Moisture-retaining fabric and its use

Abstract

The present invention relates to a fabric comprising a first yarn comprising polylactic acid (PLA) fibres, a second yarn comprising elastic fibres or regenerated cellulose fibres, and a third yarn comprising regenerated cellulose fibres, and its use for the treatment of dermatitis.

Description

[Technical Field]

[0001]

[0001] This application claims priority to Australian Provisional Patent Application No. 2022902911, filed on 6 October 2022, the entire disclosure of which is incorporated herein by cross-reference.

[0002] Field of Disclosure

[0002] The present disclosure relates generally to moisturizing fabrics and their use in treating skin conditions. [Background technology]

[0003] Background to the disclosure

[0003] Any discussion of prior art throughout this specification should in no way be taken as an admission that such prior art is widely known or forms part of the common general knowledge in the field.

[0004]

[0004] There is a growing need for moisturizing fabrics in the medical apparel market. Garments based on such fabrics can be effective in preventing dry skin, improving the body's sweating mechanism, and alleviating the symptoms of skin disorders such as eczema.

[0005]

[0005] Eczema, also known as atopic dermatitis, is a chronic inflammatory skin disease. It is a common disease and requires long-term treatment. Eczema patients may have skin barrier dysfunction, alloknesis, chronic inflammation, and an imbalance in the intestinal flora. The main strategies for treating eczema include (i) topical corticosteroids and tacrolimus ointment to suppress inflammation, (ii) topical emollients to treat physiological abnormalities in the skin, and (iii) identifying and avoiding exacerbating factors in daily life.

[0006]

[0006] In the long-term management of eczema, it is particularly important to address aggravating factors in daily life. Aggravating factors include temperature, sweating, clothing fabric, stress, food, alcohol consumption, and poor physical condition. Among these factors, temperature, sweating, and clothing fabric can be improved by changing clothing fabric. Furthermore, since fabrics are in contact with human skin for long periods of time, fabrics are an important component of the skin environment. Therefore, selecting appropriate fabrics is an important treatment for eczema patients.

[0007]

[0007] Other existing treatments for eczema include applying water directly to the skin with an applicator such as a bandage. However, direct contact between the skin and water leads to wrinkling of the outer layer of the skin due to the breakdown of the stratum corneum's structure. Furthermore, applied water can also disrupt the pH of the skin's acid mantle (which has a pH of approximately 4.5 to 6.5). Maintaining the acid mantle is important for skin health due to its ability to repel bacteria and reduce the risk of skin infection.

[0008]

[0008] The present inventors have developed a fabric suitable for use in moisturizing clothing applications that can rapidly absorb sweat and efficiently transport it to the outer surface of the fabric, where it is retained. Such a fabric can provide moisturizing benefits to the skin without causing the wearer to feel wet or clammy. Summary of the Invention [Means for solving the problem]

[0009] Disclosure Overview In a first aspect, the present disclosure provides a method for manufacturing a semiconductor device, comprising: a first yarn comprising polylactic acid (PLA) fibers; a second yarn comprising elastic fibers or regenerated cellulose fibers; a third yarn containing regenerated cellulose fibers; A fabric comprising:

[0010]

[0010] The following options may be used individually or in any combination in conjunction with the first aspect of the present disclosure.

[0011] In one embodiment, the fabric of the first aspect of the present disclosure comprises: a first yarn comprising polylactic acid (PLA) fibers; a second yarn comprising an elastic fiber; a third yarn containing regenerated cellulose fibers; Includes:

[0012] In one embodiment, the fabric of the first aspect of the present disclosure comprises: a first yarn comprising polylactic acid (PLA) fibers; a second yarn comprising regenerated cellulose fibers; a third yarn containing regenerated cellulose fibers; Includes:

[0013] In one embodiment, the fabric of the first aspect of the present disclosure comprises: a first yarn made of polylactic acid (PLA) fiber; a second yarn made of an elastoolefin fiber; a third thread made of regenerated cellulose fibers; It consists of:

[0014] In one embodiment, the fabric of the first aspect of the present disclosure comprises: a first yarn made of polylactic acid (PLA) fiber; a second yarn made of elastic fiber; a third thread made of regenerated cellulose fibers; Includes:

[0015] In one embodiment, the fabric of the first aspect of the present disclosure comprises: a first yarn made of polylactic acid (PLA) fiber; a second yarn made of an elastoolefin fiber; a third yarn containing regenerated cellulose fibers; Includes:

[0016]

[0016] The first yarn may be a filament yarn.

[0017]

[0017] The cross section of the PLA fiber can be X-shaped.

[0018]

[0018] The first yarn may be about 40 denier to about 150 denier, or about 40 denier to about 85 denier, or about 50 denier to about 75 denier, or about 50 denier, or about 75 denier. The filament fineness of the first yarn may be about 1 denier to about 2 denier, or about 1 denier to about 1.5 denier, or about 1.2 denier. The first yarn may have a diameter of about 70 to about 100 μm or about 91 μm. The first yarn may have a diameter of about 30 to about 60 μm or about 46 μm.

[0019]

[0019] The first yarn may have a stitch length / 100 loops of about 20 cm to about 40 cm or about 25 cm to about 35 cm.

[0020] The first yarns may comprise about 15% to about 60% by weight of the fabric, or about 30% to about 60% by weight of the fabric, or about 35% to about 55% by weight of the fabric. The first yarns may comprise about 45% by weight of the fabric. The first yarns may comprise about 47% by weight of the fabric.

[0021]

[0021] The first thread may be made of PLA fibers.

[0022]

[0022] The first yarn, when in contact with the wearer's skin during use, may protect the wearer from sweat.

[0023]

[0023] The second yarn may be a filament yarn.

[0024] The second yarn may be about 25 denier to about 65 denier, or about 33 denier to about 55 denier, or about 33 denier, or about 42 denier, or about 55 denier. The second yarn may have a diameter of about 60 to about 90 μm or about 73 μm. The second yarn may have a diameter of about 20 to about 50 μm or about 36 μm.

[0025]

[0025] The second yarn may have a stitch length / 100 loops of about 5 cm to about 20 cm or about 10 cm to about 15 cm.

[0026] The second yarn may comprise about 5% to about 20% by weight of the fabric, or about 8% to about 15% by weight of the fabric. The second yarn may comprise about 12% by weight of the fabric. The second yarn may comprise about 9% by weight of the fabric.

[0027]

[0027] The elastic fiber may be selected from the group consisting of elastoolefin, elastane, diene elastic fiber, polyetherester elastic fiber, and polyolefin elastomeric fiber. The elastic fiber may be elastane. The second yarn may comprise or consist of elastane.

