Amino acid frosted cleaning composition as well as preparation method and application thereof

Abstract

The invention provides an amino acid frosted cleaning composition as well as a preparation method and application thereof. The amino acid frosted cleaning composition comprises a surfactant, an amino acid composition, a thickening agent, a humectant, an antioxidant, a pH regulator and water, the surfactant is a combination of cocoyl glycinate, cocamidopropyl hydroxy sulfobetaine, sodium cocoyl methyl taurine taurate, sulfonic acid hydroxypropyl ester lauryl glucoside cross-linked polymer sodium and glycolipid. According to the invention, a mild surfactant system with amino acid as a main component is adopted, so that the shampoo has rich and fine foam, quick foaming performance and easy washing performance, and the skin feeling is smooth and soft after washing. In addition, the system contains suspended crystal frosted particles formed by self-assembly of the amino acid composition, the appearance is novel, the better efficacy performance is achieved, and meanwhile the cleaning effect and the use comfort are improved.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of cosmetics, and particularly relates to an amino acid scrubbing cleaning composition and a preparation method and application thereof. BACKGROUND

[0002] Cleaning products are used to remove dirt on the skin or hair, and keep the skin and hair clean. At present, the cleaning products on the cosmetic market are mainly divided into three categories. The first category is anionic surfactants as the main surfactants, such as sodium olefin sulfonate, lauryl polyether sulfate, and amino acid surfactants. The second category is amphoteric surfactants as the main surfactants, such as alkyl amido betaine and sodium acyl taurate. The third category is nonionic surfactants as the main surfactants, such as alkyl polyglucoside. Sodium olefin sulfonate and lauryl polyether sulfate have rich foam, are easy to thicken, and are cheap. At present, the common washing and caring products on the market are mainly prepared by using the anionic surfactants. In addition to having moderate cleaning ability, the cleaning products should also focus on their conditioning effect and mildness. The amino acid surfactants have good rinsing feeling, rich foam, good mildness, and excellent skin feeling after washing, and are thus commonly used in facial cleansers in recent years.

[0003] Surfactants can clean the oil and dirt on the skin and hair, and also remove normal skin lipids. Excessive use of surfactants can cause problems such as dry and tight skin, skin sensitivity and irritation, and damage to the skin barrier. Therefore, the balance between cleaning ability and skin mildness should be maintained when selecting surfactants. Sodium olefin sulfonate and lauryl polyether sulfate commonly used in washing and caring products have too strong degreasing and cleaning ability, and have dry and rough skin feeling after washing, and can also cause excessive skin degreasing, thereby causing eye and skin problems. The skin compatibility of lauryl polyether sulfate is related to the degree of ethoxylation of the fatty alcohol, and thus the skin compatibility and irritation problems, especially the compatibility with the eyes and mucous membranes, should be concerned during use. Although alkyl amido betaine and alkyl polyglucoside have good safety and mildness, their foam performance is relatively weak.

[0004] In recent years, with the popularity of precise skin care, people have more and more demand for functional cleaning products. Products with novel concepts, eye-catching appearance, and technological feeling are easily welcomed by consumers. At present, the cleaning products on the market mainly have liquid or paste in terms of appearance, and some products add scrubbing particles to create a special appearance. The functional cleaning products only have cleaning function, and rarely have other skin care functions. SUMMARY

[0005] In view of the deficiencies of the prior art, the present application provides an amino acid scrubbing cleaning composition and a preparation method and application thereof.

[0006] To achieve the object of the present application, the present application adopts the following technical solutions:

[0007] In a first aspect, the present application provides an amino acid scrub cleaning composition, which comprises a surfactant, an amino acid composition, a thickening agent, a humectant, an antioxidant, a pH regulator and water.

[0008] The surfactant is a combination of cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer and sugar lipid.

[0009] The amino acid scrub cleaning composition of the present application adopts a mild amino acid-based surfactant system. Compared with an amphoteric surfactant and a glycoside-based system, the present system has rich and delicate foam, rapid foaming performance and easy rinsing, and the skin feels smooth and soft after washing. The cocoyl glycinate is a kind of amino acid surfactant with foam boosting and stabilizing effect, which brings rich and delicate foam to the system. The cocamidopropyl hydroxysultaine brings superior foam performance and mildness to the system, which can reduce the irritation of other surfactants in the formula to the skin, mucous membrane and eyes. The sodium cocoyl methyl taurate improves the foaming and stabilizing performance of the system, which is more than one time of the sulfate. At the same time, it is an intelligent degreasing surfactant, which can retain cholesterol and does not harm the skin barrier function. The sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer can change the micelles of the system, improve the mildness and foam performance of the system. The sugar lipid is a natural mild surfactant, which can improve the rinsing performance and cleaning ability. The present application scientifically matches the surfactant system, and the surfactants complement each other and have synergistic effect, so that the composition has excellent foam performance, mildness and use skin feel.

