Pulse rate estimation method, training method, exercise instruction apparatus, and pulse rate estimation system

Abstract

To provide a pulse rate estimation method and estimation system in ST or ST2 where an exercise time is short compared to a case of a conventional Ramp load, a training method that performs exercise using the pulse rate estimated by the estimation method as an index, and an exercise instruction apparatus and exercise instruction system capable of instructing exercise intensity using an individual's pulse rate in ST or ST2 as an index.SOLUTION: A pulse rate estimation method includes determining a descending start point at which the measured value of SpO2 begins to show a descending trend, or determining an inflection point at which the behavior of the value obtained by dividing blood oxygen concentration by pulse rate (SpO2 / pulse rate) changes while applying a constant load to a subject for 2 to 10 minutes such that the subject's pulse rate remains between 75% and 90% of the maximum heart rate, and estimating the pulse rate in ST or ST2 on the basis of these points. The present invention also provides an estimation system capable of implementing the estimation method, as well as a training method and an exercise instruction apparatus utilizing the estimation method.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention provides pulse rate Estimation method, training method, exercise instruction device, and pulse rate This paper relates to an estimation system. [Background technology]

[0002] Many reports have shown that the higher one's physical fitness, such as muscle strength and cardiopulmonary capacity, the higher one's health and survival rate, and the lower one's mortality rate (Non-Patent Document 1). To improve one's physical fitness, such as muscle strength and cardiopulmonary capacity, one must exercise at a moderate intensity or higher; for example, continuing to exercise at an insufficient intensity will not improve one's physical fitness. While the level of moderate-intensity exercise differs for each individual, it is known that the anaerobic threshold (AT) is a moderate-intensity exercise for all people. The term "anaerobic threshold" refers to the intensity at which, as the exercise intensity increases, the supply of oxygen required for muscle energy consumption can no longer keep up, and blood lactate begins to increase rapidly (see, for example, the Ministry of Health, Labor and Welfare website, e-Health Net).

[0003] Additionally, the respiratory compensation start point (RCP) is a standard for exercise intensity higher than the AT, which is the upper limit of exercise intensity that can be sustained before metabolic acidosis causes significant hyperventilation. Exercise intensities above the AT further increase the rate of increase in blood carbon dioxide, and further increases in exercise intensity result in a corresponding increase in blood carbon dioxide concentration. The RCP is the point at which the respiratory rate increases and actively expels the increased blood carbon dioxide that occurs with increasing exercise intensity. It is known that athletes and others seeking exceptional athletic performance can efficiently improve their physical abilities by exercising within the AT-RCP range, with the RCP as the upper limit, at an intensity of approximately 80-95% of the RCP.

[0004] To measure AT and RCP, a cardiopulmonary exercise stress test is required. A cardiopulmonary exercise stress test involves measuring oxygen intake and carbon dioxide output using a breath analyzer while applying a gradually increasing exercise load (ramp load) (see Non-Patent Document 2, p. 22, "3. Cardiopulmonary Exercise Stress Test"). Conventionally, to measure AT and RCP, a participant must exercise to the point of immobility under the supervision and guidance of a trainer while breathing through a mouthpiece connected to a breath gas measuring device. Because this required special equipment, this test could only be performed in hospitals, sports universities, research institutes, etc. The present applicant has proposed a method for estimating the optimal exercise intensity corresponding to AT (Patent Document 1) and a method for estimating the upper exercise intensity corresponding to RCP (Patent Document 2) from blood oxygen concentration (SpO2) measurements taken at different exercise loads while applying a ramp load. This method allows for a much simpler estimation of an individual's exercise intensity than conventional methods. Furthermore, the present applicant has proposed a blood oxygen concentration measurement probe capable of measuring blood oxygen concentration and heart rate (Patent Document 3). The present applicant has also obtained a registered trademark for the oxygen saturation threshold (SpO2 Threshold) to be used for the exercise intensity estimated from SpO2 measurements. Hereinafter, the optimal exercise intensity will also be referred to as "ST" and the upper exercise intensity as "ST2." All documents, patent applications, and technical standards described herein are incorporated by reference into this specification to the same extent as if each individual document, patent application, and technical standard were specifically and individually indicated as being incorporated by reference. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Patent No. 6990333 [Patent Document 2] Patent No. 7256328 [Patent Document 3] Patent No. 7425272 [Non-patent literature]

