Anti-fungal agent

Abstract

To provide an anti-fungal agent that does not have the defect of easily causing discoloration around a processing object, that is appropriate for use in general households, and that is also excellent in a musty odor inhibitory effect and a musty odor deodorant effect.SOLUTION: There is provided an anti-fungal agent that includes one or two or more selected from the group consisting of menthanes, alcohols, aldehydes and esters. A musty odor generation inhibitory composition and a musty odor deodorant composition are also provided.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to an antifungal agent, a composition for inhibiting the generation of mold odor, and a composition for eliminating mold odor. [Background technology]

[0002] In recent years, housing such as apartments has become airtight, allowing moisture to accumulate indoors, creating an environment prone to mold growth. Mold prefers to grow in places with moisture, moderate temperatures, and nutrients. In ordinary homes, environments such as bathrooms, dressing rooms, toilets, air conditioners, ventilation fans, washing machines, closets, storage areas, windows, wallpaper, curtains, and mattresses are favored and easy habitats for mold. Therefore, measures to prevent mold growth in these places are desired.

[0003] A common method for preventing mold growth is to apply an antifungal agent to an object. Antifungal agents that have been used so far include, for example, those that use silver (Patent Document 1) and those that use a photocatalyst (Patent Document 2), which are inorganic antifungal agents. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Japanese Patent Application Laid-Open No. 2007-31857 [Patent Document 2] Japanese Patent Application Laid-Open No. 2001-245781 Summary of the Invention [Problem to be solved by the invention]

[0005] Inorganic antifungal agents such as those described in Patent Documents 1 and 2 have the drawback of easily discoloring the area around the treatment target, and therefore are not necessarily suitable for use in ordinary households.

[0006] Mold not only has an unpleasant appearance, but also causes a distinctive mold odor. Even a faint mold odor can be unpleasant to humans, so it is important for antifungal agents used in ordinary households not only to prevent mold growth but also to suppress and eliminate the mold odor. Therefore, the present invention aims to provide an antifungal agent that is suitable for use in ordinary households and does not have the drawback of easily discoloring the surrounding area of the object to be treated, and that has excellent mold odor suppression and deodorization effects. [Means for solving the problem]

[0007] The present inventors have conducted extensive research to find an antifungal agent that is also excellent in the effects of inhibiting and eliminating mold odors. As a result, they have found that a specific component or combination of components functions as an antifungal agent that not only has an excellent antifungal effect, but also has excellent effects of inhibiting and eliminating mold odors. They have also found that such an antifungal agent does not have the drawback of being prone to discoloration and is suitable for use in ordinary homes, particularly in bathrooms, changing rooms, toilets, air conditioning equipment (air conditioners, ventilation fans), washing machines, closets, closets, windows, wallpaper, curtains, mattresses, etc., and have completed the present invention.

[0008] That is, the present invention relates to the following. [1] An antifungal agent, characterized in that it contains one or more compounds selected from the group consisting of menthanes, alcohols, aldehydes, and esters. [2] The antifungal agent according to [1], wherein the menthanes are one or more selected from the group consisting of limonene, carveol, terpineol, menthol, thymol, 1,8-cineole, 1,4-cineole, and carvacrol. [3] The antifungal agent according to [1] or [2], characterized in that the alcohols are one or more selected from the group consisting of phenethyl alcohol, linalool, dihydromyrcenol, tetrahydrolinalool, benzyl alcohol and geraniol. [4] The antifungal agent according to any one of [1] to [3], wherein the aldehyde is one or more selected from the group consisting of citral, perillaldehyde, and cinnamaldehyde. [5] The antifungal agent according to any one of [1] to [4], characterized in that the ester is one or more selected from the group consisting of allyl hexanoate, allyl heptanoate, allyl octanoate, cinnamyl acetate, benzyl benzoate, and benzyl acetate. [6] The antifungal agent according to [1], characterized in that the antifungal agent is one or more selected from the group consisting of limonene, carveol, terpineol, menthol, thymol, 1,8-cineole, 1,4-cineole, carvacrol, phenethyl alcohol, linalool, dihydromyrcenol, tetrahydrolinalool, benzyl alcohol, geraniol, citral, perillaldehyde, cinnamaldehyde, allyl hexanoate, allyl heptanoate, allyl octanoate, cinnamyl acetate, benzyl benzoate, and benzyl acetate. [7] The antifungal agent according to any one of [1] to [6], characterized in that the source of mold is a bathroom, a dressing room, a toilet, an air conditioner, a ventilation fan, a washing machine, a closet, a storage room, a window, wallpaper, a curtain, or a mattress. [8] A composition for suppressing the generation of mold odor, comprising the compound according to any one of [1] to [7]. [9] A mold odor deodorizing composition containing the compound according to any one of [1] to [8].

