Sunscreens that don't negatively impact the skin microbiome

Abstract

The present invention relates to microbiome friendly sunscreen or daily care compositions that contain certain UV filters, such as hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate.

Description

[Technical field]

[0001] The present invention relates to the use of a sunscreen or daily care composition comprising a certain UV-screening agent to increase the compatibility of the sunscreen or daily care composition with the skin microflora, preferably the human skin microflora.Furthermore, the present invention relates to a certain sunscreen or daily care composition suitable for a microflora-friendly application.Finally, the present invention relates to the use of a composition (A) comprising a certain UV-screening agent to produce a sunscreen or daily care composition compatible with the skin microflora, preferably the human skin microflora. [Background technology]

[0002] UV radiation has harmful effects on human skin. It is known that UV radiation increases the risk of skin cancer as well as causing acute effects such as sunburn of the skin. Furthermore, prolonged exposure to UV-A and UV-B light can cause phototoxic and photoallergic reactions in the skin and can accelerate skin aging.

[0003] To protect human skin from UV radiation, there are various sun-protective UV filters (also called UV absorbers), such as UV-A filters (also called UVA filters), UV-B filters (also called UVB filters) and broadband filters. These filters are added to sunscreens or daily care compositions. UV filters are either organic or inorganic particulate or non-particulate compounds, all of which have high absorption efficiency in the UV light range. Generally, UV light can be divided into UV-A radiation (320-400 nm) and UV-B radiation (290-320 nm). UV filters are divided into UV-A filters and UV-B filters according to the position of the absorption maximum. If a UV filter absorbs both UV-A and UV-B light, it is called a broadband absorber.

[0004] Since 2006, the European Commission has recommended that all sunscreen or daily care compositions should have a UV-A protection factor (SPF) of at least one third of the declared SPF (the sun protection factor mainly refers to UV-B protection).

[0005] Human skin contains millions of bacteria, fungi and viruses that constitute the skin microbiome. These organisms play an essential role in defense against, for example, invading pathogens. If the barrier provided by these organisms is destroyed, humans become vulnerable to invading pathogens. For example, it is known that compounds contained in cosmetics tend to destroy said barrier.

[0006] The major products on the market, even if they provide both UVB and UVA protection according to the current standards, are required to improve, for example, the skin microbiota friendliness of sunscreens. Since users typically need to maintain a well-balanced skin microbiota in parallel with UV protection, the skin microbiota friendliness is an important performance indicator for the end consumer. In addition, many sunscreen or daily care compositions contain UV filters and other ingredients, such as dispersants, which, although approved for use in leave-on compositions, are frequently debated due to some concerns about their safety and possible skin sensitization in humans, especially for daily use. Summary of the Invention [Problem to be solved by the invention]

[0007] Against this background, there remains a need for a sunscreen or daily care composition for daily use that provides efficient sun protection and a well-balanced skin microflora. In particular, it was an object of the present invention to provide a sunscreen or daily care composition comprising a UV-screening agent that does not have a negative effect on the microflora. It was also an object of the present invention to provide a sunscreen or daily care composition comprising a UV-screening agent for use in a method for increasing the compatibility of a sunscreen or daily care composition with the skin microflora. It was also an object of the present invention to provide a method for producing a sunscreen or daily care composition that does not have a negative effect on the skin microflora. Finally, it was an object of the present invention to provide a composition (A) comprising a UV-screening agent for a method for producing a sunscreen or daily care composition that does not have a negative effect on the skin microflora. [Means for solving the problem]

[0008] Surprisingly, it has been found that at least one of these objectives can be achieved by the sunscreen or daily care composition and / or compositions according to the invention.

[0009] Thus, according to one aspect, the invention relates to the use of a sunscreen or daily care composition comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate, also known as DHHB), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine, also known as BEMT), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid, also known as PBSA), terephthalylidene dicamphorsulfonic acid (also known as TDSA), drometrizole trisiloxane (also known as DTS) and mixtures thereof, to increase the compatibility of the sunscreen or daily composition with the skin microflora, preferably with the human skin microflora.

[0010] In the following, preferred embodiments of the above uses are described in more detail, it being understood that each preferred embodiment is suitable not only on its own but also in combination with other preferred embodiments.

[0011] In a preferred embodiment A1a of the first aspect, the sunscreen or daily care composition comprises 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate), optionally further comprising 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid and / or drometrizole trisiloxane.

[0012] In a preferred embodiment A1b of the first aspect, the sunscreen or daily care composition comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine) and optionally 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid and / or drometrizole trisiloxane.

[0013] In a preferred embodiment A1c of the first aspect, the sunscreen or daily care composition comprises 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) and optionally 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine), 2-[4-(Diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate), terephthalidenedicamphorsulfonic acid and / or drometrizole trisiloxane.

[0014] In a preferred embodiment A1d of the first aspect, the sunscreen or daily care composition comprises terephthalylidene dicamphorsulfonic acid and optionally 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid) and / or drometrizole trisiloxane.

[0015] In a preferred embodiment A1e of the first aspect, the sunscreen or daily care composition comprises drometrizole trisiloxane and optionally 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid) and / or terephthalylidene dicamphorsulfonic acid.

[0016] In a preferred embodiment A2 of the first aspect, a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof is present in the sunscreen or daily care composition and in the presence of Propionibacterium acnes on the skin. acnes, Propionibacterium granulosum, Propionibacterium avidum, Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus hominis, Staphylococcus xylosus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus saccharolyticus, Staphylococcus conii conii, Staphylococcus auricularis, Micrococcus luteus, Corynebacterium minutissimum, Corynebacterium jeikeiumjeikeium, Corynebacterium tuberculostearicum, Corynebacterium fastidiosum, Corynebacterium simulans, Corynebacterium amycolatum, Corynebacterium xerosis, Streptococcus mitis, Streptococcus sanguinis, Streptococcus oralis, Brevibacterium spp., Pseudomonas spp. spp. and mixtures thereof, preferably Staphylococcus epidermidis, and / or The present invention provides an improved compatibility of a sunscreen or daily care composition with a fungal population on the skin selected from the group consisting of Malassezia furfur, Malassezia restricta, Malassezia globosa, Candida spp., and mixtures thereof.

[0017] In a preferred embodiment A3 of the first aspect, the sunscreen or daily care composition preferably comprises 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyltriazone), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamidotriazone or DBT), dimethicone diethylbenzylmalonate (INCI Polysilicone-15) and mixtures thereof, in particular 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyl Triazone or EHT), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamido Triazone or DBT) and mixtures thereof.

[0018] In a preferred embodiment A4 of the first aspect, the sunscreen or daily care composition comprises 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol), 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 5,6,5',6'-tetraphenyl-3-3'-(1,4-phenylene)bis(1,2,4-triazine) (INCI phenylenebis-diphenyltriazine), 1,1'-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]methanone (INCI In one embodiment, the composition further comprises at least one organic microparticulated UV filter selected from the group consisting of bis-(diethylaminohydroxybenzoylbenzoyl)piperazine), preferably 2,2'-methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazol-2-yl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine).

[0019] In a preferred embodiment A5 of the first aspect, the at least one organic microparticulated UV filter is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decylglucoside) and / or the at least one organic microparticulated UV filter is dispersed in a polyglycerol monoalkyl ester.

[0020] In a preferred embodiment A6 of the first aspect, the sunscreen or daily care composition further comprises at least one additional UVA screening agent, preferably selected from the group consisting of disodium phenyl dibenzimidazole tetrasulfonate, 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butyl Methoxydibenzoylmethane) and mixtures thereof, in particular 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butyl Methoxydibenzoylmethane).

[0021] In a preferred embodiment A7 of the first aspect, the sunscreen or daily care composition does not contain zinc oxide (ZnO).

[0022] In a preferred embodiment A8 of the first aspect, the sunscreen or daily care composition comprises hexyl 2-[4-(diethylamino)-2 hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate) in an amount of 0.1 to 10% by weight, preferably 0.5 to 8% by weight, in particular 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0023] In a preferred embodiment A9 of the first aspect, the sunscreen or daily care composition comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine) in an amount of 0.1 to 7% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition, and / or 2-Phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) in an amount of 0.1 to 6% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition, and / or Terephthalylidene dicamphorsulfonic acid (TDSA) in an amount of 0.1 to 10% by weight, preferably 0.2 to 5% by weight, based on the total weight of the sunscreen or daily care composition; and / or Drometrizole trisiloxane (DTS) is included in an amount of 0.1 to 10% by weight, preferably 0.2 to 6% by weight, based on the total weight of the sunscreen or daily care composition.

[0024] In a preferred embodiment A10 of the first aspect, the sunscreen or daily care composition comprises at least one organic microparticulated UV filter in an amount of 0.1 to 10% by weight, preferably 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0025] In a preferred embodiment A11 of the first aspect, the sunscreen or daily care composition comprises 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyltriazone) in an amount of 0.1 to 5% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0026] In a preferred embodiment A12 of the first aspect, the sunscreen or daily care composition further comprises a dermatologically acceptable emulsifier, thickener and / or emollient.

[0027] In a preferred embodiment A13 of the first aspect, the sunscreen or daily care composition does not contain 2-cyano-3,3-diphenylprop-2-enoic acid 2-ethylhexyl ester (INCI Octocrylene), (RS)-2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Ethylhexyl Methoxycinnamate), 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Isoamyl p-methoxycinnamate) and / or 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate (INCI Homosalate).

[0028] In a second aspect, the present invention provides a sunscreen or daily care composition comprising: 0.1 to 10% by weight, preferably 0.5 to 5% by weight, of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoyl hexyl benzoate), 0.1 to 8% by weight, preferably 0.5 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 5% by weight, preferably 0.5 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), 0.1 to 5% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0 to 10% by weight, preferably 0.1 to 5% by weight, of 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 3 to 15% by weight, preferably 5 to 10% by weight, of glycerol (also known as glycerin); Each based on the total weight of the sunscreen or daily care composition; It further relates to a sunscreen or daily care composition which does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI isoamyl p-methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), zinc oxide and mixtures thereof.

[0029] In a preferred embodiment B1 of the second aspect, 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol)] is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decylglucoside).

[0030] In a third aspect, the present invention relates to the use of a composition (A) comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, for producing a sunscreen or daily care composition compatible with the skin microflora, preferably the human skin microflora.

[0031] In a preferred embodiment C1 of the third aspect, the sunscreen or daily care composition further comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine) and / or 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid). DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0032] Before describing exemplary embodiments of the present invention in detail, definitions that are important for understanding the present invention are provided.