[0028] In some embodiments, particularly when the fabric does not need to be elastic, the second yarn can have the same composition as the third yarn. The second yarn can be a spun yarn having the same composition as the third yarn. That is, the second yarn can include regenerated cellulose fibers as defined for the third yarn.

[0029] The third yarn may have a moisture regain of about 10% to about 20% or about 13%.

[0030]

[0030] The third yarn may be a spun yarn.

[0031]

[0031] The third yarn may further comprise polyester or cotton.

[0032]

[0032] The regenerated cellulose fibers can be modal, tencel, rayon, cuprammonium fibers or combinations thereof.

[0033]

[0033] The regenerated cellulose fibers may be modal.

[0034]

[0034] The third yarn may be made of modal.

[0035]

[0035] The third yarn may comprise about 30% to about 80% by weight of the fabric, about 30% to about 60% by weight of the fabric, or about 33% to about 53% by weight of the fabric. The third yarn may comprise about 43% by weight of the fabric. The third yarn may comprise about 44% by weight of the fabric.

[0036]

[0036] The third yarn may have a stitch length / 100 loops of about 20 cm to about 40 cm or about 26 cm to about 36 cm.

[0037] The third yarn may have a thread count of about 30 tex to about 5 tex, about 10 tex to about 7 tex, or about 5 tex to about 7 tex, or about 9.7 tex, 8.3 tex, or 7.3 tex. The third yarn may have a diameter of about 60 to about 90 μm, or about 79 μm. The third yarn may have a diameter of about 20 to about 50 μm, or about 39 μm.

[0038]

[0038] The third thread receives and holds the sweat removed from the wearer's skin, preventing it from coming into contact with the wearer's skin, thus removing the sweat from the skin.

[0039]

[0039] Sweat captured by the third yarn can generate water vapor, which provides a moisturizing effect to the wearer's skin without giving the wearer a clammy feeling.

[0040]

[0040] The second yarn may be interwoven between the first yarn and the third yarn.

[0041]

[0041] The first, second and third yarns may be present as layers.

[0042]

[0042] The fabric may consist of three layers.

[0043]

[0043] The first yarn may form the bottom layer, the second yarn may form the middle layer, and the third yarn may form the top layer.

[0044]

[0044] In one embodiment, the fabric is a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric adapted to contact the skin of a wearer; a second yarn comprising elastic fibers or regenerated cellulose fibers, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an uppermost outer layer of the fabric that is furthest from the wearer's skin; and It may comprise or consist of:

[0045]

[0045] In one embodiment, the fabric comprises: a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric adapted to contact the skin of a wearer; a second yarn comprising an elastic fiber, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an uppermost outer layer of the fabric that is furthest from the wearer's skin; and It may comprise or consist of:

[0046]

[0046] In one embodiment, the fabric comprises: a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric adapted to contact the skin of a wearer; a second yarn comprising regenerated cellulose fibers, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an uppermost outer layer of the fabric that is furthest from the wearer's skin; and It may comprise or consist of:

[0047]

[0047] The fabric may be a knitted fabric.

[0048]

[0048] The knitted fabric may be a jersey fabric, which may be a single knit or double knit fabric.

[0049]

[0049] The dough may be a moisturizing dough.

[0050] In a second aspect, the present disclosure provides an article of clothing when produced from or includes the fabric of the first aspect of the present disclosure.

[0051]

[0051] The following options may be used individually or in any combination in conjunction with the second aspect of the present disclosure.

[0052] In one embodiment, the article of apparel of the second aspect of the present disclosure is a fabric comprising: a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric adapted to contact the skin of a wearer; a second yarn comprising an elastic fiber, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an uppermost outer layer of the fabric that is furthest from the wearer's skin; and Produced from or comprising a fabric comprising or consisting of

[0053]

[0053] The article of clothing may be a shirt, running shirt, jersey, pajamas, maillot, fleece, shorts, pants, a hood, running hat, skull cap, helmet liner, mask, headband or socks.

[0054] In a third aspect, the present disclosure provides a method of treating dermatitis in a subject in need thereof, the method comprising applying the fabric of the first aspect or the article of clothing of the second aspect to an area of ​​the subject's body suffering from the dermatitis. The dermatitis may be atopic dermatitis, i.e., eczema.

[0055]

[0055] In a fourth aspect, the present disclosure provides the fabric of the first aspect or the garment of the second aspect for use in treating dermatitis in a subject in need thereof.

[0056]

[0056] In a fifth aspect, the present disclosure provides use of the fabric of the first aspect in the manufacture of an article of clothing for treating dermatitis in a subject in need thereof. The dermatitis may be atopic dermatitis, i.e., eczema.

[0057] definition

[0057] Throughout this specification, unless the context requires otherwise, the word "comprise" or variations such as "comprises" or "comprising" will be understood to imply the inclusion of a stated element, integer or step or group of elements, integers or steps, but not the exclusion of any other element, integer or step or group of elements, integers or steps. Thus, in the context of this specification, the term "comprise" means "including primarily, but not necessarily only."

[0058] In the context of this specification, the terms "a" and "an" are used herein to refer to one or to more than one (i.e., to at least one) of the grammatical object of the term. By way of example, "an element" means one element or more than one element.

[0059]

[0059] The term "about" is understood to refer to a range of numbers that one of ordinary skill in the art would consider equivalent to the recited value in the context to achieve the same function or result.

[0060]

[0060] In the context of this specification, the term "yarn" is understood to mean a continuous length of intertwined fibres that can be made into a textile material.

[0061]

[0061] In the context of this specification, the term "filament yarn" is understood to mean a yarn made of one or more continuous fibers in the form of filaments, each filament extending the entire length of the yarn.

[0062]

[0062] In the context of this specification, the term "spun yarn" is understood to mean staple length fibers twisted or spun together to form a continuous strand.

[0063]

[0063] In the context of this specification, yarn may refer to a single strand yarn, a double strand yarn or a more than double strand yarn.

[0064]

[0064] In the context of this specification, the term "denier" refers to a unit of measure for the linear mass density of a fiber, defined as the mass in grams per 9000 meters of fiber.

[0065] In the context of this specification, "S" refers to British yarn count, which provides the number of strands per pound of British mass of 840 yards. For example, 60S means that 60 strands of 840 yards length weigh 1 pound. The corresponding SI unit is "tex", where for cellulosic yarns 1 tex = 583.1 / S and for synthetic yarns 1 tex = 590.5 / S.