[0006] [Non-Patent Document 1] DZHLevett et al., “Perioperative cardiopulmonary exercise testing (CPET): clinical consensus guidelines on indications, tissue, conduct, and physiological interpretation”, British Journal of Anaesthesia, Volume 120, Issue 3, March 2018, Pages 484-500 [Non-patent document 2] Japanese Circulation Society Guidelines, "Guidelines for Rehabilitation in Cardiovascular Disease (2021 Revised Edition)," https: / / www.jacr.jp / cms / wp-content / uploads / 2015 / 04 / JCS2021_Makita2.pdf Summary of the Invention [Problem to be solved by the invention]

[0007] Whether it is exhaled gas analysis or blood oxygen concentration measurement, ST or ST2 To measure this, exercise with gradually increasing ramp load is required, and the exercise time should be approximately 15 to 20 minutes. The present invention allows for shorter exercise times compared to conventional ramp loads. ST or ST2 pulse rate The estimation method and system of pulse rate A training method that uses exercise as an indicator, pulse rate The present invention aims to provide an exercise instruction device and an exercise instruction system that can instruct exercise intensity using the above as an index. [Means for solving the problem]

[0008] The means for solving the problems of the present invention are as follows. 1. The subject is given a fixed load for 2 to 10 minutes that keeps the pulse rate at 75% to 90% of the maximum heart rate. The starting point of the downward trend in the measured blood oxygen concentration (SpO2) or the first bending point at which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes is determined. At the start of this descent or the first bend pulse rate the optimal exercise intensity of the subject Pulse rate in It is characterized in that it is estimated that pulse rate Estimation method. 2. Subjects were given a fixed load that kept their pulse rate at 75% to 90% of their maximum heart rate for 2 to 10 minutes, while blood oxygen concentration (SpO2) and pulse rate were measured simultaneously. Optimal exercise intensity estimated by the method described in 1. Pulse rate in determining a second inflection point beyond which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes, At the second bending point pulse rate the upper limit exercise intensity of the subject Pulse rate in It is characterized in that it is estimated that pulse rate Estimation method. 3. Estimated using the estimation method described in 1. or 2. pulse rate A training method characterized by performing exercise using the above as an index. 4. Estimated using the estimation method described in 1. or 2. pulse rate a storage means for storing the biometric information values ​​in the a measuring means capable of measuring the biological information value; a biological information value measured by the measuring means; Estimated pulse rate a calculation means for calculating exercise intensity by comparing the biological information value in an instruction means for instructing the exercise intensity calculated by the calculation means; An exercise instruction device comprising: 5. The measuring means is capable of measuring blood oxygen concentration; the instructing means is capable of instructing an exercise load based on information about the biological information value from the measuring means, The exercise instruction device described in 4. is characterized in that the calculation means is capable of calculating the starting point at which the measured blood oxygen concentration begins to show a downward trend, or the bending point at which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes when a fixed load is applied for 2 to 10 minutes at which the pulse rate is 75% to 90% of the maximum heart rate. 6. The exercise instruction device according to 4. or 5., characterized in that it is a wearable terminal. 7. A measuring unit that measures blood oxygen concentration (SpO2) and pulse rate; an instruction unit that indicates an exercise load amount that is a fixed load that causes the pulse rate to be 75% to 90% of the maximum heart rate; before Note a calculation unit that calculates the starting point at which the measured value of the blood oxygen concentration begins to show a downward trend when a fixed load is applied for 2 minutes or more and 10 minutes or less, or the first bending point at which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes; and At the start of the descent or the first bending point pulse rate Optimal exercise intensity Pulse rate in It is characterized in that it is estimated that pulse rate Estimation system. 8. The optimal exercise intensity Pulse rate in The second bending point beyond which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes. Pulse rate in of 、 Upper limit exercise intensity Pulse rate in It is assumed that the pulse rate Estimation system. [Effects of the Invention]

[0009] This invention allows you to exercise for 2 to 10 minutes. ST or ST2 pulse rate It is possible to estimate the number of people, such as members of a sports team or students at a physical education university. ST or ST2 When measuring, the measurement time per person can be shortened, so the number of people who can be measured per day can be increased. Ramp load exercise is exercise that gradually increases in strength even though you have not reached your physical or muscular limits. loadIn this invention, since it is only necessary to perform exercise with a fixed load for a certain period of time, it is possible that the person may give up on continuing the exercise midway and not be able to measure accurately. ST or ST2 This can reduce cases where the The present invention is based on 2-10 minutes of fixed load exercise. ST or ST2 pulse rate can be calculated more frequently than conventional methods. ST or ST2 By this invention, you can know your own ST or ST2 This is a revolutionary invention for health-conscious people who have incorporated exercise into their daily lives, as well as professional athletes and top amateur athletes who require high performance, as it allows people to exercise frequently. DETAILED DESCRIPTION OF THE INVENTION

