Foot-worn physiological sensor and system including same

Abstract

A system for measuring at least one physiological parameter of a subject includes a wearable device configured to be secured to a foot of the subject and a sensor component removably securable to the wearable device. The sensor component is removably securable to the wearable device and includes one or more sensors for measuring the at least one physiological parameter of the subject. In some implementations, the sensor component includes a sensor strap configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device, thereby securing the wearable device and the sensor component to the subject's foot.

Description

[Technical field]

[0001] INCORPORATION BY REFERENCE TO PRIORITY APPLICATIONS This application claims the benefit of priority under 35 U.S.C. § 119(e) to U.S. Provisional Patent Application No. 63 / 387,045, filed December 12, 2022, and U.S. Provisional Patent Application No. 63 / 318,568, filed March 10, 2022. All of the above-mentioned applications are incorporated herein by reference in their entireties. Any and all applications in which a foreign or domestic priority claim is identified in an Application Data Sheet filed with this application are incorporated herein by reference under 37 CFR 1.57.

[0002] The present disclosure relates to wearable systems, devices, and methods for measuring and / or monitoring physiological information of a subject. [Background technology]

[0003] Pulse oximetry is a widely accepted non-invasive procedure for measuring arterial blood oxygen saturation levels, an indicator of a person's oxygen supply. A pulse oximetry sensor generally includes one or more light sources that transmit optical radiation into or reflect through a body part. After attenuation by tissue and fluids in the body part, one or more light detecting devices detect the attenuated light and output one or more detector signals in response to the detected attenuated light. Pulse oximetry sensors can be used to determine a variety of physiological parameters and / or traits, including, but not limited to, oxygen saturation (SpO2), pulse rate, plethysmographic waveform, perfusion index (PI), pleth variability index (PVI), methemoglobin (MetHb), carboxyhemoglobin (CoHb), total hemoglobin (tHb), glucose, and / or others, and can be used to display the foregoing parameters on one or more monitors, individually, in groups, trends, in combinations, or as an overall wellness or other index. Devices incorporating pulse oximetry can be used in medical settings (e.g., hospitals and nursing homes) and non-hospital settings (e.g., homes). [Prior art documents] [Patent documents]

[0004] [Patent Document 1] US Patent Application Publication No. 2021 / 0290072 [Patent Document 2] U.S. Patent Application Serial No. 17 / 206,907 [Patent Document 3] US Patent Application Publication No. 2023 / 0045000 Summary of the Invention [Problem to be solved by the invention]

[0005] In some circumstances, especially for infants with small hands and fingers, it may be advantageous to select the foot as a site for pulse oximetry. The present disclosure describes various implementations of the system that are secured to the subject (e.g., the subject's foot, ankle, and / or lower leg). Some implementations include one or more sensors for determining physiological and / or motion data. Some implementations of the system disclosed herein use pulse oximetry at the subject's foot. Various implementations disclosed herein provide improved user comfort, improved ergonomics, improved convenience, promote better sensor-skin contact and engagement to provide more accurate physiological parameter determination, and provide better stability with respect to securing. Various implementations of the system disclosed herein can be utilized in medical environments (e.g., hospitals or other care facilities, etc.) and non-hospital environments (e.g., homes, etc.). [Means for solving the problem]

[0006] Some implementations of the systems disclosed herein include a wearable device configured to be secured to a subject's foot and a sensor component. In some implementations, the sensor component is removably securable to the wearable device. The sensor component can include one or more sensors for determining physiological and / or motion data. In some implementations, the sensor component includes at least one emitter and at least one detector that provide pulse oximetry functionality. In some implementations, the sensor component includes a sensor hub removably securable to a portion of the wearable device; and a sensor strap configured to wrap around a portion of the subject's foot and secure to a portion of the wearable device, thereby securing the sensor hub and the wearable device to the subject's foot. The sensor hub and the sensor strap can include various electronic components and, in some implementations, can form a unitary structure with each other. In some implementations, the sensor hub includes a power source and one or more processors. In some implementations, the wearable device does not include a power source. In some variations, the wearable device and the sensor component are integral with each other (e.g., not separable from each other).

[0007] Advantageously, some implementations of the systems disclosed herein can be easily adapted and / or customized to fit subjects having body parts (e.g., feet, ankles, and / or lower legs) of various sizes and / or shapes. For example, some implementations of the systems disclosed herein include a wearable device that is removable from the electronic components of the system (e.g., the sensor components discussed above), which allows different sizes of wearable devices to be selected and utilized with the same electronic components of the system. As another example, the systems disclosed herein can have one or more adjustable straps that can allow for customized fitting of the system to the subject's feet. Additionally, the systems described herein (or portions thereof, such as the wearable devices) can be made from elastic materials that can accommodate and / or conform to various sizes and / or shapes of feet, ankles, and / or lower legs. Additionally, the systems disclosed herein (or portions thereof, such as wearable devices) can be provided in a variety of sizes and / or shapes (e.g., small, medium, large) to further allow for a customized fit for the subject.

[0008] Some implementations of the systems disclosed herein can advantageously provide a reusable and / or durable (e.g., lasting for weeks and / or months). Some implementations of the systems disclosed herein incorporate at least one detector into a strap that, when wrapped around a portion of the subject's foot, operably positions the at least one detector adjacent to an upper portion of the subject's foot. Some of such implementations include at least one emitter in a portion of the system that is operably positioned adjacent to a bottom portion of the subject's foot and / or is substantially aligned with the at least one detector. Some variations include alternative positioning of such at least one emitter and such at least one detector.

[0009] Disclosed herein is a system for measuring at least one physiological parameter of a subject, the system including: a wearable device configured to be secured to a foot of the subject; and a sensor component removably secureable to the wearable device and including one or more sensors for measuring the at least one physiological parameter of the subject, the sensor component further including a sensor strap configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device, thereby securing the wearable device and the sensor component to the subject's foot.

[0010] In some implementations, the sensor strap includes a first portion of a sensor component configured to be wrapped around the portion of the subject's foot and secured to a first portion of a wearable device; and a second portion of the sensor component configured to be removably secured to a second portion of the wearable device. In some implementations, the wearable device defines a first volume configured to receive the subject's foot and a second volume configured to removably receive the second portion of the sensor component. The second portion of the sensor component can be any of the sensor hubs described and / or illustrated herein. In some implementations, the wearable device includes a base configured to contact at least a portion of a bottom of the subject's foot, the second volume of the wearable device being formed by a cavity in the base; and a wall extending outwardly from the base and configured to surround at least a portion of a heel and one or more sides of the subject's foot. In some implementations, the wearable device further includes a frame disposed within the cavity, the frame configured to removably secure the second portion of the sensor component; the base and the wall form a unitary structure made from a first material; and the frame is made from a second material that is more rigid than the first material. The wearable device can be formed, for example, by overmolding the base and / or the wall onto the frame (e.g., via injection molding). In some implementations, the first portion of the wearable device is disposed on a portion of the wall. In some implementations, the first portion of the wearable device includes an opening in the portion of the wall, and the sensor strap is configured to be inserted through the opening.In some implementations, the first volume is defined by the base and the wall at a location above the cavity of the base. In some implementations, the wall extends around a portion of a peripheral edge of the base. In some implementations, the wall extends around less than the entire peripheral edge of the base. In some implementations, the wall does not extend around the entire cavity.

[0011] In some implementations, the sensor component includes a sensor hub including one or more processors, the sensor hub configured to be removably secured to the second portion of the wearable device, the sensor strap connected to the sensor hub and extending outwardly from the sensor hub; one or more emitters configured to emit optical radiation into tissue of the subject's foot, the one or more emitters positioned in the sensor hub; and one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through tissue and output at least one signal in response to the detected optical radiation, the one or more detectors positioned in the sensor strap, the one or more processors of the sensor hub configured to receive the at least one signal output by the one or more detectors and determine the at least one physiological parameter of the subject.

[0012] In some implementations, the system is configured such that when the sensor hub is secured to the second portion of the wearable device and the sensor strap is secured to the first portion of the wearable device, the one or more detectors are positioned adjacent to a top or side portion of the subject's foot and the one or more emitters are positioned adjacent to a bottom portion of the subject's foot.

[0013] In some implementations, the sensor hub and the sensor strap form a unitary structure. In some implementations, the sensor strap includes a first section connected to the sensor hub and extending outwardly from the sensor hub, where the one or more detectors are positioned within the first section; and a second section releasably connectable to the first section, where the second section is configured to be secured to the first portion of the wearable device. In some implementations, the first section and the second section have different lengths and / or comprise different materials. In some implementations, the first section is more stretchable than the second section. In some implementations, the sensor strap is configured to be stretched to allow adjustment of the position of the one or more detectors relative to the subject's foot. In some implementations, the sensor hub includes a housing including an opening configured to be positioned adjacent to the skin of the subject's foot when the sensor hub is secured to the second portion of the wearable device; a thermally conductive probe positioned at least partially within the opening; and a temperature sensor positioned within the housing. In some implementations, the thermally conductive probe is configured to transmit thermal energy from the skin at least partially toward the temperature sensor. In some implementations, the thermally conductive probe extends through the opening and is configured to contact the skin of the subject's foot.

[0014] In some implementations, the sensor strap is configured to be wrapped around a portion of the subject's foot and secured to a first portion of the wearable device; the system further includes an additional strap, the additional strap being removably securable to a second portion of the wearable device and configured to (i) be wrapped around another portion of the subject's foot or a portion of the subject's ankle or leg, and (ii) be secured to a third portion of the wearable device. The sensor strap can be secured to the first portion of the wearable device in various ways (e.g., by inserting a portion of the sensor strap through an opening in the first portion of the wearable device and then securing the portion of the sensor strap to itself). Similarly, the additional strap can be secured to the third portion of the wearable device by inserting a portion of the additional strap through an opening in the third portion of the wearable device and then securing the portion of the additional strap to itself. In some implementations, the sensor strap is configured to be wrapped around a portion of the subject's foot and secured to a first portion of the wearable device; the system further includes an additional strap, the additional strap having a first end and a second end, the first end being connected to the second portion of the wearable device, and the second end being configured to (i) be wrapped around another portion of the subject's foot or a portion of the subject's ankle or leg, and (ii) be secured to a third portion of the wearable device. The sensor strap can be secured to the first portion of the wearable device in various ways, for example, by inserting a portion of the sensor strap through an opening in the first portion of the wearable device and then securing the portion of the sensor strap to itself. Similarly, the additional strap can be secured to the third portion of the wearable device by inserting a portion of the additional strap through an opening in the third portion of the wearable device and then securing the portion of the additional strap to itself.

[0015] Disclosed herein is a system for measuring at least one physiological parameter of a subject, the system including: a wearable device configured to be secured to a foot of the subject, the wearable device including a cavity; a sensor hub configured to be removably secured within the cavity of the wearable device, the sensor hub including one or more processors; a sensor strap connected to and extending outwardly from the sensor hub and configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device; one or more emitters configured to emit optical radiation into tissue of the subject's foot, the one or more emitters disposed in one of the sensor hub and the sensor strap; and one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through the tissue and to output at least one signal in response to the detected optical radiation, the one or more detectors disposed in the other of the sensor hub and the sensor strap. In some implementations, the one or more processors of the sensor hub are configured to receive at least one signal output by the one or more detectors and determine at least one physiological parameter of the subject.

[0016] In some implementations, the wearable device is configured such that the cavity is positioned adjacent to a bottom portion of the subject's foot when the wearable device is secured to the subject's foot. In some implementations, the system is configured such that the one or more detectors are configured to be positioned adjacent to an upper portion of the subject's foot when the system is in use; and the one or more emitters are configured to be positioned adjacent to a bottom portion of the subject's foot when the system is in use. In some implementations, the sensor hub is secured in the cavity, and the one or more detectors are disposed in the sensor strap to face toward the sensor hub; and the one or more emitters are disposed in the sensor hub to face toward the sensor strap when the sensor hub is secured to a portion of the wearable device. In some implementations, the sensor hub and the sensor strap form a unitary structure. In some implementations, the sensor strap includes a first section connected to the sensor hub and extending outwardly from the sensor hub, where the one or more detectors are positioned within the first section; and a second section releasably connectable to the first section, where the second section is configured to be secured to a portion of the wearable device. In some implementations, the first section and the second section have different lengths. In some implementations, the first section is more stretchable than the second section.

[0017] In some implementations, the wearable device includes a main body and a frame. The main body can include a base configured to contact at least a portion of the bottom of a subject's foot, the base including the cavity; and a wall extending outwardly from the base and configured to encircle at least a portion of the heel and one or more sides of the subject's foot. A frame can be positioned within the cavity, the frame configured to removably secure to the sensor hub. In some implementations, the main body is made of a first material and the frame is made of a second material that is stiffer than the first material. The wearable device can be formed, for example, by overmolding the base and / or the wall onto the frame (e.g., via injection molding). In some implementations, the base includes a base surface configured to contact at least a portion of a bottom of a subject's foot; the cavity has a first depth below the base surface; and the wearable device further includes a recess positioned along an outer edge of the base adjacent to the cavity, the recess having a second depth below the base surface, the second depth being less than the first depth and substantially equal to a thickness of a sensor strap, the recess configured to receive a portion of the sensor strap when the sensor hub is secured within the cavity, such that the sensor hub and the portion of the sensor strap form a substantially flush surface with the base surface.

[0018] In some implementations, the sensor strap is configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device, the portion of the wearable device being a first portion of the wearable device; the system further includes an additional strap, separate from the sensor strap, configured to (i) be wrapped around another portion of the subject's foot or a portion of the subject's ankle or leg, and (ii) be secured to a second portion of the wearable device. The sensor strap can be secured to the first portion of the wearable device in various ways (e.g., by inserting a portion of the sensor strap through an opening in the first portion of the wearable device and then securing the portion of the sensor strap to itself). Similarly, the additional strap can be secured to the second portion of the wearable device by inserting a portion of the additional strap through an opening in the second portion of the wearable device and then securing the portion of the additional strap to itself. In some implementations, the sensor hub includes a housing including an opening configured to be positioned adjacent to the skin of a subject's foot when the sensor hub is secured in a cavity of a wearable device; a thermal conductivity probe positioned at least partially in the opening; and a temperature sensor positioned in the housing. In some implementations, the thermal conductivity probe is configured to transmit thermal energy from the skin at least partially toward the temperature sensor. In some implementations, the thermal conductivity probe extends through the opening and is configured to contact the skin when the system is in use.

[0019] In some implementations, the one or more detectors are disposed in a sensor strap and the one or more emitters are disposed in a sensor hub; the wearable device further includes a flexible circuit, the flexible circuit extending into a portion of the sensor hub and a portion of the sensor strap and electrically connecting the one or more detectors to one or more processors or to another circuit to which the one or more processors are connected; the portion of the sensor strap is configured to be stretched from a first state to a second state, the portion of the sensor strap having a greater length when in the second state than when in the first state; the one or more detectors are disposed at a first location within the portion of the sensor strap that is spaced a first distance from the sensor hub; a length of a portion of the flexible circuit positioned within the portion of the sensor strap is greater than the first distance, allowing the flexible circuit to accommodate the stretching of the portion of the sensor strap from the first state to the second state while maintaining a connection between the one or more detectors and the one or more processors or the another circuit to which the one or more processors are connected. In some implementations, the one or more detectors are disposed in a sensor strap and the one or more emitters are disposed in a sensor hub; the sensor strap is configured to be stretched to allow adjustment of a position of the one or more detectors relative to the subject's foot.

[0020] For purposes of summarizing the present disclosure, certain aspects, advantages, and novel features of some implementations have been described herein. It should be understood that not all such advantages are necessarily realized in accordance with any particular implementation of the technology disclosed herein. Thus, the implementations disclosed herein can be implemented or performed in a manner that realizes or optimizes one advantage or group of advantages as taught herein, without necessarily realizing other advantages that may be taught or suggested herein.

[0021] Certain features of the present disclosure are described below with reference to the drawings. The illustrated implementations are intended to illustrate, but not limit, the implementations. Various features of different disclosed implementations can be combined to form further implementations that are part of the present disclosure. [Brief description of the drawings]

[0022] [Figure 1A] FIG. 1 is a perspective view of a system secured to a subject's foot, according to an aspect of the present disclosure. [Figure 1B] FIG. 1 is a perspective view of a system secured to a subject's foot, according to an aspect of the present disclosure. [Figure 1C] FIG. 1C illustrates the system of FIGS. 1A-1B in wireless communication with an exemplary computing device, according to an aspect of the present disclosure. [Figure 1D] FIG. 1C is a cross-sectional view of the system of FIGS. 1A-1B secured to a subject's foot, according to an embodiment of the present disclosure. [Figure 2A] FIG. 2 is a perspective view of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 2B] FIG. 2 is a perspective view of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 2C] FIG. 2 is a perspective view of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 2D]FIG. 1C is a perspective view of the system of FIGS. 1A-1B with the sensor hub detached from the sensor dock and the wearable device, according to an embodiment of the present disclosure. [Figure 2E] FIG. 1C is a perspective view of the system of FIGS. 1A-1B with the sensor hub detached from the sensor dock and the sensor dock detached from the wearable device, according to an embodiment of the present disclosure. [Diagram 3] 1C is a schematic diagram of certain optional features of the system of FIGS. 1A-1B, according to an embodiment of the present disclosure. [Figure 4A] 1A-1B are various perspective views of a sensor dock of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 4B] 1A-1B are various perspective views of a sensor dock of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 4C] 1A-1B are various perspective views of a sensor dock of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 4D] 1A-1B are various perspective views of a sensor dock of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 4E] 1A-1B are various perspective views of a sensor dock of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 4F] 1A-1B are various perspective views of a sensor dock of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 4G] 1A-1B are various perspective views of a sensor dock of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 5A] FIG. 2 is a perspective view of a sensor hub of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 5B] FIG. 2 is a perspective view of a sensor hub of the system of FIGS. 1A-1B according to an embodiment of the present disclosure. [Figure 5C] FIG. 5C is a bottom view of the sensor hub of FIGS. 5A-B according to an embodiment of the present disclosure. [Figure 5D] FIG. 5C is a top view of the sensor hub of FIGS. 5A-B according to an embodiment of the present disclosure. [Figure 5E]FIG. 5C is a side view of the sensor hub of FIGS. 5A-B according to an embodiment of the present disclosure. [Figure 5F] FIG. 5C is a side view of the sensor hub of FIGS. 5A-B according to an embodiment of the present disclosure. [Figure 5G] FIG. 5C is a front view of the sensor hub of FIGS. 5A-5B according to an embodiment of the present disclosure. [Figure 5H] FIG. 5C is a rear view of the sensor hub of FIGS. 5A-B according to an embodiment of the present disclosure. [Figure 5I] FIG. 5C is an exploded perspective view of the sensor hub of FIGS. 5A-5B according to an embodiment of the present disclosure. [Figure 5J] FIG. 5C is an exploded perspective view of the sensor hub of FIGS. 5A-5B according to an embodiment of the present disclosure. [Figure 6A] 1A-1B depict various perspective views of a wearable device of the system of FIG. 1A according to an embodiment of the present disclosure. [Figure 6B] 1A-1B depict various perspective views of a wearable device of the system of FIG. 1A according to an embodiment of the present disclosure. [Figure 6C] 1A-1B depict various perspective views of a wearable device of the system of FIG. 1A according to an embodiment of the present disclosure. [Figure 6D] 1A-1B depict various perspective views of a wearable device of the system of FIG. 1A according to an embodiment of the present disclosure. [Figure 7A] FIG. 1 is a perspective view of a charging station according to an aspect of the present disclosure. [Figure 7B] FIG. 1 is a perspective view of a charging station according to an aspect of the present disclosure. [Figure 7C] FIG. 7C is a top view of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7D] FIG. 7C is a bottom view of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7E] FIG. 7C is a front view of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7F] FIG. 7C is a rear view of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7G]FIG. 7C is a side view of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7H] FIG. 7C is a side view of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7I] FIG. 7C is an enlarged top perspective view of a portion of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7J] FIG. 7C is an enlarged top perspective view of a portion of the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 7K] FIG. 8 is a perspective cross-sectional view taken through the charging station of FIGS. 7A-7B according to an embodiment of the present disclosure. [Figure 8A] FIG. 13 is a perspective view of another implementation of a system secured to a subject's foot in accordance with aspects of the present disclosure. [Figure 8B] FIG. 13 is a perspective view of another implementation of a system secured to a subject's foot in accordance with aspects of the present disclosure. [Figure 8C] FIG. 8C is a cross-sectional view of the system of FIGS. 8A-8B secured to a subject's foot, according to an embodiment of the present disclosure. [Figure 9A] FIG. 8C is a perspective view of the system of FIGS. 8A-8B according to an embodiment of the present disclosure. [Figure 9B] FIG. 8C is a perspective view of the system of FIGS. 8A-8B according to an embodiment of the present disclosure. [Figure 9C] FIG. 8C is a perspective view of the system of FIGS. 8A-8B according to an embodiment of the present disclosure. [Figure 9D] FIG. 8C is a perspective view of the system of FIGS. 8A-8B with the sensor hub detached from the sensor dock and the wearable device, according to an embodiment of the present disclosure. [Figure 9E] FIG. 8C is a perspective view of the system of FIGS. 8A-8B with the sensor hub detached from the sensor dock and the sensor dock detached from the wearable device, according to an embodiment of the present disclosure. [Figure 10A] 8A-8B , according to an embodiment of the present disclosure. [Figure 10B]8A-8B , according to an embodiment of the present disclosure. [Figure 10C] 8A-8B , according to an embodiment of the present disclosure. [Figure 10D] 8A-8B , according to an embodiment of the present disclosure. [Figure 10E] 8A-8B, according to an embodiment of the present disclosure. [Figure 10F] 8A-8B, according to an embodiment of the present disclosure. [Figure 11A] 8A-8B, according to an embodiment of the present disclosure. [Figure 11B] 8A-8B, according to an embodiment of the present disclosure. [Figure 11C] 8A-8B, according to an embodiment of the present disclosure. [Figure 11D] 8A-8B, according to an embodiment of the present disclosure. [Figure 11E] 8A-8B, according to an embodiment of the present disclosure. [Figure 11F] FIG. 8C is a perspective view of a wearable device strap and a connector portion of the wearable device of the system of FIGS. 8A-8B according to an embodiment of the present disclosure. [Figure 11G] FIG. 8C is a perspective view of a wearable device strap and a connector portion of the wearable device of the system of FIGS. 8A-8B according to an embodiment of the present disclosure. [Figure 11H] FIG. 8C is a perspective view of a connector portion of a sensor strap of the system of FIGS. 8A-8B according to an embodiment of the present disclosure. [Figure 11I]FIG. 8C is a perspective view of a connector portion of a sensor strap of the system of FIGS. 8A-8B according to an embodiment of the present disclosure. [Figure 12A] FIG. 13 is a perspective view of another implementation of a system secured to a subject's foot in accordance with aspects of the present disclosure. [Figure 12B] FIG. 13 is a perspective view of another implementation of a system secured to a subject's foot in accordance with aspects of the present disclosure. [Figure 12C] FIG. 12C is a cross-sectional view of the system of FIGS. 12A-12B secured to a subject's foot, according to an embodiment of the present disclosure. [Figure 13A] FIG. 12C is a perspective view of the system of FIGS. 12A-12B according to an embodiment of the present disclosure. [Figure 13B] FIG. 12C is a perspective view of the system of FIGS. 12A-12B according to an embodiment of the present disclosure. [Figure 13C] FIG. 12C is a perspective view of the system of FIGS. 12A-12B according to an embodiment of the present disclosure. [Figure 13D] FIG. 12C is a perspective view of the system of FIGS. 12A-B with the sensor component detached from the wearable device, according to an embodiment of the present disclosure. [Figure 13E] FIG. 12C is a perspective view of the system of FIGS. 12A-B with the sensor component detached from the wearable device, according to an embodiment of the present disclosure. [Figure 14A] 12A-12B according to an embodiment of the present disclosure. [Figure 14B] 12A-12B according to an embodiment of the present disclosure. [Figure 14C] 12A-12B according to an embodiment of the present disclosure. [Figure 14D] 12A-12B according to an embodiment of the present disclosure. [Figure 14E] 12A-12B according to an embodiment of the present disclosure. [Figure 14F] 12A-12B according to an embodiment of the present disclosure. [Figure 14G] 12A-12B according to an embodiment of the present disclosure. [Figure 15A] 12A-12B, according to an embodiment of the present disclosure. [Figure 15B] 12A-12B, according to an embodiment of the present disclosure. [Figure 15C] 12A-12B, according to an embodiment of the present disclosure. [Figure 15D] 12A-12B, according to an embodiment of the present disclosure. [Figure 15E] 12A-12B, according to an embodiment of the present disclosure. [Figure 16A] FIG. 13 is a perspective view of another implementation of a system configured to be secured to a subject's foot, according to aspects of the present disclosure. [Figure 16B] FIG. 13 is a perspective view of another implementation of a system configured to be secured to a subject's foot, according to aspects of the present disclosure. [Figure 16C] FIG. 16C is a perspective view of the system of FIGS. 16A-B with the sensor component detached from the wearable device, according to an embodiment of the present disclosure. [Figure 16D] FIG. 16C is a perspective view of the system of FIGS. 16A-B with the sensor component detached from the wearable device, according to an embodiment of the present disclosure. [Figure 17A] 16A-16B , according to an embodiment of the present disclosure. [Figure 17B]16A-16B , according to an embodiment of the present disclosure. [Figure 17C] 16A-16B , according to an embodiment of the present disclosure. [Figure 17D] 16A-16B , according to an embodiment of the present disclosure. [Figure 18A] 16A-16B , according to an embodiment of the present disclosure. [Figure 18B] 16A-16B , according to an embodiment of the present disclosure. [Figure 18C] 16A-16B , according to an embodiment of the present disclosure. [Figure 18D] 16A-16B , according to an embodiment of the present disclosure. [Figure 19A] FIG. 1 illustrates an exemplary monitoring system according to aspects of the present disclosure. [Figure 19B] 19B is a schematic representation of the monitoring system of FIG. 19A according to an embodiment of the present disclosure. [Figure 20] 19A-19B, according to an embodiment of the present disclosure; FIG. 19B is a schematic diagram of certain optional features of the embodiment of the monitoring system of FIG. [Figure 21A] 19B is a perspective view of a camera of the monitoring system of FIG. 19A according to an embodiment of the present disclosure. [Figure 21B] 19B is a perspective view of a camera of the monitoring system of FIG. 19A according to an embodiment of the present disclosure. [Figure 21C] 21A-21B are schematic diagrams of certain optional features of the camera of FIG. 21A-B, according to an embodiment of the present disclosure. [Figure 22A] 19B-19C are various perspective views of a hub of the monitoring system of FIG. 19A according to an embodiment of the present disclosure. [Figure 22B] 19B-19C are various perspective views of a hub of the monitoring system of FIG. 19A according to an embodiment of the present disclosure. [Figure 22C] 19B-19C are various perspective views of a hub of the monitoring system of FIG. 19A according to an embodiment of the present disclosure. [Figure 22D] 22A-22C are schematic diagrams of certain optional features of the hub of FIG. 22A-C, according to an embodiment of the present disclosure. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0023] Various features and advantages of the present disclosure will now be described with reference to the accompanying figures. The following description is merely exemplary in nature and is in no way intended to limit the present disclosure, its application, or uses. The present disclosure extends beyond the specifically disclosed implementations and / or uses, as well as obvious modifications and equivalents thereof. Thus, it is intended that the scope of the present disclosure should not be limited by any particular implementation described below. Features of the illustrated implementations can be modified, combined, removed, and / or substituted as would be apparent to one skilled in the art in light of the principles disclosed herein. Moreover, the implementations disclosed herein may include several novel features, no single one of which is solely responsible for any desirable attributes or is necessary to practice the systems, devices, and / or methods disclosed herein.

[0024] Disclosed herein is a system that may be used to measure, monitor, transmit (e.g., wirelessly or via a wired connection), process, and / or determine one or more physiological parameters (which may also be referred to herein as “physiological data”), movement data, and / or location data of a subject (which may also be referred to herein as a “user,” “patient,” or “wearer”). The disclosed system is capable of generating one or more signals associated with and / or indicative of one or more physiological parameters, movement data, and / or location data of the subject, processing such one or more signals, and determining such physiological parameters, movement data, and / or location data. Some implementations of the disclosed system generate and transmit (wirelessly or via a wired connection) one or more signals associated with and / or indicative of one or more physiological parameters, movement data, and / or location data of the subject to a separate monitoring and / or computing device (e.g., a patient monitor), which may process and / or determine such physiological parameters, movement data, and / or location data based on the transmitted signals. The systems disclosed herein can continuously or intermittently measure, monitor, transmit, process, and / or determine such physiological parameters, motion data, and / or location data. Any of the disclosed systems and / or devices in communication with the disclosed systems can include hardware and / or software capable of determining and / or monitoring various physiological parameters (including, but not limited to, blood oxygenation levels in veins and / or arteries, heart rate, blood flow, respiratory rate, body temperature, and / or other physiological parameters or attributes such as those discussed herein).Any of the systems described herein may include pulse oximetry and / or use pulse oximetry (e.g., via an optical sensor) to measure a physiological parameter of a subject and / or generate, transmit, and / or process one or more signals associated with and / or indicative of such physiological parameter and / or determine such physiological parameter. As discussed below, such optical sensors may include one or more emitters configured to emit optical radiation (e.g., light) of one or more wavelengths (e.g., wavelengths in the visible spectrum, near-infrared wavelengths, infrared wavelengths, far-infrared wavelengths, etc.) and one or more detectors configured to detect at least a portion of the emitted optical radiation after attenuation and / or after passing through tissue of the subject.