[0066]

[0066] In the context of this specification, the terms "treat" and "treatment" refer to any use that ameliorates a particular disease or condition or its symptoms, or otherwise hinders, slows, or stops the progression of a particular disease or condition or other undesirable symptoms thereof, regardless of the method. Thus, the terms "treat" and "treatment" are to be considered in their broadest context. For example, treatment does not necessarily imply that a subject is treated until complete recovery.

[0067]

[0067] In the context of this specification, the terms "eczema" and "atopic dermatitis" are used interchangeably and refer to inflammation of the skin that causes dryness, itching, swelling, redness and / or cracking.

[0068] BRIEF DESCRIPTION OF THE DRAWINGS

[0068] Embodiments of the present disclosure will now be described, by way of example only, with reference to the accompanying drawings, in which: [Brief explanation of the drawings]

[0069] [Figure 1]

[0069] Schematic diagram of fabric structure. [Figure 2a]

[0070] Fabric surface under 100x magnification. [Figure 2b]

[0070] Surface of fabric under 100x magnification. [Figure 3a]

[0071] The back of the fabric under 100x magnification. [Figure 3b]

[0071] Back of fabric under 100x magnification. [Figure 4]

[0072] Side view of fabric under magnification. [Figure 5]

[0073] Schematic diagram of clothing-people-environment. [Figure 6a]

[0074] A shirt made using the fabric according to the first aspect of the present disclosure. [Figure 6b]

[0074] A shirt made using the fabric according to the first aspect of the present disclosure. A summer shirt. [Figure 7]

[0075] Schematic diagram of the study protocol. [Figure 8]

[0076] Research results. (a) EASI measurement values ​​before and after wearing a T-shirt in summer and winter. (b) POEM measurement values ​​before and after wearing a T-shirt in summer and winter. (c) Itch VAS measurement values ​​before and after wearing a T-shirt in summer and winter. (d) Skin pH measurement values ​​before and after wearing a T-shirt in summer and winter. (e) SCWC measurement values ​​before and after wearing a T-shirt in summer and winter. (f) TSQM-9 score before and after wearing a T-shirt in summer and winter. DETAILED DESCRIPTION OF THE INVENTION

[0070] Detailed Description

[0077] In one aspect, the present disclosure provides a method for manufacturing a semiconductor device comprising: a first yarn comprising polylactic acid (PLA) fibers; a second yarn comprising elastic fibers or regenerated cellulose fibers; a third yarn containing regenerated cellulose fibers; The present invention provides a dough comprising or consisting of:

[0071]

[0078] The first yarn may include PLA fibers. In some embodiments, the first yarn may be made of PLA fibers. PLA is a hydrophobic fiber with a low moisture content, which promotes the expulsion of sweat moisture from the skin and increases evaporation. Efficient drying of sweat can keep the skin surface dry and prevent eczema from worsening. PLA also has a pH value of 5.5, which is close to the natural pH of skin and is non-allergenic. Therefore, in some embodiments, the fabric of the first aspect of the present disclosure does not contain any additives for pH adjustment.

[0072]

[0079] In some embodiments, the first yarn can be about 40 denier to about 150 denier, about 40 denier to about 85 denier, or about 40 denier to about 80 denier, or about 45 denier to about 75 denier, or about 50 denier to about 75 denier, or about 50 denier, or about 75 denier. The filament fineness of the first yarn can be about 1 denier to about 2 denier, or about 1 denier to about 1.5 denier, or about 1.2 denier. The first thread may have a diameter of about 30 to about 100 μm, or about 30 to 40, 30 to 50, 30 to 60, 30 to 70, 30 to 80, 30 to 90, 40 to 50, 40 to 60, 40 to 70, 40 to 80, 40 to 90, 40 to 100, 50 to 60, 50 to 70, 50 to 80, 50 to 90, 50 to 100, 60 to 70, 60 to 80, 60 to 90, 60 to 100, 70 to 80, 70 to 90, 80 to 90, 80 to 100, or about 90 to about 100 μm.The first thread may have a diameter of about 30 μm, or about 40, 50, 60, 70, 80, 90, or about 100 μm. The first thread may have a diameter of about 91 μm or about 46 μm.

[0073]

[0080] In some embodiments, the first yarns may comprise about 15% to about 60% by weight of the fabric, or about 30% to about 60% by weight of the fabric, or about 35% to about 55% by weight of the fabric. The first yarns may comprise about 45% by weight of the fabric. The first yarns may comprise about 47% by weight of the fabric.

[0074]

[0081] The second yarn comprises or consists of an elastic fiber. Any suitable elastic fiber may be used, which contributes to the elastic properties of the fabric. Suitable elastic fibers include elastoolefins, elastane, diene elastic fibers, polyetherester elastic fibers, and polyolefin elastomeric fibers. Elastoolefins are fibers containing 95% by weight of a partially crosslinked polymer made of ethylene and at least one other olefin. Elastoolefins rapidly recover to their original length when stretched 1.5 times their original length. Elastane is a polyether-polyurea copolymer fiber, also known as spandex under the trade name Lycra®. In some embodiments, the second yarn comprises an elastoolefin. In some embodiments, the second yarn consists of an elastoolefin. In some embodiments, the second yarn comprises elastane. In some embodiments, the second yarn consists of elastane.

[0075]

[0082] In some embodiments, the second yarn can be from about 25 denier to about 65 denier, or from about 30 denier to about 60 denier, or from about 33 denier to about 55 denier, or about 33 denier, or about 42 denier, or about 55 denier. The second thread may have a diameter of about 20 to about 90 μm, or about 20 to 30, 20 to 40, 20 to 50, 20 to 60, 20 to 70, 20 to 80, 30 to 40, 30 to 50, 30 to 60, 30 to 70, 30 to 80, 30 to 90, 40 to 50, 40 to 60, 40 to 70, 40 to 80, 40 to 90, 50 to 60, 50 to 70, 50 to 80, 50 to 90, 60 to 70, 60 to 80, 70 to 80, 70 to 90, or about 80 to about 90 μm. The second thread may have a diameter of about 30 μm, or about 40, 50, 60, 70, 80, or about 90 μm. The second thread may have a diameter of about 73 μm. The second thread may have a diameter of about 36 μm.

[0076]

[0083] In some embodiments, the second yarns may comprise about 5% to about 20% by weight of the fabric, or about 8% to about 15% by weight of the fabric. The second yarns may comprise about 12% by weight of the fabric. The second yarns may comprise about 9% by weight of the fabric.

