Composition for external use on skin for reducing skin wrinkles containing polyvinyl alcohol

Abstract

To provide a composition for external use on the skin for reducing skin wrinkles containing polyvinyl alcohol, and more particularly, a composition excellent in reducing skin wrinkles by sustainably contracting the skin only by drying after application to the skin without a separate film, by containing a high molecular weight polyvinyl alcohol.SOLUTION: The composition according to the present disclosure can reduce skin wrinkles without side effects and at a lower cost compared to conventional wrinkle-improving treatments.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] This specification relates to an external skin preparation composition containing polyvinyl alcohol for reducing skin wrinkles, and discloses an external skin preparation composition that contains high molecular weight polyvinyl alcohol and thereby can contract the skin and reduce wrinkles. [Background technology]

[0002] Skin wrinkles are the most noticeable external feature of skin aging, caused by internal factors such as aging and stress, or external environmental factors such as air pollution and UV exposure. Wrinkles appear on various parts of the body, including the face (forehead, around the eyes, between the eyebrows, and around the mouth), the neck, neckline, elbows, armpits, hands, and feet. They usually become noticeable around the age of 30, and their number, depth, and extent increase with age. The primary cause of these wrinkles is reactive oxygen species generated in skin tissue during the skin aging process, which ultimately form crosslinks between collagen and elastic fibers, which make up the majority of the skin's dermis, altering the production and degradation of these fibers.

[0003] Currently, substances used to improve skin wrinkles include antioxidants and radical scavengers such as vitamin E, beta-carotene, vitamin C, and glutathione, which are used to inhibit skin aging, as well as substances that promote dermal collagen synthesis, such as vitamin A. However, many of the active ingredients in these cosmetics have drawbacks, such as being highly irritating to the skin or being unstable in the formulation, causing discoloration, odor, and precipitation, or reducing the activity of the original ingredients.

[0004] On the other hand, polyvinyl alcohol is widely known as a film-forming agent, but low molecular weight polyvinyl alcohol is mainly used, and even when mixed with high molecular weight polyvinyl alcohol, it is only used in pack-type cosmetics that form a film, or in film formation to form a moisturizing film, so it is difficult to continuously provide the wrinkle-improving effect. Furthermore, since the main purpose of conventional film-forming agents is to thin the film thickness, they are insufficient to provide the effect of tightening the skin and improving wrinkles. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] International Publication No. 2021 / 172430 Summary of the Invention [Problem to be solved by the invention]

[0006] One aspect of the present disclosure aims to provide a composition that, when applied to the skin, can continuously contract the skin and reduce wrinkles on the skin. [Means for solving the problem]

[0007] In one aspect, the present disclosure provides a skin topical preparation composition for reducing skin wrinkles, comprising polyvinyl alcohol having a number average molecular weight of 30,000 or more and a water-soluble thickener. [Effects of the Invention]

[0008] In one embodiment, the composition according to the present disclosure contains a high molecular weight polyvinyl alcohol, which can continuously contract the skin and reduce wrinkles on the skin.

[0009] In another aspect, when the composition according to the present disclosure is applied to the skin, the tension on the skin is in a range appropriate for improving wrinkles, thereby reducing wrinkles on the skin. [Brief explanation of the drawings]

[0010] [Figure 1] 1 is a photograph showing the effect of a composition according to an example of the present disclosure on reducing skin wrinkles (laugh lines). [Figure 2] 1 is a photograph showing the effect of a composition according to an example of the present disclosure on reducing skin wrinkles (laugh lines). [Figure 3] 1 is a photograph showing the effect of a composition according to an example of the present disclosure on reducing skin wrinkles (neck wrinkles). [Figure 4] 1 is a photograph showing the effect of a composition according to an example of the present disclosure on reducing skin wrinkles (neck wrinkles). DETAILED DESCRIPTION OF THE INVENTION

[0011] The present disclosure will be described in more detail below with reference to the following examples. However, the following examples are merely illustrative examples to aid in understanding the present disclosure, and are not intended to limit the scope of the present disclosure.

[0012] In an exemplary embodiment of the present disclosure, there is provided an external skin preparation composition for reducing skin wrinkles, comprising polyvinyl alcohol having a number average molecular weight of 30,000 or more and a water-soluble thickener.

[0013] In another exemplary implementation of the present disclosure, there is provided a method for reducing wrinkles on skin, comprising applying to the skin a composition comprising polyvinyl alcohol having a number average molecular weight of 30,000 or more and a water-soluble thickener.