[0033] As used in this specification and the appended claims, the singular forms "a" and "an" also include the respective plural forms, unless the context clearly dictates otherwise. In the context of the present invention, the terms "about" and "approximately" refer to a margin of accuracy that a person skilled in the art would understand to still ensure the technical effect of the feature in question. This term typically indicates a deviation of ±15%, preferably ±10%, more preferably ±5%, and even more preferably ±2% from the indicated numerical value. The term "comprising" is to be understood as non-limiting. The term "comprising" for the purposes of the present invention is considered to be a preferred embodiment of the term "comprising of". In the following, when a group is defined to include at least a certain number of embodiments, this preferably also means to include a group consisting only of these embodiments. Furthermore, the terms "first", "second", "third" or "(a)", "(b)", "(c)", "(d)" and similar terms in this specification and the appended claims are used to distinguish between similar elements and do not necessarily describe a sequential or chronological order. It is to be understood that the terms so used are interchangeable under appropriate circumstances and that the embodiments of the invention described herein can be performed in other orders than those described or illustrated herein. When terms such as "first", "second", "third" or "(a)", "(b)", "(c)", "(d)", "i", "ii" and the like refer to steps of a method or use or assay, unless otherwise specified in this application, as hereinbefore or hereinafter described, there is no time or consistency between the steps, i.e., the steps may be performed simultaneously or there may be a time interval of seconds, minutes, hours, days, weeks, months or even years between such steps. It is to be understood that the invention is not limited to the particular methodologies, procedures, reagents, and the like described herein, as these may vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the scope of the invention, which will be limited only by the scope of the appended claims.Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art.

[0034] As used herein, the terms "does not comprise", "does not contain" or "free of", in the context that the composition of the invention does not comprise a particular compound or group of compounds (which may be groups combined under a collective term), means that the composition does not comprise said compound or group of compounds in an amount greater than 0.8% by weight based on the total weight of the composition. Furthermore, it is preferred that the composition according to the invention does not comprise said compound or group of compounds in an amount greater than 0.5% by weight, and preferably the composition is completely free of said compound or group of compounds.

[0035] When referring to weight percentages of compositions and ingredients contained therein, it is to be understood that in accordance with the present invention, the total amount of ingredients does not exceed 100% (± 1% rounded off).

[0036] The term "sunscreen composition" or "sunscreen" refers to any topical product that can absorb a certain portion of UV radiation and also reflect and scatter it. Therefore, it should be understood that the term "sunscreen composition" not only includes sunscreen compositions, but also includes any cosmetic composition that provides UV protection. The term "topical product" refers to a product that is applied to the skin, and can refer to, for example, a spray, a lotion, a cream, an oil, a foam, a powder, or a gel. According to the present invention, the sunscreen composition can include one or more active agents, such as organic and inorganic UV filters, and other ingredients or additives, such as emulsifiers, emollients, viscosity modifiers, stabilizers, preservatives, or fragrances.

[0037] The term "daily care composition" refers to any topical product used as a daily care product for the human body, for example, face or body, which can absorb a certain portion of UV radiation and also reflect and scatter it.The daily care composition can contain one or more active agents, for example, organic and / or inorganic UV screening agents, and other ingredients or additives, for example, emulsifiers, emollients, viscosity adjusters, stabilizers, preservatives or fragrances.Suitable daily care compositions are according to the present invention, for example, leave-on face and body care products.

[0038] Leave-on products suitable for the face and body are, for example, sunscreen compositions, decorative preparations and skin care preparations.

[0039] Suitable decorative preparations are, for example, lipsticks, nail varnishes, eye shadows, mascaras, dry and moist make-up products, rouge, powders, depilatories and suntan lotions.

[0040] Suitable skin care preparations are, for example, moisturizing, refining and lifting preparations. The daily care compositions mentioned can be in the form of creams, ointments, pastes, foams, gels, lotions, powders, make-ups, sprays, sticks or aerosols.

[0041] The term "UV filter" or "ultraviolet filter" as used herein refers to an organic or inorganic compound that can absorb and also reflect and scatter UV radiation produced by sunlight. UV filters can be classified as UV-A, UV-B or broadband filters depending on their UV protection curve.

[0042] The term "emollient" refers to certain cosmetic oils used to protect, moisturize and lubricate the skin. The word emollient comes from the Latin mollire, which means to soften. Generally, emollients prevent the evaporation of water from the skin by forming an occlusive coating. They can be divided into different groups according to their polarity index.

[0043] The term "polarity index" refers to non-polar or polar oils. Non-polar oils are mainly based on hydrocarbons and lack electronegative elements such as oxygen. In contrast, polar oils contain heteroatoms with different electronegativities, resulting in a dipole moment. However, this type of oil is still insoluble in water, i.e., hydrophobic. The polarity index can be determined by measuring the interfacial tension between the corresponding oil and water.

[0044] The term "sensitive skin" refers to skin whose natural barrier function is weakened and disrupted by triggers, which can be, for example, cold weather, extremely hot water, and potentially dangerous ingredients contained in sunscreen or daily care compositions.

[0045] The term "sun protection factor (SPF)" as used herein indicates how well a sunscreen composition protects the skin, mainly from UV-B radiation. Specifically, this index indicates how long the protected skin can be exposed to sunlight without sunburn, compared to untreated skin. For example, if a sunscreen composition with SPF 15 is evenly applied to human skin that would normally sunburn after 10 minutes in the sun, the sunscreen will allow the person skilled in the art to stay in the sun for 15 times longer. In other words, SPF 15 refers to a sunscreen that is applied to a thickness of 2 milligrams per square centimeter (mg / cm 2This means that if a 15-fold reduction in UV radiation were to reach the skin, assuming it were applied evenly at a dose of 10 ...

[0046] The definition of "broadband" protection (also called broad spectrum or broad-spectrum protection) is based on the "critical wavelength". To cover the broad band, UV-B and UV-A protection must be provided. According to US requirements, the critical wavelength must be at least 370 nm to achieve broad-spectrum protection. The term "critical wavelength" is defined as the wavelength at which the area under the UV protection curve (protection rate vs. wavelength) is 90% of the total area under the curve in the UV region (290-400 nm). For example, a critical wavelength of 370 nm indicates that the protection provided by the sunscreen composition is not limited to UV-B wavelengths, i.e., 290-320 nm, but extends up to 370 nm, reaching 90% of the total area under the protection curve in the UV region at 370 nm.

[0047] Furthermore, in Europe, the European Commission has recommended that all sunscreen or cosmetic compositions should have a UV-A protection factor of at least one-third of the declared sunscreen protection factor (SPF); for example, if a sunscreen composition has an SPF of 30, the UVA protection factor should be at least 10.

[0048] The term "administering" refers to the application of a sunscreen or daily care composition to human skin.

[0049] In the following, preferred embodiments of sunscreen or daily care compositions and their uses (e.g. in a method for increasing the compatibility of a sunscreen or daily composition with the skin microbiota) and / or the use of a composition comprising DHHB to produce a sunscreen or daily care composition compatible with the skin microbiota are described. It is to be understood that the preferred embodiments of the present invention are preferred both alone and in combination with each other.

[0050] As mentioned above, the present invention relates in one embodiment to the use of a sunscreen or daily care composition comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (also known as TDSA), drometrizole trisiloxane (also known as DTS) and mixtures thereof, to increase the compatibility of the sunscreen or daily composition with the skin microflora, preferably with the human skin microflora.

[0051] As mentioned above, the skin microbiota is composed of a great number of organisms that are important for example to protect mammals (such as humans) against pathogens. It is known that some compounds have a negative effect on said skin microbiota. According to the present invention, "increasing the compatibility of a sunscreen or daily composition with the skin microbiota" is understood to mean that a composition according to the present invention that contains one of the given UV-screening agents has a better microbial population than a strictly identical composition that does not contain the given UV-screening agent. Suitable representatives of the microorganisms of the skin microbiota are, for example, Staphylococcus epidermidis, Micrococcus luteus and Corynebacterium jeikeium.

[0052] In the context of the present invention, the following preferred embodiments for sunscreen or daily care compositions are suitable, it being understood that each preferred embodiment is suitable not only on its own but also in combination with other preferred embodiments.

[0053] In a preferred embodiment, 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI UV filters selected from the group consisting of phenylbenzimidazole sulfonic acid (TBS), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, increase the compatibility of the sunscreen or daily care composition with the long-term resident human skin microbiota (also known as the human skin microflora), which consists mainly of gram-positive bacteria, in particular the common Staphylococcus, Corynebacterium, Propionibacterium, Micrococcus, Streptococcus and Brevibacterium, as well as gram-negative bacteria, such as Pseudomonas, and also yeasts, such as the genus Malassezia (formerly Pityrosporum) or Candida. Of particular relevance to the healthy resident microflora are Propionibacterium acnes, Propionibacterium granulosum, Propionibacterium avidum, Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus hominis, Staphylococcus xylosus, Staphylococcus purpurea ...xylosus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus saccharolyticus, Staphylococcus conii, Staphylococcus auricularis, Micrococcus luteus, Corynebacterium minutissimum, Corynebacterium jeikeium, Corynebacterium fastidiosum, Corynebacterium simulans simulans, Corynebacterium amycolatum, Corynebacterium xerosis, Streptococcus mitis, Streptococcus sanguinis, Streptococcus oralis, Brevibacterium spp., Pseudomonas spp., Malassezia furfur, Malassezia restricta, Malassezia globosa, Candida spp. and mixtures thereof. In particular, Staphylococcus epidermidis, Micrococcus luteus and / or Corynebacterium jacchus are preferred.It is preferred that the compatibility with Staphylococcus jeikeium, and especially Staphylococcus epidermidis, be increased.

[0054] In a preferred embodiment, a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof is preferably used in combination with the sunscreen or daily care composition to inhibit Propionibacterium acnes, Propionibacterium granulosum ... granulosum, Propionibacterium avidum, Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus hominis, Staphylococcus xylosus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus saccharolyticus, Staphylococcus conii, Staphylococcus auricularis auricularis, Micrococcus luteus, Corynebacterium minutissimum, Corynebacterium jeikeiumand mixtures thereof. More preferably, there is increased compatibility with populations of Staphylococcus epidermidis, Micrococcus luteus and / or Corynebacterium jeikeium, especially populations of Staphylococcus epidermidis.

[0055] In this context, the relevance of increasing comparability with the skin microbiota is exemplified with Staphylococcus epidermidis as follows.

[0056] It is to be understood that the compatibility of a sunscreen or daily care composition (e.g. a composition of the invention comprising DHHB, BEMT, PBSA, TDSA and / or DTS) with the skin microflora is increased if the Staphylococcus epidermidis count determined after 24 hours is higher than the Staphylococcus epidermidis count determined after 24 hours of a strictly identical composition but without the given UV screening agent (e.g. DHHB, BEMT, PBSA, TDSA and / or DTS). It is further to be understood that the determination of the respective Staphylococcus epidermidis count must be carried out in an equivalent manner.