[0010] Estimation methods and systems The first method of the present invention pulse rate The estimation method is as follows: The subject is given a fixed load for 2 to 10 minutes that keeps the pulse rate at 75% to 90% of the maximum heart rate. The test determines the starting point of the downward trend in the measured blood oxygen concentration (SpO2), or the inflection point at which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes. At the start of this descent or bending point pulse rate the optimal exercise intensity of the subject Pulse rate in The present invention is characterized in that it is estimated that:

[0011] The second method of the present invention is pulse rate The estimation method is as follows: Subjects were given a fixed load that kept their pulse rate between 75% and 90% of their maximum heart rate for between 2 and 10 minutes, while their blood oxygen concentration (SpO2) and pulse rate were measured simultaneously. Optimal exercise intensity estimated by the first method Pulse rate in determining an inflection point beyond which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes, At the bending point pulse ratethe upper limit exercise intensity of the subject Pulse rate in The present invention is characterized in that it is estimated that: In this specification, the expression "A to B (A and B are numbers)" means a numerical range including the values ​​of A and B, that is, A or more and B or less.

[0012] The blood oxygen concentration (SpO2) is the ratio of red blood cell hemoglobin in arterial blood bound to oxygen. SpO2 can be measured simply by attaching a blood oxygen concentration measuring probe of a measuring device (pulse oximeter) to a fingertip, wrist, etc. pulse rate The estimation method is non-invasive and therefore places little burden on the subject.

[0013] The estimation method of the present invention obtains blood oxygen concentration (SpO2) measurements while subjecting a subject to a fixed load for 2 to 10 minutes that keeps the pulse rate at 75% to 90% of the maximum heart rate. The pulse rate is also measured simultaneously. The estimation method of the present invention can also measure one or more types of biometric information, such as blood pressure, lactate concentration (in blood and sweat), and carbon dioxide concentration in exhaled breath, in addition to SpO2 and pulse rate. The estimation method of the present invention involves exercising for 2 to 10 minutes with a fixed load that will result in a pulse rate of 75% to 90% of the maximum heart rate, and the pulse rate at the start of exercise with a fixed load does not have to be 75% to 90% of the maximum heart rate. In other words, the estimation method of the present invention does not involve exercising for 2 to 10 minutes after the pulse rate during exercise has reached a target pulse rate (for example, 75% of the maximum heart rate). It is also possible to predict a fixed load that will result in a pulse rate of 75% to 90% of the maximum heart rate based on the subject's exercise habits, and exercise with the predicted fixed load, but if the predicted fixed load is outside the range of 75% to 90% of the maximum heart rate, pulse rate Therefore, it is preferable to measure in advance a fixed load at which the pulse rate is between 75% and 90% of the maximum heart rate.

[0014] In the estimation method of the present invention, exercise is performed with a fixed load that keeps the pulse rate at 75% to 90% of the maximum heart rate. The maximum heart rate can be a value used as a standard for aerobic exercise, and is generally expressed as 220 - age. However, for elderly people, a value such as 207 - (age x 0.5 to 0.7) can be used. Note that exercise that keeps the pulse rate at more than 90% of the maximum heart rate is high intensity and places a great burden on the subject.

[0015] In the estimation method of the present invention, the exercise method is not particularly limited, and a treadmill, a bicycle ergometer, a stepper, etc. can be used. In the estimation method of the present invention, the pulse rate during exercise and the exercise duration are not particularly limited as long as they are within the above-mentioned ranges. The higher the pulse rate and the longer the exercise duration, the more accurate the estimation. ST or ST2 pulse rate However, the exercise load during measurement is large. Therefore, the pulse rate during exercise is preferably 88% or less of the maximum heart rate, more preferably 86% or less, even more preferably 84% or less, even more preferably 82% or less, and even more preferably 80% or less. Furthermore, the exercise time is preferably 9 minutes or less, more preferably 8 minutes or less, even more preferably 7 minutes or less, even more preferably 6 minutes or less, and even more preferably 5 minutes or less. Pulse Rate and Exercise time The combinations may be, for example, 2 minutes 30 seconds or more when the heart rate is 75% or more but less than 80% of the maximum heart rate, or 2 minutes or more when the heart rate is 80% or more but less than 90% of the maximum heart rate. The estimation method of the present invention involves exercise under a fixed load, and the pulse rate during measurement should be kept within a certain range. However, it is preferable to set an upper limit for the pulse rate depending on the subject's gender, age, whether or not they exercise regularly, etc., and if the pulse rate exceeds the set upper limit, it is determined that a heavy load is being placed on the subject, and the measurement is stopped.