[0077]

[0084] In some embodiments, where the fabric does not need to be particularly elastic, the second yarn can have the same composition as the third yarn. The second yarn can be a spun yarn having the same composition as the third yarn. That is, the second yarn can include regenerated cellulose fibers as defined for the third yarn. In some embodiments, when the second yarn includes regenerated cellulose fibers, the regenerated cellulose fibers are modal. In terms of fabric functionality, the regenerated cellulose fibers connect the first and third yarns (top and bottom layers) and allow moisture to diffuse from the bottom layer to the top layer. The regenerated cellulose fibers also contribute to the aesthetic appearance of the fabric by providing thickness and stiffness.

[0078]

[0085] The third yarn comprises or consists of regenerated cellulose fibers. Regenerated cellulose fibers are made from cellulose extracted from wood pulp, cotton, bamboo, or any other cellulose source, which is chemically dissolved and then extruded. In some embodiments, the regenerated cellulose fibers are modal, Tencel, rayon, cuprammonium fiber, cotton, bamboo, or combinations thereof. In one embodiment, the regenerated cellulose fibers can be modal fibers. In one embodiment, the third yarn can consist of modal fibers.

[0079]

[0086] The third yarn may comprise about 30% to about 80% by weight of the fabric, about 30% to about 60% by weight of the fabric, or about 33% to about 53% by weight of the fabric. The third yarn may comprise about 43% by weight of the fabric. The third yarn may comprise about 44% by weight of the fabric.

[0080]

[0087] The third yarn can have a thread count of about 20 S to about 100 S, about 60 S to about 80 S, or about 20 S, 30 S, 40 S, 50 S, 60 S, 70 S, or 80 S. Equivalently, the third yarn can have a thread count of about 5 tex to about 30 tex, about 10 tex to about 7 tex, or about 9.7 tex, 8.3 tex, or 7.3 tex. The third thread may have a diameter of about 20 to about 90 μm, or about 20 to 30, 20 to 40, 20 to 50, 20 to 60, 20 to 70, 20 to 80, 30 to 40, 30 to 50, 30 to 60, 30 to 70, 30 to 80, 30 to 90, 40 to 50, 40 to 60, 40 to 70, 40 to 80, 40 to 90, 50 to 60, 50 to 70, 50 to 80, 50 to 90, 60 to 70, 60 to 80, 70 to 80, 70 to 90, or about 80 to about 90 μm. The second thread may have a diameter of about 20 μm, or about 30, 40, 50, 60, 70, 80, or about 90 μm. The second thread may have a diameter of about 79 μm. The second thread may have a diameter of about 39 μm.

[0081]

[0088] The third yarn may have a moisture regain of about 10% to about 20%, or about 10% to about 15%, or about 11% to about 14%, or about 12% to about 14%, or about 13%. Moisture regain is defined as the weight of water present in a material expressed as a percentage of the oven-dry weight. Thus, moisture regain (R) is: R=W / D×100 where W is the weight of water and D is the oven dry weight. It is calculated as follows:

[0082]

[0089] The third yarn may further comprise polyester or cotton.

[0083]

[0090] The first, second, and third yarns can be present as layers in the fabric, for example, as shown in Figures 1-4. In some embodiments, the first yarn can form a bottom layer, the second yarn can form a middle layer, and the third yarn can form a top layer. In some embodiments, the fabric can include or consist of three layers.

[0084]

[0091] The fabric of the first embodiment of the present disclosure is structured to optimally maintain a moist environment, especially for the skin. A unique dynamic system between the human, clothing, and the environment is predicted to yield optimal results. Two types of permeation occur in the dynamic human-clothing-environment system shown in Figure 5. The first permeation (B) occurs when the area between the fabric and the skin is less humid than the human skin, causing water loss from the skin to the area between the fabric and the skin (transepidermal water loss, TEWL). TEWL refers to the loss of water vapor through the skin, not the secretion of liquid sweat. This area between the fabric and the skin forms a microclimate. The second permeation (A) occurs in the fabric, with a layer of crystalline water on the fiber surface acting as a membrane between the external environment and the microclimate. When the microclimate is humid, water vapor moves to the external environment. According to TEWL, a continuous supply of water is transferred to the microclimate. It is hypothesized that if System A can slow water loss from the microclimate to the external environment, it can provide a moisturizing effect to the skin. The presence of external pressure from the environment helps slow water loss from the microclimate to the outside world. Microclimate changes are dynamic and stabilized. This is consistent with the research detailed in the Examples below. It has been found that applying an oil-containing moisturizer to the skin can help maintain skin hydration by reducing TEWL. Instead of applying an oil-containing moisturizer to the skin, the fabric has a skin care function by functioning like a moisturizer. The fabric acts like a membrane during the penetration process, creating osmotic pressure from A to B as shown in Figure 5, thereby slowing the water loss process. This occurs when crystalline water fills the gaps between the regenerated fibers of the third yarn after absorption, thereby minimizing the space remaining for water loss. This layer of crystalline water on the surface of the fibers of the third yarn helps retain water vapor within the skin by slowing its penetration from the wearer's body to the external environment, just like a layer of oil applied directly to the skin surface to reduce TEWL.

[0085]

[0092] The hydrophilic top layer utilizes the human sweating mechanism to provide continuous insulation by replenishing moisture through the absorption of liquid and vapor sweat. Furthermore, the hydrophilic top layer increases the surface area over which sweat is concentrated. Thus, if sweat is generated more in one area of ​​the body, the top layer distributes this sweat over a larger area, thereby enhancing the body's natural sweating mechanism. While not wishing to be bound by any particular theory, the inventors believe that the body's sweating mechanism may be enhanced for two main reasons. First, sweat is prevented from uncomfortably saturating a small area of ​​the fabric. Second, because sweat is continuously spread over a larger surface area, a larger area of ​​skin benefits from the moisturizing effect. Furthermore, evaporation of sweat occurs in the top layer, rather than on the skin surface, preventing the deposition of potentially allergenic salt residues on the skin.

[0086]

[0093] The layered nature of the fabric also allows sweat evaporation to occur from the fabric rather than from the skin surface, reducing skin irritation when the fabric is worn for extended periods. The benefit of allowing sweat to evaporate from the fabric is that it prevents the accumulation of salt residue from the skin surface, which can cause allergic reactions. Bacteria on the skin surface can grow in the presence of excess sweat, some of which can produce pathogens or antigens. These substances can be absorbed by the skin and induce inflammation. Therefore, effective sweat management can prevent sweat residue from exacerbating skin inflammation.

