Electrospinning nozzle equipped with gas ejection means

Abstract

One embodiment of the present invention relates to an electrospinning nozzle including a gas ejection means for forming a plurality of air holes in a circumferential region radially spaced a predetermined distance from a hollow needle through which a spinning solution is ejected, and ejecting air through the air holes to generate an air flow that moves straight toward a charged filament jet of the spinning solution, thereby preventing the air flow from directly contacting the spinning solution, thereby stably forming a filament jet at a tip of the spinning nozzle and adjusting the filament jet so as not to exceed a specific range.

Description

[Technical Field]

[0001] This application claims priority based on Korean Patent Application No. 10-2022-0134761, filed on October 19, 2022, the entire contents of which are incorporated herein by reference in their entirety in the specification and drawings thereof.

[0002] The present invention relates to an electrospinning device, and more particularly to an electrospinning nozzle equipped with a gas ejection means for forming an air flowing layer that moves straight against a charged filament formed by a spinning solution discharged from the spinning nozzle. [Background technology]

[0003] The electrospinning process is a process of producing nanofibers in an electric field environment by applying a high DC voltage of several thousand to several tens of thousands of volts to a solution and connecting a collector to ground or negative voltage.

[0004] The charged droplets of the spinning solution discharged from the spinning nozzle are formed into a cone shape from the tip of the nozzle, and the cone-shaped protrusion extends longitudinally toward the collecting plate to form a charged filament. The cone-shaped part of the droplet is called a Taylor cone, and the longitudinally extending charged filament is called a jet.

[0005] The jet stretched from the protruding part of the Taylor cone undergoes a whipping mode, where the jet oscillates rapidly from any point above the critical high voltage, and the solvent evaporates, producing nanofibers with a very small diameter.

[0006] When a spinning solution with high surface tension is used, the surface tension of the droplets is greater than the electrical force, making it difficult to convert the Taylor cone into a jet of charged filaments. In other words, if some of the charged droplets are not converted into charged filaments, some of the spinning solution discharged from the spinning nozzle may be deposited on the collecting plate in the form of small droplets. This adversely affects the production of webs made of nanofibers at the nanometer level.

[0007] To solve these problems, spinning is performed by reducing the discharge rate from the spinning nozzle. However, due to the high voltage between the spinning nozzle and the accumulating plate, the Taylor cone at the tip of the spinning nozzle becomes unstable, or the jet of charged filaments cannot maintain a consistent direction and cannot be uniformly accumulated on the accumulating plate. Furthermore, reducing the discharge rate of the spinning solution reduces the productivity of the electrospinning process.

[0008] In an attempt to solve these technical problems, various technical innovations have been made.

[0009] Patent Document 1 proposes an electrospinning nozzle module for drug coating, which is characterized in that electricity for drug injection is supplied to a nozzle unit and nitrogen gas is ejected through an ejection hole arranged concentrically around the nozzle unit to eject the drug. However, the nitrogen gas ejected from the ejection hole arranged around the nozzle unit of Patent Document 1 tends to vaporize the solvent of the drug ejected from the nozzle, solidifying the drug and potentially clogging the nozzle outlet during injection.

[0010] Patent Document 2 discloses an electrospinning system including an electrospinning nozzle pack, which is characterized in that a plurality of gas injection nozzles communicating with a space for accommodating a gas such as air are provided on a main body, and a corresponding solution injection nozzle penetrates the center of each gas injection nozzle. However, because the gas injection nozzles in Patent Document 2 are arranged in a manner that surrounds the solution injection nozzle, the solution discharged from the solution injection nozzle is likely to be vaporized and solidified by the gas injected from the gas injection nozzle, which may cause clogging of the inlet of the solution injection nozzle. [Prior art documents] [Patent documents]

[0011] [Patent Document 1] Korean Patent No. 10-1440448 [Patent Document 2] Korean Patent No. 10-1478184 Summary of the Invention [Problem to be solved by the invention]

[0012] In the above-mentioned conventional techniques, particularly Patent Documents 1 and 2, gas is injected adjacent to the spinning nozzle that discharges the solution, so the spinning solution is directly affected by the airflow, and the spinning solution and the injected gas mix or come into contact with each other during spinning.

[0013] Therefore, the present invention aims to provide a method for forming a plurality of air holes in a circumferential region radially spaced a predetermined distance from a hollow needle through which the spinning solution is discharged, and to generate a straight air flow toward the charged filament jet of the spinning solution by ejecting air through the air holes, thereby preventing the air flow from directly contacting the spinning solution, thereby stably forming a filament jet at the tip of the spinning nozzle and controlling the filament jet so that it does not exceed a specific range. In particular, the straight air flow is focused on the charged filaments in the whipping mode section.

[0014] Other objects and advantages of the present invention can be understood from the following description and become more apparent from the embodiments of the present invention, and can be realized by the means and combinations thereof as set forth in the claims. [Means for solving the problem]

[0015] In order to solve the above-mentioned technical problems, an electrospinning nozzle according to a first aspect of the present invention includes an inner nozzle body into which a first fluid, i.e., a spinning solution, is injected; an inner needle connected to the inner nozzle body and having a hollow tubular inner needle as an outlet for the first fluid; an outer nozzle body into which a second fluid, i.e., air, is injected; a gas ejection means coupled to an end of the outer nozzle body and generating a flow of the second fluid, i.e., air, that moves straight toward charged filaments formed by the spinning solution ejected from the inner needle; and a high voltage application means connected to the inner nozzle body, wherein the gas ejection means includes a central hole through which the inner needle passes and a plurality of gas ejections arranged radially around the central hole at a predetermined distance apart.

[0016] The electrospinning nozzle according to the second aspect of the present invention is characterized in that, in the first aspect, the gas outlet comprises a plurality of air holes, at least two of which are arranged at regular intervals in a plurality of circumferential regions consisting of at least one row of circular lines around the central hole, and which discharge the second fluid, i.e., air, to the outside.

[0017] The electrospinning nozzle according to a third aspect of the present invention is the second aspect, wherein the gas outlet includes a first gas outlet having at least two air holes arranged in a first circumferential region that is a first circular line spaced apart from the central hole by a radius r1 and surrounding the central hole, and a second gas outlet having at least two air holes arranged in a second circumferential region that is a second circular line spaced apart from the central hole by a radius r2 and surrounding the central hole, wherein the radius r2 of the second circumferential region is greater than the radius r1 of the first circumferential region.

[0018] The electrospinning nozzle according to the fourth aspect of the present invention is characterized in that in the third aspect, a plurality of n-th circumferential regions (where n is a natural number greater than or equal to 3) are further arranged outside the second circumferential region surrounding the second circumferential region, and at least two air holes are arranged in the n-th circumferential region.