[10] The composition according to any one of [1] to [9], which is in the form of a spray product, a liquid, a tablet, a capsule or a drug-impregnated body. [Effects of the Invention]

[0009] According to the present invention, it is possible to provide an anti-mold agent, a mold odor generation inhibiting composition, and a mold odor deodorizing composition that are suitable for use in ordinary households, particularly in bathrooms, changing rooms, toilets, air conditioners, ventilation fans, washing machines, closets, storage rooms, windows, wallpaper, curtains, mattresses, etc., and that have excellent mold prevention effects as well as excellent mold odor generation inhibiting effects and mold odor deodorizing effects, without the drawback of easily discoloring the surroundings of the object to be treated. DETAILED DESCRIPTION OF THE INVENTION

[0010] The antifungal agent, mold odor suppressing composition, and mold odor eliminating composition of the present invention will be described below. However, the present invention is not intended to be limited to the configurations described in the embodiments described below.

[0011] The menthanes contained in the antifungal agent, mold odor generation-inhibiting composition, and mold odor deodorizing composition used in the present invention include aromatic menthane, unsaturated aliphatic menthane, saturated aliphatic menthane, etc. Examples include, but are not limited to, compounds in which at least one hydrogen atom bonded to a carbon atom of p-menthane represented by the following chemical formula (I) is substituted with a substituent, and compounds in which at least one single bond of p-menthane is substituted with a double bond. Examples of the substituent include, but are not limited to, a hydroxyl group, an ethereal oxygen atom (-O-), an amino group, an alkyl group, a carboxyl group, an acyl group, an ester group, an amide group, etc.

[0012] [ka] More specific examples of such menthanes include aromatic menthanes such as thymol and carvacrol; limonenes such as d-limonene; terpineols such as α-lupineol; carvone such as carveol, perillaldehyde, menthone, d-carvone and l-carvone; unsaturated aliphatic menthanes such as pinocarvone, pinocarveol, piperitone, piperitenone, pulegone and dihydrocarvone; menthols such as p-menthane-3,8-diol and l-menthol; and saturated aliphatic menthanes such as menthyl acetate, 1,8-cineole, 1,4-cineole and p-menthane, but are not limited to these. Among these menthanes, it is preferable to contain one or more types selected from the group consisting of limonene such as d-limonene, terpineol such as α-terpineol, carveol, p-menthane-3,8-diol, menthol such as l-menthol, menthyl acetate, 1,8-cineole, 1,4-cineole, menthone, thymol, carvone such as d-carvone and l-carvone, pinocarveol, piperitone, piperitenone, pulegone, and dihydrocarvone, more preferably one or more types selected from the group consisting of limonene, terpineol, carveol, menthol, 1,8-cineole, 1,4-cineole, thymol, and carvacrol, and even more preferably carveol. Note that, when the menthanes of the present invention include optical isomers based on asymmetric carbons or geometric isomers based on double bonds, they may be each of these isomers or any mixture thereof. In addition, in the present invention, menthanes having a hydroxyl group are treated as menthanes rather than alcohols, menthanes having an ester structure are treated as menthanes rather than esters, and menthanes having an aldehyde structure are treated as menthanes rather than aldehydes.

[0013] Alcohols contained in the mildew inhibitor, mildew odor generation inhibiting composition, and mildew odor deodorizing composition used in the present invention include, but are not limited to, dihydromyrcenol, linalool, ethyl linalool, dihydrolinalool, nerol, geraniol, citronellol, myrcenol, lavandulol, oct-1-en-3-ol, 1-decanol, nonyl alcohol, 1-nonanol, 2-nonanol, 1-octanol, 2-octanol, 1-heptanol, phenethyl alcohol, phenol, salicylic alcohol, tetrahydrolinalool, benzyl alcohol, and the like. Among these alcohols, it is preferred to contain one or more selected from the group consisting of phenethyl alcohol, linalool, dihydromyrcenol, tetrahydrolinalool, benzyl alcohol and geraniol, and more preferred to contain dihydromyrcenol.In addition, when the alcohol of the present invention has optical isomers based on asymmetric carbon or geometric isomers based on double bond, it can be each of them or any mixture thereof.