[0025] 1A-1B illustrate perspective views of a system 100 (which may also be referred to herein as a "wearable system," "wearable sensor system," or "wearable physiological sensor system") secured to a foot 2 of a subject 1. As shown, when secured to the subject's foot 2, the system 100 may also be secured to the ankle 3, heel 4, and / or lower leg 5 of the subject 1. As further shown, when secured to the subject's foot 2, the system 100 may support the subject's foot 2, ankle 3, heel 4, and / or lower leg 5. The system 100 may include a wearable device, a sensor dock, and a sensor hub, all of which are discussed further below.

[0026] 1A-1B show the system 100 secured to the foot 2 of the subject 1 in a particular manner that can provide certain advantages as described herein, but such illustrated manner and / or location of securing is not intended to be limiting. The system 100 can be secured to various portions of the subject's foot 2, ankle 3, heel 4, and / or lower leg 5 in various manners and / or using various methods. Thus, while the system 100 is described herein primarily with reference to the foot 2, ankle 3, heel 4, and / or lower leg 5 of the subject 1, such description is not intended to be limiting. Additionally, while the system 100 is shown secured to the left foot of the subject 1, the system 100 can be secured to either the left or right foot of the subject 1. FIG. 1C illustrates the system 100 of FIGS. 1A-1B, which is secured to the subject 1 and communicates wirelessly with one or more separate computing devices (which may be, for example, a patient monitor 10a as shown (which may also be referred to herein as an “external patient monitor”) and / or a mobile phone 10b) via any of a variety of wireless communication protocols (such as, for example, any of those discussed herein). The system 100 may wirelessly transmit physiological, movement, and / or location data of the subject to the separate computing devices 10 (e.g., 10a, 10b, or others), as further described herein.

[0027] 1D illustrates a cross-section of the system of FIGS. 1A-1B secured to a subject's foot 2. As shown, when secured to the subject's foot 2, the system 100 is capable of operably positioning one or more emitters 104a and one or more detectors 104b on either side of the subject's foot 2. Also, as shown, when secured to the subject's foot 2, the system 100 is capable of operably positioning one or more temperature sensors 104c adjacent the bottom of the subject's foot 2.

[0028] 2A-2E illustrate various perspective views of the system 100 of FIG. 1A. The system 100 may include a wearable device 102. The wearable device 102 may be configured to receive and / or secure an electronic device including one or more sensors for monitoring information regarding physiological parameters, movement, and / or location of the subject 1. For example, the wearable device may be configured to receive and / or secure a sensor component 103 (which may also be referred to herein as a "sensor assembly") or a portion thereof, as further described herein. Such a sensor component 103 may include a sensor dock 104 and a sensor hub 106. In some implementations, the system 100 may include the wearable device 102, the sensor dock 104, and the sensor hub 106. As shown in FIGS. 2A-2C, the wearable device 102, the sensor dock 104, and the sensor hub 106 may form a unitary structure configured to be secured to the subject's foot. FIG. 2D illustrates the wearable device 102 and the sensor dock 104 connected to each other, and the sensor hub 106 separated from the wearable device 102 and the sensor dock 104. FIG. 2E illustrates an exploded view of the system 100, illustrating the wearable device 102, the sensor dock 104, and the sensor hub 106 separated from each other. Although the figures illustrate implementations of the system 100 in which the wearable device 102, the sensor dock 104, and the sensor hub 106 are removably connectable to each other, various ones of these components can be integrally formed with each other. For example, in some variations, the wearable device 102 and the sensor dock 104 are integrally formed and removably connectable to the sensor hub 106. As another example, in some variations, the sensor dock 104 and the sensor hub 106 are integrally formed and removably connectable to the wearable device 102.As another example, in some variations, the wearable device 102, the sensor dock 104, and the sensor hub 106 are integrally formed with one another. Implementations of the system 100 in which the wearable device 102 is removably connectable to the sensor dock 104 and / or the sensor hub 106 can advantageously allow wearable devices 102 of various sizes (e.g., small, medium, and large) and / or shapes to be utilized with the system 100, e.g., to accommodate various sizes and / or shapes of the subject's foot 2, ankle 3, heel 4, and / or lower leg 5. In this manner, the system 100 can be customized for the subject 1 by selecting an appropriately configured wearable device 102 while allowing all other aspects of the system 100 (e.g., the sensor dock 104 and the sensor hub 106, etc.) to remain the same and / or be universal for the subjects. In some implementations, the sensor dock 104 and the sensor hub 106 can be advantageously configured to removably connect to one another (e.g., such that the sensor hub 106 can be recharged separately from the sensor dock 104). In some implementations, for example, as shown in FIG. 2E, the sensor dock 104 and the sensor hub 106 form a sensor component 103 that can be removably connected to the wearable device 102.

[0029] As mentioned above, FIG. 2E illustrates an exploded view of the system 100. The wearable device 102 can have a base 160 and a wall 162. The wall 162 can extend from the base 160. For example, the wall 162 can extend from the periphery of the base 160. In some implementations, the wall 162 can extend around a portion of the peripheral edge of the base 160. The base 160 and the wall 162 can form a main body 105 of the wearable device 102. At various places in this disclosure, the "base" and the "wall" can be referred to as being part of the "main body" for ease of reference. However, this is not intended to be limiting or require that a "wearable device" requires a "main body". In some implementations, the wearable device 102 can have a main body 105 and a holder 170 extending outwardly from the main body 105. The main body 105 can include a base 160, an opening 171 in the base 160, and a wall 162 extending from the base 160. In some implementations, the main body 105 additionally includes a wearable device strap 166 (which can also be referred to herein as an “additional strap”) extending from the wall 162. The base 160 (which can also be referred to herein as a “bottom portion”) of the wearable device 102 can be configured to contact a bottom portion of the subject's foot 2 when the system 100 is in use. For example, the base 160 can be configured to contact the heel, arch, ball of the foot, and / or one or more toes of the subject's foot 2. The opening 171 in the base 160 can be configured to be positioned adjacent to a bottom portion of the subject's foot 2 when the system 100 is in use. For example, and as shown, opening 171 can extend through base 160 and can be positioned so that when the wearable device is secured to the subject's foot 2 it underlies the ball of the subject's foot 2.Extending outwardly from the main body portion 105, the holder 170 may extend from the main body portion 105 adjacent the opening 171 in the base 160 and away from a bottom portion of the subject's foot 2 when the system 100 is in use, as shown. The holder 170 may include a cavity 172 configured to removably receive the sensor dock 104 and the sensor hub 106, for example, when the sensor hub 106 is connected to the sensor dock 104. Additionally, the opening 171 may open into the cavity 172 of the holder 170, as shown. The sensor dock 104 may have a main body portion 120 and a sensor strap 130 (also referred to herein as a "strap") connected to and extending from the main body portion 120. The sensor strap 130 of the sensor dock 104 can operably position one or more emitters 104a and one or more detectors 104b of the system 100 and can be configured to be positioned at least partially within and extend outwardly from the opening 171 when the sensor dock 104 is connected to the holder 170. These and other aspects of the system 100 are discussed further below.

[0030] 3 illustrates a schematic diagram of certain features that may be incorporated into the system 100 and any other implementations of the system described herein. FIG. 3 illustrates a sensor dock 104 and a sensor hub 106. As shown, the sensor dock 104 can include one or more emitters 104a, one or more detectors 104b, and one or more temperature sensors 104c. Also shown, the sensor hub 106 can include one or more processors 106a, one or more storage devices 106b, a communication module 106c, a battery 106d, an information element 106e, one or more other sensors 106f, one or more status indicators 106g, and / or a vibration motor 106h.

[0031] The one or more emitters 104a and one or more detectors 104b of the system 100 can be utilized to obtain physiological information indicative of one or more physiological parameters of the subject. These parameters can include various blood analytes such as oxygen, carbon monoxide, methemoglobin, total hemoglobin, glucose, protein, glucose, lipids, percentages (e.g., concentrations or saturations) thereof, etc. The one or more emitters 104a and one or more detectors 104b of the system 100 can also be used to obtain a photoplethysmograph, measures of plethysmograph variability, pulse rate, measures of blood perfusion, etc. Information such as oxygen saturation (SpO2), pulse rate, plethysmographic waveform, respiratory effort index (REI), acoustic respiration rate (RRa), EEG, ECG, pulse arrival time (PAT), perfusion index (PI), pleth variability index (PVI), methemoglobin (MetHb), carboxyhemoglobin (CoHb), total hemoglobin (tHb), and / or glucose can be obtained from the system 100, and data related to such information can be processed by the system 100 and / or transmitted (e.g., via the communication module 106c) to a separate computing device 10 (e.g., a computing device at a caregiver's workstation, a patient monitor, and / or a mobile phone, etc.). The one or more emitters 104a and the one or more detectors 104b can be optically based, for example, utilizing optical radiation. Additionally, one or more emitters 104a can serve as sources of optical radiation that can be directed toward tissue of subject 1 when system 100 is in use. System 100 can include one, two, three, four, five, six, seven, eight or more emitters 104a and / or one, two, three, four, five, six, seven, eight or more detectors 104b.The one or more emitters 104a can be one or more light emitting diodes (LEDs) (e.g., low power high brightness LEDs, etc.), laser diodes, incandescent light bulbs with appropriate frequency selective filters, and / or any other source of optical radiation, and / or any combination thereof, etc. The one or more emitters 104a can emit optical radiation of one or more wavelengths, and can emit visible and near infrared optical radiation. The one or more detectors 104b can be configured to detect the optical radiation generated by the one or more emitters 104a. The one or more detectors 104b can detect optical radiation attenuated through and / or reflected by tissue of the subject 1 (e.g., tissue of the subject's foot 2). The one or more detectors 104b can output one or more signals in response to the detected optical radiation. In some implementations, the one or more detectors 104b can be one or more photodiodes or phototransistors, etc.

[0032] The one or more processors 106a can be configured to process data, execute instructions to perform one or more functions, and / or control operation of the system 100, among other things. For example, the one or more processors 106a can control operation of one or more emitters 104a, one or more detectors 104b, one or more temperature sensors 104c, and / or one or more other sensors 106f of the system 100. As another example, the one or more processors 106a can process signals and / or physiological data received and / or obtained from one or more detectors 104b, one or more temperature sensors 104c, and / or one or more other sensors 106f of the system 100. Furthermore, the one or more processors 106a can execute instructions to perform functions related to storing and / or transmitting such signals and / or physiological data received and / or obtained from one or more detectors 104b and / or one or more other sensors 106f of the system 100. The processor 106a is capable of executing instructions to perform functions associated with storing and / or transmitting any or all such received data.

[0033] The one or more storage devices 106b may include one or more memory devices for storing data, including, without limitation, dynamic and / or static random access memory (RAM), programmable read-only memory (PROM), erasable programmable read-only memory (EPROM), electrically erasable programmable read-only memory (EEPROM), etc. Such stored data may be, for example, processed and / or unprocessed physiological data obtained from the system 100.

[0034] The communication module 106c can facilitate communication (via wire and / or wireless connections) between the system 100 (and / or its components) and separate devices (e.g., separate monitoring devices, computing devices, electrical devices, and / or mobile devices, such as the patient monitor 10a and / or mobile phone 10b shown in FIG. 1C). For example, the communication module 106c can be configured to enable the system 100 to wirelessly communicate with other devices, systems, and / or networks via any of a variety of communication protocols. The communication module 106c can be configured to use any of a variety of wireless communication protocols, such as, for example, Wi-Fi (802.11x), Bluetooth, ZigBee, Z-wave, cellular, infrared, near field communication (NFC), RFID, satellite transmissions, proprietary protocols, and combinations thereof. The communication module 106c can enable data and / or instructions to be transmitted to and / or received from the system 100 and the separate computing devices. The communications module 106c may be configured to transmit (e.g., wirelessly) processed and / or unprocessed physiological parameters, data and / or other information to one or more separate computing devices, which may include, among other things, a patient monitor, a mobile device (e.g., an iOS or Android enabled smartphone, tablet, laptop computer), desktop computer, server, or other computing or processing device for display and / or further processing.Such a separate computing device may be configured to store and / or further process the received physiological parameters, data, and / or other information, may be configured to display information indicative of or derived from the received parameters, data, and / or information, and / or may be configured to transmit information (including displays, alarms, alerts, and notifications) to various other types of computing devices and / or systems that may be associated with a hospital, a caregiver (e.g., primary care provider), and / or a user (e.g., employer, school, friend, family) that has permission to access the subject's data. As another example, the communication module 106c of the system 100 may be configured to wirelessly transmit the processed and / or unprocessed acquired physiological parameters, data, information, and / or other information (e.g., movement and / or location data) to a mobile phone, which may include one or more processors configured to execute an application that generates a graphical user interface that displays information representative of the processed or unprocessed physiological parameters, data, information, and / or other information acquired from the system 100. The communication module 106c may be and / or may include a wireless transceiver. The communication module 106c may be embodied in an antenna and / or an NFC chip.

[0035] The battery 106d can provide power for the hardware components of the system 100 described herein. The battery 106d can be rechargeable. For example, the battery 106d can be a lithium, lithium polymer, lithium ion, lithium ion polymer, lead acid, nickel-cadmium, or nickel metal hydride battery. In some implementations, the battery 106d can be non-rechargeable. Additionally or alternatively, the system 100 can be configured to obtain power from a power source that is external to the system 100. For example, the system 100 can include or be configured to connect to a cable, which can itself connect to an external power source to provide power to the system 100.

[0036] Information element 106e can be a memory storage element that stores in non-volatile memory information used to help maintain standards of quality associated with system 100. Illustratively, information element 106e can store information regarding whether system 100 was previously activated and whether system 100 was previously operational for an extended period of time (e.g., for example, 4 hours, 1 day, 2 days, 5 days, 10 days, 20 days, 1 month, multiple months, or any period of time, etc.). Information stored in information element 106e can be used, for example, to help detect improper reuse of system 100.

[0037] In some implementations, the system 100 may include one or more other sensors 106f. The other sensors 106f may include motion sensors (e.g., including one or more accelerometers and / or gyroscopes) that may be utilized to determine motion of the subject and / or a portion of the subject's body (e.g., foot 2, ankle 3, heel 4, and / or shank 5). In some implementations in which the system 100 (e.g., sensor hub 106) includes motion sensors, the processor 106a may determine whether the subject's foot 2, ankle 3, heel 4, and / or shank 5 is moving, and in response to such a determination, may not receive, process, and / or determine one or more physiological parameters (because such a determination may include inaccuracies due to such motion). The other sensors 106f may be disposed on, disposed within, and / or operably positioned by any one or more of the aspects of the system 100. For example, the other sensors can be disposed on, disposed within, and / or operably positioned by any one or more of the wearable device 102, the sensor dock 104, and / or the sensor hub 106. The other sensors 106f can be operably connected to one or more processors 106a, which can control operation of the other sensors 106f and / or process data received from the other sensors 106f.

[0038] The one or more status indicators 106g can be configured to provide and / or indicate the status of the system 100 and / or the status of one or more physiological parameters of the subject 1 as determined by the system 100 and / or any devices in communication with the system 100. In some implementations, the one or more status indicators 106g can be configured to indicate the status of the system 100, such as, for example, whether the system 100 is in an operational ("on") mode, whether the system 100 is paired or has paired with a separate device, whether an error has been detected, and / or the power level of the system 100 (e.g., the charge of the battery 106d of the sensor hub 106), etc. For example, the one or more status indicators 106g can be configured to illuminate and / or project optical radiation of one or more wavelengths from one or more portions of the system 100. As another example, the one or more status indicators 106g can be configured to illuminate and / or emit optical radiation from one or more portions of the sensor hub 106 of the system 100. The one or more processors 106a may be in communication with the one or more status indicators 106g and may be configured to instruct the one or more status indicators 106g to cause any of such aforementioned status indications and / or illumination.

[0039] In some cases, the one or more status indicators 106g can be configured to provide optical radiation (e.g., light) feedback to the subject when the system 100 is secured to the subject and / or when the sensor hub 106 and the sensor dock 104 are connected together. In some implementations, the system 100 can be configured to trigger optical radiation feedback to the subject 1 (when the system 100 is secured to the subject) in response to one or more physiological parameters determined by the system 100 and / or by any device in communication with the system 100 (e.g., a separate computing and / or mobile device, e.g., a patient monitor, etc.). The one or more processors 106a can instruct the one or more status indicators 106g to emit or stop emitting optical radiation, and / or can instruct the one or more status indicators 106g to change a characteristic of the optical radiation (e.g., increase / decrease optical radiation brightness, change optical radiation wavelength and / or color, change the rate of blinking of optical radiation, etc.) in response to one or more determined physiological parameters. Such actions by the one or more processors 106a can be dynamically tracked over time, for example, with physiological parameter determinations. By way of example, in some implementations, the one or more processors 106a can provide instructions to the one or more status indicators 106g (e.g., such as those discussed above) in response to a condition of a subject using the system 100.For example, if, while a subject is using the system 100, one or more physiological parameters determined by the system 100 and / or any device in communication with the system 100 indicate hypoxemia (low blood oxygen), the one or more processors 106a can instruct the one or more status indicators 106g to produce optical radiation to notify the subject and / or their care provider to restore proper breathing and / or safe blood oxygen levels. As another example, while a subject is using the system 100, if one or more physiological parameters determined by the system 100 and / or any device in communication with the system 100 indicate edema (swelling caused by excess fluid trapped in the body's tissues), the one or more processors 106a can instruct the one or more status indicators 106g to cause optical radiation to be emitted from the system 100 as described above. In some implementations, the one or more processors 106a and / or any device in communication with the system 100 can instruct the one or more status indicators 106g to cause optical radiation to be emitted when a determined subject physiological parameter of interest meets and / or exceeds a set threshold, meets and / or falls below a set threshold, and / or meets, exceeds, and / or falls below a set range. In some cases, the optical radiation emitted from the one or more status indicators 106g can correspond to an alert, alarm, notification, and / or any other situation that may require the subject and / or a care provider to intervene in the subject's care.The one or more status indicators 106g may be positioned in various portions of the system 100 (e.g., in the sensor hub 106) such that optical radiation emitted from the one or more status indicators emits from and / or through holes and / or openings in the sensor hub 106 (e.g., through hole 153 in the sensor hub 106 shown and described in Figures 5A, 5B, and 5C, such as by status indicator 167 shown and described in Figures 5I and 5J).

[0040] The vibration motor 106h can be configured to vibrate one or more portions of the system 100 (e.g., the wearable device 102, the sensor hub 106, and / or the sensor dock 104 when the sensor hub 106 and the sensor dock 104 are coupled together), and it can vibrate one or more portions of the subject's body (e.g., the feet) when the system 100 is secured to the subject. For example, the vibration motor 106h can be configured to vibrate the sensor hub 106 or a portion thereof. The one or more processors 106a can be in communication with the vibration motor 106h and can be configured to instruct the vibration motor 106h to cause any of such aforementioned vibrations.

[0041] In some cases, the vibration motor 106h can be utilized to provide haptic feedback to the subject when the system 100 is secured to the subject. In some implementations, the system 100 can be configured to cause vibrations and / or provide haptic feedback to one or more parts of the subject's body (when the system 100 is secured to the subject) via the vibration motor 106h in response to one or more physiological parameters determined by the system 100 and / or by any device in communication with the system 100 (e.g., a separate computing device, an electrical device, and / or a mobile device, e.g., the patient monitor 10, etc.). The one or more processors 106a can instruct the vibration motor 106h to cause vibrations, to stop vibrating, and / or to change the nature of the vibrations (e.g., increase / decrease vibration speed, increase / decrease vibration intensity, change vibration pattern, etc.) in response to the one or more determined physiological parameters. Such actions by the one or more processors 106a can be tracked dynamically over time, for example, by physiological parameter determinations. By way of example, in some implementations, the one or more processors 106a can provide instructions to the vibration motor 106h (e.g., such as those discussed above) in response to a condition of a subject using the system 100. For example, if one or more physiological parameters determined by the system 100 and / or any devices in communication with the system 100 indicate hypoxemia (low blood oxygen) while the subject is using the system 100, the one or more processors 106a can instruct the vibration motor 106h to vibrate to cause the subject to wake up in an attempt to restore proper breathing and / or safe blood oxygen levels.This can be significantly beneficial when the system 100 is worn by an infant or toddler, where continuous or intermittent monitoring is important. As another example, when a subject is using the system 100, if one or more physiological parameters determined by the system 100 and / or any device in communication with the system 100 indicate edema (swelling caused by excess fluid trapped in the body's tissues), the one or more processors 106a can instruct the vibration motor 106h to cause vibration of a portion of the subject's body (such as, for example, their foot, ankle, heel, lower leg, and / or any other part of the subject's body). In some implementations, the one or more processors 106a and / or any device in communication with the system 100 can instruct the vibration motor 106h to cause vibration if the determined subject physiological parameter of interest meets and / or exceeds a set threshold, meets and / or falls below a set threshold, and / or meets, exceeds, and / or falls below a set range. In some cases, the vibration of the vibration motor 106h can correspond to an alert, an alarm, a notification, and / or any other situation that may require the subject and / or a care provider to intervene in the subject's care. In some implementations, the one or more processors 106a can instruct the vibration motor 106h to vibrate in response to the status of the battery 106d (e.g., when the charge of the battery 106d drops below a certain threshold). In some implementations, the system 100 can include more than one vibration motor 106h (e.g., two, three or more vibration motors 106h). The vibration motors 106h can be positioned in various parts of the system 100 (e.g., in the sensor hub 106).

[0042] 4A-4G illustrate various perspective views of the sensor dock 104 of the system 100. As shown, the sensor dock 104 can have a main body portion 120 and a sensor strap 130 (which can also be referred to herein as a "strap") that is connected to and extends outwardly from the main body portion 120. The main body portion 120 can include a base 128 and an arm 122 that extends outwardly from the base 128. In some implementations, the main body portion 120 further includes a shell 127, which is described further below. The sensor strap 130 can include one or more emitters 104a and one or more detectors 104b, and can be configured to secure the system 100 to the subject's foot 2 (e.g., alone or in combination with a wearable device strap 166 of the wearable device 102), as described further herein. In some implementations, the system 100 includes an emitter package 144 (shown in FIG. 4E) that includes one or more emitters 104a. Similarly, in some implementations, the system 100 includes a detector package 146 (shown in FIG. 4E) that includes one or more detectors 104b. The sensor strap 130 can be configured to receive the emitter package 144 to operably position the one or more emitters 104a. Similarly, the sensor strap 130 can be configured to receive the detector package 146 to operably position the one or more detectors 104b. One or more emitters 104a in the emitter package 144 and one or more detectors 104b in the detector package 146 can be in electrical communication with the electrical connector 124 of the sensor dock 104 via a circuit layer 147 disposed in the sensor strap 130 and via a portion 147c (shown in FIG. 4F) of the circuit layer 147 that extends from the circuit layer 147 in the sensor strap 130 to the electrical connector 124.

[0043] The electrical connector 124 can be configured to releasably electrically connect the sensor dock 104 (and thus the one or more emitters 104a and the one or more detectors 104b) to the sensor hub 106. The sensor dock 104 can also include features for mechanically engaging / connecting with the sensor hub 106. For example and as shown, the arm 122 extending from the base 128 can be configured to releasably mechanically engage / connect with the sensor hub 106. In some implementations, an electrical connector of the sensor hub 106 (e.g., electrical connector 151 shown in FIGS. 5A-5B ) can releasably mechanically and electrically engage / connect with the electrical connector 124 of the sensor dock 104 when the sensor hub 106 is mechanically engaged / connected with the arm 122 of the sensor dock 104.

[0044] As shown in FIGS. 4A-4G, in some implementations, the main body 120 of the sensor dock 104 has a length and / or width that is greater than the height of the sensor dock 104. In some implementations, the sensor dock 104 includes two arms 122. The arms 122 of the sensor dock 104 can extend in the same direction from the base 128 to form a generally U-shaped structure. The arms 122 can be generally parallel to one another such that a gap is formed between the arms 122. Such a gap can be sized to accommodate, for example, the sensor hub 106 and / or at least a portion of the sensor hub 106. In some implementations, the arms 122 are the same length. Moreover, the arms 122 can be mirror images of one another with respect to size, shape, and other characteristics. In some implementations, the sensor dock 104 can include one or more retaining features configured to engage the sensor hub 106. For example, each of the arms 122 of the sensor dock 104 can include a protrusion 123 that is configured to engage with the sensor hub 106, allowing the sensor dock 104 to connect to the sensor hub 106. The protrusion 123 can be disposed along an inner surface of each of the arms 122 such that the protrusion 123 faces toward the sensor hub 106 when the sensor hub 106 is connected to the sensor dock 104. The protrusion 123 can smoothly transition from the inner surface of the arm 122 such that the sensor hub 106 can slidably engage with the protrusion 123. For example, the protrusion 123 can include a ramp-like structure that defines a smooth transition between the inner surface of the arm 122 and a maximum "height" of the protrusion 123. As another example, the protrusion 123 can be rounded, have a rounded tip, and / or have a parabolic cross-section, which allows for a smooth transition with the inner surface of the arm 122.The protrusion 123 can interact with a corresponding recess in the sensor hub 106, which can serve to releasably lock the sensor hub 106 in place by the sensor dock 104. In some implementations, the interaction between the protrusion 123 of the sensor dock 104 and the recess in the sensor hub 106 can provide tactile feedback to the subject indicating a full engagement / connection of the sensor hub 106 and the sensor dock 104. Details of such recess in the sensor hub 106 are described below with respect to FIGS. 5A-5J. Any number of retaining features can be provided on the sensor dock 104 to aid in releasably connecting the sensor hub 106 to the sensor dock 104. In some cases, other types of retaining features can be utilized. For example, an edge of the arm 122 (which can be defined as the transition between the inner surface of the arm 122 and the outer surface of the arm 122) can be configured to aid in the connection between the sensor dock 104 and the sensor hub 106. In some implementations, the arm 122 is sized and shaped to releasably connect to the sensor hub 106. In some cases, the sensor hub 106 slidably connects to the sensor dock 104.

[0045] As discussed above and shown in FIGS. 4A-4B, the sensor dock 104 can include an electrical connector 124. The electrical connector 124 can be configured to releasably electrically and mechanically connect to a corresponding electrical connector of the sensor hub 106 such that, when connected together, the sensor hub 106 is placed in electrical communication with the one or more emitters 104a and the one or more detectors 104b of the system 100. The electrical connector 124 can include any number of pins. For example, with reference to FIGS. 4A-4B, the electrical connector 124 can include eight pins. In some implementations, the electrical connector 124 can include an alternative number of pins. In some implementations, the electrical connector 124 can include a number of openings corresponding to the number of pins of the corresponding electrical connector of the sensor hub 106. 4A-4B , the electrical connector 124 can be disposed on an interior portion of a base 128 of the sensor dock 104 such that it faces the sensor hub 106 when the sensor hub 106 is connected to the sensor dock 104. In some implementations, the sensor dock 104 can include one or more features to aid in aligning the electrical connector 124 with a corresponding electrical connector of the sensor hub 106. For example, the sensor dock 104 can include a wall 126 positioned adjacent the electrical connector 124, and the wall 126 can be configured to aid in releasably connecting the electrical connector 124 with the corresponding electrical connector of the sensor hub 106.

[0046] The base 128 of the sensor dock 104 can include a top portion 128a and a bottom portion 128b (e.g., as shown in FIGS. 4F-4G) that can be integrally formed (or, alternatively, separable from one another). The top portion 128a can include the electrical connector 124 and the wall portion 126, and the bottom portion 128b can include the arm 122. In some implementations, a shell 127 fits over, connects to, and / or is integral with the base 128 and the arm 122. For example, the shell 127 can connect to the base 128 and the arm 122 via a connecting portion 121 disposed on the arm 122. In some cases, the shell 127 is integral with the sensor strap 130, as shown. In some implementations, the main body portion 120 of the sensor dock 104 does not include the shell 127. Main body portion 120 of sensor dock 104 can be configured to connect to a holder 170 of wearable device 102. For example, main body portion 120 of sensor dock 104, including base 128 and arm 122, can be sized and / or shaped to fit within at least a portion of cavity 172 of holder 170.

[0047] The sensor dock 104 may include one or more features to aid in gripping and / or holding the sensor dock 104 (e.g., for gripping and / or holding the sensor dock 104 when connecting and / or disconnecting the sensor hub 106 to the sensor dock 104). For example, the sensor dock 104 may include one or more ribs 125 disposed on a portion of the base 128 (e.g., bottom portion 128b) of the sensor dock 104, the ribs 125 configured to aid in gripping and / or holding the sensor dock 104. The ribs 125 may include a generally linear protrusion that protrudes from a surface of the sensor dock 104 and extends along a portion of the sensor dock opposite where it will contact the wearable device 102 when connected to the holder 170 (e.g., the ribs may be disposed along a “bottom” portion of the sensor dock 104). Alternatively or in addition, in some implementations, the sensor dock 104 may include other features configured to aid in gripping and / or holding the sensor dock 104 (e.g., bumps, a roughened surface texture, etc.).