[0010] Preferably, the amino acid scrub cleaning composition comprises 10-40 parts of surfactant, 5-20 parts of amino acid composition, 0.5-3 parts of thickening agent, 5-20 parts of humectant, 0.1-1 part of antioxidant, 0.1-1 part of pH regulator and 30-80 parts of water.

[0011] The addition amount of the surfactant in the amino acid scrub cleaning composition of the present application can be 12 parts, 15 parts, 18 parts, 20 parts, 22 parts, 25 parts, 28 parts, 30 parts, 32 parts, 35 parts or 38 parts, etc.

[0012] The addition amount of the amino acid composition can be 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts or 19 parts, etc.

[0013] The addition amount of the thickening agent can be 0.6 parts, 0.8 parts, 1 part, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, 2.2 parts, 2.5 parts, or 2.8 parts, etc.

[0014] The addition amount of the moisturizing agent can be 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, or 19 parts, etc.

[0015] The addition amount of the antioxidant can be 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, or 0.9 parts, etc.

[0016] The addition amount of the pH adjuster can be 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, or 0.9 parts, etc.

[0017] The addition amount of the water can be 35 parts, 40 parts, 45 parts, 50 parts, 55 parts, 60 parts, 65 parts, 70 parts, 75 parts, or 80 parts, etc.

[0018] Preferably, the ratio of the addition amounts of the sodium cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfacetamide, lauryl glucoside crosspolymer, and sugar lipid is (10-20):(1-5):(1-5):(0.1-3):(0.1-2).

[0019] The "10-20" can be 11, 12, 13, 14, 15, 16, 17, 18, or 19, etc.

[0020] The first "1-5" can be 1.2, 1.5, 1.8, 2, 2.2, 2.5, 3, 3.5, 3.8, 4, 4.5, or 4.8, etc.

[0021] The second "1-5" can be 1.2, 1.5, 1.8, 2, 2.2, 2.5, 3, 3.5, 3.8, 4, 4.5, or 4.8, etc.

[0022] The "0.1-3" can be 0.3, 0.5, 0.8, 1, 1.2, 1.5, 1.8, 2, 2.2, 2.5, or 2.8, etc.

[0023] The "0.1-2" can be 0.2, 0.5, 0.7, 0.9, 1, 1.1, 1.3, 1.5, 1.7, or 1.9, etc.

[0024] Preferably, the moisturizing agent includes any one or a combination of at least two of 1,3-propanediol, 1,2-hexanediol, 1,2-pentanediol, 1,2-hexanediol, caprylyl glycol, glycerin, and ethylhexylglycerin.

[0025] Preferably, the humectant is 1,3-propanediol, 1,2-hexanediol and ethylhexylglycerin.

[0026] Preferably, the mass ratio of the 1,3-propanediol, 1,2-hexanediol and ethylhexylglycerin is (5-15):(0.5-1):(0.05-0.2).

[0027] Wherein "5-15" can be 6, 7, 8, 9, 10, 11, 12, 13 or 14, etc.

[0028] "0.5-1" can be 0.55, 0.6, 0.65, 0.7, 0.75, 0.8, 0.85, 0.9 or 0.95, etc.

[0029] "0.05-0.2" can be 0.06, 0.08, 0.1, 0.12, 0.14, 0.16 or 0.18, etc.

[0030] Preferably, the thickening agent includes any one or a combination of at least two of PEG-150 pentaerythrityl tetraisostearate, acrylates copolymer, PEG-120 methyl glucose dioleate, PEG-250 distearate.

[0031] Preferably, the antioxidant includes any one or a combination of at least two of p-hydroxyacetophenone, raspberry ketone, octanohydroxamic acid.

[0032] Preferably, the pH regulator includes any one or a combination of at least two of citric acid, sodium hydroxide, potassium hydroxide, sodium citrate.

[0033] Preferably, the amino acid composition is any one or a combination of at least two of taurine, aspartic acid, arginine, lysine, glutamic acid, alanine, glycine, histidine, threonine, serine or proline, etc.

[0034] Preferably, the amino acid composition is a combination of taurine, aspartic acid and arginine.

[0035] Preferably, the mass ratio of the taurine, aspartic acid and arginine is (5-15):(0.1-2):(0.1-4).

[0036] Wherein "5-15" can be 6, 7, 8, 9, 10, 11, 12, 13 or 14, etc.

[0037] "0.1-2" can be 0.2, 0.4, 0.6, 0.8, 1, 1.2, 1.4, 1.6 or 1.8, etc.

[0038] "0.1-4" can be 0.2, 0.5, 0.8, 1, 1.2, 1.5, 1.8, 2, 2.2, 2.5, 2.8, 3, 3.2, 3.5, or 3.8, etc.