[0016] Measurements of SpO2 and the like can be performed continuously, but because measurements are taken while exercising, the measuring device may shift, resulting in inaccurate measurements. Therefore, it is preferable to use values ​​obtained by summarizing measurements taken intermittently at intervals of about 0.1 to 5 seconds over a period of about 1 to 30 seconds as the average or median. Furthermore, since the measured bioinformation values ​​typically change in only one direction as the exercise time increases—for example, SpO2 only decreases, and pulse rate only increases—it is possible to perform processing that does not use values ​​that show a change opposite to the normal state, or processing that does not use measurements that deviate by, for example, 10% or more from the immediately preceding measurement value or the average or median of measurements taken 2 to 5 times before the measurement.

[0017] The estimation method of the present invention may be, for example, a measuring unit for measuring blood oxygen concentration and pulse rate; an instruction unit that indicates an exercise load amount that is a fixed load that causes the pulse rate to be 75% to 90% of the maximum heart rate; before Note a calculation unit that calculates the starting point at which the measured value of the blood oxygen concentration begins to show a downward trend when a fixed load is applied for 2 minutes or more and 10 minutes or less, or the bending point at which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes; and At the start of the descent or the first bending point pulse rate Optimal exercise intensity Pulse rate in It is assumed that pulse rate This can be achieved by the estimation system.

[0018] The estimation system of the present invention may further include a memory unit for storing measurement values, a communication unit for exchanging data with the outside, a display unit for displaying instructions, etc. At least a part of the memory unit and the calculation unit may be a cloud system in which processing is performed by an external server communicating through the communication unit. Furthermore, the estimation system of the present invention may be implemented in a wearable device such as a smartphone, a smart watch, smart glasses, or earphones. ST or ST2 pulse rateThe above means may be implemented by installing an application having the estimation function or by connecting to a blood oxygen level measurement probe. The estimation system of the present invention can be configured by connecting a measurement device such as a pulse oximeter equipped with an instruction unit to training equipment such as a treadmill or bicycle ergometer at a sports gym, for example, by wire or wirelessly, and by measuring the blood oxygen level with the measurement unit (measurement device) while instructing the speed, incline, resistance, etc. of the exercise equipment, for example, the treadmill or bicycle ergometer, so that the exercise load is a fixed load that keeps the pulse rate during exercise at 75% to 90% of the maximum heart rate.

[0019] In the estimation system of the present invention, the pulse rate during exercise is preferably 88% or less of the maximum heart rate, more preferably 86% or less, even more preferably 84% or less, even more preferably 82% or less, and even more preferably 80% or less. The exercise time is preferably 9 minutes or less, more preferably 8 minutes or less, even more preferably 7 minutes or less, even more preferably 6 minutes or less, and even more preferably 5 minutes or less. Pulse Rate and Exercise time The combinations may be, for example, 2 minutes 30 seconds or more when the heart rate is 75% or more but less than 80% of the maximum heart rate, or 2 minutes or more when the heart rate is 80% or more but less than 90% of the maximum heart rate. The estimation system of the present invention can be configured by combining a measuring device such as a pulse oximeter that can measure blood oxygen concentration with a training device that allows exercise with a fixed load, so there is no need to use a specialized measuring device under the guidance of an expert, and it can be introduced, for example, in a sports gym.

[0020] Optimal exercise intensity Pulse rate in Estimation of The present invention pulse rate In the estimation method and estimation system of the optimal exercise intensity Pulse rate in is the point at which the measured value of blood oxygen concentration (SpO2) starts to show a downward trend, or the first bending point at which the behavior of the value obtained by dividing blood oxygen concentration by pulse rate (SpO2 / pulse rate) changes. pulse rate It is estimated as follows.