[0048] As discussed above and shown in FIGS. 4A-4F , the sensor dock 104 can include a sensor strap 130 that connects to and extends outwardly from the main body portion 120 of the sensor dock 104. As shown, and in some implementations, the sensor strap 130 connects to a top of the main body portion 120 of the sensor dock 104 such that the sensor strap 130 is elevated (e.g., forms an elevated surface) relative to the remainder of the sensor dock 104. Moreover, the sensor strap 130 can be disposed at an end of the main body portion 120 adjacent the electrical connector 124. Additionally, the sensor strap 130 can extend from the main body portion 120 in a direction substantially perpendicular to the arm 122 of the sensor dock 104. The sensor strap 130 can be configured to fit within and extend from an opening 171 in the wearable device 102 when the main body portion 120 of the sensor dock 104 is connected to the holder 170 of the wearable device 102 (e.g., when the main body portion 120 of the sensor dock 104 is disposed in the cavity 172 of the holder 170). The portion of the sensor strap 130 that fits within the opening 171 can be configured to form a substantially flush surface (e.g., a substantially coplanar surface) with the base 160 of the wearable device 102 to receive a bottom portion of the subject's foot 2. Additionally, the portion of the sensor strap 130 that extends from the opening 171 can be configured to wrap around at least a portion of the subject's foot to secure the wearable device 102 to the subject's foot 2.

[0049] The strap 130 may include a sensor section 141 and a fixed section 131, as shown in FIGS. 4A and 4C. The sensor section 141 may connect to and extend outwardly from the main body portion 120 of the sensor dock 104, while the fixed section may be disposed at an end 137 of the sensor strap 130 opposite the sensor section 141. The fixed section 141 may include one or more features for securing the system 100 to the subject's foot 2. For example, and as shown, the fixed section 141 may include holes 133 and / or ridges 135 that may interact with one or more features of the wearable device 102 described later herein to secure the system 100 to the subject's foot 2, although other methods of securing may be used. In some implementations, at least a portion of the strap 130 is stretchable. For example, at least a portion of the sensor section 141 and / or at least a portion of the fixed section 131 may be configured to be stretchable.

[0050] 4C-4G illustrate perspective views of the sensor dock 104, which progressively show various aspects, components, and / or features that the sensor dock 104 (e.g., the sensor strap 130) may include. As shown in FIG. 4D, the sensor strap 130 may include a cover 143 (which may also be referred to as a "cover plate") configured to cover the electrical circuitry (e.g., the circuit layer 147, etc.) of the sensor strap 130. The cover 143 may fit into a recess 149a of the sensor strap 130 such that the cover 143 and a surface of the sensor strap 130 adjacent the cover 143 form a substantially flush surface. The cover 143 may include an opening 143a configured to overlie one or more detectors 104b in the detector package 146 and allow optical radiation emitted from one or more emitters 104a in the emitter package 144 to reach the detector. Similarly, the cover 143 can include an opening 143b that is configured to overlie one or more emitters 104a in the emitter package 144 and allow optical radiation emitted from the one or more emitters 104a to pass therethrough. In some implementations, the openings 143a, 143b are covered by a transparent material (e.g., to prevent infiltration of liquid therethrough). However, in alternative implementations, the openings 143a, 143b are uncovered.

[0051] In addition to the cover 143, the sensor strap 130 can include a stiffener 145 configured to increase the stiffness of a portion of the sensor strap 130 positioned in an opening 171 of the wearable device 102 when the sensor dock 104 is connected to the holder 170. The stiffener 145 can be disposed below the cover 143 and can include an opening 145a configured to allow optical radiation to pass therethrough (e.g., so as not to block optical radiation from being emitted by the one or more emitters 104a or optical radiation from being received by the one or more detectors 104b). Also shown in FIG. 4D is a circuit layer 147 that can be disposed below the cover 143 and the stiffener 145 and can fit into a recess 149b (shown in FIGS. 4E-4F) of the sensor strap 130. As mentioned above, the circuit layer 147 can electrically connect the one or more emitters 104a in the emitter package 144 and the one or more detectors 104b in the detector package 146 to the electrical connector 124 of the sensor dock 104. In some implementations, the circuit layer 147 also electrically connects the temperature sensor 104c of the sensor dock 104 to the electrical connector 124. The circuit layer 147 can be configured as a flexible circuit that can bend freely together with the sensor strap 130. In this regard, the circuit layer 147 can have a length that is greater than the distance between where the circuit layer 147 electrically connects to the one or more emitters 104a in the emitter package 144 and the one or more detectors 104b in the detector package 146. For example, the circuit layer 147 can have one or more bends (e.g., can be serpentine).Similar to the openings 143a and 143b in the cover 143, the circuit layer 147 can include openings 147a and 147b that are configured to overlie one or more detectors 104b and one or more emitters 104a, respectively, and allow optical radiation to be received and / or emitted therethrough.

[0052] 4E shows the sensor dock 104 with the cover 143, stiffener 145, and circuit layer 147 removed from the view. This view shows the emitter package 144, the detector package 146, and the temperature sensor 104c in the temperature sensor package 148 positioned by the sensor strap 130. The one or more emitters 104a in the emitter package 144 can be positioned in a first portion of the sensor strap 130 that is outside and / or spaced apart from the opening 171 of the wearable device 102 when the sensor dock 104 is connected to the holder 170. For example, the emitter package 144 can be disposed in a cavity 149c (shown in FIG. 4F) of the sensor strap 130. The one or more detectors 104b in the detector package 146 and the temperature sensor 104c in the temperature sensor package 148 can be positioned in a second portion of the sensor strap 130, which can be positioned in an opening 171 of the wearable device 102 when the sensor dock 104 is connected to the holder 170. The temperature sensor 104c in the temperature sensor package 148 can be positioned proximate to but spaced apart from the one or more detectors 104b in the detector package 146. For example, the detector package 146 and the temperature sensor package 148 can be disposed in a cavity 149d (shown in FIG. 4F) of the sensor strap 130. The sensor section 141 of the sensor strap 130 can include both such first and second portions described above.

[0053] The one or more emitters 104a in the emitter package 144 can be aligned (e.g., vertically aligned) with and / or directed toward the one or more detectors 104b in the detector package 146 when the sensor strap 130 is wrapped around an upper portion of the subject's foot 2 (e.g., as shown in FIG. 1D ). The temperature sensor 104c in the temperature sensor package 148 can be horizontally aligned with the detector package 146 and vertically misaligned with the emitter package 144 when the sensor strap 130 is wrapped around an upper portion of the subject's foot 2 (also shown in FIG. 1D ). In such a position, and with the sensor strap 130 wrapped around an upper portion of the subject's foot 2, the emitter package 144 can be operably positioned against and / or adjacent to the tissue of the upper part of the subject's foot 2, and the detector package 146 and the temperature sensor package 148 can be operably positioned against and / or adjacent to the tissue of the bottom part of the subject's foot 2 (e.g., tissue of the ball of the subject's foot 2). Thus, the detector package 146 can be operably positioned by the sensor strap 130 such that optical radiation emitted from the emitter package 144 can pass through and / or be attenuated by the tissue of the subject's foot 2 before being detected by the detector package 146. In some implementations, the locations of the one or more emitters 104a in the emitter package 144 and the one or more detectors 104b in the detector package 146 can be swapped.In such an implementation, and with the sensor strap 130 wrapped around an upper portion of the subject's foot 2, the detector package 146 can be operably positioned against and / or adjacent to the upper tissue of the subject's foot 2, and the emitter package 144 can be operably positioned against and / or adjacent to the bottom tissue of the subject's foot 2 (e.g., tissue at the ball of the subject's foot 2).

[0054] 4E, the sensor strap 130 may also include a detector shield 132. The detector shield 132 may at least partially surround and / or enclose a detector package 146 including one or more detectors 104b. The detector shield 132 may be configured to suppress, prevent, and / or reduce ambient light, stray light, and / or light emitted from the emitter package 144 that does not pass through tissue from being received by the detector package 146, which may advantageously improve the integrity of the physiological parameter determination. Additionally or alternatively, the detector shield 132 may shield the detector package 146 against and / or with respect to electromagnetic noise. For example, in some implementations, the detector shield 132 may act as a Faraday cage or shield to block electromagnetic fields. The sensor strap 130 may also include an optically transmissive material configured to direct optical radiation toward the detector package 146 after passing through tissue of the subject's foot 2. In some cases, the optically transmissive material can include a lens. In some cases, the optically transmissive material can include a diffuser configured to diffuse, spread, scatter, and / or scatter optical radiation attenuated by tissue before being received by the detector package 146. The optically transmissive material can form part of the detector package 146 or it can be configured to be positioned between the detector package 146 and the tissue of the subject 1 when the system 100 is secured to the subject 1. In some implementations, the optically transmissive material is disposed in an opening 143a of a cover 143 overlying the detector package 146. Similarly, the sensor strap 130 can include an optically transmissive material configured to focus or diffuse optical radiation emitted from the emitter package 144.In some cases, the optically transmissive material can include a lens. In some cases, the optically transmissive material can include a diffuser configured to spread, widen, scatter, and / or scatter the optical radiation emitted from the emitter package 144 before such optical radiation enters the subject's tissue. In some cases, this can allow the optical radiation emitted from the emitter package 144 to pass through a greater amount of tissue, facilitating a more accurate determination of a physiological parameter (such as, for example, any of those discussed herein). The optically transmissive material can form a part of the emitter package 144, or it can be configured to be positioned between the emitter package 144 and the subject's tissue when the system 100 is secured to the subject 1. In some implementations, the optically transmissive material is disposed in an opening 143b of a cover 143 overlying the emitter package 144.

[0055] Advantageously, at least a portion of the sensor strap 130 can be made from a flexible material. For example, at least a portion of the sensor strap 130 can be made from silicone (such as, for example, a medical grade and / or biocompatible silicone), a thermoplastic elastomer (such as, for example, a medical grade and / or biocompatible thermoplastic elastomer), and / or any soft, flexible, stretchy, soft, and / or conformable biocompatible material and / or polymer. The flexible sensor strap 130 can advantageously position the emitter package 144 and the detector package 146 near, against, and / or adjacent to a portion of the subject's body (such as, for example, tissue of the subject's foot 2) for optimal functioning of the system 100. For example, by conforming to the subject's foot 2, the sensor strap 130 can optimally position the emitter package 144 against, adjacent to, and / or near the subject's foot 2 such that optical radiation emitted from the emitter package 144 is directed to / through the subject's foot 2. As another example, by conforming the sensor strap 130 to the subject's foot 2, environmental and / or stray optical radiation and / or optical radiation not produced / emitted by the emitter package 144 can be reduced, eliminated, and / or prevented from being received by the detector package 146. Moreover, a flexible sensor strap 130 can advantageously improve the comfort of the subject 1 when the system 100 is secured to and / or worn by the subject 1. In some implementations, the sensor strap 130 and / or portions thereof can be rigid or semi-rigid. In some cases, the sensor strap 130 can be a composite material and / or a composite of rigid, semi-rigid, and / or flexible / compliant materials.

[0056] In some implementations, the sensor strap 130 can be configured to inhibit, prevent, and / or reduce a predetermined amount of ambient light, stray light, and / or any optical radiation not emitted from the emitter package 144 from reaching the detector package 146. Additionally or alternatively, the sensor strap 130 can be configured to inhibit, prevent, and / or reduce a predetermined amount of optical radiation emitted from the emitter package 144 that has not been attenuated, reflected, and / or passed through the subject's tissue from being received by the detector package 146. In some cases, the sensor strap 130 can be opaque and / or generally light-blocking and / or have a light-blocking coating. In some implementations, the sensor strap 130 can be translucent or transparent. In some implementations, the sensor strap 130 can include portions that are opaque and / or light-blocking and portions that are translucent and / or transparent.

[0057] Figures 5A-5B illustrate perspective views of sensor hub 106, Figure 5C illustrates a bottom view, Figure 5D illustrates a top view, Figures 5E-5F illustrate side views, and Figures 5G-5H illustrate front and back views, respectively. Figures 5I-5J illustrate perspective exploded views of sensor hub 106.

[0058] As shown in FIGS. 5A-5J, the sensor hub 106 can include a first end 150, a second end 152 opposite the first end 150, a first side 154, and a second side 156 opposite the first side 154. The sensor hub 106 can include a length along the sides 154, 156 and / or a width along the ends 150, 152 that is greater than a height of the sensor hub 106. As discussed above with respect to FIG. 3, the sensor hub 106 can include one or more processors 106a, one or more storage devices 106b, a communication module 106c, a battery 106d, an information element 106e, one or more other sensors 106f, one or more status indicators 106g, and / or a vibration motor 106h. As further discussed above, the sensor hub 106 can be configured to releasably mechanically and electrically connect with the sensor dock 104. In this regard, the sensor hub 106 can be sized and / or shaped to releasably mechanically and electrically connect to the sensor dock 104 and / or can include one or more features (e.g., recesses) for releasably mechanically and electrically connecting to the sensor dock 104. In some cases, the sensor hub 106 includes one or more features for engaging with one or more retaining features of the sensor dock 104. For example, in some implementations, the sensor hub 106 includes a recessed portion 158 disposed along at least a portion of the sides 154, 156 that is configured to slidably and releasably mechanically connect with the arm 122 of the sensor dock 104. The recessed portion 158 can extend from the end 150 along the sides 154, 156 toward the end 152 and, in some cases, can terminate adjacent and / or near the end 152. In addition to the recessed portion 158 , the sensor hub 106 can include one or more features for releasably mechanically connecting to the sensor dock 104 .For example, the sensor hub 106 can include a recess 158a, a non-recessed portion 158b, and a recess 158c, which can be disposed along the recessed portion 158 as shown. In some implementations, the recess 158a and the recess 158c can be configured to slidably receive the protrusion 123 of the sensor dock 104 when the recessed portion 158 of the sensor hub 106 slidably engages with the arm 122 of the sensor dock 104. For example, with the sensor hub 106 positioned away from the sensor dock 104 but generally in the same plane as the sensor dock 104, and with the end 150 of the sensor hub 106 facing the sensor dock 104, the sensor hub 106 can be mechanically connected to the sensor dock 104 by aligning the recessed portion 158 with the arm 122 of the sensor dock 104, sliding the sensor hub 106 towards the sensor dock 104 so that the arm 122 engages with the recessed portion 158, continuing to slide the sensor hub 106 towards the sensor dock 104 so that the recess 158a receives the protrusion 123, continuing to slide the sensor hub 106 towards the sensor dock 104 so that the non-recessed portion 158b engages and / or interacts with the protrusion 123, and continuing to slide the sensor hub 106 towards the sensor dock 104 until the recess 158c receives the protrusion 123. In the above example, the interaction between the non-recessed portion 158b of the sensor hub 106 and the protrusion 123 of the sensor dock 104 can provide tactile feedback to the subject (e.g., a "snap" feeling when the non-recessed portion 158b is slid over the protrusion 123). In the case of connecting the sensor hub 106 to the sensor dock 104, such a "snap" feeling can indicate to the subject that the sensor hub 106 is fully connected to the sensor dock 104 once the protrusion 123 slides over the non-recessed portion 158b and the recess 158c receives the protrusion 123.

[0059] 5A-5J , and as discussed above, the sensor hub 106 can include an electrical connector 151 configured to electrically and mechanically connect with a corresponding electrical connector 124 of the sensor dock 104. The sensor hub 106 and its components (e.g., processor 106a and battery 106d, etc.) can be operably connected to one or more emitters 104a and one or more detectors 104b of the system 100 when the electrical connector 151 of the sensor hub 106 is connected to the electrical connector 124 of the sensor dock 104. In some implementations, the electrical connector 151 of the sensor hub 106 can be electrically and mechanically connected to the electrical connector 124 of the sensor dock 104 when the sensor hub 106 is mechanically connected to the sensor dock 104, such as by a connection between the arm 122 of the dock and the recessed portion 158 of the sensor hub 106, as described above. The electrical connector 151 of the sensor hub 106 can include one or more openings configured to receive one or more pins of the corresponding electrical connector 124 of the sensor dock 104. For example, and as shown in FIGS. 5A-5B, the electrical connector 151 of the sensor hub 106 can include eight openings, which are configured to electrically and mechanically connect with corresponding pins of the electrical connector 124 of the sensor dock 104. In some implementations, the electrical connector 151 can include any number of openings. In some implementations, the electrical connector 151 can include one or more pins, which are configured to electrically and mechanically connect with one or more corresponding openings in the electrical connector 124 of the sensor dock 104. As shown in FIGS. 5A-5B, the electrical connector 151 can be disposed on an end 150 of the sensor hub 106 such that, for example, it faces toward the electrical connector 124 of the sensor dock 104 when the sensor hub 106 is connected to the sensor dock 104.In some implementations, the sensor hub 106 can include one or more features to assist in aligning the electrical connector 151 with the corresponding electrical connector 124 of the sensor dock 104. For example, the sensor hub 106 can include a slot 159 adjacent the electrical connector 151 that is configured to releasably receive the wall 126 of the sensor dock 104 and assist in releasably connecting the electrical connector 151 with the corresponding electrical connector 124.

[0060] 5A-5C, 5E-5H, the sensor hub 106 can include one or more features to aid in gripping, holding, moving, and / or sliding the sensor hub 106 (e.g., for sliding the sensor hub 106 when connecting and / or disconnecting the sensor hub 106 from the sensor dock 104). For example, the sensor hub 106 can include one or more ribs 155 disposed on a portion of the sensor hub 106, the ribs 155 configured to aid in gripping, holding, moving, and / or sliding the sensor hub 106. As shown, the ribs 155 can include a generally linear protrusion that protrudes from a surface of the sensor hub 106 and extends at least partially from side 154 to side 156 along a portion of the sensor hub 106 proximate end 152 (e.g., the ribs can be disposed along an outwardly facing portion of the sensor hub 106). Alternatively or in addition, in some implementations, the sensor hub 106 may include other features configured to assist in gripping, holding, moving, and / or sliding the sensor hub 106 (e.g., bumps, roughened surface textures, etc.).

[0061] 5A-5J, and as discussed above, the sensor hub 106 can include one or more status indicators 106g. The one or more status indicators 106g can be configured to emit optical radiation, for example, from and / or through holes and / or openings in the sensor hub 106 (e.g., through holes / openings 153 in the top shell 160 of the sensor hub 106). As shown in FIGS. 5I-5J, the one or more status indicators 106g can include a status indicator 167, which can be an emitter (e.g., an LED) configured to emit optical radiation. The status indicator 167 can be operably coupled to a circuit board (also referred to herein as a "PCB") 163 and the processor 106a of the sensor hub 106. The holes / openings 153 can allow the optical radiation emitted by the status indicators 167 to be visible from a location outside the sensor hub 106 (e.g., by the subject 1 when wearing / using the system 100 and / or by the subject's care provider). In some implementations, the holes / openings 153 can be at least partially aligned with the status indicators 167, allowing the optical radiation emitted from the status indicators 167 to more easily pass through the top shell 160. Additionally or alternatively, the top shell 160 and / or bottom shell 161 of the sensor hub 106 can include a transparent or translucent material that allows the optical radiation emitted from the status indicators 167 to be seen from a location outside the sensor hub 106.

[0062] In some implementations, the sensor hub 106 can include an RFID reader and the sensor dock 104 can include an RFID tag. The RFID tag of the sensor dock 104 can be configured to communicate with the RFID reader of the sensor hub 106. In some implementations, the sensor hub 106 can include an RFID tag and the sensor dock 104 can include an RFID reader. The RFID tag of the sensor hub 106 can be configured to communicate with the RFID reader of the sensor dock 104.

[0063] 5I-5J, components of the sensor hub 106 according to some implementations are shown. As shown, the sensor hub 106 can include a bottom shell 161, a battery 165, a PCB 163, and a top shell 160. In some implementations, the sensor hub 106 can also include a vibration motor 164, a status indicator 167 as described above, and / or a PCB overmolding 162. The vibration motor 164 can be an example implementation of the vibration motor 106h discussed herein and can be configured to provide haptic feedback, vibrations, alerts, notifications, alarms, etc. to the subject 1 and / or their care provider when the system 100 is secured to the subject. The battery 165 can correspond to the battery 106d discussed herein and can be configured to provide power to the system 100. The PCB 163 can include and / or be operably coupled to the processor 106a, the storage device 106b, the communication module 106c, the information element 106e, the status indicator 106g, and the status indicator 167, and / or the vibration motor 106h and the vibration motor 164 previously discussed. The PCB overmolding 162 can be configured to seal the PCB 163, at least a portion of the PCB 163, and / or at least some of the components of the PCB against, for example, water, other liquids, air, dust, contaminants, and the like. The PCB overmolding 162 can also be configured to provide shock and / or drop protection for the PCB 163 and / or its components. The battery 165 can be configured to operably connect to the PCB 163, the components of the PCB 163, and / or the electrical connector 151 of the sensor hub 106.The bottom shell 161 and the top shell 160 can be configured to contain the components of the sensor hub 106 and can be connected / joined to one another (e.g., by ultrasonic welding) to create a housing / shell for the sensor hub 106. As such, the top shell 160 and / or the bottom shell 161 can include one or more features of the sensor hub 106 (e.g., recessed portion 158, recess 158a, non-recessed portion 158b, recess 158c, etc.) that are configured to releasably connect with the sensor dock 104.

[0064] 6A-6D illustrate perspective views of the wearable device 102 of the system 100 of FIGS. 1A-1B according to some implementations of the present disclosure. The wearable device 102 can be configured to receive and support the foot 2, ankle 3, heel 4, and / or lower leg 5 of the subject 1. Moreover, the wearable device 102 can be made of an elastic material. Elasticity can include the ability to return to an original shape after bending, stretching, or being compressed. For example, the wearable device 102 can be made of silicone (e.g., medical grade and / or biocompatible silicone, etc.), thermoplastic elastomer (e.g., medical grade and / or biocompatible thermoplastic elastomer, etc.), and / or any biocompatible material and / or polymer. 2E, the wearable device 102 can have a main body portion 105 that includes a base 160, an opening 171 in the base 160, and a wall portion 162 extending from the base 160. Also, as discussed, and in some implementations, the main body portion 105 additionally includes a wearable device strap 166 extending from the wall portion 162. 6A-6D, the wall 162 of the wearable device 102 may extend upward from the periphery of the base 160 and may include a side portion 162a (which may also be referred to herein as the "side wall portion"), a rear portion 162b (which may also be referred to herein as the "rear wall portion"), and a side portion 162c (which may also be referred to herein as the "side wall portion") that are configured to wrap around and support a portion of the subject's foot 2 (e.g., a side of the subject's foot 2, the subject's ankle 3, the subject's heel 4, and / or the subject's lower leg 5, etc.). The wall 162 may be discontinuous such that it does not surround the entire periphery of the base 160, leaving space for the sensor strap 130 to extend from an opening 171 in the base 160.Moreover, the wall 162 can be discontinuous such that the toes of the subject's foot 2 are not enclosed. The wall 162 can have a variable height as it extends upward from the base. For example, and as shown in FIGS. 6A-6D , the wall 162 can have a maximum height at the rear portion 162b and a reduced height at the side portions 162a and 162c to encircle and support the subject's heel 4. In some implementations, the main body portion 105 of the wearable device 102 can include a number of holes 164 for ventilation and / or to adjust the resiliency of the wearable device 102. For example, the wall 162 and / or the base 160 can have a number of holes 164 therethrough. Moreover, and in some implementations, the main body portion 105 of the wearable device 102 can include an opening 161 configured to receive the heel 4 of the subject's foot 2. The opening 161 may be located in a rear portion 162 b of the wall 162 .

[0065] 6A-6D , the wearable device 102 may also include one or more features for securing to the subject's foot 2. For example, and as shown, the main body portion 105 of the wearable device 102 may include the previously mentioned wearable device strap 166, which may extend outwardly from the wall portion 162, and a protrusion 165 and / or strap loop 163a configured to interact with a hole 168 and / or a ridge 167, respectively, of the wearable device strap 166 positioned adjacent an end 169 of the wearable device strap 166. The wearable device strap 166 may be configured to wrap over a portion of the subject's foot 2, ankle 3, and / or lower leg 5 and secure to the protrusion 165 and / or strap loop 163a. The wearable device strap 166 can extend from the side portion 162a of the wall 162 at a location adjacent to where the wearable device 102 would receive the subject's ankle 3 when secured to the subject 1. Additionally, the wearable device strap 166 can extend from the side portion 162a at an acute angle to the base 160 when viewed from the side of the wearable device 102. The protrusion 165 and / or the strap loop 163a can extend outwardly and generally perpendicularly from the side portion 162c of the wall 162 (e.g., the side of the wall 162 opposite from where the wearable device strap 166 extends therefrom) to interact with the hole 168 and / or the ridge 167 of the wearable device strap 166, respectively. The protrusion 165 may be generally mushroom-shaped and have an enlarged end for releasably securing through a hole 168 of the wearable device strap 166. The strap loop 163a may create a generally elongated opening configured to releasably receive the end 169 and ridge 167 of the wearable device strap 166.Also, main body portion 105 of wearable device 102 can include one or more features for releasably securing sensor strap 130 when sensor dock 104 is connected to holder 170. For example, and as shown, side portion 162c of wall 162 can include another protrusion 165 and / or strap loop 163b (which can be the same as or similar to strap loop 163a), which can interact with hole 133 and / or ridge 135 of sensor strap 130 in a manner similar or identical to how such features interact with wearable device strap 166. To customize the fit of system 100 to the subject's foot 2, wearable device strap 166 and / or sensor strap 130 can be wrapped around the subject's foot 2 and pulled through strap loops 163a and 163b, respectively, and protrusion 165 can be secured through an appropriate hole in the strap (e.g., one of holes 168 and 133, respectively).

[0066] 7A-7K illustrate various views of the charging station 200. 7A-7B illustrate a perspective view of the charging station 200 with the sensor hub 106 described herein removed from the charging station 200, 7C illustrates a top view of the charging station 200 of FIG. 7A, 7D illustrates a bottom view of the charging station 200 of FIG. 7A, 7E-7F illustrate front and back views, respectively, of the charging station 200 of FIG. 7A, 7G-7H illustrate a side view of the charging station 200 of FIG. 7A, 7I-7J illustrate a perspective view of the charging station 200 of FIG. 7A, and 7K illustrates a perspective cross-sectional view through the charging station 200 of FIG. 7A as shown in FIG. 7C.

[0067] The charging station 200 can be configured to releasably mechanically and electrically connect to (e.g., receive) the sensor hub 106. The charging station 200 can charge and / or recharge the battery 165 of the sensor hub 106 when electrically connected to the sensor hub 106. As shown in FIGS. 7A-7K, the charging station 200 (which can also be referred to herein as a “charging base”, “hub”, and / or “base station”) can include a generally cube-like body 206 with a bottom plate 204 (which can also be referred to herein as a “bottom surface”), a top plate 202 (which can also be referred to herein as a “top surface”), a cavity 203, and an electrical connector 210. The body 206 of the charging station 200 can have a rounded square-like cross-section, most clearly seen in the top and bottom views of FIGS. 7C-7D. Charging station 200 may include an indicator 212, an opening 208, one or more speakers, an opening 209, a reset button 214, and other features as further described below. Additionally, charging station 200 may include any one or more of the features described with respect to the schematic diagram of FIG. 3, including one or more processors 106a, one or more storage devices 106b, a communication module 106c, a battery 106d, an information element 106e, one or more other sensors 106f, one or more status indicators 106g, and a vibration motor 106h.

[0068] As shown in FIGS. 7A-7K, bottom plate 204 can connect to body 206 and form a bottom portion of charging station 200. Opening 208 can be disposed on bottom plate 204 to facilitate, for example, communication and / or sound from one or more speakers and / or other indicators disposed in charging station 200 to be transmitted outside charging station 200 (e.g., for a subject to hear and / or be notified). Opening 209 can also be disposed on bottom plate 204 to, for example, allow any foreign objects (liquid, debris, etc.) that may fall into charging station 200 to escape. Charging station 200 can be configured to rest on a surface, such as a table top or the like, and as such, bottom plate 204 can include one or more pads, anti-slip features, etc., and / or be otherwise configured to provide a stable base for charging station 200. The bottom plate 204 can also include an electrical connector 210, which can be disposed along a side of the bottom plate 204 such that it is accessible when the charging station 200 is resting on / against a surface. As shown, the electrical connector 210 can be disposed along a side of the bottom plate 204 at an end of the charging station 200 that is the rear of the charging station 200. In some implementations, the electrical connector 210 can instead be disposed on a portion of the body portion 206 (e.g., a side of the body portion 206 that is the rear end of the charging station 200). The electrical connector 210 can be a connector and / or a charging port (e.g., a USB-C connector / port, etc.), which can be configured to provide power to the charging station 200 when operably connected to a power source.In some implementations, the charging station 200 can include a reset button 214 disposed on the bottom plate 204 that is configured to reset the charging station 200 when pressed and / or held pressed by the subject.