[0087]

[0094] The composition of the fabric of the first aspect of the present disclosure can also be selected to adjust thermal conductivity to account for seasonal changes. Thermal conductivity depends on the moisture content of the fabric. Higher moisture regain materials can have higher moisture contents. The top layer of the fabric can include regenerated cellulose fibers, which have a higher moisture regain. However, the exact composition of the top layer of the fabric can be changed to achieve higher or lower moisture regain and thus adjust thermal conductivity. The amounts by weight of the first, second, and third yarns in the fabric can also be adjusted to provide "summer" and "winter" fabric compositions.

[0088]

[0095] The elastic fibers in the middle layer provide elasticity to the fabric, thereby enhancing comfort.

[0089]

[0096] In some embodiments, the PLA fibers of the first yarn can have an X-shaped, I-shaped, Y-shaped, M-shaped, O-shaped, U-shaped, or honeycomb-shaped cross section. The PLA fibers of the first yarn can have an X-shaped cross section. This cross-sectional configuration provides multiple spaces along the length of the first yarn, which promote capillary action, enhancing its ability to wick moisture. The humid environment surrounding the skin can also be optimized when the top layer has a high moisture regain.

[0090]

[0097] In some embodiments, the fabric is a knitted fabric, such as, for example, a jersey fabric. The jersey fabric can be a single knit jersey fabric. The jersey fabric can be a double knit jersey fabric.

[0091]

[0098] The first and / or third yarn can be looped together with an elastic yarn. The first yarn can be looped together with an elastic fiber. The third yarn can be looped together with an elastic yarn. The first yarn can be looped together with an elastic yarn, and the third yarn can be looped together with an elastic yarn. The first and third yarns can be looped together with the same type of elastic yarn or different elastic yarns. The elastic yarn can be as described above with respect to the second yarn. The elastic yarn can be an elastoolefin. The yarn count of the elastic yarn can be 42D or about 4.7 tex. When the first and / or third yarns can be looped together with an elastic yarn, the second yarn can be a regenerated cellulose fiber such as modal. In this context, "looped" refers to the first and / or third yarn and the elastic yarn being knitted together.

[0092]

[0099] In some embodiments, the fabric comprises: a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric that contacts the wearer's skin during use, thereby protecting the wearer from sweat; a second yarn comprising elastic fibers or regenerated cellulose fibers, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an outermost layer of the fabric furthest from the wearer's skin, which receives and retains sweat removed from the wearer's skin and prevents the sweat from coming into contact with the wearer's skin; and the sweat present in the third yarn generates water vapor, thereby providing a moisturizing effect to the wearer's skin without giving the wearer a clammy feeling.

[0093]

[0100] In some embodiments, the fabric comprises: a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric that contacts the wearer's skin during use, thereby protecting the wearer from sweat; a second yarn comprising an elastic fiber, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an outermost layer of the fabric furthest from the wearer's skin, which receives and retains sweat removed from the wearer's skin and prevents the sweat from coming into contact with the wearer's skin; and the sweat present in the third yarn generates water vapor, thereby providing a moisturizing effect to the wearer's skin without giving the wearer a clammy feeling.

[0094]

[0101] In the embodiments of

[0099] or

[0100] , the cross section of the PLA fiber may be X-shaped.

[0095]

[0102] In the embodiments of

[0099] or

[0100] , the regenerated cellulose fibers may be modal.

[0096]

[0103] In the embodiment of

[0099] or

[0100] , the Modal may have a moisture content of about 13%.

[0097]

[0104] In the embodiments of

[0099] or

[0100] , the first yarn may constitute about 15% to 60% by weight of the fabric or about 30% to 60% by weight of the fabric, the second yarn may constitute about 5% to 20% by weight of the fabric, and the third yarn may constitute about 15% to about 60% by weight of the fabric or about 30% to 60% by weight of the fabric.

[0098]

[0105] In the embodiments of

[0099] or

[0100] , the first yarn may be from about 50 denier to about 75 denier, the second yarn may be from about 33 denier to about 55 denier, and the third yarn may have a thread count of from about 60S to about 80S or from about 20S to about 100S or equivalently from about 9.7 tex to about 7.3 tex or from about 5 tex to about 30 tex.

[0099]

[0106] One embodiment of the fabric of the first aspect of the present disclosure is as follows.

[0100] [Table 1]

[0101]

[0107] Another embodiment of the fabric of the first aspect of the present disclosure is as follows.

[0102] [Table 2]

[0103]

[0108] Another embodiment of the fabric of the first aspect of the present disclosure is as follows.

[0104] [Table 3]

[0105]

[0109] Another embodiment of the fabric of the first aspect of the present disclosure is as follows.

[0106] [Table 4]

[0107]

[0110] Another embodiment of the fabric of the first aspect of the present disclosure is as follows.

[0108] [Table 5]

[0109]

[0111] Another embodiment of the fabric of the first aspect of the present disclosure is as follows.

[0110] [Table 6]

[0111]

[0112] As such, the fabrics of the present disclosure may have one or more of the following advantages: 1. By using hydrophobic, low-moisture PLA as the bottom layer of the fabric, ideal skin temperature can be maintained through evaporative cooling. 2. Regulating skin temperature by providing adjustable thermal conductivity. 3. Maintaining skin moisture levels by managing perspiration to achieve dry and moisturized skin by establishing a microclimate between the skin and the fabric. 4. Maintaining the skin's pH level by using PLA (pH 5.5) in the bottom layer of the fabric. 5. Prevent allergic reactions by absorbing and evaporating sweat through the clothing, rather than on the skin, to avoid salt residue remaining on the skin surface.

[0112] Fabric Creation of the Disclosed Invention

[0113] Fabrics according to the present disclosure may be made using a single face flat knitting machine equipped with a triknit yarn feeder, such as the triknit yarn feeder disclosed in Chinese Patent Application No. ZL201922271717.0. The knitting parameters for making a fabric according to one embodiment of the present disclosure are as follows:

[0113] [Table 7]

[0114]

[0114] The method is as follows: 1. Pre-treat in a heat treater at 130°C with a machine speed of 20 yards per minute. 2. Dye with reactive dye for 4 or 8 hours. Dyeing process: Degreasing → Dye is added to the batch → Dewatering → Drying the fabric. 3. Finished by heat treatment machine at 120°C, machine speed is 20 yards per minute.