[0039] The present application adds the combination of taurine, aspartic acid and arginine, the solubility of these amino acids in aqueous solution increases significantly with the increase of temperature, through special process, the amino acid in the material body forms uniform suspension of small needle-like crystals (see Fig. 1-2 ), so as to achieve special and technological appearance. Through the verification of the solubility and crystallization characteristics of various amino acids, the present application puts forward the best amino acid composition matching and proportion range, and through high and low temperature stability verification, these crystals can exist stably. The needle-like crystals can provide a scrubbed skin feel and improve the comfort during the cleaning process. In terms of efficacy, taurine, aspartic acid and arginine are widely used in medicine and food, but there is little research on their cosmetic skin care efficacy. At present, there is still no research on the cosmetic application and efficacy of taurine. The present application studies the efficacy performance of the amino acid scrub cleaning composition through short-term and long-term efficacy tests, and finds that the amino acid composition can provide moisturizing and anti-wrinkle effects. Few commercially available cleaning products have anti-wrinkle effect, but the amino acid scrub cleaning composition of the present application has moisturizing and anti-wrinkle efficacy, and can achieve skin care effect while cleaning.

[0040] Preferably, the amino acid scrub cleaning composition further comprises a skin conditioning agent.

[0041] Preferably, the amino acid scrub cleaning composition further comprises 0.5-5 parts of a skin conditioning agent by weight, for example, it can be 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts or 4.5 parts, etc.

[0042] Preferably, the skin conditioning agent comprises any one or a combination of at least two of phytosteryl canola sterols, PPG-13-decyltetradecin polyether-24, polyquaternium-10, hydroxypropyl guar hydroxypropyltrimonium chloride, cassia hydroxypropyltrimonium chloride, cocamidopropyl PG-dimethylcocoammonium phosphate sodium, etc.

[0043] Preferably, the skin conditioning agent is phytosteryl canola sterols, PPG-13-decyltetradecin polyether-24, cassia hydroxypropyltrimonium chloride and cocamidopropyl PG-dimethylcocoammonium phosphate sodium.

[0044] The present application adds plant-derived conditioning agents, which have good mildness, solve the problem of skin residue caused by silicone and other conditioning agents, and solve the problem of skin dryness during product use, thereby bringing a smooth and moisturizing skin feel to the system.

[0045] Preferably, the mass ratio of the phytosterols, PPG-13-decyldimonium chloride, Gellannum Hydroxypropyltrimonium Chloride and Sodium Cocamido Propyl PG-Dimethyl Chloride Phosphate is (0.1-2):(0.1-2):(0.1-0.5):(0.1-2).

[0046] The first "0.1-2" can be 0.3, 0.5, 0.8, 1, 1.2, 1.5, 1.7 or 1.9, etc.

[0047] The second "0.1-2" can be 0.3, 0.5, 0.8, 1, 1.2, 1.5, 1.7 or 1.9, etc.

[0048] The "0.1-0.5" can be 0.15, 0.2, 0.25, 0.3, 0.35, 0.4 or 0.45, etc.

[0049] The third "0.1-2" can be 0.3, 0.5, 0.8, 1, 1.2, 1.5, 1.7 or 1.9, etc.

[0050] The specific point values within the above numerical range can be selected, which will not be repeated here.

[0051] In a second aspect, the present application provides a preparation method of the amino acid scrub cleaning composition of the first aspect, which comprises:

[0052] The antioxidant, the amino acid composition, the thickening agent and the surfactant are mixed after being heated to a temperature of 80-90°C, and the pH regulator, the humectant and the optional skin conditioner are added after being cooled to a temperature of 40-50°C, and the amino acid scrub cleaning composition is obtained after standing after mixing.

[0053] The heating to a temperature of 80-90°C can be 81°C, 83°C, 85°C, 87°C or 89°C, etc.

[0054] The cooling to a temperature of 40-50°C can be 41°C, 43°C, 45°C, 47°C or 49°C, etc.

[0055] The specific point values within the above numerical range can be selected, which will not be repeated here.

[0056] In a third aspect, the present application provides the use of the amino acid scrub cleaning composition of the first aspect in the preparation of cosmetics.

[0057] Preferably, the cosmetics include shampoo, shower gel, facial cleanser or facial mask.

[0058] Preferably, the amino acid scrub cleaning composition has a mass percentage content of 0.1-20% in the cosmetic, which can be 0.3%, 0.5%, 0.8%, 1%, 3%, 5%, 7%, 9%, 10%, 12%, 15%, 17% or 19%, etc.

[0059] Preferably, the raw material composition of the cosmetic further comprises an additive, which comprises any one or a combination of at least two of a solvent, an emollient, an emulsifier, a humectant, an antioxidant, a fragrance, a chelating agent, a preservative, a solubilizer or a thickening agent.