[0069] As further shown, the top plate 202 can connect to the body portion 206 and form an upper portion of the charging station 200. The top plate 202 can be configured as a push button such that a subject can depress a surface of the top plate 202 (e.g., a top-facing surface) to interact with the charging station 200. In some implementations, the surface of the top plate 202 slopes downward toward its center, creating a generally concave surface of the top plate 202. The indicator 212 can be disposed at and / or between the peripheral connection between the top plate 202 and the body portion 206. For example, the indicator 212 can at least partially circumferentially surround the top plate 202 (as shown, the indicator 212 completely circumferentially surrounds the top plate 202). The indicator 212 can be configured to emit optical radiation and / or enable emission of optical radiation. As an example, indicator 212 can include one or more emitters configured to emit optical radiation from charging station 200. As another example, indicator 212 can be made from a transparent, translucent, light-transmitting, and / or partially light-transmitting material that can allow optical radiation from one or more emitters positioned inside charging station 200 to pass through and / or partially pass through. Indicator 212 can be configured to indicate a status of charging station 200 when sensor hub 106 is connected to charging station 200 and / or to indicate a status of sensor hub 106 (e.g., to indicate a charge state of battery 165 of sensor hub 106 (e.g., low charge, medium charge, and / or fully charged, etc.)).

[0070] 7A-7K, the cavity 203 of the charging station 200 can be configured to releasably mechanically receive the sensor hub 106. As such, the cavity 203 can be shaped and sized to receive the sensor hub 106. The cavity 203 can be disposed in and / or defined by an opening in the top plate 202 such that the cavity 203 extends downward from a top surface of the charging station 200 toward a bottom of the charging station 200. The cavity 203 can include one or more features for releasably mechanically connecting to the sensor hub 106. For example, the cavity 203 can include a stem 220 configured to releasably mechanically connect with the sensor hub 106. The stem 220 can releasably mechanically connect with the sensor hub 106 similar to how the arm 122 of the sensor dock 104 can connect with the sensor hub 106. For example, the stem 220 can be disposed on and extend along both sides of the cavity 203 and can slidably fit into the recessed portion 158 of the sensor hub 106 when the sensor hub 106 is slid into the cavity 203. In some implementations, and as shown (e.g., in the top view of FIG. 7C , among others), the cavity 203 can have a variable contour and / or a contour on one side that is different from the contour on the opposite side (e.g., the side not having the stem 220) to ensure and / or assist in proper alignment and placement of the sensor hub 106 with the charging station 200.

[0071] The cavity 203 can include one or more additional and / or alternative features for releasably electrically and mechanically connecting the sensor hub 106 with the charging station 200. With continued reference to FIGS. 7A-7K, the cavity 203 can include an electrical connector 224 configured to electrically and mechanically connect with a corresponding electrical connector 151 of the sensor hub 106. The sensor hub 106 and its components (e.g., processor 106a and battery 106d / 165, etc.) can be operably connected to the charging station 200 and its components (including the electrical connector 210 for receiving power) when the electrical connector 151 of the sensor hub 106 is connected to the electrical connector 224 of the charging station 200. In some implementations, the electrical connector 151 of the sensor hub 106 can be electrically and mechanically connected to the electrical connector 224 of the charging station 200 when the sensor hub 106 is mechanically connected to the charging station 200 (e.g., by a connection between the stem 220 of the charging station and the recessed portion 158 of the sensor hub 106, as described above). In some cases, the sensor hub 106 can be electrically and mechanically connected to the charging station 200 when it is installed inside the cavity 203. The electrical connector 224 of the charging station 200 can include one or more pins (e.g., eight pins as shown in FIGS. 7C and 7K). In some implementations, the electrical connector 224 can include any number of pins. In some implementations, the electrical connector 224 can include one or more openings configured to receive one or more pins of a corresponding electrical connector of the sensor hub 106.7C and 7K, the electrical connector 224 can be disposed in the cavity 203, for example, at a bottom of the cavity 203 such that it faces the sensor hub 106 when the sensor hub 106 is connected to the charging station 200. In some implementations, the charging station 200 can include one or more features to aid in aligning the electrical connector 224 with a corresponding electrical connector of the sensor hub 106. For example, the cavity 203 can include a wall 222 adjacent the electrical connector 224, the wall 222 configured to aid in releasably connecting the electrical connector 224 with the corresponding electrical connector 151 of the sensor hub 106.

[0072] In some implementations, the charging station 200 includes a communication module including an NFC antenna (e.g., in a front side of the body portion 206) for recognizing and / or communicating with other electronic devices and / or sensors. In some implementations, when the sensor hub 106 is mechanically and electrically coupled to the charging station 200 (e.g., when the sensor hub 106 is seated in the cavity 203 of the charging station 200 and the electrical connector 151 of the sensor hub 106 is operably connected to the electrical connector 224 of the charging station 200 (e.g., when the sensor hub 106 is docked with the charging station 200)), the sensor hub 106 can automatically pair with and / or begin electrical communication with the charging station 200. The charging station 200 can charge the battery 165 of the sensor hub 106 when the sensor hub 106 is docked with the charging station 200. Additionally, and in some implementations, the sensor hub 106 can download data (e.g., physiological data from subject 1, etc.) to the charging station 200 and / or via the charging station 200 to a server, another electronic device, the cloud, and / or a wireless or wired network. In some implementations, the charging station 200 can update software on the sensor hub 106 when the sensor hub 106 is docked with the charging station 200.

[0073] In some implementations, the charging station 200 can be configured as an array such that it can releasably electrically and mechanically connect to two or more sensor hubs 106 at a time. For example, the charging station 200 can be configured to have two or more cavities 203 configured to releasably electrically and mechanically connect to two or more sensor hubs 106. In some implementations, the charging station 200 can be configured as a linear array of cavities 203 (e.g., an array of two, three, four, or more cavities). In some cases, the charging station 200 can be configured as an array of cavities 203 with one or more "rows" and one or more "columns." In some implementations, the charging station 200 can be configured to slidably receive the sensor hubs 106 in a vertical orientation (e.g., such as that shown in FIG. 7A). In some implementations, the charging station 200 can be configured to slidably receive the sensor hub 106 in an orientation other than vertical (e.g., at an angle to the vertical, sideways, horizontally, etc.).

[0074] In some implementations, the charging station 200 can include a battery 106d configured as a backup battery to provide power / charging to the sensor hub 106 even when a power source is not available to provide power to the charging station 200. Such a backup battery can be sized / rated and / or have the capacity to provide a partial charge, a full charge, two full charges, three or more full charges, or any amount of partial or full charges to the sensor hub 106 in the event of a power outage.

[0075] 8A-8B illustrate perspective views of another implementation of a system 300 (which may also be referred to herein as a "wearable system," "wearable sensor system," or "wearable physiological sensor system") secured to a subject's foot 2 and configured to measure at least one physiological parameter of the subject 1. The system 300 may be similar or identical to the system 100 in some or many respects. For example, the system 300 may have a wearable device 302, a sensor dock 304, and / or a sensor hub 306, which are similar or identical to the wearable device 102, the sensor dock 104, and the sensor hub 106 of the system 100, respectively, in some or many respects. The system 300 may be secured to the subject's foot 2, ankle 3, heel 4, and / or lower leg 5 in a manner similar or identical to the manner in which the system 100 may be secured to the subject 1. Moreover, the system 300 may include one or more emitters 304a in an emitter package 344, one or more detectors 304b in a detector package 346, and one or more temperature sensors 304c in a temperature sensor package 348, which are similar or identical to the one or more emitters 104a in the emitter package 144, the one or more detectors 104b in the detector package 146, and the one or more temperature sensors 304c in the temperature sensor package 148, respectively, of the system 100. The system 300 may include any of the features or components discussed with respect to FIG. 3 above. The system 300 may wirelessly communicate with one or more separate computing devices (which may be, for example, a patient monitor 10a and / or a mobile phone 10b) via any of a variety of wireless communication protocols (such as, for example, any of those discussed herein with respect to the system 100).Moreover, the system 300 is capable of wirelessly transmitting physiological data and / or physiological parameters of the subject to a separate computing device (e.g., the patient monitor 10a and / or the mobile phone 10b, etc.), as described herein with respect to the system 100.

[0076] 8C illustrates a cross-section of the system 300 of FIGS. 8A-8B secured to a subject's foot 2. As shown, when secured to the subject's foot 2, the system 300 is capable of operably positioning one or more emitters 304a and one or more detectors 304b on either side of the subject's foot 2. Also, as shown, when secured to the subject's foot 2, the system 300 is capable of operably positioning one or more temperature sensors 304c adjacent the bottom of the subject's foot 2.

[0077] 9A-9E illustrate various perspective views of the system 300 of FIG. 8A. The system 300 may include a wearable device 302. The wearable device 302 may be configured to receive and / or secure an electronic device including one or more sensors for monitoring information regarding physiological parameters, movement, and / or location of the subject 1. For example, the wearable device may be configured to receive and / or secure a sensor component 303 (which may also be referred to herein as a "sensor assembly") or a portion thereof, as further described herein. Such a sensor component 303 may include a sensor dock 304 and a sensor hub 306. In some implementations, the system 300 may include the wearable device 302, the sensor dock 304, and the sensor hub 306. As shown in FIGS. 9A-9C, the wearable device 302, the sensor dock 304, and the sensor hub 306 may form a unitary structure configured to be secured to the subject's foot. FIG. 9D illustrates the wearable device 302 and the sensor dock 304 connected to each other, and the sensor hub 306 separated from the wearable device 302 and the sensor dock 304. FIG. 9E illustrates an exploded view of the system 300, illustrating the wearable device 302, the sensor dock 304, and the sensor hub 306 separated from each other. Although the figures illustrate implementations of the system 300 in which the wearable device 302, the sensor dock 304, and the sensor hub 306 are removably connectable to each other, various ones of these components can be integrally formed with each other. For example, in some variations, the wearable device 302 and the sensor dock 304 are integrally formed and removably connectable to the sensor hub 306. As another example, in some variations, the sensor dock 304 and the sensor hub 306 are integrally formed and removably connectable to the wearable device 302.As another example, in some variations, the wearable device 302, the sensor dock 304, and the sensor hub 306 are integrally formed with one another. Implementations of the system 300 in which the wearable device 302 is removably connectable to the sensor dock 304 and / or the sensor hub 306 can advantageously allow wearable devices 302 of various sizes (e.g., small, medium, and large) and / or shapes to be utilized with the system 300, e.g., to accommodate various sizes and / or shapes of the subject's foot 2, ankle 3, heel 4, and / or lower leg 5. In this manner, the system 300 can be customized for the subject 1 by selecting an appropriately configured wearable device 302 while allowing all other aspects of the system 300 (e.g., the sensor dock 304 and the sensor hub 306, etc.) to remain the same and / or be universal for the subjects. In some implementations, the sensor dock 304 and the sensor hub 306 can be advantageously configured to removably connect to one another (e.g., such that the sensor hub 306 can be recharged separately from the sensor dock 304). In some implementations, the sensor dock 304 and the sensor hub 306 form a sensor component 303 that can be removably connected to the wearable device 302, as shown, for example, in FIG.

[0078] As mentioned above, FIG. 9E illustrates an exploded view of the system 300. The wearable device 302 can have a base 360 ​​and a wall 362. The wall 362 can extend from the base 360. For example, the wall 362 can extend from a periphery of the base 360. In some implementations, the wall 362 can extend around a portion of the peripheral edge of the base 360. The base 360 ​​and the wall 362 can form a main body 305 of the wearable device 302. In some implementations, the wearable device 302 can have the main body 305 and a holder 370 extending outwardly from the main body 305. The main body 305 can include the base 360, an opening 371 in the base 360, and a wall 362 extending from the base 360. In some implementations, the main body portion 305 additionally includes a wearable device strap 366 (which may also be referred to herein as an “additional strap”) configured to connect to and extend from the wall portion 362. The base 360 ​​(which may also be referred to herein as a “bottom portion”) of the wearable device 302 may be configured to contact a bottom portion of the subject's foot 2 when the system 300 is in use. For example, the base 360 ​​may be configured to contact the heel, arch, ball, and / or one or more toes of the subject's foot 2. An opening 371 in the base 360 ​​may be configured to be positioned adjacent to a bottom portion of the subject's foot 2 when the system 300 is in use. For example, and as shown, the opening 371 may extend through the base 360 ​​and be positioned to lie under the ball of the subject's foot 2 when the wearable device is secured to the subject's foot 2. Extending outwardly from the main body portion 305 is a holder 370 which, when the system 300 is in use, can extend from the main body portion 305 adjacent the opening 371 in the base 360 ​​and away from the bottom portion of the subject's foot 2, as shown.The holder 370 can include a cavity 372 configured to removably receive the sensor dock 304 and the sensor hub 306, for example, when the sensor hub 306 is connected to the sensor dock 304. Additionally, an opening 371 can open into the cavity 372 of the holder 370, as shown. The sensor dock 304 can have a main body portion 320 and a sensor strap 330 (also referred to herein as a "strap"), where the sensor strap 330 is connected to and extends from the main body portion 320. The sensor strap 330 of the sensor dock 304 can operably position one or more emitters 304a and one or more detectors 304b of the system 300, and can be configured to be positioned at least partially within and extend outwardly from the opening 371 when the sensor dock 304 is connected to the holder 370. These and other aspects of the system 300 are discussed further below.

[0079] 10A-10F illustrate various perspective views of the sensor dock 304 of the system 300. As shown, the sensor dock 304 may have a main body portion 320 and a sensor strap 330 (which may also be referred to herein as a "strap") that is connected to and extends outwardly from the main body portion 320. The main body portion 320 may include a base 328 with an arm 322 that extends outwardly from the base 328. The sensor strap 330 may include one or more emitters 304a and one or more detectors 304b and may be configured to secure the system 300 to the subject's foot 2 (e.g., alone or in combination with a wearable device strap 366 of the wearable device 302) as further described herein. The sensor strap 330 can be configured to receive an emitter package 344 to operably position one or more emitters 304a. Similarly, the sensor strap 330 can be configured to receive a detector package 346 to operably position one or more detectors 304b. The one or more emitters 304a in the emitter package 344 and the one or more detectors 304b in the detector package 346 can be in electrical communication with the electrical connector 324 of the sensor dock 304 via a circuit layer 347 disposed in the sensor strap 330 and via a portion 347c (shown in FIG. 10E) of the circuit layer 347 that extends from the circuit layer 347 in the sensor strap 330 to the electrical connector 324.

[0080] The electrical connector 324 can be configured to releasably electrically connect the sensor dock 304 (and thus the one or more emitters 304a and the one or more detectors 304b) to the sensor hub 306. The sensor dock 304 can also include features for mechanically engaging / connecting with the sensor hub 306. For example, and as shown, the arm 322 extending from the base 328 can be configured to releasably mechanically engage / connect with the sensor hub 306. In some implementations, when the sensor hub 306 is mechanically engaged / connected with the arm 322 of the sensor dock 304, the electrical connector of the sensor hub 306 can releasably mechanically and electrically engage / connect with the electrical connector 324 of the sensor dock 304.

[0081] As shown in FIGS. 10A-10F, in some implementations, the main body portion 320 of the sensor dock 304 has a length and / or width that is greater than the height of the sensor dock 304. In some implementations, the sensor dock 304 includes two arms 322. The arms 322 of the sensor dock 304 can extend in the same direction from the base 328 to form a generally U-shaped structure. The arms 322 can be generally parallel to one another such that a gap is formed between the arms 322. Such a gap can be sized to accommodate, for example, the sensor hub 306 and / or at least a portion of the sensor hub 306. In some implementations, the arms 322 are the same length. Moreover, the arms 322 can be mirror images of one another with respect to size, shape, and other characteristics. In some implementations, the sensor dock 304 can include one or more retaining features configured to engage the sensor hub 306. For example, each of the arms 322 of the sensor dock 304 can include a protrusion 323 that is configured to engage with the sensor hub 306, allowing the sensor dock 304 to connect to the sensor hub 306. The protrusion 323 can be disposed along an inner surface of each of the arms 322 such that the protrusion 323 faces toward the sensor hub 306 when the sensor hub 306 is connected to the sensor dock 304. The arms 322 and protrusions 323 of the sensor dock 304 can be configured similarly or the same as the arms 122 and protrusions 123 of the sensor dock 104. Moreover, the sensor dock 304 (including the arms 322 and protrusions 323) can interact with the sensor hub 306 (which can be similar or the same as the sensor hub 106) in a similar or the same manner that the sensor dock 104 can interact and / or connect with the sensor hub 106 as described herein.

[0082] As discussed above and shown in FIGS. 10A-10B, the sensor dock 304 can include an electrical connector 324. The electrical connector 324 can be configured to releasably electrically and mechanically connect to a corresponding electrical connector of the sensor hub 306 such that, when connected together, the sensor hub 306 is placed in electrical communication with the one or more emitters 304a and the one or more detectors 304b of the system 300. The electrical connector 324 can be disposed on an inner portion of a base 328 of the sensor dock 304 such that it faces the sensor hub 306 when the sensor hub 306 is connected to the sensor dock 304. In some implementations, the sensor dock 304 can include one or more features to assist in aligning the electrical connector 324 with a corresponding electrical connector of the sensor hub 306. For example, the sensor dock 304 can include a wall 326 positioned adjacent to the electrical connector 324, and the wall 326 can be configured to aid in releasably connecting the electrical connector 324 with a corresponding electrical connector of the sensor hub 306. The releasable electrical connection between the sensor dock 304 and the sensor hub 306 can be similar or the same as the releasable electrical connection between the sensor dock 104 and the sensor hub 106 as described herein.

[0083] The base 328 of the sensor dock 304 can include a top portion 328a and a bottom portion 328b (e.g., as shown in FIG. 10F ), which can be integrally formed (or, alternatively, separable from one another). The top portion 328a can include the electrical connector 324 and the wall portion 326, and the bottom portion 328b can include the arm 322. The main body portion 320 of the sensor dock 304 can be configured to connect to a holder 370 of the wearable device 302. For example, the main body portion 320 of the sensor dock 304, including the base 328 and the arm 322, can be sized and / or shaped to fit within at least a portion of a cavity 372 of the holder 370.

[0084] The sensor dock 304 may include one or more features to aid in gripping and / or holding the sensor dock 304 (e.g., to grip and / or hold the sensor dock 304 when connecting and / or disconnecting the sensor hub 306 to the sensor dock 304). For example, the sensor dock 304 may include one or more ribs 325 disposed on a portion of the base 328 (e.g., bottom portion 328b) of the sensor dock 304, the ribs 325 configured to aid in gripping and / or holding the sensor dock 304. The ribs 325 may be similar or the same as the ribs 125 of the sensor dock 104. Alternatively or in addition, in some implementations, the sensor dock 304 may include other features configured to aid in gripping and / or holding the sensor dock 304 (e.g., bumps, a roughened surface texture, etc.).

[0085] As discussed above and shown in FIGS. 10A-10F, the sensor dock 304 can include a sensor strap 330 that connects to and extends outwardly from the main body portion 320 of the sensor dock 304. As shown, and in some implementations, the sensor strap 330 connects to a top of the main body portion 320 of the sensor dock 304 such that the sensor strap 330 is elevated (e.g., forms an elevated surface) relative to the remainder of the sensor dock 304. Moreover, the sensor strap 330 can be disposed at an end of the main body portion 320 adjacent the electrical connector 324. Additionally, the sensor strap 330 can extend from the main body portion 320 in a direction substantially perpendicular to the arm 322 of the sensor dock 304. The sensor strap 330 can be configured to fit into and extend from an opening 371 in the wearable device 302 when the main body portion 320 of the sensor dock 304 is connected to the holder 370 of the wearable device 302 (e.g., when the main body portion 320 of the sensor dock 304 is disposed in the cavity 372 of the holder 370). The portion of the sensor strap 330 that fits into the opening 371 can be configured to form a substantially flush surface (e.g., a substantially coplanar surface) with the base 360 ​​of the wearable device 302 to receive a bottom portion of the subject's foot 2. Additionally, the portion of the sensor strap 330 that extends from the opening 371 can be configured to wrap around at least a portion of the subject's foot to secure the wearable device 302 to the subject's foot 2.

[0086] The strap 330 can include a sensor section 341 and a fixed section 331, as shown in FIGS. 10A and 10C. The sensor section 341 can connect to and extend outwardly from the main body portion 320 of the sensor dock 304, while the fixed section 331 can be disposed at an end 337 of the sensor strap 330 opposite the sensor section 341. The fixed section 331 can include one or more features for securing the system 300 to the subject's foot 2. For example, and as shown, the fixed section 331 can include loops 333 and / or hooks 335 that can interact with one or more features of the wearable device 302 and / or each other, as described later herein, to secure the system 300 to the subject's foot 2, although other methods of securing can be used. In some implementations, at least a portion of the strap 330 is stretchable. For example, at least a portion of the sensor section 341 and / or at least a portion of the fixed section 331 can be configured to be stretchable. In some implementations, the sensor section 341 is more stretchable than the fixed section 331. In some implementations, the sensor section 341 and the fixed section 331 can be configured to releasably connect to one another. For example, the sensor section 341 can include a connector 338 and the fixed section 331 can include a connector 339, each configured to releasably connect to one another. Details of the connectors 338 and 339 are further discussed with respect to FIGS. 11H-11I later herein. In some variations, the sensor section 341 and the fixed section 331 form a unitary strap 330.

[0087] 10C-10F illustrate perspective views of the sensor dock 304, which progressively show various aspects, components, and / or features that the sensor dock 304 (e.g., the sensor strap 330) may include. As shown in FIG. 10D, the sensor strap 330 may include a cover 343 (which is shown as transparent, so that some of the internal aspects of the sensor strap 341 may be seen, which may also be referred to as a "cover plate") configured to cover the electrical circuitry (e.g., circuit layer 347, etc.) of the sensor strap 330. The cover 343 may fit into a recess in the sensor strap 330, such that the cover 343 and a surface of the sensor strap 330 adjacent the cover 343 form a substantially flush surface. The cover 343 can include an opening configured to overlie one or more detectors 304b in the detector package 346 and one or more emitters 304a in the emitter package 344 in a manner similar or the same as the openings 143a and 143b of the cover 143 described herein. In some implementations, such openings are covered by a transparent material (e.g., to prevent ingress of liquid therethrough). However, in alternative implementations, such openings are not covered. As shown in FIG. 10E (in which an aspect of the sensor strap 341 is removed from view), in addition to the cover 343, the sensor strap 330 can include a stiffener 345 configured to increase the stiffness of a portion of the sensor strap 330 positioned in the opening 371 of the wearable device 302 when the sensor dock 304 is connected to the holder 370.The stiffener 345 can be disposed below the cover 343 and can include an opening 345a configured to allow optical radiation to pass therethrough (e.g., so as not to block optical radiation from being emitted by the one or more emitters 304a or from being received by the one or more detectors 304b). Also shown in FIG. 10E is a circuit layer 347 that can be disposed below the cover 343 and the stiffener 345 and can be positioned within the sensor strap 330. As mentioned above, the circuit layer 347 can electrically connect the one or more emitters 304a in the emitter package 344 and the one or more detectors 304b in the detector package 346 to the electrical connector 324 of the sensor dock 304. In some implementations, the circuit layer 347 also electrically connects one or more temperature sensors 304c (which may be disposed in a temperature sensor package 348) of the sensor dock 304 to the electrical connector 324. The circuit layer 347 may be configured as a flexible circuit that is free to bend along with the sensor strap 330. Similar to the openings in the cover 343, the circuit layer 347 may include openings 347a and 347b that are configured to overlie the one or more detectors 304b and the one or more emitters 304a, respectively, and allow optical radiation to be received and / or emitted therethrough.

[0088] 10E , the emitter package 344, the detector package 346, and one or more temperature sensors 304c in the temperature sensor package 348 of the sensor strap 330 are shown. The one or more emitters 304a in the emitter package 344 can be positioned in a first portion of the sensor strap 330 that is outside and / or spaced apart from the opening 371 of the wearable device 302 when the sensor dock 304 is connected to the holder 370. The one or more detectors 304b in the detector package 346 and the one or more temperature sensors 304c in the temperature sensor package 348 can be positioned in a second portion of the sensor strap 330 that can be positioned in the opening 371 of the wearable device 302 when the sensor dock 304 is connected to the holder 370. The one or more temperature sensors 304c in the temperature sensor package 348 may be positioned proximate to, but spaced apart from, the one or more detectors 304b in the detector package 346. The sensor section 341 of the sensor strap 330 may include both such first and second portions as described above.

[0089] The one or more emitters 304a in the emitter package 344 can be aligned (e.g., vertically aligned) with and / or directed toward the one or more detectors 304b in the detector package 346 when the sensor strap 330 is wrapped around an upper portion of the subject's foot 2 (e.g., as shown in FIG. 8C ). The temperature sensor 304c in the temperature sensor package 348 can be horizontally aligned with the detector package 346 and vertically misaligned with the emitter package 344 when the sensor strap 330 is wrapped around an upper portion of the subject's foot 2 (also shown in FIG. 8C ). In such a position, and with the sensor strap 330 wrapped around an upper portion of the subject's foot 2, the emitter package 344 can be operably positioned against and / or adjacent to the tissue of the upper part of the subject's foot 2, and the detector package 346 and the temperature sensor package 348 can be operably positioned against and / or adjacent to the tissue of the bottom part of the subject's foot 2 (e.g., tissue of the ball of the subject's foot 2). Thus, the detector package 346 can be operably positioned by the sensor strap 330 such that optical radiation emitted from the emitter package 344 can pass through and / or be attenuated by the tissue of the subject's foot 2 before being detected by the detector package 346. In some implementations, the locations of the one or more emitters 304a in the emitter package 344 and the one or more detectors 304b in the detector package 346 can be swapped.In such an implementation, and with the sensor strap 330 wrapped around an upper portion of the subject's foot 2, the detector package 346 can be operably positioned against and / or adjacent to the upper tissue of the subject's foot 2, and the emitter package 344 can be operably positioned against and / or adjacent to the bottom tissue of the subject's foot 2 (e.g., tissue at the ball of the subject's foot 2).

[0090] 10E, the sensor strap 330 can also include a detector shield 332. The detector shield 332 can at least partially surround and / or enclose a detector package 346 including one or more detectors 304b. The detector shield 332 can be configured to suppress, prevent, and / or reduce ambient light, stray light, and / or light emitted from the emitter package 344 that does not pass through tissue from being received by the detector package 346, which can advantageously improve the integrity of the physiological parameter determination. Additionally or alternatively, the detector shield 332 can shield the detector package 346 against and / or with respect to electromagnetic noise. For example, in some implementations, the detector shield 332 can act as a Faraday cage or shield to block electromagnetic fields. The sensor strap 330 may also include an optically transmissive material configured to direct the optical radiation toward the detector package 346 after passing through the tissue of the subject's foot 2. In some cases, the optically transmissive material may include a lens. In some cases, the optically transmissive material may include a diffuser configured to diffuse, spread, scatter, and / or scatter the optical radiation that is attenuated by the tissue before being received by the detector package 346. The optically transmissive material may form part of the detector package 346 or it may be configured to be positioned between the detector package 346 and the tissue of the subject 1 when the system 300 is secured to the subject 1. In some implementations, the optically transmissive material is disposed in an opening in a cover 343 that overlies the detector package 346. Similarly, the sensor strap 330 can include an optically transmissive material configured to focus or diffuse the optical radiation emitted from the emitter package 344. In some cases, the optically transmissive material can include a lens.In some cases, the optically transmissive material can include a diffuser configured to spread, widen, scatter, and / or scatter optical radiation emitted from the emitter package 344 before such optical radiation enters the subject's tissue. In some cases, this can allow the optical radiation emitted from the emitter package 344 to pass through a greater amount of tissue, facilitating a more accurate determination of a physiological parameter (such as, for example, any of those discussed herein). The optically transmissive material can form a part of the emitter package 344, or it can be configured to be positioned between the emitter package 344 and the subject's tissue when the system 300 is secured to the subject 1. In some implementations, the optically transmissive material is disposed within an opening in a cover 343 that overlies the emitter package 344.

[0091] Advantageously, at least a portion of the sensor strap 330 can be made from a flexible material. For example, at least a portion of the sensor strap 330 can be made from silicone (such as, for example, a medical grade and / or biocompatible silicone), a thermoplastic elastomer (such as, for example, a medical grade and / or biocompatible thermoplastic elastomer), and / or any soft, flexible, stretchy, soft, and / or conformable biocompatible material and / or polymer. The flexible sensor strap 330 can advantageously position the emitter package 344 and the detector package 346 near, against, and / or adjacent to a portion of the subject's body (such as, for example, tissue of the subject's foot 2) for optimal functioning of the system 300. For example, by conforming to the subject's foot 2, the sensor strap 330 can optimally position the emitter package 344 against, adjacent to, and / or near the subject's foot 2 such that optical radiation emitted from the emitter package 344 is directed to / through the subject's foot 2. As another example, by conforming the sensor strap 330 to the subject's foot 2, environmental and / or stray optical radiation and / or optical radiation not produced / emitted by the emitter package 344 can be reduced, eliminated, and / or prevented from being received by the detector package 346. Moreover, a flexible sensor strap 330 can advantageously improve the comfort of the subject 1 when the system 300 is secured to and / or worn by the subject 1. In some implementations, the sensor strap 330 and / or portions thereof can be rigid or semi-rigid. In some cases, the sensor strap 330 can be a composite material and / or a composite of rigid, semi-rigid, and / or flexible / compliant materials.

