Information processing device, information processing system, information processing method, and program

Abstract

To provide an information processing device capable of predicting timing when a symptom related to photosensitivity of a patient suffering from photosensitivity manifests itself.SOLUTION: An information processing device comprises a data acquisition section for acquiring a reference information set including at least one reference information selected from (a) to (l) in the following, and environment data, and an information generation section for generating provided information provided to a predetermined terminal on the basis of the environment data and the reference information set. (a): sunshine duration until a symptom related to photosensitivity manifests itself (b): timing of a symptom related to photosensitivity (c): grade of a symptom related to photosensitivity (d): PGIC score (e): skin coloring matter information (f): melanin density (g): an amount of protoporphyrin in blood (h): medicine type (i): an amount of prescription of medicine (j): Fitzpatrick skin typing (k): PGIS score (l): data obtained by PROMIS.SELECTED DRAWING: Figure 3

Description

[Technical Field]

[0001] The present invention relates to an information processing device, an information processing system, an information processing method, and a program. [Background technology]

[0002] Photosensitivity is a general term for skin diseases that are caused or worsened by exposure to sunlight or ultraviolet rays, and symptoms related to photosensitivity such as dermatitis can appear even with light exposure that would not cause a reaction in healthy people.

[0003] There are few fundamental treatments for photosensitivity, and the mainstream method for avoiding or alleviating the symptoms is to prevent the skin from being exposed to sunlight. For example, there is a technology for preventing the skin from being exposed to sunlight that notifies the user of weather information (for example, Patent Document 1, etc.). [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Japanese Patent Application Publication No. 2020-77197 Summary of the Invention [Problem to be solved by the invention]

[0005] Patients with photosensitivity tend to avoid going outside during the day for fear of developing photosensitivity-related symptoms, and there is a desire to improve their quality of life by knowing in advance when photosensitivity-related symptoms will develop.

[0006] An object of the present invention is to provide an information processing device that can predict the timing at which symptoms related to photosensitivity will appear in a patient suffering from photosensitivity. [Means for solving the problem]

[0007] The main invention of the present invention to solve the above problems is: an acquisition unit that acquires a reference information set including one or more pieces of reference information selected from the following (a) to (l) and environmental data; a generation unit that generates information to be provided to a predetermined terminal based on the environmental data and the reference information set; An information processing device comprising: (a) Duration of sun exposure before photosensitivity-related symptoms appear (b) Timing of photosensitivity-related symptoms (c) Grade of photosensitivity-related symptoms (d) Patient Global Impression of Change (PGIC) score (e) Skin pigment information (f) Melanin density (g) Amount of protoporphyrin in blood (h) Type of medication (i) Prescription amount of medication (j) Fitzpatrick skin type (k) PGIS score (Patient Global Impression Severity) (l) Data obtained through PROMIS (Patient-Reported Outcomes Measurement Information System)

[0008] Other problems and solutions disclosed in this application will be made clear in the section on preferred embodiments of the invention and the drawings. [Effects of the Invention]

[0009] According to the present invention, it is possible to provide an information processing device that can predict the timing at which symptoms related to photosensitivity will appear in a patient suffering from photosensitivity. [Brief explanation of the drawings]

[0010] [Figure 1] FIG. 1 is a diagram showing an example of the configuration of an information processing system including an information processing apparatus. [Figure 2] FIG. 1 is a diagram showing an example of the hardware configuration of an information processing apparatus. [Figure 3]FIG. 2 is a diagram showing an example of the software configuration of an information processing apparatus. [Figure 4] FIG. 4 is a diagram showing an example of the configuration of patient information stored in a patient information storage unit. [Figure 5] FIG. 3 is a diagram showing an example of the configuration of environmental data stored in an environmental data storage unit. [Figure 6] FIG. 4 is a diagram showing an example of the configuration of doctor-input information stored in a doctor-input information storage unit. [Figure 7] FIG. 4 is a diagram showing an example of the configuration of provided information stored in a provided information storage unit; [Figure 8] FIG. 2 is a diagram showing the flow of processing executed in the information processing device. DETAILED DESCRIPTION OF THE INVENTION

[0011] The present invention will be described by listing the contents of the embodiments. For example, the present invention has the following configuration.

