Prosthetic repair fabric

Abstract

To provide a prosthetic repair fabric for repairing soft tissue and muscle wall defects.SOLUTION: The repair fabric includes a double bar warp knit mesh for use in the repair of soft tissue and muscle wall defects, including hernia repair and chest wall reconstruction. The repair fabric may be manufactured according to a first bar pattern chain of 4 / 24 / 64 / 26 / 86 / 46 / 8 of the first filament and a second bar pattern chain of 6 / 82 / 06 / 84 / 28 / 104 / 2 of the second filament. The diameter of the first filament is different from the diameter of the second filament.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present disclosure relates to prosthetic repair fabrics, and more particularly to prosthetic repair fabrics for use in soft tissue and muscle wall repair. [Background technology]

[0002] Implantable repair fabrics are employed by surgeons for soft tissue repair and reconstruction, including repair of anatomical defects such as soft tissue and muscle wall defects. The fabric is typically temporarily secured in place over, under, or within the defect by suturing, stapling, tacks, or other means. Integration of the tissue with the fabric, such as tissue ingrowth into and / or along the mesh fabric, ultimately completes the repair.

[0003] Soft tissue and muscle wall defect repair can be accomplished using a variety of surgical techniques, including open, laparoscopic, and hybrid (e.g., Kugel surgery) techniques. During open surgery, the repair fabric is placed through a relatively large incision made in the abdominal wall and tissue layers, and the defect is then filled or covered with the repair fabric. During laparoscopic and hybrid surgery, the fabric is collapsed, e.g., by rolling or folding, into a compact configuration for insertion into the surgical subject either directly through a relatively small incision or through an elongated laparoscopic cannula placed through the incision.

[0004] Various repair fabrics are known and used for repairing soft tissue and muscle wall defects. BARD MESH and VISILEX, available from CR Bard, are examples of implantable fabrics that have been successfully used for soft tissue and muscle wall repair. Such fabrics are made from polypropylene monofilaments knitted into a mesh with pores or interstices that promote tissue ingrowth and integration with the fabric.

[0005] As tissue ingrowth occurs, scar tissue may form around the repair fabric, forming a scar plate. The volume and stiffness of the scar plate that forms around the fabric may be affected by a variety of factors, including the amount of foreign material introduced into the patient by the fabric. Summary of the Invention [Problem to be solved by the invention]

[0006] It is an object of the present disclosure to provide a prosthetic repair fabric for repairing soft tissue and muscle wall defects. [Means for solving the problem]

[0007] overview In one exemplary embodiment, an implantable prosthetic repair fabric includes a biocompatible implantable double-bar warp knit mesh manufactured according to a first bar pattern chain of 4 / 2 4 / 6 4 / 2 6 / 8 6 / 4 6 / 8 and a second bar pattern chain of 6 / 8 2 / 0 6 / 8 4 / 2 8 / 10 4 / 2. The mesh is knitted from first monofilaments having a first diameter and second monofilaments having a second diameter larger than the first diameter. The first monofilaments are knitted according to the first bar pattern chain, and the second monofilaments are knitted according to the second bar pattern chain.

[0008] In one exemplary embodiment, an implantable prosthetic repair fabric includes a knit mesh including a plurality of generally polygonal primary pores defined by knit strands of first filaments. A pair of respective second filaments extends across each primary pore to define a plurality of secondary pores within each primary pore. Each of the pair of second filaments extends substantially parallel to one another. The first filaments have a first diameter, and the second filaments have a second diameter greater than the first diameter.

[0009] In one exemplary embodiment, the implantable prosthetic repair fabric comprises a biocompatible implantable double-bar warp knit mesh manufactured according to a first bar pattern chain of 4 / 2 4 / 6 4 / 2 6 / 8 6 / 4 6 / 8 and a second bar pattern chain of 6 / 8 2 / 0 6 / 8 4 / 2 8 / 10 4 / 2. The mesh has a ball burst strength of 35 lbs to 42.4 lbs, a suture pull-out strength of 9 lbs to 11 lbs in the longitudinal direction and 7.5 lbs to 9.5 lbs in the transverse direction, and a tensile strength of 11.8 lbs to 16.8 lbs in the longitudinal direction and 34.2 lbs to 47.2 lbs in the transverse direction.