[0057] Preferably, the determination of the bacterial count is carried out in vitro, where a subculture of Staphylococcus epidermidis on tryptic soy agar is suspended in tryptic soy broth and incubated at 36°C for 24 hours (overnight culture). The preparation to be tested is spiked (T0) with a bacterial suspension (a dilution of an overnight culture of S. epidermidis in sodium chloride). At the end of the 24-hour contact, each sample is spread on the surface of a tryptone soy agar plate and incubated at 36° for 2 days before counting the microorganisms. Finally, the total number of colony forming units (cfu / mL) on each agar plate is counted for all test conditions.

[0058] In a preferred embodiment, the UV screening agent selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof is preferably used in combination with the sunscreen or daily care composition and in combination with the antibacterial agents Malassezia furfur, Malassezia restricta, Malassezia globosa on the skin. globosa, Candida spp., and mixtures thereof.

[0059] Preferably, the UV screening agent selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, is preferably used in the sunscreen or daily care composition and in the treatment of Propionibacterium acnes, Propionibacterium granulosum ... granulosum, Propionibacterium avidum, Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus hominis, Staphylococcus xylosus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus saccharolyticus, Staphylococcus conii, Staphylococcus auricularis auricularis, Micrococcus luteus, Corynebacterium minutissimum, Corynebacterium jeikeiumjeikeium, Corynebacterium fastidiosum, Corynebacterium simulans, Corynebacterium amycolatum, Corynebacterium xerosis, Streptococcus mitis, Streptococcus sanguinis, Streptococcus oralis, Brevibacterium spp., Pseudomonas spp., Malassezia furfur, Malassezia restricta restricta, Malassezia globosa, Candida spp. and mixtures thereof, more preferably selected from the group consisting of Staphylococcus epidermidis, Micrococcus luteus and / or Corynebacterium jeikeium and mixtures thereof.

[0060] In a preferred embodiment, the sunscreen or daily care composition comprises hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate).

[0061] In a preferred embodiment, the sunscreen or daily care composition comprises 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate) and further 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine) and / or 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid).

[0062] In a preferred embodiment, the sunscreen or daily care composition comprises 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate) and optionally further 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA) and / or drometrizole trisiloxane (DTS).

[0063] In a preferred embodiment, the sunscreen or daily care composition comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine) and optionally 2-[4-(Diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate), 2-Phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), Terephthalylidene Dicamphorsulfonic Acid and / or Drometrizole Trisiloxane.

[0064] In a preferred embodiment, the sunscreen or daily care composition comprises 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) and optionally 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine), 2-[4-(Diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate), terephthalidenedicamphorsulfonic acid and / or drometrizole trisiloxane.

[0065] In a preferred embodiment, the sunscreen or daily care composition comprises terephthalylidene dicamphorsulfonic acid and optionally 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid) and / or drometrizole trisiloxane.

[0066] In a preferred embodiment, the sunscreen or daily care composition comprises drometrizole trisiloxane and optionally 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid) and / or terephthalylidene dicamphorsulfonic acid.

[0067] It is particularly preferred that the sunscreen or daily care composition comprises 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine) and 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid).

[0068] In a preferred embodiment, the sunscreen or daily care composition preferably contains 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyl Triazone), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamido Triazone or DBT), dimethicone diethyl benzyl malonate (INCI Polysilicone-15) and mixtures thereof, more preferably selected from the group consisting of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone or EHT), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl) ester (INCI Diethylhexylbutamido Triazone or DBT) and mixtures thereof, in particular 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI ethylhexyltriazone or EHT).

[0069] In a preferred embodiment, the sunscreen or daily care composition comprises 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol), 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 5,6,5',6'-tetraphenyl-3-3'-(1,4-phenylene)bis(1,2,4-triazine) (INCI phenylenebis-diphenyltriazine), 1,1'-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]methanone (INCI In one embodiment, the composition further comprises at least one organic microparticulated UV filter selected from the group consisting of bis-(diethylaminohydroxybenzoylbenzoyl)piperazine), preferably 2,2'-methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazol-2-yl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine).

[0070] Preferably, the at least one organic microparticulated UV filter is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decyl glucoside).

[0071] Preferably, at least one organic microparticulated UV filter is dispersed in the polyglycerol monoalkyl ester.

[0072] Preferably, the polyglycerol monoalkyl ester is selected from the group consisting of decaglyceryl caprate, decaglyceryl monolaurate, decaglyceryl myristate, decaglyceryl oleate, decaglyceryl stearate, decaglyceryl isostearate, hexaglyceryl caprate, hexaglyceryl laurate, hexaglyceryl myristate, hexaglyceryl oleate, hexaglyceryl stearate, hexaglyceryl isostearate, pentaglyceryl caprate, pentaglyceryl laurate, pentaglyceryl myristate, pentaglyceryl oleate, pentaglyceryl stearate, pentaglyceryl isostearate and mixtures thereof, more preferably, the at least one polyglycerol monoalkyl ester is decaglyceryl monolaurate (INCI Polyglyceryl-10 Laurate). The polyglycerol monoalkyl ester preferably has an HLB (hydrophilic-lipophilic balance) of at least 14.5, more preferably an HLB of at least 15. The HLB value may be determined by any means known in the art.

[0073] When the HLB of polyglycerol monoalkyl ester is less than 14.5, it may take longer time to disperse organic microparticulated UV screening agent (e.g. methylene bis-benzotriazolyl tetramethylbutylphenol) in water phase components.Examples of polyglycerol monoalkyl ester with average polymerization degree of 5 or more and HLB of 14.5 or more can include decaglyceryl caprate, decaglyceryl monolaurate, decaglyceryl myristate, decaglyceryl oleate, decaglyceryl stearate, decaglyceryl isostearate, hexaglyceryl laurate, pentaglyceryl laurate, pentaglyceryl myristate, pentaglyceryl stearate and pentaglyceryl oleate, and examples of polyglycerol monoalkyl ester with HLB of 15 or more can include decaglyceryl caprate and decaglyceryl monolaurate.

[0074] Any known process suitable for preparing microparticles can be used to prepare at least one organic microparticulated UV filter (e.g., methylene bis-benzotriazolyl tetramethylbutylphenol).Preferably, methylene bis-benzotriazolyl tetramethylbutylphenol, a water-insoluble organic compound (solubility in the ng / L range), is present in a microparticulated state, and more preferably is prepared by a wet milling process.

[0075] As a milling device for preparing the at least one organic microparticulated UV filter (e.g., methylene bis-benzotriazolyl tetramethyl butyl phenol), for example, a jet mill, a ball mill, a vibrating mill or a hammer mill, preferably a high speed mixing mill, can be used.

[0076] At least one organic micronized UV filter (e.g., methylene bis-benzotriazolyl tetramethylbutylphenol) is micronized to the desired average particle size, preferably in a ball mill, in the presence of water and a polyglycerol monoalkyl ester, such as polyglyceryl-10 laurate, which acts as a dispersant.

[0077] In a preferred embodiment, the sunscreen or daily care composition further comprises at least one additional UVA filter, preferably selected from the group consisting of disodium phenyldibenzimidazole tetrasulfonate, 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butyl Methoxydibenzoylmethane) and mixtures thereof, in particular 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butyl Methoxydibenzoylmethane).

[0078] In a preferred embodiment, the sunscreen or daily care composition does not contain zinc oxide (ZnO). In a preferred embodiment, the sunscreen or daily care composition does not contain a zinc derivative compound. According to the present invention, a zinc derivative compound means any compound that contains a zinc atom.

[0079] In a preferred embodiment, the sunscreen or daily care composition does not contain a zinc salt. In a particularly preferred embodiment, the sunscreen or daily care composition does not contain a zinc salt of pyrrolidone carboxylic acid.

[0080] In a preferred embodiment, the sunscreen or daily care composition is paraben-free.

[0081] In a preferred embodiment, the sunscreen or daily care composition does not contain PVP (polyvinylpyrrolidone) polymers and VP (vinylpyrrolidone) derivatives such as vinylpyrrolidone / hexadecene copolymer, VP / eicosene copolymer, triacontanyl PVP.

[0082] In a preferred embodiment, the sunscreen or daily care composition does not contain acrylic acid based polymers, such as compounds including but not limited to INCI Carbomer, C10 / 30 Alkyl Acrylate Crosspolymer.

[0083] In a preferred embodiment, the sunscreen or daily care composition comprises C2 to C 12 -Alkanediols, preferably 1,2-C 12 -Alkanediol or 1,3-C2-C 12 -alkanediols, more preferably 1,2-C 10 -Alkanediol or 1,3-C2-C 10 -Alkanediols, especially 1,2-C 10 Preferably, the sunscreen or daily care composition further comprises a C2-C8 alkanediol or a 1,2-C2-C8 alkanediol. 12-alkanediol in an amount of 0.5 to 10% by weight, more preferably 1 to 8% by weight, based on the total weight of the sunscreen or daily care composition.

[0084] In a preferred embodiment, the sunscreen or daily care composition further comprises glycerol (also known as glycerin), preferably in an amount of 3 to 15% by weight, more preferably 4 to 10% by weight, even more preferably 5 to 10% by weight, especially 5 to 8% by weight, based on the total weight of the sunscreen or daily care composition.

[0085] In a preferred embodiment, the sunscreen or daily care composition comprises sodium stearoyl glutamate in an amount of 0.1-2% by weight, preferably 1-2% by weight or 0.3-1% by weight, in particular 0.2-1% by weight, based on the total weight of the sunscreen or daily care composition.

[0086] In a preferred embodiment, the sunscreen or daily care composition comprises a monoester of stearic acid and glycerin (e.g., glyceryl stearate SE) in an amount of 1 to 4% by weight, preferably 1.5 to 3% by weight, based on the total weight of the sunscreen or daily care composition.

[0087] In a preferred embodiment, the sunscreen or daily care composition comprises hexyl 2-[4-(diethylamino)-2 hydroxybenzoyl]benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate) in an amount of 0.1 to 10% by weight, preferably 0.5 to 8% by weight, in particular 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0088] In a preferred embodiment, the sunscreen or daily care composition comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine) in an amount of 0.1 to 10% by weight, preferably 0.1 to 7% by weight, in particular 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0089] In a preferred embodiment, the sunscreen or daily care composition comprises 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) in an amount of 0.1 to 8% by weight, preferably 0.1 to 6% by weight, in particular 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0090] In a preferred embodiment, the sunscreen or daily care composition comprises terephthalylidene dicamphorsulfonic acid (TDSA) in an amount of 0.1 to 10% by weight, preferably 0.2 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0091] In a preferred embodiment, the sunscreen or daily care composition comprises drometrizole trisiloxane (DTS) in an amount of 0.1 to 10% by weight, preferably 0.2 to 6% by weight, based on the total weight of the sunscreen or daily care composition.