[0014] In another exemplary embodiment of the present disclosure, there is provided a use of a composition comprising polyvinyl alcohol having a number average molecular weight of 30,000 or more and a water-soluble thickener for preparing a composition for reducing skin wrinkles.

[0015] In another exemplary embodiment of the present disclosure, there is provided a non-therapeutic use of a composition comprising polyvinyl alcohol having a number average molecular weight of 30,000 or more and a water-soluble thickener for reducing skin wrinkles.

[0016] In another exemplary embodiment of the present disclosure, there is provided a composition for reducing skin wrinkles, the composition comprising polyvinyl alcohol having a number average molecular weight of 30,000 or more and a water-soluble thickener.

[0017] According to the present disclosure, in order to form a film that has the effect of continuously shrinking wrinkles on the skin, a mixture of high molecular weight polyvinyl alcohol having a number average molecular weight of 30,000 or more and a water-soluble thickener is included so that the tensile force on the skin is suitable for reducing wrinkles.

[0018] In one embodiment, the topical skin composition for reducing skin wrinkles may be applied to a subject with reduced skin elasticity.

[0019] In one embodiment, the topical skin composition for reducing skin wrinkles may be applied to subjects with wrinkles on the face, such as the forehead, around the eyes, between the eyebrows, and around the mouth (laugh lines), or on the neck, neckline, elbows, armpits, hands, or feet.

[0020] In one embodiment, the topical skin composition is a general term that may include anything that is applied to the outer skin, and may include cosmetic compositions of various formulations.

[0021] In one implementation, the composition may be applied to the skin and then allowed to dry to shrink the skin.

[0022] In one embodiment, the number average molecular weight of the polyvinyl alcohol may be 200,000 or less.

[0023] For example, the number average molecular weight of the polyvinyl alcohol is 30,000 or more, 40,000 or more, 50,000 or more, 60,000 or more, 70,000 or more, 80,000 or more, 90,000 or more, 100,000 or more, 110,000 or more, 120,000 or more, 130,000 or more, 140,000 or more, 150,000 or more, 160,000 or more, 170,000 or more, 180,000 or more, or 190,000 or more. 00 or more, or may be 200,000 or less, 190,000 or less, 180,000 or less, 170,000 or less, 160,000 or less, 150,000 or less, 140,000 or less, 130,000 or less, 120,000 or less, 110,000 or less, 100,000 or less, 90,000 or less, 80,000 or less, 70,000 or less, 60,000 or less, 50,000 or less, or 40,000 or less.

[0024] In one implementation, the water-soluble thickener may include at least one selected from the group consisting of natural gums, cellulose, starch-derived thickeners, acrylate-based polymers, PEG-based polymers, and PPG-based polymers.

[0025] In one embodiment, the water-soluble thickener is selected from the group consisting of carrageenan, xanthan gum, cassia gum, gellan gum, carob bean gum, agar, algin, guar gum, pectin, glucomannan, cellulose gum, tamarind seed gum, microcrystalline cellulose, carboxymethyl cellulose, hydroxyethyl cellulose, corn starch, rice starch, sodium acrylate starch, hydrogenated starch, carbomer, polyacrylic acid, ammonium acryloyldimethyl taurate / VP copolymer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, and the like. The composition may include at least one selected from the group consisting of Acrylate / Sodium Acryloyldimethyl Taurate Copolymer, Polyacrylate-13, Acrylates / C10-30 Alkyl Acrylate Crosspolymer, PPG-17 / IPDI / DMPA Copolymer, Acrylates / Beheneth 25 Methacrylate Copolymer, and PEG 240 / HDI copolymer Bis decyltetradeceth 20 ether.

[0026] In one embodiment, the polyvinyl alcohol may be contained in an amount of 1 to 20% by weight based on the total weight of the composition.

[0027] For example, the polyvinyl alcohol may be contained in an amount of 1 wt % or more, 3 wt % or more, 5 wt % or more, 7 wt % or more, 9 wt % or more, 11 wt % or more, 13 wt % or more, 15 wt % or more, 17 wt % or less, or 19 wt % or more, relative to the total weight of the composition, and may be contained in an amount of 20 wt % or less, 18 wt % or less, 16 wt % or less, 14 wt % or less, 12 wt % or less, 10 wt % or less, 8 wt % or less, 6 wt % or less, 4 wt % or less, or 2 wt % or less.

[0028] In one embodiment, the water-soluble thickener may be contained in an amount of 0.1 to 5% by weight based on the total weight of the composition.