[0012] [Item 1] an acquisition unit that acquires a reference information set including one or more pieces of reference information selected from the following (a) to (l) and environmental data; a generation unit that generates information to be provided to a predetermined terminal based on the environmental data and the reference information set; An information processing device comprising: (a) Duration of sun exposure before photosensitivity-related symptoms appear (b) Timing of photosensitivity-related symptoms (c) Grade of photosensitivity-related symptoms (d) Patient Global Impression of Change (PGIC) score (e) Skin pigment information (f) Melanin density (g) Amount of protoporphyrin in blood (h) Type of medication (i) Prescription amount of medication (j) Fitzpatrick skin type (k) PGIS score (Patient Global Impression Severity) (l) Data obtained through PROMIS (Patient-Reported Outcomes Measurement Information System) [Item 2] Item 2. The information processing device according to item 1, wherein the provided information is information encouraging shading. [Item 3] 3. The information processing device according to item 1 or 2, wherein the provided information is information regarding the expected sunshine duration until the onset of symptoms associated with photosensitivity calculated from the reference information set. [Item 4] It also has an information department, the generating unit generates information regarding the remaining time of the estimated sunshine duration; Item 4. The information processing device according to item 3, wherein the information providing unit notifies the terminal of the remaining estimated sunshine hours. [Item 5] 5. The information processing device according to any one of items 1 to 4, wherein the environmental data includes one or more selected from solar radiation data, sunlight wavelength data, and weather information. [Item 6] 6. The information processing device according to any one of items 1 to 5, wherein the one or more pieces of reference information selected from (a) to (l) are information acquired from a clinical trial information database. [Item 7] The information processing device according to claim 6 , wherein the reference information set further includes self-reported information of patients who require treatment for photosensitivity. [Item 8] 8. The information processing device according to item 7, wherein the self-reported information includes one or more selected from the following (Ia) to (Im): (Ia) Self-reported information of patients requiring treatment for phototoxic dermatitis (Ib) Self-reported information of patients requiring treatment for photoallergic dermatitis (Ic) Self-reported information from patients needing treatment for pellagra. (Id) Self-reported information of patients requiring treatment for porphyria (Ie) Self-reported information of patients requiring treatment for xeroderma pigmentosum (If) Self-reported information of patients requiring treatment for Cockayne's syndrome (Ig) Self-reported information of patients seeking treatment for Bloom syndrome (Ih) Self-reported information of patients seeking treatment for albinism (Ii) Self-reported information of patients requiring treatment for phenylketonuria (Ij) Self-reported information of patients requiring treatment for variola vaccinia (Ik) Self-reported information of patients requiring treatment for solar urticaria (Il) Self-reported information of patients requiring treatment for polymorphous light eruption (Im) Self-reported information of patients requiring treatment for chronic actinic dermatitis [Item 9] Item 9. The information processing device according to Item 8, wherein the (Id) self-reported information of a patient in need of treatment for porphyria includes one or more selected from the following (Ida) to (Idf): (Ida) Self-reported information of patients requiring treatment for erythropoietic protoporphyria (EPP) (Idb) Self-reported information from patients requiring treatment for X-linked porphyria (XLP) (Idc) Self-reported information of patients requiring treatment for congenital erythropoietic porphyria (CEP) (Idd) Self-reported information of patients requiring treatment for variegate porphyria (VP) (Ide) Self-reported information of patients requiring treatment for acute intermittent porphyria (AIP) (Idf) Self-reported information of patients requiring treatment for porphyria cutanea tarda (PCT) [Item 10] 10. The information processing device according to any one of items 7 to 9, wherein the self-reported information is acquired from a patient terminal of the patient. [Item 11] 11. The information processing device according to any one of items 7 to 10, wherein the reference information set is updated based on the self-reported information. [Item 12] 12. The information processing device according to any one of items 1 to 11, wherein the information providing unit provides the provided information to a terminal owned by the patient or a doctor terminal operable by a doctor. [Item 13] Item 13. The information processing device according to item 12, wherein the acquisition unit acquires input information from the doctor terminal. [Item 14] 14. The information processing device according to any one of items 1 to 13, wherein the acquisition unit acquires one or more data selected from (x) the amount of solar radiation, (y) the intensity distribution of the light spectrum, and (z) the time the patient spends outside. [Item 15] an acquisition unit that acquires a reference information set including one or more pieces of reference information selected from the following (a) to (l) and environmental data; a generation unit that generates information to be provided to a predetermined terminal based on the environmental data and the reference information set; An information processing system comprising: (a) Duration of sun exposure before photosensitivity-related symptoms appear (b) Timing of photosensitivity-related symptoms (c) Grade of photosensitivity-related symptoms (d) Patient Global Impression of Change (PGIC) score (e) Skin pigment information (f) Melanin density (g) Amount of protoporphyrin in blood (h) Type of medication (i) Prescription amount of medication (j) Fitzpatrick skin type (k) PGIS score (Patient Global Impression Severity) (l) Data obtained through PROMIS (Patient-Reported Outcomes Measurement Information System) [Item 16] An information processing method using a computer, comprising: A step of acquiring a reference information set including one or more pieces of reference information selected from the following (a) to (l) and environmental data; generating information to be provided to a predetermined terminal based on the environmental data and the reference information set; An information processing method comprising: (a) Duration of sun exposure before photosensitivity-related symptoms appear (b) Timing of photosensitivity-related symptoms (c) Grade of photosensitivity-related symptoms (d) Patient Global Impression of Change (PGIC) score (e) Skin pigment information (f) Melanin density (g) Amount of protoporphyrin in blood (h) Type of medication (i) Prescription amount of medication (j) Fitzpatrick skin type (k) PGIS score (Patient Global Impression Severity) (l) Data obtained through PROMIS (Patient-Reported Outcomes Measurement Information System) [Item 17] A program for causing a computer to execute an information processing method, The program is an information processing method, A step of acquiring a reference information set including one or more pieces of reference information selected from the following (a) to (l) and environmental data; generating information to be provided to a predetermined terminal based on the environmental data and the reference information set; A program that causes a computer to execute the following. (a) Duration of sun exposure before photosensitivity-related symptoms appear (b) Timing of photosensitivity-related symptoms (c) Grade of photosensitivity-related symptoms (d) Patient Global Impression of Change (PGIC) score (e) Skin pigment information (f) Melanin density (g) Amount of protoporphyrin in blood (h) Type of medication (i) Prescription amount of medication (j) Fitzpatrick skin type (k) PGIS score (Patient Global Impression Severity) (l) Data obtained through PROMIS (Patient-Reported Outcomes Measurement Information System)

