a determination function 156, a second acquisition function 157, a second specification function 158, a third acquisition function 159, and a display control function 160.

[0020] The registration function 151 registers adverse event information. The registration function 151 is an example of a registration unit. Specifically, the registration function 151, in cooperation with the input interface 12 operated by the operator, registers adverse event information indicating an adverse event that has occurred to a patient in the memory circuit 14. The adverse event information is, for example, a symptom indicating an adverse event of cardiotoxicity caused by an anticancer agent.

[0021] Here, the harmful event information registered by the registration function 151 in the memory circuit 14 will be described with reference to FIG. 2. FIG. 2 is a table showing an example of harmful event information according to the embodiment. As shown in FIG. 2, the harmful event information T1 is information including patient information containing the patient name, the occurred harmful event, and occurrence date and time information including the date and time when the patient developed cardiotoxicity.

[0022] The patient information includes the patient name and an identifier for identifying the patient. The occurred harmful event is not limited to the toxic myocarditis and reduced cardiac function shown in FIG. 2, and includes symptoms indicating harmful events of cardiotoxicity caused by anticancer drugs. For example, there are left ventricular dysfunction, myocardial ischemia, arrhythmia, toxic myocarditis, etc.

[0023] The harmful event information T1 is not limited to this, and may include, for example, severity information indicating the severity of the harmful event. The severity information is, for example, the criteria defined by CTCAE (Common Terminology Criteria for Adverse Events). Note that the severity information is not limited to this. The harmful event information T1 may include registration date and time information including the date and time when the registration function 151 registered it in the memory circuit 14.

[0024] Returning to FIG. 1, the first acquisition function 152 acquires harmful event information. The first acquisition function 152 is an example of the first acquisition unit. Specifically, the first acquisition function 152 acquires, from the memory circuit 14, harmful event information indicating the harmful event that occurred to the patient and registered by the registration function 151.

[0025] The extraction function 153 extracts medication information. The extraction function 153 is an example of the extraction unit. Specifically, the extraction function 153 extracts, from the memory circuit 14, medication information indicating the drugs administered to the patient based on the patient information included in the harmful event information acquired by the first acquisition function 152.

[0026] Here, the dosing information extracted by the extraction function 153 from the memory circuit 14 will be described with reference to FIG. 3. FIG. 3 is a table showing an example of dosing information according to the embodiment. As shown in FIG. 3, the dosing information T2 is information including patient information containing the patient name, a drug including drug information administered to the patient, and dosing date and time information including the dosing date and time when the drug was administered to the patient. The drug information administered to the patient is not limited to cyclophosphamide and doxorubicin shown in FIG. 3.

[0027] Returning to FIG. 1, the alignment function 154 aligns the prognostic period information. The alignment function 154 is an example of an alignment unit. Specifically, based on the dosing information extracted by the extraction function 153, the alignment function 154 aligns the prognostic period information associated with the drug included in the drug information from the drug detail information stored in the memory circuit 14.

[0028] Here, the prognostic period information aligned by the alignment function 154 will be described with reference to FIG. 4. FIG. 4 is a table showing an example of drug detail information according to the embodiment. As shown in FIG. 4, the drug detail information T3 is information including dosing information including the drug, adverse event information including adverse events, prognostic period information including the prognostic period from the date and time when the drug was administered to the patient until the occurrence of an adverse event is predicted, and image information associated with the drug. The image information associated with the drug includes the analysis results analyzed by another system, and the analysis results may include the original imaging image used during the analysis. The image information will be described later.

[0029] Returning to FIG. 1, the first specification function 155 specifies the drug related to the occurrence of an adverse event. The first specification function 155 is an example of a first specification unit. Specifically, the first specification function 155 specifies the related drug related to the occurrence of an adverse event from the dosing information. For example, the first specification function 155 specifies the related drug related to the occurrence of an adverse event based on the dosing information extracted by the extraction function 153 and the prognostic period information including the prognostic period from the date and time when the drug was administered to the patient until the occurrence of an adverse event is predicted, aligned by the alignment function 154.