[0060] Specific point values within the above numerical range can be selected, which will not be described here one by one.

[0061] Compared with the prior art, the present application has the following beneficial effects:

[0062] (1) The present application adopts a mild amino acid-based surfactant system. Compared with an amphoteric surfactant and glycoside-based system, the present system has rich and delicate foam, rapid foaming performance and easy rinsing, and the skin feels smooth and soft after washing. At the same time, the surfactant is limited to a combination of sodium cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfisuccinimidyl glutamate, lauryl glucoside crosslinked polymer and sugar lipid, which complement each other and synergistically improve the foam performance, mildness and use skin feel.

[0063] (2) The present application selects mild and high-foaming amino acid as the main surfactant to solve the problems of excessive degreasing and foam performance of surfactants. The combination of betaine, glycoside and biological sugar lipid can improve the fineness and stability of foam, thereby developing a mild cleaning system without sulfate, sulfonate, traditional preservative and EWG green without acne. The system achieves the effects of rich foam, intelligent cleaning, moderate degreasing and non-dry skin after washing, and is suitable for all skin. To solve the problem of single use skin feel and efficacy, the present application improves the conditioning effect by using a special surfactant system and adding a large amount of amino acid and other active substances, so that the product has a moisturizing and nourishing skin feel after washing, and has moisturizing and anti-wrinkle effects. In addition, the product of the present application also has a scientific and technological appearance and a comfortable scrubbing experience, meeting the diversified needs of consumers. BRIEF DESCRIPTION OF DRAWINGS

[0064] Fig. 1 The product appearance of the amino acid scrub cleaning composition of the present application is shown in the figure.

[0065] Fig. 2 The micrograph of the amino acid scrub cleaning composition of the present application under a microscope is shown in the figure. DETAILED DESCRIPTION

[0066] The technical solutions of the present application are further illustrated below through specific embodiments. Those skilled in the art should understand that the embodiments are only used to help understand the present application and should not be regarded as specific limitations of the present application.

[0067] The sources of some raw materials in the embodiments or comparative examples of the present application are as follows:

[0068]

[0069] The remaining raw materials can be used as long as they are purchased from regular distributors.

[0070] Example 1

[0071] The present embodiment provides an amino acid scrub cleaning composition, the composition of which is as follows:

[0072] 21 parts of surfactant, 2.5 parts of thickening agent [acrylic acid (ester) copolymer], 14.1 parts of humectant, 0.6 parts of antioxidant (raspberry ketone), 0.3 parts of pH adjuster (potassium hydroxide), 2.5 parts of skin conditioner, 14 parts of amino acid composition, and the balance is made up to 100 parts with water.

[0073] The surfactant is a mixture of cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfisuccinimidyl succinate, lauryl glucoside crosspolymer sodium, and sugar lipid at a mass ratio of 14:2:2:2:1;

[0074] The humectant is a mixture of 1,3-propanediol, 1,2-hexanediol, and ethylhexylglycerin at a mass ratio of 13:1:0.1;

[0075] The skin conditioner is a mixture of phytosteryl / peg-8 laurate, PPG-13-decyltetradecin polyether-24, cassia hydroxypropyltrimonium chloride, and cocamidopropyl PG-dimethylcetrimonium phosphate sodium at a mass ratio of 3:3:1:2;

[0076] The amino acid composition is a mixture of taurine, aspartic acid, and arginine at a mass ratio of 12:1:0.5.

[0077] The preparation method of the amino acid scrub cleaning composition is as follows:

[0078] The temperature of the emulsifying kettle is 85℃, water, the amino acid composition, and the surfactant are added, stirred and homogenized, then the thickening agent and the antioxidant are added, stirred and homogenized, the temperature is lowered to 45℃, the pH adjuster, the humectant, and the skin conditioner are added, and the mixture is stirred uniformly to obtain the amino acid scrub cleaning composition.

[0079] Example 2

[0080] The present embodiment provides an amino acid scrub cleaning composition, which is composed of the following components:

[0081] Surfactant 15 parts, thickening agent (PEG-150 Pentaerythrityl Tetraisostearate) 3 parts, humectant 18.4 parts, antioxidant (p-hydroxyacetophenone) 0.3 parts, pH regulator (potassium hydroxide) 0.3 parts, skin conditioner 5 parts, amino acid composition 6 parts, and the balance is made up to 100 parts with water.

[0082] The surfactant is a mixture of cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer, and sugar lipid in a mass ratio of 10:5:1:3:1.5;

[0083] The humectant is a mixture of 1,3-propanediol, 1,2-hexanediol, and ethylhexylglycerin in a mass ratio of 15:0.5:0.05;

[0084] The skin conditioner is a mixture of phytosteryl / peg-9 lauryl dimethicone / peg-10 dimethicone, PPG-13-decyltetradecinol ether-24, gelatin hydroxypropyltrimonium chloride, and cocamidopropyl PG-dimethylcocoammonium phosphate sodium in a mass ratio of 2:1:0.5:0.5;

[0085] The amino acid composition is a mixture of taurine, aspartic acid, and arginine in a mass ratio of 3:1:2.