[0019] The electrospinning nozzle according to the fifth aspect of the present invention is the electrospinning nozzle of the third or fourth aspect, characterized in that six air holes are arranged at an angle of 60° to each other in the first circumferential region, the second circumferential region, and the nth circumferential region.

[0020] The electrospinning nozzle according to a sixth aspect of the present invention is the electrospinning nozzle of the fifth aspect, characterized in that the radius r1 is 3 mm to 5 mm, and the radius r2 is 4 mm to 10 mm.

[0021] The electrospinning nozzle according to a seventh aspect of the present invention is the fifth aspect, wherein the gas ejection means is an air cap including: a side fastening part coupled to an end extending from the outer nozzle body; and a cover part having the central hole and a plurality of gas outlets arranged surrounding the central hole, wherein the side fastening part and the cover part form a retention space for the second fluid, i.e., air.

[0022] An electrospinning nozzle according to an eighth aspect of the present invention includes an inner nozzle part body into which a first fluid is injected, an inner needle part connected to the inner nozzle part body and having a hollow tubular inner needle as an outlet for the first fluid, an outer nozzle part body into which a second fluid is injected, an outer needle part connected to the outer nozzle part body and having a hollow tubular outer needle as an outlet for the second fluid arranged to coaxially surround the inner needle, an outer needle position adjusting part for adjusting the position of the central axis of the outer needle, and an air nozzle part for gas. a gas injection port for injecting air; a gas ejection means coupled to an end of the outer needle position adjustment unit and configured to generate a current of air moving straight toward charged filaments formed by the spinning solution ejected from a double needle consisting of an outer needle coaxially surrounding the inner needle; and a high voltage application means coupled to the inner nozzle body, wherein the gas ejection means includes a central hole through which the double needle passes and a plurality of gas ejection ports arranged radially around the central hole at a predetermined distance apart.

[0023] The electrospinning nozzle according to the ninth aspect of the present invention is the eighth aspect, characterized in that the outer needle position adjusting part includes a cylindrical position adjusting part body disposed between the outer needle part and the gas ejection means to form a gas flow path, and a plurality of screw pins provided in a part of the position adjusting part body to adjust the central axis of the outer needle.

[0024] The electrospinning nozzle according to a tenth aspect of the present invention is the ninth aspect, wherein the gas inlet is formed at one end of the position adjustment part body, and air injected through the gas inlet is discharged to the gas ejection means.

[0025] The electrospinning nozzle according to an eleventh aspect of the present invention is the tenth aspect, characterized in that a plurality of the screw pins are arranged around the outer needle at a certain angle apart from each other around a portion of the position adjustment unit body.

[0026] The electrospinning nozzle according to the 12th aspect of the present invention is the 11th aspect, characterized in that the inner diameter of the outer needle is 5 μm to 1000 μm larger than the outer diameter of the inner needle, and the distance between the central axis of the inner needle and the central axis of the outer needle is within 0.1 mm.

[0027] The electrospinning nozzle according to a thirteenth aspect of the present invention is the electrospinning nozzle of the twelfth aspect, characterized in that the gas outlet comprises a plurality of air holes, at least two of which are arranged at regular intervals in a plurality of circumferential regions consisting of at least one row of circular lines around the central hole, and which discharge the second fluid, air, to the outside.

[0028] The electrospinning nozzle according to a fourteenth aspect of the present invention is the thirteenth aspect, wherein the gas outlet includes a first gas outlet having at least two air holes arranged in a first circumferential region that is a first circular line spaced apart from the central hole by a radius r1 and surrounding the central hole, and a second gas outlet having at least two air holes arranged in a second circumferential region that is a second circular line spaced apart from the central hole by a radius r2 and surrounding the central hole, wherein the radius r2 of the second circumferential region is greater than the radius r1 of the first circumferential region.

[0029] The electrospinning nozzle according to the 15th aspect of the present invention is the 14th aspect, characterized in that a plurality of nth circumferential regions (where n is a natural number greater than or equal to 3) are further arranged outside the second circumferential region surrounding the second circumferential region, and at least two air holes are arranged in the nth circumferential region.

[0030] The electrospinning nozzle according to a 16th aspect of the present invention is the electrospinning nozzle of the 14th or 15th aspect, characterized in that six air holes are arranged at an angle of 60° to each other in the first circumferential region, the second circumferential region, and the nth circumferential region.

[0031] The electrospinning nozzle according to a seventeenth aspect of the present invention is the electrospinning nozzle of the sixteenth aspect, characterized in that the radius r1 is 3 mm to 5 mm, and the radius r2 is 4 mm to 10 mm.

[0032] The electrospinning nozzle according to an eighteenth aspect of the present invention is the sixteenth aspect, wherein the gas ejection means is an air cap including: a side fastening part coupled to an end extending from the external needle position adjusting part; and a cover part having the central hole and a plurality of gas outlets arranged surrounding the central hole, wherein the side fastening part and the cover part form a retention space for the air inside.

[0033] an outer nozzle body including a second fluid inlet through which a second fluid, i.e., air, is injected; a needle shaft for controlling and blocking the flow of the first fluid transferred to the inner needle body, and a needle shaft seal for preventing the first fluid from flowing back and leaking above the needle shaft; a gas ejection means connected to an end of the outer nozzle body and generating a flow of the second fluid, i.e., air, that moves straight toward a charged filament formed by a spinning solution ejected from the inner needle; and a high-voltage application means connected to the inner nozzle body, wherein the gas ejection means includes a central hole through which the inner needle passes, and a plurality of gas ejections arranged radially around the central hole at predetermined intervals.

[0034] According to a twentieth aspect of the present invention, there is provided an electrospinning nozzle according to the nineteenth aspect, wherein the air pressure control unit body further includes an air inlet for injecting air into the needle shaft, and the needle shaft includes a spring wound around the needle shaft and having elastic restoring force, a tapered blocking portion formed at an end of the needle shaft to block a fluid passage toward the inner needle portion and block the flow of the first fluid, and a pointed-ended shaft needle connected to the tapered blocking portion, penetrating the inner needle and protruding from a tip end thereof.

[0035] The electrospinning nozzle according to a 21st aspect of the present invention is the 20th aspect, characterized in that the gas outlet comprises a plurality of air holes, at least two of which are arranged at regular intervals in a plurality of circumferential regions consisting of at least one row of circular lines around the central hole, and which discharge the second fluid, air, to the outside.

[0036] The electrospinning nozzle according to a 22nd aspect of the present invention is the 21st aspect, wherein the gas outlet includes a first gas outlet having at least two air holes arranged in a first circumferential region that is a first circular line spaced apart from the central hole by a radius r1 and surrounding the central hole, and a second gas outlet having at least two air holes arranged in a second circumferential region that is a second circular line spaced apart from the central hole by a radius r2 and surrounding the central hole, wherein the radius r2 of the second circumferential region is greater than the radius r1 of the first circumferential region.