[0030] For example, the first specific function 155 identifies related drug information including drugs caused by the occurrence of an adverse event from the administration date and time of the drug associated with the drug included in the dosing information shown in FIG. 3 and the omen period of the adverse event associated with the drug included in the drug detailed information T3 shown in FIG. 4. In the cases of FIGS. 3 and 4, the drug identified by the first specific function 155 is identified as doxorubicin. The related drug information includes the name of the drug and the efficacy regarding the drug. Note that the drug information is not limited to this.

[0031] The determination function 156 determines whether there is a drug related to the occurrence of an adverse event. The determination function 156 is an example of a determination unit. Specifically, the determination function 156 determines whether there is a drug identified by the first specific function 155. Here, when there is a drug identified by the first specific function 155, the determination function 156 determines that there is a drug related to the occurrence of an adverse event. On the other hand, when there is no drug identified by the first specific function 155, the determination function 156 determines that there is no drug related to the occurrence of an adverse event.

[0032] The second acquisition function 157 acquires image information. The second acquisition function 157 is an example of a second acquisition unit. Specifically, when the determination function 156 determines that there is a drug related to the occurrence of an adverse event, the second acquisition function 157 acquires, from the memory circuit 14, the image information of the patient who has been administered the drug related to the occurrence of the adverse event determined by the determination function 156.

[0033] Here, the image information acquired by the second acquisition function 157 will be described with reference to FIG. 5. FIG. 5 is a table showing an example of the image information according to the embodiment. As shown in FIG. 5, the image information T4 is information including patient information including the patient name, image type information including the image type of the patient, and imaging date and time information including the imaging date and time when the image was taken.

[0034] Note that the second acquisition function 157 may acquire a plurality of pieces of image information about the image information. The plurality of pieces of image information are, for example, the image information of a patient who has been administered a drug related to the occurrence of a harmful event and the image information of a patient for comparison with the image information of a patient who has been administered a drug related to the occurrence of the harmful event. The patient image information for comparison is also referred to as comparison image information. The comparison image information is, for example, information regarding the image data of a patient when no harmful event has occurred.

[0035] When there is a drug caused by the occurrence of a harmful event, the second specifying function 158 specifies related image information related to the drug. The second specifying function 158 is an example of the second specifying unit. Specifically, when there is a related drug, the second specifying function 158 specifies related image information related to the related drug. For example, the second specifying function 158 specifies related image information including the imaging image data captured within the prediction period acquired by the second acquisition function 157 based on the prediction period included in the prediction period information aligned by the alignment function 154.

[0036] In the case of FIGS. 4 and 5, since the imaging date and time shown in FIG. 5 included in the prediction period shown in FIG. 4 is "2023-7-13 13:00", the related image information specified by the second specifying function 158 is specified as the second MRI (Magnetic Resonance Imaging) image.

[0037] The third acquisition function 159 acquires the latest image information. The third acquisition function 159 is an example of the third acquisition unit. Specifically, when the determination function 156 determines that there is no drug related to the occurrence of a harmful event, the third acquisition function 159 acquires the latest image information of the patient in whom the harmful event has occurred from the memory circuit 14.

[0038] The display control function 160 displays output information. The display control function 160 is an example of a display control unit. Specifically, the display control function 160 causes the output information to be displayed on the display 13. For example, the display control function 160 displays, on the display 13, output information including harmful event information, dosing information, drug information regarding a drug, and related image information. Here, the output information will be described with reference to FIG. 6.

[0039] FIG. 6 is a diagram for explaining an example of output information according to the embodiment. The output information shown in FIG. 6 will be described as information used when, for the purpose of specifically explaining the present embodiment, after a patient is administered doxorubicin, toxic myocarditis occurs and a doctor diagnoses the patient with respect to the harmful event.

[0040] The output information 40 shown in FIG. 6 includes image information 50, dosing information 60, related drug information 70, and harmful event information 80. The image information 50 is the image information acquired by the second acquisition function 157. The image information 50 shown in FIG. 6 shows image data 51 included in the related image information and image data 52 included in the comparison image information. The dosing information shown in FIG. 6 is the dosing information extracted by the extraction function 153. The dosing information 60 shown in FIG. 6 indicates, for each drug, doxorubicin and avastin administered to the patient, by dots so that the administration date and time can be known.