[0014] The aldehydes contained in the antifungal agent, mold odor generation inhibiting composition, and mold odor deodorizing composition used in the present invention are, for example, saturated or unsaturated alkyl aldehydes, aromatic aldehydes, and the like. Examples of the alkyl aldehyde include saturated alkyl aldehydes such as nonanal, hexanal, octanal, decanal, undecanal, dodecanal, 6-methoxy-2,6-dimethyloctanal, heptanal, phenylacetaldehyde, phenylpropylaldehyde, cyclamen aldehyde, helional, and (3-isopropylphenyl)butanal; and saturated alkyl aldehydes such as citral, 9-decenal, 2,6-dimethylhept-5-enal, and 2,4- Examples of the unsaturated alkyl aldehyde include, but are not limited to, dimethylcyclohex-3-enecarbaldehyde, (2E,6Z)-nona-2,6-dienal, 3-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)propanal, (Z)-dec-4-enal, (E)-dec-4-enal, 4-vinylcyclohex-1-enecarbaldehyde, and bicyclo[2.2.2]oct-5-ene-2-carboxaldehyde. Examples of aromatic aldehydes include, but are not limited to, vanillin, cuminaldehyde, cinnamaldehyde, amyl cinnamaldehyde, hexyl cinnamaldehyde, heliotropin, anisaldehyde, ethyl vanillin, and 4-methoxybenzaldehyde. Among these aldehydes, it is preferable to contain one or more selected from the group consisting of citral, nonanal, phenylacetaldehyde, perillaldehyde, and cinnamaldehyde, and it is more preferable to contain cinnamaldehyde. Note that, when the aldehydes in the present invention include optical isomers based on asymmetric carbons or geometric isomers based on double bonds, they may be each of them or any mixture thereof.

[0015] The esters contained in the antifungal agent, mold odor generation inhibiting composition, and mold odor deodorizing composition used in the present invention are preferably one or more types selected from the group consisting of allyl esters, benzyl esters, and phenyl esters. Examples of such allyl esters include saturated fatty acid allyl esters such as allyl heptanoate, allyl hexanoate, allyl octanoate, and allyl pentanoate; aromatic carboxylic acid allyl esters such as anthranilic acid allyl ester and benzoic acid allyl ester; and isothiocyanic acid allyl ester. Examples of benzyl esters include benzyl acetate, benzyl propionate, benzyl butanoate, benzyl benzoate, nicotinic acid benzyl ester, 4-methylbenzyl acetate, 2,4-dimethylbenzyl acetate, cuminyl acetate, 4-methoxybenzyl propionate, 2-acetyl-but-2-enedioic acid 1-benzyl ester 4-ethyl ester, 2-octylidene-malonic acid dibenzyl ester, carbonate benzyl ester phenethyl ester, carbonate benzyl ester hex-3-enyl ester, carbonate benzyl ester des-9-enyl ester, and the like. Examples of phenyl esters include, but are not limited to, saturated fatty acid phenyl esters such as phenyl acetate, phenyl hexanoate, and phenyl heptanoate. Fatty acids include those having 1 to 10 carbon atoms. Among these esters, it is preferable to contain one or more esters selected from the group consisting of allyl hexanoate, allyl heptanoate, allyl octanoate, cinnamyl acetate, benzyl benzoate, and benzyl acetate, and it is more preferable to contain one or more esters selected from the group consisting of allyl hexanoate, allyl heptanoate, and allyl octanoate. Note that, when the esters of the present invention contain optical isomers based on asymmetric carbons or geometric isomers based on double bonds, they may be each of these isomers or any mixture thereof.