[0029] For example, the water-soluble thickener may be contained in an amount of 0.1 wt % or more, 0.5 wt % or more, 1 wt % or more, 1.5 wt % or more, 2 wt % or more, 2.5 wt % or more, 3 wt % or more, 3.5 wt % or more, 4 wt % or more, or 4.5 wt % or more, relative to the total weight of the composition, or 5 wt % or less, 4.5 wt % or less, 4 wt % or less, 3.5 wt % or less, 3 wt % or less, 2.5 wt % or less, 2 wt % or less, 1.5 wt % or less, 1 wt % or less, or 0.5 wt % or less.

[0030] In one embodiment, the weight ratio of the polyvinyl alcohol to the water-soluble thickener may be 1:0.01-0.6.

[0031] For example, the weight ratio of the polyvinyl alcohol to the water-soluble thickener may be 1:0.01 or more, 1:0.05 or more, 1:0.1 or more, 1:0.15 or more, 1:0.2 or more, 1:0.25 or more, 1:0.3 or more, 1:0.35 or more, 1:0.4 or more, 1:0.45 or more, 1:0.5 or more, or 1:0.55 or more, and may be 1:0.6 or less, 1:0.55 or less, 1:0.5 or less, 1:0.45 or less, 1:0.4 or less, 1:0.35 or less, 1:0.3 or less, 1:0.25 or less, 1:0.2 or less, 1:0.15 or less, 1:0.1 or less, or 1:0.05 or less.

[0032] If the weight ratio is too low, the film contraction force will decrease, and if the weight ratio is too high, a gel with high hardness will be formed, which may decrease the ease of application and spreadability on the skin.

[0033] In one implementation, the composition may be applied to the skin at a thickness of 0.1 to 2 mm.

[0034] For example, the thickness may be 0.1 mm or more, 0.3 mm or more, 0.5 mm or more, 0.7 mm or more, 0.9 mm or more, 1.1 mm or more, 1.3 mm or more, 1.5 mm or more, 1.7 mm or more, or 1.9 mm or more, or may be 2 mm or less, 1.8 mm or less, 1.6 mm or less, 1.4 mm or less, 1.2 mm or less, 1 mm or less, 0.8 mm or less, 0.6 mm or less, 0.4 mm or less, or 0.2 mm or less.

[0035] The contractile force may differ depending on the thickness or the amount applied; for example, if the amount applied is too small and the thickness is thin, the film-forming ability may decrease and the contractile force may decrease; if the amount applied is too large and the thickness is thick, the spreadability on the skin may decrease and the application may not be uniform, and the contractile force may not be exerted uniformly over the entire skin to which the composition is applied, which may decrease the wrinkle-improving ability.

[0036] In one embodiment, the thickness of the composition after drying may be 10 to 25% of the thickness of the composition immediately after application to the skin.

[0037] For example, the thickness of the composition after drying may be 10% or more, 12% or more, 14% or more, 16% or more, 18% or more, 20% or more, 22% or more, or 24% or more, and may be 25% or less, 23% or less, 21% or less, 19% or less, 17% or less, 15% or less, 13% or less, or 11% or less, relative to the thickness of the composition immediately after application to the skin.

[0038] In one implementation, the composition may contract the skin for at least one hour.

[0039] In one implementation, the composition may dry to a moisture content of 3% or less within 15 minutes of application to the skin.

[0040] In one embodiment, the composition may be used for 15 minutes to 24 hours.

[0041] For example, the usage time of the composition is the sum of the time required for the composition to dry and the time required for the skin to contract, and may be 15 minutes or more, 30 minutes or more, 1 hour or more, 2 hours or more, 3 hours or more, 4 hours or more, 5 hours or more, 6 hours or more, 7 hours or more, 8 hours or more, 9 hours or more, 10 hours or more, 11 hours or more, 12 hours or more, 13 hours or more, 14 hours or more, 15 hours or more, 16 hours or more, 17 hours or more, 18 hours or more, 19 hours or more, 20 hours or more, or 21 hours or more. , 22 hours or more, or 23 hours or more, or may be 24 hours or less, 23 hours or less, 22 hours or less, 21 hours or less, 20 hours or less, 19 hours or less, 18 hours or less, 17 hours or less, 16 hours or less, 15 hours or less, 14 hours or less, 13 hours or less, 12 hours or less, 11 hours or less, 10 hours or less, 9 hours or less, 8 hours or less, 7 hours or less, 6 hours or less, 5 hours or less, 4 hours or less, 3 hours or less, 2 hours or less, 1 hour or less, or 30 minutes or less.

[0042] In one implementation, the composition may be a cosmetic composition.