[0041] The related drug information 70 is the related drug information specified by the first specifying function 155. The related drug information 70 shown in FIG. 6 indicates the drug name of doxorubicin administered to the patient. The harmful event information 80 is the harmful event information and severity information acquired by the first acquisition function 152. The harmful event information shown in FIG. 6 indicates the heart, which is the site where the harmful event of the patient occurred, marks 81 and 82 indicating the date and time when the patient was dosed, the name of the harmful event, the CTCAE score of the severity of the harmful event, and the prodromal period 83.

[0042] In addition, the adverse event information 80 of the output information 40 may indicate marks 511 and 521 indicating the dates and times when the image data 51 and 52 included in the image information 50 were captured. Thereby, for example, a doctor can improve the diagnostic efficiency compared to the prior art because the output information output by the medical information processing apparatus 10 associates various types of information such as drugs administered to a patient, adverse events, and imaging images showing the results of cardiac function tests for a patient in whom an adverse event has occurred.

[0043] In addition, when the determination function 156 determines that there is no drug related to the occurrence of an adverse event, the display control function 160 displays "no related drug". Then, when the determination function 156 determines that there is no drug related to the occurrence of an adverse event, the third acquisition function 159 displays the latest image information of the patient in whom the adverse event has occurred, acquired from the storage circuit 14.

[0044] FIG. 7 is a flowchart showing an example of the processing of the medical information processing apparatus 10 according to the embodiment. Note that this processing is started after an adverse event has occurred in a patient and the operator has registered adverse event information indicating the adverse event that has occurred in the patient in the storage circuit 14.

[0045] First, the first acquisition function 152 acquires adverse event information from the storage circuit 14 (step S71). Subsequently, the extraction function 153 extracts dosing information administered to the patient based on the patient information included in the adverse event information acquired by the first acquisition function 152 (step S72).

[0046] Subsequently, the alignment function 154 aligns the omen period information associated with the drug included in the drug information from the drug detailed information stored in the storage circuit 14 based on the dosing information extracted by the extraction function 153 (step S73). Subsequently, the first specifying function 155 specifies the drug responsible for the occurrence of the adverse event based on the dosing information extracted by the extraction function 153 and the omen period information aligned by the alignment function 154 (step S74).

[0047] The determination function 156 determines whether there is a drug related to the occurrence of an adverse event (step S75). Here, if there is no drug identified by the first identification function 155, the determination function 156 determines that there is no drug related to the occurrence of the adverse event (step S75: No), and proceeds to step S79. On the other hand, if there is a drug identified by the first identification function 155, the determination function 156 determines that there is a drug related to the occurrence of the adverse event (step S75: Yes), and proceeds to step S76.

[0048] In step S76, the second acquisition function 157 acquires, from the storage circuit 14, image information of a patient who has been administered a drug related to the occurrence of the adverse event determined by the determination function 156 (step S76). Subsequently, the second identification function 158 identifies, based on the prediction period included in the prediction period information aligned by the alignment function 154, relevant image information related to the occurrence of the adverse event, which was captured within the prediction period and acquired by the second acquisition function 157 (step S77).

[0049] Subsequently, the display control function 160 displays the output information (step S78). In step S79, when the determination function 156 determines that there is no drug related to the occurrence of the adverse event, the display control function 160 displays "No relevant drug" (step S79). And when the determination function 156 determines that there is no drug related to the occurrence of the adverse event, the third acquisition function 159 displays the latest image information of the patient in whom the adverse event occurred, acquired from the storage circuit 14 (step S80). When this process ends, the process performed by the processing circuit 15 of the medical information processing apparatus 10 ends.

[0050] As described above, according to the embodiment, the medical information processing apparatus 10 acquires adverse event information indicating an adverse event that occurred in a patient, extracts medication information indicating the drugs administered to the patient, identifies relevant drugs related to the occurrence of the adverse event from the medication information, and when there are relevant drugs, identifies relevant image information related to the relevant drugs, and displays output information including the adverse event information, the medication information, the drug information regarding the drugs, and the relevant image information.

[0051] Thus, for example, when a doctor diagnoses a patient with a harmful event, the output information output by the medical information processing device 10 associates various information such as the drug administered to the patient, the harmful event, and the imaging image showing the result of the cardiac function examination for the patient with the harmful event. Therefore, the doctor can improve the efficiency of diagnosis compared to the conventional method.