[0086] The preparation method of the amino acid scrub cleaning composition is as follows:

[0087] The temperature of the emulsifying kettle is 80°C, water, the amino acid composition, and the surfactant are added, stirred and homogenized, then the thickening agent and the antioxidant are added, stirred and homogenized, the temperature is lowered to 50°C, the pH regulator, the humectant, and the skin conditioner are added, and the mixture is stirred uniformly to obtain the amino acid scrub cleaning composition.

[0088] Embodiment 3

[0089] The present embodiment provides an amino acid scrub cleaning composition, which is composed of the following components:

[0090] Surfactant 25 parts, thickening agent (PEG-250 distearate) 3 parts, humectant 8 parts, antioxidant (octanoyl hydroxamic acid) 0.7 parts, pH regulator (potassium hydroxide) 0.3 parts, skin conditioner 2 parts, amino acid composition 9 parts, and the balance is made up to 100 parts with water.

[0091] The surfactant is a mixture of cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer, and sugar lipid in a mass ratio of 20:1:5:1:2;

[0092] The humectant is 1,3-propanediol, 1,2-hexanediol and ethylhexylglycerin in a mass ratio of 5:1:0.05;

[0093] The skin conditioning agent is phytosteryl esters, PPG-13-decyldodecanol polygol ether-24, gellum gum hydroxypropyltrimonium chloride and cocamidopropyl PG-dimethylcetrimonium phosphate sodium in a mass ratio of 1:2:0.2:1;

[0094] The amino acid composition is taurine, aspartic acid and arginine in a mass ratio of 10:1:1.

[0095] The preparation method of the amino acid scrub cleaning composition is:

[0096] The emulsifying pot temperature is 80℃, water, the amino acid composition and the surfactant are added, stirring and homogenization, then the thickening agent and the antioxidant are added, stirring and homogenization, the temperature is reduced to 50℃, the pH regulator, the humectant and the skin conditioning agent are added, stirring and homogenization to obtain the amino acid scrub cleaning composition.

[0097] Example 4

[0098] The present embodiment provides an amino acid scrub cleaning composition and its application, which is different from example 1 only in that taurine is not added, and the reduced amount is made up by aspartic acid and arginine in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0099] Example 5

[0100] The present embodiment provides an amino acid scrub cleaning composition and its application, which is different from example 1 only in that aspartic acid is not added, and the reduced amount is made up by taurine and arginine in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0101] Example 6

[0102] The present embodiment provides an amino acid scrub cleaning composition and its application, which is different from example 1 only in that arginine is not added, and the reduced amount is made up by taurine and aspartic acid in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0103] Example 7

[0104] The present example provides an amino acid scrub cleaning composition and its application, which is only different from example 1 in that no skin conditioning agent is added, the reduced amount is supplemented by water, the rest of the components and the added amount are consistent with example 1, and the preparation method refers to example 1.

[0105] Example 8

[0106] The present example provides an amino acid scrub cleaning composition and its application, which is only different from example 1 in that no phytosterols are added, the reduced amount is supplemented by PPG-13-decyltetradecin polyether-24, gelatin hydroxypropyltrimethyl ammonium chloride and sodium cocamidopropyl PG-dimethyl ammonium phosphate, the rest of the components and the added amount are consistent with example 1, and the preparation method refers to example 1.

[0107] Example 9

[0108] The present example provides an amino acid scrub cleaning composition and its application, which is only different from example 1 in that no PPG-13-decyltetradecin polyether-24 is added, the reduced amount is supplemented by phytosterols, gelatin hydroxypropyltrimethyl ammonium chloride and sodium cocamidopropyl PG-dimethyl ammonium phosphate, the rest of the components and the added amount are consistent with example 1, and the preparation method refers to example 1.

[0109] Example 10

[0110] The present example provides an amino acid scrub cleaning composition and its application, which is only different from example 1 in that no gelatin hydroxypropyltrimethyl ammonium chloride is added, the reduced amount is supplemented by phytosterols, PPG-13-decyltetradecin polyether-24 and sodium cocamidopropyl PG-dimethyl ammonium phosphate, the rest of the components and the added amount are consistent with example 1, and the preparation method refers to example 1.

[0111] Example 11

[0112] The present example provides an amino acid scrub cleaning composition and its application, which is only different from example 1 in that no sodium cocamidopropyl PG-dimethyl ammonium phosphate is added, the reduced amount is supplemented by phytosterols, PPG-13-decyltetradecin polyether-24 and gelatin hydroxypropyltrimethyl ammonium chloride, the rest of the components and the added amount are consistent with example 1, and the preparation method refers to example 1.