[0037] The electrospinning nozzle according to the 23rd aspect of the present invention is the 22nd aspect, characterized in that a plurality of nth circumferential regions (where n is a natural number greater than or equal to 3) are further arranged outside the second circumferential region surrounding the second circumferential region, and at least two air holes are arranged in the nth circumferential region.

[0038] The electrospinning nozzle according to a 24th aspect of the present invention is the electrospinning nozzle of the 22nd or 23rd aspect, characterized in that six air holes are arranged at an angle of 60° to each other in the first circumferential region, the second circumferential region, and the nth circumferential region.

[0039] The electrospinning nozzle according to a 25th aspect of the present invention is the 24th aspect, wherein the radius r1 is 3 mm to 5 mm, and the radius r2 is 4 mm to 10 mm.

[0040] The electrospinning nozzle according to a 26th aspect of the present invention is the 24th aspect, characterized in that the gas ejection means is an air cap including: a side fastening part coupled to an end extending from the outer nozzle part body; and a cover part having the central hole and a plurality of gas outlets arranged surrounding the central hole, wherein the side fastening part and the cover part form a retention space for the second fluid, i.e., air. [Effects of the Invention]

[0041] According to one aspect of the present invention, by generating an air flow that moves straight toward the charged filaments formed by the spinning solution discharged from the spinning nozzle for electrospinning, the air flow is prevented from coming into direct contact with the spinning solution, allowing a filament jet to be stably formed at the tip of the spinning nozzle and adjusting the filament jet so that it does not exceed a specific range.

[0042] The following drawings attached to this specification illustrate preferred embodiments of the present invention and, together with the detailed description of the invention, are intended to facilitate a further understanding of the technical concepts of the present invention; therefore, the present invention should not be interpreted as being limited to the matters described in the drawings. [Brief explanation of the drawings]

[0043] [Figure 1] FIG. 1 is a cross-sectional view of an electrospinning nozzle according to a first preferred embodiment of the present invention. [Figure 2] FIG. 2 is a cross-sectional view of the gas ejection means of the electrospinning nozzle of FIG. 1 taken along line AA. [Figure 3] 3 is a vertical cross-sectional view of the gas ejection means taken along line BB in FIG. 2. FIG. [Figure 4] FIG. 2 is a cross-sectional view of an electrospinning nozzle according to a second embodiment of the present invention. [Figure 5] FIG. 10 is a cross-sectional view of an electrospinning nozzle according to a third embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0044] Since the present invention is susceptible to various modifications and embodiments, specific embodiments will be illustrated in the drawings and described in detail. However, the present invention is not limited to the specific embodiments, and it is understood that the present invention includes all modifications, equivalents, and alternatives within the spirit and technical scope of the present invention.

[0045] When a component is said to be "coupled" or "connected" to another component, this includes not only when the component is directly coupled or connected to the other component, but also when there are other components intervening.

[0046] However, when an element is said to be "directly coupled" or "directly connected" to another element, it is understood that there are no other elements intervening therebetween.

[0047] The terms used in this specification are merely used to describe specific embodiments and are not intended to limit the present invention. The singular expressions include the plural expressions unless otherwise clearly indicated in the context. In the present specification, the terms "comprise" or "have" indicate the presence of features, numbers, steps, operations, components, parts, or combinations thereof described in the specification, and do not preclude the presence or additional possibility of one or more other features, numbers, steps, operations, components, parts, or combinations thereof.

[0048] Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by a person of ordinary skill in the art to which this invention pertains. Terms defined in commonly used dictionaries are to be interpreted as meanings consistent with the contextual meaning of the relevant art, and are not to be interpreted in an idealized or overly formal sense unless specifically defined in this application.

[0049] The terms and words used in this specification and claims should not be construed as being limited to their ordinary or dictionary meanings, but should be construed as meanings and concepts that correspond to the technical concepts of the present invention, based on the principle that the inventor himself can appropriately define the concepts of terms in order to best describe his invention. Furthermore, unless otherwise defined, the technical and scientific terms used have the meanings commonly understood by those of ordinary skill in the art to which the present invention pertains. In the following description and the accompanying drawings, descriptions of well-known functions and configurations that may obscure the gist of the present invention will be omitted. The accompanying drawings are provided for illustrative purposes only to fully convey the concepts of the present invention to those skilled in the art. Therefore, the present invention is not limited to the accompanying drawings and may be embodied in other forms. Furthermore, the same reference numerals refer to the same components throughout the specification. Please note that the same reference numerals are used to refer to the same components in the drawings whenever possible.

[0050] DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Preferred embodiments of the present invention will now be described in detail with reference to the accompanying drawings, in which: The drawings are not drawn to scale, and like reference numerals in different drawings refer to like elements.

[0051] First Embodiment FIG. 1 is a cross-sectional view showing the configuration of an electrospinning nozzle equipped with a gas ejection means according to a first embodiment of the present invention.

[0052] Referring to FIG. 1, the electrospinning nozzle 100 according to the present embodiment includes an inner nozzle body 101 into which a spinning solution, which is a first fluid, is injected; an outer nozzle body 102 into which air, which is a second fluid, is injected; an inner needle 103 having a hollow needle 103a which is an outlet for the first fluid; a gas ejection means 104 coupled to the end of the outer nozzle body 102 and generating a flow of air, which is the second fluid, moving straight toward the charged filaments formed by the spinning solution ejected from the hollow needle 103a; and a high voltage application means 106 connected to the inner nozzle body 101.

[0053] The internal nozzle body 101 is composed of a first fluid inlet 101a, which is an inlet through which the first fluid, the spinning solution, is injected, a solution storage space 101b in which the spinning solution flows and accumulates, and a tapered outlet 101c that delivers the spinning solution to the internal needle 103a.

[0054] The inner needle 103 is detachably coupled to the inner nozzle body 101 through an inner needle fastening cap 105 .

[0055] The inner nozzle body 101 may have a screw thread formed on its outer surface for fastening to a specific external fastening part (not shown).

[0056] A syringe or male fitting having a double-threaded luer lock structure outlet, or a tube fastening fitting, may be connected to the first fluid inlet 101a of the inner nozzle body 101. The outlet 101c of the inner nozzle body 101 is configured in a luer taper shape so as to abut and closely couple with the socket portion of the inner needle 103. The solution storage space 101b of the inner nozzle body 101 may be used as a flow path for transporting the spinning solution or as a storage space for temporarily retaining the solution.