[0052] In addition, the medical information processing device 10 identifies relevant drugs based on the medication information and the prognostic period information including the prognostic period from the date and time of drug administration to the patient until the occurrence of the harmful event is predicted. Further, the medical information processing device 10 identifies relevant image information including the imaging image data captured within the prognostic period based on the prognostic period.

[0053] Thus, for example, the medical information processing device 10 identifies relevant drugs and imaging image data related to the harmful event from the prognostic period from the date and time of drug administration to the patient until the occurrence of the harmful event is predicted. Therefore, the doctor can improve the efficiency of diagnosis compared to the conventional method.

[0054] In addition, the harmful event information includes severity information indicating the severity of the harmful event. Thus, the doctor can grasp the severity of the harmful event, and therefore can improve the efficiency of diagnosis compared to the conventional method.

[0055] Note that the above-described embodiment can also be appropriately modified and implemented by changing a part of the configuration or function of the medical information processing device 10. Therefore, some modification examples according to the above-described embodiment will be described as other embodiments below. In the following, the points different from the above-described embodiment will be mainly described, and detailed description of the points common to the already described content will be omitted. Further, the modification examples described below may be implemented individually or in appropriate combination.

[0056] (First Modification Example) For example, after a doctor grasps the related drugs in the related drug information 70 included in the output information 40, the doctor may consider identifying an alternative drug to substitute for the related drug and administering the identified alternative drug to the patient. Therefore, in the medical information processing apparatus 10 according to the first modification example, the form of identifying an alternative drug will be described.

[0057] FIG. 8 is a block diagram showing the medical information processing apparatus 10 according to the first modification example. As shown in FIG. 8, the processing circuit 15 of the medical information processing apparatus 10 according to the first modification example includes a registration function 151, a first acquisition function 152, an extraction function 153, an alignment function 154, a first identification function 155, a determination function 156, a second acquisition function 157, a second identification function 158, a third acquisition function 159, a display control function 160, and a fourth acquisition function 161.

[0058] The fourth acquisition function 161 acquires input operation information. The fourth acquisition function 161 is an example of a fourth acquisition unit. Specifically, the fourth acquisition function 161 cooperates with the input interface 12 operated by the operator to acquire the input operation information for operating the output information 40. For example, the fourth acquisition function 161 acquires the input operation information for pressing the severity information (such as the CTCAE score of the severity as an example) of the adverse event information 80 included in the output information 40. Note that the input operation information is not limited to this, and for example, it can also be applied when the drug name of the related drug in the related drug information 70 is operated.

[0059] Based on the input operation information acquired by the fourth acquisition function 161, the first identification function 155 identifies an alternative drug to substitute for the related drug in which the adverse event corresponding to the input operation information has occurred. For example, the first identification function 155 acquires information related to drugs from the data storage device 20, and based on the input operation information acquired by the fourth acquisition function 161, identifies an alternative drug to substitute for the related drug in which the adverse event corresponding to the input operation information has occurred. Note that the information related to drugs may be stored in the storage circuit 14.

[0060] The display control function 160 updates the related drug information 70 included in the output information 40. Specifically, the display control function 160 adds the drug name related to the alternative drug identified by the first specific function 155 to the related drug information 70 and updates it to the related drug information 71. Then, the display control function 160 causes the output information 40 including the updated related drug information to be displayed on the display 13. Here, the updated output information 40 will be described with reference to FIG. 9.

[0061] FIG. 9 is a diagram for explaining an example of the output information 40 according to the first modification. To specifically explain this modification, the output information 40 shown in FIG. 9 will be described as being operated on the output information 40 after the doctor has confirmed the output information 40 shown in FIG. 6.

[0062] For example, after the doctor has confirmed the output information 40 shown in FIG. 6, the doctor may consider an alternative drug to doxorubicin, which is the related drug administered to the patient, shown in the related drug information 70. In this case, the CTCAE score 84 of the severity shown in FIG. 9 is pressed.

[0063] Then, the fourth acquisition function 161, in cooperation with the input interface 12 operated by the doctor, acquires the input operation information for pressing the CTCAE score 84 of the severity. Subsequently, the first specific function 155 acquires information related to the drug from the data storage device 20 and identifies an alternative drug to doxorubicin, which is the related drug corresponding to the CTCAE score 84 of the severity.