[0010] Various embodiments of the present disclosure will now be described, by way of example only, with reference to the accompanying drawings, in which: [Brief explanation of the drawings]

[0011] [Figure 1] FIG. 1 is an enlarged plan view of a double-bar warp knit mesh fabric according to an exemplary embodiment of the present disclosure. [Figure 2A] 2 shows a chain wrapping pattern for the mesh fabric of FIG. 1. [Figure 2B] 2 shows a chain wrapping pattern for the mesh fabric of FIG. 1. [Figure 3] FIG. 1 is a schematic diagram for determining the area of ​​a primary cell. DETAILED DESCRIPTION OF THE INVENTION

[0012] Detailed Description Embodiments of the present disclosure include prosthetic fabrics, including mesh fabrics, that are relatively flexible, thin, and lightweight, and meet the performance and physical characteristics for soft tissue repair and reconstructive procedures. Surgical repair fabrics can be used to reinforce and close soft tissue defects, and are particularly indicated for chest wall reconstruction and / or hernia repair, such as inguinal hernia repair. The mesh fabrics are formed from biocompatible, flexible, and strong implantable materials.

[0013] The mesh fabric may employ a knitted structure that provides relatively large openings or pores to ensure good visibility of the underlying anatomical structures without sacrificing the mechanical properties of the mesh. The porosity of the fabric allows for tissue infiltration to incorporate the prosthetic fabric. The knitted fabric is sufficiently strong and structured to eliminate or minimize the possibility of pullout of fixation fasteners, such as sutures, staples, and tacks. Flexible repair fabrics can be easily reduced in size for insertion into a surgical subject. In this manner, the flexible fabric can be folded into an elongated shape, such as a roll, and supported and advanced through a narrow laparoscopic cannula for use in laparoscopic surgery.

[0014] The mesh fabric employs a relatively lightweight, thinner, and / or more flexible fabric structure that is less likely to introduce foreign material into the patient than other repair fabrics. The porous prosthetic repair fabric allows for a rapid fibroblast response through the interstices of the mesh to form a secure fibrous / prosthetic layer. The fabric can provide a thinner, more adaptable scar plate that can result in a soft tissue or muscle wall repair that is relatively comfortable for the patient.

[0015] In one exemplary embodiment shown in Figure 1, the repair fabric comprises a knit mesh 10 including knitted strands of filaments 12 arranged in a uniform pattern defining larger primary pores 14. A pair of individual filaments 16 extends across the primary pores to define a plurality of smaller secondary pores 18 within the primary pores.

[0016] In the illustrated embodiment, the primary pores 14 are bounded by knit strands of filaments 12. However, it should be understood that one or more boundaries of the primary pores 14 can be defined by individual filaments, as would be apparent to one skilled in the art. As illustrated, the primary pores 14 can have a generally polygonal shape, such as a hexagon, diamond, or square, although aspects of the present disclosure are not limited thereto. In this regard, it should be understood that other pore shapes are contemplated, including, but not limited to, circular, non-circular, round, elliptical, etc., as would be apparent to one skilled in the art.

[0017] The prosthetic repair fabric may be configured to increase the fabric's flexibility and / or reduce the fabric's overall weight per unit area. Such characteristics may allow the repair fabric to be more easily folded for introduction into a patient. These characteristics may also allow for easier manipulation of the repair fabric around a surgical site within a patient. In one exemplary embodiment, the primary pores 14 have an area of ​​approximately 0.01032 to 0.01233 square inches. In this regard, less material may be used to produce a mesh of a given area, which may result in a lower weight mesh. Furthermore, the generally greater spacing between strands of filaments 12 associated with larger primary pores 14 may also contribute to a more flexible mesh. However, as will be apparent to those skilled in the art, the size of the primary pores may vary, and it should be understood that aspects of the present disclosure are not limited in this respect.