[0043] The cosmetic composition may comprise a cosmetically or dermatologically acceptable vehicle or base. This may be any formulation suitable for topical application, such as a solution, gel, solid, anhydrous product, emulsion obtained by dispersing an oily phase in an aqueous phase, suspension, microemulsion, microcapsule, microgranule, or ionic (liposomal) and non-ionic vesicular dispersion, or in the form of a cream, lotion, emulsion, powder, ointment, spray, or stick concealer. These compositions may be prepared according to conventional methods in the art. The compositions according to the present disclosure may also be used in the form of foam or in the form of an aerosol composition further comprising a compressed propellant.

[0044] The cosmetic composition according to one embodiment of the present disclosure is not particularly limited in its formulation, and may be formulated into cosmetics such as, for example, a softening lotion, an astringent lotion, a nourishing lotion, a nourishing cream, a massage cream, a serum, an eye cream, an eye essence, a cleansing cream, a cleansing foam, a cleansing water, a face mask, a powder, a body lotion, a body cream, a body oil, or a body essence.

[0045] When the cosmetic composition of the present disclosure is formulated as a paste, cream, or gel, animal fibers, plant fibers, wax, paraffin, starch, tragacanth, cellulose derivatives, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide, or the like may be used as a carrier component.

[0046] When the cosmetic composition of the present disclosure is formulated as a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder may be used as a carrier component, and particularly in the case of a spray, a propellant such as hydrochlorofluorocarbon, propane / butane, or dimethyl ether may be further included.

[0047] When the cosmetic composition of the present disclosure is formulated as a solution or emulsion, a solvent, solvating agent, or emulsifier is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3-butyl glycol oil, glycerin fatty acid esters, polyethylene glycol, and fatty acid esters of sorbitan.

[0048] When the formulation of the cosmetic composition of the present disclosure is a suspension, the carrier component may be a liquid diluent such as water, ethanol, or propylene glycol; a suspending agent such as ethoxylated stearyl alcohol, polyoxyethylene sorbitol ester, or polyoxyethylene sorbitan ester; or microcrystalline cellulose, aluminum metahydroxide, bentonite, agar, or tragacanth.

[0049] When the formulation of the cosmetic composition of the present disclosure is a surfactant-containing cleanser, the carrier component may include fatty alcohol sulfates, fatty alcohol ether sulfates, sulfosuccinate monoesters, isethionates, imidazolium derivatives, methyl taurates, sarcosinates, fatty acid amide ether sulfates, alkylamidobetaines, fatty alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives, and ethoxylated glycerin fatty acid esters.

[0050] In addition to the active ingredient, the cosmetic composition of the present disclosure may further include functional additives and ingredients commonly found in cosmetic compositions. The functional additives may include ingredients selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, polymeric peptides, polymeric polysaccharides, sphingolipids, and seaweed extracts.

[0051] The cosmetic composition of the present disclosure may further contain, as necessary, ingredients contained in general cosmetic compositions in addition to the functional additives, such as oils and fats, moisturizers, emollients, surfactants, organic and inorganic pigments, organic powders, UV absorbers, preservatives, disinfectants, antioxidants, plant extracts, pH adjusters, alcohols, colorants, fragrances, blood circulation enhancers, cooling agents, antiperspirants, purified water, etc.

[0052] The present disclosure will be described in more detail below with reference to the following examples. However, the following examples are merely illustrative examples to aid in understanding the present disclosure, and are not intended to limit the scope of the present disclosure.

[0053] [Example] Preparation of a composition for reducing skin wrinkles As shown in Tables 1 and 2 below, compositions containing PVA of different molecular weights, water, polyvinyl alcohol, and carbomer were prepared, and then coated on a PET film and dried, and the bending angle (shrinkage force) of the film was measured. Compositions Nos. 7 and 10 were marked x because they were too viscous and could not be prepared.

[0054] [Table 1]

[0055] [Table 2]

[0056] [Test example] Test Example 1 - Tensile Force The composition prepared in the examples was placed in a 46.75 cm 2 Approximately 2.7 g of the composition was applied to a transparent PET film (8.5 × 5.5 cm). That is, 0.06 g / cm 2 The solution was applied to a transparent PET film at a concentration of 1000 ppm (approximately 0.1 to 2 mm thick). After drying, the film was measured for its bending angle.

[0057] As a result of the observation, in the case of composition No. 3 containing the high molecular weight PVA (molecular weight up to 123,000) (8.5% by weight) of the example, the bending degree at room temperature was approximately 22 degrees, and in the case of composition No. 1 containing the low molecular weight PVA205 (molecular weight up to 25,000) (8.5% by weight) of the comparative example, the bending degree was approximately 15.5 degrees (see Tables 1 and 2).