[0013] <Details of the embodiment> A specific example of an information processing device 10 according to an embodiment of the present invention will be described with reference to the drawings.

[0014] In the present embodiment, as described in "New Dermatology, Third Edition, by Hiroshi Shimizu, Nakayama Shoten, 2018," "photosensitivity" is a synonym for "photosensitive dermatitis," and refers to a general term for skin diseases that occur or worsen due to exposure to sunlight or ultraviolet light. Therefore, in the present embodiment, photosensitivity can include all skin diseases that occur or worsen due to exposure to sunlight or ultraviolet light. Examples of photosensitivity include phototoxic dermatitis, photoallergic dermatitis, pellagra, porphyria, xeroderma pigmentosum, Cockayne's syndrome, Bloom's syndrome, albinism, phenylketonuria, variola vacciniformis, solar urticaria, polymorphous light eruption, and chronic actinic dermatitis.

[0015] Porphyria, a type of photosensitivity, is a disease caused by the accumulation of porphyrins or their precursors due to a decrease in the activity of heme metabolic enzymes. One of the symptoms is photosensitivity (sunburn, burn-like symptoms). Examples of porphyria include erythropoietic protoporphyria (EPP), X-linked protoporphyria (XLP), congenital erythropoietic porphyria (CEP), variegate porphyria (VP), acute intermittent porphyria (AIP), and porphyria cutanea tarda (PCT).

[0016] "Photosensitivity-related symptoms" refers to a condition that occurs or worsens in photosensitive patients due to exposure to sunlight or ultraviolet light, and after exposure to sunlight, prodromal symptoms (burning, stinging, itching, or tingling) change to pain. Therefore, in this embodiment, photosensitivity-related symptoms include both the prodromal symptoms and pain.

[0017] <Configuration> 1 is a diagram showing an example of an information processing system 1 including an information processing device 10 according to this embodiment. In this embodiment, the information processing device 10 is communicably connected to a patient terminal 20 owned by a patient and a doctor terminal 30 via a network NW.

[0018] In this embodiment, the network NW is, for example, the Internet, and is constructed using, for example, a public telephone network, a mobile phone network, a wireless communication network, Ethernet (registered trademark), or the like.

[0019] The information processing device 10 is a terminal managed by a medical institution or an organization that provides medical information, and constitutes part of the information provision system 1 by executing information processing with the patient terminal 20 and the doctor terminal 30 via a network NW. The information processing device 10 may be, for example, a workstation or a general-purpose computer such as a personal computer, or may be logically realized by cloud computing. An application or the like that enables communication with the patient terminal 20 and the doctor terminal 30 may be installed on the information processing device 10, and a browser for accessing a web service that enables such communication may be installed on the information processing device 10.