[0057] The connection standard of the Luer taper of the outlet 101c of the inner nozzle body 101 is in accordance with the ISO 594 standard {ISO 594-1:1986 "Conical fittings with a 6% (Luer) taper for syringes, needles and certain other medical equipment". [1](https: / / www.iso.org / standard / 4693.html)}.

[0058] The material of the inner nozzle body 101 is preferably a conductive metal such as stainless steel (SUS), aluminum, copper-based material plated with nickel or chromium, brass-based material plated with nickel or chromium, etc. Meanwhile, when the spinning solution as the first fluid is a biopolymer solution containing cells, the material of the inner nozzle body 101 may be a non-metallic material such as a fluorine-based polymer such as Teflon, PEEK (polyether ether ketone), superhard material, or quartz material.

[0059] A high voltage applying means 106 for applying a DC high voltage of several tens to several tens of thousands of volts is connected to the inner nozzle body 101. Therefore, when a high voltage is applied to the inner nozzle body 101, the spinning solution discharged from the tip of the inner needle 103a is charged by the high voltage.

[0060] The inner needle part 103, which is detachably connected to the inner nozzle part body 101 through the inner needle part fastening cap 105, includes a hollow tubular inner needle 103a for discharging the spinning solution to the outside. The inner needle 103a is connected to the inner needle part 103 via a hub or a sleeve.

[0061] The sleeve may be a hollow tube or may be configured as a hollow screw having an external thread. If the sleeve is configured as a soft and elastic polymer, it becomes easier to replace the hollow needle 103a from the internal needle portion 103. For example, the hollow tube-shaped sleeve is preferably configured as a fire-resistant soft material such as fluorinated ethylene propylene (FEP), perfluoroalkoxyalkane (PFA), or polytetrafluoroethylene (PTFE).

[0062] Furthermore, the sleeve may be made of a conductive polymer material containing carbon or a metal component to provide conductivity to the inner needle 103a through the inner nozzle body 101. The inner diameter of the hollow tubular sleeve is preferably approximately the same as or smaller than the outer diameter of the inner needle 103a to ensure excellent adhesion to the inner needle 103a. That is, the hollow tubular sleeve preferably has an inner diameter of 0.05 mm to 4 mm and an outer diameter of 1 mm to 5 mm. The sleeve may be made of a copper-based material or a non-metallic material containing copper. More preferably, the sleeve may be made of a non-ferrous metal such as brass, nickel-plated brass, or copper, or an aluminum-based material, a stainless steel metal, or a moldable polymer such as PEEK.

[0063] The inner needle 103a preferably has an inner diameter of 0.005 mm to 2 mm, an outer diameter of 0.02 mm to 3 mm, and a length of 2 mm to 200 mm. The material of the inner needle 103a is preferably stainless steel (SUS), silica, quartz, super hard, fluorine, or SUS coated with PEEK.

[0064] The tip of the inner needle 103a may be in the form of a blunt end or a pointed end, where the edge angle of the blunt end may be a sharp tip with a 90° angle, a chamfered tip with rounded corners, or a tapered tip with a gradually tapered end.

[0065] An inner needle part fastening cap 105 is used when connecting the inner needle part 103 to the inner nozzle part body 101. The inner needle part fastening cap 105 has a semicircular groove structure on which the hub of the inner needle part 103 is placed or a luer lock structure.

[0066] If the inner needle part fastening cap 105 has a semicircular groove structure, the inner needle part 103 is placed in the groove of the inner needle part fastening cap 105, and then when the cap 105 is turned, the socket part of the hub of the inner needle part 103 is pushed up against the upper end of the taper and abuts against it to be coupled. On the other hand, if the inner needle part fastening cap 105 has a luer lock structure with a double-start screw thread inside, when the hub of the inner needle part 103 is turned, it is pushed up against the upper end of the taper and coupled.

[0067] The outer nozzle body 102 is coupled to the inner nozzle body 101 while surrounding the inner needle 103 and at least a portion of the inner nozzle body 101. The outer nozzle body 102 includes a second fluid inlet 102a for injecting air as a second fluid, and a mounting space in which the inner needle 103 is mounted. The second fluid inlet 102a is configured by a female fitting or a tube fastening fitting coupled to a side portion. The female fitting is preferably made of an insulating material so as not to be affected by an electric field even when a high voltage is applied.

[0068] The gas ejection means 104 is fastened to the lower end of the external nozzle body 102. That is, a fastening tube 102b extending in the longitudinal direction of the nozzle is formed at the lower end of the external nozzle body 102. The fastening tube 102b preferably has an outer diameter smaller than that of the main body of the external nozzle body 102. A screw thread may be formed on the outer surface of the fastening tube 102b for attaching and detaching the gas ejection means 104.

[0069] The gas ejection means 104 is a kind of air cover or air cap that is fastened to the fastening tube 102b of the external nozzle part main body 102 to cover the mounting space of the external nozzle part main body 102 and form a space in which the second fluid, air, is retained.

[0070] The gas ejection means 104 is composed of a side fastening part 104b that is screwed to the fastening tube 102b, and a cover part 104a that covers the installation space and forms an air retention space. The cover part 104a is also formed with a central hole 114 through which the internal needle 103a passes, and a plurality of gas exhaust ports 115 that are arranged surrounding the central hole 114.

[0071] FIG. 2 is a cross-sectional view taken along line AA of the gas ejection means 104 according to the first embodiment of the present invention, and FIG. 3 is a vertical cross-sectional view taken along line BB of the gas ejection means 104 in FIG.

[0072] 2, the gas ejection means 104 is composed of a type of air cap including a central hole 114 through which the inner needle 103a passes and several to several tens of gas ejection ports 115 arranged in at least two circular rows surrounding the central hole 114. The gas ejection ports 115 are air holes for discharging air, which is the second fluid injected through the second fluid inlet 102a, to the outside. As a result, multiple air flowing layers 116 moving in a straight line parallel to the inner needle 103a are formed around the inner needle 103a passing through the central hole 114.

[0073] The gas outlets 115 may be arranged at regular intervals or randomly in a plurality of circumferential regions, each of which comprises at least one circular line centered around the central hole 114. For example, referring to FIG. 2, six first gas outlets 115a are arranged at 60° angles to each other in a first circumferential region 111, which is a first circular line surrounding the central hole 114 and spaced a radius r1 from the central hole 114. Additionally, six second gas outlets 115b are arranged at 60° angles to each other in a second circumferential region 112, which is a second circular line surrounding the central hole 114 and spaced a radius r2 from the central hole 114. In this case, the radius r2 of the second circumferential region 112 is greater than the radius r1 of the first circumferential region 111. That is, the radius r1 is 2 mm to 10 mm, more preferably 3 mm to 5 mm, and the radius r2 is 4 mm to 20 mm, more preferably 4 mm to 10 mm. The gas outlet 115 may be a circular or rectangular hole, but is preferably a circular hole. In this case, if the gas outlet 115 is a circular hole, the diameter of the circular hole is preferably 0.1 mm to 2 mm. The gas outlet 115 may be configured by pressing a hollow needle with an inner diameter of 0.1 mm to 1 mm into the cover part 104a of the gas ejection means 104, instead of a circular hole.