[0058] Furthermore, in the case of composition No. 2 containing the medium molecular weight PVA217 (molecular weight: about 83,000), the degree of bending was confirmed to be about 18 degrees (see Tables 1 and 2).

[0059] Test Example 2 - Sustained effect of contractile force After the experiment in Test Example 1, the sample was stored in a refrigerator (4°C) for 24 hours, and it was confirmed how much contractile force was maintained even after 24 hours.

[0060] As a result of the observation, it was confirmed that in the case of composition No. 3 containing the high molecular weight PVA (molecular weight: 123,000) (8.5% by weight) of the example, the bending degree decreased from approximately 22 degrees to approximately 14 degrees, and that when low molecular weight PVA was used, there was little or only weak contraction force.

[0061] Furthermore, in the case of composition No. 2 containing the medium molecular weight PVA217 (molecular weight: up to 83,000), the degree of bending was approximately 5.5 degrees, and it was therefore determined that the composition could be attached to the skin.

[0062] Therefore, it was confirmed that optimal contraction force (wrinkle reduction) and ease of preparation can be achieved by using PVA with an appropriate level of molecular weight.

[0063] Test Example 3 - Wrinkle improvement effect on skin Composition No. 3 prepared in the example was applied to 46.75 cm of the skin of a man or woman in their 40s. 2 Approximately 2.7 g of the composition was applied to an area of ​​8.5 × 5.5 cm. That is, 0.06 g / cm 2 It was applied to the skin (nasolabial folds around the mouth and wrinkles on the neck) at a concentration of

[0064] The composition was applied for 1 hour and then removed, and the effect of improving nasolabial folds and neck wrinkles was then measured. Referring to Figures 1 and 2 for nasolabial folds, it can be seen that deep nasolabial folds were visibly reduced, and referring to Figures 3 and 4 for neck wrinkles, it can be seen that the number of neck wrinkles was reduced.

Claims

1. Polyvinyl alcohol having a number average molecular weight of 30,000 or more; A skin external preparation composition for reducing skin wrinkles, comprising:

2. The composition according to claim 1, which is intended to shrink the skin by applying the composition to the skin and then drying it.

3. The composition according to claim 1, wherein the number average molecular weight of the polyvinyl alcohol is 200,000 or less.

4. 10. The composition of claim 1, wherein the water-soluble thickener comprises at least one selected from the group consisting of natural gums, cellulose, starch-derived thickeners, acrylate-based polymers, PEG-based polymers, and PPG-based polymers.

5. The water-soluble thickener may be selected from the group consisting of carrageenan, xanthan gum, cassia gum, gellan gum, carob bean gum, agar, algin, guar gum, pectin, glucomannan, cellulose gum, and tamarind seed gum (Tamarindus Indica Seed Gum). Gum), microcrystalline cellulose, carboxymethyl cellulose, hydroxyethyl cellulose, corn starch, rice starch, sodium acrylate starch, hydrogenated starch, carbomer, polyacrylic acid, ammonium acryloyldimethyl taurate / VP copolymer, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, polyacrylate-13, acrylates / C10-30 alkyl acrylate crosspolymer, PPG-17 / IPDI / DMPA copolymer, acrylates / Beheneth 25 methacrylate copolymer, and PEG 240 / HDI copolymer bisdecyltetradeceth 20 ether.

6. The composition of claim 1, wherein the polyvinyl alcohol is present in an amount of 1 to 20% by weight, based on the total weight of the composition.

7. The composition of claim 1, comprising the water-soluble thickener in an amount of 0.1 to 5% by weight, based on the total weight of the composition.

8. 2. The composition according to claim 1, wherein the weight ratio of said polyvinyl alcohol to said water-soluble thickener is 1:0.01-0.

6.

9. The composition of claim 1, wherein the composition is applied to the skin at a thickness of 0.1 to 2 mm.

10. 2. The composition according to claim 1, wherein the thickness of the composition after drying is 10 to 25% of the thickness of the composition immediately after application to the skin.

11. 10. The composition of claim 1, wherein the composition contracts the skin for at least one hour.

12. 10. The composition of claim 1, wherein the composition dries to a moisture content of 3% or less within 15 minutes.

13. The composition of claim 1, wherein the composition has a duration of use of 15 minutes to 24 hours.

14. The composition of claim 1 , wherein the composition is a cosmetic composition.

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