[0016] In addition to the above components, the antifungal agent, mold odor generation inhibiting composition, and mold odor deodorizing composition used in the present invention can also contain, as appropriate, mold-killing components, insecticidal components, repellents, fragrances, deodorizers, stabilizers, antistatic agents, antifoaming agents, excipients, etc., as long as they do not deviate from the gist of the present invention. Examples of fungicide ingredients include phenolic fungicide ingredients such as isopropylmethylphenol (IPMP), triclosan, methylparaben, ethylparaben, propylparaben, butylparaben, 4-chloro-3,5-dimethylphenol, orthophenylphenol, o-cresol, m-cresol, and p-cresol; benzalkonium salts such as benzalkonium chloride, benzalkonium methosulfate, and benzalkonium organic acid salts; benzethonium salts such as benzethonium chloride, benzethonium methosulfate, and benzethonium organic acid salts; cetylpyridinium salts such as cetylpyridinium chloride, cetylpyridinium methosulfate, and cetylpyridinium organic acid salts; didecyldimethylammonium salts such as didecyldimethylammonium chloride and decyldimethylammonium methosulfate; dilauryldimethylammonium salts such as dilauryldimethylammonium chloride and dilauryldimethylammonium methosulfate; distearyldimethylammonium salts such as dilauryldimethylammonium chloride and dilauryldimethylammonium methosulfate; distearyldimethylammonium salts such as distearyldimethylammonium chloride and distearyldimethylammonium methosulfate, and 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dibromide, 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dichloride, and 1,4-bis[3,3'-(1-decylpyridinium)methyloxy]butane dimethosulfate. cationic surfactant-based fungicidal ingredients such as hydroxybutane salts, biguanide-based fungicidal ingredients, azole-based fungicidal ingredients such as tebuconazole and enilconazole, fruit seed extract-based fungicidal ingredients such as grapefruit seed extract, persimmon seed extract and grape seed extract, glycerin mono fatty acid ester-based fungicidal ingredients such as monolaurin, monocaprin and monocaprylin, chlorhexidine salts such as chlorhexidine gluconate and chlorhexidine hydrochloride, and chlorhexidine-based fungicidal ingredients such as chlorhexidine,Octadecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, dodecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, dodecyldiisopropyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, tetradecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldimethyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, pentadecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride, hexadecyldimethyl(3-triethoxysilylpropyl)ammonium Examples of suitable fungicides include silicon-based fungicides such as hexadecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, hexadecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride, octadecyldiethyl(3-triethoxysilylpropyl)ammonium chloride, and octadecyldi-n-propyl(3-triethoxysilylpropyl)ammonium chloride; carboxylic acid-based fungicides such as benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyldiethylaminoglycine, and polylysine, or salts thereof; and silver-based fungicides such as dehydroacetic acid, chloramine, 3-iodo-2-propyl-N-butylcarbamate (IPBC), phenoxyethanol, and silver zeolite; zinc pyrithione, thiamine lauryl sulfate, milt protein, and hydroxyalkyl chitosan or salts thereof. Insecticidal ingredients include transfluthrin, metofluthrin, profluthrin, telallethrin, furamethrin, empenthrin, momfluorothrin, dimefluthrin, mepafluthrin, heptafluthrin, fenothrin, cyphenothrin, permethrin, cypermethrin, cyfluthrin, bifenthrin, fenpropathrin, tralomethrin, etofenprox, imiprothrin, allethrin, phthalthrin, prallethrin, resmethrin,Examples of pesticides include pyrethroid compounds such as pyrethrins and natural pyrethrins, silicon compounds such as silafluofen, organophosphorus compounds such as dichlorvos and fenitrothion, carbamate compounds such as propoxur, neonicotinoid compounds such as dinotefuran, imidacloprid, and clothianidin, fipronil, indoxacarb, brofuranilide, and methoxadiazone. Repellents include DEET, ethyl butylacetylaminopropionate (IR3535), and icaridin. Examples of fragrances include orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, lemon eucalyptus oil, citronella oil, lime oil, yuzu oil, jasmine oil, cypress oil, green tea essential oil, peppermint oil, and aromatic components such as α-pinene, as well as fragrance components containing leaf alcohol and leaf aldehyde, known as "green fragrances." In addition, when optical isomers based on asymmetric carbons or geometric isomers based on double bonds of each component exist, each of these may be used individually or in any mixture.

[0017] In the present invention, "mold prevention" refers to the effect of stopping or inhibiting the growth of new mold that adheres after treatment, but does not require the killing of mold. "Mold-killing" refers to the effect of killing mold that is present at the time of treatment, but does not require the effect on new mold that adheres after treatment.