[0074] 2 shows a configuration in which a total of 12 first gas outlets 115a and second gas outlets 115b are arranged in two circular rows around the central hole 114. However, the gas ejection means 104 of the present invention is not necessarily limited to such an arrangement or configuration.

[0075] In this embodiment, a plurality of n-th circumferential regions (where n is a natural number equal to or greater than 3) surrounding the second circumferential region 112 may be further arranged outside the second circumferential region 112. In addition, more than six gas outlets or fewer than six gas outlets may be arranged in the first circumferential region 111, the second circumferential region 112, and the n-th circumferential region (where n is a natural number equal to or greater than 3). In addition, the plurality of gas outlets 115 arranged in one circumferential region may be arranged at a certain angle (e.g., 60°) from each other, or may be arranged randomly without any angular rule.

[0076] The diameter of the central hole 114 is approximately the same as or slightly larger than the outer diameter of the hollow needle 103a that passes through the central hole 114. For example, the diameter of the central hole 114 is preferably 0.001 mm to 0.5 mm larger than the outer diameter of the hollow needle 103a. It is more preferable to set the diameter of the central hole 114 to 0.001 mm to 0.1 mm larger than the outer diameter of the hollow needle 103a to prevent a gap from forming between the central hole 114 and the hollow needle 103a, thereby preventing air, the second fluid, from leaking through the gap. The inlet portion of the central hole 114 through which the internal needle 103a passes is preferably chamfered to allow the internal needle 103a to pass easily. The thickness h1 of the cover portion 104a, which is the bottom surface of the air cap serving as the gas ejection means 104, is preferably 0.1 mm to 5 mm. More preferably, the thickness h1 of the cover portion 104a is 0.5 mm to 2 mm. At this time, if the thickness h1 of the cover portion 104a exceeds 5 mm, it is difficult to drill a small diameter hole.

[0077] In order to prevent leakage of air injected into the external nozzle part body 102, an O-ring may be provided between the fastening tube 102b of the external nozzle part body 102 and the side fastening part 104b of the gas ejection means 104. In this case, the O-ring may be made of a fluorine-based material, Viton (registered trademark), an ethylene-propylene olefin-based material, or a silicone-based material.

[0078] Furthermore, the hollow needle 103a penetrates through the central hole 114 of the air cap (gas ejection means 104) and protrudes, and the protruding length at this time is preferably 1 mm to 10 mm.

[0079] The operation of the electrospinning nozzle according to this embodiment will be described in detail below.

[0080] First, a spinning solution, which is a first fluid, is injected through a first fluid inlet 101a, and the spinning solution is discharged from the tip of an internal needle 103a. At this time, air, which is a second fluid, is injected through a second fluid inlet 102a, and the air is discharged through a plurality of gas outlets 115 provided in an air cap, which is a gas discharge means 104. The spinning solution discharged from the internal needle 103a passes through a conical Taylor cone to generate a filament jet of a certain length, and then passes through a whipping mode in which the filament jet whips suddenly at a specific position, and the solvent evaporates, and the filament jet is deposited as nanofibers in the accumulation portion.

[0081] The filament jet flies within a certain region in the air layer, and the air flow ejected from the gas outlet 115 and moving straight pushes the filament jet toward the accumulating portion within a range spaced a certain distance from the filament jet, forming a straight-moving air flow layer. This prevents the filament jet from excessively spreading or dispersing outward in the whipping mode. The straight-moving air flow concentrates the charged filaments in the whipping mode section. As a result, charged filaments are stably formed from the spinning solution and are concentrated and stacked in the desired stacking region of the accumulating portion.

[0082] Second Embodiment FIG. 4 is a cross-sectional view showing the configuration of an electrospinning nozzle according to a second embodiment of the present invention.

[0083] The electrospinning nozzle 300 according to the second embodiment of the present invention is characterized in that it further includes an outer needle coaxially surrounding the inner needle and an outer needle position adjusting unit for adjusting the position of the central axis of the outer needle, in addition to the configuration of the electrospinning nozzle 100 according to the first embodiment. That is, the electrospinning nozzle 300 according to this embodiment is substantially identical to the electrospinning nozzle 100 according to the first embodiment, except that it further includes an outer needle unit 304 and an outer needle position adjusting unit 306. Therefore, detailed descriptions of the configuration of the electrospinning nozzle 300 according to this embodiment that is the same as that of the electrospinning nozzle 100 according to the first embodiment will be omitted.

[0084] 4, the electrospinning nozzle 300 according to the present embodiment includes an inner nozzle part body 301 into which a first fluid is injected, an outer nozzle part body 302 into which a second fluid is injected, an inner needle part 303 connected to the inner nozzle part body 301 and having a hollow tubular inner needle 303a as an outlet for the first fluid, an outer needle part 304 connected to the outer nozzle part body 302 and having a hollow tubular outer needle 304c as an outlet for the second fluid arranged to coaxially surround the inner needle 303a, an outer needle position adjusting part 306 for adjusting the position of the central axis of the outer needle 304c, a gas ejection means 307 connected to the outer needle position adjusting part 306 for ejecting gas around the double needle consisting of the outer needle 304c coaxially surrounding the inner needle 303a, and a high voltage applying means 308 connected to the inner nozzle part body 301.

[0085] The second fluid to be injected into the outer needle portion 304 is injected through a second fluid inlet 302a, and a gas (eg, air) is injected through a gas inlet 306d.

[0086] The outer needle part 304 includes a holder 304a into which an outer needle 304c having a sleeve 304b is pushed and coupled. A hole (hole) and threads into which the sleeve 304b is pushed are formed in the holder 304a of the outer needle part 304. In this case, it is preferable that the diameter of the hole of the holder 304a is processed to be slightly smaller than the outer diameter of the sleeve 304b so that liquid leakage does not occur after the sleeve 304b of the outer needle 304c is pushed in.

[0087] The opening of the hole in holder 304a is preferably slightly rounded (R-processed) so that sleeve 304b can be easily inserted. If sleeve 304b is threaded, it is preferable to use a unified national fine (UNF) M2 to M5 screw, preferably an M3 screw, to prevent leakage from the thread.

[0088] The external needle position adjustment part 306 includes a cylindrical position adjustment part body 306a that is disposed between the external needle part 304 and the gas ejection means 307 to form a gas flow path, and a plurality of screw pins 306b that are provided in a part of the position adjustment part body 306a and that are used to adjust the central axis of the external needle 304c.