[0064] Subsequently, the display control function 160 adds the drug name related to the alternative drug to doxorubicin identified by the first specific function 155 to the related drug information 70, updates it to the related drug information 71, and causes the output information 40 including the updated related drug information 71 to be displayed on the display 13.

[0065] The updated related drug information 71 shown in FIG. 9 indicates the drug name of doxorubicin, a related drug administered to the patient, and the first drug, the second drug, and the third drug [!], which are alternative drugs to doxorubicin. Since attention should be paid to the combined use of the third drug with abastin administered to the patient, a caution [!] is attached for alert. Thus, for example, by checking the output information 40 in which the related drug information 71 is updated, a doctor can consider alternative drugs for the related drug, and therefore, the diagnostic efficiency can be improved compared to the prior art.

[0066] FIG. 10 is a flowchart showing an example of the processing of the medical information processing apparatus 10 according to the first modification. Note that this processing starts after the doctor operates the output information 40 after checking the output information 40 shown in FIG. 6.

[0067] The fourth acquisition function 161 acquires input operation information obtained by pressing the severity information (for example, the CTCAE score of the severity, etc.) of the adverse event information 80 included in the output information 40 (step S81). Subsequently, the first specification function 155 specifies an alternative drug that substitutes for the related drug in which the adverse event corresponding to the input operation information has occurred based on the input operation information acquired by the fourth acquisition function 161 (step S82).

[0068] Subsequently, the display control function 160 adds the drug name related to the alternative drug specified by the first specification function 155 to the related drug information 70 and updates it to the related drug information 71 (step S83). Then, the display control function 160 causes the display 13 to display the output information 40 including the updated related drug information 71 (step S84).

[0069] As described above, according to the first modification, the medical information processing apparatus 10 acquires input operation information obtained by pressing the severity information of the adverse event information 80 included in the output information 40, and based on the input operation information, specifies an alternative drug that substitutes for the related drug in which the adverse event corresponding to the input operation information has occurred. Then, the medical information processing apparatus 10 adds the drug name related to the specified alternative drug to the related drug information 70, updates it to the related drug information 71, and causes the display 13 to display the output information 40 including the updated related drug information 71.

[0070] Thus, for example, a doctor can consider alternative drugs for the relevant drug by checking the output information 40 in which the relevant drug information 71 has been updated, so that the efficiency of diagnosis can be improved as compared with the conventional case.

[0071] (Second Modified Example) For example, a doctor may check the prediction period for each severity level of the adverse event information 80 included in the output information 40. Therefore, in the medical information processing apparatus 10 according to the second modified example, a form of displaying the prediction period for each severity level will be described.

[0072] For example, the fourth acquisition function 161 acquires input operation information obtained by pressing the severity level information of the adverse event information 80 included in the output information 40 (for example, the CTCAE score of the severity level, etc.). For example, the first identification function 155 identifies a drug corresponding to the severity level information included in the input operation information acquired by the fourth acquisition function 161 from the dosing information T2 stored in the storage circuit 14.

[0073] The display control function 160 updates the prediction period included in the output information 40. Specifically, the display control function 160 updates the prediction period displayed in the output information 40 to the prediction period corresponding to the drug identified by the first identification function 155. Then, the display control function 160 causes the display 13 to display the output information 40 including the updated prediction period. Here, the updated output information 40 will be described with reference to FIG. 11.

[0074] FIG. 11 is a diagram for explaining an example of the output information 40 according to the second modified example. To specifically explain this modified example, the output information 40 shown in FIG. 10 will be described as being operated after the doctor has checked the output information 40 shown in FIG. 6.

[0075] For example, after checking the output information 40 shown in FIG. 6, a doctor may want to check the prediction period for each severity level of the adverse event information 80. In this case, the CTCAE score 85 of the severity level shown in FIG. 9 is pressed.

[0076] Subsequently, the fourth acquisition function 161, in cooperation with the input interface 12 operated by the doctor, acquires input operation information indicating that the severity CTCAE score 85 has been pressed. Subsequently, the first specification function 155 specifies doxorubicin corresponding to the severity CTCAE score 85 included in the input operation information acquired by the fourth acquisition function 161 from the dosing information T2 stored in the memory circuit 14.