[0018] The antifungal agent of the present invention or a composition containing the same may be the above-mentioned compound itself, or may be a mixture of the compound with an additive such as an excipient, a carrier, etc. In addition to the above-mentioned additives, any additive that has been well established in the past may be used in the present invention.

[0019] When the antifungal agent, mold odor generation inhibiting composition, and mold odor deodorizing composition used in the present invention are liquid or foam formulations, the above-mentioned components are preferably dispersed in a solvent. By dispersing the above-mentioned components in a solvent, mold generation can be effectively inhibited. The solvent that can be used in the present invention may be aqueous or oil-based, and is not particularly limited. Examples of the solvent include water, alcohol solvents having 1 to 4 carbon atoms, such as methanol, ethanol, 1-propanol, 2-propanol (IPA), 1-butanol, and 2-butanol, preferably alcohol solvents having 2 to 3 carbon atoms, such as ethanol, 1-propanol, and 2-propanol (IPA), hydrocarbon solvents such as hexane, xylene, toluene, kerosene, petroleum benzine, normal paraffin, and isoparaffin, ketone solvents such as acetone and methyl ethyl ketone, glycol ether solvents having 3 to 10 carbon atoms, ketone solvents such as methyl isobutyl ketone and acetone, diol solvents such as methyl ethyl ketone ... Halogen-based solvents such as chloromethane and dichloroethane, ether-based solvents such as tetrahydrofuran, dioxane, and diethyl ether, glycol-based solvents such as propylene glycol, 1,3-butylene glycol, glycerin, dipropylene glycol, benzyl glycol, tripropylene glycol, and hexylene glycol, glycol ether-based solvents such as diethylene glycol monobutyl ether, dipropylene glycol monobutyl ether, and tripropylene glycol monomethyl ether, phenoxyethanol, and 2-(2-ethoxyethoxy)ethanol, triacetin, and triethyl citrate may also be used. Additionally, ester-based solvents such as methyl acetate, ethyl acetate, butyrate esters, isobutyrate esters, and formates may also be used. Such ester-based solvents preferably have a total of 16 to 20 carbon atoms, and preferred examples thereof include, but are not limited to, isopropyl myristate, butyl myristate, hexyl laurate, and isopropyl palmitate. The above solvents may be used alone or in combination of two or more. The content of the solvent is preferably 500 to 50,000 mass %, more preferably 1,000 to 25,000 mass %, relative to 100 mass % of the antifungal agent used in the present invention. The solvent may further contain additives such as conventional surfactants, emulsifiers, dispersants, spreading agents, wetting agents, stabilizers, and propellants, and may be used in the form of a coating agent, adhesive agent, emulsion, dispersant, suspension, aerosol, lotion, paste, cream, microemulsion, and the like. Preferred surfactants for use in the present invention include, but are not limited to, nonionic surfactants such as polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ethers such as polyoxyethylene higher alkyl ethers (polyoxyethylene lauryl ether, polyoxyethylene oleyl ether, etc.), polyoxyethylene fatty acid esters such as polyoxyethylene higher fatty acid esters (polyoxyethylene laurate, polyoxyethylene oleate, etc.), and polyoxyethylene polyoxypropylene alkyl ethers; and alkylamine oxide surfactants such as higher alkylamine oxide surfactants (laurylamine oxide, stearylamine oxide, lauric acid amidopropyldimethylamine oxide, etc.).

[0020] The antifungal agent, mold odor suppressing composition, and mold odor deodorizing composition of the present invention may also be used as a spray product, such as a spray form that does not require a propellant, by filling the compound itself or a dispersion of the compound in a solvent into a trigger-type or pump-type spray container, or as an aerosol form that is filled into a pressure-resistant container and blended with a propellant. In the latter case, the compound itself or a dispersion of the compound in a solvent is placed in an aerosol container as an aerosol concentrate, and the propellant can be, but is not limited to, liquefied gases such as dimethyl ether, liquefied petroleum gas (LPG), and hydrofluoroolefins, or compressed gases such as nitrogen gas, carbon dioxide, nitrous oxide, and compressed air, and the aerosol of the present invention can be provided by filling the container under pressure. The blend ratio (volume ratio) of the aerosol concentrate to the propellant is preferably 1 / 99 to 70 / 30, and more preferably 3 / 97 to 60 / 40. The concentration of the antifungal agent in the aerosol concentrate is not particularly limited, but is preferably 0.1 to 70 w / v%, more preferably 0.5 to 30 w / v. The aerosol may be formulated as either an aqueous aerosol or an oil-based aerosol. The number, dimensions, and shape of the nozzles in the spray or aerosol form are not particularly limited.