[0089] A gas inlet 306d is connected to one end of the position adjustment part body 306a, and gas (air) injected from the gas inlet 306d is discharged through the gas flow path to a plurality of gas outlets 307a formed in the gas outlet means 307.

[0090] In addition, a fastening tube 306c is formed at the lower end of the position-adjusting unit body 306a to be coupled to a side fastening portion of the gas ejection means 307. That is, the fastening tube 306c extending in the longitudinal direction of the nozzle is formed at the lower end of the position-adjusting unit body 306a. The fastening tube 306c preferably has an outer diameter smaller than that of the position-adjusting unit body 306a. A screw thread may be formed on the outer surface of the fastening tube 306c for attaching and detaching the gas ejection means 307.

[0091] The plurality of screw pins 306b are arranged around a portion of the position adjusting unit body 306a, spaced apart from each other at a predetermined angle (for example, 60° intervals) to surround the outer needle 304c. In this case, the plurality of screw pins 306b may be arranged in a line around the outer needle 304c or in a zigzag pattern.

[0092] At least one, preferably six, screw pins 306b are arranged at 60° intervals to adjust the central axis of the outer needle 304c. At this time, the central position of the outer needle 304c is adjusted to match the central position of the inner needle 303a arranged coaxially inside. By adjusting the central axis of the outer needle 304c relative to the inner needle 303a in this manner, the inner needle 303a and the outer needle 304c can be arranged coaxially or non-coaxially with each other.

[0093] The diameter of the screw pin 306b is preferably 0.5 mm to 5 mm. The tip of the screw pin 306b is preferably pointed or U-shaped. When the inner needle 303a and the outer needle 304c are arranged coaxially, it is preferable to adjust the distance between the central axis of the inner needle 303a and the central axis of the outer needle 304c to within 0.1 mm.

[0094] The outer diameter of the position-adjusting unit body 306a is preferably 5 mm to 50 mm, and the inner diameter is preferably 2 mm to 45 mm. The position-adjusting unit body 306a may be made of any one of SUS metal, aluminum, brass, PEEK, acetal, and nylon. When the position-adjusting unit body 306a is made of an electrically conductive metal material, applying a high voltage to the outer needle position-adjusting unit 306 can achieve stable spinning at the tip of the inner needle 303a.

[0095] In the electrospinning nozzle 300 according to this embodiment, the inner diameter of the outer needle 304c is configured to be 5 μm to 1000 μm larger than the outer diameter of the inner needle 303a. For example, in the electrospinning nozzle according to this embodiment, the inner needle 303a and the outer needle 304c are configured to be 17G-23G [17G (OD: 1.47 mm, ID: 1.07 mm)], 23G (OD: 0.63 mm, ID: 0.33 mm)], 17G-25G [17G (OD: 1.47 mm, ID: 1.07 mm), 25G (OD: 0.50 mm, ID: 0.25 mm)], 18G-25G [18G (OD: 1.27 It is preferable to have any one combination of 21G-27G [21G (OD: 0.80mm, ID: 0.50mm), 27G (OD: 0.40mm, ID: 0.20mm)] and 22G-30G [22G (OD: 0.70mm, ID: 0.40mm), 30G (OD: 0.30mm, ID: 0.15mm)]].

[0096] Gas ejection means 307, which includes a central hole 307d through which outer needle 304c coaxially (or non-coaxially) surrounds inner needle 303a passes and a plurality of gas ejection ports 307a, is connected to a fastening tube 360c formed at the lower end of the position adjustment unit body 306a. The central hole 307d is sealed by fastening a thin silicone plate 307d or an O-ring and a hollow screw 307b. The length by which outer needle 304c protrudes from central hole 307d to the outside is preferably 1 to 10 mm from the lower end of gas ejection means 307.

[0097] The gas ejection means 307 according to this embodiment has the same configuration and function as the gas ejection means 104 shown in FIGS. 2 and 3 of the first embodiment.

[0098] Hereinafter, the operation of the electrospinning nozzle 300 according to this embodiment will be described in detail.

[0099] First, a first spinning solution, which is a first fluid, is injected through a first fluid inlet 301a, and the spinning solution is discharged from the tip of the internal needle 303a. A second fluid, which is a second spinning solution, is injected through a second fluid inlet 302a and discharged to the outside through an external needle 304c. At this time, air is injected through a gas inlet 306d, and the air is discharged through a plurality of gas outlets 307a provided on an air cap, which is a gas discharge means 307. The first spinning solution discharged from the internal needle 303a and the second spinning solution discharged from the external needle 304c pass through a conical Taylor cone to generate a filament jet of a certain length. Then, the filament jet undergoes a whipping mode in which the filament jet rapidly whips at a specific position, and the solvent evaporates, resulting in nanofibers being deposited in the accumulation area.

[0100] The filament jet flies within a certain region in the air layer, and the air flow ejected from the gas outlet 307a and moving straight forms an air fluidized layer moving straight while pushing the filament jet toward the accumulating portion within a range separated by a certain distance from the filament jet, thereby preventing the filament jet from excessively spreading or dispersing outward in the whipping mode. As a result, the spun filaments are laminated as a nanofiber web with a core-shell structure within a desired lamination region of the accumulating portion.

[0101] Third Embodiment FIG. 5 is a cross-sectional view showing the configuration of an electrospinning nozzle 400 according to a third embodiment of the present invention.

[0102] The electrospinning nozzle 400 according to the third embodiment of the present invention is characterized in that it further includes a needle shaft 411 capable of controlling and blocking the flow of the spinning solution during the electrospinning process in addition to the electrospinning nozzle 100 according to the first embodiment. That is, the electrospinning nozzle 400 according to this embodiment is substantially the same as the electrospinning nozzle 100 according to the first embodiment, except that it further includes a needle shaft 411. Therefore, detailed descriptions of the components of the electrospinning nozzle 400 according to this embodiment that are the same as those of the electrospinning nozzle 100 according to the first embodiment will be omitted.

[0103] Referring to FIG. 5, the electrospinning nozzle 400 according to the present embodiment includes an inner nozzle body 401 including a first fluid inlet 401a through which a first fluid is injected, an inner needle part 403 connected to the inner nozzle body 401 and including a hollow tubular inner needle 403b serving as an outlet for the first fluid, an outer nozzle body 402 including a second fluid inlet 402a through which a gas, which is a second fluid, is injected, an air inlet 410a through which air is injected, and a nozzle 410b for controlling the flow of the first fluid transferred to the inner needle part 403. The device includes an air pressure control unit main body 410 including a needle shaft 411 for controlling and blocking, and a needle shaft sealing unit 412 for preventing the first fluid from flowing back and leaking above the needle shaft 411; a gas ejection means 404 including a central hole 404a through which the internal needle 403b passes, and a plurality of gas ejection ports 404b arranged around the central hole 404a for ejecting the second fluid, gas (air), to the outside; and a high voltage application means 406 connected to the internal nozzle unit main body 101.