[0077] Subsequently, the display control function 160 updates the predicted period 83 displayed in the output information 40 to the predicted period 86 corresponding to the doxorubicin specified by the first specification function 155, and causes the display 13 to display the output information 40 including the updated predicted period 86.

[0078] Thereby, for example, the doctor can check the predicted period for each severity information of the adverse event information 80 by checking the output information 40 in which the predicted period 86 is updated, so that the diagnostic efficiency can be improved as compared with the prior art.

[0079] FIG. 12 is a flowchart showing an example of the processing of the medical information processing apparatus 10 according to the second modification. This processing is assumed to start after the doctor has confirmed the output information 40 shown in FIG. 6 and then operated the output information 40.

[0080] The fourth acquisition function 161 acquires input operation information indicating that the severity information (for example, severity CTCAE score, etc.) of the adverse event information 80 included in the output information 40 has been pressed (step S91). Subsequently, the first specification function 155 specifies the drug corresponding to the severity information included in the input operation information acquired by the fourth acquisition function 161 from the dosing information T2 stored in the memory circuit 14 (step S92).

[0081] Subsequently, the display control function 160 updates the predicted period 83 displayed in the output information 40 to the predicted period 86 corresponding to the drug specified by the first specification function 155 (step S93). Then, the display control function 160 causes the display 13 to display the output information 40 including the updated predicted period 86 (step S94).

[0082] As described above, according to the second modification example, the medical information processing apparatus 10 acquires input operation information obtained by pressing the severity information of the adverse event information 80 included in the output information 40, and identifies a drug corresponding to the severity information included in the input operation information. Then, the medical information processing apparatus 10 updates the predicted period 83 displayed in the output information 40 to the predicted period 86 corresponding to the drug identified by the first identification function 155, and causes the display 13 to display the output information 40 including the updated predicted period 86.

[0083] Thereby, for example, the doctor can check the predicted period for each severity information of the adverse event information 80 by checking the output information 40 in which the predicted period 86 is updated, so that the diagnostic efficiency can be improved as compared with the conventional case.

[0084] (Third Modification Example) In the present embodiment, the adverse event has been described as a symptom related to cardiotoxicity caused by an anticancer agent, but it is not limited thereto. The adverse event is not limited to drugs such as anticancer agents, and the medical information processing apparatus 10 can be applied to drugs in which adverse events occur.

[0085] Note that in the above-described embodiments and modification examples, examples in which the registration unit, the first acquisition unit, the extraction unit, the alignment unit, the first identification unit, the determination unit, the second acquisition unit, the second identification unit, the third acquisition unit, the display control unit, and the fourth acquisition unit in this specification are realized by the registration function, the first acquisition function, the extraction function, the alignment function, the first identification function, the determination function, the second acquisition function, the second identification function, the third acquisition function, the display control function, and the fourth acquisition function of the processing circuit have been described. However, the embodiments are not limited thereto. For example, the registration unit, the first acquisition unit, the extraction unit, the alignment unit, the first identification unit, the determination unit, the second acquisition unit, the second identification unit, the third acquisition unit, the display control unit, and the fourth acquisition unit in this specification may be realized by only hardware, only software, or a combination of hardware and software, in addition to being realized by the registration function, the first acquisition function, the extraction function, the alignment function, the first identification function, the determination function, the second acquisition function, the second identification function, the third acquisition function, the display control function, and the fourth acquisition function described in the embodiments.

[0086] Also, the term "processor" used in the description of the above-described embodiments means, for example, a CPU (Central Processing Unit), a GPU (Graphics Processing Unit), or a circuit such as an Application Specific Integrated Circuit (ASIC), a Programmable Logic Device (for example, a Simple Programmable Logic Device (SPLD), a Complex Programmable Logic Device (CPLD), and a Field Programmable Gate Array (FPGA)).

[0087] Here, instead of storing the program in the storage circuit, it may be configured to directly incorporate the program into the circuit of the processor. In this case, the processor realizes its functions by reading and executing the program incorporated in the circuit. Also, each processor of the present embodiment is not limited to being configured as a single circuit for each processor, and may be configured as one processor by combining a plurality of independent circuits so as to realize its functions.