[0113] Comparative example 1

[0114] The present embodiment provides an amino acid scrub cleaning composition and its application, which is only different from the amino acid scrub cleaning composition of example 1 in that it does not contain cocoyl glycinate, and the reduced amount is made up by cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer and sugar lipid in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0115] Comparative example 2

[0116] The present embodiment provides an amino acid scrub cleaning composition and its application, which is only different from the amino acid scrub cleaning composition of example 1 in that it does not contain cocamidopropyl hydroxysultaine, and the reduced amount is made up by cocoyl glycinate, sodium cocoyl methyl taurate, sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer and sugar lipid in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0117] Comparative example 3

[0118] The present embodiment provides an amino acid scrub cleaning composition and its application, which is only different from the amino acid scrub cleaning composition of example 1 in that it does not contain sodium cocoyl methyl taurate, and the reduced amount is made up by cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer and sugar lipid in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0119] Comparative example 4

[0120] The present embodiment provides an amino acid scrub cleaning composition and its application, which is only different from the amino acid scrub cleaning composition of example 1 in that it does not contain sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer, and the reduced amount is made up by cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate and sugar lipid in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0121] Comparative example 5

[0122] The present embodiment provides an amino acid scrub cleaning composition and its application, which is only different from the amino acid scrub cleaning composition of example 1 in that it does not contain sugar lipid, and the reduced amount is made up by cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate and sodium sulfonate hydroxypropyl lauryl glucoside cross-linked polymer in a mass ratio, and the rest of the components and the addition amount are consistent with example 1, and the preparation method refers to example 1.

[0123] Test example 1, stability evaluation

[0124] Tested samples: samples of Examples 1-11 and Comparative Examples 1-5.

[0125] Test conditions: the test samples were respectively stored at -16℃, 5℃, 25℃ and 45℃ for 3 months. The appearance of the material after being placed at each condition for 3 months was observed, and the results were recorded in Table 1 below.

[0126] Table 1

[0127]

[0128] As can be seen from Example 1, the amino acid scrubbing cleaning composition of the present application has good high and low temperature stability, and can maintain good crystal state under the condition of each temperature. As can be seen from Comparative Example 2, cocamidopropyl hydroxysultaine and PPG-13-decyltetradecinol polyether-24 have certain solubilizing ability, and have great influence on the stability and transparency of the system. As can be seen from Examples 4-6, the composition of the amino acid composition will affect the state and stability of the crystal.

[0129] Since the stability of Comparative Example 2 and Examples 4-6 and 9 does not meet the requirements, they will not be subjected to the following use feeling and efficacy tests.

[0130] Test Example 2, product safety evaluation

[0131] Human skin patch test:

[0132] Human skin patch tests were conducted on Examples 1-3, 7-8, 10-11 and Comparative Examples 1, 3-5, and then the irritation thereof was evaluated.

[0133] Test basis: Chapter 7, 2 of “Cosmetic Safety Technical Specifications” (2015 edition)

[0134] Test substance: 1% dilution of samples of Examples 1-3, 7-8, 10-11 and Comparative Examples 1, 3-5

[0135] Negative control: blank control

[0136] Subjects: a total of 30 people, male / female, aged 18-60 years old.

[0137] Suitable patch testers were selected, and the test substance was placed in the patch tester at 0.020 mL-0.025 mL in a closed patch test method. The special adhesive tape for external use was applied to the flexor of the forearm of the subject, and the test substance was removed after 24 hours. The skin reaction was observed at 30 minutes, 24 hours and 48 hours after removal, respectively. The results were recorded according to the skin reaction grading standard in “Cosmetic Safety Technical Specifications” (2015 edition) (see Table 2 below).

[0138] Table 2

[0139]

[0140] Test results: 30 subjects using the sample of Comparative Example 4 had 4 cases of first-degree reactions after the patch test was removed for 48 h. No adverse reactions were observed on the skin after the patch test was removed for 30 min, 24 h, and 48 h for the remaining samples. This indicates that the amino acid scrubbing cleansing composition of the present application has good mildness, and the sodium sulfonated hydroxypropyl lauryl glucoside crosspolymer plays a crucial role in the mildness of the system.

[0141] Test Example 3, Evaluation Test of Human Population Trial

[0142] Test objects: samples of Examples 1-3, 7-8, 10-11, and Comparative Examples 1, 3-5;

[0143] Volunteers: 77 women aged 25-40 years with sensitive skin were selected and randomly divided into 11 groups, with 7 people in each group. The volunteers in each group used the samples of Examples 1-3, 7-8, 10-11, and Comparative Examples 1, 3-5, respectively;

[0144] Test site: face;

[0145] Evaluation content: foam amount, rinsing property, comfort, after-washing moisturizing feeling.