[0021] The aerosol can be made into a metered dose aerosol by providing a metered dose valve, and from the viewpoint of convenience, it is preferable to provide a metered dose valve. The volume of the metered dose chamber of the metered dose valve is not particularly limited, but is generally 0.05 to 3.0 mL, and from the viewpoint of operability, it is preferably 0.1 to 2.0 mL. The number of sprays per treatment can be adjusted appropriately depending on the application, etc., but is usually 1 to 8 sprays per treatment, and from the viewpoint of effective treatment, it is preferable to spray 2 to 6 sprays per treatment.

[0022] The antifungal agent, mold odor generation inhibiting composition, and mold odor deodorizing composition of the present invention may also be in the form of a tablet. Tablets can be produced based on methods conventionally known in the art. For example, examples of auxiliary agents used in tablet production include solid carriers and organic materials. Examples of solid carriers include fine powders or powders such as clays (kaolin, bentonite, etc.) and talcs. In addition, components known in the art, such as adhesives, binders, thickeners, and dispersants, may be used as appropriate, including casein, gelatin, starch powder, carboxymethyl cellulose, polyvinyl alcohol, polyethylene glycol, sodium polyacrylate, gum arabic, and xanthan gum.

[0023] The antifungal agent, mold odor generation inhibiting composition, and mold odor deodorizing composition of the present invention may also be in the form of a capsule. Capsules can be produced based on methods conventionally known in the art. For example, capsules obtained by encapsulating an antifungal agent with a film or capsules obtained by filling a porous material with an antifungal agent can be used. The capsules may be, but are not limited to, water-soluble, sustained-release, or disintegrating types. Of these, sustained-release capsules are preferred because they can exert the antifungal effect, mold odor generation inhibiting effect, and mold odor deodorizing effect for a longer period of time. Examples of porous materials include inorganic porous materials such as silicates, silica, and zeolites, but are not limited to these.

[0024] The antifungal agent, mold odor generation-inhibiting composition, and mold odor-deodorizing composition of the present invention may be incorporated into a gel or beads. By incorporating the antifungal agent into a gel or beads, the antifungal agent of the present invention can exert its antifungal effect, mold odor generation-inhibiting effect, and mold odor-deodorizing effect for a longer period of time. Beads also include gel beads. Gels and beads can be produced by methods conventionally known in the art. For example, a gelling agent may be used to prepare the gel. Examples of such gelling agents include, but are not limited to, carrageenan, xanthan gum, gellan gum, gelatin, aluminum octylate, and 12-hydroxystearic acid. Furthermore, beads can be prepared, for example, by imparting the liquid antifungal effect, mold odor generation-inhibiting effect, and mold odor-deodorizing effect of the present invention to beads made of a water-absorbent polymer. Furthermore, examples of such water-absorbent polymers include acrylic acid-based water-absorbent polymers. Examples of acrylic acid-based water-absorbing polymers include, but are not limited to, acrylic acid / acrylate copolymers (such as acrylic acid / sodium acrylate copolymers and acrylic acid / potassium acrylate copolymers) and copolymers of acrylamide / acrylic acid or its salts.

[0025] The antifungal agent, mold odor generation-inhibiting composition, and mold odor deodorizing composition of the present invention may be contained in a chemical-impregnated body. Such a chemical-impregnated body containing the above-mentioned antifungal agent, mold odor generation-inhibiting composition, and mold odor deodorizing composition is also a preferred embodiment of the present invention. The chemical-impregnated body is, for example, an absorbent carrier impregnated with a chemical. Examples of such carriers include, but are not limited to, pulp nonwoven fabric, felt, liquid-absorbing sponge, paper, and fiber aggregates. Furthermore, to increase the thickness of the carrier, multiple sheets of thin pulp nonwoven fabric, felt, etc. may be laminated, or multiple fiber aggregates may be used. To efficiently absorb the chemical while maintaining its shape, the carrier may have a web formed on its surface by a spunlace method or may be embossed.