[0018] In some applications, it may be desirable to provide secondary pores 18 within the primary pores 14. In one exemplary embodiment shown in FIG. 1 , each primary pore 14 is subdivided into multiple secondary pores 18 by a pair of individual or single filaments 16. In the exemplary embodiment, the pair of filaments 16 divide the primary pore 14 into a pair of generally triangular secondary pores 20 and a generally rectangular secondary pore 22 located between the two generally triangular secondary pores 20. However, it should be understood that the shape of the secondary pores and / or the number of secondary pores within each primary pore can vary as desired, as would be apparent to one skilled in the art, and that aspects of the present disclosure are not limited in this respect.

[0019] 1 , a pair of individual filaments 16 extend substantially parallel to one another across the primary pore 14. As shown, a pair of parallel filaments 16 may be generally linearly aligned with a corresponding pair of filaments in an adjacent primary pore. However, it should be understood that the individual filaments may be positioned and oriented in other suitable arrangements, and aspects of the present disclosure are not limited in this respect.

[0020] The prosthetic repair fabric can be configured to be provisionally secured to tissue or muscle using a variety of fasteners, such as sutures, staples, spiral tacks, Q-rings, etc. The individual filaments 16 extending across the primary pores can provide additional features for engagement with fasteners used to secure the fabric. It should be understood that the repair fabric can be secured to tissue and / or mesh using fasteners, such as spiral tack and Q-ring structures, which have relatively small features for engaging and holding the repair fabric in place. The smaller secondary pores 18 associated with the individual filaments can be sufficiently strong and structured to provide improved engagement with fasteners to prevent or minimize pull-out. It should be understood that the size of the secondary pores can vary, and aspects of the present disclosure are not limited in this respect, as would be apparent to one skilled in the art.

[0021] Knit meshes can employ filaments of the same size or different relative sizes to adjust the mechanical properties of the fabric. In one exemplary embodiment, the mesh fabric can include first filaments 12 having a first diameter to form primary pores and second filaments 16 having a second diameter different from the first diameter that span the primary pores. In one embodiment, the second filaments 16 have a second diameter larger than the first diameter of the first filaments. Such a configuration can increase the stiffness of the mesh fabric, thereby improving the handleability of the mesh fabric. However, it should be understood that other configurations are also contemplated. For example, but not limited to, the diameter of the first filaments 12 can be larger than the diameter of the second filaments 16.

[0022] In one exemplary embodiment, the knit mesh 10 can be produced in a wrapping pattern by knitting a pattern in six courses over three needles using two partially threaded guide bars. The fabric structure can be an atlas type, where each knitted edge travels over three or more needles, which can prevent the mesh from fraying.

[0023] In one exemplary embodiment shown in FIG. 2 , the repair fabric may employ a double-bar warp knit mesh structure produced using two guide bars moving according to a first bar pattern chain (identified as reference numeral 24) of 4 / 2 4 / 6 4 / 2 6 / 8 6 / 4 6 / 8 and a second bar pattern chain (identified as reference numeral 26) of 6 / 8 2 / 0 6 / 8 4 / 2 8 / 10 4 / 2. The mesh may be knitted on a single-needle bar, 24-gauge Russell knitting machine. The mesh may be produced at approximately 34-36 courses per inch and approximately 12-17 wales per inch. However, it should be understood that any suitable knit pattern may be used to knit the mesh fabric, and aspects of the present disclosure are not limited in this respect, as would be apparent to one skilled in the art.

[0024] The knit mesh can be manufactured in a variety of widths, such as from 1 inch to 80 inches, as will be apparent to one skilled in the art, depending on the intended use for which the repair fabric is manufactured.

[0025] After knitting, the fabric can be washed to remove any residual processing lubricants or other contaminants. A cleaning agent such as Triton X-100 can be used to assist in the removal of such contaminants. As will be apparent to those skilled in the art, after washing, the mesh can be dried at a temperature below the heat-setting and melting temperature of the material.

[0026] Some embodiments of the knit mesh can be heat-set to impart shape memory to the mesh and to prosthetic fabrics formed from the mesh. In one exemplary embodiment, the fabric is heat-set to have a generally planar shape memory. In this manner, the fabric can be folded and inserted into a patient, then return to a planar configuration and properly positioned against the patient's tissue. It should be understood that other embodiments of the fabric may have shape memory corresponding to a non-planar configuration, or may have no shape memory at all, and aspects of the present disclosure are not limited in this respect.