[0021] The method for determining the descent start point and the first bending point is not particularly limited, and various approximation processes, statistical processes, etc. are possible. For example, the following method can be mentioned. Method 1-1 for determining the starting point of descent (Method 1-1) A method for measuring SpO2 and pulse rate simultaneously and determining the start point of decline based on the change in SpO2 over time, comprising: This method involves exercising for 2 to 10 minutes with a fixed load that keeps the pulse rate at 75% to 90% of the maximum heart rate, and using the SpO2 value at the first time the pulse rate exceeds the target pulse rate after the first time it exceeds the target pulse rate as the reference value.The SpO2 measurement point immediately before the range where the SpO2 measurement value remains lower than this reference value for 5 or more consecutive seconds is determined as the starting point of the decline.

[0022] Method 1-2 for determining the starting point of descent (Method 1-2) A method for measuring SpO2 and pulse rate simultaneously and determining the start point of decline based on the change in SpO2 over time, comprising: This method involves exercising for 2 to 10 minutes with a fixed load that keeps the pulse rate at 75% to 90% of the maximum heart rate, and using the SpO2 value the first time the pulse rate exceeds the target pulse rate after the first time it exceeds the target pulse rate as the reference value. In the region where SpO2 measurements are lower than this reference value for 5 or more consecutive seconds, the intersection of the line connecting the highest and lowest SpO2 measurement points with the approximation line before said region is determined as the starting point of the decline. If there are two or more highest or lowest measurement points, the earliest value over time is used as the measurement point.

[0023] · Method 1-3 for determining the first bending point (Method 1-3) The pulse rate was measured at the same time as SpO2, and the pulse rate was used as the independent variable, and the value obtained by dividing SpO2 by the pulse rate (SpO2 / pulse rate) was used as the dependent variable. This method involves exercising for 2 to 10 minutes with a fixed load that keeps the pulse rate at 75% to 90% of the maximum heart rate, and determining the bending point from the intersection of regression lines 1-1 and 1-2 when the sum of the squared residuals of regression lines 1-1 and 1-2 is smallest, the nth measurement point, the n+1th measurement point, the midpoint between them (n+0.5), etc., when the sum of the squared residuals is smallest, using a combination of regression line 1-1 from the first measurement point to the nth measurement point (n≧2) and regression line 1-2 from the n+1th measurement point to the Nth measurement point (N≧n+2).

[0024] Second inflection point (maximum exercise intensity) The present invention pulse rate In the estimation method and estimation system of the above, Pulse rate in is the optimal exercise intensity estimated by the above method Pulse rate in At the second bending point, the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes after exceeding pulse rate It is estimated as follows.

[0025] The method for determining the second bending point is not particularly limited, and various approximation processes, statistical processes, etc. are possible. For example, the following method can be mentioned. Method 2 for determining the second bending point (Method 2) The pulse rate was measured simultaneously with SpO2, and the pulse rate was used as the independent variable, and the value obtained by dividing SpO2 by the pulse rate (SpO2 / pulse rate) was used as the dependent variable. Optimal exercise intensity Pulse rate in A method of determining the bending point by combining a regression line 2-1 for the measurement points from the first measurement point to the mth (m≧2) measurement point and a regression line 2-2 for the m+1th measurement point to the Mth measurement point (M≧m+2), and determining the bending point by using the intersection of the regression lines 2-1 and 2-2 when the sum of the squared residuals of the regression lines 2-1 and 2-2 is smallest, or the mth measurement point, the m+1th measurement point, or the midpoint between them (m+0.5) when the sum of the squared residuals is smallest.

[0026] In methods 1-1 and 1-2, the number of seconds during which the measured SpO2 value remains lower than the reference value (the SpO2 value when the pulse rate first exceeds the target pulse rate) should be 5 seconds or longer. The longer this number of seconds, the less likely it is that an incorrect starting point for a decline will be determined based on a measurement that deviates from the trend, but the longer the measurement time, the greater the physical strain on the subject. Therefore, the lower limit of this number of seconds is preferably 8 seconds or longer, more preferably 10 seconds or longer, and the upper limit is preferably 60 seconds or shorter, more preferably 50 seconds or shorter, and even more preferably 40 seconds or shorter.

[0027] Furthermore, to prevent erroneous judgment due to a single measurement error, it is preferable to make a judgment based on two or more consecutive measurement values. That is, when SpO2 measurement values ​​are measured as an average value over a period of about 1 to 30 seconds, it is preferable that the value of the number of seconds used to calculate the SpO2 measurement value (average value) x (number of measurements - 1) is 5 seconds or longer, and that two or more consecutive measurement points have values ​​lower than the reference value.