[0092] In some implementations, the sensor strap 330 can be configured to inhibit, prevent, and / or reduce a predetermined amount of ambient light, stray light, and / or any optical radiation not emitted from the emitter package 344 from reaching the detector package 346. Additionally or alternatively, the sensor strap 330 can be configured to inhibit, prevent, and / or reduce a predetermined amount of optical radiation emitted from the emitter package 344 that has not been attenuated, reflected, and / or passed through the subject's tissue from being received by the detector package 346. In some cases, the sensor strap 330 can be opaque and / or generally light-blocking and / or have a light-blocking coating. In some implementations, the sensor strap 330 can be translucent or transparent. In some implementations, the sensor strap 330 can include opaque and / or light-blocking portions and translucent and / or transparent portions.

[0093] 11A-11E illustrate perspective views of the wearable device 302 of the system 300 of FIGS. 8A-8B according to some implementations of the present disclosure. The wearable device 302 can be configured to receive and support the foot 2, ankle 3, heel 4, and / or lower leg 5 of the subject 1. Moreover, the wearable device 302 can be made of an elastic material similar or the same as the wearable device 102 described herein. As discussed with respect to FIG. 9E, the wearable device 302 can include a main body portion 305 including a base 360, an opening 371 in the base 360, and a wall portion 362 extending from the base 360. Also, as discussed, and in some implementations, the main body portion 305 additionally includes a wearable device strap 366 configured to connect to and extend from the wall portion 362. As shown in FIGS. 11A-11E, the wall portion 362 of the wearable device 302 can extend upwardly from the periphery of the base 360 ​​and can include a side portion 362a (which can also be referred to herein as the “side wall portion”), a rear portion 362b (which can also be referred to herein as the “rear wall portion”), and a side portion 362c (which can also be referred to herein as the “side wall portion”) that are configured to wrap around and support a portion of the subject's foot 2 (e.g., a side of the subject's foot 2, the subject's ankle 3, the subject's heel 4, and / or the subject's lower leg 5, etc.). The wall 362 can be discontinuous such that it does not surround the complete periphery of the base 360, leaving space for the sensor strap 330 to extend from an opening 371 in the base 360. Additionally, the wall 362 can be discontinuous such that the toes of the subject's foot 2 are not enclosed. The wall 362 can have a variable height as it extends upward from the base.For example, and as shown in FIGS. 11A-11E , the wall 362 may have a maximum height at the rear portion 362b and a reduced height at the side portions 362a and 362c to surround and support the heel 4 of the subject. In some implementations, the main body portion 305 of the wearable device 302 may include a plurality of holes 364 for ventilation and / or to adjust the resiliency of the wearable device 302. For example, the wall 362 and / or the base 360 ​​may have a plurality of holes 364 therethrough. Additionally, and in some implementations, the main body portion 305 of the wearable device 302 may include an opening 361 positioned in the rear portion 362b of the wall 362. The opening 361 may be configured to allow the wearable device 302 to conform to the heel 4 of the foot 2 of the subject.

[0094] 11A-11E, the wearable device 302 may also include one or more features for securing to the subject's foot 2. For example, and as shown, the main body portion 305 of the wearable device 302 may include the previously mentioned wearable device strap 366, which may connect to and extend outwardly from the wall portion 362, and a strap slot 363a configured to interact with the wearable device strap 366. The wearable device strap 366 may be configured to wrap over a portion of the subject's foot 2, ankle 3, and / or lower leg 5, with an end 369 thereof placed through the strap slot 363a (which may also be referred to herein as an "opening"), and secure back onto itself via interaction between a hook 367 and a loop 368 of the wearable device strap 366. The wearable device strap 366 can connect to and extend from the side portion 362a of the wall 362 at a location adjacent to where the wearable device 302 would receive the subject's ankle 3 when secured to the subject 1. Additionally, the wearable device strap 366 can connect to and extend from the side portion 362a at an acute angle to the base 360 ​​when viewed from the side of the wearable device 302. The strap slot 363a can include a slot through the side portion 362c of the wall 362 (e.g., the side of the wall 362 opposite where the wearable device strap 366 connects to and extends from), which is configured to receive the wearable device strap 366 therethrough. In some implementations, the wearable device strap 366 can be configured to releasably connect to the wall 362. For example, the wearable device strap 366 can include a connector 376 and the wall portion 362 (e.g., side portion 362a) can include a connector 375, each configured to releasably connect to one another.Details of connectors 376 and 375 are discussed further later in this specification with respect to Figures 11F-11G. In some implementations, the wearable device strap 366 is integrally formed with the wearable device 302.

[0095] The main body portion 305 of the wearable device 302 can also include one or more features for releasably securing to the sensor strap 330 when the sensor dock 304 is connected to the holder 370. For example, and as shown, the base 360 ​​can include a portion adjacent an opening 371 that extends beyond where the bottom of the subject's foot 2 is received when the system 300 is worn, which includes a strap slot 363b (which can be the same as or similar to strap slot 363a, which can also be referred to herein as an "opening") that can interact with the sensor strap 330 in a similar or identical manner to how the strap slot 363a interacts with the wearable device strap 366. To customize the fit of the system 300 to the subject's foot 2, the wearable device strap 366 and / or the sensor strap 330 can be wrapped over the subject's foot 2, and the strap ends 369 and 337 can be placed through the strap slots 363a and 363b, and the ends 369 and 337 can be secured back on themselves via interaction between the hooks 367 and 335 and the loops 368 and 333, respectively. In some implementations, the portion of the base 360 ​​that includes the strap slots 363b can deform (e.g., it can bend and / or fold relative to the foot 2) when the sensor strap 330 is secured in the strap slots 363b (e.g., such as that shown in FIGS. 8A-8B ).

[0096] 11F-11G illustrate perspective views of a connector 375 of the wearable device strap 366 and a connector 376 of the wall 362 of the system 300, according to some implementations of the present disclosure. As shown, the connector 375 can be in the form of an elongated cylinder with enclosed rounded ends and can protrude lengthwise from the wall 362 (e.g., side portion 362a of the wall 362). The connector 376 can be in the form of an elongated cylinder with an open end, a closed end, and an open side, which is disposed at the end of the wearable device strap opposite the end 369 and is configured to slidably and releasably connect onto the connector 375. To assist in securing the connectors 375 and 376 together, the connector 375 can include a ramp-like protrusion 375a, which is configured to fit into a corresponding opening 376a in the connector 376. In some implementations, connectors 375 and 376 may be interchanged (e.g., connector 375 may be positioned on wearable device strap 366 and connector 376 may be positioned on wall 362). Alternatively, connectors 375 and 376 may be omitted and wearable device strap 366 may extend from wall 362 (e.g., similar to wearable device strap 166).

[0097] 11H-11I illustrate perspective views of connectors 338 and 339 of sensor strap 330 of system 300, according to some implementations of the present disclosure. As shown, connector 338 can be in the form of an elongated cylinder with an enclosed rounded end and can extend lengthwise from an end of sensor section 341 opposite where sensor section 341 connects to main body portion of sensor dock 304. Connector 339 can be in the form of an elongated cylinder with an open end, a closed end, and an open side, disposed at an end of fixation section opposite end 337 and configured to slidably and releasably connect onto connector 338. To aid in securing connectors 338 and 339 together, connector 338 can include a ramp-like protrusion 338a configured to fit into a corresponding opening 339a in connector 339. In some implementations, connectors 338 and 339 can be interchanged (e.g., connector 338 can be positioned on fixed section 331 and connector 339 can be positioned on sensor section 341 of sensor strap 330). Alternatively, connectors 338 and 339 can be omitted and fixed section 331 can extend from sensor section 341 as a unitary body (e.g., similar to sensor strap 130).

[0098] 12A-12B illustrate perspective views of another implementation of a system 400 (which may also be referred to herein as a "wearable system," "wearable sensor system," or "wearable physiological sensor system") secured to a subject's foot 2 and configured to measure at least one physiological parameter of the subject 1. System 400 may have similar and / or identical features, aspects, functionality, and / or components as any of the systems described herein (e.g., systems 100, 300, and / or any variations thereof). For example, system 400 may have a wearable device 402 that is configured the same or similarly in some or many respects as wearable device 102 and / or wearable device 302. As another example, system 400 may include a sensor hub 404 and a sensor strap 430 (which may be referred to as a sensor component 403), which are configured similarly to sensor component 103, and / or sensor hub 106, sensor dock 104, and sensor strap 130, and / or sensor component 303, and / or sensor hub 306, sensor dock 304, and sensor strap 330 (e.g., sensor hub 404 and sensor strap 430 may combine any and / or all aspects of sensor hub 106, 306, sensor dock 104, 304, and sensor strap 130, 330, and / or sensor assembly 103, 303). In contrast to separate sensor docks 104, 304 and sensor hubs 106, 306, in this implementation, the system 400 may include a sensor hub 404 with a sensor strap 430, and the sensor hub 404 and the sensor strap 430 may include any of the functionality described with respect to the sensor assemblies 103 and 303 of the systems 100 and 300.The system 400 can be secured to the subject's foot 2, ankle 3, heel 4, and / or lower leg 5 in a manner similar or identical to the manner in which the system 100, 300 can be secured to the subject 1. Moreover, the system 400 can include one or more emitters 404a in an emitter package, one or more detectors 404b in a detector package, and one or more temperature sensors 404c in a temperature sensor package, which are similar or identical to one or more emitters 104a, 304a in an emitter package 144, 344, one or more detectors 104b, 304b in a detector package 146, 346, and one or more temperature sensors 104c, 304c in a temperature sensor package 148, 348 of the system 100, 300, respectively. The system 400 can include any of the features or components discussed with respect to FIG. 3 above. The system 400 can wirelessly communicate with one or more separate devices (which can be, for example, a patient monitor 10a, a cell phone 10b, a camera, a hub, or any other separate device described herein) via any of a variety of wireless communication protocols (such as, for example, any of those discussed herein with respect to the systems 100, 300). Moreover, the system 400 can wirelessly transmit physiological data and / or physiological parameters of the subject to a separate device (such as, for example, a patient monitor 10a, a cell phone 10b, a camera, a hub, or other separate device) as described herein with respect to the systems 100, 300.

[0099] FIG. 12C illustrates a cross-section of the system 400 of FIGS. 12A-B secured to a subject's foot 2. As shown, when secured to the subject's foot 2, the system 400 can operably position one or more emitters 404a and one or more detectors 404b generally on either side of the subject's foot 2. For example, the system 400 can position one or more emitters 404a and one or more detectors 404b such that at least some of the optical radiation emitted by the one or more emitters 404a passes through tissue of the subject 1 before being detected by the one or more detectors 404b. The system 400 can position one or more emitters 404a adjacent to a top of the subject's foot 2 and / or adjacent to a side of the subject's foot 2, and can position one or more detectors 404b adjacent to a bottom of the subject's foot 2. In other words, the emitter(s) 404a and the detector(s) 404b do not need to be vertically aligned with one another and on different sides of the subject's foot for the system 400 to operate. In some implementations, the positioning of the emitter(s) 404a and the detector(s) 404b can be reversed. In some implementations, at least a portion of the sensor strap 430 and / or at least a portion of the sensor hub 404 operably positions the emitter(s) 404a and / or the detector(s) 404b as described. In some implementations, at least a portion of the sensor component 403 operably positions the emitter(s) 404a and / or the detector(s) 404b as described.As also shown in FIG. 12C, system 400 is capable of operably positioning thermally conductive probe 445b, which is configured to transmit thermal energy adjacent to the bottom of the subject's foot (e.g., so that it is in contact with the skin of subject 1) and to transmit thermal energy from the bottom of the subject's foot towards temperature sensor 404c.

[0100] 13A-13E illustrate various perspective views of the system 400 of FIGS. 12A-12B. The system 400 may include a wearable device 402. The wearable device 402 may be configured to receive and / or secure an electronic device including one or more sensors for monitoring information regarding physiological parameters, movement, and / or location of the subject 1. For example, the wearable device may be configured to receive and / or secure a sensor component 403 (which may also be referred to herein as a "sensor assembly") or a portion thereof, as further described herein. Such a sensor component 403 may include a sensor hub 404 and a sensor strap 430. In some implementations, the system 400 may include the wearable device 402, the sensor hub 404, and the sensor strap 430. As shown in FIGS. 13A-13C, the wearable device 402 and the sensor component 403 may form a unitary structure configured to be secured to the subject's foot. FIG. 13D illustrates the sensor component 403 separated from the wearable device 402. FIG. 13E illustrates an exploded view of the system 400. The wearable device 402 may have a wearable device strap 466 configured the same as or similar to the wearable device strap 366 of the wearable device 302, and as shown in FIG. 13E, the wearable device strap 466 may be removably connectable to the wearable device 402 (although in some implementations, the wearable device strap 466 may be integrally formed with the wearable device 402). Also shown in FIG. 13E, the sensor component 403 may include a sensor hub 404 and a sensor strap 430, with at least a portion of the sensor strap (e.g., a fixed section) configured to be removably connectable thereto.Although the figures illustrate implementations of system 400 where wearable device 402 and sensor hub 404 and sensor strap 430 are removably connectable to one another (or, in other words, wearable device 402 and sensor component 403 are removably connectable to one another), various of these components can be integrally formed with one another. For example, in some variations, wearable device 402 and sensor hub 404 are integrally formed and removably connectable to sensor strap 430, or at least a portion thereof. As another example, in some variations, sensor hub 404 and sensor strap 430 are integrally formed and removably connectable to wearable device 402. As another example, in some variations, wearable device 402, sensor hub 404, and sensor strap 430 are integrally formed with one another (or, in other words, wearable device 402 and sensor component 403 are integrally formed with one another). Implementations of the system 400 in which the wearable device 402 is removably connectable to the sensor hub 404 and / or sensor strap 430 can advantageously allow wearable devices 402 of various sizes (e.g., small, medium, and large) and / or shapes to be utilized with the system 400, e.g., to accommodate various sizes and / or shapes of the subjects' feet 2, ankles 3, heels 4, and / or lower legs 5. In this manner, the system 400 can be customized for the subject 1 by selecting an appropriately configured wearable device 402 while allowing all other aspects of the system 400 (e.g., the sensor hub 404 and sensor strap 430 or sensor components 403, etc.) to remain the same and / or be universal for subjects.13E , the sensor hub 404 and the sensor strap 430 form a sensor component 403 that can be removably connected to the wearable device 402. In some implementations, at least a portion (e.g., a fixed portion) of the sensor strap 430 and / or the wearable device strap 466 can come in a variety of sizes and / or lengths (e.g., small, medium, large) to advantageously provide a customized fit with any of the various sizes of wearable device 402.

[0101] 14A-14G illustrate various perspective views of a sensor component 403 and / or components / aspects thereof of the system 400. As shown, the sensor component 403 can include a sensor hub 404 having a main body portion 420 and a sensor strap 430 (which may also be referred to herein as a "strap") that is connected to and extends outwardly from the main body portion 420. The main body portion 420 can include a generally rounded rectangular housing having a top, sides, and a bottom. In some implementations, the main body portion 420 of the sensor hub 404 has a length and / or width that is greater than the height of the sensor hub 404. The sensor strap 430 can include one or more emitters 404a and / or one or more detectors 404b and can be configured to secure the system 400 to the subject's foot 2 (e.g., alone or in combination with the wearable device strap 466 of the wearable device 402) as described herein. The sensor strap 430 can be the same as or similar to the sensor straps 130 and / or 330 described herein or can include any of the functionality and / or features of the sensor straps 130 and / or 330. The sensor strap 430 can be configured to operably position the one or more emitters 404a. Similarly, the sensor strap 430 can be configured to operably position the one or more detectors 404b. In some implementations, the sensor hub 403 is configured to operably position the one or more detectors 404b. Moreover, in some implementations (not shown) in which one or more detectors 404b are positioned by a sensor strap 430, one or more emitters 404a can be operably positioned by the sensor hub 404.The one or more emitters 404a and the one or more detectors 404b can be in electrical communication with one or more processors of the sensor hub 404 via a circuit layer 447 that is disposed at least partially within the sensor strap 430 and at least partially within the sensor hub 404 (e.g., as shown in FIG. 14E ). The sensor strap 430 can have a top that sits substantially flush (e.g., substantially coplanar) with (e.g., with) the main body portion 420 of the sensor hub 404. Additionally, the sensor strap 430 can extend from the main body portion 420 in a direction that is substantially perpendicular to the main body portion 420.

[0102] The sensor hub 404 can include an electrical connector 424 configured to releasably connect to a charger 499 and provide power to the sensor hub 404 and / or the sensor strap 430 (e.g., the sensory assembly 403) and any rechargeable batteries therein. In some implementations, the charger 499 can be releasably connected to the electrical connector 424 of the sensor hub 404 with the assistance of one or more magnets. In some implementations (not shown), the charger 499 can connect to an electrical port (e.g., a micro USB-C port, etc.) of the sensor hub 404. The electrical connector 424 can be disposed at a bottom of the sensor hub 404. The sensor hub 404 can also include a status indicator 425 configured to indicate a status of the sensor hub 404, the sensor strap 430, and / or the sensor component 403. The status indicator 425 may be disposed on the bottom of the sensor hub 404 and may be configured similarly or identically to any of the status indicators described herein.

[0103] The strap 430 may include a sensor section 441 and a fixed section 431, as shown at least in FIGS. 14A-14C. The sensor section 441 and the fixed section 431 may be similar or the same as the sensor section 341 and the fixed section 331 of the sensor strap 330 described herein. The sensor section 441 may connect to and extend outwardly from the main body portion 420 of the sensor hub 404, while the fixed section 431 may be disposed at an end of the sensor strap 430 opposite the sensor section 441. The fixed section 431 may include one or more features for securing the system 400 to the subject's foot 2, similar or the same as the fixed section 331 of the sensor strap 330. In some implementations, the sensor section 441 and the fixed section 431 can be configured to releasably connect to one another, for example, via connectors 438, 439, which can be similar or identical to connectors 338, 339 as described elsewhere herein. In some implementations, at least a portion of the strap 430 is stretchable. For example, at least a portion of the sensor section 441 and / or at least a portion of the fixed section 431 can be configured to be stretchable. In some implementations, the sensor section 441 is more stretchable than the fixed section 431.

[0104] 14D-14G illustrate perspective views of the sensor hub 404 and the sensor strap 430, which progressively show various aspects, components, and / or features that the sensor hub 404 and the sensor strap 430 may include. The sensor hub 404 and the sensor strap 430 may include any or all of the features and / or functionality of the sensor hub 306, the sensor dock 304, and the sensor strap 330 described herein. As shown in FIG. 14D, the sensor hub 440 and the sensor strap 430 may include a cover 443 (which may also be referred to as a "cover plate") configured to cover at least a portion of the electrical circuitry of the sensor hub 404 and the sensor strap 430 (e.g., circuit layer 447, etc.). The cover 443 may be similar or the same as the cover 343 described herein. The cover 443 can fit into recesses in the sensor hub 404 and the sensor strap 430 such that the cover 443 and surfaces of the sensor hub 404 and the sensor strap 430 adjacent the cover 443 form a substantially flush surface. The cover 443 can include openings configured to overlie one or more detectors 404b and one or more emitters 404a, similar or identical to the openings 143a, 343a and 143b, 343b of the covers 143, 343 described herein. In some implementations, such openings are covered by a transparent material (e.g., to prevent ingress of liquid therethrough). However, in alternative implementations, such openings are not covered.14E (in which an aspect of the sensor strap 441 has been removed from the view), in addition to the cover 443, the sensor hub 404 and / or strap 430 can include a stiffener 445 (which can be, for example, a plate made from metal) configured to increase the stiffness of a portion of the sensor hub 404 and / or strap 430 positioned adjacent the bottom of the subject's foot when the sensor hub 404 is connected to the wearable device 402. The stiffener 445 can be disposed below the cover 443 and can include an opening 445a configured to allow optical radiation to pass therethrough (e.g., so as not to block optical radiation from being emitted by the one or more emitters 404a or optical radiation from being received by the one or more detectors 404b). As shown, the stiffener 445b can include the thermally conductive probe 445b described above, which is configured to transmit thermal energy from the bottom of the subject's foot toward the temperature sensor 404c. The thermally conductive probe 445b can be configured as a rounded protrusion that protrudes from the stiffener 445 at least partially through the opening 443c of the cover 443. In some implementations, the thermally conductive probe 445b is configured to contact the bottom of the subject's foot (e.g., the subject's skin) when the system 400 is in use. In some implementations, the thermally conductive probe 445b is formed in the stiffener 445. To aid in its thermal conductivity, the thermally conductive probe 445b (and the stiffener 445) can be made from a conductive material (e.g., stainless steel (e.g., 430SS), etc.).Moreover, the stiffener 445 may include one or more slits 445c positioned adjacent to the thermally conductive probe 445b, which are configured to thermally isolate the thermally conductive probe 445b and / or a portion of the stiffener 445 from other portions of the stiffener 445 and aid in transmitting thermal energy from the bottom of the subject's foot toward the temperature sensor 404c. As shown, the stiffener 445 may include two slits 445c, which are oriented substantially perpendicular to one another, effectively thermally isolating the thermally conductive probe 445b. In some variations, the sensor hub 404 includes a thermally conductive probe (e.g., similar to the probe 445b) but does not include the stiffener 445 and / or such probe does not extend from the stiffener 445. In such variations, such a probe may still direct thermal energy toward the temperature sensor 404c.

[0105] Also shown in FIG. 14E is a circuit layer 447 that can be disposed under the cover 443 and the stiffener 445 and can be positioned at least partially within the sensor hub 404 and / or at least partially within the sensor strap 430. As discussed above, the circuit layer 447 can electrically connect the one or more emitters 404a and the one or more detectors 404b to various other electrical components of the sensor hub 404 (e.g., one or more processors of the sensor hub 404). In some implementations, the circuit layer 447 also electrically connects the temperature sensor 404c of the sensor dock 404 to various other electrical components of the sensor hub 404. The circuit layer 447 can be configured as a flexible circuit that can bend freely together with the sensor strap 430. In some implementations, the circuit layer 447 can have a length that is greater than the distance between where the circuit layer 447 electrically connects to the one or more emitters 404a and the one or more detectors 404b. For example, the circuit layer 447 can have one or more bends (e.g., can be serpentine). As shown in at least FIG. 14E, the circuit layer 447 can include a portion 453 configured to electrically connect to one or more emitters 404a, a portion 451 configured to electrically connect to one or more detectors 404b, and a portion 452 including at least one bend spanning between the portion 453 and the portion 451. The portion 453 can be positioned in a recess 455 of the sensor strap 430. At least a portion of the portion 452 can be positioned in a recess 454 of the sensor strap 430. The portion 451 can be positioned in the sensor hub 404. Thus, at least a portion of the circuit 447 can be positioned in the sensor strap 430, and at least a portion of the circuit 447 can be positioned in the sensor hub 404.Similar to the openings in the cover 443, the circuit layer 447 can include openings 447a and 447b that are configured to overlie the one or more detectors 404b and the one or more emitters 404a, respectively, and allow optical radiation to be received and / or emitted therethrough. As further shown, an adhesive layer 449 can be disposed between the stiffener 445 and the circuit layer 447 to bond each to one another, the adhesive layer including openings 449a similar to the openings 445a and 447a. Referring to FIG. 14F, in some implementations, the circuit layer 447 can be positioned between the thermally conductive probe 445b (and the stiffener 445) and the temperature sensor 404c.

[0106] FIG. 14G shows a view of the sensor hub 404 with a portion of its main body 420 and a portion of the sensor strap 430 removed from the view. In this view, temperature sensor 404d can be seen positioned away from thermal conductivity probe 445b and temperature sensor 404c (whose relative positions are best shown in the cross-sectional view of FIG. 14F). Temperature sensor 404d can be configured to measure the ambient temperature of the environment, while temperature sensor 404c can be configured to measure the body temperature of subject 1 via thermal conductivity probe 445b when system 400 is in use. In some implementations, temperature sensor 404d and temperature sensor 404c can be used in combination to determine at least the body temperature of subject 1 in a manner similar to or identical to the temperature sensor described and / or illustrated in U.S. Patent Application Publication No. 2006 / 0139994, entitled “Wearable Device for Noninvasive Body Temperature Measurement,” which is incorporated herein by reference in its entirety for all purposes. For example, the difference in temperature measured via temperature sensor 404c and via temperature sensor 404d can be used in determining the subject's body temperature. Additionally, system 400 can include and / or incorporate any of the methods for determining the subject's temperature described in U.S. Patent Application Publication No. 2006 / 0139993.

[0107] When thermal energy is transmitted to the temperature sensor 404c (e.g., via thermally conductive probe 445b), the temperature sensor 404c can determine the subject's body temperature and / or generate and transmit one or more signals in response to the thermal energy to one or more processors of the sensor hub 404. The temperature sensor 404c can be or include, for example, a thermocouple and / or a thermistor. The temperature sensor 404c can be a chip that is electrically and mechanically coupled to the circuit layer 447. The temperature sensor 404c can be configured to generate one or more signals in response to the detected thermal energy, determine the body temperature, and / or transmit such generated signal(s) and / or such determined body temperature to one or more processors of the sensor hub 404 continuously and / or intermittently. For example, the temperature sensor 404c can be configured to generate one or more signals in response to detected thermal energy, determine a body temperature, and / or transmit such generated signal or signals and / or such determined body temperature every 0.5 seconds, 1 second, 2 seconds, 3 seconds, 4 seconds, 5 seconds, 10 seconds, 30 seconds, 1 minute, 2 minutes, 3 minutes, 4 minutes, 5 minutes, or other intervals.

[0108] The temperature sensor 404d can be configured to generate one or more signals in response to the detected thermal energy, determine a temperature, and / or transmit such generated signal(s) and / or such determined temperature continuously and / or intermittently to one or more processors of the sensor hub 404. For example, the temperature sensor 404d can be configured to generate one or more signals in response to the detected thermal energy, determine a temperature, and / or transmit such generated signal(s) and / or such determined temperature every 0.5 seconds, every 1 second, every 2 seconds, every 3 seconds, every 4 seconds, every 5 seconds, every 10 seconds, every 30 seconds, every 1 minute, every 2 minutes, every 3 minutes, every 4 minutes, every 5 minutes, or other intervals. Such generated signal(s), determined temperature, and / or transmission of the generated signal(s) and / or determined temperature can be simultaneous or non-simultaneous with the generated signal(s), determined body temperature, and / or transmitted signal(s) and / or determined body temperature from the temperature sensor 404c.

[0109] Advantageously, the incorporation of both temperature sensors 404c, 404d may enable the sensor hub 404 to more accurately determine the subject's body temperature. For example, one or more processors of the sensor hub 404 may utilize the temperature data from temperature sensor 404d to adjust or "correct" the temperature data received from temperature sensor 404c to more accurately determine the subject's body temperature. For example, one or more processors of the sensor hub 404 may compare the temperature data received from both temperature sensors 404c, 404d and determine a corrected body temperature based on such comparison. The one or more processors may apply a weighting factor to one or both of the temperature data received from temperature sensors 404c, 404d and / or otherwise compare such received data to determine a corrected body temperature.

[0110] 15A-15E illustrate perspective views of a wearable device 402 of the system 400 of FIGS. 12A-12B according to some implementations of the present disclosure. The wearable device 402 can be configured to receive and support the foot 2, ankle 3, heel 4, and / or lower leg 5 of the subject 1. The wearable device 402 can be similar to the wearable devices 102, 302 described herein and can include any of such features, functionality, and / or components. For example, the wearable device 402 can be made of an elastic and / or flexible material similar or the same as the wearable devices 102, 302 described herein. The wearable device 402 can have a base 460 and a wall 462. The wall 462 can extend from the base 460. For example, the wall 462 can extend from a periphery of the base 460. In some implementations, the wall 462 can extend around a portion of the peripheral edge of the base 460. The base 460 and the wall 462 can form a main body portion 405 of the wearable device 402. In some implementations, the wearable device 402 can have a main body portion 405 including a base 460, an opening 471 in the base 460 that defines a cavity 472, and a wall portion 462 extending from the base 460. In some implementations, the main body portion 405 additionally includes a wearable device strap 466 (which may also be referred to herein as an “additional strap”) configured to connect to (e.g., releasably connect to) and extend from the wall portion 462. In some implementations, the system 400 includes only the strap 430 and does not include any other straps (e.g., does not include the wearable device strap 466).Moreover, in some implementations, the system 400 includes only the strap 430 and does not include any other straps (e.g., does not include the strap section 431), and such strap 430 is configured to be secured to a portion of the wearable device 402.