[0027] If desired, the knit mesh can be heat-set under tension in a crochet hoop or tenter frame. Heat-setting can be performed while the mesh knit is stretched in a particular direction, facilitating the mesh setting into a particular configuration. In one exemplary embodiment, the knit mesh is stretched in the cross-knit direction while simultaneously partially relaxed or contracted to a certain point in the machine direction while heat is applied to set the mesh. However, it should be understood that other techniques apparent to those skilled in the art can also be used to heat-set the knit mesh, and aspects of the present disclosure are not limited in this respect.

[0028] In some applications, it may be desirable to smooth the knitted mesh to reduce the texture or surface roughness of the mesh. In one exemplary embodiment, the knitted mesh is lightly pressed between a pair of plates, including a heated plate, which presses against the rough surface of the mesh to reduce high spots on the mesh and heat-set the mesh to smooth its surface. However, it should be understood that any suitable process apparent to one skilled in the art may be used to smooth the fabric. For example, during the washing and drying process, the knitted mesh can be passed between a pair of heated rollers to smooth the fabric.

[0029] The filaments used to manufacture the repair fabric can contribute to the fabric's final mechanical properties. In one exemplary embodiment, the repair fabric is knitted using first filaments 12 having a diameter of approximately 0.0045 to 0.0051 inches (first bar pattern chain), preferably approximately 0.0048 inches, and second filaments 16 having a diameter of approximately 0.0063 to 0.0075 inches (second bar pattern chain), preferably approximately 0.0075 inches. Filaments of these diameters can contribute to improving the overall handleability and strength properties of the repair fabric. However, it should be understood that the fabric can be manufactured using filaments having any appropriate diameter, as would be apparent to one skilled in the art, suitable for the desired application, and that aspects of the present disclosure are not limited in this respect.

[0030] In one exemplary embodiment, the fabric has a thickness of about 0.022 to 0.024 inches, and preferably about 0.0225 to 0.0235 inches. In one exemplary embodiment, the fabric has a weight per unit area of ​​about 0.066 to 0.069 grams per square inch. However, it should be understood that the fabric can be manufactured to have any thickness and / or weight per unit area apparent to one of ordinary skill in the art that is suitable for the desired application, and that aspects of the present disclosure are not limited in this respect.

[0031] In one exemplary embodiment, the filaments used to manufacture the mesh fabric comprise polypropylene monofilaments, which are inert in the presence of infection, non-wettable, and have low foreign body reactivity. In one exemplary embodiment, the monofilaments are formed from Aran Biomedical ProTex Med polypropylene resins PPS50156 and PPS50157. In one embodiment, the first monofilament has a denier of approximately 98±11, and the second monofilament has a denier of approximately 240±20. In one embodiment, the first and second monofilaments have a tenacity of approximately 6.0 to 8.5 grams per denier, with a nominal tenacity of approximately 6.2 grams per denier. However, it should be understood that filaments of various configurations, properties, and / or materials can be employed to manufacture the fabric. For example, as will be apparent to one skilled in the art, the filaments can include multifilaments or monofilaments with different mechanical properties, and aspects of the present disclosure are not limited in this respect. [Example]

[0032] The following examples are illustrative only and are not intended to limit the scope of the present disclosure.

[0033] The physical properties of a representative double-bar warp knit mesh fabric made from 0.0048 inch (first bar) and 0.0075 inch (second bar) polypropylene monofilament according to the exemplary embodiment shown in Figures 1 and 2 (designated as Embodiment No. 1 in Table 1) were evaluated and compared to several known mesh fabrics (comparison mesh fabrics). Physical and performance properties tested included mesh thickness, pore size, mesh weight per unit area, suture pull-out strength, burst strength, tear resistance, tensile (breaking) strength, elongation at break, and stiffness. Test methods and results are shown in Table 1 below, where average results and ranges from several test samples are reported (ranges are shown in parentheses).