[0146] Method of use: an appropriate amount of the test substance was taken on the hands, evenly applied to the face and massaged, and then rinsed off after cleaning. A questionnaire was used for follow-up, with a 5-point scale, 5 points being the best experience, and 1 point being the worst experience, with any value between 1 and 5 being acceptable. The average value was taken as the score, and the evaluation results are shown in Table 3 below.

[0147] Table 3

[0148]

[0149] Test results: as can be seen from Examples 1-3, the composition of the present application has excellent foam amount, rinsing property, comfort, and after-washing moisturizing feeling.

[0150] As can be seen from Examples 7-11, the addition of skin conditioning agents affects the comfort and after-washing moisturizing feeling during use, can improve the problem of dryness and roughness of the skin after washing, and the type of skin conditioning agent also has an effect on comfort and moisturizing feeling.

[0151] As can be seen from Comparative Examples 1, 3-5, cocoyl glycinate has a greater effect on rinsing property and foam amount, cocoyl methyl taurine sodium taurine sodium affects foaming, foam amount, and after-washing moisturizing feeling, sodium sulfonated hydroxypropyl lauryl glucoside crosspolymer has a greater effect on mildness and rinsing property, and thus affects comfort and moisturizing feeling, and glycolipids have a certain effect on rinsing property and moisturizing feeling. This indicates that the active system of the present application can make the product have more excellent use feeling.

[0152] Test Example 4, Moisturizing Efficacy Test

[0153] Test Substance: Samples of Examples 1-3; Control: Water.

[0154] Volunteers: 15 women, aged 25-40 years;

[0155] Test Site: Face;

[0156] Method of Use: Take an appropriate amount of the test substance on the hand, evenly apply it to the face and rub and massage, then clean and rinse.

[0157] Test Procedure: The volunteers wash the facial skin and air dry, stabilize in a constant temperature and humidity laboratory for at least 20 minutes, and test the water content of the stratum corneum of the skin on the left and right sides of the face at 0h. The left side of the face is washed with the test substance, and the right side of the face is washed with water. After 1 wash, the water content of the stratum corneum of the skin in the designated area is tested at 1h.

[0158] Test Results are shown in Table 4.

[0159] Table 4

[0160]

[0161] Conclusion: Compared with the control group, the amino acid scrubbing cleansing composition of the present application has a higher skin moisture content after 1h of use than before use, and the difference in the change from 0-1h is higher than that of the control group, indicating that the product has a certain moisturizing effect after use.

[0162] Test Example 5, Anti-wrinkle Efficacy Test

[0163] Test Substance: Sample of Example 1.

[0164] Volunteers: 5 Chinese healthy women with fine lines, wrinkles, and eye wrinkle levels of 1-5 on the face, aged 25-40 years;

[0165] Test Site: Face;

[0166] Method of Use: Take an appropriate amount of the test substance on the hand, evenly apply it to the face and rub and massage, then clean and rinse.

[0167] Test Procedure: D0: The volunteers wash the facial skin and air dry, stabilize in a constant temperature and humidity laboratory for at least 30 minutes, and test the relevant indicators (skin elasticity R2, skin tightness F4, wrinkle area ratio) of the test site of the test subjects using Cutometer dual MPA580 and VISIA CR. Guide the test subjects to use the product and note the precautions.

[0168] D14, D28: Visit the subjects, clean the face and wait. Use Cutometer dual MPA580 and VISIA CR instruments to test the relevant indicators (skin elasticity R2, skin tightness F4, wrinkle area ratio) of the test site of the subjects. The test results are shown in Table 5.

[0169] Table 5

[0170]

[0171] Test conclusion: As can be seen from Table 5, after the subjects used the product for 14 days, the skin elasticity R2 test result of the test area of the face was increased by 8.97% compared with the initial value, and after using the product for 28 days, the R2 test result was increased by 4.41% compared with the initial value. After the subjects used the product for 14 days, the skin tightness F4 test result of the test area of the face was reduced by 14.12% compared with the initial value, and after using the product for 28 days, the F4 test result was reduced by 27.10% compared with the initial value. After the subjects used the product for 14 days, the wrinkle area ratio test result of the test area of the face was reduced by 2.01% compared with the initial value, and after using the product for 28 days, the wrinkle area ratio test result was reduced by 31.09% compared with the initial value. It shows that the composition of the present application has good anti-wrinkle effect, and there are few wash-off products with anti-wrinkle effect on the market. The composition of the present application breaks through the technical bottleneck of the existing wash-off product efficacy design, and provides a formula design idea for the wash-off product of "cleaning and skin care in one".