[0092] In a preferred embodiment, the sunscreen or daily care composition comprises: 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate) in an amount of 0.1-8% by weight, preferably 0.5-5% by weight; 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine) in an amount of 0.1 to 7% by weight, preferably 0.5 to 4% by weight; and 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) in an amount of 0.1 to 6% by weight, preferably 0.5 to 4% by weight, Each is included based on the total weight of the sunscreen or daily care composition.

[0093] In a preferred embodiment, the sunscreen or daily care composition comprises at least one organic microparticulated UV filter in an amount of 0.1 to 10% by weight, preferably 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0094] In a preferred embodiment, the sunscreen or daily care composition comprises 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyl Triazone) in an amount of 0.1 to 5% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0095] In a preferred embodiment, the sunscreen or daily care composition comprises 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI Tris-biphenyltriazine) in an amount of 0.1 to 5 wt. %, preferably 0.5 to 4 wt. %, based on the total weight of the sunscreen or daily care composition.

[0096] In a preferred embodiment, the sunscreen or daily care composition further comprises 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamidotriazone or DBT), preferably in an amount of 0.1 to 10% by weight, more preferably 0.2 to 6% by weight, especially 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0097] In a preferred embodiment, the sunscreen or daily care composition comprises DHHB and BEMT in a weight ratio of from 5:1 to 1:4, preferably from 4:1 to 1:3, more preferably from 3:1 to 1:2, in particular from 2:1 to 1:1.5.

[0098] In a preferred embodiment, the sunscreen or daily care composition comprises DHHB and PBSA in a weight ratio of from 5:1 to 1:4, preferably from 4:1 to 1:3, more preferably from 3:1 to 1:2, in particular from 2.5:1 to 1:1.5.

[0099] In a preferred embodiment, the sunscreen or daily care composition comprises DHHB and the sum of BEMT and PBSA in a weight ratio of from 5:1 to 1:6, preferably from 4:1 to 1:5, more preferably from 2:1 to 1:4, in particular from 1.5:1 to 1:2.5.

[0100] In a preferred embodiment, the sunscreen or daily care composition comprises DHHB and EHT in a weight ratio of from 5:1 to 1:4, preferably from 4:1 to 1:3, more preferably from 3:1 to 1:2, in particular from 2.5:1 to 1:1.5.

[0101] In a preferred embodiment, the sunscreen or daily care composition comprises DHHB and MBBT in a weight ratio of from 5:1 to 1:4, preferably from 4:1 to 1:3, more preferably from 3:1 to 1:2, in particular from 2.5:1 to 1:1.5.

[0102] In a preferred embodiment, the sunscreen or daily care composition comprises DHHB and glycerol in a weight ratio of from 3:1 to 1:10, preferably from 2:1 to 1:9, more preferably from 1:1 to 1:9, in particular from 1:2 to 1:7.

[0103] In a preferred embodiment, the sunscreen or daily care composition does not contain 2-cyano-3,3-diphenylprop-2-enoic acid 2-ethylhexyl ester (INCI Octocrylene), (RS)-2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Ethylhexyl Methoxycinnamate), 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Isoamyl p-methoxycinnamate) and / or Homosalate. Preferably, the sunscreen or daily care composition does not contain 2-cyano-3,3-diphenylprop-2-enoic acid 2-ethylhexyl ester (INCI Octocrylene), (RS)-2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Ethylhexyl Methoxycinnamate) and 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Isoamyl p-methoxycinnamate).

[0104] Preferably, the sunscreen or daily care composition does not contain 2-cyano-3,3-diphenylprop-2-enoic acid 2-ethylhexyl ester (INCI Octocrylene), (RS)-2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Ethylhexyl Methoxycinnamate), 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Isoamyl p-methoxycinnamate) and 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate (INCI Homosalate).

[0105] In a preferred embodiment, the sunscreen or daily care composition further comprises a dermatologically acceptable emulsifier, thickener and / or emollient.

[0106] Preferred emulsifiers include: - glucose derivatives, such as cetearyl glucoside, arachidyl glucoside, lauryl glucoside, polyglyceryl-3 methylglucose distearate, methylglucose sesquistearate; - sucrose derivatives, for example sucrose polystearate, sucrose palmitate; - Sorbitol derivatives; - glycerides of fatty acids, for example, glyceryl stearate, glyceryl oleate; - glutamic acid derivatives, for example sodium stearoyl glutamate; - sulfosuccinic acid derivatives, for example disodium cetearyl sulfosuccinate; - phosphoric acid derivatives, for example, potassium cetyl phosphate; - fatty acid esters of polyglyceryl, for example polyglyceryl-3-diisostearate, polyglyceryl-2-dipolyhydroxystearate Examples include:

[0107] Preferred emollients include: - esters of linear or branched fatty acids with linear or branched fatty alcohols, such as, for example, propylheptyl caprylate, coco-caprylate, isopropyl myristate, ethylhexyl palmitate; Esters of aromatic carboxylic acids with linear or branched fatty alcohols, for example C 12 ~C 15 -Alkyl benzoates, ethylhexyl benzoate, phenethyl benzoate; - dicarboxylic acid esters with linear or branched alcohols, for example dibutyl adipate, dicaprylyl carbonate, diisopropyl sebacate; - esters of hydroxycarboxylic acids with linear or branched fatty alcohols; - esters of linear or branched fatty acids with polyhydric alcohols, for example di(caprylic / capric)butylene glycol; - C6~C 18Mono-, di-, and triglycerides based on fatty acids, such as caprylic / capric triglyceride, cocoglyceride; Guerbet alcohols, for example octyldodecynol; - Hydrocarbons, for example hydrogenated polyisobutene, mineral oil, squalene, isohexadecane; - ethers, for example dicaprylyl ether; - Silicone derivatives (organo-modified polysiloxanes), e.g. dimethylpolysiloxane Examples include:

[0108] Preferred thickeners include: - fatty alcohols, such as cetyl alcohol, cetearyl alcohol, behenyl alcohol, stearyl alcohol; - fatty acids, for example stearic acid; - fatty acid esters, for example myristyl stearate; - C18~38 alkyl hydroxystearoyl - waxes, such as beeswax, carnauba wax, microcrystalline wax, ceresin, ozokerite, Oryza Sativa and rice bran wax; - polysaccharides or derivatives, such as xanthan gum, guar gum, agar gum, alginates, gellan gum, carraghenan, tara gum; - silicate derivatives, for example magnesium silicate; Cellulose derivatives, such as hydroxypropyl cellulose Examples include:

[0109] In one embodiment, the sunscreen or daily care composition further comprises feel enhancers, adjuvants, preservatives and / or fragrances.

[0110] Preferred feel enhancers include: - Silica; - Mica; - starch derivatives, such as Al starch octenylsuccinate, tapioca starch, rice (Oryza sativa) starch, corn (Zea mays) (corn) starch; - Dimethicone derivatives; - Boron nitride; - Perlite Examples include:

[0111] Preferred water retention agents include: - 1,2-pentanediol; - 1,2-hexanediol; - 1,2 octanediol; - 1,2-decanediol; - 2-Methyl-1,3-propanediol Examples include:

[0112] Preferred adjuvants include: - Tocopherol derivatives; - Retinol derivatives; - Ascorbic acid derivatives; - Bisabolol; - Allantoin; - Panthenol; - Chelating agents (EDTA, EDDS, EGTA, phytic acid, piroctone olamine); - Ethylhexylglycerin; - Hydroxyacetophenone; - Caprylhydroxymic acid; - Propellants, for example, propane, butane, isobutene, dimethyl ether; - styrene / PVP or styrene / acrylamide copolymers; - insect repellents, e.g. butyl acetylaminopropionate Examples include:

[0113] Preferred preservatives include: - benzyl alcohol; - Zingerone Examples include:

[0114] Preferred fragrances are limonene, citral, linalool, α-isomethyl ionone, geraniol, citronellol, 2-isobutyl-4-hydroxy-4-methyltetrahydropyran, 2-tert-pentylcyclohexyl acetate, 3-methyl-5-phenyl-1-pentanol, 7-acetyl-1,1,3,4,4,6-hexamethyltetralin, adipic acid diester, α-amyl cinnamaldehyde, α-methyl ionone, amyl C butylphenyl methylpropional cinnamal (amyl C butylphenyl methylpropional cinnamal). butylphenylmethylpropionalcinnamal, amyl salicylate, amyl cinnamyl alcohol, anise alcohol, benzoin, benzyl alcohol, benzyl benzoate, benzyl cinnamate, benzyl salicylate, bergamot oil, bitter orange oil, butylphenylmethylpropioal, cardamom oil, cedrol, cinnamal, cinnamyl alcohol, citronnellylmethylcrotonate, lemon oil, coumarin, diethyl succinate, ethyl linalool, eugenol, evernia furfuracea extract, evernia prunastri extract, farensol, guaiac wood oil, hexyl cinnamal, hexylcalicylate, hydroxycitronellal, lavender oil, lemon oil, linalylacetate, mandarin oil, menthyl PCA, methylheptenone, nutmeg oil, rosemary oil, sweet orange oil, terpineol, tonka bean oil, triethyl citrate, vanillin and combinations thereof.

[0115] In relation to the above preferred embodiments, it is to be understood that when the sunscreen or daily care composition comprises two or more additives (e.g. emulsifiers, emollients, thickeners, feel enhancers, adjuvants, preservatives, fragrances), combinations of the above defined additives are also part of the present invention.

[0116] In connection with the above preferred and particularly preferred embodiments, it is to be understood that the sunscreen or daily care composition may further comprise water.

[0117] It is to be understood that when water is present in the sunscreen or daily care composition, it is preferably present in an amount of more than 5% by weight based on the total weight of the composition.Furthermore, it is to be understood that when water is present in the sunscreen or daily care composition, the sunscreen or daily care composition can be an oil-in-water emulsion (O / W emulsion), a water-in-oil emulsion (W / O emulsion), a gel cream, or an oil-in-gel composition.

[0118] In one embodiment of the present invention, the sunscreen or daily care composition may be provided in various forms, such as a gel, cream, oil, lotion or sprayable product.

[0119] The sunscreen and daily care compositions outlined above are particularly suitable for sensitive skin.

[0120] Further disclosed is the use of a sunscreen or daily care composition comprising 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyl triazine) dispersed in a polyglycerol monoalkyl ester to increase the compatibility of the sunscreen or daily composition with the skin microflora. It is understood that the preferred embodiments defined above also apply to the present disclosure.