[0034] Suture pull-out strength: Mesh specimens measuring at least 1 inch x 1 inch (Embodiment No. 1) or at least 0.5 inches x 3 inches (Comparative Mesh Fabric) were prepared and clamped in the lower jaw of an MTS™ or equivalent tensile testing machine. The long dimension of the specimen should be parallel to the specimen's orientation designation (machine direction or cross direction). At least 0.5 inches (Embodiment No. 1) or at least 1 inch (Comparative Mesh Fabric) of the mesh was exposed above the jaws. A spring steel wire having a diameter of approximately 0.019 inches was placed through the mesh to simulate a suture. The wire was positioned 5 ± 1 mm from the edge of the mesh. The wire suture was looped back and both ends were attached to the upper jaw of the tensile machine. The suture was then pulled through the mesh at a rate of 5 inches per minute. Peak forces were recorded for 4 to 10 specimens tested in both the machine direction and the cross direction of the mesh, and the average force was calculated for a total of at least 10 measurements in each direction.

[0035] Pore ​​size: A sample of mesh was placed in an optical coordinate measuring device such as Tesa Vision (35x magnification).

[0036] For embodiment number 1, each primary pore has a generally hexagonal shape, including two generally triangular pores and a generally rectangular pore in the central region. The length L of each leg of the primary pore was measured between each pair of end points AB, BC, CD, DE, EF, and FA, as shown by the dashed lines in Figure 3. The pore area of ​​the primary pore was calculated based on the area of ​​the hexagon as follows: where L 平均 is the average length of each leg. Area=(L 平均 ) 2 ×(3√3) / 2 Three randomly selected primary cells (pores formed by loops or knots not being counted) of each of the four mesh samples were measured and the average of these combinations was calculated.

[0037] Tensile (breaking) strength and elongation at break: A mesh sample approximately 1 inch by 6 inches was placed in the pneumatic jaws of an MTS™ tensile tester or equivalent device. The sample was oriented so that the knit direction being tested was parallel to the 6-inch length. The ends of the 6-inch sample were gripped between the lower and upper jaws of the tester. Starting with a minimum separation of 2 inches, the sample was pulled at a constant rate of 12 inches per minute until the sample broke. The peak load and elongation at break were recorded. Samples were tested in both the cross and machine directions. The average was then calculated for at least 10 total measurements taken from 4 to 10 samples for each direction.

[0038] Mesh Thickness: Mesh samples were measured using a standard thickness snap gauge with a lightly spring-loaded pressure foot approximately 0.38 inches in diameter. The thickness was measured by lowering the foot onto the mesh. Measurements were taken to the nearest 0.0001 inch. A total of at least five meshes were measured, and the combined average was calculated.

[0039] Mesh Weight / Unit Area: Using a sample size of at least four meshes of at least about 2 inches by 2 inches, the weight of each sample was measured in grams to the nearest 0.0001 gram. The length and width dimensions were measured to the nearest 0.001 inch and the area was calculated by subtracting the area of ​​any rounded corners. The weight and unit area were used to calculate the weight per unit area for each sample. The weight per unit area for each sample was combined and averaged to calculate the average weight per unit area.

[0040] Burst Strength: This test method was derived from ANSI / AAMI VP20-1994 Section 8.3.3.2 and ASTM Ball Burst method D3787-01. A mesh sample was placed over a circular O-ring approximately 1 inch in diameter. The O-ring was placed in a grooved plate of a fixture with a hole in the center of the plate containing the O-ring. The fixture was attached to the lower jaw of an MTS™ or equivalent testing machine. The plate with the mesh was raised and clamped to the upper plate of the fixture, compressing the mesh sample. The upper plate also contained a hole with the same diameter as the lower plate. The hole in the fixture plate was sized to accept a round ball-tipped rod, only slightly larger than the rod, with a 0.38 inch diameter tip. The rod was connected to the upper jaw of the testing machine and moved down through the sample at a constant rate of 12 inches per minute. The peak load was recorded for at least 10 samples. The average burst strength was then calculated based on the peak load for the samples.