[0020] The patient terminal 20 executes information processing via the information processing device 10 and the doctor terminal 30 via a network NW. The information processing device 10 may be, for example, a general-purpose computer such as a workstation or a personal computer, or a mobile communication device such as a smartphone. The patient terminal 20 may also be a wearable device worn by the patient. Such a patient terminal 20 may have installed thereon an application or the like that enables communication with the information processing device 10 and the doctor terminal 30, or may have installed thereon a browser for accessing a web service that enables such communication.

[0021] The doctor terminal 30 is a terminal used by a doctor working at a medical institution such as a hospital to understand the condition of a patient, and executes information processing via the information processing device 10 and the patient terminal 20 and the network NW. The doctor terminal 30 may be, for example, a general-purpose computer such as a workstation or a personal computer, or may be a mobile communication device such as a smartphone. An application or the like that enables communication with the information processing device 10 or the patient terminal 20 may be installed on the doctor terminal 30, and a browser for accessing a web service that enables such communication may be installed on the doctor terminal 30.

[0022] <Hardware configuration> 2 is a diagram showing an example of the hardware configuration of a computer that realizes the information processing device 10 according to this embodiment. The computer includes at least a control unit 11, a memory 12, a storage 13, a communication unit 14, and an input / output unit 15. These are electrically connected to each other via a bus 16.

[0023] The control unit 11 is a computing device that controls the overall operation of the information processing device 10, controls the transmission and reception of data between each element, and performs information processing necessary for application execution and authentication processing. For example, the control unit 11 is a processor such as a CPU (Central Processing Unit), and executes programs stored in the storage 13 and deployed in the memory 12 to perform various information processing.

[0024] The memory 12 includes a main memory configured as a volatile storage device such as a DRAM (Dynamic Random Access Memory) and an auxiliary memory configured as a nonvolatile storage device such as a flash memory or an HDD (Hard Disc Drive). The memory 12 is used as a work area for the control unit 11, and also stores a BIOS (Basic Input / Output System) that is executed when the information processing device 10 is started up, various setting information, and the like.

[0025] The storage 13 stores various programs such as application programs. A database that stores data used for each process may be constructed in the storage 13.

[0026] The communication unit 14 connects the information processing device 10 to a network. The communication unit 14 communicates with external devices directly or via a network access point, for example, by a wired local area network (LAN), a wireless LAN, Wi-Fi (Wireless Fidelity, registered trademark), infrared communication, Bluetooth (registered trademark), short-range or contactless communication, or the like.

[0027] The input / output unit 15 is, for example, an information input device such as a keyboard, a mouse, or a touch panel, and an output device such as a display.

[0028] A bus 16 is commonly connected to the above elements and transmits, for example, address signals, data signals and various control signals.

[0029] In this embodiment, the hardware configuration of the terminals such as computers and smartphones that realize the patient terminal 20 and the doctor terminal 30 is the same as the example of the hardware configuration of the information processing device 10 shown in FIG. 2, and therefore a description thereof will be omitted.

[0030] <Software configuration> 3 is a diagram showing an example of the software configuration of the information processing device 10 according to this embodiment. The information processing device 10 can include functional units, namely, a data acquisition unit 101, an information generation unit 102, an information provision unit 103, a patient terminal notification unit 104, and a doctor terminal notification unit 105, as well as storage units, namely, a patient information storage unit 111, an environmental data storage unit 112, a doctor input information storage unit 113, and a provision information storage unit 114.

[0031] The data acquisition unit 101, the information generation unit 102, the information provision unit 103, the patient terminal notification unit 104, and the hospital terminal notification unit 105 are realized by the control unit 11 provided in the information processing device 10 reading out programs stored in the storage 13 into the memory 12 and executing the programs. The patient information storage unit 111, the environmental data storage unit 112, the doctor input information storage unit 113, and the provided information storage unit 114 are realized as part of a storage area provided by at least one of the memory 12 and the storage 13.

[0032] The patient information storage unit 111 stores patient information acquired by the data acquisition unit 101. The patient information storage unit 111 includes, for example, basic patient information and a patient reference information set. FIG. 4 shows an example of the configuration of patient information stored in the patient information storage unit 111. The patient information may be linked to a patient ID. The basic patient information may include information on attributes such as the patient's name, age, sex, address, occupation, and place of origin, as well as information on lifestyle habits such as chronic illnesses, medical history, allergies, constitution (obesity, frailty, etc.), diet, drinking, smoking, and exercise habits.