[0111] The base 460 (which may also be referred to herein as the "bottom portion") of the wearable device 402 may be configured to contact at least a portion of a bottom portion of the subject's foot 2 when the system 400 is in use. For example, the base 460 may be configured to contact the heel, arch, ball, and / or one or more toes of the subject's foot 2. An opening 471 in the base 460 may be configured to be positioned adjacent to a bottom portion of the subject's foot 2 when the system 400 is in use. For example, and as shown, the opening 471 may extend through the base 460 and be positioned such that it underlies a portion of the ball and / or arch of the subject's foot 2 when the wearable device is secured to the subject's foot 2. A cavity 472 defined by an opening 471 in the base 460 can extend below the base 460 and away from a bottom portion of the subject's foot 2 when the system 400 is in use. The cavity 472 can be configured to removably receive at least a portion of the sensor hub 404 and / or the sensor strap 430, for example, when the sensor hub 404 and the sensor strap 430 are connected to the wearable device 402. In other words, the cavity 472 can be configured to removably receive the sensor component 403 when the sensor component is connected to the wearable device 402. The wearable device 402 can include an opening 473, as shown, configured to aid in removing the sensor component 403 (e.g., the sensor hub 404 and the sensor strap 430) from the wearable device 402 when desired to do so.For example, the opening 473 can be disposed in the cavity 472 and can include a through opening through a bottom of the wearable device 402 that can be used by the subject to push the sensor component 403 to remove it from the wearable device 402. Such an opening 473 can also assist the subject in securing the sensor component 403 in the cavity 472. The wearable device 402 can also include an opening 479, as shown, that is configured to substantially align with the status indicator 425 of the sensor hub 404 when the sensor hub 404 is connected to the wearable device 402. The opening 479 can be disposed in the cavity 472 and can include a through opening through a bottom of the wearable device 402 that can allow the status of the sensor component 403 to be visible via the status indicator 425 when the system 400 is in use. In some implementations, the cavity 472 can include a protrusion 478 configured to interact with the electrical connector 424 of the sensor hub 404. For example, the protrusion 478 can be configured as a raised oval that fits into a corresponding oval recess in the electrical connector 424 of the sensor hub 404. Such a protrusion 478 can help secure the sensor hub 404 with the wearable device 402.

[0112] The walls 462 of the wearable device 402 may extend upwardly from the periphery of the base 460 and may include a side portion 462a (which may also be referred to herein as a “side wall portion”), a rear portion 462b (which may also be referred to herein as a “rear wall portion”), and a side portion 462c (which may also be referred to herein as a “side wall portion”) that are configured to wrap around and support a portion of the subject's foot 2 (e.g., a side of the subject's foot 2, the subject's ankle 3, the subject's heel 4, and / or the subject's lower leg 5, etc.). The walls 462 may be discontinuous such that they do not surround the entire periphery of the base 460, leaving space for the sensor strap 430 to extend from the opening 471 and recess 477 in the base 460. Moreover, the wall 462 can be discontinuous such that the toes of the subject's foot 2 are not encircled. The wall 462 can have a variable height as it extends upward from the base. For example, and as shown in FIGS. 15A-15E, the wall 462 can have a maximum height at the rear portion 462b and a reduced height at the side portions 462a and 462c to encircle and support the subject's heel 4. In some implementations, the main body portion 405 of the wearable device 402 can include a plurality of holes 464 for ventilation and / or to adjust the resiliency of the wearable device 402. For example, the wall 462 and / or the base 460 can have a plurality of holes 464 therethrough. Moreover, and in some implementations, the main body portion 405 of the wearable device 402 can include an opening 461 located in the rear portion 462b of the wall 462. The opening 461 can be configured to allow the wearable device 402 to fit over the heel 4 of the subject's foot 2.

[0113] 14A-14E , the wearable device 402 may also include one or more features for securing to the subject's foot 2. For example, and as shown, the main body portion 405 of the wearable device 402 may include the previously mentioned wearable device strap 466, which may connect to and extend outwardly from the wall portion 462, and a strap slot 463a (which may also be referred to herein as an "opening") configured to interact with the wearable device strap 466. The wearable device strap 466 may be configured to wrap over a portion of the subject's foot 2, ankle 3, and / or lower leg 5, with an end thereof placed through the strap slot 463a, and secure back on itself in a manner similar or identical to the wearable device strap 366. The wearable device strap 466 can connect to and extend from the side portion 462a of the wall 462 at a location adjacent to where the wearable device 402 would receive the subject's ankle 3 when secured to the subject 1. Additionally, the wearable device strap 466 can connect to and extend from the side portion 462a at an acute angle relative to the base 460 when viewed from the side of the wearable device 402. The strap slot 463a can include a slot through the side portion 462c of the wall 462 (e.g., the side of the wall 462 opposite where the wearable device strap 466 connects to and extends from), which is configured to receive the wearable device strap 466 therethrough. In some implementations, the wearable device strap 466 can be configured to releasably connect to the wall portion 462 via connectors 475 and 476 in a similar or identical manner to the wearable device strap 366 via connectors 375 and 376.

[0114] Also, the main body portion 405 of the wearable device 402 can include one or more features for releasably securing to the sensor strap 430 when the sensor hub 404 is connected to the wearable device 402 via the cavity 472. For example, and as shown, the base 460 can include a portion adjacent to an opening 471 that extends beyond where the bottom of the subject's foot 2 is received when the system 400 is worn, which includes a strap slot 463b (which can be the same as or similar to strap slot 463a, which can also be referred to herein as an "opening") that can interact with the sensor strap 430 in a manner similar or the same as how the strap slot 463a interacts with the wearable device strap 466 or in a manner similar or the same as how the strap slot 363b interacts with the sensor strap 330. To customize the fit of the system 400 to the subject's foot 2, the wearable device strap 466 and / or the sensor strap 430 can be wrapped over the subject's foot 2 and the ends of the straps can be placed through the strap slots 463a and 463b and secured back over the straps in a manner similar or identical to that described with respect to the system 300. In some implementations, the portion of the base 460 that includes the strap slots 463b can deform (e.g., it can bend and / or fold relative to the foot 2) when the sensor strap 430 is secured in the strap slots 463b (e.g., such as that shown in FIGS. 12A-12B). In some implementations, the strap slots 463b can be formed in a portion of the wall 462 (e.g., a portion of the wall 462c) rather than being included as an extension of the base 460.

[0115] In some implementations, and as shown in FIG. 15E, the wearable device 402 can include a main body portion 405 and a frame 480 (which can also be referred to herein as a “holder”). The main body portion 405 can include a first material, where the first material is elastic and flexible. For example, the main body portion 405 can include silicone rubber. The frame 480 can include a second material, where the second material is more rigid than the first material. For example, the frame 480 can include polycarbonate. The frame 480 can be configured to releasably receive at least a portion of the sensor component 403 when the sensor component 403 is connected to the wearable device 402. In other words, the frame 480 can be configured to releasably receive at least a portion of the sensor hub 404 and / or the sensor strap 430 to secure the sensor hub 404 and / or the sensor strap 430 to the wearable device 402. In this regard, the base 460 of the wearable device 402 can be configured to receive the frame 480 therein. For example, the cavity 472 can be configured to receive the frame 480. The frame 480 and the main body portion 405 can be integrally formed. For example, the main body portion 405 can be overmolded onto the frame 480 to create the wearable device 402. The frame 480 can have an opening 482 configured to releasably receive the sensor hub 404 when the sensor component 403 is connected to the wearable device 402. Moreover, the frame 480 can have a recess 487 configured to receive at least a portion of the sensor strap 430 when the sensor hub 404 is connected to the cavity 482.The recess 487 in the frame and the recess 477 in the main body portion 405 can allow the sensor strap 430 to extend away from the sensor hub 404 and the wearable device 402 such that the tops of the sensor hub 404 and / or the sensor strap 430 can form a substantially flush surface (e.g., be substantially coplanar) with the base 460 of the wearable device 402. Moreover, the opening 482 in the frame 480 and the cavity 472 in the main body portion 405 can be configured together to releasably connect to the sensory assembly 403 (e.g., the sensor hub 404). In some implementations, the frame 480 can include one or more features to aid in securing with the sensor component 403 (e.g., the sensor hub 404). For example, the frame 480 can include one or more protrusions or ridges extending inwardly toward the opening 482 that are configured to provide a frictional fit with at least a portion of the sensor component 403.

[0116] 16A-16D illustrate various perspective views of another implementation of a system 500 (which may also be referred to herein as a “wearable system,” “wearable sensor system,” or “wearable physiological sensor system”) secured to a subject's foot 2 and configured to measure at least one physiological parameter of the subject 1. The system 500 may have similar and / or identical features, aspects, functionality, and / or components as any of the systems described herein (e.g., systems 100, 300, 400, and / or any variations thereof). For example, the system 500 may have a wearable device 502 that is configured the same or similarly in some or many respects as the wearable device 402. As another example, the system 500 may include a sensor hub 504 and a sensor strap 530 (together, which may be referred to as a sensor component or sensor assembly 503), which are configured the same or similarly as the sensor hub 404 and the sensor strap 430 of the sensor component 403, respectively. The system 400 can be secured to the subject's foot 2, ankle 3, heel 4, and / or lower leg 5 in a manner similar or identical to how the system 400 can be secured to the subject 1. Moreover, the system 500 can include one or more emitters 504a (e.g., in an emitter package), one or more detectors 504b (e.g., in a detector package), and one or more temperature sensors 504c, which are similar or identical to the one or more emitters 404a, one or more detectors 404b, and one or more temperature sensors 404c of the system 400. The system 500 can also include an additional temperature sensor (in addition to the temperature sensor 504c), which can be similar or identical to the temperature sensor 404d, which can be located, for example, in the sensor hub 504.Such additional temperature sensors may be spaced apart from temperature sensor 504c and may function in conjunction with temperature sensor 504c in the same or similar manner as described above with respect to temperature sensors 404c and 404d.

[0117] The system 500 may include any of the features or components discussed with respect to FIG. 3 above. The system 500 may wirelessly communicate with one or more separate devices (which may be, for example, a patient monitor 10a, a cell phone 10b, a camera, a hub, or any other separate device described herein) via any of a variety of wireless communication protocols (such as, for example, any of those discussed herein with respect to the systems 100, 300, 400). Moreover, the system 500 may wirelessly transmit physiological data and / or physiological parameters of the subject to a separate device (such as, for example, a patient monitor 10a, a cell phone 10b, a camera, a hub, or any other separate device) as described herein with respect to the systems 100, 300, 400.

[0118] When secured to the subject's foot 2, the system 500 can operably position one or more emitters 504a and one or more detectors 504b adjacent a portion of the foot 2 (e.g., generally on either side of the subject's foot 2). For example, the system 500 can position one or more emitters 504a and one or more detectors 504b such that at least some of the optical radiation emitted by the one or more emitters 504a passes through tissue of the subject 1 before being detected by the one or more detectors 504b. As another example, the system 500 can position one or more detectors 504a adjacent a top and / or side of the subject's foot 2 and one or more emitters 504b adjacent a bottom of the subject's foot 2. The one or more emitters 504a and one or more detectors 504b do not need to be vertically aligned with one another and on either side of the subject's foot for the system 500 to operate. In some implementations, the positioning of the one or more emitters 504a and the one or more detectors 504b can be reversed. In some implementations, at least a portion of the sensor strap 530 and / or at least a portion of the sensor hub 504 operably positions the one or more emitters 504a and / or the one or more detectors 504b as described, for example, when the sensor hub 504 is secured to a portion of the wearable device 502. In some implementations, at least a portion of the sensor component 503 operably positions the one or more emitters 504a and / or the one or more detectors 504b as described. The system 500 can operably position a thermally conductive probe 545b that is configured to transmit thermal energy adjacent to the bottom of the subject's foot (e.g., such that it is in contact with the skin of the subject 1) and transmit thermal energy from the bottom of the subject's foot toward the temperature sensor 504c.

[0119] The system 500 may include a wearable device 502. The wearable device 502 may be configured to receive and / or secure an electronic device including one or more sensors for monitoring information regarding physiological parameters, movement, and / or location of the subject 1. For example, the wearable device may be configured to receive and / or secure a sensor component 503 (which may also be referred to herein as a "sensor assembly") or a portion thereof, as further described herein. Such a sensor component 503 may include a sensor hub 504 and a sensor strap 530. In some implementations, the system 500 may include a wearable device 502, a sensor hub 504, and a sensor strap 530. As shown in FIGS. 16A-B, the wearable device 502 and the sensor component 503 may be secured to each other and to the subject's foot. FIG. 16C illustrates the sensor component 503 detached from the wearable device 502. FIG. 16D illustrates an exploded view of the system 500. The wearable device 502 may have a wearable device strap 566 configured the same as or similar to the wearable device strap 466 of the wearable device 402, and as shown in FIG. 16D, the wearable device strap 566 may be removably connectable to the wearable device 502 (although in some implementations the wearable device strap 566 may be integrally formed with the wearable device 502). Also shown in FIG. 16D, the sensor component 503 may include a sensor hub 504 and a sensor strap 530, with at least a portion of the sensor strap (e.g., a fixed section) configured to be removably connectable thereto.

[0120] Although the figure illustrates an implementation in which the wearable device 502 and the sensor hub 504 and the sensor strap 530 are removably connectable to one another (or, in other words, the wearable device 502 and the sensor component 503 are removably connectable to one another), various ones of these components can be integrally formed with one another. For example, in some variations, the wearable device 502 and the sensor hub 504 are integrally formed and removably connectable to the sensor strap 530 or at least a portion thereof. As another example, in some variations, the sensor hub 504 and the sensor strap 530 are integrally formed and removably connectable to the wearable device 502. As another example, in some variations, the wearable device 502, the sensor hub 504, and the sensor strap 530 are integrally formed with one another (or, in other words, the wearable device 502 and the sensor component 503 are integrally formed with one another). Implementations of the system 500 in which the wearable device 502 is removably connectable to the sensor hub 504 and / or sensor strap 530 can advantageously allow wearable devices 502 of various sizes (e.g., small, medium, and large) and / or shapes to be utilized with the system 500, e.g., to accommodate various sizes and / or shapes of the subject's foot 2, ankle 3, heel 4, and / or lower leg 5. In this manner, the system 500 can be customized for the subject 1 by selecting an appropriately configured wearable device 502 while allowing all other aspects of the system 500 (e.g., the sensor hub 504 and sensor strap 530 or sensor component 503, etc.) to remain the same and / or be universal across subjects.16D , the sensor hub 504 and the sensor strap 530 form a sensor component 503 that can be removably connected to the wearable device 502. In some implementations, at least a portion (e.g., a fixed portion) of the sensor strap 530 and / or the wearable device strap 566 can come in a variety of sizes and / or lengths (e.g., small, medium, large) to advantageously provide a customized fit with any of the various sizes of wearable device 502.

[0121] 17A-17D illustrate various perspective views of the sensor component 503 and / or components / aspects thereof of the system 500. As shown, the sensor component 503 can include a sensor hub 504 and a sensor strap 530 (which can also be referred to herein as a "strap") that is connected to and extends outwardly from the sensor hub 504. The sensor hub 504 can include a generally rounded rectangular housing having a top, sides, and a bottom. In some implementations, the sensor hub 504 has a length and / or width that is greater than the height of the sensor hub 504. The sensor strap 530 can include one or more emitters 504a and / or one or more detectors 504b and can be configured to secure the system 500 to the subject's foot 2 (e.g., alone or in combination with a wearable device strap 566 of the wearable device 502) as described herein. The sensor strap 530 can be the same as or similar to the sensor strap 430 described herein, or can include any of the functionality and / or features of the sensor strap 430. In some implementations, the one or more detectors 504b are positioned within a portion of the sensor strap 530, and the one or more emitters 504a are positioned within a portion of the sensor hub 504. The one or more emitters 504a and the one or more detectors 504b can be in electrical communication with one or more processors of the sensor hub 504 via a circuit layer 547, which is disposed at least partially within the sensor strap 530 and at least partially within the sensor hub 504 (e.g., as shown in FIG. 17C ). The sensor strap 530 can have a top that sits substantially flush (e.g., substantially coplanar) with the sensor hub 504 (e.g., with a top of the sensor hub 504).Additionally, the sensor strap 530 can extend from the sensor hub 504 in a direction substantially perpendicular to the sensor hub 504. In some implementations, the sensor hub 504 can have a main body portion 520.

[0122] 17B, ​​the sensor hub 504 can include an electrical connector 524 configured to releasably connect to a charger (e.g., charger 499). The electrical connector 524 can be configured in a similar or identical manner as described elsewhere herein with respect to the electrical connector 424.

[0123] The strap 530 can include a sensor section 541 (which can be referred to as a "first section") and a fixed section 531 (which can be referred to as a "second section"), which can be similar or identical to the sensor section 441 and the fixed section 431 of the system 400 as described herein. For example, the sensor section 541 and the fixed section 531 can be releasably connectable to each other via connectors 538, 539, which can be similar or identical to the connectors 338, 438, 339, 439 as described elsewhere herein. In some implementations, at least a portion of the strap 530 is stretchable. For example, at least a portion of the sensor section 541 and / or at least a portion of the fixed section 531 can be configured to be stretchable. In some implementations, the sensor section 541 is more stretchable than the fixed section 531.

[0124] 17C-17D further illustrate perspective views of the sensor hub 504 and the sensor strap 530, which progressively show various aspects, components, and / or features that the sensor hub 504 and the sensor strap 530 may include. The sensor hub 504 and the sensor strap 530 may include any or all of the features and / or functionality of the sensor hub 406, the sensor dock 404, and the sensor strap 430 described herein. As shown in FIG. 17C, the sensor hub 540 and the sensor strap 530 may include a cover 543 (which may also be referred to as a "cover plate") configured to cover at least a portion of the electrical circuitry of the sensor hub 504 and the sensor strap 530 (e.g., circuit layer 547, etc.). The cover 543 may be similar or the same as the cover 443 described herein. The cover 543 can fit into recesses in the sensor hub 504 and the sensor strap 530 such that the cover 543 and surfaces of the sensor hub 504 and the sensor strap 530 adjacent the cover 543 form a substantially flush surface. The cover 543 can include openings 543b and 543a configured to overlie one or more detectors 504b and one or more emitters 504a, similar or identical to the openings 443b and 443a of the cover 443 described herein. In some implementations, such openings are covered by a transparent material (e.g., to prevent ingress of liquid therethrough). However, in alternative implementations, such openings are not covered.17C (in which an aspect of the sensor strap 541 has been removed from the view), in addition to the cover 543, the sensor hub 504 and / or strap 530 can include a stiffener 545 (which can be a plate made of metal, for example) configured to increase the stiffness of a portion of the sensor hub 504 and / or strap 530 positioned adjacent the bottom of the subject's foot when the sensor hub 504 is connected to the wearable device 502. The stiffener 545 can be disposed below the cover 543 and can include an opening 545a configured to allow optical radiation to pass therethrough (e.g., so as not to prevent optical radiation from being emitted by the one or more emitters 504a or optical radiation from being received by the one or more detectors 504b). As shown, the stiffener 545b can include the thermally conductive probe 545b described above, which is configured to transmit thermal energy from the bottom of the subject's foot toward the temperature sensor 504c. The thermally conductive probe 545b can be configured as a rounded protrusion that protrudes from the stiffener 545 at least partially through the opening 543c of the cover 543. In some implementations, the thermally conductive probe 545b is configured to contact the bottom of the subject's foot (e.g., the subject's skin) when the system 500 is in use. In some implementations, the thermally conductive probe 545b is formed in the stiffener 545. To aid in its thermal conductivity, the thermally conductive probe 545b (and the stiffener 545) can be made from a conductive material (e.g., stainless steel (e.g., 430SS), etc.). In some variations, the sensor hub 504 includes a thermally conductive probe (e.g., similar to probe 545b) but does not include a stiffener 545 and / or such probe does not extend from the stiffener 545.In such variations, such a probe would still be capable of directing thermal energy towards the temperature sensor 504c.

[0125] Also shown in FIG. 17C is a circuit layer 547 that can be disposed under the cover 543 and the stiffener 545 and can be positioned at least partially within the sensor hub 504 and / or at least partially within the sensor strap 530. As discussed above, the circuit layer 547 can electrically connect the one or more emitters 504a and the one or more detectors 504b to various other electrical components of the sensor hub 504 (e.g., one or more processors of the sensor hub 504). In some implementations, the circuit layer 547 also electrically connects the temperature sensor 504c of the sensor dock 504 to various other electrical components of the sensor hub 504. The circuit layer 547 can be configured as a flexible circuit that can bend freely together with the sensor strap 530. In some implementations, the circuit layer 547 can have a length that is greater than the distance between where the circuit layer 547 electrically connects to the one or more emitters 504a and the one or more detectors 504b. For example, the circuit layer 547 can include one or more bends (e.g., can be serpentine). As shown at least in FIG. 17C, the circuit layer 547 can include a portion 553 configured to electrically connect to one or more detectors 504a, a portion 551 configured to electrically connect to one or more emitters 504b, and a portion 552 including at least one bend spanning between the portion 553 and the portion 551. The portion 553 can be positioned in a recess 555 of the sensor strap 530. At least a portion of the portion 552 can be positioned in a recess 554 of the sensor strap 530. The portion 551 can be positioned in the sensor hub 504. Thus, at least a portion of the circuit layer 547 can be positioned in the sensor strap 530, and at least a portion of the circuit layer 547 can be positioned in the sensor hub 504.Similar to the openings in the cover 543, the circuit layer 547 can include openings 547b and 547a that are configured to overlie the one or more detectors 504b and the one or more emitters 504a, respectively, and allow optical radiation to be received and / or emitted therethrough. As further shown, an adhesive layer 549 can be disposed between the stiffener 545 and the circuit layer 547 to bond each to one another, the adhesive layer including openings 549a similar to the openings 545a and 547a. With reference to FIG. 17D, in some implementations, the circuit layer 547 can be positioned between the thermally conductive probe 545b (and the stiffener 545) and the temperature sensor 504c.

[0126] 18A-18D illustrate perspective views of a wearable device 502 of the system 500 of FIGS. 16A-16B according to some implementations of the present disclosure. The wearable device 502 can be configured to receive and support the foot 2, ankle 3, heel 4, and / or lower leg 5 of the subject 1. The wearable device 502 can be similar to and include any of the features, functionality, and / or components of the wearable devices 102, 302, 402 described herein. For example, the wearable device 502 can be made of an elastic and / or flexible material similar or the same as the wearable devices 102, 302, 402 described herein. The wearable device 502 can have a base 560 and a wall 562. The wall 562 can extend from the base 560. For example, the wall 562 can extend from a periphery of the base 560. In some implementations, the wall 562 can extend around a portion of the peripheral edge of the base 560. The base 560 and the wall 562 can form a main body portion 505 of the wearable device 502. In some implementations, the wearable device 502 can have a main body portion 505 including a base 560, an opening 571 in the base 560 that defines a cavity 572, and a wall portion 562 extending from the base 560. In some implementations, the main body portion 505 additionally includes a wearable device strap 566 (which may also be referred to herein as an “additional strap”) configured to connect to (e.g., releasably connect to) and extend from the wall portion 562. In some implementations, the system 500 includes only the strap 530 and does not include any other straps (e.g., does not include the wearable device strap 566).Moreover, in some implementations, the system 500 includes only the strap 530 and does not include any other straps (e.g., does not include the strap section 531), and such strap 530 is configured to be secured to a portion of the wearable device 502.

[0127] The base 560 (which may also be referred to herein as the "bottom portion") of the wearable device 502 may be configured to contact at least a portion of a bottom portion of the subject's foot 2 when the system 500 is in use. For example, the base 560 may be configured to contact the heel, arch, ball, and / or one or more toes of the subject's foot 2. An opening 571 in the base 560 may be configured to be positioned adjacent to a bottom portion of the subject's foot 2 when the system 500 is in use. For example, and as shown, the opening 571 may extend through the base 560 and be positioned such that it underlies a portion of the ball and / or arch of the subject's foot 2 when the wearable device is secured to the subject's foot 2. A cavity 572 defined by an opening 571 in the base 560 can extend below the base 560 and away from a bottom portion of the subject's foot 2 when the system 500 is in use. The cavity 572 can be configured to removably receive at least a portion of the sensor hub 504 and / or the sensor strap 530, for example, when the sensor hub 504 and the sensor strap 530 are connected to the wearable device 502. In other words, the cavity 572 can be configured to removably receive the sensor component 503 when the sensor component is connected to the wearable device 502. The wearable device 502 can include an opening 573, as shown, configured to aid in removing the sensor component 503 (e.g., the sensor hub 504 and the sensor strap 530) from the wearable device 502 when desired to do so.For example, the opening 573 can be disposed in the cavity 572 and can include a through opening through a bottom of the wearable device 502 that can be used by the subject to push the sensor component 503 to remove it from the wearable device 502. Such an opening 573 can also assist the subject in securing the sensor component 503 in the cavity 572. The wearable device 502 can also include an opening 579, as shown, that is configured to substantially align with a status indicator 525 of the sensor hub 504 when the sensor hub 504 is connected to the wearable device 502. The opening 579 can be disposed in the cavity 572 and can include a through opening through a bottom of the wearable device 502 that can allow a status of the sensor component 503 to be visible via the status indicator 525 when the system 500 is in use. In some implementations, the cavity 572 can include a protrusion 578 configured to interact with the electrical connector 524 of the sensor hub 504. For example, the protrusion 578 can be configured as a raised oval that fits into a corresponding oval recess in the electrical connector 524 of the sensor hub 504. Such a protrusion 578 can help secure the sensor hub 504 with the wearable device 502.

[0128] The walls 562 of the wearable device 502 may extend upwardly from the periphery of the base 560 and may include a side portion 562a (which may also be referred to herein as a “side wall portion”), a rear portion 562b (which may also be referred to herein as a “rear wall portion”), and a side portion 562c (which may also be referred to herein as a “side wall portion”) that are configured to wrap around and support a portion of the subject's foot 2 (e.g., a side of the subject's foot 2, the subject's ankle 3, the subject's heel 4, and / or the subject's lower leg 5, etc.). The walls 562 may be discontinuous such that they do not surround the entire periphery of the base 560, leaving space for the sensor strap 530 to extend from the opening 571 and recess 577 in the base 560. Moreover, the wall 562 can be discontinuous such that the toes of the subject's foot 2 are not encircled. The wall 562 can have a variable height as it extends upward from the base. For example, and as shown in FIGS. 18A-18D, the rear portion 562b of the wall 562 can have a height that can encircle and support the subject's heel 4, and can have a greater height at the side portions 562a and 562c. In some implementations, the main body portion 505 of the wearable device 502 can include a plurality of holes 564 for ventilation and / or for adjusting the resiliency of the wearable device 502. For example, the wall 562 and / or the base 560 can have a plurality of holes 564 therethrough. Moreover, and in some implementations, the main body portion 505 of the wearable device 502 can include an opening 561 located in the rear portion 562b of the wall 562. The opening 561 can be configured to allow the wearable device 502 to fit over the heel 4 of the subject's foot 2.

[0129] The wearable device 502 may also include one or more features for securing to the subject's foot 2. For example, the main body portion 505 of the wearable device 502 may include the previously mentioned wearable device strap 566, which may connect to and extend outwardly from the wall portion 562, and a strap slot 563a (which may also be referred to herein as an "opening") configured to interact with the wearable device strap 566. The wearable device strap 566 may be configured to wrap over a portion of the subject's foot 2, ankle 3, and / or lower leg 5, with its end placed through the strap slot 563a, and secure back on itself in a similar or identical manner to the wearable device strap 466. The wearable device strap 566 may connect to and extend from a side portion 562a of the wall portion 562 at a location adjacent to where the wearable device 502 would receive the subject's ankle 3 when secured to the subject 1. Additionally, the wearable device strap 566 can connect to and extend from the side portion 562a at an acute angle relative to the base 560 when viewed from the side of the wearable device 502. The strap slot 563a can include a slot through the side portion 562c of the wall 562 (e.g., the side of the wall 562 opposite where the wearable device strap 566 connects and extends therefrom) that is configured to receive the wearable device strap 566 therethrough. In some implementations, the wearable device strap 566 can be configured to releasably connect to the wall 562 via connectors 575 and 576 in a similar or identical manner to the wearable device strap 466 via connectors 475 and 476.

[0130] Also, the main body portion 505 of the wearable device 502 can include one or more features for releasably securing to the sensor strap 530 when the sensor hub 504 is connected to the wearable device 502 via the cavity 572. For example, and as shown, the base 560 can include a portion adjacent to an opening 571 that extends beyond where the bottom of the subject's foot 2 is received when the system 500 is worn, which includes a strap slot 563b (which can be the same as or similar to strap slot 563a, which can also be referred to herein as an "opening") that can interact with the sensor strap 530 in a manner similar or the same as how the strap slot 563a interacts with the wearable device strap 566, or in a manner similar or the same as how the strap slot 463b interacts with the sensor strap 430. To customize the fit of the system 500 to the subject's foot 2, the wearable device strap 566 and / or the sensor strap 530 can be wrapped over the subject's foot 2 and the ends of the straps can be placed through the strap slots 563a and 563b and secured back over the straps in a manner similar or identical to that described with respect to the system 400. In some implementations, the portion of the base 560 that includes the strap slot 563b can deform when the sensor strap 530 is secured in the strap slot 563b. In some implementations, the strap slot 563b can be formed in a portion of the wall 562 (e.g., a portion of the wall 562c) rather than being included as an extension of the base 560.