[0028] In Methods 1-3 and 2, if two minutes or more have elapsed since the start of exercise with a fixed load, and the sum of squared residuals of regression lines A and B1 is smallest for the first X measurement points, the combination of regression line A for the first measurement point through x and regression line B1 for the x+1 measurement point through x measurement points is also smallest for the first X+p measurement points obtained by continuing exercise. If this combination also smallests the sum of squared residuals for the first X measurement points through x and regression line B2 for the x+1 measurement point through x+p measurement points, a knee point can be determined and further exercise can be stopped. When stopping exercise midway in this way, X is preferably 5 or greater, and p is preferably 2 or greater. Furthermore, the measurement times for the first through x and x+1 measurement points through x measurement points are each preferably 20 seconds or greater, more preferably 30 seconds or greater, and even more preferably 40 seconds or greater. Furthermore, the measurement time from the Xth to the X+pth times is preferably 10 seconds or more, more preferably 15 seconds or more, and even more preferably 20 seconds or more.

[0029] Training methods The training method of the present invention is a method for determining the exercise intensity estimated by the above estimation method. Pulse rate in The exercise intensity may be either the optimum exercise intensity or the upper limit of exercise intensity. The estimation method of the present invention can be used to estimate the optimal exercise intensity or the upper limit of exercise intensity. Pulse rate in The optimal exercise intensity can be estimated. Pulse rate in is the exercise intensity at AT Pulse rate in , estimated upper exercise intensity Pulse rate in is the exercise intensity at RCP Pulse rate in These exercise intensities are similar to Pulse rate in By using this training method as an indicator, it is possible to improve physical strength efficiently.

[0030] ·Exercise instruction device The exercise instruction device of the present invention is pulse ratea storage means for storing the biological information value in the above, a measurement means for measuring the biological information value, and the biological information value measured by the measurement means; Estimated pulse rate and a means for comparing the biological information value in the measurement result with the biological information value in the measurement result, and for indicating an exercise intensity. The exercise intensity can be either an optimum exercise intensity or an upper limit exercise intensity, or both. The exercise instruction device of the present invention may also have a storage means such as a memory, a communication means, a display means, a calculation means such as a CPU, a battery, etc. At least a part of the storage means and the calculation means may be processed by an external server communicating through a communication unit. The form of the exercise instruction device of the present invention is not particularly limited, and for example, it may be built into a training device, or it may be an external terminal connected to a training device, or it may be a smartphone, a smart watch, smart glasses, earphones, etc., which can implement the above means by installing an application thereon. Among these, a wearable terminal such as a smart watch or smart glasses is preferable.

[0031] In the exercise instruction device of the present invention, the biological information values ​​to be measured and stored include, in addition to SpO2 and pulse rate, blood pressure, lactic acid concentration (in blood and sweat), carbon dioxide concentration in exhaled breath, etc., and one or more of these may be measured. Of these, it is preferable to measure and store SpO2 and pulse rate because they are easy to measure. The exercise instruction device of the present invention is pulse rate The calculation means compares the biological information value at the time of measurement with the biological information value measured by the measurement means to calculate the current biological information value. pulse rate It was estimated that pulse rate The difference between the estimated exercise intensity and the actual exercise intensity can be calculated. pulse rate It is preferable to be able to set weak / equal / strong etc. using this as an index. This allows the user to select an exercise intensity that suits their purpose depending on their physical condition, the number of days until a game etc. By exercising at the exercise intensity instructed by the exercise instruction device of the present invention, the user can train very efficiently.

[0032] Furthermore, it is preferable that the exercise instruction device of the present invention has a measuring means capable of measuring SpO2 and pulse rate, an instruction means capable of instructing the amount of exercise load based on the information, and a calculation means capable of calculating the starting point at which the measured blood oxygen concentration begins to show a downward trend, or the bending point at which the behavior of the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO2 / pulse rate) changes, when a fixed load that causes the pulse rate to be 75% to 90% of the maximum heart rate is applied for 2 minutes to 10 minutes. Such an exercise instruction device instructs the user to exercise at a fixed load that causes the pulse rate to be 75% to 90% of the maximum heart rate, thereby achieving the optimal exercise intensity for the user. Pulse rate in , and even upper limit exercise intensity Pulse rate in Therefore, for example, the estimated motion information instructed by the exercise instruction device of the present invention can be pulse rate If your physical ability improves by continuing to exercise at an intensity that is based on the index for a while, and you no longer expect to see much improvement in your physical ability at this exercise intensity, you can still use the latest ST or ST2 pulse rate This allows you to exercise at a higher intensity. [Example]