[0033] The patient reference information set stored in the patient information storage unit 111 includes, for example, one or more pieces of patient reference information selected from the following (a) to (l): (a) Duration of sun exposure before photosensitivity-related symptoms appear (b) Timing of photosensitivity-related symptoms (c) Grade of photosensitivity-related symptoms (d) Patient Global Impression of Change (PGIC) score (e) Skin pigment information (f) Melanin density (g) Amount of protoporphyrin in blood (h) Type of medication (i) Prescription amount of medication (j) Fitzpatrick skin type (k) PGIS score (Patient Global Impression Severity) (l) Data obtained through PROMIS (Patient-Reported Outcomes Measurement Information System)

[0034] These reference information sets may be, for example, information obtained from a clinical trial information database (not shown) that stores data (clinical trial data) obtained from clinical trials conducted at medical institutions, etc., or may be self-reported information from patients who require treatment for photosensitivity, such as erythropoietic protoporphyria (EPP) and / or X-linked porphyria (XLP).

[0035] When the reference information set is information acquired from a clinical trial information database, the reference information set may include the date on which the clinical trial was conducted and the date on which the data was acquired in addition to the above (a) to (l). The self-reported information may be information directly input into the patient terminal 20 by a patient using the patient terminal 20. The reference information set may also be information acquired from a database (not shown) that stores information input using the doctor terminal 30 by a doctor who has examined the patient. These reference information sets may be updated based on the self-reported information.

[0036] (a) "Sunlight duration until the onset of photosensitivity-related symptoms" refers to, for example, the duration of sunlight or ultraviolet exposure until the onset of photosensitivity-related symptoms in patients with photosensitivity in past clinical trials. For example, it refers to the time until the onset of photosensitivity-related symptoms in a clinical trial of Compound A in patients with erythropoietic protoporphyria and X-linked porphyria. That is, in a randomized double-blind clinical trial in which Compound A was administered to adult male and female patients with erythropoietic protoporphyria and X-linked porphyria for 16 weeks, it refers to the time until the first onset of symptoms caused by light exposure, including not only direct sunlight but also indirect sunlight, between one hour after sunrise and one hour before sunset.

[0037] Here, Compound A is, for example, a cocrystal containing 1-{2-[(3S,4R)-1-{[(3R,4R)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)pyrrolidin-3-yl]carbonyl}-4-(methoxymethyl)pyrrolidin-3-yl]-5-(trifluoromethyl)phenyl}piperidine-4-carboxylic acid and phosphoric acid.

[0038] (b) "Timing of photosensitivity-related events" refers to the number of photosensitivity-related events recorded by a patient with photosensitivity. For example, it refers to the number of photosensitivity-related events recorded by a patient during a 16-week evaluation period in a clinical trial of Compound A in patients with erythropoietic protoporphyria and X-linked porphyria.

[0039] (c) "Grade of photosensitivity-related symptoms" is a graded evaluation of the intensity (degree) and pattern of photosensitivity-related symptoms recorded by patients with photosensitivity, using numbers, etc. For example, pain is categorized into 11 levels from 0 to 10, with 0 being no pain and 10 being the worst pain imaginable, and patients are asked to rate their pain.

[0040] (d) "PGIC (Patient Global Impression of Change) score" means a patient's health-related quality of life. For example, it is an evaluation of a patient's health-related quality of life in a clinical trial of Compound A targeting patients with erythropoietic protoporphyria and X-linked porphyria, and is the degree of improvement in overall physical and mental health recorded by the patient at 16 weeks of the clinical trial. For example, it is a questionnaire in which the degree of improvement is scored on a 7-point scale, with the lowest score of 7 indicating "marked worsening" and the highest score of 1 indicating "marked improvement."

[0041] (e) "Skin pigmentation information" means skin pigmentation information of a patient with photosensitivity.

[0042] (f) "Melanin density" means the melanin density of the skin of a photosensitive patient, for example, the melanin density measured using a spectrophotometer at six locations on the skin of the patient at the 16-week point of the clinical trial: the forehead, left cheek, right inner upper arm, left inner outer arm, right side of the abdomen, and left side of the buttocks.

[0043] (g) "Protoporphyrin level in blood" refers to the protoporphyrin level in the blood of a patient with photosensitivity, for example, the protoporphyrin level in the blood of a patient with photosensitivity at 16 weeks after the clinical trial.