[0131] In some implementations, the wearable device 502 can include a main body portion 505 and a frame 580 (which can also be referred to herein as a "holder"), which can be the same or similar to the arrangement of the wearable device 402. The main body portion 505 can include a first material, which is elastic and flexible. For example, the main body portion 505 can include silicone rubber. The frame 580 can include a second material, which is stiffer than the first material. For example, the frame 580 can include polycarbonate. The frame 580 can be configured to releasably receive at least a portion of the sensor component 503 when the sensor component 503 is connected to the wearable device 502. In other words, the frame 580 can be configured to releasably receive at least a portion of the sensor hub 504 and / or the sensor strap 530 to secure the sensor hub 504 and / or the sensor strap 530 to the wearable device 502. In this regard, the base 560 of the wearable device 502 can be configured to receive the frame 580 therein. For example, the cavity 572 can be configured to receive the frame 580. The frame 580 and the main body portion 505 can be integrally formed. For example, the main body portion 505 can be overmolded onto the frame 580 to create the wearable device 502. The frame 580 can have an opening, the opening configured to releasably receive the sensor hub 504 when the sensor component 503 is connected to the wearable device 502. Moreover, the frame 580 can have a recess configured to receive at least a portion of the sensor strap 530 when the sensor hub 504 is connected to the cavity 582 .The recess in the frame and the recess 577 in the main body portion 505 can allow the sensor strap 530 to extend away from the sensor hub 504 and the wearable device 502 such that the top of the sensor hub 504 and / or the sensor strap 530 can form a substantially flush surface (e.g., be substantially coplanar) with the base 560 of the wearable device 502. Moreover, the opening in the frame 580 and the cavity 572 in the main body portion 505 together can be configured to releasably connect to the sensory assembly 503 (e.g., the sensor hub 504). In some implementations, the frame 580 can include one or more features to aid in securing with the sensor component 503 (e.g., the sensor hub 504). For example, the frame 580 can include one or more protrusions or ridges extending inwardly toward the opening configured to provide a frictional fit with at least a portion of the sensor component 503.

[0132] 19A-19B illustrate a monitoring system 1000 that may be utilized to monitor at least one physiological parameter, movement, and / or location of a subject (including any one or more of the physiological parameters described herein and / or others). The monitoring system 1000 may include a system 600, a camera 700, and a hub 800. The system 600 may be the same as or similar to the system 500 and may be secured to the subject's foot as shown in FIG. 19A. In this example, the subject may be an infant (which may also be referred to herein as a "baby" or a "child"), and the monitoring system 1000 may be adapted to monitor at least one physiological parameter, movement, and / or location of the infant. In some implementations, system 600 can be the same as or similar to and can include any of the functionality and / or features of any of the systems described herein (e.g., systems 100, 300, and / or 400, etc.). Camera 700 can be positioned to observe the subject. For example, camera 700 can be mounted on a wall near the infant's crib, on furniture near the infant, etc., where the camera can observe the infant. Hub 800 can be positioned within wireless communication range of system 600 and / or camera 700. For example, hub 700 can be positioned in the infant's room and / or in the room of the infant's parent and / or care provider. Various other optional aspects of system 600, camera 700, and hub 800 are described below with respect to FIGS. 20-22D.

[0133] As shown in FIG. 19B, the components of the monitoring system 1000 can be configured to wirelessly communicate with each other and / or with one or more separate electronic devices 900. For example, and as shown, the system 600 can be configured to wirelessly communicate with the hub 800 (or vice versa) and / or with the camera 700 (or vice versa). Continuing with this example, the camera 700 can be configured to wirelessly communicate with the hub 800 (or vice versa). Moreover, the hub 800 and / or the camera 700 can be configured to wirelessly communicate with the separate electronic device 900 (or vice versa). In some implementations, the hub 800 can receive all information provided wirelessly by the system 600 and / or the camera 700 and wirelessly forward such information to the separate electronic device 900. In some implementations, the camera 700 can receive all information provided wirelessly by the system 600 and wirelessly forward such information to the separate electronic device 900. The separate electronic device 900 can be any of the electronic devices described herein or others (e.g., a patient monitor, a mobile phone, a server, a sound bar, and / or a speaker, etc.). Communication between the system 600, the camera 700, and / or the hub 800 and the electronic device 900 can occur over a network. Such a configuration can advantageously provide access to the monitoring system 1000 by, for example, the infant's parents and / or care providers who may be located in a location different from where the system 1000 is located. Wireless communication can occur via any of the wireless communication protocols described herein. For example, the components of the monitoring system 1000 can be configured to communicate via Bluetooth and / or WiFi. As another example, the components of the monitoring system 1000 can be configured to pair with each other via NFC.Although FIG. 19A illustrates the hub 800 being in close proximity to the camera 700 and the system 600, in some situations the hub 800 may be in a different location than the camera 700 and / or the system 600 (e.g., a different room in a house).

[0134] 20 illustrates a schematic diagram of certain features that may be incorporated into system 600 and any other implementations of the systems described herein. Any of the features described with respect to system 600 can be incorporated into any of the other systems described herein (e.g., systems 100, 200, 300, 400, and / or 500, etc.). Similarly, system 600 can be embodied in any of the forms shown and / or described herein with respect to any of systems 100, 200, 300, 400, and / or 500. As an example, in some implementations, FIG. 20 can represent a schematic diagram of the sensor component 503 of system 500.

[0135] As shown, system 600 may include one or more emitters 620, one or more detectors 622, one or more temperature sensors 624, one or more processors 602, one or more storage devices 604, a communications module 606, a battery 608, an information element 610, one or more other sensors 626, one or more status indicators 612, a vibration motor 614, one or more accelerometers 616, and / or one or more gyroscopes 618. As non-limiting examples, the one or more emitters 620, the one or more detectors 622, the one or more temperature sensors 624, the one or more processors 602, the one or more storage devices 604, the communication module 606, the battery 608, the information element 610, the one or more other sensors 626, the one or more status indicators 612, the vibration motor 614, the one or more accelerometers 616, and the one or more gyroscopes 618 can be the same as or similar to or can include any one or more features and / or functionality of the one or more emitters 104a, the one or more detectors 104b, the one or more temperature sensors 104c, the one or more processors 106a, the one or more storage devices 106b, the communication module 106c, the battery 106d, the information element 106e, the one or more other sensors 106f (which can include one or more accelerometers and / or one or more gyroscopes), the one or more status indicators 106g, and the vibration motor 106h described herein.

[0136] The one or more accelerometers 616 and / or one or more gyroscopes 618 of the system 600 can be utilized to determine the movement, position, orientation, location, and / or other characteristics of a subject and / or a portion of the subject's body (e.g., the foot 2, the ankle 3, the heel 4, and / or the lower leg 5). For example, the one or more accelerometers 616 and / or one or more gyroscopes 618 of the system 600 can be utilized to determine whether the subject is lying down, on his / her back, lying on his / her side, on his / her stomach, on all fours, kneeling, partially standing, standing, asleep, awake, moving, and / or not moving. In some implementations, the one or more accelerometers 616 and / or one or more gyroscopes 618 of the system 600 can determine movement, position, orientation, location, and / or other characteristics of a subject and / or a portion of the subject's body in a manner similar to or identical to that described and / or illustrated in U.S. Patent Application Publication No. 2007 / 0139994, entitled “Patient Monitoring Device with Improved User Interface,” which is incorporated herein by reference in its entirety for all purposes.

[0137] 21A-21B illustrate various perspective views of an implementation of the camera 700 of the monitoring system 1000 of FIGS. 19A-19B. As stated, the camera 700 can be configured to monitor a subject when the monitoring system 1000 is in use. In this regard, the camera 700 can incorporate any one or more features and / or functionality of the charging station 200 described herein, as well as additional features and / or functionality. For example, the camera 700 can include a camera 702, a microphone 704, a communication module 706, a speaker 708, one or more humidity sensors 710, one or more status indicators 712, and / or one or more temperature sensors 714, as shown in FIG. 21C. The camera 702 can be configured for high-resolution capture of a subject in daytime, nighttime, high-light, low-light, and / or no-light environments. In some implementations, the camera 702 can be configured for night vision. The resolution of the camera 702 can be 720, 1080, 2k, 4k, or any resolution that provides the camera with the ability to monitor the subject and / or its environment. The microphone 704 can be configured to capture / monitor sounds from the subject and / or its environment. The communication module 706 can be configured the same as or similar to any of the communication modules described herein and can facilitate wireless communication of information collected and / or processed by the camera 700 (e.g., by one or more processors of the camera) to other components of the monitoring system 1000 and / or to a separate electronic device 900 connected thereto. The one or more humidity sensors 710 and one or more temperature sensors 714 can be configured to monitor the humidity and temperature of the environment in which the camera 700 is located. The camera 700 can be configured to enable communication between a parent / caregiver and an infant subject via the microphone 704 and speaker 708.Moreover, in some implementations, the camera 700 can be configured to sound an alarm in response to one or more physiological parameters, movements, and / or location of a subject being monitored by the monitoring system 1000. The camera 700 can be configured to be wall or ceiling mounted, furniture mounted (e.g., in a portion of a crib), or otherwise positionable such that it can monitor the subject and / or its environment.

[0138] 22A-22C illustrate various perspective views of the hub 800 of the monitoring system 1000 of FIGS. 19A-19B. The hub 800 can be similar to and incorporate any one or more features and / or functionality of the charging station 200 described herein. For example, and as shown in FIG. 22D, the hub 800 can include a communication module 824, a speaker 826, and a status indicator 830, the same as or similar to such components of the charging station 200. Additionally, the hub 800 can include a top surface or button 802, a body portion 806, an electrical connector 810, a bottom surface 804, an opening 808, an opening 809, and a reset button 814, the same as or similar to the top surface or button 202, a body portion 206, an electrical connector 210, a bottom surface 204, an opening 208, an opening 209, and a reset button 214 of the charging station 200. For example, the button 802 can be pressed to snooze the hub 800's alarm, to power the hub 800 on or off, or to otherwise interact with the hub 800. Instead of being configured to receive and charge the sensor hub, the hub 800 can differ from the charging station 200 in that the hub 800 can include a microphone 822, one or more humidity sensors 828, and / or one or more temperature sensors 832. The microphone 822, one or more humidity sensors 828, and one or more temperature sensors 832 can be configured to monitor the sound, humidity, and temperature of the environment in which the hub 800 is located. As shown in FIG. 19A, in some implementations, it may be desirable to position the hub 800 in an environment proximate to the subject. In some cases, when the subject is an infant / child, it may be advantageous to position the hub 800 in an environment proximate to the subject's parent and / or care provider. In some implementations, more than one hub 800 may be provided with the monitoring system 1000.The hub 800 can be configured to allow communication between a parent / caregiver and the infant subject via the microphone 822 and speaker 826. Additionally, in some implementations, the hub 800 can be configured to sound an alarm in response to one or more physiological parameters, movement, and / or location of the subject being monitored by the monitoring system 1000.

[0139] The monitoring system 1000 may be advantageously configured to monitor at least one physiological parameter, movement, and / or location of the subject 1 as described herein. For example, the monitoring system 1000 may be configured to monitor, measure, or otherwise determine vital signs of the subject 1, which may include the SpO2, heart / pulse rate, respiratory rate, temperature, oxygen saturation, and / or pulse rate of the subject 1. The monitoring system 1000 may also be configured to generate an alarm (e.g., communicate an alarm to a parent and / or care provider of the subject 1) based on any one or more of the physiological parameters, movement, and / or location of the subject 1.

[0140] Any of the components of the monitoring system 1000 can be configured to wirelessly pair with each other. For example, the components of the monitoring system 1000 can be configured to pair with each other via NFC and / or Bluetooth (e.g., low energy Bluetooth). Moreover, the components of the monitoring system 1000 can be configured to wirelessly pair with a separate electronic device (e.g., separate electronic device 900, etc.), which can include via NFC and / or Bluetooth (e.g., low energy Bluetooth). In some implementations, no button or button press may be required to pair the components of the monitoring system 1000 and / or the components of the monitoring system 1000 with one or more separate electronic devices. Moreover, and as described herein, any of the components of the monitoring system 1000 can be configured to communicate with each other or with the separate electronic device 900 via WiFi.

[0141] In some implementations, the monitoring system 1000 may include software configured to enable the subject, or when the subject is an infant, their parent or caregiver, to access and / or interact with the monitoring system 1000. For example, the monitoring system 1000 may include an application accessible via a separate electronic device 900 that the subject / their parent / their caregiver may use to access and / or interact with the monitoring system 1000 and / or any of its components. Such software may include one or more algorithms to enable the monitoring system 1000 to process data, physiological parameters, movements, and / or locations measured and / or determined by any one or more of the components of the monitoring system 1000.

[0142] When the subject is an infant as described herein, the monitoring system 1000 can be configured to enable the parent and / or caregiver of the infant to monitor various aspects of the infant's health, well-being, and / or safety. For example, the monitoring system 1000 can be configured to enable the parent / caregiver to set up a monitoring zone around the infant. Such a monitoring zone can be the infant's sleep or play environment, among others. The monitoring system 1000 can be configured to monitor such monitoring zones and communicate alarms to the parent / care provider when necessary. For example, the monitoring system 1000 can be configured to detect: infant safety within such monitoring zones (e.g., hands or feet outside the crib, infant about to fall, or attempting to climb on or off various structures); whether any foreign objects (e.g., pillows, toys, pets, household items, cell phones) are within such monitoring zones, have moved into such monitoring zones, and / or have entered such monitoring zones; infant positioning within such monitoring zones (e.g., lying down, lying on one's back, lying on one's side, lying on one's stomach, on all fours, kneeling, partially standing, standing, face up, face down, respiratory inhibition, non-restrained respiratory inhibition, and / or the positioning of the infant relative to aspects of the infant's environment (e.g., in the center of the crib or near the side); and / or the infant's activity within such monitoring zone (e.g., sleeping, awake, moving / walking / crawling, not moving, crying, beginning to cry, breathing, and / or not breathing). Components of the monitoring system 1000 may advantageously work in combination for detection of the various aspects described above.For example, the camera 700 and the system 600 can work in combination to provide positioning information about the infant subject (e.g., the accelerometer 616 and / or gyroscope 618 of the system 600 can work in combination with the camera 700 to determine the positioning of the infant subject and / or portions thereof). As another example, the camera 700 and the system 600 can work in combination to provide any one or more of the infant subject's vital signs (e.g., the camera 700 can be configured to monitor and determine the subject's vital signs, such as, for example, heart rate, respiratory rate, and the like). In some implementations, the monitoring zone can include anything and everything within the field of view of the camera 700 and / or within range of the microphones of the camera 700 and / or hub 800. In some implementations, the monitoring zone can be set to include the infant subject's crib, bassinet, play area, bath area, or other areas. In some implementations, the monitoring system 1000 can be configured to provide universal and continuous access to the subject's video, audio, and vitals. The monitoring system 1000 can be configured to provide customizable alerts and / or alarms based on aspects of the infant subject and / or its environment. In some implementations, the monitoring system 1000 can provide detailed data history, access to knowledge and / or video libraries, social media connectivity, and / or live vital tracking with connection to doctors / hospitals / care providers.

[0143] In some implementations, the monitoring system 1000 includes only the system 600 and the camera 700. In some implementations, the monitoring system 1000 includes only the system 600, the camera 700, and one or more separate electronic devices 900. In some implementations, the monitoring system 1000 includes the system 600, the camera 700, the hub 800, and one or more separate electronic devices 900. In some implementations of the monitoring system 1000 including at least the camera 700 and the hub 800, the camera 700 and the hub 800 are configured to be installed in different rooms from each other.

[0144] Although examples and specific orientations and configurations of various embodiments of the systems described in this disclosure (e.g., systems 100, 300, 400, 500, and 600) have been provided, alternative orientations and configurations for such embodiments should be considered included as part of this disclosure. For example, in some implementations, wearable device strap 166, 366, 466, 566, and / or 666 can be omitted. In such implementations, sensor strap 130, 330, 430, 530, and / or 630 can be the only component of sensor dock 104 and / or 304 and / or sensor assembly 103, 303, 403, 503, and / or 603 (and / or systems 100, 300, 400, 500, and / or 600) that secures wearable device 102, 302, 402, 502, and / or 602 to subject's foot 2, respectively. As another example, in some implementations, the wearable device straps 166, 366, 466, 566, and / or 666 can be combined and / or coupled with the sensor straps 130, 330, 430, 530, and / or 630 (e.g., to form one larger strap that can be configured to secure the wearable device 102, 302, 402, 502, and / or 602 to the subject's foot 2). Any of the straps described herein can be configured to wrap around at least a portion of the subject's foot 2, which can include the bottom, top, one or more sides, and / or, in some cases, the entirety of the subject's foot 2. Additionally, although specific fastening methods for the straps described herein have been provided, other methods can be used, including via magnets and / or adhesives. Moreover, in some implementations, the wearable devices 102, 302, 402, 502, and / or 602 described herein can include fabric or non-elastic materials.In such implementations, the wearable device 102, 302, 402, 502, and / or 602 and any straps thereof can be configured to wrap around a portion of the subject's foot to secure the system 100, 300, 400, 500, and / or 600 to the subject. In some implementations, the wearable device 102, 302, 402, 502, and / or 602 described herein can include portions that are elastic, flexible, and / or rigid. In some implementations, the wearable device 102, 302, 402, 502, and / or 602 described herein can include portions made from silicone rubber and portions made from cloth.

[0145] Also, other orientations and configurations of the sensor straps 130, 330, 430, 530, and / or 630 should be considered as part of this disclosure. For example, although sensor straps 130, 330, 430, 530, and 630 may be described herein as including one or more emitters (e.g., such as emitters 104a, 304a, 404a, and 504a), one or more detectors (e.g., such as detectors 104b, 304b, 404b, and 504b), and / or a temperature sensor (e.g., such as temperature sensors 104c, 304c, 404c, and / or 404d, 505c, and / or additional temperature sensors), more than each of such emitters, detectors, and / or temperature sensors may be included in sensor straps 130, 330, 430, 530, 630 and / or sensor hubs 404, 504, 604. In some implementations, the sensor strap 130, 330, and / or 430 can include an array of emitters, an array of detectors, and / or an array of temperature sensors. Such an array can be configured to extend along the length of the sensor strap 130, 330, and / or 430 such that multiple emitters can be positioned proximate to one another, multiple detectors can be positioned proximate to one another, and / or multiple temperature sensors can be positioned proximate to one another. Advantageously, such an array can facilitate measurement of at least one physiological parameter of the subject, for example, by providing the system with options as to which emitters, detectors, and / or temperature sensors to utilize for measurement (e.g., the system can cycle through such sensors and use the one that provides the best signal for the physiological parameter determination).Additionally, although the emitters 104a, 304a, 404a, 504a, and 604a in some implementations have been described herein as being adjacent to tissue on the top of the subject's foot 2, and the detectors 104b, 304b, 404b, 504b, and 604b in some implementations have been described herein as being adjacent to tissue on the bottom of the subject's foot 2 when the systems 100, 300, 400, 500, and 600 are respectively fixed to the subject's foot 2, their locations may be swapped (e.g., the detectors may be configured to be adjacent to tissue on the top of the subject's foot 2 and the emitters may be configured to be adjacent to tissue on the bottom of the subject's foot 2).

[0146] Also, alternative configurations of holders 170 and 370 should be considered included as part of this disclosure. For example, while holders 170 and 370 have been shown herein as having enclosed perimeters to form cavities 172 and 372 for receiving sensor dock 104 / sensor hub 106 and sensor dock 304 / sensor hub 306, respectively, in some implementations holders 170 and / or 370 can have open sides to facilitate releasable connection / disconnection of sensor hub 106 and / or 306 with sensor dock 104 and / or 304.

[0147] Any of the systems described herein (e.g., systems 100, 300, 400, 500, and 600, etc.) and / or components thereof can be configured to be waterproof, water-resistant, splash-proof, shock-resistant, dust-proof, and / or dust-resistant. Although the systems have been described as having rechargeable batteries, the batteries can be non-rechargeable or single-use. In some implementations, the system's battery (e.g., battery 106d and / or such battery 165 implementations) can be rechargeable but non-removable from the device. In such cases, the system can include a charging port configured to accept a power cable for charging and / or an electrical connector configured to accept a charger. Further, in such cases, the system can be used by the subject while charging (e.g., the system can be in an operational mode while charging). In some variations, any sensor hub of the systems described herein (e.g., sensor hubs 106 and 306, etc.) may be permanently connected to any sensor dock of the systems described herein (e.g., sensor docks 104 and 304, etc.) In such variations, the combined sensor hub / sensor dock may have a charging port or electrical connector for charging.

[0148] In some implementations, any or all of the components of a system as described herein can be configured to be reusable (which may also be referred to herein as "durable"). For example, with reference to system 100, wearable device 102, sensor dock 104, and sensor hub 106 can all be configured to be reusable (e.g., for days, weeks, months, or longer). In such cases, all components can be sanitized between uses and / or subjects. In some implementations, all components of a system as described herein can be configured to be reusable, except for wearable devices as described herein (e.g., wearable devices 102, 302, 402, 502, and / or 602, etc.). In some cases, all components of a system as described herein may be configured to be reusable between subjects (e.g., subjects do not share use of wearable devices), except for wearable devices as described herein (e.g., wearable devices 102, 302, 402, 502, and / or 602, etc.). In some implementations, a sensor hub as described herein (e.g., sensor hubs 106 and 306, etc.) outlasts all other components of the system and may be reused, if desired, between subjects. In some implementations, one or more components of a system as described herein, and any portion thereof, may be configured as single use (which may be referred to herein as "disposable").In such implementations, the sensor hub and sensor dock as described herein can be integrated into, be part of, and / or otherwise combined with a wearable device as described herein to provide a single and fully integrated device that can be secured to the subject's foot 2. Moreover, in such implementations, the system can include a single-use battery and / or a non-rechargeable battery (e.g., a zinc-air battery). In some cases, all components of the system as described herein can be configured to be single-use, except for the sensor hub (e.g., sensor hub 106, 306, 404, 504, 604).