[0104] In addition, the electrospinning nozzle 400 of this embodiment, like the second embodiment, may further include an outer needle portion having a hollow tubular outer needle connected to the outer nozzle portion body 302 and arranged to coaxially surround the inner needle 403b, and an outer needle position adjustment portion including a plurality of screw pins for adjusting the position of the central axis of the outer needle.

[0105] The needle shaft 411 includes a tapered blocking portion 411a that blocks the fluid passage toward the inner needle portion 403 to block the flow of the first fluid, and a pointed end shaft needle 411b that penetrates the inner needle 403b and protrudes from its tip.

[0106] The needle shaft 411 is normally kept in an upwardly pushed-up state by the spring restoring force of a spring 413 wound around the shaft. As a result, the fluid passage toward the internal needle portion 403 is opened (ON state), allowing the first fluid to flow into the internal needle portion 403. When air is injected through the air inlet 410a, the spring 413 of the needle shaft 411 is compressed by air pressure, and the tapered blocking portion 411a at the tip of the needle shaft 411 blocks the fluid passage for the first fluid. At the same time, the shaft needle 411b penetrates and protrudes through the internal needle 403b, thereby blocking the hollow of the internal needle 403b.

[0107] The operation of the electrospinning nozzle 400 of this embodiment will be described in detail below.

[0108] First, a spinning solution, which is a first fluid, is injected through the first fluid inlet 401a and discharged from the tip of the internal needle 403b. At this time, air is injected through the second fluid inlet 402a, and the air is discharged through multiple gas outlets 404b provided on the air cap, which is the gas discharge means 404. The spinning solution discharged from the internal needle 403b passes through a conical Taylor cone to generate a filament jet of a certain length. The filament jet then undergoes a whipping mode, in which the filament jet whips rapidly at a specific position, causing the solvent to volatilize and form nanofibers in the accumulation portion. Meanwhile, when the first fluid injected through the first fluid inlet 401a is transported to the internal needle 403, the needle shaft seal 412 prevents the first fluid from flowing back and leaking above the internal needle 403.

[0109] The filament jet flies within a certain region in the air layer, and the air flow ejected from the gas outlet 404b moves straight while pushing the filament jet toward the accumulating part within a range separated by a certain distance from the filament jet, thereby preventing the filament jet from spreading or dispersing excessively outward in a whipping mode, thereby enabling the spun filaments to be concentrated and laminated within a desired lamination region of the accumulating part.

[0110] Meanwhile, by injecting air through the air inlet 410a, the spring 413 of the needle shaft 411 is compressed by air pressure, and the tapered blocking portion 411a at the tip of the needle shaft 411 blocks the fluid passage of the first fluid. At the same time, the shaft needle 411b penetrates the inner needle 403b and blocks the passage of the inner needle 403b, thereby blocking the flow of the first fluid (the spinning solution), and the electrospinning process is interrupted. To resume the electrospinning process, the air injected through the air inlet 410a is blocked and air is injected through the second fluid inlet 402a. With the air injected through the air inlet 410a blocked, the spring 413 of the needle shaft 411 returns to its original position due to its spring restoring force, and the fluid passage of the inner needle portion 403 is converted to an open state, and the electrospinning process is resumed.

[0111] In this way, the needle shaft 411 can easily control the on / off of the flow of the spinning solution injected into the first fluid inlet 401a.

[0112] The air injected from the outside through the air inlet 410 a to control the needle shaft 411 needs to be injected with a pressure equal to or greater than the spring restoring force (tension) of the spring 413 .

[0113] In addition, if the electrospinning nozzle 400 of this embodiment further includes an outer needle coaxially surrounding the inner needle 403b, it may further include a separate gas inlet for injecting another spinning solution into the second fluid inlet 402a and for injecting air ejected from the gas outlet 404b.

[0114] As described above, the present invention has been described using limited embodiments and drawings, but the present invention is not limited thereto, and it goes without saying that various modifications and variations can be made by a person having ordinary knowledge in the technical field to which the present invention pertains within the technical spirit of the present invention and the equivalent scope of the claims. [Industrial Applicability]

[0115] According to an electrospinning apparatus using an electrospinning nozzle according to one embodiment of the present invention, a nanofiber web having micropores can be produced. The nanofiber web can be used as a waterproof and breathable membrane, a filter material for filtering ultrafine dust particles, a scaffold for cell culture, a drug-carrying patch, a sensor material having a high specific surface area, and a flexible electronic material.

Claims

1. an inner nozzle body into which a spinning solution, which is a first fluid, is injected; an inner needle portion connected to the inner nozzle portion body and including a hollow tubular inner needle that is an outlet for the first fluid; an external nozzle body into which air, which is the second fluid, is injected; a gas ejection means coupled to an end of the outer nozzle body, for generating a flow of air as the second fluid that moves in a straight line toward the charged filament formed by the spinning solution discharged from the inner needle; a high voltage applying means connected to the inner nozzle body, The gas ejection means includes a central hole through which the inner needle passes, and a plurality of gas ejection ports arranged radially around the central hole at a predetermined distance apart.

2. 2. The electrospinning nozzle of claim 1, wherein the gas outlet comprises a plurality of air holes, at least two of which are arranged at regular intervals in a plurality of circumferential regions formed by at least one row of circular lines around the central hole, and which discharge the second fluid, air, to the outside.

3. The gas outlet is The radius r from the central hole １ a first gas outlet in which at least two air holes are arranged in a first circumferential region, which is a first circular line surrounding the central hole and spaced apart by a distance of The radius r from the central hole ２ a second gas outlet in which at least two air holes are arranged in a second circumferential region that is a second circular line surrounding the central hole and spaced apart by a distance of the radius r of the second circumferential region ２ is the radius r of the first circumferential region １ 3. The electrospinning nozzle of claim 2, wherein

4. a plurality of n-th circumferential regions are further disposed outside the second circumferential region and surrounding the second circumferential region, where n is a natural number equal to or greater than 3; 4. The electrospinning nozzle of claim 3, wherein at least two air holes are arranged in the nth circumferential region.

5. 5. The electrospinning nozzle according to claim 3, wherein six air holes are arranged at an angle of 60° to each other in the first circumferential region, the second circumferential region, and the nth circumferential region.