[0044] (h) "Type of medication" means the type of medication administered to a patient with photosensitivity, for example, the type of medication administered in the clinical trial.

[0045] (i) "Prescribed amount of drug" means the prescribed amount of drug administered to a patient with photosensitivity. For example, it means the prescribed amount of drug administered in the clinical trial. Here, the period of drug administration may also be included.

[0046] (j) "Fitzpatrick skin type" is a scale that classifies human skin color into six levels (Type 1 to Type 6) based on sensitivity to UV exposure. In particular, it is a scale that classifies skin types based on the occurrence of "red sunburn," which is a burn caused by UV exposure, and "black sunburn," which occurs as a reaction to UV radiation by synthesizing melanin in the skin to protect the body from UV rays. For example, it refers to the skin type in the above clinical trial.

[0047] (k) "PGIS score (Patient Global Impression Severity)" means a comprehensive score that may be used to evaluate the severity of a disease according to the patient's impression. For example, in clinical trials, the comprehensive score is used to evaluate the severity of a disease as assigned by the subject. The subject evaluates their own perceived severity on a five-point scale ranging from "none" to "very severe."

[0048] (l) "Data obtained from the Patient-Reported Outcomes Measurement Information System (PROMIS)" refers to data obtained from indicators assessing seven domains: physical function, anxiety, depression, fatigue, sleep disturbance, ability to participate in social roles and activities, and pain interference (including pain intensity). For example, this refers to the change in PROMIS score (total score and total score of each domain) in the above clinical trial.

[0049] Items (a) through (l) above may be updated based on self-reported information.

[0050] The self-reported information includes, for example, one or more items selected from the following (Ia) to (Im): (Ia) Self-reported information of patients requiring treatment for phototoxic dermatitis (Ib) Self-reported information of patients requiring treatment for photoallergic dermatitis (Ic) Self-reported information from patients needing treatment for pellagra. (Id) Self-reported information of patients requiring treatment for porphyria (Ie) Self-reported information of patients requiring treatment for xeroderma pigmentosum (If) Self-reported information of patients requiring treatment for Cockayne's syndrome (Ig) Self-reported information of patients seeking treatment for Bloom syndrome (Ih) Self-reported information of patients seeking treatment for albinism (Ii) Self-reported information of patients requiring treatment for phenylketonuria (Ij) Self-reported information of patients requiring treatment for variola vaccinia (Ik) Self-reported information of patients requiring treatment for solar urticaria (Il) Self-reported information of patients requiring treatment for polymorphous light eruption (Im) Self-reported information of patients requiring treatment for chronic actinic dermatitis

[0051] The above (Id) self-reported information of patients in need of treatment for porphyria includes, for example, one or more selected from the following (Ida) to (Idf): (Ida) Self-reported information of patients requiring treatment for erythropoietic protoporphyria (EPP) (Idb) Self-reported information from patients requiring treatment for X-linked porphyria (XLP) (Idc) Self-reported information of patients requiring treatment for congenital erythropoietic porphyria (CEP) (Idd) Self-reported information of patients requiring treatment for variegate porphyria (VP) (Ide) Self-reported information of patients requiring treatment for acute intermittent porphyria (AIP) (Idf) Self-reported information of patients requiring treatment for porphyria cutanea tarda (PCT)

[0052] The self-reported information may be updated each time the self-reported information is obtained.

[0053] The patient's reference information set stored in the patient information storage unit 111 may include information on medications other than those for photosensitivity, commonly used medications, etc., and in that case, the prescribed amounts may also be included. In addition, it may also include images of the skin taken using a camera or the like.

[0054] The environmental data storage unit 112 stores data related to the environment acquired by the data acquisition unit 101. FIG. 5 shows an example of the configuration of environmental data stored in the environmental data storage unit 112. The environmental data may include, for example, solar radiation data such as ultraviolet light amounts, sunlight wavelength data, and weather information, as well as temperature, humidity, wind speed, and the like. This information may be data automatically or manually acquired from a solar radiation measurement app or a sunlight measurement app installed in the information processing device 10, or data entered by the patient into the patient terminal 20. If the patient terminal 20 is a wearable device terminal, the environmental data may be data directly acquired by the wearable device terminal. Alternatively, the environmental data may be data automatically acquired by the wearable device terminal. Alternatively, the environmental data may be data automatically acquired by automatically acquiring weather information for the region published by the Japan Meteorological Agency or the like. In other words, the information processing device 10 may automatically acquire and store information in cooperation with publicly known information.