[0041] Tear Resistance: A mesh specimen approximately 2 inches by 2 inches was prepared. A 1-inch slit was cut at the midpoint of one side (the direction being tested) to form two mesh sections. One section of the mesh was clamped in the lower jaw of a pneumatic fixture, and the other section was clamped in the upper jaw of the fixture. Starting with the jaws at a minimum separation of 1 inch, the mesh was pulled at a rate of 12 inches per minute until tearing was complete. The peak force was recorded. The specimens were tested in the cross and machine directions (Embodiment No. 1) and the cross, machine, and diagonal directions (Comparative Mesh Fabric). An average of at least 10 measurements taken from 4 to 10 specimens for each group direction was then calculated.

[0042] [Table 1]

[0043] It should be understood that the foregoing description of the present disclosure is intended to be merely illustrative of the present disclosure, and that other equivalents, embodiments, and modifications of the present disclosure are within the scope of the present disclosure as set forth in the appended claims.

Claims

1. 1. An implantable prosthetic repair fabric, comprising: a biocompatible implantable double-bar warp knit mesh manufactured according to a first bar pattern chain of 4 / 2 4 / 6 4 / 2 6 / 8 6 / 4 6 / 8 and a second bar pattern chain of 6 / 8 2 / 0 6 / 8 4 / 2 8 / 10 4 / 2, wherein the mesh is knitted from first monofilaments having a first diameter and second monofilaments having a second diameter greater than the first diameter, the first monofilaments knitted according to the first bar pattern chain, and the second monofilaments knitted according to the second bar pattern chain.

2. The implantable prosthetic repair fabric of claim 1 , wherein the first and second monofilaments comprise polypropylene monofilaments.

3. 10. The implantable prosthetic repair fabric of claim 1, wherein the first monofilament has a diameter of about 0.0045 to 0.0051 inches and the second monofilament has a diameter of about 0.0063 to 0.0075 inches.

4. 4. The implantable prosthetic repair fabric of claim 3, wherein the first monofilament has a diameter of about 0.0048 inches and the second monofilament has a diameter of about 0.0075 inches.

5. 10. The implantable prosthetic repair fabric of claim 1, wherein the first monofilament has a denier of about 98±11 and the second monofilament has a denier of about 240±20.

6. 10. The implantable prosthetic repair fabric of claim 1, wherein the first and second monofilaments have a tenacity of about 6.00 to 8.50 grams per denier.

7. 7. The implantable prosthetic repair fabric of claim 6, wherein the first and second monofilaments have a tenacity of about 6.2 grams per denier.

8. 10. The implantable prosthetic repair fabric of claim 1, wherein the mesh has a knit structure comprising about 34-36 courses per inch and about 12-17 wales per inch.

9. The implantable prosthetic repair fabric of claim 1 , wherein the mesh has a weight per unit area of ​​about 0.0661 to 0.0690 grams per square inch.

10. The implantable prosthetic repair fabric of claim 1 , wherein the mesh has a thickness of about 0.022 to 0.024 inches.

11. The implantable prosthetic repair fabric of claim 1 , wherein the mesh has a ball burst strength of between 35 pounds and 42.4 pounds.

12. The implantable prosthetic repair fabric of claim 11 , wherein the mesh has a ball burst strength of between 36 and 40 pounds.

13. The implantable prosthetic repair fabric of claim 12, wherein the mesh has a ball burst strength of 36 to 39 pounds.

14. 10. The implantable prosthetic repair fabric of claim 1, wherein the mesh has a suture pull-out strength of 9 to 11 pounds in the longitudinal direction and 7.5 to 9.5 pounds in the transverse direction.

15. 15. The implantable prosthetic repair fabric of claim 14, wherein said mesh has a suture pull-out strength of about 10.2 pounds in said longitudinal direction and about 8.5 pounds in said transverse direction.

16. 10. The implantable prosthetic repair fabric of claim 1, wherein the mesh has a tensile strength of between 11.8 lbs and 16.8 lbs in the machine direction and between 34.2 lbs and 47.2 lbs in the cross direction.

17. 17. The implantable prosthetic repair fabric of claim 16, wherein the mesh has a tensile strength of about 14.3 pounds in the machine direction and about 40.7 pounds in the cross direction.