[0121] Further disclosed is a sunscreen or daily care composition comprising 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyl triazine) for use in a method for increasing the compatibility of the sunscreen or daily composition with the skin microflora, wherein the 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyl triazine) is dispersed in a polyglycerol monoalkyl ester. It is understood that the preferred embodiments defined above also apply to the present disclosure.

[0122] The present invention further relates to a sunscreen or daily care composition comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, for use in a method for increasing the compatibility of the sunscreen or daily composition with the skin microflora, preferably the human skin microflora. It is to be understood that the above-mentioned embodiments of the use aspect of the sunscreen or daily care composition are also applicable to this aspect, in particular with regard to the microorganisms, the at least one additional UVB filter, the at least one micronized UV filter, the at least one additional UVA filter, further ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratios in the sunscreen or daily care composition.

[0123] The present invention further relates to a method for increasing the compatibility of a sunscreen or daily composition with the skin microflora, preferably with the human skin microflora, comprising the step of mixing a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, with at least one other dermatologically acceptable ingredient.

[0124] It is to be understood that the above-mentioned embodiments of the use aspect of the sunscreen or daily care composition are also applicable to this aspect, in particular with regard to the microorganisms, the at least one additional UVB filter, the at least one micronized UV filter, the at least one additional UVA filter, further ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratios in the sunscreen or daily care composition.

[0125] Preferably, the UV filters selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof are mixed with at least one dermatologically acceptable emulsifier, thickener, emollient and / or water.

[0126] The present invention further relates to the use of a UV screening agent selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof in the manufacture of a sunscreen or daily care composition having increased compatibility with the skin microflora, preferably the human skin microflora. It is to be understood that the above-mentioned embodiments of the use aspect of the sunscreen or daily care composition are also applicable to this aspect, in particular with regard to the microorganisms, the at least one additional UVB filter, the at least one micronized UV filter, the at least one additional UVA filter, further ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratios in the sunscreen or daily care composition.

[0127] As mentioned above, the present invention relates in a second aspect to a sunscreen or daily care composition comprising: 0.1 to 10% by weight, preferably 0.5 to 5% by weight, of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoyl hexyl benzoate), 0.1 to 8% by weight, preferably 0.5 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 5% by weight, preferably 0.5 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), 0.1 to 5% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0 to 10% by weight, preferably 0.1 to 5% by weight, of 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 3 to 15% by weight, preferably 5 to 10% by weight, of glycerol, Each based on the total weight of the sunscreen or daily care composition; It further relates to a sunscreen or daily care composition which does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI isoamyl p-methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), zinc oxide and mixtures thereof.

[0128] In a preferred embodiment, 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decylglucoside).

[0129] In a preferred embodiment, the sunscreen or daily care composition comprises at least one additional organic microparticulated UV filter, preferably selected from the group consisting of 5,6,5',6'-tetraphenyl-3-3'-(1,4-phenylene)bis(1,2,4-triazine) (INCI phenylenebis-diphenyltriazine), 1,1'-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]methanone (INCI bis-(diethylaminohydroxybenzoylbenzoyl)piperazine). In this context, it is to be understood that the at least one additional organic microparticulated UV filter may be any organic microparticulated UV filter known in the art, other than 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol).

[0130] In a preferred embodiment, the at least one additional organic particulate UV filter is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI Decylglucoside).

[0131] In a preferred embodiment, at least one additional organic microparticulated UV filter is dispersed in the polyglycerol monoalkyl ester.

[0132] In a preferred embodiment, 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine) are not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decylglucoside).

[0133] In a preferred embodiment, 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine) are dispersed in a polyglycerol monoalkyl ester.

[0134] Preferably, the polyglycerol monoalkyl ester is selected from the group consisting of decaglyceryl caprate, decaglyceryl monolaurate, decaglyceryl myristate, decaglyceryl oleate, decaglyceryl stearate, decaglyceryl isostearate, hexaglyceryl caprate, hexaglyceryl laurate, hexaglyceryl myristate, hexaglyceryl oleate, hexaglyceryl stearate, hexaglyceryl isostearate, pentaglyceryl caprate, pentaglyceryl laurate, pentaglyceryl myristate, pentaglyceryl oleate, pentaglyceryl stearate, pentaglyceryl isostearate and mixtures thereof, more preferably, the at least one polyglycerol monoalkyl ester is decaglyceryl monolaurate (INCI Polyglyceryl-10 Laurate).

[0135] In a preferred embodiment, the sunscreen or daily care composition comprises 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) dispersed in a polyglycerol monoalkyl ester and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine) dispersed in a polyglycerol monoalkyl ester.

[0136] It should be understood that the above-mentioned embodiments of the use of the sunscreen or daily care composition are also applicable to the second aspect, in particular with regard to the at least one additional UVB filter, at least one micronized UV filter, at least one additional UVA filter, further ingredients (such as emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratio in the sunscreen or daily care composition.Further preferred embodiments of the sunscreen or daily care composition of the present invention are disclosed below.

[0137] Preferably, the sunscreen or daily care composition of the invention has no adverse effect on the microflora and is therefore suitable for any skin type. The sunscreen or daily care composition of the invention is particularly suitable for sensitive skin.

[0138] The sunscreen or daily care composition can be administered to any skin type, even sensitive skin.

[0139] In a particularly preferred embodiment, the sunscreen or daily care composition comprises 0.1 to 6% by weight, preferably 0.4 to 5% by weight, of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoyl hexyl benzoate), 0.1 to 6% by weight, preferably 0.4 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 4% by weight, preferably 0.4 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), 0.1 to 4% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0 to 6% by weight, preferably 0.1 to 5% by weight, of 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 3 to 8% by weight, preferably 5 to 8% by weight, of glycerol, Each based on the total weight of the sunscreen or daily care composition; Furthermore, the sunscreen or daily care composition does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI isoamyl p-methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), homosalate, zinc oxide and mixtures thereof.

[0140] In a preferred embodiment, the sunscreen or daily care composition comprises sodium stearoyl glutamate in an amount of 0.1-2% by weight, preferably 1-2% by weight or 0.3-1% by weight, in particular 0.2-1% by weight, based on the total weight of the sunscreen or daily care composition.

[0141] In a preferred embodiment, the sunscreen or daily care composition comprises a monoester of stearic acid and glycerin (e.g., glyceryl stearate SE) in an amount of 1 to 4% by weight, preferably 1.5 to 3% by weight, based on the total weight of the sunscreen or daily care composition.

[0142] In a preferred embodiment, the sunscreen or daily care composition does not contain a zinc derivative compound (having the meanings given above).

[0143] In a preferred embodiment, the sunscreen or daily care composition does not contain a zinc salt. In a particularly preferred embodiment, the sunscreen or daily care composition does not contain a zinc salt of pyrrolidone carboxylic acid.

[0144] In a preferred embodiment, the sunscreen or daily care composition is paraben-free.

[0145] In a preferred embodiment, the sunscreen or daily care composition does not contain 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate (INCI Homosalate).

[0146] In a preferred embodiment, the sunscreen or daily care composition does not contain PVP (polyvinylpyrrolidone) polymers and VP (vinylpyrrolidone) derivatives such as vinylpyrrolidone / hexadecene copolymer, VP / eicosene copolymer, triacontanyl PVP.

[0147] In a preferred embodiment, the sunscreen or daily care composition does not contain acrylic acid based polymers, such as compounds including but not limited to INCI Carbomer, C10 / 30 Alkyl Acrylate Crosspolymer.

[0148] In a preferred embodiment, the sunscreen or daily care composition does not contain ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI Ethylhexyl Methoxycinnamate), 3-Methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Isoamyl p-Methoxycinnamate), Ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI Octocrylene) and Zinc Oxide.

[0149] In a preferred embodiment, the sunscreen or daily care composition comprises: 0.1 to 10% by weight, preferably 0.5 to 5% by weight, of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoyl hexyl benzoate), 0.1 to 8% by weight, preferably 0.5 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 5% by weight, preferably 0.5 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), 0.1 to 5% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0.1 to 10% by weight, preferably 0.1 to 5% by weight, of 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 3 to 15% by weight, preferably 5 to 10% by weight, of glycerol, Each based on the total weight of the sunscreen or daily care composition; Furthermore, the sunscreen or daily care composition does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI isoamyl p-methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), zinc oxide and mixtures thereof.

[0150] In a particularly preferred embodiment, the sunscreen or daily care composition comprises 0.1 to 6% by weight, preferably 0.4 to 5% by weight, of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoyl hexyl benzoate), 0.1 to 6% by weight, preferably 0.4 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 4% by weight, preferably 0.4 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine) and 0.1 to 4% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0.1 to 6% by weight, preferably 0.1 to 5% by weight, of 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol); 3 to 8% by weight, preferably 5 to 8% by weight, of glycerol, Each based on the total weight of the sunscreen or daily care composition; Furthermore, the sunscreen or daily care composition does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI isoamyl p-methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate (INCI homosalate), zinc oxide and mixtures thereof.

[0151] In a preferred embodiment, 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decylglucoside).

[0152] Preferably, 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) is dispersed in the polyglycerol monoalkyl ester.

[0153] Preferably, the polyglycerol monoalkyl ester is selected from the group consisting of decaglyceryl caprate, decaglyceryl monolaurate, decaglyceryl myristate, decaglyceryl oleate, decaglyceryl stearate, decaglyceryl isostearate, hexaglyceryl caprate, hexaglyceryl laurate, hexaglyceryl myristate, hexaglyceryl oleate, hexaglyceryl stearate, hexaglyceryl isostearate, pentaglyceryl caprate, pentaglyceryl laurate, pentaglyceryl myristate, pentaglyceryl oleate, pentaglyceryl stearate, pentaglyceryl isostearate and mixtures thereof, more preferably, the at least one polyglycerol monoalkyl ester is decaglyceryl monolaurate (INCI Polyglyceryl-10 Laurate).

[0154] In a particularly preferred embodiment, the sunscreen or daily care composition comprises 0.1 to 6% by weight, preferably 0.4 to 5% by weight, of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoyl hexyl benzoate), 0.1 to 6% by weight, preferably 0.4 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 4% by weight, preferably 0.4 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), 0.1 to 4% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0.1 to 6% by weight, preferably 0.1 to 5% by weight, of 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 3 to 8% by weight, preferably 5 to 8% by weight, of glycerol, Each based on the total weight of the sunscreen or daily care composition; Furthermore, the sunscreen or daily care composition does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI isoamyl p-methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), zinc oxide and mixtures thereof, and 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) does not contain (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decyl glucoside).