[0055] The doctor input information storage unit 113 stores the doctor input information acquired from the doctor terminal 30. Fig. 6 shows an example of the configuration of the doctor input information stored in the doctor input information storage unit 113. The doctor input information includes, for example, patient consultation information, that is, the patient consultation date and time, and information similar to (a) to (l) included in the above-mentioned reference information set.

[0056] The provided information storage unit 114 stores provided information generated based on the reference information set stored in the patient information storage unit 111 and the environmental data stored in the environmental data storage unit 112. Fig. 7 shows an example of the configuration of provided information stored in the provided information storage unit 114. The provided information may include, for example, information encouraging protection from light, the estimated sunshine hours until the onset of photosensitivity-related symptoms calculated from the reference information set, and the remaining time until the onset of photosensitivity-related symptoms.

[0057] The data acquisition unit 101 acquires a reference information set including one or more pieces of reference information selected from (a) to (l) and environmental data. The data acquisition unit 101 may acquire the reference information set including the above-mentioned reference information and the environmental data from the patient terminal 20 or the doctor terminal 30, or via another data server. Alternatively, the data acquisition unit 101 may acquire, for example, information on the amount of solar radiation or the intensity distribution of the light spectrum, or information on the patient's time outside, from an app installed on the information processing device 10. The data acquisition unit 101 may also accept data related to the patient's own reference information and environmental data, for example, input by the patient himself or herself, or input data from a person other than the patient, such as the patient's family or friends, or may accept input data from two or more people. The information acquired by the data acquisition unit 101 is stored in the patient information storage unit 111, the environmental data storage unit 112, or the doctor-input information storage unit 113.

[0058] The information generation unit 102 generates information to be provided to a predetermined terminal based on the data acquired by the data acquisition unit 101. That is, the information to be provided to the patient or doctor is generated based on the patient's reference information set including one or more pieces of reference information selected from (a) to (l) and environmental data. As described above, the information to be provided to the patient may include, for example, information encouraging protection from light, the estimated sunshine hours until the onset of symptoms related to photosensitivity calculated from the reference information set, and the estimated remaining sunshine hours. The generated information is transmitted to the patient terminal 20 or the doctor terminal 30 by the information provision unit 103. The information generated by the information generation unit 102 is stored in the provided information storage unit 114.

[0059] The information providing unit 103 provides the provided information generated by the information generating unit 102 to a predetermined terminal. The terminal to which the information providing unit 103 provides information may be the patient terminal 20 owned by the patient, the doctor terminal 30, or any other terminal of a third party.

[0060] The patient terminal notification unit 104 notifies the patient of a message prompting the patient to acquire reference information and environmental data, for example, at a preset timing. The timing may be set for each patient, and intervals or time periods may be set, such as notifying at a predetermined time every day or once a week. Furthermore, a warning may be issued based on the information provided by the information providing unit 103. For example, a warning indicating a high possibility of the onset of photosensitivity-related symptoms may be issued when the remaining expected daylight hours are running low, for example, when the remaining time is less than one hour.

[0061] For example, when the provided information of the patient is acquired from the information providing unit 103 at a preset timing, the doctor terminal notifying unit 105 notifies a message prompting confirmation of the provided information. Also, for example, when an appointment for a medical examination is input from the patient terminal 20 and the appointment information is acquired via the information processing device 10, the doctor terminal notifying unit 105 may notify the appointment information.

[0062] <Information processing flow> FIG. 8 is a diagram showing the flow of processing executed in the information processing device 10 according to the first embodiment.

[0063] First, as preprocessing for this process, the data acquisition unit 101 of the information processing device 10 accepts input of information about the patient and stores the patient basic information in the patient information storage unit 111. If patient information has already been stored in the patient information storage unit 111, it is also possible to refer to the patient information required for the information processing according to this embodiment by accepting input of a patient ID, etc.

[0064] Next, the data acquisition unit 101 acquires a reference information set including one or more pieces of reference information selected from the above (a) to (l) and environmental data (S101). These data may be acquired from data held by the patient terminal 20, the doctor terminal 30, or another server, or may be acquired automatically by the information processing device 10 in conjunction with publicly known information, or may be acquired by an installed app. For example, when solar radiation data or sunlight wavelength data is to be acquired, the corresponding app is started to acquire the data.