[0033] (Example) Exercise load method Equipment used: Ergometer Load method: Fixed load method Ergometer settings - crank speed 60 rpm The saddle was set so that the subject's knees were slightly bent when the pedals came down. Resting condition - Rest in a sitting position for 2 minutes (sitting on an ergometer) Warm-up condition - 50 watts for 5 minutes Stop condition - The load will end when one of the following conditions is met: 1) When lower limb fatigue makes it impossible to maintain 60 rpm of exercise 2) When the test administrator decides to stop the test 3) When SpO2 or pulse rate exceeds the set measurement range. Load unit: watt

[0034] Loading method: Ramp loading method Ergometer settings - crank speed 60 rpm The saddle was set so that the subject's knees were slightly bent when the pedals came down. Resting condition - Rest in a sitting position for 2 minutes (sitting on an ergometer) Warm-up condition - 50 watts for 5 minutes Exercise load conditions - Ramp load increase amount 10watt / min Stop condition - The load will end when one of the following conditions is met: 1) When lower limb fatigue makes it impossible to maintain 60 rpm of exercise 2) When the test administrator decides to stop the test 3) When SpO2 or pulse rate exceeds the set measurement range. Load unit: watt

[0035] (SpO2 and pulse rate measurement) Blood oxygen concentration (SpO2) and pulse rate were measured using a pulse oximeter (NellcorTM N-BSJ (Covidien Japan Co., Ltd.)). SpO2 and pulse rate were measured at 4-second intervals and averaged every 20 seconds. The test was performed with SpO2 in the range of 96-100% and a pulse rate upper limit of 160 beats / min.

[0036] Experiment 1 SpO2 and pulse rate were measured while applying a ramp load to subjects A to E. All subjects A to E were aged 50 or younger, and their maximum heart rate was 220 minus their age. One week after the ramp load measurements, SpO2 and pulse rate were measured in the same manner, except that a fixed load was applied for 4 minutes at 80% of the maximum heart rate. The fixed load at 80% of the maximum heart rate was determined from the pulse rate during the ramp load exercise.

[0037] Determining the bending point Measures pulse rate at the same time as SpO2, The pulse rate was the independent variable, and the value obtained by dividing SpO2 by the pulse rate (SpO2 / pulse rate) was the dependent variable. When a regression line 1-1 for the first measurement point to the Nth (N≧2) measurement point is combined with a regression line 1-2 for the N+1th measurement point to the last measurement point, the N+1th measurement point is defined as the first bending point at which the sum of the residual sum of squares of the two regression lines 1-1 and 1-2 is smallest, and this is the optimal exercise intensity (ST). Pulse rate in was estimated.

[0038] Estimated optimal exercise intensity Pulse rate in The optimal exercise intensity is calculated from the data of subsequent measurement points (N+1 to the last measurement point). Pulse rate in When the sum of the residual sums of squares of the two regression lines 2-1 and 2-2 is smallest, the N+M+2nd measurement point is defined as the second bending point, and this is the upper limit of exercise intensity (ST2). Pulse rate in was estimated.

[0039] Table 1 shows the pulse rates at the optimal exercise intensity (ST) and upper limit exercise intensity (ST2) estimated for fixed load exercise and ramp load exercise. [Table 1]

[0040] For all subjects, the pulse rates at the optimum exercise intensity and upper limit exercise intensity estimated by the fixed load exercise were very close to the optimum exercise intensity and upper limit exercise intensity estimated by the ramp load exercise. In other words, the estimation method of the present invention gave pulse rates almost equivalent to those obtained by the ramp load exercise even with the fixed load exercise. ST or ST2 pulse rate It was confirmed that it is possible to estimate

[0041] Experiment 2 For subject E (male, 47 years old), SpO2 and pulse rate were measured in the same manner as above, except that a fixed load was applied so that the pulse rate was 70% and 75% of the maximum heart rate. For the obtained SpO2 and pulse rate, the optimal exercise intensity (ST) was determined by changing the data used (fixed load time). Pulse rate in and upper exercise intensity (ST2) Pulse rate in was estimated. The difference between the estimated pulse rates at ST and ST2 and the baseline pulse rate, using the pulse rates at ST and ST2 estimated from the results of a 4-minute 80% fixed load as the reference, is shown in Table 2. Note that ST and ST2 for the same exercise intensity were estimated from the same data; for example, the first bending point (ST) and second bending point (ST2) were estimated from the data for the first minute of a 4-minute exercise for a 1-minute fixed load time, and from the data for the first 2 minutes of a 4-minute exercise for a 2-minute fixed load time.