[0172] The applicant declares that the amino acid scrubbing cleaning composition, the preparation method and the application of the present application are illustrated by the above-mentioned embodiments, but the present application is not limited to the above-mentioned embodiments, that is, it does not mean that the present application must rely on the above-mentioned embodiments to be implemented. It should be understood by those skilled in the art that any improvement of the present application, equivalent replacement of each raw material of the product of the present application, addition of auxiliary ingredients, selection of specific modes, etc. fall within the protection scope and disclosure scope of the present application.

[0173] The preferred embodiments of the present application are described in detail above, but the present application is not limited to the specific details in the above-mentioned embodiments. Within the technical concept scope of the present application, various simple modifications of the technical solutions of the present application can be made, and these simple modifications all belong to the protection scope of the present application.

[0174] In addition, it should be noted that each specific technical feature described in the above-mentioned specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present application will not further describe various possible combination manners.

Claims

1. An amino acid scrub cleaning composition characterized in that, The amino acid scrub cleaning composition comprises a surfactant, an amino acid composition, a thickening agent, a moisturizing agent, an antioxidant, a pH regulator and water. The surfactant is a combination of cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfite, lauryl glucoside crosspolymer and sugar lipid.

2. The amino acid scrub cleaning composition of claim 1, wherein, The amino acid scrub cleaning composition comprises, by weight fraction, 10-40 parts of a surfactant, 5-20 parts of an amino acid composition, 0.5-3 parts of a thickening agent, 5-20 parts of a moisturizing agent, 0.1-1 part of an antioxidant, 0.1-1 part of a pH regulator and 30-80 parts of water.

3. The amino acid scrub cleanser composition of claim 1, wherein, The surfactant is a combination of cocoyl glycinate, cocamidopropyl hydroxysultaine, sodium cocoyl methyl taurate, sodium sulfite, lauryl glucoside crosspolymer and sugar lipid. The moisturizing agent is 1,3-propanediol, 1,2-hexanediol and ethylhexylglycerin.

4. The amino acid scrub cleanser composition of claim 1, wherein, The thickening agent comprises any one or a combination of at least two of PEG-150 pentaerythrityl tetraisostearate, acrylates copolymer, PEG-120 methyl glucose dioleate and PEG-250 distearate. The antioxidant comprises any one or a combination of at least two of p-hydroxyacetophenone, raspberry ketone and octanohydroxamic acid. The pH regulator comprises any one or a combination of at least two of citric acid, sodium hydroxide, potassium hydroxide and sodium citrate.

5. The amino acid scrub cleanser composition of claim 1, wherein, The amino acid composition is a combination of taurine, aspartic acid and arginine.

6. The amino acid scrub cleanser composition of claim 1, wherein, The amino acid scrub cleaning composition further comprises, by weight fraction, 0.5-5 parts of a skin conditioning agent. The skin conditioning agent comprises any one or a combination of at least two of phytosteryl esters, PPG-13-decyltetradecineth-24, polyquaternium-10, hydroxypropyl guar hydroxypropyltrimonium chloride, cassia hydroxypropyltrimonium chloride, cocamidopropyl PG-dimethylcocoammonium phosphate sodium and the like.

7. The amino acid scrub cleanser composition of claim 6, wherein The skin conditioning agent is phytosteryl esters, PPG-13-decyltetradecineth-24, cassia hydroxypropyltrimonium chloride and cocamidopropyl PG-dimethylcocoammonium phosphate sodium. The mass ratio of phytosteryl esters, PPG-13-decyltetradecineth-24, cassia hydroxypropyltrimonium chloride and cocamidopropyl PG-dimethylcocoammonium phosphate sodium is (0.1-2):(0.1-2):(0.1-0.5):(0.1-2).

8. A process for the preparation of an amino acid scrub cleaning composition according to any one of claims 1 to 7, characterized in that, The preparation method comprises: The antioxidant, the amino acid composition, the thickening agent and the surfactant are heated to a temperature of 80-90℃ and then mixed with water, and the pH regulator, the moisturizing agent and optionally the skin conditioning agent are added after the temperature is lowered to 40-50℃, and the mixture is left to stand to obtain the amino acid scrub cleaning composition.

9. Use of the amino acid scrub cleaning composition according to any one of claims 1-7 in the preparation of a cosmetic product.

10. The use according to claim 9, wherein the compound is ###00003### or a pharmaceutically acceptable salt thereof. The cosmetic product comprises shampoo, shower gel, facial cleanser or facial mask. The raw material composition of the cosmetic further includes an additive, which includes any one or a combination of at least two of a solvent, an emollient, an emulsifier, a humectant, an antioxidant, a fragrance, a chelating agent, a preservative, a solubilizer, or a thickening agent. The raw material composition of the cosmetic further includes an additive, which includes any one or a combination of at least two of a solvent, an emollient, an emulsifier, a humectant, an antioxidant, a fragrance, a chelating agent, a preservative, a solubilizer, or a thickening agent.

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