[0115] How to Treat Skin Conditions In another aspect, the present disclosure provides a method of treating dermatitis in a subject in need thereof, the method comprising applying the fabric of the first aspect or the clothing item of the second aspect to an area of ​​the subject's body suffering from dermatitis. Applying the fabric of the first aspect or the clothing item of the second aspect to an area of ​​the subject's body may comprise wearing the clothing item comprising the fabric of the first aspect. Also disclosed herein is the fabric of the first aspect or the clothing item of the second aspect for use in treating dermatitis. Also disclosed herein is the use of the fabric of the first aspect in making clothing for treating dermatitis.

[0116]

[0116] In one embodiment, when used in the treatment of dermatitis, the fabric of the first aspect of the present disclosure or the article of clothing of the second aspect of the present disclosure is applied to an area of ​​a subject's body, whereby the third yarn comprising regenerated cellulose fibers forms the top outer layer furthest from the skin and the first yarn comprising PLA forms the bottom layer, i.e., the layer in contact with the skin. The duration for which the fabric is applied to the skin or the article of clothing is worn and the wearer's degree of sweating during this time can be determined by a physician or dermatologist.

[0117] In another embodiment, when used in the treatment of dermatitis, the fabric of the first aspect of the present disclosure or the article of clothing of the second aspect of the present disclosure is intended to be worn initially with the top layer in direct contact with the patient's skin. Therefore, the patient may be subjected to various stimuli to induce sweating. Sweating may be induced by various methods, such as exercise, elevated room temperature, or immersing the patient's feet in a warm water bath. The duration and degree of sweating may be determined by the attending physician or dermatologist. Once the fabric has reached a sufficient moisture content, the fabric may be removed by the patient, turned inside out, and reapplied so that the regenerated cellulose fiber layer is the top layer and the PLA layer is the bottom layer, i.e., the layer in contact with the skin. Thus, in a further aspect of the present disclosure, there is provided a method of wearing an article of clothing according to the second aspect of the present disclosure, wherein the article of clothing comprises the fabric of the first aspect of the present disclosure, including a top layer, a middle layer and a bottom layer as defined above in relation to the first aspect, the method comprising: (i) wearing the article of clothing in a first orientation so that the top layer of fabric is in contact with the wearer's skin; followed by (ii) wearing the article of clothing in a second orientation so that the bottom layer of fabric is in contact with the wearer's skin.

[0118] In the methods and uses of the present invention, the dermatitis may be selected from the group consisting of atopic dermatitis (eczema), contact dermatitis, photosensitive dermatitis, diaper dermatitis, dyshidrotic dermatitis, neurodermatitis, nummular dermatitis, perioral / periorificial dermatitis, seborrheic dermatitis, venous stasis or sinking dermatitis, metabolic dermatitis, chronic superficial scaly dermatitis, asteatotic dermatitis, erythrodermic dermatitis and stasis dermatitis. The dermatitis may be atopic dermatitis (i.e., eczema).

[0119] The wicking properties of the PLA layer allow sweat to be continuously drawn away from the wearer's skin and into the recycled fiber layer, so that the recycled fiber layer is constantly replenished. This has the effect of placing a moisturizing layer over the skin that acts as a moisturizer without placing the patient in contact with a dry surface and feeling damp. If water were placed in direct contact with the skin (as in existing treatments), the stratum corneum of the skin would break down, causing wrinkles and discomfort. Furthermore, human skin can be irritated by direct contact with water due to different pH levels and mineral concentrations. This irritation can often ultimately prolong or even worsen eczema symptoms.

[0120]

[0120] The present disclosure may be defined by the numbered embodiments described below. 1.a. a first yarn comprising polylactic acid (PLA) fibers; b. a second yarn comprising an elastic fiber; c. a third yarn comprising regenerated cellulose fibers; Fabric including. 2. The fabric of embodiment 1, wherein the first yarn is a filament yarn. 3. The fabric of embodiment 1 or 2, wherein the cross section of the PLA fibers is X-shaped. 4. The fabric of any one of embodiments 1 to 3, wherein the first yarn is from about 40 denier to about 150 denier. 5. The fabric of any one of embodiments 1 to 4, wherein the first yarn is about 50 denier to about 75 denier. 6. The fabric of any one of embodiments 1 to 5, wherein the first yarn has a stitch length / 100 loops of about 20 cm to about 40 cm. 7. The fabric of any one of embodiments 1 to 6, wherein the first yarn has a stitch length / 100 loops of about 25 cm to about 35 cm. 8. The fabric of any one of embodiments 1 to 7, wherein the first yarn comprises about 15% to about 60% by weight of the fabric. 9. The fabric of any one of embodiments 1 to 8, wherein the first yarn comprises about 35% to about 55% by weight of the fabric. 10. The fabric of any one of embodiments 1 to 9, wherein the first yarn is made of PLA fiber. 11. The fabric of any one of embodiments 1-10, wherein the second yarn is a filament yarn. 12. The fabric of any one of embodiments 1-11, wherein the second yarn is from about 25 denier to about 65 denier. 13. The fabric of any one of embodiments 1-12, wherein the second yarn is from about 33 denier to about 55 denier. 14. The fabric of any one of embodiments 1 to 13, wherein the second yarn has a stitch length / 100 loops of about 5 cm to about 20 cm. 15. The fabric of any one of embodiments 1-14, wherein the second yarn has a stitch length / 100 loops of about 10 cm to about 15 cm. 16. The fabric of any one of embodiments 1-15, wherein the second yarn comprises about 5% to about 20% by weight of the fabric. 17. The fabric of any one of embodiments 1-16, wherein the second yarn comprises about 8% to about 15% by weight of the fabric. 18. The fabric of any one of embodiments 1 to 17, wherein the elastic fibers are selected from the group consisting of elastoolefins, elastanes, diene elastic fibers, polyetherester elastic fibers, and polyolefin elastomeric fibers. 19. The fabric of any one of embodiments 1-18, wherein the second yarn comprises elastane. 20. The fabric of any one of embodiments 1 to 19, wherein the third yarn has a moisture regain of about 10% to about 20%. 21. The fabric of any one of embodiments 1-20, wherein the third yarn is a spun yarn. 22. The fabric of any one of embodiments 1-21, wherein the third yarn further comprises polyester or cotton. 23. The fabric of any one of embodiments 1 to 22, wherein the regenerated cellulose fibers are modal, tencel, rayon, cuprammonium fibers, or combinations thereof. 24. The fabric of any one of embodiments 1 to 23, wherein the regenerated cellulose fiber is modal. 25. The fabric of any one of embodiments 1 to 24, wherein the third yarn comprises modal. 26. The fabric of any one of embodiments 1 to 25, wherein the third yarn comprises about 30% to about 80% by weight of the fabric. 27. The fabric of any one of embodiments 1 to 26, wherein the third yarn constitutes about 33% to about 53% by weight of the fabric. 28. The fabric of any one of embodiments 1 to 27, wherein the third yarn has a stitch length / 100 loops of about 20 cm to about 40 cm. 29. The fabric of any one of embodiments 1 to 28, wherein the third yarn has a stitch length per 100 loops of about 26 cm to about 36 cm. 30. The fabric of any one of embodiments 1-29, wherein the third yarn has a thread count of about 5 tex to about 30 tex. 31. The fabric of any one of embodiments 1-29, wherein the third yarn has a thread count of about 10 tex to about 7 tex. 32. The fabric of any one of embodiments 1-31, wherein the second yarn is woven between the first yarn and the third yarn. 33. The fabric of any one of embodiments 1-32, wherein the first, second, and third yarns are present as layers. 34. The fabric of embodiment 32 or 33, wherein the fabric consists of three layers. 35. The fabric of embodiment 32 or 33, wherein the first yarn forms the bottom layer, the second yarn forms the middle layer, and the third yarn forms the top layer. 36. The fabric of any one of embodiments 1 to 35, wherein the fabric is a knitted fabric. 37. The fabric of embodiment 36, wherein the knitted fabric is a jersey fabric. 38. The dough of any one of embodiments 1 to 37, wherein the dough is a moisturizing dough. 39. An article of clothing when produced from or comprising the fabric of any one of embodiments 1-38. 40. A fabric, a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric adapted to contact the skin of a wearer; a second yarn comprising elastic fibers or regenerated cellulose fibers, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an uppermost outer layer of the fabric that is furthest from the wearer's skin; and 40. The article of clothing of embodiment 39, comprising a fabric comprising or consisting of: 41. A fabric, a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of a fabric adapted to contact the skin of a wearer; a second yarn comprising an elastic fiber, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an uppermost outer layer of the fabric that is furthest from the wearer's skin; and 41. The article of clothing of embodiment 39 or 40, comprising a fabric comprising or consisting of: 42. The article of apparel of any one of embodiments 39-41, selected from the group consisting of a shirt, a running shirt, a jersey, pajamas, a maillot, a fleece, shorts, pants, a hood, a running hat, a skull cap, a helmet liner, a mask, a headband, and socks. 43. A method of treating dermatitis in a subject in need thereof, comprising applying the fabric of any one of embodiments 1-38 or the article of clothing of any one of embodiments 39-42 to an area of ​​the subject's body suffering from dermatitis. 44. The method of embodiment 43, wherein the dermatitis is eczema. [Example]