6. The radius r １ is 3 mm to 5 mm, and the radius r ２ The electrospinning nozzle of claim 5, wherein is 4 mm to 10 mm.

7. The gas ejection means is a side fastening part coupled to an end extending from the external nozzle part body; and a cover part having the central hole and a plurality of gas discharge ports arranged to surround the central hole, The electrospinning nozzle of claim 5 , wherein the side fastening portion and the cover portion form an air cap inside which a retaining space for the second fluid, i.e., air, is formed.

8. an internal nozzle body into which a first fluid is injected; an inner needle portion connected to the inner nozzle portion body and including a hollow tubular inner needle that is an outlet for the first fluid; an external nozzle body into which the second fluid is injected; an outer needle portion including a hollow tubular outer needle that is connected to the outer nozzle portion body and that is an outlet for the second fluid and that is arranged so as to coaxially surround the inner needle; an outer needle position adjusting unit that adjusts the position of the central axis of the outer needle; a gas inlet for injecting air, which is a gas; a gas ejection means coupled to an end of the outer needle position adjusting unit, for generating an air flow that moves in a straight line toward the charged filaments formed by the spinning solution ejected from a double needle consisting of an outer needle coaxially surrounding the inner needle; a high voltage applying means connected to the inner nozzle body, The gas ejection means includes a central hole through which the double needle passes, and a plurality of gas ejection ports arranged radially around the central hole at a predetermined distance apart.

9. The external needle position adjustment unit a cylindrical position adjustment unit body that is disposed between the external needle portion and the gas ejection means and forms a gas flow path; The electrospinning nozzle of claim 8 , further comprising: a plurality of screw pins provided in a portion of the position adjusting portion body for adjusting the central axis of the outer needle.

10. The gas inlet is formed at one end of the position adjustment unit body, The electrospinning nozzle according to claim 9 , wherein the air injected through the gas inlet is discharged to the gas ejection means.

11. The electrospinning nozzle according to claim 10 , wherein the plurality of screw pins are arranged around the outer needle at a certain angular interval around a portion of the position adjustment unit body.

12. The inner diameter of the outer needle is configured to be 5 μm to 1000 μm larger than the outer diameter of the inner needle; 12. The electrospinning nozzle of claim 11, wherein the distance between the central axis of the inner needle and the central axis of the outer needle is within 0.1 mm.

13. 13. The electrospinning nozzle of claim 12, wherein the gas outlet comprises a plurality of air holes, at least two of which are arranged at regular intervals in a plurality of circumferential regions formed by at least one row of circular lines around the central hole, and which discharge the second fluid, air, to the outside.

14. The gas outlet is The radius r from the central hole １ a first gas outlet in which at least two air holes are arranged in a first circumferential region, which is a first circular line surrounding the central hole and spaced apart by a distance of The radius r from the central hole ２ a second gas outlet in which at least two air holes are arranged in a second circumferential region that is a second circular line surrounding the central hole and spaced apart by a distance of the radius r of the second circumferential region ２ is the radius r of the first circumferential region １ 14. The electrospinning nozzle of claim 13, wherein

15. a plurality of n-th circumferential regions are further disposed outside the second circumferential region and surrounding the second circumferential region, where n is a natural number equal to or greater than 3; 15. The electrospinning nozzle of claim 14, wherein at least two air holes are arranged in the nth circumferential region.

16. 16. The electrospinning nozzle of claim 14, wherein six air holes are arranged at an angle of 60° to each other in the first circumferential region, the second circumferential region, and the nth circumferential region.

17. The radius r １ is 3 mm to 5 mm, and the radius r ２ The electrospinning nozzle of claim 16, wherein is 4 mm to 10 mm.

18. The gas ejection means is a side fastening part coupled to an end extending from the external needle position adjusting part; and a cover part having the central hole and a plurality of gas discharge ports arranged to surround the central hole, The electrospinning nozzle of claim 16, wherein the nozzle is an air cap in which the air retention space is formed by the side fastening portion and the cover portion.

19. an inner nozzle portion body including a first fluid inlet through which a first fluid is injected; an inner needle portion connected to the inner nozzle portion body and including a hollow tubular inner needle that is an outlet for the first fluid; an external nozzle body including a second fluid inlet through which air, which is a second fluid, is injected; an air pressure control unit body including a needle shaft for controlling and blocking the flow of the first fluid transferred to the internal needle portion, and a needle shaft sealing portion for preventing the first fluid from flowing back and leaking above the needle shaft; a gas ejection means coupled to an end of the outer nozzle body, for generating a flow of air as the second fluid that moves in a straight line toward the charged filament formed by the spinning solution discharged from the inner needle; a high voltage applying means connected to the inner nozzle body, The gas ejection means includes a central hole through which the inner needle passes, and a plurality of gas ejection ports arranged radially around the central hole at a predetermined distance apart.

20. the air pressure control unit body further includes an air inlet for injecting air into the needle shaft; The needle shaft a spring wound around the needle shaft and having an elastic restoring force; a tapered blocking portion formed at the distal end of the needle shaft for blocking a fluid passage toward the internal needle portion and thereby blocking the flow of the first fluid; 20. The electrospinning nozzle of claim 19, comprising: a pointed-ended shaft needle connected to the tapered interruption and extending through the inner needle and protruding from its tip.

21. 21. The electrospinning nozzle of claim 20, wherein the gas outlet comprises a plurality of air holes, at least two of which are arranged at regular intervals in a plurality of circumferential regions formed by at least one row of circular lines around the central hole, and which discharge the second fluid, air, to the outside.

22. The gas outlet is The radius r from the central hole １ a first gas outlet in which at least two air holes are arranged in a first circumferential region, which is a first circular line surrounding the central hole and spaced apart by a distance of The radius r from the central hole ２ a second gas outlet in which at least two air holes are arranged in a second circumferential region that is a second circular line surrounding the central hole and spaced apart by a distance of The radius r of the second circumferential region ２ is the radius r of the first circumferential region １ 22. The electrospinning nozzle of claim 21 , wherein

23. a plurality of n-th circumferential regions are further disposed outside the second circumferential region and surrounding the second circumferential region, where n is a natural number equal to or greater than 3; 23. The electrospinning nozzle of claim 22, wherein at least two air holes are disposed in the nth circumferential region.

24. 24. The electrospinning nozzle of claim 22 or 23, wherein six air holes are arranged at an angle of 60° to each other in the first circumferential region, the second circumferential region, and the nth circumferential region.

25. The radius r １ is 3 mm to 5 mm, and the radius r ２ The electrospinning nozzle of claim 24, wherein is 4 mm to 10 mm.

26. The gas ejection means is a side fastening part coupled to an end extending from the external nozzle part body; and a cover part having the central hole and a plurality of gas discharge ports arranged to surround the central hole, The electrospinning nozzle of claim 24, wherein the side fastening portion and the cover portion form an air cap inside which a retaining space for the second fluid, i.e., air, is formed.

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