[0149] Additional Embodiments 1. A system for measuring at least one physiological parameter of a subject, comprising: A wearable device configured to be secured to a foot of a subject; a sensor component, removably securable to the wearable device and including one or more sensors for measuring the at least one physiological parameter of the subject, the sensor component further including a sensor strap configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device, thereby securing the wearable device and the sensor component to the subject's foot; Including, the system. 2. the sensor strap includes a first portion of a sensor component, the first portion configured to be wrapped around the portion of the subject's foot and secured to a first portion of a wearable device; 2. The system of embodiment 1, wherein the second portion of the sensor component is configured to be removably fixed to the second portion of the wearable device. 3. The system of embodiment 2, wherein the wearable device defines a first volume configured to receive a subject's foot and a second volume configured to removably receive the second portion of the sensor component. 4. Wearable devices are a base configured to contact at least a portion of a bottom of a subject's foot, the second volume of the wearable device being formed by a cavity in the base; a wall extending outwardly from the base and configured to encircle at least a portion of the heel and one or more sides of the subject's foot; 4. The system of embodiment 3, comprising: 5. the wearable device further includes a frame disposed within the cavity, the frame configured to removably secure the second portion of the sensor component; the base and the wall form a unitary structure made from a first material; 5. The system of embodiment 4, wherein the frame is made from a second material that is stiffer than the first material. 6. A system as described in embodiment 4 or 5, wherein the first portion of the wearable device is positioned on a portion of the wall. 7. The system of embodiment 6, wherein the first portion of the wearable device includes an opening in the portion of the wall, and the sensor strap is configured to be inserted through the opening. 8. A system as described in any of embodiments 4 to 7, wherein the first volume is defined by the base and the wall at a location above the cavity of the base. 9. A system as described in any of embodiments 4 to 8, wherein the wall portion extends around a portion of the peripheral edge of the base. 10. The system of embodiment 9, wherein the wall portion extends around less than the entire peripheral edge of the base. 11. The system of any of embodiments 4 to 10, wherein the wall does not extend around the entire cavity. 12. The sensor component comprises: a sensor hub including one or more processors, the sensor hub being configured to be removably secured to the second portion of the wearable device, the sensor strap being connected to the sensor hub and extending outwardly from the sensor hub; one or more emitters configured to emit optical radiation into tissue of the subject's foot, the one or more emitters positioned in the sensor hub; one or more detectors positioned in the sensor strap, the one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through tissue and output at least one signal in response to the detected optical radiation, and one or more processors of the sensor hub configured to receive the at least one signal output by the one or more detectors and determine the at least one physiological parameter of the subject; 12. The system of any one of embodiments 2 to 11, comprising: 13. The system of embodiment 12, wherein the system is configured such that when the sensor hub is secured to the second portion of the wearable device and the sensor strap is secured to the first portion of the wearable device, the one or more detectors are positioned adjacent to a top or side portion of the subject's foot and the one or more emitters are positioned adjacent to a bottom portion of the subject's foot. 14. A system as described in embodiment 12 or 13, wherein the sensor hub and the sensor strap form a unitary structure. 15. The sensor strap is a first section connected to the sensor hub and extending outwardly from the sensor hub, the one or more detectors being positioned within the first section; a second section releasably connectable to the first section, the second section configured to be secured to the first portion of a wearable device; 15. The system of any one of embodiments 12 to 14, comprising: 16. The system of embodiment 15, wherein the first section and the second section have different lengths and / or the first section and the second section comprise different materials. 17. The system of embodiment 15 or 16, wherein the first section is more stretchable than the second section. 18. A system described in any of embodiments 12 to 17, wherein the sensor strap is configured to be stretched to allow adjustment of the position of the one or more detectors relative to the subject's foot. 19. The sensor hub is a housing including an opening configured to be positioned adjacent to the skin of the subject's foot when the sensor hub is secured to the second portion of the wearable device; a thermally conductive probe positioned at least partially within the opening; a temperature sensor positioned within the housing; Including, A system described in any of embodiments 12 to 18, wherein the thermal conductivity probe is configured to at least partially transmit thermal energy from the skin toward the temperature sensor. 20. The system of embodiment 19, wherein the thermal conductivity probe extends through the opening and is configured to contact the skin of the subject's foot. 21. The sensor strap is configured to be wrapped around a portion of the subject's foot and secured to a first portion of a wearable device; A system as described in any of embodiments 1 to 20, wherein the system further includes an additional strap that is removably securable to a second portion of the wearable device and is configured to (i) be wrapped around another portion of the subject's foot or a portion of the subject's ankle or leg, and (ii) be secured to a third portion of the wearable device. 22. The sensor strap is configured to be wrapped around a portion of the subject's foot and secured to a first portion of the wearable device; A system as described in any of embodiments 1 to 21, further comprising an additional strap having a first end and a second end, the first end being connected to a second portion of the wearable device and the second end being configured to (i) be wrapped around another portion of the subject's foot or a portion of the subject's ankle or leg, and (ii) be secured to a third portion of the wearable device. 23. A system for measuring at least one physiological parameter of a subject, comprising: a wearable device configured to be secured to a foot of a subject, the wearable device including a cavity; a sensor hub configured to be removably secured within a cavity of a wearable device, the sensor hub including one or more processors; a sensor strap connected to the sensor hub and extending outwardly from the sensor hub and configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device; one or more emitters configured to emit optical radiation into tissue of the subject's foot, the one or more emitters disposed in one of the sensor hub and the sensor strap; one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through tissue and to output at least one signal in response to the detected optical radiation, the one or more detectors disposed in the other of the sensor hub and the sensor strap; Including, The system, wherein the one or more processors of the sensor hub are configured to receive at least one signal output by the one or more detectors and determine at least one physiological parameter of the subject. 24. The system of embodiment 23, wherein the wearable device is configured such that the cavity is positioned adjacent to a bottom portion of the subject's foot when the wearable device is secured to the subject's foot. 25. The system the one or more detectors are configured to be positioned adjacent an upper portion of the subject's foot when the system is in use; and 25. The system of embodiment 23 or 24, wherein the one or more emitters are configured to be positioned adjacent to a plantar portion of a subject's foot when the system is in use. 26. When the sensor hub is secured within the cavity and the sensor strap is secured to a portion of the wearable device, the one or more detectors are disposed within the sensor strap such that they face toward the sensor hub; A system described in any of embodiments 23 to 25, wherein the one or more emitters are positioned in the sensor hub so as to face toward the sensor strap. 27. A system described in any of embodiments 23 to 26, wherein the sensor hub and the sensor strap form a unitary structure. 28. The sensor strap is a first section connected to the sensor hub and extending outwardly from the sensor hub, the one or more detectors being positioned within the first section; a second section releasably connectable to the first section, the second section configured to be secured to a portion of the wearable device; 28. The system of any one of embodiments 23 to 27, comprising: 29. The system of embodiment 28, wherein the first section and the second section have different lengths. 30. The system of embodiment 28 or 29, wherein the first section is more stretchable than the second section. 31. Wearable devices are A main body portion, a base configured to contact at least a portion of a bottom of a subject's foot, the base including the cavity; a wall extending outwardly from the base and configured to encircle at least a portion of the heel and one or more sides of the subject's foot; a main body portion including a frame positioned within the cavity, the frame configured to be removably secured to a sensor hub; 31. The system of any one of embodiments 23 to 30, comprising: 32. The system of embodiment 31, wherein the main body is made from a first material and the frame is made from a second material that is stiffer than the first material. 33. The base includes a base surface configured to contact the at least a portion of the bottom of the subject's foot; the cavity has a first depth below the base surface; The system of embodiment 31 or 32, wherein the wearable device further includes a recess positioned along an outer edge of the base adjacent to the cavity, the recess having a second depth below the base surface, the second depth being smaller than the first depth and substantially equal to a thickness of a sensor strap, the recess being configured to receive a portion of the sensor strap when the sensor hub is secured within the cavity, such that the sensor hub and the portion of the sensor strap form a surface substantially flush with the base surface. 34. The sensor strap is configured to be wrapped around a portion of the subject's foot and secured to a portion of a wearable device, the portion of the wearable device being a first portion of the wearable device; A system as described in any of embodiments 23 to 33, further comprising an additional strap separate from the sensor strap and configured to (i) be wrapped around another part of the subject's foot or a part of the subject's ankle or leg, and (ii) be secured to a second part of the wearable device. 35. The sensor hub is a housing including an opening configured to be positioned adjacent to the skin of the subject's foot when the sensor hub is secured within the cavity of the wearable device; a thermally conductive probe positioned at least partially within the opening; a temperature sensor positioned within the housing; Including, A system described in any of embodiments 23 to 34, wherein the thermal conductivity probe is configured to at least partially transmit thermal energy from the skin toward the temperature sensor. 36. The system of embodiment 35, wherein the thermally conductive probe extends through the opening and is configured to contact the skin when the system is in use. 37. The one or more detectors are disposed in a sensor strap and the one or more emitters are disposed in a sensor hub; the wearable device further includes a flexible circuit extending through a portion of the sensor hub and a portion of the sensor strap and electrically connecting the one or more detectors to the one or more processors or to another circuit to which the one or more processors are connected; the portion of the sensor strap is configured to be stretched from a first condition to a second condition, the portion of the sensor strap having a greater length when in the second condition than when in the first condition; the one or more detectors are disposed at a first location within the portion of the sensor strap that is spaced a first distance from a sensor hub; A system as described in any of embodiments 23 to 36, wherein a length of a portion of the flexible circuit positioned within the portion of the sensor strap is greater than the first distance, allowing the flexible circuit to accommodate the stretching of the portion of the sensor strap from a first state to a second state while maintaining a connection between one or more detectors and one or more processors or the other circuit to which the one or more processors are connected. 38. The one or more detectors are disposed in a sensor strap and the one or more emitters are disposed in a sensor hub; A system described in any of embodiments 23 to 37, wherein the sensor strap is configured to be stretched to allow adjustment of the position of the one or more detectors relative to the subject's foot. 39. A system for measuring at least one physiological parameter of a subject, comprising: A wearable device configured to be secured to a foot of a subject; A sensor hub configured to be removably secured to the wearable device; Including, The sensor hub is a housing including an opening configured to be positioned adjacent a portion of a subject's foot; a thermally conductive probe positioned at least partially within the opening; a temperature sensor positioned within the housing; Including, The thermal conductivity probe is configured to at least partially transmit thermal energy from the portion of the subject's foot toward the temperature sensor. 40. The system of embodiment 39, wherein the temperature sensor is positioned within the housing such that the temperature sensor does not contact the subject's skin when the system is in use. 41. The system of embodiment 39 or 40, wherein the system further includes a sensor strap that connects to a sensor hub and extends outwardly from the sensor hub, the sensor strap and the sensor hub forming a unitary structure, and the sensor strap is configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device. 42. The system one or more emitters disposed in the sensor hub and configured to emit optical radiation into tissue of the subject's foot; one or more detectors disposed in the sensor strap and configured to detect at least a portion of the emitted optical radiation after passing through tissue and output at least one signal in response to the detected optical radiation; one or more processors disposed within the sensor hub and configured to receive at least one signal output by the one or more detectors and determine at least one physiological parameter of the subject; 42. The system of embodiment 41, further comprising: 43. The temperature sensor is a first temperature sensor of a sensor hub; The sensor hub is a second temperature sensor spaced apart from the first temperature sensor; one or more processors configured to receive temperature data from each of the first temperature sensor and the second temperature sensor and determine one or more body temperature values ​​of the subject based on the received temperature data; 43. The system of any of embodiments 39 to 42, further comprising: 44. The sensor hub is a metal plate positioned within the housing, the thermal conductivity probe extending transversely to a plane of the metal plate; a circuit layer positioned adjacent to the metal plate, the temperature sensor being attached to the circuit layer, the circuit layer being positioned between the temperature sensor and the metal plate; 44. The system of any one of embodiments 39 to 43, further comprising: 45. A system described in any of embodiments 39 to 44, wherein the thermally conductive probe includes a rounded protrusion. 46. ​​A system described in any of embodiments 39 to 45, wherein the thermal conductivity probe protrudes through the opening and is configured to contact the skin of the subject's foot when the system is in use. 47. A wearable device configured to be secured to a subject's foot, the wearable device defining a first volume configured to receive at least a portion of the subject's foot and a second volume configured to removably receive and secure an electronic device including one or more sensors for monitoring information regarding at least one of a physiological parameter, location, and movement of the subject, the wearable device comprising a material configured to allow at least a portion of the wearable device to elastically deform. 48. A wearable device as described in embodiment 47, wherein the wearable device is configured such that when at least a portion of the subject's foot is received by the first volume, the second volume is positioned adjacent to the bottom of the subject's foot. 49. A wearable device as described in embodiment 47 or 48, wherein the second volume is smaller than the first volume. 50. Wearable devices are a base configured to contact at least a portion of a bottom of a subject's foot, the second volume of the wearable device being formed by a cavity in the base; and a wall extending outwardly from a base and configured to encircle at least a portion of a heel and one or more sides of a subject's foot, wherein the first volume of the wearable device is defined by the base and the wall at a location above the cavity in the base; A wearable device as described in any of embodiments 47 to 49, comprising: 51. The wall includes a first side wall portion configured to be positioned adjacent a first side of the subject's foot, a second side wall portion configured to be positioned adjacent a second side of the subject's foot, and a rear wall portion configured to be positioned adjacent a heel of the subject's foot; A wearable device as described in embodiment 50, wherein the first side wall portion, the second side wall portion, and the rear wall portion form a unitary structure. 52. The wearable device further includes a frame disposed within the cavity, the frame configured to removably secure the electronic device; the base and the wall form a unitary structure made from a first material; A wearable device as described in embodiment 50 or 51, wherein the frame is made of a second material that is stiffer than the first material. 53. A wearable device as described in any of embodiments 50 to 52, wherein the wall portion extends around a portion of the peripheral edge of the base. 54. A wearable device as described in embodiment 53, wherein the wall portion extends around less than the entire peripheral edge of the base. 55. A wearable device as described in any of embodiments 50 to 54, wherein the wall portion does not extend around the entire cavity. 56. The wearable device further includes a strap, the strap comprising: a first end integrally connected to or removably connectable to a first portion of the wall; a second end opposite the first end, the second end configured to be wrapped around a portion of the subject's foot and further configured to secure the strap to a second portion of the wall; A wearable device as described in any of embodiments 50 to 55, having the following. 57. The wearable device of embodiment 56, wherein the second portion of the wall includes an opening, and the second end of the strap is configured to be inserted through the opening and secured to a portion of the strap. 58. A system comprising a wearable device described in any of embodiments 47 to 57 and an electronic device. 59. The system of embodiment 58, wherein the electronic device includes a sensor hub. 60. The system of embodiment 58 or 59, wherein the wearable device includes a first opening configured to allow an electronic device to be inserted into the cavity and a second opening configured to assist in removing the electronic device from the wearable device, the first opening having a different size than the second opening. 61. A kit comprising: a first wearable device defining a first volume configured to receive at least a portion of the subject's foot and a second volume configured to removably receive and secure an electronic device including one or more sensors for monitoring information regarding at least one of a physiological parameter, a location, and a movement of the subject; a second wearable device defining a first volume configured to receive at least a portion of the subject's foot and a second volume configured to removably receive and secure the electronic device; Including, the first volumes of the first wearable device and the second wearable device are different; A kit, wherein the second volumes of the first wearable device and the second wearable device are substantially equal. 62. A kit as described in embodiment 61, wherein each of the second volumes of the first wearable device and the second wearable device is configured to be positioned adjacent to the bottom of the subject's foot when at least a portion of the subject's foot is received by the respective first volume. 63. The second volume of the first wearable device is smaller than the first volume of the first boot; 62. The kit of embodiment 61, wherein the second volume of the second wearable device is smaller than the first volume of the second boot. 64. A system comprising a first wearable device and a second wearable device as described in embodiment 61 or 62, and further comprising an electronic device. 65. The system of embodiment 64, wherein the electronic device includes a sensor hub. 66. Each of the first wearable device and the second wearable device a base configured to contact at least a portion of a bottom of a subject's foot, the second volume of the wearable device being formed by a cavity in the base; and a wall extending outwardly from the base and configured to encircle at least a portion of the heel and one or more sides of the subject's foot; The system of embodiment 64 or 65, comprising: 67. Each of the first wearable device and the second wearable device further includes a frame disposed within the cavity, the frame configured to removably secure to the sensor hub; the base and the wall form a unitary structure made from a first material; 67. The system of embodiment 66, wherein the frame is made of a second material that is stiffer than the first material. 68. A system as described in embodiment 66 or 67, wherein the first volume of the first wearable device and the second wearable device is defined by the base and the wall portion at a location above the cavity of the base. 69. The system of any of embodiments 66 to 68, wherein the wall portion extends around a portion of the peripheral edge of the base. 70. The system of embodiment 69, wherein the wall portion extends around less than the entire peripheral edge of the base. 71. The system of any of embodiments 66 to 70, wherein the wall does not extend around the entire cavity. 72. A system configured to be secured to a subject's foot and ankle and to measure at least one physiological parameter of the subject, comprising: The wearable device includes: a main body portion comprising a resilient material and configured to receive and support a subject's foot and ankle; an opening in the main body portion configured to be positioned adjacent a bottom portion of a subject's foot when the wearable device is in use; a holder connected to the main body portion and extending outwardly from the main body portion adjacent the opening, the holder configured to extend away from a bottom portion of the subject's foot when the wearable device is in use; Including, The system also: a sensor dock configured to removably connect to a holder of the wearable device; The sensor dock is a main body portion configured to be received within a holder for a wearable device; a sensor strap connected to and extending outwardly from the main body portion of the sensor dock, configured to be positioned at least partially within and extend outwardly from an opening in the main body portion of the wearable device when the main body portion of the sensor dock is connected to the holder of the wearable device, and further configured to be wrapped around an upper portion of the subject's foot to secure the wearable device to the subject's foot when in use; one or more emitters operably positioned within a first portion of the sensor strap and configured to be positioned adjacent an upper portion of the subject's foot when the sensor strap is wrapped around the upper portion of the subject's foot, the one or more emitters configured to emit optical radiation into tissue of the subject's foot when in use; one or more detectors operably positioned in a second portion of the sensor strap spaced apart from the first portion of the sensor strap and configured to be positioned adjacent a bottom portion of the subject's foot when the wearable device is in use, the one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through the tissue and to output at least one signal in response to the detected optical radiation; Including, The system also includes a sensor hub configured to removably connect to the sensor dock, the sensor hub including one or more processors and a battery; When the sensor hub is connected to the sensor dock, the sensor dock is configured to receive power from the battery of the sensor hub to enable operation of the one or more emitters and the one or more detectors; The system, wherein the one or more processors of the sensor hub are configured to receive and process the at least one signal output by the one or more detectors of the sensor dock assembly to determine at least one physiological parameter of the subject. 73. The system of embodiment 72, wherein the at least one physiological parameter includes blood oxygen saturation. 74. A system as described in embodiment 72 or 73, wherein the sensor dock further includes a temperature sensor usable to determine the subject's body temperature. 75. The system of embodiment 74, wherein the temperature sensor is operably positioned within the second portion of the sensor strap and configured to be positioned adjacent to a bottom portion of the subject's foot when the wearable device is in use. 76. A system described in any of embodiments 72 to 75, wherein the sensor strap is configured to wrap around an upper portion of the subject's foot and be secured to a portion of the main body of the wearable device. 77. A system described in any of embodiments 72 to 76, wherein a first portion of the sensor strap is configured to be positioned opposite a second portion of the sensor strap when the sensor strap is wrapped around the upper portion of the subject's foot. 78. The system of any of embodiments 72 to 77, further comprising an emitter package including one or more emitters, and a detector package including one or more detectors. 79. The system of embodiment 78, wherein the emitter package and the detector package are generally aligned with each other when the sensor strap is wrapped around the upper portion of the subject's foot. 80. The system of any of embodiments 72 to 79, wherein the holder comprises an elastic material. 81. A system described in any of embodiments 72 to 80, wherein the holder includes a cavity configured to removably receive the main body portion and sensor hub of the sensor dock when the sensor hub is connected to the sensor dock. 82. A system described in any of embodiments 72 to 81, wherein the sensor strap is the only component of the sensor dock that secures the wearable device to the subject's foot. 83. A system described in any of embodiments 72 to 82, wherein the system further includes a wearable device strap configured to secure the main body of the wearable device to the subject's lower leg and / or ankle. 84. The system of embodiment 83, wherein the main body of the wearable device includes a connector for removably connecting to a wearable device strap. 85. The system of embodiment 83, wherein the wearable device strap is integrally formed with the main body of the wearable device. 86. A system described in any of embodiments 72 to 85, wherein the main body of the wearable device includes a base, the base being configured to contact a bottom portion of the subject's foot when the wearable device is in use, and the base including the opening. 87. The system of embodiment 86, wherein the base is configured to contact one or more of the heel of the subject's foot, the arch of the subject's foot, the ball of the subject's foot, and one or more toes of the subject's foot. 88. The system of embodiment 86, wherein a portion of the base adjacent the opening is generally flush with the second portion of the sensor strap when the sensor dock is connected to the holder of the wearable device. 89. The system of embodiment 86, wherein the holder extends below the base. 90. A system described in any of embodiments 72 to 89, wherein the sensor strap includes a sensor section including a first portion and a second portion, and a fixation section configured to fix the sensor strap to the wearable device. 91. The system of embodiment 90, wherein the stationary section and the sensor section are configured to be removably connected to each other. 92. A system described in any of embodiments 72 to 91, wherein the main body of the wearable device includes a wall configured to surround the heel of the subject's foot. 93. The system of embodiment 92, wherein the wall portion is further configured to at least partially surround one or more sides of the subject's foot. 94. A system described in any of embodiments 72 to 93, wherein the main body of the wearable device includes a slot for receiving a portion of the sensor strap. 95. A system as described in any of embodiments 72 to 94, wherein the sensor strap includes one or more emitters, one or more detectors, and a circuit layer in electrical communication with the electrical connector of the sensor dock, and the electrical connector of the sensor dock engages with the electrical connector of the sensor hub when the sensor hub is connected to the sensor dock. 96. The system of embodiment 95, wherein the circuit layer is flexible. 97. A system as described in any of embodiments 72 to 96, wherein the main body of the sensor dock includes a base and two arms extending from the base and separated from one another by a gap sized to receive the sensor hub, and the arms are configured to removably connect to the sides of the sensor hub. 98. The system of embodiment 97, wherein the arm of the sensor dock includes one or more retaining features, the one or more retaining features configured to engage with one or more corresponding retaining features on the side of the sensor hub. 99. One or more retaining features of the arms of the dock include one or more protrusions extending from an inwardly facing surface of said arms; A system as described in embodiment 98, wherein one or more corresponding retaining features on a side of the sensor hub include one or more recesses configured to receive the one or more protrusions. 100. The system of any of embodiments 72 to 99, further comprising an optically transmissive material configured to be positioned between the one or more emitters and tissue of the subject's foot when the wearable device is secured to the subject's foot. 101. The system of embodiment 100, wherein the optically transmissive material is configured to diffuse optical radiation emitted from the one or more emitters. 102. A system described in any of embodiments 72 to 101, wherein the system further includes an optically transparent material, the optically transparent material being configured to be positioned between the one or more detectors and tissue of the subject's foot when the wearable device is secured to the subject's foot. 103. The system of embodiment 102, wherein the optically transmissive material comprises a lens. 104. A system described in any of embodiments 72 to 103, wherein the sensor dock does not include a battery. 105. A system described in any of embodiments 72 to 104, wherein the sensor dock does not include a processor. 106. A system described in any of embodiments 72 to 105, wherein the sensor dock is configured to transition from a non-operational mode when the sensor hub is disconnected from the sensor dock to an operational mode when the sensor hub is connected to the sensor dock. 107. The system of embodiment 106, wherein in an operational mode, the system is configured to determine at least one physiological parameter of the subject. 108. A system described in any of embodiments 72 to 107, wherein the sensor dock includes an RFID tag configured to communicate with the RFID reader of the sensor hub. 109. A system as described in any of embodiments 72 to 108, wherein the sensor hub includes a communication module configured to wirelessly communicate with a separate device. 110. A system described in any of embodiments 72 to 109, wherein the sensor hub includes a vibration motor in electrical communication with the one or more processors, the one or more processors configured to instruct the vibration motor to cause the sensor hub to vibrate. 111. The one or more processors: comparing the determined at least one physiological parameter to one or more thresholds; The system of embodiment 110, wherein the system is configured to instruct the vibration motor to cause the sensor hub to vibrate based on the comparison of the determined at least one physiological parameter with the one or more thresholds. 112. A system described in any of embodiments 72 to 111, wherein the sensor hub includes one or more status indicators in electrical communication with the one or more processors, and the one or more processors are configured to instruct the one or more status indicators to cause the sensor hub to emit sound and / or optical radiation. 113. The one or more processors: comparing the determined at least one physiological parameter to one or more thresholds; The system of embodiment 112, wherein the system is configured to instruct the one or more status indicators to cause the sensor hub to emit sound and / or optical radiation based on the comparison of the determined at least one physiological parameter with the one or more thresholds. 114. A system configured to be secured to a foot of a subject and to measure at least one physiological parameter of the subject, comprising: A wearable device, A main body part; a holder connected to and extending outwardly from the main body portion; A wearable device comprising: A sensor component configured to removably connect to a holder of a wearable device, comprising: a sensor strap configured to wrap around an upper portion of the subject's foot to secure the wearable device to the subject's foot; one or more emitters operably positioned within a first portion of the strap and configured to be positioned adjacent one of a top or bottom portion of the subject's foot when the strap is wrapped around the top portion and when the wearable device is secured to the subject's foot, the one or more emitters configured to emit optical radiation into tissue of the subject's foot when in use; one or more detectors operably positioned within the second portion of the strap and configured to be positioned adjacent the other of the top or bottom portion of the subject's foot when the wearable device is secured to the subject's foot, configured to detect at least a portion of the emitted optical radiation after passing through the tissue and to output at least one signal in response to the detected optical radiation; one or more processors configured to receive and process the at least one signal output by the one or more detectors to determine the at least one physiological parameter of the subject; and a sensor component including: 115. The system of embodiment 114, wherein the main body of the wearable device comprises an elastic material. 116. The system of embodiment 114 or 115, wherein the system further includes a wearable device strap configured to secure the main body of the wearable device to the subject's lower leg and / or ankle. 117. A system described in any of embodiments 114 to 116, wherein the sensor component includes a sensor dock and a sensor hub, the sensor hub including one or more processors and a battery and configured to removably connect to the sensor dock. 118. A system described in any of embodiments 114 to 117, wherein a first portion of the sensor strap is configured to be positioned opposite a second portion of the sensor strap when the sensor strap is wrapped around the upper portion of the subject's foot. 119. A system described in any of embodiments 114 to 118, wherein the sensor strap is configured to wrap around an upper portion of the subject's foot and be secured to a portion of the main body of the wearable device. 120. A system described in any of embodiments 114 to 119, wherein the main body of the wearable device includes a wall configured to surround the heel of the subject's foot. 121. The system of embodiment 120, wherein the wall portion is further configured to at least partially surround one or more sides of the subject's foot. 122. A system described in any of embodiments 114 to 121, wherein the main body of the wearable device includes a base, the base is configured to contact a bottom portion of the subject's foot when the wearable device is in use, and the base includes an opening, the opening is configured to be positioned adjacent to the bottom portion of the subject's foot when the wearable device is in use. 123. The system of embodiment 122, wherein the sensor strap is configured to be positioned at least partially within the opening and extend outwardly from the opening when the sensor component is connected to the holder of the wearable device. 124. A system described in any of embodiments 114 to 123, wherein the holder comprises an elastic material and a cavity, the cavity being configured to removably receive the sensor component. 125. A system configured to be secured to a foot of a subject and to measure at least one physiological parameter of the subject, comprising: The wearable device portion includes: a main body portion configured to receive a foot of a subject; a strap configured to wrap around an upper portion of the subject's foot and secure to a portion of the main body; one or more emitters operably positioned within a portion of the strap and configured to be positioned adjacent an upper portion of the subject's foot when the wearable device portion is secured to the subject's foot, and configured to emit optical radiation into tissue of the subject's foot when in use; one or more detectors operably positioned within a portion of the wearable device portion and configured to be positioned adjacent a bottom portion of the subject's foot when the wearable device portion is secured to the subject's foot, the one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through the tissue and to output at least one signal in response to the detected optical radiation; Including, The system also includes a sensor hub including one or more processors and a battery, the sensor hub comprising: to provide power to enable operation of one or more emitters and one or more detectors; and receiving and processing the at least one signal output by the one or more detectors to determine the at least one physiological parameter of the subject; The system is configured to removably connect to a wearable device portion. 126. The system of embodiment 125, wherein the main body portion of the wearable device portion comprises an elastic material. 127. The system of embodiment 125 or 126, wherein the system further includes a wearable device strap configured to secure the main body portion of the wearable device portion to the subject's lower leg and / or ankle. 128. A system described in any of embodiments 125 to 127, wherein the main body portion of the wearable device portion includes a wall portion configured to surround the heel of the subject's foot. 129. The system of embodiment 128, wherein the wall portion is further configured to at least partially surround one or more sides of the subject's foot. 130. A system described in any of embodiments 125 to 129, wherein the wearable device portion further includes a temperature sensor usable to determine the subject's body temperature. 131. A system described in any of embodiments 125 to 130, wherein the wearable device portion does not include a battery. 132. A system described in any of embodiments 125 to 131, wherein the wearable device portion does not include a processor. 133. A system described in any of embodiments 125 to 132, wherein the wearable device portion is configured to transition from a non-operational mode when the sensor hub is disconnected from the wearable device portion to an operational mode when the sensor hub is connected to the wearable device portion. 134. A system as described in embodiment 133, wherein in an operational mode, the system is configured to determine at least one physiological parameter of the subject. 135. A system as described in any of embodiments 125 to 134, wherein the wearable device portion includes a wearable device and a sensor dock configured to be removably connected to each other, the wearable device includes the main body portion and a holder, the sensor dock includes the strap and a main body portion connected to the strap, and the main body portion of the sensor dock is configured to be received within at least a portion of the holder of the wearable device. 136. A system for monitoring a physiological status of a subject, comprising: a wearable device configured to be secured to a subject's foot, the wearable device including a base and a wall, the base configured to extend along and contact a bottom portion of the subject's foot, and the wall extending upwardly from the base and configured to extend along at least a portion of the subject's lower leg; at least one emitter configured to be positioned adjacent one of a top portion or a bottom portion of the subject's foot when the wearable device is in use, and configured to emit optical radiation into tissue of the subject's foot when in use; at least one detector configured to be positioned adjacent the other of the top portion or bottom portion of the subject's foot when the wearable device is in use, and configured to detect at least a portion of the emitted optical radiation after passing through the tissue, and to output at least one signal in response to the detected optical radiation; one or more processors configured to receive and process the at least one signal output by the at least one detector to determine at least one physiological parameter of the subject; Including, the system. 137. A sensor component for a system, the system being configured to be secured to a foot of a subject and to measure at least one physiological parameter of the subject, the sensor component comprising: a strap configured to wrap around at least a portion of the subject's foot to secure the system to the subject's foot; one or more emitters operably positioned within a first portion of the strap and configured to be positioned adjacent one of a top or bottom portion of the subject's foot when the strap is wrapped around said portion and when the system is secured to the subject's foot, the one or more emitters configured to emit optical radiation into tissue of the subject's foot when in use; one or more detectors operably positioned within the second portion of the strap and configured to be positioned adjacent the other of the top or bottom portion of the subject's foot when the system is secured to the subject's foot, and configured to detect at least a portion of the emitted optical radiation after passing through the tissue and output at least one signal in response to the detected optical radiation; one or more processors configured to receive and process the at least one signal output by the one or more detectors to determine the at least one physiological parameter of the subject; , a sensor component. 138. A system configured to be fixed to a foot of a subject and to measure at least one physiological parameter of the subject, comprising: a wearable device including a base and an opening therethrough; a sensor strap including one or more emitters and one or more detectors, the sensor strap configured to fit within and extend from the opening; Including, a portion of the sensor strap that fits within the opening configured to form a flush surface with the base to receive a bottom portion of the subject's foot; A portion of the sensor strap extending from the opening is configured to wrap around the subject's foot and secure the wearable device to the subject's foot. 139. A system configured to be secured to a foot of a subject and to measure at least one physiological parameter of the subject, comprising: a wearable device configured to receive a foot of a subject, the wearable device including a cavity; a sensor hub including one or more processors and one or more detectors, the sensor hub being removably securable within the cavity of the wearable device; a sensor strap connected to a sensor hub and extending outwardly from the sensor hub, configured to be wrapped around a portion of a subject's foot and secured to a portion of the wearable device, and including one or more emitters configured to emit optical radiation into tissue of the subject's foot when in use; Including, the one or more detectors of the sensor hub are configured to detect at least a portion of the emitted optical radiation after passing through the tissue and output at least one signal in response to the detected optical radiation; The one or more processors of the sensor hub are configured to receive and process the at least one signal output by the one or more detectors to determine the at least one physiological parameter of the subject. 140. The system of embodiment 139, wherein the cavity is positioned adjacent to a bottom portion of the subject's foot when the system is in use. 141. A system described in embodiment 139 or 140, wherein the one or more emitters are positioned adjacent to an upper or side portion of the subject's foot when the system is in use. 142. A system described in any of embodiments 139 to 141, wherein the one or more detectors are positioned adjacent to a plantar portion of the subject's foot when the system is in use. 143. A system described in any of embodiments 139 to 142, wherein the sensor hub and the sensor strap are integrally formed. 144. The sensor strap is a sensor section including the one or more emitters; a fastening section configured to be fastened to the portion of the wearable device; A system described in any of embodiments 139 to 143, comprising: 145. A system as described in any of embodiments 139 to 144, wherein the sensor hub further includes a communication module configured to wirelessly communicate with a separate device. 146. A system described in any of embodiments 139 to 145, wherein the sensor hub further includes a communication module configured to wirelessly communicate with a separate device. 147. We...

Claims

1. 1. A system for measuring at least one physiological parameter of a subject, comprising: A wearable device configured to be secured to the subject's foot; a sensor component, the sensor component being removably securable to the wearable device and comprising one or more sensors for measuring the at least one physiological parameter of the subject, the sensor component further comprising a sensor strap configured to be wrapped around a portion of the subject's foot and secured to a portion of the wearable device, thereby securing the wearable device and the sensor component to the subject's foot; Including, the system.

2. the sensor strap includes a first portion of the sensor component, the first portion configured to be wrapped around the portion of the subject's foot and secured to a first portion of the wearable device; The system of claim 1 , wherein the second portion of the sensor component is configured to be removably secured to a second portion of the wearable device.

3. 3. The system of claim 2, wherein the wearable device defines a first volume configured to receive a foot of the subject and a second volume configured to removably receive the second portion of the sensor component.

4. The wearable device comprises: a base configured to contact at least a portion of a bottom of the subject's foot, the second volume of the wearable device being defined by a cavity in the base; and a wall extending outwardly from the base and configured to encircle at least a portion of a heel and one or more sides of the subject's foot; The system of claim 3 , comprising:

5. The wearable device further includes a frame disposed within the cavity, the frame configured to removably secure the second portion of the sensor component; the base and the wall form a unitary structure made from a first material; The system of claim 4 , wherein the frame is made from a second material that is stiffer than the first material.

6. The system of claim 4 or 5, wherein the first portion of the wearable device is disposed on a portion of the wall.

7. 7. The system of claim 6, wherein the first portion of the wearable device includes an opening in the portion of the wall, and the sensor strap is configured to be inserted through the opening.

8. The system of claim 4 , wherein the first volume is defined by the base and the wall at a location above the cavity in the base.

9. The system of claim 4 , wherein the wall extends around a portion of a peripheral edge of the base.

10. The system of claim 9 , wherein the wall extends around less than the entire peripheral edge of the base.

11. The system of claim 4 , wherein the wall does not extend around the entire cavity.

12. The sensor component comprises: a sensor hub including one or more processors, the sensor hub configured to be removably secured to the second portion of the wearable device, the sensor strap connected to the sensor hub and extending outwardly from the sensor hub; one or more emitters configured to emit optical radiation into tissue of the subject's foot, the one or more emitters positioned in the sensor hub; one or more detectors configured to detect at least a portion of the emitted optical radiation after passing through the tissue and to output at least one signal in response to the detected optical radiation, the one or more detectors being positioned in the sensor strap, the one or more processors of the sensor hub being configured to receive the at least one signal output by the one or more detectors and determine the at least one physiological parameter of the subject; The system of claim 2 , comprising:

13. 13. The system of claim 12, wherein the system is configured such that when the sensor hub is secured to the second portion of the wearable device and the sensor strap is secured to the first portion of the wearable device, the one or more detectors are positioned adjacent to a top or side portion of the subject's foot and the one or more emitters are positioned adjacent to a bottom portion of the subject's foot.

14. The system of claim 12 or 13, wherein the sensor hub and the sensor strap form a unitary structure.

15. The sensor strap comprises: a first section connected to and extending outwardly from the sensor hub, the one or more detectors being positioned within the first section; a second section releasably connectable to the first section, the second section configured to be secured to the first portion of the wearable device; The system of any one of claims 12 to 14, comprising:

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