[0088] Here, the medical information processing program executed by the processor is provided by being pre-incorporated in a ROM (Read Only Memory), a storage circuit, or the like. Note that this medical information processing program may be provided by being recorded on a computer-readable non-transitory storage medium such as a CD (Compact Disk)-ROM, an FD (Flexible Disk), a CD-R (Recordable), or a DVD (Digital Versatile Disk) in a form installable or executable on these devices.

[0089] In addition, this medical information processing program may be stored on a computer connected to a network such as the Internet and provided or distributed by being downloaded via the network. For example, this medical information processing program is composed of modules including the above-described respective processing functions. As actual hardware, when the CPU reads and executes a medical image processing program from a storage medium such as a ROM, each module is loaded onto the main storage device and generated on the main storage device.

[0090] Also, in the above-described embodiments and modification examples, each component of each illustrated device is conceptually functional and does not necessarily have to be physically configured as illustrated. That is, the specific form of the dispersion or integration of each device is not limited to that illustrated, and all or a part of it can be functionally or physically dispersed or integrated in any unit according to various loads, usage situations, etc. Furthermore, each processing function performed by each device can be realized in whole or in any part by a CPU and a program analyzed and executed by the CPU, or can be realized as hardware by wired logic.

[0091] Also, among the respective processes described in the above-described embodiments and modification examples, all or part of the processes described as being automatically performed can be manually performed, or all or part of the processes described as being manually performed can be automatically performed by a known method. In addition, regarding the processing procedures, control procedures, specific names, and information including various data and parameters shown in the above document and drawings, they can be arbitrarily changed unless otherwise specified.

[0092] According to at least one of the embodiments described above, the diagnostic efficiency can be improved compared to the prior art.

[0093] Although some embodiments have been described, these embodiments are presented by way of example and are not intended to limit the scope of the invention. These embodiments can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the gist of the invention. These embodiments and their modifications are included in the scope and gist of the invention, as well as in the invention described in the claims and the equivalent scope thereof.

Description of Reference Numerals

[0094] 10…Medical information processing device, 11…Communication interface, 12…Input interface, 13…Display, 14…Memory circuit, 15…Processing circuit, 151…Registration function, 152…First acquisition function, 153…Extraction function, 154…Sorting function, 155…First identification function, 156…Judgment function, 157…Second acquisition function, 158…Second identification function, 159…Third acquisition function, 160…Display control function, 161…Fourth acquisition function

Claims

1. A first acquisition unit that acquires adverse event information indicating an adverse event that has occurred in a patient; An extraction unit that extracts medication information indicating a drug administered to the patient; A first identification unit that identifies a related drug associated with the occurrence of the adverse event from the medication information; a second identification unit that identifies related image information regarding the related drug when the related drug is present; a display control unit that displays output information including the adverse event information, the medication information, drug information related to the drug, and the related image information; A medical information processing device comprising:

2. The first identification unit identifies the relevant drug based on the medication information and predictive period information including a predictive period during which the occurrence of the adverse event is predicted from a date and time when the drug is administered to the patient. The medical information processing device according to claim 1 .

3. the second identification unit identifies the related image information including captured image data captured within the warning period based on the warning period. The medical information processing device according to claim 2 .

4. The adverse event information includes severity information indicating the severity of the adverse event. The medical information processing device according to claim 1 .

5. Obtaining adverse event information indicating an adverse event that occurred in a patient; extracting medication information indicative of medications administered to the patient; Identifying a relevant drug associated with the occurrence of the adverse event from the medication information; If there is a related drug, identifying related image information regarding the related drug; displaying output information including the adverse event information, the medication information, drug information regarding the drug, and the related image information; A medical information processing method comprising:

6. Obtaining adverse event information indicating an adverse event that occurred in a patient; extracting medication information indicative of medications administered to the patient; Identifying a relevant drug associated with the occurrence of the adverse event from the medication information; If there is a related drug, identifying related image information regarding the related drug; displaying output information including the adverse event information, the medication information, drug information regarding the drug, and the related image information; A medical information processing program that causes a computer to execute each process.

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