[0155] In a preferred embodiment, the sunscreen or daily care composition comprises C2 to C 12 -Alkanediols, preferably 1,2-C 12 -Alkanediol or 1,3-C2-C 12 -alkanediols, more preferably 1,2-C 10-Alkanediol or 1,3-C2-C 10 -Alkanediols, especially 1,2-C 10 Preferably, the sunscreen or daily care composition further comprises a C2-C8 alkanediol or a 1,2-C2-C8 alkanediol. 12 -alkanediol in an amount of 0.5 to 10% by weight, more preferably 1 to 8% by weight, based on the total weight of the sunscreen or daily care composition.

[0156] In a preferred embodiment, the sunscreen or daily care composition further comprises glycerol, preferably in an amount of 1-10% by weight, more preferably 2-8% by weight or 4-10% by weight, especially 3-7% by weight or 4-8% by weight, based on the total weight of the sunscreen or daily care composition.

[0157] In a preferred embodiment, the sunscreen or daily care composition comprises DHHB and glycerol in a weight ratio of from 3:1 to 1:10, preferably from 2:1 to 1:9, more preferably from 1:1 to 1:9, in particular from 1:2 to 1:7.

[0158] In a preferred embodiment, the SPF value of the sunscreen or daily care is 6 to 50+ (according to EC recommendations). The SPF and UVA-PF can be determined exemplarily by simulation calculations using the BASF Sunscreen Simulator (https: / / sunscreensimulator.basf.com / ) or in vitro. A suitable in vitro method can be carried out as follows:

[0159] The in vitro SPF and in vitro UVA-PF were determined according to ISO 24443, which is based on the evaluation of the UV transmittance through a thin sunscreen sample stretched on a rough substrate SB6 PMMA plate (roughness 4-5 μm, area 4.8 × 4.8 cm) from Helioscreen, Paris. The tested sunscreen formulations were applied at 1.2 mg / cm. 2The formulation was spread by hand as evenly as possible on the plate. The plate with the formulation was stored at room temperature in the dark for 30 minutes before measurement.

[0160] measurement: Process 1 Prior to UV irradiation, in vitro transmittance measurements were performed at 1 nm intervals from 290 to 400 nm using a Labsphere UV Transmittance Analyzer UV 2000S. Initial UV transmittance spectra were obtained and the in vitro SPF value before irradiation was calculated (average SPF of all 15 values ​​(from 5 measurements per plate on 3 plates)).

[0161] Process 2 A numerical adjustment of the initial UV spectrum was performed using the factor “c” as specified in ISO 24443 to calculate the in vitro UVA-PF before irradiation.

[0162] Process 3 The amount of UV irradiation to the formulation using the Atlas Suntest CPS+ Solar simulator was calculated using UV Dose D as specified in ISO 24443.

[0163] Process 4 The in vitro transmittance after UV exposure was measured, and the UV transmission spectrum after irradiation was obtained. The in vitro SPF value after irradiation was determined (average of 15 values ​​from 5 measurements per plate on 3 plates).

[0164] Process 5 A numerical adjustment of the UV spectrum after irradiation was performed using the same coefficient "c" (determined in step 2). The in vitro UVA-PF after UV exposure was calculated.

[0165] In connection with the above preferred and particularly preferred embodiments, it is to be understood that the sunscreen or daily care composition may further comprise water.

[0166] It should be understood that when water is present in the sunscreen or daily care composition, it is preferably present in an amount greater than 5% by weight based on the total weight of the composition. The sunscreen or daily care composition may be an oil-in-water emulsion (O / W emulsion), a water-in-oil emulsion (W / O emulsion), a gel-cream or an oil-in-gel composition.

[0167] In one embodiment of the present invention, the sunscreen or daily care composition can be provided in various forms, such as a gel, cream, oil, lotion, or a sprayable product (in an aerosol container or not).

[0168] As mentioned above, the present invention relates in a third aspect to the use of a composition (A) comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, for producing a sunscreen or daily care composition compatible with the skin microflora.

[0169] "Compatible with the skin microbiota" refers to a sunscreen or daily care composition (e.g. comprising a DHHB-containing composition (A)) having at least the same effect on the skin microbiota when compared to a strictly identical sunscreen or daily care composition but without DHHB. This can be determined exemplarily by the methods outlined above, detecting the number of skin microbiota microorganisms, preferably Staphylococcus epidermidis, for example over a 24-hour period. Preferably, the sunscreen or daily care composition according to the invention further provides increased compatibility with the skin microbiota. What is meant by "increasing the compatibility of the sunscreen or daily composition with the skin microbiota" has already been outlined in more detail above.

[0170] It should be understood that the above-mentioned embodiments of the use of the sunscreen or daily care composition are also applicable to the third aspect, in particular with regard to the microorganisms, at least one additional UVB filter, at least one organic microparticulated UV filter, at least one additional UVA filter, further ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratio in the sunscreen or daily care composition. Further preferred embodiments of the sunscreen or daily care composition of the present invention are disclosed below.

[0171] In a preferred embodiment, composition (A) comprises hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate).

[0172] In a preferred embodiment, composition (A) comprises a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate), terephthalidenedicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof.

[0173] In a preferred embodiment, the sunscreen or daily care composition comprises 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate) and further 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine) and / or 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid).

[0174] In a preferred embodiment, the sunscreen or daily care composition comprises hexyl 2-[4-(diethylamino)-2 hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate) in an amount of 0.1 to 10% by weight, preferably 0.2 to 9% by weight, more preferably 0.3 to 8% by weight, even more preferably 0.4 to 6% by weight and in particular 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0175] In a preferred embodiment, the sunscreen or daily care composition comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine) in an amount of 0.1 to 10% by weight, preferably 0.3 to 6% by weight, in particular 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0176] In a preferred embodiment, the sunscreen or daily care composition comprises 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) in an amount of 0.1 to 8% by weight, preferably 0.3 to 6% by weight, in particular 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0177] In a preferred embodiment, composition (A) comprises 2-[4-(diethylamino)-2 hydroxybenzoyl] hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate) in an amount of 70-100% by weight, preferably 80-100% by weight, more preferably 90-100% by weight, especially 95-100% by weight, based on the total weight of composition (A). In a particular embodiment, composition (A) consists of 2-[4-(diethylamino)-2 hydroxybenzoyl] hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate).

[0178] In a preferred embodiment, composition (A) comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine) in an amount of 70-100% by weight, preferably 80-100% by weight, more preferably 90-100% by weight, especially 95-100% by weight, based on the total weight of composition (A). In a particular embodiment, composition (A) consists of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine).

[0179] In a preferred embodiment, composition (A) comprises phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) in an amount of 70-100% by weight, preferably 80-100% by weight, more preferably 90-100% by weight, especially 95-100% by weight, based on the total weight of composition (A). In a particular embodiment, composition (A) consists of phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid).

[0180] In a preferred embodiment, composition (A) comprises terephthalylidene dicamphorsulfonic acid (TDSA) in an amount of 70 to 100% by weight, preferably 80 to 100% by weight, more preferably 90 to 100% by weight, and especially 95 to 100% by weight, based on the total weight of composition (A). In a particular embodiment, composition (A) consists of terephthalylidene dicamphorsulfonic acid (TDSA).

[0181] In a preferred embodiment, composition (A) comprises drometrizole trisiloxane (DTS) in an amount of 70 to 100% by weight, preferably 80 to 100% by weight, more preferably 90 to 100% by weight, especially 95 to 100% by weight, based on the total weight of composition (A). In a particular embodiment, composition (A) consists of drometrizole trisiloxane (DTS).

[0182] In a preferred embodiment, the sunscreen or daily care composition is produced by adding composition (A) to the oil phase. Preferably, composition (A) (preferably comprising 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate)) is added under stirring. The oil phase may contain any suitable additional UV screening agent known in the art. Particularly suitable UV filters that may be present in the oil phase are 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI ethylhexyl triazone) and mixtures thereof. Preferably, the composition comprising composition (A) (preferably comprising 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate)) and an oil phase is mixed with at least one aqueous phase. Another suitable additional UV filter may be present in the aqueous phase. Particularly suitable UV filters which may be present in the aqueous phase are 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), terephthalylidene dicamphorsulfonic acid (TDSA).

[0183] In a preferred embodiment, the sunscreen or daily care composition is produced by adding composition (A) to the oil phase. Preferably, composition (A) (preferably containing drometrizole trisiloxane) is added under stirring. The oil phase may contain any suitable additional UV filter known in the art. Particularly suitable UV filters that may be present in the oil phase are 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI ethylhexyl triazone) and mixtures thereof. Preferably, the composition (A) (preferably comprising drometrizole trisiloxane) and the oil phase is mixed with at least one water phase. In the water phase, another suitable additional UV filter may be present. Particularly suitable UV filters that may be present in the water phase are 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA).

[0184] In a preferred embodiment, the sunscreen or daily care composition is produced by adding composition (A) to an aqueous phase. Preferably, composition (A), preferably comprising 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), is added under stirring.

[0185] In a preferred embodiment, the sunscreen or daily care composition is produced by adding composition (A) to an aqueous phase. Preferably, composition (A) (preferably comprising terephthalylidene dicamphorsulfonic acid (TDSA)) is added under stirring. Preferably, the composition comprising composition (A) (preferably comprising terephthalylidene dicamphorsulfonic acid (TDSA)) is mixed with at least one lipophilic phase. Another suitable additional UV screening agent may be present in the lipophilic phase. Particularly suitable UV filters which may be present in the lipophilic phase are 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoylhexyl benzoate), 4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI ethylhexyl triazone).

[0186] The sunscreen or daily care composition comprises typical sunscreen or daily care composition ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances). Preferably, the sunscreen or daily care composition comprises glycerol. Preferably, the sunscreen or daily care composition comprises glycerol in an amount of 1-10% by weight, more preferably 2-8% by weight or 4-10% by weight, especially 5-8% by weight, based on the total weight of the sunscreen or daily care composition.

[0187] In a preferred embodiment, the sunscreen or daily care has an SPF value between 6 and 50+ (according to EC recommendations), the SPF being determined in vitro, more preferably by the method outlined below (by way of examples).

[0188] The present invention further relates to a composition (A) comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, for use in a method for producing a sunscreen or daily care composition compatible with the skin microflora, preferably the human skin microflora. It is to be understood that the above-mentioned embodiments of the use aspects of the sunscreen or daily care composition and of the use aspects of composition (A) are also applicable to this aspect, in particular with regard to the microorganisms, the at least one additional UVB filter, the at least one organic microparticulated UV filter, the at least one additional UVA filter, further ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratios in the sunscreen or daily care composition.

[0189] The present invention further relates to a method for producing a sunscreen or daily care composition compatible with the skin microflora, preferably the human skin microflora, comprising the step of mixing a composition (A) comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, and at least one other dermatologically acceptable ingredient.