[0042] [Table 2]

[0043] In the case of fixed-load exercise where the pulse rate was 70% of the maximum heart rate, the difference between the pulse rate at the estimated exercise intensity and the pulse rate at the exercise intensity estimated from a fixed load of 80% for 4 minutes was large, more than 20 beats per minute, and the accuracy of estimating exercise intensity was poor. During exercise at a fixed load where the pulse rate was 75% of the maximum heart rate, the difference between the pulse rate at the estimated exercise intensity and the pulse rate at the exercise intensity estimated from a fixed load of 80% for 4 minutes was kept within 16 beats per minute for exercise lasting 2 minutes or more, and within 14 beats per minute for exercise lasting 2 minutes and 30 seconds or more. When exercising at a fixed load where the pulse rate is 80% of the maximum heart rate, the difference between the pulse rate at an exercise intensity estimated from a 4-minute fixed load of 80% was within 1 beat / minute at the optimal exercise intensity for exercise of 2 minutes or more, and within 10 beats / minute at the upper limit of exercise intensity.It was also confirmed that the longer the exercise time, the smaller the difference in pulse rate, and the improved estimation accuracy.

Claims

1. Subjects were given a fixed load that kept their pulse rate at 75% to 90% of their maximum heart rate for 2 to 10 minutes, while blood oxygen levels (SpO ２ ) begins to show a downward trend, or the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO ２ determining the first inflection point at which the behavior of the heart rate (HR / HR) changes, A method for estimating exercise intensity, characterized in that the exercise intensity at the start of the descent or the first bending point is estimated to be the optimal exercise intensity for the subject.

2. Subjects were given a fixed load that kept their pulse rate at 75% to 90% of their maximum heart rate for 2 to 10 minutes, while blood oxygen levels (SpO ２ ) and measure the pulse rate at the same time. The optimal exercise intensity estimated by the method of claim 1 is exceeded, and the blood oxygen concentration divided by the pulse rate (SpO ２ determining a second inflection point at which the behavior of the heart rate (i.e., heart rate / pulse rate) changes; A method for estimating exercise intensity, comprising estimating the exercise intensity at the second bending point as the upper limit exercise intensity of the subject.

3. A training method comprising: performing exercise using the exercise intensity estimated by the estimation method according to claim 1 or 2 as an index.

4. a storage means for storing a biological information value at the exercise intensity estimated by the estimation method according to claim 1 or 2; a measuring means capable of measuring the biological information value; a calculation means for calculating an exercise intensity by comparing the biological information value measured by the measurement means with the biological information value at the exercise intensity; an instruction means for instructing the exercise intensity calculated by the calculation means; An exercise instruction device comprising:

5. the measuring means is capable of measuring blood oxygen concentration, the instructing means is capable of instructing an exercise load based on information about the biological information value from the measuring means, The calculation means calculates the point at which the measured value of the blood oxygen concentration starts to show a downward trend or the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO ２ 5. The exercise instruction device according to claim 4, wherein the device is capable of calculating a bending point at which the behavior of the heart rate (i.e., the heart rate) changes.

6. 5. The exercise instruction device according to claim 4, wherein the exercise instruction device is a wearable terminal.

7. Blood oxygen concentration (SpO ２ ) and a measuring unit for measuring the pulse rate; an instruction unit that indicates an exercise load amount that is a fixed load that causes a pulse rate to be 75% to 90% of a maximum heart rate; When a fixed load is applied for 2 to 10 minutes, the point at which the measured blood oxygen concentration begins to show a downward trend, or the value obtained by dividing the blood oxygen concentration by the pulse rate (SpO ２ a calculation unit for calculating the first bending point at which the behavior of the heart rate (i.e., heart rate) changes; and An exercise intensity estimation system characterized by estimating the exercise intensity at the starting point of the descent or the first bending point as the optimal exercise intensity.

8. If the exercise intensity exceeds the optimal level, the blood oxygen concentration divided by the pulse rate (SpO ２ 8. The system for estimating exercise intensity according to claim 7, wherein a second bending point at which the behavior of the heart rate (i.e., heart rate / pulse rate) changes is estimated to be the upper limit of exercise intensity.

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