[0121] Example The present inventors conducted a clinical pilot study to compare the effects of functional T-shirts for patients with atopic dermatitis (AD) in summer and winter. Nine outpatients with AD wore Comfiknit Atopic Eczema® T-shirts (shirts made from fabric according to the first aspect of the present disclosure) as underwear for four weeks in each season to examine the effects and seasonal differences. To determine the effects of wearing Comfiknit T-shirts on AD, AD severity, itching, skin condition, and satisfaction were also evaluated.

[0122] Materials and Methods material Comfiknit Atopic Eczema® T-shirts were selected for the study. The T-shirts were made with three layers. The bottom layer, which comes into contact with the skin, was made of polylactic acid (PLA). PLA is a hydrophobic fiber. PLA with a crisscross section was used in this study to wick excess sweat away from the skin. The middle layer was made of spandex, which provides elasticity. The outermost top layer was made of modal, a hydrophilic fiber that promotes moisture retention by absorbing and retaining sweat. The T-shirts were made in two patterns: winter and summer. In both T-shirts, the stitching was on the outside to avoid contact with the skin. The winter T-shirt had long sleeves, a crew neck, and a green color. The summer T-shirt had short sleeves, a V-neck, and a white color (Figure 6). The yarns used in these T-shirts were the same, but the thicknesses varied due to the different blends. The T-shirt compositions are shown in Table 8 below and Figures 1-4.

[0123] [Table 8]

[0124] Study Protocol Ten adult outpatients with AD participated in this study. WBC ( / μL), Eo (%), Eo ( / μL), TARC (pg / ml), and IgE (IU / ml) were assessed at baseline. This study was approved by the Institutional Review Board of Nagasaki University and registered with the University Hospital Medical Information Network Clinical Trial Registry (UMIN-CTR; UMIN000042252).

[0125] At the start of the study, patients were given three Comfiknit Atopic Eczema® T-shirts to wear as underwear during the study period. The T-shirt size was selected by the patient through try-on or visual inspection. Patients were not allowed to wash the T-shirts using fabric softener. Otherwise, the T-shirts were washed and ironed as usual. Patients wore the T-shirts for four weeks each during the winter and summer seasons to account for seasonal changes. One patient dropped out of the study during the winter period, but the other nine patients remained stable during both periods. EASI (Eczema Area and Severity Index), POEM (Patient-Oriented Eczema Measure), itch VAS (Visual Analog Scale), SCWC (Stratum Corneum Hydration Content), skin pH, and skin bacterial culture were assessed before and four weeks after the intervention (see Figure 7).

[0126] SCWC was determined by measuring hydration (μS) using a SKICON-200EX-USB (YAYOI Co., Ltd., Tokyo, Japan). Skin pH was determined using a LAQUA F-74 (HORIBA, Advanced Techno, Co., Ltd., Kyoto, Japan). SCWC and skin pH were detected at the center of the chest. Bacterial culture was detected at the center of the back. The approved TSQM-9 (Medication Treatment Satisfaction Questionnaire-9) was used with permission to assess satisfaction with wearing the T-shirt. Because the TSQM-9 scale measures satisfaction with medication, the results of the TSQM-9 in this study were considered to indirectly indicate satisfaction. AD treatment did not change during the winter or summer study.

[0127] result Patient characteristics Patient characteristics are summarized in Table 9. Nine of the participating patients completed the study (one patient's characteristics are not shown because he dropped out of the study). There were six men and three women, and the mean age was 39.3 years. All patients participated in the treatment of AD at the Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. All patients received standard AD treatment, with four receiving dupilumab treatment, two receiving ultraviolet light treatment, and one receiving oral cyclosporine. The mean pre-study blood test results were WBC 6578 / μL, Eo 4.4%, Eo 275 / μL, TARC 1990 pg / mL, and IgE 8767 IU / mL, respectively.