[0190] It is to be understood that the above-mentioned embodiments of the use aspects of the sunscreen or daily care composition and of the use aspects of composition (A) are also applicable to this aspect, in particular with regard to the microorganisms, the at least one additional UVB filter, the at least one organic microparticulated UV filter, the at least one additional UVA filter, further ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratios in the sunscreen or daily care composition.

[0191] Preferably, composition (A) is mixed with at least one dermatologically acceptable emulsifier, thickener and / or emollient.

[0192] The present invention further relates to the use of a composition (A) comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid), terephthalidenedicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS) and mixtures thereof, in the manufacture of a sunscreen or daily care composition having increased compatibility with the skin microflora, preferably the human skin microflora. It is to be understood that the above-mentioned embodiments of the use aspects of the sunscreen or daily care composition and of the use aspects of composition (A) are also applicable to this aspect, in particular with regard to the microorganisms, the at least one additional UVB filter, the at least one organic microparticulated UV filter, the at least one additional UVA filter, further ingredients (e.g. emulsifiers, thickeners, emollients, feel enhancers, adjuvants, preservatives and / or fragrances) and their amount / weight ratios in the sunscreen or daily care composition.

[0193] The present invention further relates to the following: 1. A sunscreen or daily care composition comprising a UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid) and mixtures thereof, for use in a method for increasing the compatibility of the sunscreen or daily composition with the skin microflora.

[0194] 2. A sunscreen or daily care composition according to item 1, comprising 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate) and optionally further comprising 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine) and / or 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid).

[0195] 3. A UV filter selected from the group consisting of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexylbenzoate (INCI diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI phenylbenzimidazole sulfonic acid) and mixtures thereof is added to the sunscreen or daily care composition and to the antibacterial properties of Propionibacterium acnes, Propionibacterium granulosum, Propionibacterium avidum on the skin. avidum, Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus hominis, Staphylococcus xylosus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus saccharolyticus, Staphylococcus conii, Staphylococcus auricularis, Micrococcus luteus luteus, Corynebacterium minutissimum, Corynebacterium jeikeium, Corynebacterium tuberculostearicumtuberculostearicum, Corynebacterium fastidiosum, Corynebacterium simulans, Corynebacterium amycolatum, Corynebacterium xerosis, Streptococcus mitis, Streptococcus sanguinis, Streptococcus oralis, Brevibacterium spp., Pseudomonas spp. and mixtures thereof, preferably Staphylococcus epidermidis. and / or increasing compatibility with a bacterial population selected from the group consisting of: 3. The sunscreen or daily care composition according to item 1 or 2, which increases the compatibility of the sunscreen or daily care composition with a fungal population on the skin selected from the group consisting of Malassezia furfur, Malassezia restricta, Malassezia globosa, Candida spp. and mixtures thereof.

[0196] 4. Preferably, 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyl Triazone), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamido Triazone or DBT), dimethicone diethyl benzyl malonate (INCI 4. The sunscreen or daily care composition according to any one of items 1 to 3, further comprising at least one additional UVB screening agent selected from the group consisting of polysilixone-15) and mixtures thereof, in particular selected from the group consisting of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyl Triazone or EHT), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamidotriazone or DBT) and mixtures thereof.

[0197] 5. 2,2'-Methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol), 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 5,6,5',6'-tetraphenyl-3-3'-(1,4-phenylene)bis(1,2,4-triazine) (INCI phenylenebis-diphenyltriazine), 1,1'-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]methanone (INCI 5. The sunscreen or daily care composition according to any one of items 1 to 4, further comprising at least one organic microparticulated UV filter selected from the group consisting of 2,2'-methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazol-2-yl)phenol] (INCI Methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI Tris-biphenyltriazine).

[0198] 6. The sunscreen or daily care composition according to item 5, wherein the at least one organic microparticulated UV filter is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI decylglucoside) and / or the at least one organic microparticulated UV filter is dispersed in a polyglycerol monoalkyl ester.

[0199] 7. Sunscreen or daily care composition according to any one of items 1 to 6, further comprising at least one additional UVA screening agent, preferably selected from the group consisting of disodium phenyldibenzimidazole tetrasulfonate, 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butyl Methoxydibenzoylmethane) and mixtures thereof, in particular 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butyl Methoxydibenzoylmethane).

[0200] 8. The sunscreen or daily care composition according to any one of items 1 to 7, wherein the sunscreen or daily care composition does not contain zinc oxide (ZnO).

[0201] 9. A sunscreen or daily care composition according to any one of items 1 to 8, comprising hexyl 2-[4-(diethylamino)-2 hydroxybenzoyl]benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate) in an amount of 0.1 to 10% by weight, preferably 0.5 to 8% by weight, in particular 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0202] 10. 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine) in an amount of 0.1 to 7% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition, and / or 10. The sunscreen or daily care composition according to any one of items 1 to 9, comprising 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) in an amount of 0.1 to 6 wt.-%, preferably 0.5 to 4 wt.-%, based on the total weight of the sunscreen or daily care composition.

[0203] 11. The sunscreen or daily care composition according to any one of items 1 to 10, comprising at least one organic microparticulated UV filter in an amount of 0.1 to 10% by weight, preferably 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

[0204] 12. A sunscreen or daily care composition according to any one of items 1 to 11, comprising 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyltriazone) in an amount of 0.1 to 5% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

[0205] 13. The sunscreen or daily care composition according to any one of items 1 to 12, further comprising a dermatologically acceptable emulsifier, thickener and / or emollient.

[0206] 14. A sunscreen or daily care composition according to any one of items 1 to 13, which does not contain 2-cyano-3,3-diphenylprop-2-enoic acid 2-ethylhexyl ester (INCI octocrylene), (RS)-2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI ethylhexyl methoxycinnamate) and / or 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI isoamyl p-methoxycinnamate).

[0207] 15. A sunscreen or daily care composition comprising: 0.1 to 10% by weight, preferably 0.5 to 5% by weight, of 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoyl hexyl benzoate), 0.1 to 8% by weight, preferably 0.5 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 5% by weight, preferably 0.5 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), 0.1 to 5% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0 to 10% by weight, preferably 0.1 to 5% by weight, of 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 3 to 15% by weight, preferably 5 to 10% by weight, of glycerol, Each based on the total weight of the sunscreen or daily care composition; Furthermore, the sunscreen or daily care composition does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI ethylhexyl methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI p_isoamyl methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI octocrylene), zinc oxide and mixtures thereof.

[0208] 16. Composition (A), comprising 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate (INCI diethylaminohydroxybenzoylhexyl benzoate), for use in a method for producing a sunscreen or daily care composition compatible with the skin microbiome.

[0209] 17. Composition (A) according to item 16, wherein the sunscreen or daily care composition further comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine) and / or 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid). EXAMPLES

[0210] The present invention is further illustrated by the following examples.

[0211] SPF rating SPF values ​​were calculated according to the BASF sunscreen simulator ( https: / / sunscreensimulator.basf.com / ).

[0212] Determination of antimicrobial activity (AA) to assess microbial compatibility Bacteria: Staphylococcus epidermidis, Micrococcus luteus, Corynebacterium jeikeium and Malassezia furfur (typical representatives of the human skin flora) were used.

[0213] Inoculum: Second subcultures of S. epidermidis and Micrococcus luteus on tryptic soy agar were suspended in tryptic soy broth and incubated overnight (overnight culture, 24 h at 36°C).

[0214] A second subculture of Corynebacterium jeikeium on tryptic soy agar was suspended in tryptic soy broth containing 1.0% polysorbate 80 and incubated overnight (24 h) at 36°C.

[0215] A second subculture of Malassezia furfur on medium 472 agar was suspended in medium 472 broth and incubated at 30°C for 6 days (medium 472 = 472.PITYROSPORUM MEDIUM (no agar) from DSMZ).

[0216] Test Design: Each formulation tested was spiked with a microbial suspension (eg, a dilution of an overnight culture of S. epidermidis in sodium chloride) (T0).

[0217] Staphylococcus epidermidis and Micrococcus luteus: After 2, 4 and / or 24 hours of contact, each sample was spread onto the surface of a tryptone soy agar plate and incubated at 36° C. for 2 days before microbial enumeration.

[0218] Corynebacterium jeikeium: After 2, 4 and / or 24 hours of contact, each sample was spread onto the surface of tryptone soy agar plates containing 1.0% polysorbate 80 and incubated at 36° C. for 2 days before microbial enumeration.

[0219] Malassezia furfur: After 2, 4 and / or 24 hours of contact, each sample was spread on the surface of a medium 472 agar plate and incubated at 30° C. for 6 days before the microorganisms were counted (medium 472=472.PITYROSPORUM MEDIUM from DSMZ).

[0220] evaluation: For all test conditions, the total number of colony forming units (cfu / mL) on each agar plate is counted.

[0221] formulation: The tested UV filters were added in an effective amount of 1% (formulations 1-14 and 16-18, Tables 2a-2d). Placebo emulsion without UV screening agent (Formulation 15, Tables 2a-2c) Combination of UV blocking agents (formulations 19-21, Table 3) Combination of UV blocking agents (formulations 22 to 24, Table 4) Combination of UV blocking agents (formulations 25 to 27, Table 5) Combination of UV screening agents (formulations 28-30, Table 6) Combination of UV blocking agents (formulations 31 to 34, Table 7)

[0222] The antibacterial activity (AA) for evaluating microbial compatibility shown in Tables 2a to 2d was classified into the following 10 groups.

[0223] Groups 2_1 to 2_5 (values ​​after 2 hours of contact): Group 2_1: The number of tested microorganisms (cfu / mL) was 10 5 ~10 6 is in the range of less than Group 2_2: The number of tested microorganisms (cfu / mL) was 10 4 ~10 5 is in the range of less than Group 2_3: The number of tested microorganisms (cfu / mL) was 10 3 ~10 4 is in the range of less than Group 2_4: The number of tested microorganisms (cfu / mL) was 10 2 ~10 3 is in the range of less than Group 2_5: The number of tested microorganisms (cfu / mL) was 10 1 is in the range of less than

[0224] Groups 4_1 to 4_5 (values ​​after 4 hours of contact): Group 4_1: The number of tested microorganisms (cfu / mL) was 10 5 ~10 6 is in the range of less than Group 4_2: The number of tested microorganisms (cfu / mL) was 10 4 ~10 5 is in the range of less than Group 4_3: The number of tested microorganisms (cfu / mL) was 10 3 ~10 4 is in the range of less than Group 4_4: The number of tested microorganisms (cfu / mL) was 10 2 ~10 3 is in the range of less than Group 4_5: The number of tested microorganisms (cfu / mL) was 10 1 is in the range of less than

[0225] Groups 24_1 to 24_5 (values ​​after 24 hours of contact): Group 24_1: The number of tested microorganisms (cfu / mL) was 10 5 ~10 6 is in the range of less than Group 24_2: The number of tested microorganisms (cfu / mL) was 10 4 ~10 5 is in the range of less than Group 24_3: The number of tested microorganisms (cfu / mL) was 10 3 ~10 4 is in the range of less than Group 24_4: Number of tested microorganisms (cfu / mL) was 10 2 ~10 3 is in the range of less than Group 24_5: Number of tested microorganisms (cfu / mL) was 10 1 is in the range of less than

[0226] Formulations 1-18 were prepared as follows: Phase A and part B1 were heated to 80°C. Part B2 was added under stirring and once homogenous part B3 was added under high speed homogenizer (Ultra Turrax type device). Phase A was added to phase B under stirring and homogenized (Ultra Turrax type device). The mixture was cooled under stirring and the pH was adjusted to approximately 6.5 with sodium hydroxide solution.