[0026] Examples of molds that are targeted by the antifungal agent of the present invention include black mold, sooty mold, red mold, Penicillium diffusum, Aspergillus oryzae, Aspergillus niger, and Adzuki mold, and the mold odors that are targeted by the mold odor generation-inhibiting composition and mold odor-deodorizing composition of the present invention are mold odors caused by black mold, sooty mold, Penicillium diffusum, Aspergillus oryzae, Aspergillus niger, and Adzuki mold, etc. Sources of these molds include bathrooms, changing rooms, toilets, air conditioners, ventilation fans, washing machines, closets, closets, windows, wallpaper, curtains, mattresses, etc. In particular, the antifungal agent is suitable for use in preventing mold generation, preventing mold odor generation, and deodorizing mold odors in humid environments such as bathrooms, changing rooms, air conditioning equipment (air conditioners, ventilation fans), and washing machines, and is particularly suitable for use in bathrooms.

[0027] It should be noted that the present invention is not limited to the above-described embodiments, and various modifications are possible within the scope of the claims, and embodiments obtained by appropriately combining the technical means disclosed in different embodiments are also included in the technical scope of the present invention. The effects of the present invention will be explained in more detail below using examples, but the present invention is not limited to these examples. [Example]

[0028] (Test Example 1: Antifungal Efficacy Test) A 3 x 2.3 cm Kimwipe (manufactured by Nippon Paper Crecia) was placed at the bottom of a sterilized 50 mL centrifuge tube, and 10 μL of each of the components from Examples 1 to 13 and Comparative Example 1 was dropped onto the Kimwipe. A 1:1 mixture of Cladsporium cladosporioides spore dispersion and GP medium diluted 2-fold with sterile water was dropped into a sterilized microtube (40 μL), which was then placed in the centrifuge tube, the tube's lid was closed, and the tube was left at 25°C for one week. A control sample was also prepared in the same manner, but without the test solution. In Comparative Example 1, commercially available cypress oil containing hinokitiol as its main component was used.

[0029] After one week, the growth of mold was visually observed in Examples 1 to 13 and Comparative Example 1, and the mold prevention effect was evaluated according to the following evaluation criteria (the test results are shown in Table 1). (Evaluation criteria) A: The growth of mold is barely visible to the naked eye. B: The amount of mold growth is significantly less than that of the control. C: The amount of mold growth is slightly less than that of the control. D: The amount of mold growth is equivalent to that of the control. [Table 1]

[0030] (Test example 2: Antifungal efficacy test in the bathroom) 1. Preparation of test aerosol products Example 14 An aerosol concentrate was prepared by dissolving cinnamaldehyde (10.0 w / v % in the aerosol concentrate) in ethanol, an organic solvent. 15 mL of the aerosol concentrate (a) and 15 mL of liquefied petroleum gas (b) (0.44 MPa) as a propellant were pressurized and filled into an aerosol container (pressure-resistant container) with a 1.0 mL spray capacity and a metered-volume spray valve, so that the volume ratio (a / b) was 50 / 50, to obtain the test aerosol product of Example 14.

[0031] Example 15 An aerosol concentrate was prepared by dissolving phenethyl alcohol (10.0 w / v% in the aerosol concentrate) in ethanol, an organic solvent. 15 mL of the aerosol concentrate (a) and 15 mL of liquefied petroleum gas (b) (0.44 MPa) as a propellant were pressurized and filled into an aerosol container (pressure-resistant container) with a 1.0 mL spray capacity and a metered-volume spray valve, so that the volume ratio (a / b) was 50 / 50, to obtain the test aerosol product of Example 15.

[0032] (Comparative Example 2) A commercially available cypress oil (10.0 w / v% in the aerosol concentrate), whose main component is hinokitiol, was dissolved in ethanol, an organic solvent, to prepare a stock aerosol solution. 15 mL of the stock aerosol solution (a) and 15 mL of liquefied petroleum gas (b) (0.44 MPa) as a propellant were pressurized and filled into a 1.0 mL aerosol container (pressure-resistant container) equipped with a metered dose valve, so that the volume ratio (a / b) was 50 / 50, to obtain the test aerosol product of Comparative Example 2.