[0128] [Table 9]

[0129] result The outcome measures are presented in Tables 10 and 11 and FIG. 8. The mean EASI scores after 4 weeks of wearing the Comfiknit Atopic Eczema® T-shirt were lower than those at week 0 in both winter and summer. In particular, patients with an EASI score of >21 at week 0 and classified as having severe AD tended to have lower scores after 4 weeks of wearing the T-shirt (Table 10, FIG. 8A). The mean POEM scores after 4 weeks of wearing the T-shirt were also lower than those at week 0 in both winter and summer. In terms of specific characteristics, patients with high POEM scores at week 0 had lower scores at week 4, but Patient A in winter and Patients G and H in summer showed high POEM scores at week 4 (Table 10, FIG. 8B). The mean VAS scores after 4 weeks of wearing these T-shirts were lower than those at week 0 in both winter and summer. However, the change in itch VAS scores varied among individuals. There was no correlation between itch and AD severity (Table 10, Figure 8C). Skin pH remained slightly acidic in most patients throughout both studies. In winter, a pH of 10.73 was observed in patient E at week 0, which may have been due to measurement error (Table 10, Figure 8D). SCWC was lower in winter and higher in summer for most patients at week 0. The mean SCWC after 4 weeks of wearing the T-shirt was higher than at week 0 in both periods, but individual scores were lower in approximately half of the patients after 4 weeks (Table 10, Figure 8E). The mean TSQM-9 scores for wearing the T-shirt were 56.6 for effectiveness, 65.0 for convenience, and 56.4 for overall satisfaction in summer, and 73.9 for effectiveness, 85.6 for convenience, and 70.0 for overall satisfaction in winter (Table 10, Figure 8F). Bacterial cultures showed species changes at weeks 0 and 4 in both summer and winter, but did not show a consistent trend (Table 11).

[0130] [Table 10]

[0131] [Table 11]

[0132] [Table 12]

[0133] Consideration In this study, the intervention effect of Comfiknit Atopic Eczema® T-shirts was tested in the same nine patients in two seasons, summer and winter. These T-shirts were expected to absorb excess sweat from the skin surface and retain moisture inside the garment. It was hypothesized that the better water absorption and rapid drying properties of these T-shirts may contribute to avoiding disease exacerbations. The mean SCWC after 4 weeks of intervention was high in both summer and winter, indicating that dry skin was prevented by wearing these T-shirts.

[0134] There was no change in pH as a result of wearing the T-shirt; the skin pH remained slightly acidic (Table 10, Figure 8E), and there was no apparent effect on the results of skin bacterial culture (Table 11). Normal skin pH is 4.5 to 6.0. Acidic pH is involved in skin protection by providing a favorable environment for normal microflora and maintaining the barrier structure of the stratum corneum. Exacerbation of AD is associated with the proliferation of Staphylococcus aureus, which results from a neutral skin pH. Therefore, the skin pH and bacterial culture results are consistent with the fact that AD was not exacerbated.

[0135]

[0130] The TSQM-9 scores revealed a favorable level of convenience in both winter and summer. Furthermore, the TSQM-9 scores were higher for all items in summer than in winter. The functional T-shirt can simply be worn instead of regular underwear, which is convenient and may increase support.

[0136]

[0131] Although the present disclosure has been described with reference to specific embodiments, it will be apparent to those skilled in the art that the present disclosure may be provided in many other forms.

Claims

1. a. a first yarn comprising polylactic acid (PLA) fibers; b. a second yarn comprising elastic fibers or regenerated cellulose fibers; c. a third yarn comprising regenerated cellulose fibers; and Fabric including.

2. The fabric of claim 1 , wherein the second yarn comprises an elastic fiber.

3. The fabric of claim 1 or 2, wherein the first yarns comprise from about 15% to about 60% by weight of the fabric.

4. The fabric according to any one of claims 1 to 3, wherein the first yarn is made of PLA fibre.

5. The fabric of any one of claims 1 to 4, wherein the second yarns constitute from about 5% to about 20% by weight of the fabric.

6. The fabric according to any one of claims 1 to 5, wherein the elastic fibres are selected from the group consisting of elastoolefins, elastanes, diene elastic fibres, polyetherester elastic fibres and polyolefin elastomeric fibres.

7. The fabric according to any one of claims 1 to 6, wherein the second yarn consists of elastane.

8. The fabric according to any one of claims 1 to 7, wherein the third yarn has a moisture regain of about 10% to about 20%.

9. The fabric according to any one of claims 1 to 8, wherein the regenerated cellulose fibers are modal, tencel, rayon, cuprammonium fibers, bamboo, cotton, or a combination thereof.

10. The fabric according to any one of claims 1 to 9, wherein the regenerated cellulose fibres are modal.

11. The fabric according to any one of claims 1 to 10, wherein the third yarn is made of modal.

12. The fabric of any one of claims 1 to 11, wherein the third yarns comprise from about 30% to about 80% by weight of the fabric.

13. The fabric according to any one of claims 1 to 12, wherein the second yarn is woven between the first yarn and the third yarn.

14. The fabric of any one of claims 1 to 13, wherein the first, second and third yarns are present as layers.

15. 15. The fabric of claim 14, wherein the first yarns form a bottom layer, the second yarns form a middle layer, and the third yarns form a top layer.

16. The fabric according to any one of claims 1 to 15, which is a knitted fabric.

17. 17. The fabric of claim 16, wherein the knitted fabric is a jersey fabric.

18. The fabric of any one of claims 1 to 17, wherein the first and / or third yarns are looped together with elastic fibers.

19. 19. An article of clothing when produced from or comprising the fabric of any one of claims 1 to 18.

20. A fabric, a first yarn comprising polylactic acid (PLA) fibers, the first yarn forming a bottom layer of the fabric adapted to contact the skin of a wearer; a second yarn comprising elastic fibers or regenerated cellulose fibers, the second yarn forming a middle layer of the fabric; a third yarn comprising regenerated cellulose fibers, the third yarn forming an outermost layer of the fabric that is furthest from the wearer's skin; and 20. The article of clothing of claim 19, comprising a fabric comprising or consisting of:

21. 21. The article of clothing of claim 19 or 20, selected from the group consisting of a shirt, a running shirt, a jersey, pajamas, a maillot, a fleece, shorts, pants, a hood, a running hat, a skull cap, a helmet liner, a mask, a headband, and socks.

22. 22. A method of treating dermatitis in a subject in need thereof, the method comprising applying a fabric according to any one of claims 1 to 18 or a garment according to any one of claims 19 to 21 to an area of ​​the subject's body suffering from the dermatitis.

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