[0227] [Table 1]

[0228] The antibacterial activity of formulations 1-18 was tested to assess their microbial compatibility. As can be seen from Table 2a, each of the UV filters used has an effect on the population of Staphylococcus epidermidis.

[0229] [Table 2]

[0230] [Table 3]

[0231] Additionally, the antibacterial activity was tested to evaluate the microbial compatibility of formulations 1-3 and 15. As can be seen from Tables 2b and 2c, each of the UV filters used has a positive effect on the populations of Micrococcus luteus and Corynebacterium jeikeium.

[0232] [Table 4]

[0233] [Table 5]

[0234] [Table 6]

[0235] For formulations 19-21, phase A and part B1 were heated to 80°C. Part B2 was added to part B1 under stirring and once homogenous, part B3 was added to B1 / B2 under high speed homogenizer (Ultra Turrax type device). Phase A was added to phase B under stirring and homogenized (Ultra Turrax type device). Pre-prepared phase C was added to the emulsion, which was then cooled under stirring and finally phase D was added below 40°C and the pH was adjusted to above 7 with sodium hydroxide solution.

[0236] [Table 7]

[0237] [Table 8]

[0238] For formulations 22-24, phase A and part B1 were heated to 80° C. Part B2 was added to part B1 under stirring. Phase A was added to phase B under stirring and homogenized (using an Ultra Turrax type device). The previously prepared phase C was added to the emulsion, which was cooled under stirring and finally phase D, if present, was added below 40° C. and the pH was adjusted to >7 with sodium hydroxide solution.

[0239] [Table 9]

[0240] [Table 10]

[0241] As can be seen from the above examples, the present invention provides a screening agent system for sunscreens, for example with SPFs between 10 and 50, which does not have a negative effect on the microflora.

[0242] Further Exemplary Formulations For formulations 25-30, phase A and part B1 were heated to 80°C. Part B2 was added to part B1 under stirring. Phase A was added to phase B under stirring and homogenized (using an Ultra Turrax type device). The previously prepared phase C was added to the emulsion, which was cooled under stirring, phase D, if present, was added and the pH was adjusted to >7 with sodium hydroxide solution.

[0243] [Table 11]

[0244] [Table 12]

[0245] [Table 13]

[0246] [Table 14]

[0247] For formulations 31-34, phases A and B were heated to 80° C. Phase A was added to phase B under stirring and homogenized (using an Ultra Turrax type device). The previously prepared phase C was added to the emulsion, which was cooled under stirring, phase D, if present, was added and the pH was adjusted to >7 with sodium hydroxide solution.

[0248] [Table 15]

[0249]

Table 16

Claims

1. 1. Use of a sunscreen or daily care composition comprising a UV filter selected from the group consisting of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS), and mixtures thereof, to increase the compatibility of said sunscreen or daily care composition with the skin microflora.

2. 2. Use according to claim 1, wherein the sunscreen or daily care composition comprises hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate), optionally further comprising 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), terephthalylidene dicamphorsulfonic acid and / or drometrizole trisiloxane.

3. The sunscreen or daily care composition may further comprise a UV filter selected from the group consisting of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylamino Hydroxybenzoyl Hexyl Benzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol Methoxyphenyl Triazine), 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS), and mixtures thereof, which is effective in preventing the growth of Propionibacterium acnes on the skin. acnes), Propionibacterium granulosum, Propionibacterium avidum, Staphylococcus epidermidis, Staphylococcus saprophyticus, Staphylococcus hominis, Staphylococcus xylosus xylosus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus saccharolyticus, Staphylococcus conii, Staphylococcus auricularis, Micrococcus luteus, Corynebacterium minutissimum minutissimum), Corynebacterium jeikeiumCorynebacterium jeikeium, Corynebacterium tuberculostearicum, Corynebacterium fastidiosum, Corynebacterium simulans, Corynebacterium amycolatum, Corynebacterium xerosis, Streptococcus mitis, Streptococcus sanguinis, Streptococcus sanguinis, Streptococcus oralis, Brevibacterium spp., Pseudomonas spp. and mixtures thereof, preferably Staphylococcus epidermidis; and / or 3. The use according to claim 1 or 2, which increases the compatibility of the sunscreen or daily care composition with a fungal population on the skin selected from the group consisting of Malassezia furfur, Malassezia restricta, Malassezia globosa, Candida spp. and mixtures thereof.

4. The sunscreen or daily care composition preferably comprises 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyltriazone), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamidotriazone or DBT), dimethicone diethylbenzylmalonate (INCI 3. Use according to claim 1 or 2, further comprising at least one additional UVB filter selected from the group consisting of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyltriazone or EHT), 4,4'-[[6-[[4-[[(1,1-dimethylethyl)amino]carbonyl]phenyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-benzoic acid-bis(2-ethylhexyl)ester (INCI Diethylhexylbutamidotriazone or DBT), and mixtures thereof.

5. The sunscreen or daily care composition may comprise 2,2'-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI methylenebis-benzotriazolyltetramethylbutylphenol), 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI tris-biphenyltriazine), 5,6,5',6'-tetraphenyl-3-3'-(1,4-phenylene)bis(1,2,4-triazine) (INCI phenylenebis-diphenyltriazine), 1,1'-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]methanone (INCI 3. Use according to claim 1 or 2, further comprising at least one organic microparticulate UV filter selected from the group consisting of 2,2'-methylenebis[4-(1,1,3,3-tetramethylbutyl)-6-(2H-benzotriazol-2-yl)phenol] (INCI Methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI Tris-biphenyltriazine).

6. 6. The use of claim 5, wherein the at least one organic micronized UV filter is not dispersed in (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (INCI Decylglucoside) and / or the at least one organic micronized UV filter is dispersed in a polyglycerol monoalkyl ester.

7. 3. Use according to claim 1 or 2, wherein the sunscreen or daily care composition further comprises at least one additional UVA filter, preferably selected from the group consisting of disodium phenyldibenzimidazole tetrasulfonate, 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butylmethoxydibenzoylmethane) and mixtures thereof, in particular 1-(4-(1,1-dimethylethyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-dione (INCI Butylmethoxydibenzoylmethane).

8. 3. The use according to claim 1 or 2, wherein the sunscreen or daily care composition does not contain zinc oxide (ZnO).

9. 3. Use according to claim 1 or 2, wherein the sunscreen or daily care composition comprises hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate) in an amount of 0.1 to 10% by weight, preferably 0.5 to 8% by weight, in particular 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

10. the sunscreen or daily care composition comprises 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine) in an amount of 0.1 to 7% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition; and / or 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid) in an amount of 0.1 to 6% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition; and / or terephthalylidene dicamphorsulfonic acid (TDSA) in an amount of 0.1 to 10% by weight, preferably 0.2 to 5% by weight, based on the total weight of the sunscreen or daily care composition; and / or 3. Use according to claim 1 or 2, comprising drometrizole trisiloxane (DTS) in an amount of 0.1 to 10% by weight, preferably 0.2 to 6% by weight, based on the total weight of the sunscreen or daily care composition.

11. 3. Use according to claim 1 or 2, wherein the sunscreen or daily care composition comprises at least one organic micronized UV filter in an amount of 0.1 to 10% by weight, preferably 0.5 to 5% by weight, based on the total weight of the sunscreen or daily care composition.

12. 3. Use according to claim 1 or 2, wherein the sunscreen or daily care composition comprises 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl)ester (INCI Ethylhexyltriazone) in an amount of 0.1 to 5% by weight, preferably 0.5 to 4% by weight, based on the total weight of the sunscreen or daily care composition.

13. 3. The use according to claim 1 or 2, wherein the sunscreen or daily care composition further comprises a dermatologically acceptable emulsifier, thickener and / or emollient.

14. 3. Use according to claim 1 or 2, wherein the sunscreen or daily care composition does not contain 2-cyano-3,3-diphenylprop-2-enoic acid 2-ethylhexyl ester (INCI Octocrylene), (RS)-2-ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Ethylhexyl Methoxycinnamate), 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI Isoamyl p-methoxycinnamate) and / or homosalate.

15. 1. A sunscreen or daily care composition comprising: 0.1 to 10% by weight, preferably 0.5 to 5% by weight, of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate), 0.1 to 8% by weight, preferably 0.5 to 4% by weight, of 2-phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), 0.1 to 5% by weight, preferably 0.5 to 3% by weight, of 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), and 0.1 to 5% by weight, preferably 0.1 to 3% by weight, of 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-benzoic acid-tris(2-ethylhexyl) ester (INCI Ethylhexyl Triazone), 0 to 10% by weight, preferably 0.1 to 5% by weight, of 2,2′-methylenebis[6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol] (INCI Methylenebis-benzotriazolyltetramethylbutylphenol) and / or 2,4,6-tris(biphenyl-4-yl)-1,3,5-triazine (INCI Tris-biphenyltriazine), 3 to 15% by weight, preferably 5 to 10% by weight, of glycerol, each based on the total weight of the sunscreen or daily care composition; Furthermore, the sunscreen or daily care composition does not contain a compound selected from the group consisting of ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylate (INCI Ethylhexyl Methoxycinnamate), 3-methylbutyl(2E)-3-(4-methoxyphenyl)prop-2-enoate (INCI p_Isoamyl Methoxycinnamate), ethylhexyl-2-cyano-3,3-diphenyl-acrylate (INCI Octocrylene), zinc oxide, and mixtures thereof.

16. 1. Use of a composition (A) comprising a UV filter selected from the group consisting of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI Diethylaminohydroxybenzoylhexylbenzoate), 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine), phenyl-3H-benzimidazole-5-sulfonic acid (INCI Phenylbenzimidazole Sulfonic Acid), terephthalylidene dicamphorsulfonic acid (TDSA), drometrizole trisiloxane (DTS), and mixtures thereof, to produce a sunscreen or daily care composition that is compatible with the skin microbiome.

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