18. a knitted mesh including a plurality of generally polygonal primary pores defined by knitted strands of first filaments having a first diameter; a pair of individual second filaments extending across each primary pore to define a plurality of secondary pores within each primary pore, each of the pair of individual second filaments extending substantially parallel to one another, each of the second filaments having a second diameter greater than the first diameter; Implantable prosthetic repair fabrics including:

19. 20. The implantable prosthetic repair fabric of claim 18, wherein each primary pore has an area of ​​about 0.0103 to 0.0123 square inches.

20. 20. The implantable prosthetic repair fabric of claim 18, wherein the primary pores are generally hexagonal in shape.

21. 20. The implantable prosthetic repair fabric of claim 18, wherein the mesh is formed from braided first and second monofilaments.

22. 22. The implantable prosthetic repair fabric of claim 21, wherein the first and second monofilaments comprise polypropylene monofilaments.

23. 23. The implantable prosthetic repair fabric of claim 22, wherein the first monofilament has a diameter of about 0.0045 to 0.0051 inches and the second monofilament has a diameter of about 0.0063 to 0.0075 inches.

24. 23. The implantable prosthetic repair fabric of claim 22, wherein the first monofilament has a diameter of about 0.0048 inches and the second monofilament has a diameter of about 0.0075 inches.

25. 23. The implantable prosthetic repair fabric of claim 22, wherein the first monofilament has a denier of about 98±11 and the second monofilament has a denier of about 240±20.

26. 23. The implantable prosthetic repair fabric of claim 22, wherein the first and second monofilaments have a tenacity of about 6.00 to 8.50 grams per denier.

27. 23. The implantable prosthetic repair fabric of claim 22, wherein the first and second monofilaments have a tenacity of about 6.2 grams per denier.

28. 20. The implantable prosthetic repair fabric of claim 18, wherein the mesh has a knit structure comprising about 34-36 courses per inch and about 12-17 wales per inch.

29. 20. The implantable prosthetic repair fabric of claim 18, wherein the mesh has a weight per unit area of ​​about 0.0661 to 0.0690 grams per square inch.

30. 20. The implantable prosthetic repair fabric of claim 18, wherein the mesh has a thickness of about 0.022 to 0.024 inches.

31. 1. An implantable prosthetic repair fabric comprising a biocompatible implantable double bar warp knit mesh manufactured according to a first bar pattern chain of 4 / 2 4 / 6 4 / 2 6 / 8 6 / 4 6 / 8 and a second bar pattern chain of 6 / 8 2 / 0 6 / 8 4 / 2 8 / 10 4 / 2, said mesh having a ball burst strength of 35 lbs to 42.4 lbs, a suture pull-out strength of 9 lbs to 11 lbs in the machine direction and 7.5 lbs to 9.5 lbs in the cross direction, and a tensile strength of 11.8 lbs to 16.8 lbs in the machine direction and 34.2 lbs to 47.2 lbs in the cross direction.

32. 32. The implantable prosthetic repair fabric of claim 31, wherein the mesh has a ball burst strength of 36 to 39 pounds.

33. 32. The implantable prosthetic repair fabric of claim 31, wherein said mesh has a suture pull-out strength of about 10.2 pounds in said longitudinal direction and about 8.5 pounds in said transverse direction.

34. 32. The implantable prosthetic repair fabric of claim 31, wherein said mesh has a tensile strength of about 14.3 pounds in said machine direction and about 40.7 pounds in said cross direction.

35. 32. The implantable prosthetic repair fabric of claim 31 , wherein the mesh is knitted from first monofilaments having a first diameter and second monofilaments having a second diameter larger than the first diameter, the first monofilaments knitted according to the first bar pattern chains, and the second monofilaments knitted according to the second bar pattern chains.

36. 32. The implantable prosthetic repair fabric of claim 31, wherein the mesh has a knit structure comprising about 34-36 courses per inch and about 12-17 wales per inch.

37. 32. The implantable prosthetic repair fabric of claim 31, wherein the mesh has a weight per unit area of ​​about 0.0661 to 0.0690 grams per square inch.

38. 32. The implantable prosthetic repair fabric of claim 31, wherein the mesh has a thickness of about 0.022 to 0.024 inches.

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