[0033] 2. Preparation of test bacterial solution Cladosporium cladosporioides mold spores grown on PDA medium were dispersed in an aqueous solution of dioctyl sodium sulfosuccinate, diluted 100-fold with sterilized water, and mixed with 1 / 2 GP medium at a 1:1 ratio to prepare the test fungus solution.

[0034] 3. Test Method Length 1.2m x width 1.6m x height 1.9m (volume 3.6m 3 A 6cm diameter plastic petri dish with its lid open was placed in the ceiling corner of a modular bathroom (approx. 1000 m²). From a position 50cm vertically, 50cm horizontally, and 40cm vertically downward from the ceiling corner, the test aerosol product prepared in Example 14 was pumped diagonally upward at a 45-degree angle toward the plastic petri dish in the ceiling corner. After leaving it for 15 minutes, the room was ventilated, and the petri dish was recovered. 100µL of a Cladsporium cladosporioides spore dispersion mixed 1:1 with GP medium diluted 2-fold with sterile water was added to the petri dish and cultured at 25°C under humidified conditions for one week. A control without the test solution was also prepared. Similar tests were also conducted on the test aerosol products prepared in Example 15 and Comparative Example 2.

[0035] After one week, the growth of mold on the surfaces treated with Examples 14, 15, and Comparative Example 2 was visually observed, and the mold-preventing effect was evaluated according to the following criteria (the test results are shown in Table 2). (Evaluation criteria) A: The growth of mold is barely visible to the naked eye. B: The amount of mold growth is significantly less than that of the control. C: The amount of mold growth is slightly less than that of the control. D: The amount of mold growth is equivalent to that of the control. [Table 2]

[0036] As a result of the test, the test aerosol products of Examples 14 and 15 showed excellent antifungal effects. Furthermore, the test aerosol products of Examples 14 and 15 did not discolor the surrounding area of the treated object. On the other hand, the test aerosol product of Comparative Example 2 showed almost no antifungal effect, with the amount of mold growth being the same as that of the control example.

[0037] (Test Example 3: Test to suppress mold odor generation and eliminate mold odor in the bathroom) Length 1.2m x width 1.6m x height 1.9m (volume 3.6m 3 In a unit bath (approximately 100cm x 100cm), the test aerosol product of Example 14 was pumped four times at a 45-degree angle from the entrance toward the wall, and the generation of mold odor was confirmed after three days. As a result, compared to the mold odor generated after three days in an untreated unit bath, the generation of mold odor was significantly reduced, demonstrating the mold odor generation suppression effect and mold odor elimination effect. [Industrial Applicability]

[0038] The antifungal agent obtained by the present invention has excellent antifungal effects, mold odor generation suppression effects, and mold odor deodorization effects without the drawback of discoloring the surroundings of the treated object. Furthermore, by using this antifungal agent, a mold odor generation suppression composition and a mold odor deodorizer can also be provided.

Claims

1. An antifungal agent containing phenethyl alcohol and / or cinnamaldehyde, It is in the form of a spray product, liquid, tablet, capsule or drug-impregnated body, The mildew source is any one of a bathroom, a dressing room, a toilet, an air conditioner, a ventilation fan, a washing machine, a closet, a storage closet, a shoe cabinet, a window, wallpaper, a curtain, and a mattress (excluding cases where the mildew source contains at least one compound selected from compounds represented by the following general formula (1)). R １ -O(AO) ｎ H (1) [In the formula, R １ is an alkyl group having 6 to 11 carbon atoms, A is an alkylene group having 2 to 3 carbon atoms, and n is a number from 1 to 3 indicating the average number of moles added, and the n As may be the same or different, except for ethylene glycol monohexyl ether.

2. An antifungal agent containing phenethyl alcohol and / or cinnamaldehyde, It is in the form of a spray product, liquid, tablet, capsule or drug-impregnated body, The antifungal agent is characterized in that the source of mold is any one of a bathroom, a toilet, an air conditioner, a ventilation fan, and a washing machine.

3. An antifungal agent containing carveol, A mildewcide agent in the form of a metered dose aerosol product.

4. An antifungal agent containing carveol, An antifungal agent in the form of a metered dose aerosol product (excluding cases where the amount of a single spray of a metered dose aerosol product is 1.0 to 3.0 mL and the duration of a single spray is 0.8 seconds or less).

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