[0065] The information generation unit 102 generates information to be provided to a predetermined terminal based on the data acquired by the data acquisition unit 101 (S102). That is, the information to be provided to the patient, doctor, etc. is generated based on the patient's reference information set including one or more pieces of reference information selected from (a) to (l) and the environmental data.

[0066] The information providing unit 103 provides the information generated by the information generating unit 102 to a predetermined terminal (S103). The terminal to which the information providing unit 103 provides information may be the patient terminal 20 owned by the patient, the doctor terminal 30, or any other terminal of a third party. The information provided to the patient terminal 20 may include, for example, information encouraging protection from light, the estimated sunshine hours until symptoms related to photosensitivity appear, and the remaining time until symptoms related to photosensitivity appear.

[0067] In this way, the information processing device 10 of this embodiment predicts the timing at which photosensitivity-related symptoms will appear in a photosensitivity patient and provides the result to a predetermined terminal. As a result, the photosensitivity patient can know the timing at which photosensitivity-related symptoms will appear by checking the provided information provided to the patient terminal 20, and can take measures to prevent the appearance of photosensitivity-related symptoms by blocking out light or changing the time they go outside. Furthermore, if there is time remaining until the appearance of photosensitivity-related symptoms, they can go outside without blocking out light.

[0068] Therefore, according to the information processing device 10 of this embodiment, by knowing in advance the timing at which photosensitivity-related symptoms will appear, patients with photosensitivity can adjust their outside time without needlessly avoiding going outside during the day for fear of the appearance of photosensitivity-related symptoms, thereby improving their quality of life.

[0069] Although the present embodiment has been described above, the above embodiment is intended to facilitate understanding of the present invention and is not intended to limit the present invention. The present invention may be modified or improved without departing from the spirit thereof, and equivalents thereof are also included in the present invention.

[0070] For example, in this embodiment, for convenience of explanation, one information processing device 10, one patient terminal 20, and one doctor terminal 30 are illustrated, but multiple patient terminals 20 and multiple doctor terminals 30 can be connected to the information processing device 10 via a network NW. Also, while the information processing device 10 is illustrated as a single computer, this is not limiting, and a system may be configured in which functional units and storage units are distributed across multiple computers. For example, each storage unit of the information processing device 10 may be provided in a database server, and the information processing device 10 may access the database server. Also, each functional unit may be distributed across multiple computers.

[0071] The information processing device 10 may be a patient terminal owned by the patient, and may be configured to access a separately provided database server.

[0072] Furthermore, the system may include configurations other than the functional units and components included in FIG. 3. Also, other steps may be added to each of the steps included in FIG. 8. For example, in S101, when an image of a patient's skin is captured by a camera (not shown), an image capture application may be launched to acquire the skin image. Also, in S101, the reference information set may be updated based on self-reported information. This makes it possible to more accurately predict the timing at which photosensitivity-related symptoms will appear in a patient with photosensitivity.

[0073] Also, in S103 or after S103, a warning may be issued to the patient terminal 20 based on the provided information. Furthermore, an evaluation unit may be provided that evaluates the efficacy of a drug in a clinical trial based on the provided information, and the result may be notified to the doctor terminal 30. Also, based on the evaluation, the system may be set to encourage the patient to visit the doctor. In that case, the system may accept an appointment for a consultation and notify the doctor terminal 30.

[0074] Although the preferred embodiments of the present disclosure have been described in detail above with reference to the accompanying drawings, the technical scope of the present disclosure is not limited to such examples. It is clear that a person skilled in the art of the present disclosure can conceive of various modified or altered examples within the scope of the technical idea described in the claims, and it is understood that these also naturally fall within the technical scope of the present disclosure.

[0075] Furthermore, the effects described herein are merely descriptive or exemplary and are not limiting. In other words, the technology according to the present disclosure may achieve other effects that will be apparent to those skilled in the art from the description of this specification, in addition to or in place of the above-described effects. [Explanation of symbols]

[0076] 1. Information Processing Systems 10. Information processing equipment 11 Control section 12 Memory 13. Storage 14 Communications Department 15 Incoming and outgoing 16 Bus 20 Patient terminal 30 Doctor's terminal 101 Data Acquisition Unit 102 Information generation section 103 Information Provision Department 104 Patient terminal notification unit 105 Doctor terminal notification unit 111 Patient information storage unit 112 Environmental data storage unit 113 Physician input information storage unit 114 Provided information storage unit NW Network

Claims

[Claim 1] An information processing device as described in the specification or drawings.

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